A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins

Ackloo, Suzanne (ORCID:0000000296961839); Li, Fengling; Szewczyk, Magda; Seitova, Almagul; Loppnau, Peter; Zeng, Hong; Xu, Jin; Ahmad, Shabbir; Arnautova, Yelena; Baghaie, A.; Beldar, Serap; Bolotokova, Albina; Centrella, Paolo; Chau, Irene; Clark, Matthew (ORCID:0009000295778685); Cuozzo, John (ORCID:0000000262290395); Dehghani-Tafti, Saba; Disch, Jeremy (ORCID:0000000203571672); Dong, Aiping; Dumas, Antoine; Feng, Jianwen (ORCID:0000000312217605); Ghiabi, Pegah; Gibson, Elisa (ORCID:000000027112337X); Gilmer, Justin; Goldman, Brian; Green, Stuart (ORCID:0000000229609683); Guié, Marie-Aude; Guilinger, John; Harms, Nathan; Herasymenko, Oleksandra; Houliston, Scott; Hutchinson, Ashley; Kearnes, Steven (ORCID:0000000345794388); Keefe, Anthony; Kimani, Serah (ORCID:0000000269603833); Kramer, Trevor; Kutera, Maria; Kwak, Haejin; Lento, Cristina; Li, Yanjun; Liu, Jenny; Loup, Joachim; Machado, Raquel (ORCID:0000000159122991); Mulhern, Christopher; Perveen, Sumera; Righetto, Germanna; Riley, Patrick (ORCID:0000000307970272); Shrestha, Suman; Sigel, Eric; Silva, Madhushika; Sintchak, Michael (ORCID:0000000329476566); Slakman, Belinda (ORCID:0000000296219589); Taylor, Rhys; Thompson, James; Torng, Wen (ORCID:0000000288774785); Underkoffler, Carl; von Rechenberg, Moritz; Walsh, Ryan (ORCID:0000000333085496); Watson, Ian; Wilson, Derek (ORCID:0000000270126085); Wolf, Esther; Yadav, Manisha (ORCID:0000000165597774); Yazdi, Aliakbar; Zhang, Junyi; Zhang, Ying; Santhakumar, Vijayaratnam (ORCID:000000027001557X); Edwards, Aled (ORCID:0000000247826016); Barsyte-Lovejoy, Dalia; Schapira, Matthieu (ORCID:0000000210473309); Brown, Peter; Halabelian, Levon (ORCID:0000000343613619); Arrowsmith, Cheryl

doi:10.1021/acs.jmedchem.4c02010

DOE OSTI · 3675870

A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins

Ackloo, Suzanne (ORCID:0000000296961839)·Li, Fengling·Szewczyk, Magda·Seitova, Almagul·Loppnau, Peter·Zeng, Hong·Xu, Jin·Ahmad, Shabbir·Arnautova, Yelena·Baghaie, A.·Beldar, Serap·Bolotokova, Albina·Centrella, Paolo·Chau, Irene·Clark, Matthew (ORCID:0009000295778685)·Cuozzo, John (ORCID:0000000262290395)·Dehghani-Tafti, Saba·Disch, Jeremy (ORCID:0000000203571672)·Dong, Aiping·Dumas, Antoine·Feng, Jianwen (ORCID:0000000312217605)·Ghiabi, Pegah·Gibson, Elisa (ORCID:000000027112337X)·Gilmer, Justin·Goldman, Brian·Green, Stuart (ORCID:0000000229609683)·Guié, Marie-Aude·Guilinger, John·Harms, Nathan·Herasymenko, Oleksandra·Houliston, Scott·Hutchinson, Ashley·Kearnes, Steven (ORCID:0000000345794388)·Keefe, Anthony·Kimani, Serah (ORCID:0000000269603833)·Kramer, Trevor·Kutera, Maria·Kwak, Haejin·Lento, Cristina·Li, Yanjun·Liu, Jenny·Loup, Joachim·Machado, Raquel (ORCID:0000000159122991)·Mulhern, Christopher·Perveen, Sumera·Righetto, Germanna·Riley, Patrick (ORCID:0000000307970272)·Shrestha, Suman·Sigel, Eric·Silva, Madhushika·Sintchak, Michael (ORCID:0000000329476566)·Slakman, Belinda (ORCID:0000000296219589)·Taylor, Rhys·Thompson, James·Torng, Wen (ORCID:0000000288774785)·Underkoffler, Carl·von Rechenberg, Moritz·Walsh, Ryan (ORCID:0000000333085496)·Watson, Ian·Wilson, Derek (ORCID:0000000270126085)·Wolf, Esther·Yadav, Manisha (ORCID:0000000165597774)·Yazdi, Aliakbar·Zhang, Junyi·Zhang, Ying·Santhakumar, Vijayaratnam (ORCID:000000027001557X)·Edwards, Aled (ORCID:0000000247826016)·Barsyte-Lovejoy, Dalia·Schapira, Matthieu (ORCID:0000000210473309)·Brown, Peter·Halabelian, Levon (ORCID:0000000343613619)·Arrowsmith, Cheryl

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Ackloo, Suzanne (ORCID:0000000296961839), Li, Fengling, Szewczyk, Magda, Seitova, Almagul, Loppnau, Peter, Zeng, Hong, Xu, Jin, Ahmad, Shabbir, Arnautova, Yelena, Baghaie, A., Beldar, Serap, Bolotokova, Albina, Centrella, Paolo, Chau, Irene, Clark, Matthew (ORCID:0009000295778685), Cuozzo, John (ORCID:0000000262290395), Dehghani-Tafti, Saba, Disch, Jeremy (ORCID:0000000203571672), Dong, Aiping, Dumas, Antoine, Feng, Jianwen (ORCID:0000000312217605), Ghiabi, Pegah, Gibson, Elisa (ORCID:000000027112337X), Gilmer, Justin, Goldman, Brian, Green, Stuart (ORCID:0000000229609683), Guié, Marie-Aude, Guilinger, John, Harms, Nathan, Herasymenko, Oleksandra, Houliston, Scott, Hutchinson, Ashley, Kearnes, Steven (ORCID:0000000345794388), Keefe, Anthony, Kimani, Serah (ORCID:0000000269603833), Kramer, Trevor, Kutera, Maria, Kwak, Haejin, Lento, Cristina, Li, Yanjun, Liu, Jenny, Loup, Joachim, Machado, Raquel (ORCID:0000000159122991), Mulhern, Christopher, Perveen, Sumera, Righetto, Germanna, Riley, Patrick (ORCID:0000000307970272), Shrestha, Suman, Sigel, Eric, Silva, Madhushika, Sintchak, Michael (ORCID:0000000329476566), Slakman, Belinda (ORCID:0000000296219589), Taylor, Rhys, Thompson, James, Torng, Wen (ORCID:0000000288774785), Underkoffler, Carl, von Rechenberg, Moritz, Walsh, Ryan (ORCID:0000000333085496), Watson, Ian, Wilson, Derek (ORCID:0000000270126085), Wolf, Esther, Yadav, Manisha (ORCID:0000000165597774), Yazdi, Aliakbar, Zhang, Junyi, Zhang, Ying, Santhakumar, Vijayaratnam (ORCID:000000027001557X), Edwards, Aled (ORCID:0000000247826016), Barsyte-Lovejoy, Dalia, Schapira, Matthieu (ORCID:0000000210473309), Brown, Peter, Halabelian, Levon (ORCID:0000000343613619), Arrowsmith, Cheryl. 2024-11-04. A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins. https://doi.org/10.1021/acs.jmedchem.4c02010

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