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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 181 records · Page 10
All sourcesNASA NTRSDOE OSTI
DOE OSTI2024

An interaction network in the polymerase active site is a prerequisite for Watson-Crick base pairing in Pol γ

The replication accuracy of DNA polymerase gamma (Pol γ) is essential for mitochondrial genome integrity. Mutation of human Pol γ arginine-853 has been linked to neurological diseases. Although not a catalytic residue, Pol γ arginine-853 mutants are void of polymerase activity. To identify the structural basis for the disease, we determined a crystal structure of the Pol γ mutant ternary complex with correct incoming nucleotide 2'-deoxycytidine 5'-triphosphate (dCTP). Opposite to the wild type that undergoes open-to-closed conformational changes when bound to a correct nucleotide that is essential for forming a catalytically competent active site, the mutant complex failed to undergo the conformational change, and the dCTP did not base pair with its Watson-Crick complementary templating residue. Our studies revealed that arginine-853 coordinates an interaction network that aligns the 3'-end of primer and dCTP with the catalytic residues. Disruption of the network precludes the formation of Watson-Crick base pairing and closing of the active site, resulting in an inactive polymerase.

59 BASIC BIOLOGICAL SCIENCES↗
NASA NTRS1994

Channel to energy calibration results for the BATSE large area detectors

Continuum 16 channel spectra obtained from in flight data are used to identify and correct for nonlinearities in the channel-to-energy conversion algorithm for the BATSE large area detectors. The Crab Nebula spectra obtained by the BATSE earth occultation technique are used to characterize any nonlinearities inherent in the low energy channel bin widths on a detector by detector basis. The bin widths are optimized to remove distortions from observed gamma ray spectra. The recalibrated bin edges are used in an analysis of Crab Pulsar data to verify the improvements in the calibration.

Pendleton, Geoffrey N.↗
NASA NTRS2008

Photo-Double Ionization: Threshold Law and Low-Energy Behavior

The threshold law for photoejection of two electrons from atoms (PDI) is derived from a modification of the Coulomb-dipole (C-D) theory. The C-D theory applies to two-electron ejection from negative ions (photo-double detachment:PDD). The modification consists of correctly accounting for the fact that in PDI that the two escaping electrons see a Coulomb field, asymptotically no matter what their relative distances from the residual ion are. We find in the contralinear spherically symmetric model that the analytic threshold law Q(E),i. e. the yield of residual ions, to be Qf(E)approaches E + CwE(sup gamma(w)) + CE(sup 5/4)sin[1/2 ln(E + theta)]/ln(E). The first and third terms are beyond the Wannier law. Our threshold law can only be rigorously justified for residual energies less than or equal to 10(exp -3) eV. Nevertheless in the present experimental range (0.1 - 4 eV), the form, even without the second term, can be fitted to experimental results of PDI for He, Li, and Be, in contrast to the Wannier law which has a larger deviation from the data for Li and Be, for both of which the data show signs of modulation.

Bhatia, Anand↗
NASA NTRS1985

Range fluctuations of high energy muons passing through matter

The information about energy spectrum of sea level muons at high energies beyond magnetic spectrographs can be obtained from the underground intensity measurements if the fluctuations problems are solved. The correction factor R for the range fluctuations of high energy muons were calculated by analytical method of Zatsepin, where most probable energy loss parameter are used. It is shown that by using the R at great depth together with the slope, lambda, of the vertical depth-intensity (D-I) curve in the form of exp(-t/lambda), the spectral index, gamma, in the power law energy spectrum of muons at sea level can be obtained.

Minorikawa, Y.↗
NASA NTRS1978

Role of back stress in the creep behavior of particle strengthened alloys

Recent developments in the interpolation of high-temperature steady-state creep results have introduced the concept that the stress dependence of the creep rate should be in terms of the effective stress referred to as the applied stress minus a back stress. This paper reports on back stresses taken from data on a gamma-prime-strengthened wrought nickel-base superalloy, an oxide dispersion-strengthened ODS nickel-base solid solution alloy, and an ODS nickel-base superalloy. The effect of air versus vacuum environments and the effect of dynamic changes in the strengthening microstructures on the magnitude of the back stress are assessed. The role of modulus normalization and the back stress correction in determining the true creep activation energy are examined. It is shown that the high values of the apparent stress exponent 'n' of the steady-state creep equation can be easily explained through a relationship between n, the true stress exponent of steady-state creep, and the stress which when subtracted from the applied stress results in the effective driving stress acting on the mobile dislocations during creep.

Purushothaman, S.↗
NASA NTRS2019

Analysis of Broad-Lined Type Ic Supernovae From the (Intermediate) Palomar Transient Factory

We study 34 Type Ic supernovae that have broad spectral features (SNe Ic-BL). This is the only SN type found in association with long duration gamma-ray bursts (GRBs).We obtained our photometric data with the Palomar Transient Factory (PTF) and its continuation, the intermediate PTF (iPTF). This is the first large, homogeneous sample of SNe Ic-BL from an untargeted survey. Furthermore, given the high observational cadence of iPTF, most of these SNe Ic-BL were discovered soon after explosion. We present K-corrected Bgriz light curves of these SNe, obtained through photometry on template-subtracted images. We analyzed the shape of the r-band light curves, finding a correlation between the decline parameter delta m15 and the rise parameter delta m-10. We studied the SN colors and, based on g - r, we estimated the host-galaxy extinction for each event. Peak r-band absolute magnitudes have an average of -18:6 +- 0:5 mag. We fit each r-band light curve with that of SN 1998bw (scaled and stretched) to derive the explosion epochs. We computed the bolometric light curves using bolometric corrections, r-band data, and g - r colors. Expansion velocities from Fe ii were obtained by fitting spectral templates of SNe Ic. Bolometric light curves and velocities at peak were fitted using the semianalytic Arnett model to estimate ejecta mass Mej, explosion energy EK and 56Ni mass M(56Ni) for each SN. We find average values of Mej = 4 +- 3 M sun, EK = (7 +- 6) x 1051 erg, and M(56Ni) = 0:31 +- 0:16 M . The parameter distributions were compared to those presented in the literature and are overall in agreement with them. We also estimated the degree of 56Ni mixing using scaling relations derived from hydrodynamical models and we find that all the SNe are strongly mixed. The derived explosion parameters imply that at least 21% of the progenitors of SNe Ic-BL are compatible with massive (>28 M ), possibly single stars, whereas at least 64% might come from less massive stars in close binary systems.

Supernovae↗
DOE OSTI2024

Systematic Effects in Galaxy-Galaxy Lensing with DESI

The Dark Energy Spectroscopic Instrument (DESI) survey will measure spectroscopic redshifts for millions of galaxies across roughly $14,000 \, \mathrm{deg}^2$ of the sky. Cross-correlating targets in the DESI survey with complementary imaging surveys allows us to measure and analyze shear distortions caused by gravitational lensing in unprecedented detail. In this work, we analyze a series of mock catalogs with ray-traced gravitational lensing and increasing sophistication to estimate systematic effects on galaxy-galaxy lensing estimators such as the tangential shear $\gamma_{\mathrm{t}}$ and the excess surface density $\Delta\Sigma$ . We employ mock catalogs tailored to the specific imaging surveys overlapping with the DESI survey: the Dark Energy Survey (DES), the Hyper Suprime-Cam (HSC) survey, and the Kilo-Degree Survey (KiDS). Among others, we find that fiber incompleteness can have significant effects on galaxy-galaxy lensing estimators but can be corrected effectively by up-weighting DESI targets with fibers by the inverse of the fiber assignment probability. Similarly, we show that intrinsic alignment and lens magnification are expected to be statistically significant given the precision forecasted for the DESI year-1 data set. Our study informs several analysis choices for upcoming cross-correlation studies of DESI with DES, HSC, and KiDS.

79 ASTRONOMY AND ASTROPHYSICS↗
NASA NTRS2007

Photo-Double Ionization: Threshold Law and Low-Energy Behavior

The threshold law for photoejection of two electrons from atoms (PDI) is derived from a modification of the Coulomb-dipole (C-D) theory. The C-D theory applies to two-electron ejection from negative ions (photo-double detachment:PDD). The modification consists of correctly accounting for the fact that in PDI that the two escaping electrons see a Coulomb field, asymptotically no matter what their relative distances from the residual ion are. We find in the contralinear spherically symmetric model that the analytic threshold law Q(E), i.e. the yield of residual ions, to be Q Integral of (E) varies as E + (C(sub w) E(sup gamma W)) +CE(sup 5/4) sin [1/2 ln E + phi]/ln(E). The first and third terms are beyond the Wannier law. Our threshold law can only be rigorously justified for residual energies <= 10(exp -3) eV. Nevertheless in the present experimental range (0.1 - 4 eV), the form, even without the second term, can be fitted to experimental results of PDI for He, Li, and Be, in contrast to the Wannier law which has a larger deviation from the data for Li and Be.

Bhatia, A. K.↗
NASA NTRS2009

DNA Repair Defects and Chromosomal Aberrations

Yields of chromosome aberrations were assessed in cells deficient in DNA doublestrand break (DSB) repair, after exposure to acute or to low-dose-rate (0.018 Gy/hr) gamma rays or acute high LET iron nuclei. We studied several cell lines including fibroblasts deficient in ATM (ataxia telangiectasia mutated; product of the gene that is mutated in ataxia telangiectasia patients) or NBS (nibrin; product of the gene mutated in the Nijmegen breakage syndrome), and gliomablastoma cells that are proficient or lacking in DNA-dependent protein kinase (DNA-PK) activity. Chromosomes were analyzed using the fluorescence in situ hybridization (FISH) chromosome painting method in cells at the first division post irradiation, and chromosome aberrations were identified as either simple exchanges (translocations and dicentrics) or complex exchanges (involving >2 breaks in 2 or more chromosomes). Gamma irradiation induced greater yields of both simple and complex exchanges in the DSB repair-defective cells than in the normal cells. The quadratic dose-response terms for both simple and complex chromosome exchanges were significantly higher for the ATM- and NBS-deficient lines than for normal fibroblasts. However, in the NBS cells the linear dose-response term was significantly higher only for simple exchanges. The large increases in the quadratic dose-response terms in these repair-defective cell lines points the importance of the functions of ATM and NBS in chromatin modifications to facilitate correct DSB repair and minimize the formation of aberrations. The differences found between ATM- and NBS-deficient cells at low doses suggest that important questions should with regard to applying observations of radiation sensitivity at high dose to low-dose exposures. For aberrations induced by iron nuclei, regression models preferred purely linear dose responses for simple exchanges and quadratic dose responses for complex exchanges. Relative biological effectiveness (RBE) factors of all of the DNA repair-defective cell lines were smaller than those of normal cells, with the DNA-PK-deficient cells having RBEs near unity. To further investigate the sensitivity differences that were observed in ATM and NBS deficient cells, chromosomal aberrations were analyzed in normal lung fibroblast cells treated with KU-55933 (a specific ATM kinase inhibitor) or Mirin (an Mre11- Rad50-Nbs1 complex inhibitor involved in activation of ATM). We also performed siRNA knockdown of these proteins. Preliminary data indicate that chromosome exchanges increase in cells treated with the specific ATM inhibitor. Possible cytogenetic signatures of acute and low dose-rate gamma irradiation in ATM or nibrin deficient and suppressed cells will be discussed.

Hada, Megumi↗
DOE OSTI2024

CACTI CSAPR2 Taranis Retrievals

Taranis is an end-to-end processing chain for radar data written in Python with C extension for computation performance. Features include: masking for quality control, specific differential phase (Kdp), attenuation correction for reflectivity factor (Z) and differential reflectivity (Zdr) in rain, and additional geophysical retrievals. Retrievals are mostly drawn from literature or open-source software when appropriate, and have been tested, tuned, and modified to work with one another cohesively rather than using isolated off-the-shelf algorithms. Incorporated algorithms include hydrometeor (echo) identification, rain water content, raindrop mass-weighted mean diameter (gamma size distribution assumption), and rainfall rate (QPE). Taranis data sets exist for CSAPR2 PPI, HSRHI, and sector RHI scans. Cartesian-gridded data sets were also produced as well as a near-surface rain rate retrieval. More details can be found in the README.

54 ENVIRONMENTAL SCIENCES↗
NASA NTRS1998

A2111: A z= 0.23 Butcher-Oemler Cluster with a Non-Isothermal Atmosphere and Normal Metallicity

We report results from an x-ray spectral study of the z=0.23 Abell 2111 galaxy cluster using the Advanced Satellite for Astrophysics and Cosmology and the ROSAT Position Sensitive Proportional Counter. By correcting for the energy-dependent point-spread function of the instruments, we have examined the temperature structure of the cluster. The cluster's core within 3 is found to have a temperature of 5.4 +/- 0.5 keV, significantly higher than 2.8 +/-0.7 keV in the surrounding region of r = 3-6. This radially decreasing temperature structure can be parameterized by a polytropic index of gamma less than 1.4. Furthermore, the intracluster medium appears clumpy on scales less than 1. Early studies have revealed that the x-ray centroid of the cluster shifts with spatial scale and the overall optical and x-ray morphology is strongly elongated. These results together suggest that A2111 in undergoing a merger, which is likely responsible for the high fraction of blue galaxies observed in the cluster. We have further measured the abundance of the medium as 0.25 +/- 0.14 solar. This value is similar to those of nearby clusters which do not show a large blue galaxy function, suggesting that star formation in disk galaxies and subsequent loss to the intracluster medium do not drastically alter the average abundance of a cluster since z=0.23.

Wang, Q. Daniel↗
NASA NTRS2004

Unfolding of Proteins: Thermal and Mechanical Unfolding

We have employed a Hamiltonian model based on a self-consistent Gaussian appoximation to examine the unfolding process of proteins in external - both mechanical and thermal - force elds. The motivation was to investigate the unfolding pathways of proteins by including only the essence of the important interactions of the native-state topology. Furthermore, if such a model can indeed correctly predict the physics of protein unfolding, it can complement more computationally expensive simulations and theoretical work. The self-consistent Gaussian approximation by Micheletti et al. has been incorporated in our model to make the model mathematically tractable by signi cantly reducing the computational cost. All thermodynamic properties and pair contact probabilities are calculated by simply evaluating the values of a series of Incomplete Gamma functions in an iterative manner. We have compared our results to previous molecular dynamics simulation and experimental data for the mechanical unfolding of the giant muscle protein Titin (1TIT). Our model, especially in light of its simplicity and excellent agreement with experiment and simulation, demonstrates the basic physical elements necessary to capture the mechanism of protein unfolding in an external force field.

Hur, Joe S.↗
NASA NTRS1992

COMPTEL solar flare observations

COMPTEL as part of a solar target of opportunity campaign observed the sun during the period of high solar activity from 7-15 Jun. 1991. Major flares were observed on 9 and 11 Jun. Although both flares were large GOES events (greater than or = X10), they were not extraordinary in terms of gamma-ray emission. Only the decay phase of the 15 Jun. flare was observed by COMPTEL. We report the preliminary analysis of data from these flares, including the first spectroscopic measurement of solar flare neutrons. The deuterium formation line at 2.223 MeV was present in both events and for at least the 9 Jun. event, was comparable to the flux in the nuclear line region of 4-8 MeV, consistent with Solar-Maximum Mission (SSM) Observations. A clear neutron signal was present in the flare of 9 Jun. with the spectrum extending up to 80 MeV and consistent in time with the emission of gamma-rays, confirming the utility of COMPTEL in measuring the solar neutron flux at low energies. The neutron flux below 100 MeV appears to be lower than that of the 3 Jun. 1982 flare by more than an order of magnitude. The neutron signal of the 11 Jun. event is under study. Severe dead time effects resulting from the intense thermal x-rays require significant corrections to the measured flux which increase the magnitude of the associated systematic uncertainties.

Ryan, J. M.↗
NASA NTRS2004

An Off-Axis Model for GRB 031203

The low luminosity radio emission of the unusually faint GRB 031203 has been argued to support the idea of a class of intrinsically sub-energetic gamma-ray bursts (GRBs), currently comprising two members. While low energy GRBs probably exist, we show that the collective prompt and multiwavelength observations of the afterglow of GRB 031203, do not necessarily require a sub-energetic nature for that event. In fact, the data are more consistent with a typical, powerful GRB seen at an angle of about twice the opening angle of the central jet. The (redshift corrected) peak energy, E(sub p), of GRB 031203 then becomes approximately 2 MeV, similar to many other GRBs.

Ramirez-Ruiz, Enrico↗
NASA NTRS1988

The gamma ray north-south effect

Theoretical calculations are presented that explain the balloon observations by O'Neill et al. (1987) of a strong north-south anisotropy of atmospheric gamma rays over the Southern Hemisphere, and to predict the north-south ratios. It is shown that the gamma rays that originate at the longest distances from the telescopes give the largest north-south ratios. Comparisons are made of the experimental north-south ratios measured on balloons launched from Alice Springs, Australia, and from Palestine, Texas, U.S., and predictions are made for ratios at other geomagnetic latitudes and longitudes. It is pointed out that observers who measure backgrounds for celestial sources may be misled unless they correct for the north-south effect.

White, R. S.↗
NASA NTRS1994

Study of activation data of metal samples from LDEF-1 and Spacelab-2

Gamma-ray spectra obtained from samples flown aboard the Long Duration Exposure Facility have been analyzed to obtain the nuclear species produced in this material by the interaction of this material with protons and neutrons in this material by the interaction of this material with protons and neutrons encountered in its 69 month orbital flight as well as to quantify the specific activity (pCi/kg) of these nuclear species. This quantification requires accurate corrections of efficiency, self-attenuation, and background. Plans have been developed for archival of the spectra in a form readily accessible to the scientific, engineering and technical community engaged in space research and application. Work has been initiated in the process of estimating the flux of activating particles encountered by material at various locations of the spacecraft.

Laird, C. E.↗
NASA NTRS1995

Neutron measurements in near-Earth orbit with COMPTEL

The fast neutron flux in near-Earth orbit has been measured with the COMPTEL instrument on the Compton Gamma Ray Observatory (CGRO). For this measurement one of COMPTEL's seven liquid scintillator modules was used as an uncollimated neutron detector with threshold of 12.8 MeV. The measurements cover a range of 4.8 to 15.5 GV in vertical cutoff rigidity and 3 deg to 177 deg in spacecraft geocenter zenith angle. One of the measurements occurred near the minimum of the deepest Forbush decrease ever observed by ground-level neutron monitors. After correction for solar modulation, the total flux is well fitted by separable functions in rigidity and zenith angle. With the spacecraft pointed near the nadir the flux is consistent with balloon measurements of the atmospheric neutron albedo. The flux varies by about a factor of 4 between the extremes of rigidity and a factor of 2 between the extremes of zenith angle. The effect of the spacecraft mass in shielding the detector from the atmospheric neutron albedo is much more important than its role as a source of additional secondary neutrons. The neutron spectral hardness varies little with rigidity or zenith angle and lies in the range spanned by earlier atmospheric neutron albedo measurements.

Morris, D. J.↗
NASA NTRS2003

Karhunen-Loeve Estimation of the Power Spectrum Parameters from the Angular Distribution of Galaxies in Early Sloan Digital Sky Survey Data

We present measurements of parameters of the three-dimensional power spectrum of galaxy clustering from 222 square degrees of early imaging data in the Sloan Digital Sky Survey (SDSS). The projected galaxy distribution on the sky is expanded over a set of Karhunen-Loeve (KL) eigenfunctions, which optimize the signal-to-noise ratio in our analysis. A maximum likelihood analysis is used to estimate parameters that set the shape and amplitude of the three-dimensional power spectrum of galaxies in the SDSS magnitude-limited sample with r* less than 21. Our best estimates are gamma = 0.188 +/- 0.04 and sigma(sub 8L) = 0.915 +/- 0.06 (statistical errors only), for a flat universe with a cosmological constant. We demonstrate that our measurements contain signal from scales at or beyond the peak of the three-dimensional power spectrum. We discuss how the results scale with systematic uncertainties, like the radial selection function. We find that the central values satisfy the analytically estimated scaling relation. We have also explored the effects of evolutionary corrections, various truncations of the KL basis, seeing, sample size, and limiting magnitude. We find that the impact of most of these uncertainties stay within the 2 sigma uncertainties of our fiducial result.

Szalay, Alexander S.↗