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At least 181 records · Page 10

Passport to Knowledge: Electronic Field Trips to Scientific Frontiers Via Interactive TV and the Internet

The Passport to Knowledge project delivered its initial 3-year NASA supported activity in December 1994 and January 1995. Live from Antarctica was an integrated, multimedia activity, including four one hour-long video programs, all with live components as well as taped segments, together with an extensive online element containing interactive as well as background information, and the printed Live from Antarctica Teacher's Guide, suggesting hands-on, in-class activities.

Haines-Stiles, Geoff↗

Geoscience Laser Altimeter System (GLAS): Final Test Report of DM LHP TV Testing

The Demonstration Model (DM) Loop Heat Pipe (LHP) was tested at Goddard Space Flight Center (GSFC) during September and October, 1999. The LHP system was placed in the Dynavac 36 in. chamber in Building 4. The test lasted for about 6 weeks. The LHP was built, designed, and manufactured at Dynatherm Corporation, Inc. In Hunt Valley, MD according to GSFC specifications. The purpose of the test was to evaluate the performance of a propylene LHP for the Geoscience Laser Altimetry System (GLAS) instrument application.

Baker, Charles↗

Geoscience Laser Altimeter System (GLAS) Final Test Report of DM LHP TV Testing

Two loop heat pipes (LHPs) are to be used for thermal control of the Geoscience Laser Altimeter System (GLAS), planned for flight in 2001. One LHP will be used to transport 100 W from a laser to the radiator, the other will transport 210 W from electronic boxes to the radiator. In order to verify the LHP design for the GLAS application, an LHP Development Model has been fabricated, and ambient and thermal vacuum tested. Two aluminum blocks of 15 kg and 30 kg, respectively, were attached to the LHP to simulate the thermal masses connected to the heat sources. A 20 W starter heater was installed on the evaporator to aid the loop startup. A new concept to thermally couple the vapor and liquid line was also incorporated in the LHP design. Such a thermal coupling would reduce the power requirement on the compensation chamber in order to maintain the loop set point temperature. To avoid freezing of the liquid in the condenser during cold cases, propylene was selected as the working fluid. The LHP was tested under reflux mode and with adverse elevation. Tests conducted included start-up, power cycle, steady state and transient operation during hot and cold cases, and heater power requirements for the set point temperature control of the LHP. Test results showed very successful operation of the LHP under all conditions. The 20 W starter heater proved necessary in order to start the loop when a large thermal mass was attached to the evaporator. The thermal coupling between the liquid line and the vapor line significantly reduced the heater power required for loop temperature control, which was less than 5 watts in all cases, including a cold radiator. The test also demonstrated successful operation with a propylene working fluid, with successful startups with condenser temperatures as low as 100 C. Furthermore, the test demonstrated accurate control of the loop operating temperature within +/- 0.2 C, and a successful shutdown of the loop during the survival mode of operation.

Baker, Charles↗

ASCA Observations of the Dwarf Novae SS Cyg and VW Hyi And Observations of the Precessing Disk Cataclysmic Variable TV Col

The observations for both SS Cyg and VW Hyi were to be scheduled as Targets of Opportunity jointly with other satellites. The VW Hyi observation was obtained jointly with EUVE during a superoutburst. The XTE data were initially processed, revealing no detection. However, the XTE team improved the instrumental background model and distributed it in July 1998. A further improvement was made in August 1999. The improved models allow a better background subtraction, thereby detecting previously un-detected sources.

Schlegel, E.↗

International Space Station (ISS) External Television (TV) Camera Shutdown Investigation

In the early morning of January 15, 2006, the Stardust Sample Return Capsule (SRC) successfully delivered its precious cargo of cometary particles to the awaiting recovery team at the Utah Test and Training Range (UTTR). As the SRC entered at 12.8 km/s, the fastest manmade object to traverse the atmosphere, a team of researchers imaged the event aboard the NASA DC-8 airborne observatory. At SRC entry, the airplane was at an altitude of 11.9 km positioned within 6.4 km of the prescribed, preferred target view location. The incoming SRC was first acquired approximately 18 seconds (s) after atmospheric interface and tracked for approximately 60 s, an observation period that is roughly centered in time around predicted peak heating.

Kichak, Robert↗

Tulane virus protease as a structural surrogate for inhibitor screening of human norovirus proteases

Human norovirus (HuNoV) is a significant cause of gastroenteritis worldwide, affecting people of all age groups. There are currently no vaccines or drugs available, leaving susceptible populations vulnerable to severe or protracted illness. A HuNoV cultivation system is pivotal for screening norovirus antivirals. While the human intestinal enteroid cultivation system allows robust replication of multiple HuNoV strains, it presents technical and cost barriers. Tulane virus (TV), a surrogate for HuNoV, replicates well in monkey kidney cell lines and is closely related to norovirus in cellular biology. Here, we determined the structures of TV protease (TV-Pro) alone and in complex with rupintrivir, a picornavirus inhibitor that also inhibits HuNoV proteases (HuNoV-Pro). Our data validate TV as an efficient surrogate system for rapid screening of HuNoV protease inhibitors. The TV protease structure exhibits significant backbone similarity to the GI.1 HuNoV protease in the substrate-binding domain, with the BII-CII loop in an open conformation stabilized by hydrogen bonds as present in the GI.1 protease. Structural differences in the S2 pocket and two amino acid changes in the S4 pocket result in slightly altered P2 and P4 substrate and inhibitor conformations. Despite these differences, we confirm previous findings that the TV protease can cleave the GI.1 and GII HuNoV polyprotein substrates with high and moderate efficiency, respectively. We found that rupintrivir efficiently inhibits TV protease in vitro and inhibits TV replication in cell culture with similar efficacy in combination with P-glycoprotein efflux pump inhibitors. We conclude that TV is a valuable surrogate for HuNoV protease inhibitor screening and outline strategies to improve its compatibility as such.

crystal structures↗

Development and test of video systems for airborne surveillance of oil spills

Five video systems - potentially useful for airborne surveillance of oil spills - were developed, flight tested, and evaluated. The systems are: (1) conventional black and white TV, (2) conventional TV with false color, (3) differential TV, (4) prototype Lunar Surface TV, and (5) field sequential TV. Wavelength and polarization filtering were utilized in all systems. Greatly enhanced detection of oil spills, relative to that possible with the unaided eye, was achieved. The most practical video system is a conventional TV camera with silicon-diode-array image tube, filtered with a Corning 7-54 filter and a polarizer oriented with its principal axis in the horizontal direction. Best contrast between oil and water was achieved when winds and sea states were low. The minimum detectable oil film thickness was about 0.1 micrometer.

Millard, J. P.↗

Payload operation television system

The Payload Operation Television System is a high performance closed-circuit TV system designed to determine the feasibility of using TV to augment purely visual monitoring of operations, and to establish optimum system design of an operating unit which can ultimately be used to assist the operator of a remotely manipulated space-borne cargo loading device. The TV system assembled on this program is intended for laboratory experimentation which would develop operational techniques and lead to the design of space-borne TV equipment whose purpose would be to assist the astronaut-operator aboard a space station to load payload components. The equipment consists principally of a good quality TV camera capable of high resolving power; a TV monitor; a sync generator for driving camera and monitor; and two pan/tilt units which are remotely controlled by the operator.

Source record↗

Space shuttle/mesoscale lightning experiment

A payload integration plan (PIP) is now being developed with Johnson Space Center integration personnel which covers management, structural thermal, electrical power/avionics, training, ground operations, safety requirements, etc., in support of this experiment. If a Shuttle flight can be identified, researchers hope to conduct the experiment in the late summer or fall of 1985. Some preliminary TV lightning data has been collected by Shuttle crews on 41D and 51D and researchers are doing an analysis of it. Additional flights will be conducted to obtain data on Mesoscale Lightning Observations. Researchers will continue to study how to improve the data collection using the onboard TV cameras. By more interaction with the crews who have used the TV camera to obtain TV of lightning, they are planning to optimize the crew time and have better TV camera operations management to produce more useful data. As the crews are better trained in the use of the gain control settings and/or camera iris operations, the quality of the TV data will be improved.

Vaughan, O. H., Jr.↗

Elliptical-P cells in the avian perilymphatic interface of the Tegmentum vasculosum

Elliptical cells (E-P) are present at the perilymphatic interface lumen (PIL) of the lagena. The E-P cells often separate from the tegmentum vasculosum (TV) and have touching processes that form a monolayer between the K+ rich perilymph and the Na+ rich endolymph, similar to the mammalian Reissner's membrane. We examined the TV of chicks (Gallus domesticus) and quantitated the expression of anti-S100 alphaalphabetabeta and S100 beta. There was a 30% increase of S100 beta saturation in the light cells facing the PIL when compared to other TV light cells. We show that: (1) the dimer anti- S100 alphaalphabetabeta and the monomer anti-S100 beta are expressed preferentially in the light cells and the E-P cells of TV; (2) expression of S100 beta is higher in light cells facing the PIL than in adjacent cells; (3) the expression of the dimer S100 alphaalphabetabeta and monomer S100 beta overlaps in most inner ear cell types, including the cells of the TV, most S100 alphaalphabetabeta positive cells express S 100 beta, but S100 beta positive cells do not always express S100 alphaalphabetabeta; and (4) the S100 beta expression in light cells, the abundant Na+-K+ ATPase on dark cells of the TV, and previously demonstrated co-localization of S100 beta/GABA in sensory cells suggest that S100 beta could have, in the inner ear, a dual neurotrophic-ionic modulating function.

NASA Discipline Neuroscience↗

Closed-Form Approximation of the Total Variation Proximal Operator

Total variation (TV) is a widely used function for regularizing imaging inverse problems that is particularly appropriate for images whose underlying structure is piecewise constant. TV regularized optimization problems are typically solved using proximal methods, but the way in which they are applied is constrained by the absence of a closed-form expression for the proximal operator of the TV function. A closed-form approximation of the TV proximal operator has previously been proposed, but its accuracy was not theoretically explored in detail. Here, we address this gap by making several new theoretical contributions, proving that the approximation leads to a proximal operator of some convex function, it is equivalent to a gradient descent step on a smoothed version of TV, and that its error can be fully characterized and controlled with its scaling parameter. We experimentally validate our theoretical results on image denoising and sparse-view computed tomography (CT) image reconstruction.

97 MATHEMATICS AND COMPUTING↗

Payload operation television system

The TV system assembled is intended for laboratory experimentation which would develop operational techniques and lead to the design of space-borne TV equipment whose purpose would be to assist the astronaut-operator aboard a space station to load payload components. The TV system assembled for this program is a black and white, monocular, high performance system. The equipment consists principally of a good quality TV camera capable of high resolving power; a TV monitor; a sync generator for driving camera and monitor; and two pan/tilt units which are remotely controlled by the operator. One pan/tilt unit provides control of the pointing of the camera, the other similarly controls the position of a simulated payload.

Source record↗

The Influence of Loss of Visual Cues on Pilot Performance During the Final Approach and Landing Phase of a Remotely Piloted Vehicle Mission

Remotely piloted research vehicles (RPRVS) are currently being flown from fixed-base control centers, and visual information is supplied to the remote pilot by a TV camera mounted in the vehicle. In these circumstances, the possibility of a TV failure or an interruption in the downlink to the pilot must be considered. To determine the influence of loss of TV information on pilot performance during the final approach and landing phase of a mission, an experiment was conducted in which pilots were asked to fly a fixed-base simulation of a Piper PA-30 aircraft with loss of TV information occurring at altitudes of 15.24, 30.48, and 45.72 m (50, 100, and 150 ft). For this experiment, a specially designed display configuration was presented to four pilots in accordance with a Latin square design. Initial results indicate that pilots could not ensure successful landings from altitudes exceeding 15.24 m (.50 ft) without the visual cues supplied by the TV picture.

Howard, James C.↗

A Trichomonas vaginalis C2-XYPPX-repeat protein with a structured C2 domain displaying dampened flexibility upon binding calcium

C2 domains are ubiquitous membrane-binding modules of ∼130 residues in eukaryotes that are often associated with proteins involved in membrane trafficking and lipid modification. The genome of Trichomonas vaginalis, the most common, non-viral, sexually transmitted human pathogen, encodes eight genes that contain a N-terminal C2 module linked to a XYPPX-repeat domain of more than four XYPPX repeats (C2-XYPPX). While the function of the XYPPX-repeat domain remains unknown, its multiple association with C2 domains in T. vaginalis suggests it is important. Here, the C2 domain from one of these C2-XYPPX-repeat proteins, Tv-C2-1, was structurally and physically characterized using X-ray crystallography and NMR spectroscopy. The crystal structure for Tv-C2-1 shows that this domain shares a fold common to all C2 domains, a compact Greek-key motif composed of eight anti-parallel β-strands in the type-2 topology. An NMR chemical shift perturbation study with Ca 2+ showed that Tv-C2-1 bound two Ca 2+ atoms primarily via two loops (loop-1 and loop-3) on the predicted calcium binding face of the protein with K d s of 58.0 ± 0.1 μM and 232 ± 6 μM. Estimations of the overall rotational correlation time, τ c , in the apo (11.1 ns) and Ca 2+ -bound (9.2 ns) state suggests the protein becomes more compact upon Ca 2+ binding, consistent with a decrease in dynamics in loop-3 and marginally in loop-1 suggested by amide 15 N heteronuclear steady-state { 1 H}- 15 N NOEs. Showing Tv-C2-1 binds calcium and adopts a compact Greek-key motif structure, two primary features of C2 domains, suggests understanding the function of the XYPPX-repeat domain may be warranted.

NMR spectroscopy↗

𝑇-invariance violation in neutrino oscillations and matter effects

We investigate the impact of matter effects on 𝑇 (time-reversal)-odd observables, making use of the quantum-mechanical formalism of neutrino-flavor evolution. We attempt to be comprehensive and pedagogical. Matter-induced 𝑇-invariance violation (TV) is qualitatively different from, and more subtle than, matter-induced 𝐶⁢𝑃 (charge-parity)-invariance violation. If the matter distribution is symmetric relative to the neutrino production and detection points, matter effects will not introduce any new TV. However, if there is intrinsic TV, matter effects can modify the size of the 𝑇-odd observable. On the other hand, if the matter distribution is not symmetric, there is genuine matter-induced TV. For Earth-bound long-baseline oscillation experiments, these effects are small. This remains true for unrealistically-asymmetric matter potentials (for example, we investigate the effects of “hollowing out” 50% of the DUNE neutrino trajectory). More broadly, we explore consequences, or lack thereof, of asymmetric matter potentials on oscillation probabilities. While fascinating in their own right, 𝑇-odd observables are currently of limited practical use, due in no small part to a dearth of intense, well-characterized, high-energy electron-neutrino beams. Further in the future, however, intense, high-energy muon storage rings might become available and allow for realistic studies of 𝑇-invariance in neutrino oscillations.

CP violation↗

Rapid Optimization of Total Variation with Applications in Imaging, Additive Manufacturing, and Qualification

Total Variation optimization penalizes the gradient of a control variable or state. While this work focuses on image processing in particular, it has also found applications in inverse problems and topology optimization. In image processing, the goal is to maintain faithfulness to the original image while denoising and/or deblurring. Additionally, bilevel optimization over the spatially varying regularization weights can illuminate interfaces such as damage regions and other anomalies. We will address two fundamental challenges with TV-optimization: (i) the typical slow convergence of existing TV-optimization methods, and (ii) the selection of spatially varying TV parameters to promote interface detection. Additionally, we will apply such techniques to image data collected in additive manufacturing. In said context, stochasticity in build events induces flaws in the manufactured piece, compromising the integrity of said part. There is a critical need for in-situ monitoring to spot anomalies once they form, and in this setting we apply our total variation and hyperparameter solvers. We will develop a customized algorithm based on for extreme-scale TV-optimization that achieves super-linear or quadratic-convergence, a critical property for real-time, image-by-image analysis. A worst-case outcome is a preprocessing step that enhances image quality in-situ, specifically for out-of-focus and noisy images.

36 MATERIALS SCIENCE↗

Protection Against Graph-Based False Data Injection Attacks on Power Systems

Graph signal processing (GSP) has emerged as a powerful tool for practical network applications, including power system monitoring. By representing power system voltages as smooth graph signals, recent research has focused on developing GSP-based methods for state estimation, attack detection, and topology identification. Included, efficient methods have been developed for detecting false data injection (FDI) attacks, which until now were perceived as non-smooth with respect to the graph Laplacian matrix. Consequently, these methods may not be effective against smooth FDI attacks. In this paper, we propose a graph FDI (GFDI) attack that minimizes the Laplacian-based graph total variation (TV) under practical constraints. In addition, we develop a low-complexity algorithm that solves the non-convex GDFI attack optimization problem using ell_1-norm relaxation, the projected gradient descent (PGD) algorithm, and the alternating direction method of multipliers (ADMM). We then propose a protection scheme that identifies the minimal set of measurements necessary to constrain the GFDI output to high graph TV, thereby enabling its detection by existing GSP-based detectors. Our numerical simulations on the IEEE-57 bus test case reveal the potential threat posed by well-designed GSP-based FDI attacks. Moreover, we demonstrate that integrating the proposed protection design with GSP-based detection can lead to significant hardware cost savings compared to previous designs of protection methods against FDI attacks.

Morgenstern, Gal↗