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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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DOE OSTI2025

The role of AdhE mutations in Thermoanaerobacterium saccharolyticum

ABSTRACT Thermoanaerobacterium saccharolyticum is a thermophilic anaerobic bacterium that natively ferments a variety of hemicellulose substrates to organic acids and alcohols. It has recently been engineered to produce ethanol at high yield and titer; however, it uses a unique metabolic pathway for ethanol production that is poorly characterized. One of the distinctive aspects of this pathway is the presence of acetyl-CoA as an intermediate metabolite. In this organism, acetyl-CoA is converted to ethanol by a bifunctional AdhE enzyme. This enzyme has been a frequent target for mutations, and in many cases, the function of these mutations was unknown. Using a combination of genetic modifications, enzyme assays, and computational analysis, we have developed a better understanding of how mutations in AdhE affect ethanol production in the engineered homoethanologen strain. We identify a set of approximately interchangeable AdhE mutations (G544D, T597K, T597I, and T605I), whose function is to disrupt the activity of the alcohol dehydrogenase (ADH) domain of AdhE. This reduces NADH-linked ADH activity, which dramatically increases ethanol tolerance and changes the overall stoichiometry of acetaldehyde to ethanol conversion. Furthermore, our improved understanding of the function of these AdhE mutations calls into question a proposed feature of AdhE enzymes known as substrate channeling—direct transfer of acetaldehyde between the two domains of the AdhE enzyme. This improved the understanding of the role of AdhE mutations in T. saccharolyticum and provides deeper insights into the function of the unique ethanol production pathway in this organism. IMPORTANCE Many anaerobic bacteria maintain redox equilibrium by producing reduced organic compounds such as ethanol. The final two steps of ethanol production are mediated by a bifunctional enzyme, AdhE, and this enzyme is a frequent target of mutations in strains engineered for increased ethanol production. Paradoxically, these mutations increase ethanol production by eliminating the activity of one domain of the AdhE enzyme (the ADH domain). This provides additional support for a redox-imbalance theory of alcohol tolerance, which challenges the prevailing hypothesis that alcohol tolerance is associated with cell membrane effects.

59 BASIC BIOLOGICAL SCIENCES↗

DOE OSTI2025

Contact patterns in wild pigs ( Sus scrofa ) from GPS tracking reveal spatial and temporal dynamics of social behaviour

Wild pig ( Sus scrofa Linnaeus, 1758) social behaviour affects disease transmission and landscape-level population management. Recent research has incorporated analysis of social structure to better understand the risk of disease transmission in wild pigs, although the relationship between overall social structure of wild pigs remains unclear. Here, we seek to improve understanding of the spatial and temporal dynamics of wild pig social structure and contact rates to better inform management strategies. Using GPS tracking data, we measured home range overlap, and estimated contact rates of wild pigs at four study sites in the southern USA to identify pairwise social associations (i.e., contacts) based on synchronous movement. Contact rate was strongly associated with home range overlap, but exhibited substantial variation, especially at moderate levels of home range overlap. We found that female–female dyads had higher contact rates and longer duration phases of social association compared to female–male and male–male dyads. We found male–male dyads tended to experience social associations farther from their home range centers than female–female or female–male dyads. Social associations between wild pig dyads are highly dynamic in their spatial and temporal structure. Further, dyads with strong social associations still experience substantial time apart. Our findings highlight the challenges of predicting spatial and social associations in wild pig social pairs due to their dynamic social structure over space and time.

McIlraith, Jack R.↗

DOE OSTI2024

Quantifying the Role of Ocean Dynamics in SST Variability across GCMs and Observations

Abstract Midlatitude SSTs forced by mesoscale oceanic processes can affect the large-scale atmosphere, pointing to the ocean’s crucial role outside the tropics. Previous studies have shown oceanic mesoscale processes’ effect on global and regional climate variability. This study quantifies the local contribution of ocean dynamics to mixed-layer temperature across the globe by directly estimating the ocean heat flux divergence resolved by state-of-the-art ocean reanalysis, eddy-resolving, and eddy-parameterized versions of two U.S. national climate models and indirectly from air–sea flux satellite-based estimates. Our results show that the eddy-resolving climate simulations resolve mixed-layer temperature variances that are larger and closer to those inferred from observations than both their eddy-parameterized counterparts and ECCO over much of the extratropics. The observations and the eddy-resolving models indicate a more significant role of ocean dynamics in the mixed-layer temperature variability than the surface fluxes over most extratropics compared to their eddy-parameterized versions. A frequency domain analysis shows that the better-resolved ocean mesoscale and thermal gradients enhance the variance over a time scale from 2 months to 30 years. Results show agreement in the ocean’s contribution among satellite-based estimates, ocean reanalysis products, and ocean eddy-resolving simulations. At the same time, differences emerge for ECCO and the eddy-parameterized models, suggesting that surface fluxes account for a larger fraction of the mixed-layer temperature variability in most of the extratropics.

Siqueira, L.↗

DOE OSTI2026

Investigating the Impacts of Aqueous-Phase Processing on Organic Aerosol Chemical Climatology Using ARM and ASR Observations

This project improved understanding of how atmospheric aerosol particles form and evolve, with a focus on the role of water-driven (aqueous-phase) chemical reactions in the atmosphere. These processes occur in clouds, fog, and humid air and can significantly change the composition and properties of airborne particles, known as aerosols, which influence air quality and climate. By combining field measurements, laboratory experiments, and advanced analytical techniques, the project identified key chemical signatures that allow scientists to distinguish particles formed through aqueous processes from those formed in the gas phase. Observations from multiple environments, including wildfire smoke, urban regions, and cloud-influenced areas, show that aqueous chemistry is an important pathway for particle formation and aging. The project also developed new measurement approaches using uncrewed aerial systems (UAS) to capture how aerosol composition varies with altitude, providing critical insights into how particles interact with clouds. In addition, new data analysis frameworks were created to better interpret long-term aerosol measurements and improve characterization of particle sources and transformations. These results have been integrated into a global database of aerosol measurements and used to support atmospheric modeling efforts. Overall, the project provides important tools and knowledge to improve predictions of how aerosols affect climate and air quality, particularly through their interactions with radiation and clouds.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

NASA NTRS1980

The structure and evolution of X-ray clusters of galaxies

Einstein Observatory observations of the structures of nearby X-ray clusters of galaxies are discussed in relation to dynamic cluster evolution. Examples of Virgo-type clusters, in which cool and hot gas associated with cluster members are presented and variations in surface brightness profile and the location of the cluster center are used to classify the observed clusters. The types of clusters observed are interpreted in terms of dynamic cluster evolution, with Virgo-type clusters with broad, highly clumped emission and low velocity dispersion representing early evolutionary stages, clusters containing a cD galaxy formed as the cluster evolves, and clusters with dominant galaxies and Coma-type clusters representing an equilibrium stage. X-ray emission from poor clusters of galaxies is also considered, and similarities between the presumably collisionally formed cD galaxies in rich and poor clusters are noted. Finally, observations of distant clusters are discussed, and it is noted that their analysis will lead to a better determination of the evolutionary sequence.

Jones, C.↗

NASA NTRS1984

Spectral scan of Orion A and IRC+10216 from 72 to 91 GHz

The spectra of the Orion KL molecular cloud and the envelope of the carbon star IRC+10216 are surveyed at 1 MHz resolution over the interval 72.2-91.1 GHz to a sensitivity usually better than 0.1 K. Multitransition analysis of several molecular species is presented which gives information on the physical conditions and chemical abundance in the Orion KL region. The excitation conditions and relative abundances in the IRC+10216 envelope are surveyed. It is stressed that the low detection rate of molecular lines in this object does not necessarily imply a poorer chemistry compared with that in interstellar clouds, but is partly a reflection of low abundances and unsatisfied excitation requirements.

Johansson, L. E. B.↗

NASA NTRS1989

Software reuse issues affecting AdaNET

The AdaNet program is reviewing its long-term goals and strategies. A significant concern is whether current AdaNet plans adequately address the major strategic issues of software reuse technology. The major reuse issues of providing AdaNet services that should be addressed as part of future AdaNet development are identified and reviewed. Before significant development proceeds, a plan should be developed to resolve the aforementioned issues. This plan should also specify a detailed approach to develop AdaNet. A three phased strategy is recommended. The first phase would consist of requirements analysis and produce an AdaNet system requirements specification. It would consider the requirements of AdaNet in terms of mission needs, commercial realities, and administrative policies affecting development, and the experience of AdaNet and other projects promoting the transfer software engineering technology. Specifically, requirements analysis would be performed to better understand the requirements for AdaNet functions. The second phase would provide a detailed design of the system. The AdaNet should be designed with emphasis on the use of existing technology readily available to the AdaNet program. A number of reuse products are available upon which AdaNet could be based. This would significantly reduce the risk and cost of providing an AdaNet system. Once a design was developed, implementation would proceed in the third phase.

Mcbride, John G.↗

NASA NTRS1991

Contraction ratio effects in a generic sidewall compression scramjet inlet - A computational and experimental investigation

Computed and experimental data on a generic three-dimensional sidewall compression scramjet inlet with a leading edge sweep of 45 degrees at Mach 20 are presented. A three-dimensional Navier-Stokes code was adapted to perform preliminary parametric studies leading to the present configuration. Following the design phase, the code was then employed as an analysis tool to provide a better understanding of the flow field and the experimental static and pitot pressure data. The model possessed 240 static pressure orifices distributed on the forebody plane, sidewalls, and cowl and was tested in the 31 Inch Mach 10 facility at the NASA Langley Research Center. Pitot rakes were employed to map the entrance and exit planes. The contraction ratio was observed to have a dominant effect on the inlet shock structure and performance; these effects are the emphasis of the present report. In addition to pressure measurements, oil flows were used for further visualization and comparison with computation.

Holland, Scott D.↗

NASA NTRS1992

Turbulent spectra, fluxes, stability and growth of the mixed layer in the boundary layer of Mars

Spectra of wind and temperature from high frequency measurements in the atmospheric surface layer of Mars are presented for the first time. Heat and momentum fluxes, and stability are calculated for early spring from estimates of the surface temperature and mean Viking Lander 2 temperature and wind at 44 degrees N, using similarity theory. This study provides the first estimates of (1) the height of the mixed layer, (2) spectra of wind and temperature, (3) the validity of similarity theories on Mars, and (4) bounds of effective measuring height and surface roughness. It confirms and extends the universiality of model wind spectra. Finally and more important, we provide the ability to estimate and determine the self-consistency of Martian atmospheric mixed layer fluxes, stability and heights on a diurnal and annual basis. This can be used to initialize and validate the various models, which previously could only be compared with each other or the efforts of Sutton, Leovy and Tillman: these were restricted in season and limited by the results from the surface temperature model available at that time. Analysis of additional data can better estimate z(sub 0) values directly from the measurements and provide the parameters necessary to calculate the vertical profiles of wind and temperature on a daily, seasonal and annual basis.

Tillman, James E.↗

NASA NTRS1992

Reynolds number and cowl position effects for a generic sidewall compression scramjet inlet at Mach 10 - A computational and experimental investigation

Reynolds number and cowl position effects on the internal shock structure and the resulting performance of a generic three-dimensional sidewall compression scramjet inlet with a leading edge sweep of 45 degrees at Mach 10 have been examined both computationally and experimentally. Prior to the experiment, a three-dimensional Navier-Stokes code was adapted to perform preliminary parametric studies leading to the design of the present configuration. Following this design phase, the code was then utilized as an analysis tool to provide a better understanding of the flow field and the experimental static pressure data for the final experimental configuration. The wind tunnel model possessed 240 static pressure orifices distributed on the forebody plane, sidewalls, and cowl and was tested in the NASA Langley 31 Inch Mach 10 Tunnel.

Holland, Scott D.↗

NASA NTRS1993

Prediction of gas-liquid two-phase flow regime in microgravity

An attempt is made to predict gas-liquid two-phase flow regime in a pipe in a microgravity environment through scaling analysis based on dominant physical mechanisms. Simple inlet geometry is adopted in the analysis to see the effect of inlet configuration on flow regime transitions. Comparison of the prediction with the existing experimental data shows good agreement, though more work is required to better define some physical parameters. The analysis clarifies much of the physics involved in this problem and can be applied to other configurations.

Lee, Jinho↗

NASA NTRS1993

Use of global positioning system measurements to determine geocentric coordinates and variations in Earth orientation

Geocentric tracking station coordinates and short-period Earth-orientation variations can be measured with Global Positioning System (GPS) measurements. Unless calibrated, geocentric coordinate errors and changes in Earth orientation can lead to significant deep-space tracking errors. Ground-based GPS estimates of daily and subdaily changes in Earth orientation presently show centimeter-level precision. Comparison between GPS-estimated Earth-rotation variations, which are the differences between Universal Time 1 and Universal Coordinated Time (UT1-UTC), and those calculated from ocean tide models suggests that observed subdaily variations in Earth rotation are dominated by oceanic tidal effects. Preliminary GPS estimates for the geocenter location (from a 3-week experiment) agree with independent satellite laser-ranging estimates to better than 10 cm. Covariance analysis predicts that temporal resolution of GPS estimates for Earth orientation and geocenter improves significantly when data collected from low Earth-orbiting satellites as well as from ground sites are combined. The low Earth GPS tracking data enhance the accuracy and resolution for measuring high-frequency global geodynamical signals over time scales of less than 1 day.

R P Malla↗

NASA NTRS1995

Functional relationships among monitoring performance: Subjective report of thought process and compromising states of awareness

A biocybernetic system for use in adaptive automation was evaluated using EEG indices based on the beta, alpha, and theta bandwidths. Subjects performed a compensatory tracking task while their EEG was recorded and one of three engagement indices was derived: beta/(alpha + theta), beta/alpha, or 1/alpha. The task was switched between manual and automatic modes as a function of the subjects' level of engagement and whether they were under a positive or negative feedback condition. It was hypothesized that negative feedback would produce more switches between manual and automatic modes, and that the beta/(alpha + theta) index would produce the strongest effect. The results confirmed these hypotheses. There were no systematic changes in these effects over three 16-minute trials. Tracking performance was found to be better under negative feedback. An analysis of the different EEG bands under positive and negative feedback in manual and automatic modes found more beta power in the positive feedback/manual condition and less in the positive feedback/automatic condition. The opposite effect was observed for alpha and theta power. The implications of biocybernetic systems for adaptive automation are discussed.

Freeman, Frederick↗

NASA NTRS1999

Improving Reanalyses Using TRMM and SSM/I-Derived Precipitation and Total Precipitable Water Observations

Global reanalyses currently contain significant errors in the primary fields of the hydrological cycle such as precipitation, evaporation, moisture, and the related cloud fields, especially in the tropics. The Data Assimilation Office (DAO) at the NASA Goddard Space Flight Center has been exploring the use of rainfall and total precipitable water (TPW) observations from the Tropical Rainfall Measuring Mission (TRMM) Microwave Imager (TMI) and the Special Sensor Microwave/ Imager (SSM/I) instruments to improve these fields in reanalyses. The DAO has developed a "1+1"D procedure to assimilate 6-hr averaged rainfall and TPW into the Goddard Earth Observing System (GEOS) Data Assimilation System (DAS). The algorithm is based on a 6-hr time integration of a column version of the GEOS DAS. The "1+1" designation refers to one spatial dimension plus one temporal dimension. The scheme minimizes the least-square differences between the satellite-retrieved rain rates and those produced by the column model over the 6-hr analysis window. The control variables are analysis increments of moisture within the Incremental Analysis Update (IAU) framework of the GEOS DAS. This 1+1D scheme, in its generalization to four dimensions, is related to the standard 4D variational assimilation but differs in its choice of the control variable. Instead of estimating the initial condition at the beginning of the assimilation cycle, it estimates the constant IAU forcing applied over a 6-hr assimilation cycle. In doing so, it imposes the forecast model as a weak constraint in a manner similar to the variational continuous assimilation techniques. We present results from an experiment in which the observed rain rate and TPW are assumed to be "perfect". They show that assimilating the TMI and SSM/I-derived surface precipitation and TPW observations improves not only the precipitation and moisture fields but also key climate parameters directly linked to convective activities such as clouds, the outgoing longwave radiation, and the large-scale circulation in the tropics. In particular, assimilating these data types reduce the state-dependent systematic errors in the assimilated products. The improved analysis also leads to a better short-range forecast, but the impact is modest compared with improvements in the time-averaged fields. These results suggest that, in the presence of biases and other errors of the forecast model, it is possible to improve the time-averaged "climate content" in the assimilated data without comparable improvements in the short-range forecast skill. Results of this experiment provide a useful benchmark for evaluating error covariance models for optimal use of these data types.

Hou, Arthur Y.↗

NASA NTRS2000

GRACE Mission Design: Impact of Uncertainties in Disturbance Environment and Satellite Force Models

The Gravity Recovery and Climate Experiment (GRACE) primary mission will be performed by making measurements of the inter-satellite range change between two co-planar, low altitude, near-polar orbiting satellites. Understanding the uncertainties in the disturbance environment, particularly the aerodynamic drag and torques, is critical in several mission areas. These include an accurate estimate of the spacecraft orbital lifetime, evaluation of spacecraft attitude control requirements, and estimation of the orbital maintenance maneuver frequency necessitated by differences in the drag forces acting on both satellites. The FREEMOL simulation software has been developed and utilized to analyze and suggest design modifications to the GRACE spacecraft. Aerodynamic accommodation bounding analyses were performed and worst-case envelopes were obtained for the aerodynamic torques and the differential ballistic coefficients between the leading and trailing GRACE spacecraft. These analyses demonstrate how spacecraft aerodynamic design and analysis can benefit from a better understanding of spacecraft surface accommodation properties, and the implications for mission design constraints such as formation spacing control.

Mazanek, Daniel D.↗

NASA NTRS2000

Aerothermal Analysis and Design of the Gravity Recovery and Climate Experiment (GRACE) Spacecraft

The Gravity Recovery and Climate Experiment (GRACE) primary mission will be performed by making measurements of the inter-satellite range change between two co-planar, low altitude near-polar orbiting satellites. Understanding the uncertainties in the disturbance environment, particularly the aerodynamic drag and torques, is critical in several mission areas. These include an accurate estimate of the spacecraft orbital lifetime, evaluation of spacecraft attitude control requirements, and estimation of the orbital maintenance maneuver frequency necessitated by differences in the drag forces acting on both satellites. The FREEMOL simulation software has been developed and utilized to analyze and suggest design modifications to the GRACE spacecraft. Aerodynamic accommodation bounding analyses were performed and worst-case envelopes were obtained for the aerodynamic torques and the differential ballistic coefficients between the leading and trailing GRACE spacecraft. These analyses demonstrate how spacecraft aerodynamic design and analysis can benefit from a better understanding of spacecraft surface accommodation properties, and the implications for mission design constraints such as formation spacing control.

Mazanek, Daniel D.↗

NASA NTRS1992

Reynolds Number and Cowl Position Effects for a Generic Sidewall Compression Scramjet Inlet at Mach 10: A Computational and Experimental Investigation

Holland, Scott D.↗

NASA NTRS2004

Sensitivity of a Cloud-Resolving Model to the Bulk and Explicit Bin Microphysical Schemes

A cloud-resolving model is used to study sensitivities of two different microphysical schemes, one is the bulk type, and the other is an explicit bin scheme, in simulating a mid-latitude squall line case. Simulations using different microphysical schemes are compared with each other and also with the observations. Both the bulk and bin models reproduce the general features during the developing and mature stage of the system. The leading convective zone, the trailing stratiform region, the horizontal wind flow patterns, pressure perturbation associated with the storm dynamics, and the cool pool in front of the system all agree well with the observations. Both the observations and the bulk scheme simulation serve as validations for the newly incorporated bin scheme. However, it is also shown that the bulk and bin simulations have distinct differences, most notably in the stratiform region. Weak convective cells exist in the stratiform region in the bulk simulation, but not in the bin simulation. These weak convective cells in the stratiform region are remnants of the previous stronger convections at the leading edge of the system. The bin simulation, on the other hand, has a horizontally homogeneous stratiform rain structure, which agrees better with the observations. Further analysis of the downdraft core strength, the potential temperature perturbation, and the evaporative cooling rate shows that the differences between the bulk and bin models are due mainly to the stronger low-level evaporative cooling simulated in the bulk model. Further quantitative analysis and sensitivity tests for this case using both the bulk and bin models will be presented in the talk.

Tao, Wei-Kuo↗