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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 181 records · Page 10
All sourcesNASA NTRSDOE OSTI
NASA NTRS2003

Comparison of mode estimation methods and application in molecular clock analysis

BACKGROUND: Distributions of time estimates in molecular clock studies are sometimes skewed or contain outliers. In those cases, the mode is a better estimator of the overall time of divergence than the mean or median. However, different methods are available for estimating the mode. We compared these methods in simulations to determine their strengths and weaknesses and further assessed their performance when applied to real data sets from a molecular clock study. RESULTS: We found that the half-range mode and robust parametric mode methods have a lower bias than other mode methods under a diversity of conditions. However, the half-range mode suffers from a relatively high variance and the robust parametric mode is more susceptible to bias by outliers. We determined that bootstrapping reduces the variance of both mode estimators. Application of the different methods to real data sets yielded results that were concordant with the simulations. CONCLUSION: Because the half-range mode is a simple and fast method, and produced less bias overall in our simulations, we recommend the bootstrapped version of it as a general-purpose mode estimator and suggest a bootstrap method for obtaining the standard error and 95% confidence interval of the mode.

Evolution, Molecular↗
DOE OSTI2017

Practical Weak-lensing Shear Measurement with Metacalibration

Metacalibration is a recently introduced method to accurately measure weak gravitational lensing shear using only the available imaging data, without need for prior information about galaxy properties or calibration from simulations. The method involves distorting the image with a small known shear, and calculating the response of a shear estimator to that applied shear. The method was shown to be accurate in moderate-sized simulations with galaxy images that had relatively high signal-to-noise ratios, and without significant selection effects. In this work we introduce a formalism to correct for both shear response and selection biases. We also observe that for images with relatively low signal-to-noise ratios, the correlated noise that arises during the metacalibration process results in significant bias, for which we develop a simple empirical correction. To test this formalism, we created large image simulations based on both parametric models and real galaxy images, including tests with realistic point-spread functions. We varied the point-spread function ellipticity at the five-percent level. In each simulation we applied a small few-percent shear to the galaxy images. We introduced additional challenges that arise in real data, such as detection thresholds, stellar contamination, and missing data. We applied cuts on the measured galaxy properties to induce significant selection effects. Using our formalism, we recovered the input shear with an accuracy better than a part in a thousand in all cases.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2022

Single reader between-cases AUC estimator with nested data

The area under the receiver operating characteristic curve (AUC) is widely used in evaluating diagnostic performance for many clinical tasks. It is still challenging to evaluate the reading performance of distinguishing between positive and negative regions of interest (ROIs) in the nested-data problem, where multiple ROIs are nested within the cases. To address this issue, we identify two kinds of AUC estimators, within-cases AUC and between-cases AUC. We focus on the between-cases AUC estimator, since our main research interest is in patient-level diagnostic performance rather than location-level performance (the ability to separate ROIs with and without disease within each patient). Another reason is that as the case number increases, the number of between-cases paired ROIs is much larger than the number of within-cases ROIs. We provide estimators for the variance of the between-cases AUC and for the covariance when there are two readers. We derive and prove the above estimators’ theoretical values based on a simulation model and characterize their behavior using Monte Carlo simulation results. We also provide a real-data example. Moreover, we connect the distribution-based simulation model with the simulation model based on the linear mixed-effect model, which helps better understand the sources of variation in the simulated dataset.

Health Care Sciences & Services↗
NASA NTRS1985

Results of an observing system simulation experiment based on the proposed Windsat instrument

Two fraternal twin experiments were conducted as part of this study. A data impact experiment using real data (runs 1 and 2) was conducted to assess the impact that rawin wind observations have on both a 5-day assimilation and a single 5-day forecast generated at the end of each assimilation. An observing system simulation experiment (OSSE) using simulated observations (runs 3, 4, and 5) was conducted in order to first calibrate the OSSE results and second to use this calibration to estimate the 'real world' impact from the contribution of global 3-dimensional wind profiles generated from a space-based lidar system known as Windsat. Each of the three runs in the seond experiment were also 5-day assimilation runs with a 5-day forecast initialized from the last 6-hour update cycle of the assimilation. The data impact study revealed a consistent positive impact when rawin winds were added back into an otherwise complete FGGE data set. Both the 6-hour and 5-day forecasts were improved at all levels, in both hemispheres, and for both the wind and the geopotential height fields. Similar results were obtained from the two parallel simulation runs, 3 and 4. Together with the results from runs 1 and 2, calibration coefficients were generated so as to 'correct' the results determined from the addition of Windsat winds (run 5). The Windsat simulation showed a positive improvement in all cases studied. Even though only the tropics were enhanced with these wind observations, hemispheric rms errors were decreased in both the assimilation and 5-day forecast. The 6-hour forecasts of zonal wind from the assimilation run were improved by as much as 50 pct. on the average, and the single forecast showed an average improvement of near 30 pct. Even though these calibrated values are considered too optimistic, the skill of the forecast generated from this run extended the useful forecast period by 18-24 hours.

Arnold, Charles P., Jr.↗
NASA NTRS1999

Backus Effect on a Perpendicular Errors in Harmonic Models of Real vs. Synthetic Data

Measurements of geomagnetic scalar intensity on a thin spherical shell alone are not enough to separate internal from external source fields; moreover, such scalar data are not enough for accurate modeling of the vector field from internal sources because of unmodeled fields and small data errors. Spherical harmonic models of the geomagnetic potential fitted to scalar data alone therefore suffer from well-understood Backus effect and perpendicular errors. Curiously, errors in some models of simulated 'data' are very much less than those in models of real data. We analyze select Magsat vector and scalar measurements separately to illustrate Backus effect and perpendicular errors in models of real scalar data. By using a model to synthesize 'data' at the observation points, and by adding various types of 'noise', we illustrate such errors in models of synthetic 'data'. Perpendicular errors prove quite sensitive to the maximum degree in the spherical harmonic expansion of the potential field model fitted to the scalar data. Small errors in models of synthetic 'data' are found to be an artifact of matched truncation levels. For example, consider scalar synthetic 'data' computed from a degree 14 model. A degree 14 model fitted to such synthetic 'data' yields negligible error, but amplifies 4 nT (rmss) added noise into a 60 nT error (rmss); however, a degree 12 model fitted to the noisy 'data' suffers a 492 nT error (rmms through degree 12). Geomagnetic measurements remain unaware of model truncation, so the small errors indicated by some simulations cannot be realized in practice. Errors in models fitted to scalar data alone approach 1000 nT (rmss) and several thousand nT (maximum).

Voorhies, C. V.↗
DOE OSTI2021

Health-Related Quality of Life Outcomes in Head and Neck Cancer: Results From a Prospective, Real-World Data Study With Brazilian Patients Treated With Intensity Modulated Radiation Therapy, Conformal and Conventional Radiation Techniques

To compare global health-related quality of life (HRQoL) and overall survival (OS) in patients with head and neck cancer treated with intensity modulated radiation therapy (IMRT), conformal radiation therapy (3DCRT) or conventional radiation therapy (2DRT).

62 RADIOLOGY AND NUCLEAR MEDICINE↗
DOE OSTI2025

The real-time data processing and acquisition system for Project 8 Phase II

In Phase II of the Project 8 neutrino mass experiment, electrons from the decays of tritium or 83m Kr are detected via their ≈26 GHz cyclotron radiation while contained within a circular waveguide. The signal from a given electron is characterized as a brief chirp, lasting ≲10 ms and changing in frequency by ≲1 MHz/ms. To detect these signals, the Project 8 collaboration developed a Data Acquisition (DAQ) system tailored to the signal properties. The DAQ is responsible for simultaneously selecting up to three 100 MHz-wide frequency windows to study, detect, and trigger on likely signals from different electron kinetic energies, and for writing the relevant data to disk. Finally, we describe the Phase II DAQ system in detail and address how the system was used for data-taking operations.

Data acquisition↗
DOE OSTI2015

SU-F-207-09: Evaluating the Dosimetric Accuracy of Extended Field-Of-View CT Reconstructions Using Clinical Data with Real Patient Geometries

Purpose: To determine the accuracy of dose calculations performed with CT images reconstructed using extended field of view (FOV) algorithms. Methods: In this study we selected 6 radiotherapy patients (3 head and neck & 3 chest/pelvis) whose body circumferences extended past the 50 cm scan FOV in the treatment planning CT. Images acquired on a Siemens Sensation Open scanner, were reconstructed using the standard FOV (sFOV) and two different extended FOV algorithms, eFOV and HDFOV. A physician and dosimetrist identified the radiation target, critical organs, and external patient contour. A benchmark CT was created for each patient, consisting of an average of the 3 CT reconstructions with a density override applied to regions containing truncation artifacts, and was used to create an optimal radiation treatment plan. The plan was copied onto each reconstruction without density override and dose was recalculated. Results: The native sFOV dose calculations had the largest deviation from the benchmark (0.4 – 6.0%). Both the HDFOV and eFOV calculations showed improvement over the sFOV. For patients with a smooth patient contour, the HDFOV calculation had the least deviation from the benchmark (0.1–0.5%) compared to eFOV (0.4–1.8%). In cases with large amounts of tissue and irregular skin folds, the eFOV deviated the least from the benchmark (0.2–0.6%) compared to HDFOV (1.3–1.8%). It was observed that the eFOV scan has large image artifact in air with an average HU of −600 compared to the ideal of −1000. In these cases, the artifact in air appears to attenuate the dose and compensate for the missing tissue density. The HDFOV demonstrated minimal artifact in air. Conclusion: Both eFOV and HDFOV provide improved dose calculation accuracy. The HDFOV reconstruction provides a clearer patient border than the eFOV allowing for well-defined density overrides to be applied with minimal air artifact. This research was supported by Siemens Medical Solutions.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2020

Impact of simultaneous activities on frequency fluctuations — comprehensive analyses based on the real measurement data from FNET/GridEye

Simultaneous human activities such as the Super Bowl game would cause certain impacts on frequency fluctuations in power systems. With the help of FNET/GridEye measurements, this work aims to give comprehensive analyses on the frequency fluctuations during Super Bowl LIV held on Feb. 2, 2020, so as to better understand several phenomena caused by simultaneous activities and help system operation and control. First, recent developments of FNET/GridEye are introduced briefly. Second, the frequency fluctuations of Eastern Interconnection (EI), western electricity coordinating council (WECC), and electric reliability council of Texas (ERCOT) power systems during Super Bowl LIV are analyzed. Third, frequency fluctuations of Super Bowl Sunday and ordinary Sundays in 2020 are compared. Finally, the differences of frequency fluctuations among different years during the Super Bowl and their change trend are also given. Furthermore, several possible explanations including the simultaneity of electricity consumption at the beginning of commercial breaks and the halftime show, the increasing usage of the Internet, and the increasing size of TV screens are illustrated in detail in this work.

24 POWER TRANSMISSION AND DISTRIBUTION↗
DOE OSTI2021

Real-Time Data Acquisition and Processing System for MHz Repetition Rate Image Sensors

An electro-optic detector is one of the diagnostic setups used in particle accelerators. It employs an electro-optic crystal to encode the longitudinal beam charge profile in the spectrum of a light pulse. The charge distribution is then reconstructed using data captured by a fast spectrometer. The measurement repetition rate should match or exceed the machine bunching frequency, which is often in the range of several MHz. A high-speed optical line detector (HOLD) is a linear camera designed for easy integration with scientific experiments. The use of modern FPGA circuits helps in the efficient collection and processing of data. The solution is based on Xilinx 7-Series FPGA circuits and implements a custom latency-optimized architecture utilizing the AXI4 family of interfaces. HOLD is one of the fastest line cameras in the world. Thanks to its hardware architecture and a powerful KALYPSO sensor from KIT, it outperforms the fastest comparable commercial devices.

MicroTCA↗