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At least 181 records · Page 10

Molecular Mechanisms of Circadian Regulation During Spaceflight

Disruption of the regular environmental circadian cues in addition to stringent and demanding operational schedules are two main factors that undoubtedly impact sleep patterns and vigilant performance in the astronaut crews during spaceflight. Most research is focused on the behavioral aspects of the risk of circadian desynchronization, characterized by fatigue and health and performance decrement. A common countermeasure for circadian re-entrainment utilizes blue-green light to entrain the circadian clock and mitigate this risk. However, an effective countermeasure targeting the photoreceptor system requires that the basic circadian molecular machinery remains intact during spaceflight. The molecular clock consists of sets of proteins that perform different functions within the clock machinery: circadian oscillators (genes whose expression levels cycle during the day, keep the pass of cellular time and regulate downstream effector genes), the effector or output genes (those which impact the physiology of the tissue or organism), and the input genes (responsible for sensing the environmental cues that allow circadian entrainment). The main environmental cue is light. As opposed to the known photoreceptors (rods and cones), the non-visual light stimulus is received by a subset of the population of retinal ganglion cells called intrinsically photosensitive retinal ganglion cells (ipRGC) that express melanopsin (opsin 4 -Opn4-) as the photoreceptor. We hypothesize that spaceflight may affect ipRGC and melanopsin expression, which may be a contributing cause of circadian disruption during spaceflight. To answer this question, eyes from albino Balb/cJ mice aboard STS-133 were collected for histological analysis and gene expression profiling of the retina at 1 and 7 days after landing. Both vivarium and AEM (animal enclosure module) mice were used as ground controls. Opn4 expression was analyzed by real time RT/qPCR and retinal sections were stained for Opn4 immunofluorescence. Opn4 was decreased (abrogated in one case) in retinas that concurrently showed higher evidence of oxidative stress. We propose that oxidative stress can lead to a decrease in melanopsin expression, likely via ipRGC loss or impairment, and thus, it can be a contributing factor to circadian disruption during spaceflight. Countermeasures contemplating the use of light should therefore be complemented with melanopsin expression maintenance and/or reduction in oxidative stress.

Zanello, Susana↗

Molecular Mechanisms of Circadian Regulation During Spaceflight

The physiology of both vertebrates and invertebrates follows internal rhythms coordinated in phase with the 24-hour daily light cycle. This circadian clock is governed by a central pacemaker, the suprachiasmatic nucleus (SCN) in the brain. However, peripheral circadian clocks or oscillators have been identified in most tissues. How the central and peripheral oscillators are synchronized is still being elucidated. Light is the main environmental cue that entrains the circadian clock. Under the absence of a light stimulus, the clock continues its oscillation in a free-running condition. In general, three functional compartments of the circadian clock are defined. The vertebrate retina contains endogenous clocks that control many aspects of retinal physiology, including retinal sensitivity to light, neurohormone synthesis (melatonin and dopamine), rod disk shedding, signalling pathways and gene expression. Neurons with putative local circadian rhythm generation are found among all the major neuron populations in the mammalian retina. In the mouse, clock genes and function are more localized to the inner retinal and ganglion cell layers. The photoreceptor, however, secrete melatonin which may still serve a an important circadian signal. The reception and transmission of the non-visual photic stimulus resides in a small subpopulation (1-3%) or retinal ganglion cells (RGC) that express the pigment melanopsin (Opn4) and are called intrisically photoreceptive RGC (ipRGC). Melanopsin peak absorption is at 420 nm and all the axons of the ipRGC reach the SCN. A common countermeasure for circadian re-entrainment utilizes blue-green light to entrain the circadian clock and mitigate the risk of fatigue and health and performance decrement due to circadian rhythm disruption. However, an effective countermeasure targeting the photoreceptor system requires that the basic circadian molecular machinery remains intact during spaceflight. We hypothesize that spaceflight may affect ipRGC and melanopsin expression, which may be a contributing cause of circadian disruption during spaceflight.

Zanello, S. B.↗

Gas Sloshing and Radio Galaxy Dynamics in the Core of the 3C 449 Group

We present results from a 140 ks Chandra/ACIS-S observation of the hot gas around the canonical FR I radio galaxy 3C 449. An earlier, shorter 30 ks Chandra observation of the group gas showed an unusual entropy distribution and a surface brightness edge in the gas that could be a strong shock around the inner radio lobes. In our deeper data we find no evidence for a temperature increase inside of the brightness edge, but a temperature decrease across part of the edge. This suggests that the edge is a "sloshing" cold front due to a merger within the last 1.3-1.6 Gyr. Both the northern and southern inner jets are bent slightly to the west in projection as they enter their respective lobes, suggesting that the sloshing core is moving to the east. The straight inner jet flares at approximately the position where it crosses the contact edge, suggesting that the jet is entraining and thermalizing some of the hot gas as it crosses the edge.We also detect filaments of X-ray emission around the southern inner radio jet and lobe which we attribute to low entropy entrained gas. The lobe flaring and gas entrainment were originally predicted in simulations of Loken et al. and are confirmed in our deep observation.

Lal, Dharam V.↗

Do We Already have Samples of CERES H Chondrite Haliites and the CERES-HEBE Link

We investigate the hypothesis that halite grains in the brecciated H chondrites Zag and Monahans originate from Ceres. Evidence includes mineralogy of the halites consistent with formation on a large, carbonaceous, aqueously active body close to the H chondrite parent body >4 Ga ago. Evidence also includes orbital simularities between 1 Ceres and the purported H chondrite parent body (HPB) 6 Hebe, possibly facilitating a gentle transfer between the bodies. Halite grains in the Monahans and Zag Hchondrites are exogenous to the H chondrite parent body and were transported to the HPB >4 Ga ago. Examination of minerals and carboanceous materials entrained within the halites shows that the halite parent body (HaPB) is consistent with a carbonaceous body [1]. It is probably a large body due to the variety of entrained carbonaceous materials which probably accreted from multiple sources. The halite grains contain intact, HaPB-origin, ancient fluid inclusions indicating that transfer between the HaPB and the HPB was a gentle process resulting in a ΔT of <25 degC. Ejection from the HaPB may have been via cryovolcanic processes similar to those on modern-day Enceladus, which have been interpreted to include halite from spectroscopic observations. The ΔTmax to preserve the brinebearing halite restricts the impact velocity to the HPB at less than ≈350-700 m/s, depending upon the fraction of kinetic energy used heat the sample. [2-6]. Therefore the HaPB and HPB must have shared nearby orbits at the time of the HaPB-HPB transfer. Evidence presented elsewhere indicates asteroid 6 Hebe is a favored candidate for the HPB based on reflectance spectrum similarity with H chondrites and dynamical arguments [7,8]. The modern orbits of Ceres and Hebe are reasonably similar, with aphelion/perihelion of Ceres and Hebe of 2.99/2.55 and 2.91/1.94 AU, respectively. Initial calculations indicate an approximate mean infall velocity of 1.20 to 1.38 km/s. While higher than 350- 700 m/s, the orbits may have been more favorable >4 Ga ago. Additional dynamical factors need to be investigated. A combination of factors suggests Ceres as the HaPB. It is a carbonaceous body with suggestions of past aqueous activity [9], which is consistent with the mineral species found in H chondrite halites. Ceres is also a large body capable of accreting the range of carbonaceous materials noted [5]. It is relatively near to purported HPB Hebe, which is required to preserve halite fluid inclusions. The above evidence defines a hypothesized scenario featuring ejection of halite grains from Ceres onto Hebe. Halite was then entrained in H-chondrite near-surface breccias and ejected from Hebe for transport to Earth.

Fries, Marc D.↗

The Tropical Subseasonal Variability Simulated in the NASA GISS General Circulation Model

The tropical subseasonal variability simulated by the Goddard Institute for Space Studies general circulation model, Model E2, is examined. Several versions of Model E2 were developed with changes to the convective parameterization in order to improve the simulation of the Madden-Julian oscillation (MJO). When the convective scheme is modified to have a greater fractional entrainment rate, Model E2 is able to simulate MJO-like disturbances with proper spatial and temporal scales. Increasing the rate of rain reevaporation has additional positive impacts on the simulated MJO. The improvement in MJO simulation comes at the cost of increased biases in the mean state, consistent in structure and amplitude with those found in other GCMs when tuned to have a stronger MJO. By reinitializing a relatively poor-MJO version with restart files from a relatively better-MJO version, a series of 30-day integrations is constructed to examine the impacts of the parameterization changes on the organization of tropical convection. The poor-MJO version with smaller entrainment rate has a tendency to allow convection to be activated over a broader area and to reduce the contrast between dry and wet regimes so that tropical convection becomes less organized. Besides the MJO, the number of tropical-cyclone-like vortices simulated by the model is also affected by changes in the convection scheme. The model simulates a smaller number of such storms globally with a larger entrainment rate, while the number increases significantly with a greater rain reevaporation rate.

Kim, Daehyun↗

Impacts of Solar-Absorbing Aerosol Layers on the Transition of Stratocumulus to Trade Cumulus Clouds

The effects of an initially overlying layer of solar-absorbing aerosol on the transition of stratocumulus to trade cumulus clouds are examined using large-eddy simulations. For lightly drizzling cloud the transition is generally hastened, resulting mainly from increased cloud droplet number concentration (Nc) induced by entrained aerosol. The increased Nc slows sedimentation of cloud droplets and shortens their relaxation time for diffusional growth, both of which accelerate entrainment of overlying air and thereby stratocumulus breakup. However, the decrease in albedo from cloud breakup is more than offset by redistributing cloud water over a greater number of droplets, such that the diurnal-average shortwave forcing at the top of the atmosphere is negative. The negative radiative forcing is enhanced by sizable longwave contributions, which result from the greater cloud breakup and a reduced boundary layer height associated with aerosol heating. A perturbation of moisture instead of aerosol aloft leads to a greater liquid water path and a more gradual transition. Adding absorbing aerosol to that atmosphere results in substantial reductions in liquid water path (LWP) and cloud cover that lead to positive short-wave and negative longwave forcings on average canceling each other. Only for heavily drizzling clouds is the breakup delayed, as inhibition of precipitation overcomes cloud water loss from enhanced entrainment. Considering these simulations as an imperfect proxy for biomass burning plumes influencing Namibian stratocumulus, we expect regional indirect plus semi-direct forcings to be substantially negative to negligible at the top of the atmosphere, with its magnitude sensitive to background and perturbation properties.

Zhou, Xiaoli↗

Preliminary Evaluation of the Simplified Higher Order Closure (SHOC) in the NASA Goddard Earth Observing System (GEOS)

Here we evaluate alternative planetary boundary layer (PBL) schemes in the NASA Goddard Earth Observing System (GEOS) model. The model currently calculates turbulent diffusivities with a local Richardson number-based scheme for stable layers, and a K-profile scheme with surface- and cloud-driven plumes based on Lock et al. (2000) for unstable layers. In this study, these are replaced with the TKE-based Simplified Higher Order Closure (SHOC). SHOC combines a 1.5-order turbulence closure with a double-Gaussian PDF serving as a subgrid condensation scheme. The new diffusivity calculations are paired with two new shallow mass flux schemes. First, the University of Washington shallow cumulus scheme of Park and Bretherton (2009), a buoyancy-sorting entraining-detraining bulk plume with overshooting entrainment and a TKE/CIN-based closure. Second, an Eddy Diffusivity Mass Flux (EDMF) scheme based on the multiple plume model of Suselj et al. (2013) with stochastic lateral entrainment. Global climatologies of low level temperature, humidity, and wind are evaluated against MERRA-2 and ERA-Interim reanalyses, and significant reductions in bias are seen with both mass flux schemes. The diurnal cycle over the continental United States is evaluated using MERRA-2 and an in situ network of surface Lidar profilers.

Arnold, Nathan↗

Modeling of Initial Detonation-mode Acceleration in Pulsed Plasma and Magnetoplasmadynamic Thrusters

Gas-fed electromagnetic pulsed plasma accelerators operate by discharging electrical energy into a gas, subsequently ionizing and electromagnetically accelerating propellant. Many efforts to model pulsed accelerators have assumed that the discharge is either short and completely transient, accelerating the gas like a shock by entraining it in a moving current sheet, or that the discharge is relatively long, establishing a stable quasi-steady current distribution through which plasma flows and is accelerated. This idealization encounters problems when thrusters possess some qualities associated with both short and long-pulse-length thrusters. To capture all possible scenarios, a model is presented based upon the idea that all pulsed plasma accelerators first form an accelerating current sheet (detonation mode accelerator) and then, depending upon the pulse length and the manner in which the plasma reaches the thruster exit, it can transition to the quasi-steady acceleration configuration (deflagration mode accelerator). In the present work the detonation mode is investigated, varying controllable parameters to determine their effects on the plasma acceleration process. The primary driver affecting current sheet acceleration is the amount of gas that the plasma encounters and entrains as it moves towards the thruster exit. The amount of neutral gas the plasma entrains affects the time it takes the plasma to reach the end of the accelerator and changes the corresponding electrical discharge parameters at the end of detonation mode acceleration.

Polzin, Kurt A.↗

Impact of a Cold Pool Parameterization on the Diurnal Cycle and Intraseasonal Variability in the GEOS AGCM

A gradual transition from shallow to deep convection may be important both to the continental diurnal cycle of precipitation and to the tropical Madden-Julian Oscillation. However, many existing convection parameterizations transition too readily, with corresponding diurnal and intraseasonal biases. High entrainment rates can be used to delay deep convection, but typically produce mean state biases; this is the "entrainment dilemma." Cold pools and sub-grid organization offer a potential solution to this dilemma, and recent work shows parameterized cold pools can effectively modulate deep convection, with improvements to the diurnal cycle and intraseasonal variability. Here we investigate the effects of a simple prognostic cold pool scheme coupled to the Grell-Freitas convection parameterization, in a set of global simulations with the NASA GEOS model. Air detrained from parameterized downdrafts is maintained in vertically resolved cold pools, which evolve with simplified dynamics. We test several options for cold pool feedbacks on convection, including modifications to deep convective entrainment rates, convective source air properties, and thermodynamic profiles, based on the level of cold pool activity. Cold pool impacts on the diurnal cycle are evaluated against TRMM, and moisture and moist static energy budgets are used to understand changes in tropical intraseasonal variability. Preliminary results show delays in the diurnal cycle of precipitation.

Arnold, Nathan↗

A Methodology for Estimating the Energy and Moisture Budget of the Convective Boundary Layer Using Continuous Ground-Based Infrared Spectrometer Observations

Land-atmosphere interactions play a critical role in both the atmospheric water and energy cycles. Changes in soil moisture and vegetation alter the partitioning of surface water and energy fluxes, influencing diurnal evolution of the planetary boundary layer (PBL). The mixing diagram framework has proven useful in understanding the evolution of the heat and moisture budget within the convective boundary layer (CBL). We demonstrate that observations from the Department of Energy Atmospheric Radiation Measurement (ARM) Southern Great Plains (SGP) site provide all of the needed inputs needed for the mixing diagram framework, allowing us to quantify the impact from the surface fluxes, advection, radiative heating, encroachment, and entrainment on the evolution of the CBL. Profiles of temperature and humidity retrieved from the ground-based infrared spectrometer (called the Atmospheric Emitted Radiance Interferometer, or AERI) are a critical component in this analysis. Large eddy simulation results demonstrate that mean mixed-layer values derived are shown to be critical to close the energy and moisture budgets. A novel approach demonstrated here is the use of network of AERIs and Doppler lidars to quantify the advective fluxes of heat and moisture. The framework enables the estimation of the entrainment fluxes as a residual, providing a way to observe the entrainment fluxes without using multiple lidar systems. Finally, the high temporal resolution of the AERI observations enable the morning, midday, and afternoon evolution of the CBL to be quantified. This work provides a new way to use observations in this framework to evaluate weather and climate models.

Boundary layer↗

Constraints on Cumulus Parameterization from Simulations of Observed MJO Events

Two recent activities offer an opportunity to test general circulation model (GCM) convection and its interaction with large-scale dynamics for observed Madden-Julian oscillation (MJO) events. This study evaluates the sensitivity of the Goddard Institute for Space Studies (GISS) GCM to entrainment, rain evaporation, downdrafts, and cold pools. Single Column Model versions that restrict weakly entraining convection produce the most realistic dependence of convection depth on column water vapor (CWV) during the Atmospheric Radiation Measurement MJO Investigation Experiment at Gan Island. Differences among models are primarily at intermediate CWV where the transition from shallow to deeper convection occurs. GCM 20-day hindcasts during the Year of Tropical Convection that best capture the shallow–deep transition also produce strong MJOs, with significant predictability compared to Tropical Rainfall Measuring Mission data. The dry anomaly east of the disturbance on hindcast day 1 is a good predictor of MJO onset and evolution. Initial CWV there is near the shallow–deep transition point, implicating premature onset of deep convection as a predictor of a poor MJO simulation. Convection weakly moistens the dry region in good MJO simulations in the first week; weakening of large-scale subsidence over this time may also affect MJO onset. Longwave radiation anomalies are weakest in the worst model version, consistent with previous analyses of cloud/moisture greenhouse enhancement as the primary MJO energy source. The authors’ results suggest that both cloud-/moisture-radiative interactions and convection–moisture sensitivity are required to produce a successful MJO simulation.

Madden-Julian Oscillation↗

General Circulation Models Simulate Negative Liquid Water Path­–Droplet Number Correlations, but Anthropogenic Aerosols Still Increase Simulated Liquid Water Path

General circulation models' (GCMs) estimates of the liquid water path adjustment to anthropogenic aerosol emissions differ in sign from other lines of evidence. This reduces confidence in estimates of the effective radiative forcing of the climate by aerosol–cloud interactions (ERFaci). The discrepancy is thought to stem in part from GCMs' inability to represent the turbulence–microphysics interactions in cloud-top entrainment, a mechanism that leads to a reduction in liquid water in response to an anthropogenic increase in aerosols. In the real atmosphere, enhanced cloud-top entrainment is thought to be the dominant adjustment mechanism for liquid water path, weakening the overall ERFaci. We show that the latest generation of GCMs includes models that produce a negative correlation between the present-day cloud droplet number and liquid water path, a key piece of observational evidence supporting liquid water path reduction by anthropogenic aerosols and one that earlier-generation GCMs could not reproduce. However, even in GCMs with this negative correlation, the increase in anthropogenic aerosols from preindustrial to present-day values still leads to an increase in the simulated liquid water path due to the parameterized precipitation suppression mechanism. This adds to the evidence that correlations in the present-day climate are not necessarily causal. We investigate sources of confounding to explain the noncausal correlation between liquid water path and droplet number. These results are a reminder that assessments of climate parameters based on multiple lines of evidence must carefully consider the complementary strengths of different lines when the lines disagree.

General circulation models↗

Analysis of the Injection of a Heated, Turbulent Jet into a Moving Mainstream, with Emphasis on a Thermal Discharge in a Waterway

An experimental and theoretical investigation was undertaken to study the trajectory and growth of thermal effluents having a range of discharge velocities and temperatures. The discharge of a turbulent effluent into a waterway was mathematically modeled as a submerged jet injection process by using an integral method which accounts for natural fluid mechanisms such as turbulence, entrainment, buoyancy, and heat transfer. The analytical results are supported by experimental data and demonstrate the usefulness of the theory for estimating the location and size of the effluent with respect to the discharge point. The capability of predicting jet flow properties, as well as two- and three-dimensional jet paths, was enhanced by obtaining the jet cross-sectional area during the solution of the conservation equations. Realistic estimates of temperature in the effluent were acquired by accounting for heat losses in the jet flow due to forced convection and to entrainment of free-stream fluid into the jet.

Campbell, J. F.↗

Analysis of the injection of a heated turbulent jet into a cross flow

The development of a theoretical model is investigated of the incompressible jet injection process. The discharge of a turbulent jet into a cross flow was mathematically modeled by using an integral method which accounts for natural fluid mechanisms such as turbulence, entrainment, buoyancy, and heat transfer. The analytical results are supported by experimental data and demonstrate the usefulness of the theory for estimating the trajectory and flow properties of the jet for a variety of injection conditions. The capability of predicting jet flow properties, as well as two- and three-dimensional jet paths, was enhanced by obtaining the jet cross-sectional area during the solution of the conservation equations. Realistic estimates of temperature in the jet fluid were acquired by accounting for heat losses in the jet flow due to forced convection and to entrainment of free-stream fluid into the jet.

Campbell, J. F.↗

A Method for Calculating the Induced Pressure Distribution Associated with a Jet in a Crossflow

A model is presented which can be used to study the loss of lift during hovering and horizontal flight of the VTOL aircraft. The model numerically predicts the pressure distribution induced by a round, turbulent, unheated, subsonic jet exhausting normally through a flat plate into a subsonic crossflow. The complete model assumes that the predominant features of the flow are jet entrainment and a pair of contrarotating vortices which form downstream of the jet. Experimentally determined vortex properties and a reasonable assumption concerning jet entrainment were used. Potential flow considerations were used except in the wake region, where a simple method for approximating the pressure distribution was suggested. The calculated pressure distribution, lift, and pitching moments on the flat plate are presented for a jet to crossflow velocity ratio of 8 and were compared with experimental results. A computer program is given which was used to calculate the pressure distribution across the flat plate.

Dietz, W. E., Jr.↗

A theoretical investigation of over-wing-blowing aerodynamics

A theoretical method is established for determining the aerodynamic characteristics of over-wing-blowing configurations. The method accounts for both jet entrainment and jet interaction effects because of the differences in freestream and jet dynamic pressures and Mach numbers. The predicted lift increments agree well with available data. It is shown that the lift is underpredicted with entrainment effect alone when the jet is close to the wing surface.

Lan, C. E.↗

A nonlinear theory for airfoils with trailing-edge jet flap

A nonlinear procedure for computing the pressure distribution on an airfoil with a trailing edge jet flap is described. The method is not restricted to thin airfoils or shallow jet-deflection angles. Correlation with experiment indicates that the characteristics of the pressure distribution are predicted by the theory, but the effect of entrainment is overpredicted with the entrainment coefficient used.

Barger, R. L.↗

Combustion effects on film cooling

The effects of: (1) a reactive environment on film cooling effectiveness, and (2) film cooling on rocket engine performance were determined experimentally in a rocket thrust chamber assembly operating with hydrogen and oxygen propellants at 300 psi chamber pressure. Tests were conducted using hydrogen, helium, and nitrogen film coolants in an instrumented, thin walled, steel thrust chamber. The film cooling, performance loss, and heat transfer coefficient data were correlated with the ALRC entrainment film cooling model which relates film coolant effectiveness and mixture ratio at the wall to the amount of mainstream gases entrained with the film coolant in a mixing layer. In addition, a comprehensive thermal analysis computer program, HOCOOL, was prepared from previously existing ALRC computer programs and analytical techniques.

Rousar, D. C.↗