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At least 181 records · Page 10

Genomics-Based Security Protocols: From Plaintext to Cipherprotein

The evolving nature of the internet will require continual advances in authentication and confidentiality protocols. Nature provides some clues as to how this can be accomplished in a distributed manner through molecular biology. Cryptography and molecular biology share certain aspects and operations that allow for a set of unified principles to be applied to problems in either venue. A concept for developing security protocols that can be instantiated at the genomics level is presented. A DNA (Deoxyribonucleic acid) inspired hash code system is presented that utilizes concepts from molecular biology. It is a keyed-Hash Message Authentication Code (HMAC) capable of being used in secure mobile Ad hoc networks. It is targeted for applications without an available public key infrastructure. Mechanics of creating the HMAC are presented as well as a prototype HMAC protocol architecture. Security concepts related to the implementation differences between electronic domain security and genomics domain security are discussed.

Shaw, Harry↗

A Fault-Tolerant Clock Synchronization and Geometry Determination Protocol

A fault-tolerant distributed protocol (algorithm) is presented that achieves optimum timing precision (clock synchronization) among the nodes and, simultaneously, determines the network's geometry (shape) - locations and distances of the nodes relative to each other - in a wireless distributed system. This protocol is based on the assumption of initial coarse synchrony of nodes' local clocks. The proposed solution assumes no prior knowledge of the nodes' locations, the distances between the nodes, or network's geometry, but assumes an ordered geometry where nodes have unique identifiers. This protocol accommodates large variations in the communication latencies among the nodes; thus, it applies equally to both wireless and wired networks.

Malekpour, Mahyar R.↗

Mechanism of Quantum Speedup in Novel Population Transfer Protocol for Binary Optimization Problems

We consider a novel quantum population transfer protocol to solve binary optimization problems that exploits quantum many-body dynamics in the delocalized regime. Hard optimization problems are characterized by energy landscape with a large number of local minima separated by large Hamming distances which scale with the problem size. This landscape gives rise to an interesting computational primitive: given an initial bit-string, we are to produce other bit-strings within certain narrow range of energies around the initial state. We consider a specific model we call "impurity band": a system of n qubits in a transverse field, where a number of bitstrings $M<<2^n$ selected at random are assigned random energies distributed in a narrow window of width $W<<1$ around the mean energy $-n$. We demonstrate the existence of the many-body delocalized regime in this model when the spectrum of the model splits into many-body minibands, and a typical eigenstate wave function is a superposition of peaks centered at a large number of local minima. The typical width of the minibands in energy determines the efficiency of the population transfer protocol. We demonstrate theoretically that the population transfer protocol achieves Grover type speedup in the unstructured impurity band model.

Kechedzhi, Kostyantyn↗

Demand access protocol design and validation with SPIN

In order for distributed systems to communicate reliably engineers standardize on communication rules (or protocols). Unforeseen behavior in communication protocols can push faults up to applications resulting in uncontrollable systems and should not be tolerated. However, while most modern protocols undergo extensive testing, rigorous formal methods, such as model checking,are rarely used due to complexity and massive incomputable state spaces.

Seguí, John S.↗

The Use of the CCSDS Unified Space Data Link Protocol on All Space Links

NASA is actively pursuing the development of data link layer protocols for the human space program with the added intent of infusing the key capabilities of efficient space link security, support for inter-networking, and compatible operational modes with Optical Communications. There seems to be two divergent technical approaches on how to provide these capabilities: one associated with the use of a fixed length Protocol Data Unit (PDU) i.e., a fixed length transfer frame, and the other advocating the use of a variable length transfer frame. The objective of this paper is to evaluate the pros and cons of these two approaches within the context of existing Consultative Committee for Space Data Systems (CCSDS) Space Data Link Protocols and Channel Coding Recommendations for all space links: space to ground (return) link, ground to space (forward) link and space to space (proximity) links.

Kazz, Greg J↗

Extending the Licklider Transmission Protocol to Multi-Band Links

Most deep space missions return data to Earth using links operating at a single frequency band. Indeed, their data requirements are low enough that bandwidth regulations do not constrain the system. In contrast, spacecraft such as Kepler or Europa Clipper are transitioning to a new operational paradigm where engineering and science data are transmitted through simultaneous links operating at different frequency bands (henceforth termed multi-band links). This ensures, for instance, that critical data is correctly received using a well characterized X-band link, while science data at a much larger data rate can be returned efficiently (both in terms of bandwidth and energy) through a Ka-band link.Having a spacecraft establish two simultaneous links with a ground station opens a large span of potential improvements for space communications and mission operations. In this paper, we consider the problem of running a Licklider Transmission Protocol (LTP) session over a multi-band link. LTP is an implementation of a selective Automatic Repeat reQuest (ARQ) protocol, i.e. it ensures correct delivery of data over an error prone link with potentially long propagation delays. To maximize its efficiency in deep space environments, LTP operates in deferred-ACK mode and is typically included as one of the core protocols in the Delay Tolerant Networking (DTN) suite.The contributions of this paper are as follows: First, we propose an extension to LTP for multi-band links (denoted MBLTP) and sketch how it can be implemented without modifying the current definition of LTP data units. Next, we develop bounds on the performance of MBLTP when transmitting a single data file over a multi-band link. Three metrics are considered, file expected delivery time, total energy spent and bundle jitter. The results of the analytic model are first benchmarked against simulations to ensure validity, and then compared against the performance of both traditional LTP and Parallel LTP (PLTP).We demonstrate that MBLTP can significantly reduce the latency and jitter with which data products are delivered to destination over a deep space link compared to LTP at moderate energy cost. Similarly, we also demonstrate that MBLTP outperforms PLTP in all considered metrics.

Sanchez Net, Marc↗

Validation of Multisystem Countermeasures Protocol for Spaceflight during Antarctica Winter-over at Palmer Station (Palmer Countermeasures)

Exploration-class missions beyond the Van Allen belt to the Moon and then Mars will begin soon. Low-Earth orbital spaceflight results in the persistent perturbation of the human immune system, characterized by reductions in T and NK cell function, altered cytokine profiles, and the reactivation of latent herpesviruses. While these alterations have not caused widespread clinical issues, some crewmembers experience immune-related adverse events, including manifestations of symptomatic herpes viral reactivation, allergy, and respiratory distress. Because future deep-space exploration missions will be of unprecedented duration, it is reasonable to hypothesize that the immune perturbations observed aboard International Space Station (ISS) will intensify during longer missions in deep space, thereby placing crewmembers at elevated clinical risk. Thus, it is imperative to preserve the immune vigilance of astronauts by developing a countermeasure strategy. Of all the Earth analogs studied to date, an Antarctica winter-over (AWO) mission most closely reproduces the spaceflight experience: prolonged deployment, extreme environment, circadian misalignment, isolation, station lifestyle, and personal risk. The US maintains three primary stations in Antarctica: South Pole Station, McMurdo, and Palmer. Previous studies suggest that stations located near the interior of Antarctica (South Pole, McMurdo) have confounding effects on the immune system due to persistent hypobaric hypoxia. Thus, it was hypothesized that winter-over at a coastal station (Palmer) would be more akin to spaceflight due to its normoxic but still extreme environment. Therefore, AWO at Palmer Station was chosen as the platform for testing and validating the effectiveness of a NASA multi-system countermeasures protocol designed for deep space missions. The array of countermeasure protocols and monitoring methods deployed for each AWO will consist of diet modifications, nutritional supplementation, prescribed aerobic and resistive exercise, and a protocol of stress relieving virtual reality exercises. A multitude of biological sample types, including blood, saliva, and hair will be collected in tandem with the countermeasures in order to examine the combined effectiveness of the countermeasures. Samples and logs from subjects will be transported from Palmer Station to Johnson Space Center for further processing and distribution to co-investigators at the end of each winter-over. Extracted samples will be analyzed by appropriate testing platforms (Multiplex, qPCR, ELISA, etc.) to monitor alterations in leukocyte distribution, T cell and NK function, cytokine profiles, reactivation of latent herpesviruses, and nutritional factors. The data collected will be compared to a control year in which no countermeasures were deployed to evaluate the overall effectiveness of the analog and to validate the candidate immune countermeasure strategy. With the completion of the Antarctica Winter-Over (WO) 2022 control year, samples for 13 subjects have been successfully returned from Antarctica to NASA/JSC for further processing and distribution to Co-Investigators. WO 2023, the first countermeasure year, has also commenced with 11 subject consenting and performing their base line data collections (BDC) held in Chile. Another 5 subjects, who were already stationed at Palmer Station, Antarctica, joined as participates in the investigation. These 5 subjects were consented, but no BDC was able to be collected due to their joining in-mission. Therefore, there will be a total of 16 subjects participating in Antarctica's 2023 Winter-Over.

Cody L Gutierrez↗

Validation of Multisystem Countermeasures Protocol for Spaceflight during Antarctica Winter-over at Palmer Station (Palmer Countermeasures)

Stressors associated with spaceflight induce persistent immune compromise in astronauts which increase subclinical latent virus reactivation. In select crews, adverse clinical events have been documented. Antarctica winter-over (AWO) mission most closely reproduces these mission stressors: prolonged deployment, extreme environment, circadian misalignment, isolation, station lifestyle, and personal risk. The US maintains three primary stations in Antarctica: South Pole Station, McMurdo, and Palmer. Previous studies suggest that stations located near the interior of Antarctica (South Pole, McMurdo) have confounding effects on the immune system due to persistent hypobaric hypoxia. We hypothesized that winter-over at a coastal station (Palmer) would be more akin to spaceflight due to its normoxic but still extreme environment. Therefore, AWO at Palmer Station was selected, and validated in a pilot study [2], as the platform for testing and validating the effectiveness of an immune-restorative countermeasure protocol designed for deep space missions. Specifics include diet modifications, nutritional supplementation (vitamin D, probiotic, etc.), prescribed aerobic and resistive exercise, and a protocol of stress relieving virtual reality exercises. A multitude of biological sample types, including blood, saliva, and hair will be collected in tandem with the countermeasures in order to examine the combined effectiveness of the countermeasures. Samples and logs from subjects will be transported from Palmer Station to Johnson Space Center for further processing and distribution to co-investigators at the end of each winter-over. Extracted samples will be analyzed by appropriate testing platforms (Multiplex, qPCR, ELISA, etc.) to monitor alterations in leukocyte distribution, T cell and NK function, cytokine profiles, reactivation of latent herpesviruses, and nutritional factors. The data collected will be compared to a control year in which no countermeasures were deployed to evaluate the overall effectiveness of the analog and to validate the candidate immune countermeasure strategy. AWO 2023 concluded with the 4th in-mission timepoint conducted in September 2023. Samples for 16 subjects, including blood, saliva, hair, surveys, and PCR data, were all successfully returned from Antarctica to NASA/JSC mid-November 2023. Samples have since been distributed to co-investigators for further processing and analysis. With the completion of the first countermeasure year, preliminary data on the effectiveness of the deep-space protocol is being evaluated, however, no conclusions can be drawn yet until the completion of the second AWO countermeasure year, AWO 2024. AWO 2024 commenced in late-March 2024, with 13 subjects consenting and performing their baseline data collections (BDCs). Unique to the 2024 deployment, NSF lifted certain COVID restrictions and rallied the crewmembers in Punta Arenas, Chile. All NSF activities were transferred to this location and NASA was allowed, for the first time, to perform consent briefings, baseline samplings and training in person. This augment greatly increased the likelihood of success for the overwinter activities.

Cody L Gutierrez↗

Separation Assurance in Urban Air Mobility Systems Using Shared Scheduling Protocols

Ensuring safe separation between aircraft is a critical challenge in air traffic management, particularly in urban air mobility (UAM) environments where high traffic density and low altitudes require precise control. In these environments, conflicts often arise at the intersections of flight corridors, posing significant risks. We propose a tactical separation approach leveraging shared scheduling protocols, originally designed for Ethernet networks and operating systems, to coordinate access to these intersections. Using a decentralized Markov decision process framework, the proposed approach enables aircraft to autonomously adjust their speed and timing as they navigate these critical areas, maintaining safe separation without a central controller. We evaluate the effectiveness of this approach in simulated UAM scenarios, demonstrating its ability to reduce separation violations to zero while acknowledging trade-offs in flight times as traffic density increases. Additionally, we explore the impact of non-compliant aircraft, showing that while shared scheduling protocols can no longer guarantee safe separation, they still provide significant improvements over systems without scheduling protocols.

system safety↗

Validation of Multisystem Countermeasures Protocol for Spaceflight during Antarctica Winter-over at Palmer Station (Palmer Countermeasures)

Stressors associated with spaceflight induce persistent immune compromise in astronauts which increase subclinical latent virus reactivation. In select crews, adverse clinical events have been documented. Antarctica winter-over (AWO) mission most closely reproduces these mission stressors: prolonged deployment, extreme environment, circadian misalignment, isolation, station lifestyle, and personal risk. The US maintains three primary stations in Antarctica: South Pole Station, McMurdo, and Palmer. Previous studies suggest that stations located near the interior of Antarctica (South Pole, McMurdo) have confounding effects on the immune system due to persistent hypobaric hypoxia. We hypothesized that winter-over at a coastal station (Palmer) would be more akin to spaceflight due to its normoxic but still extreme environment. Therefore, AWO at Palmer Station was selected, and validated in a pilot study, as the platform for testing and validating the effectiveness of an immune-restorative countermeasure protocol designed for deep space missions. Specifics include diet modifications, nutritional supplementation (vitamin D, probiotic, etc.), prescribed aerobic and resistive exercise, and a protocol of stress relieving virtual reality exercises. A multitude of biological sample types, including blood, saliva, and hair will be collected in tandem with the countermeasures in order to examine the combined effectiveness of the countermeasures. Samples and logs from subjects will be transported from Palmer Station to Johnson Space Center for further processing and distribution to co-investigators at the end of each winter-over. Extracted samples will be analyzed by appropriate testing platforms (Multiplex, qPCR, ELISA, etc.) to monitor alterations in leukocyte distribution, T cell and NK function, cytokine profiles, reactivation of latent herpesviruses, and nutritional factors. The data collected will be compared to a control year in which no countermeasures were deployed to evaluate the overall effectiveness of the analog and to validate the candidate immune countermeasure strategy. AWO 2023 concluded with the 4th in-mission timepoint conducted in September 2023. Samples for 16 subjects, including blood, saliva, hair, surveys, and PCR data, were all successfully returned from Antarctica to NASA/JSC mid-November 2023. Samples have since been distributed to co-investigators for further processing and analysis. With the completion of the first countermeasure year, preliminary data on the effectiveness of the deep-space protocol is being evaluated, however, no conclusions can be drawn yet until the completion of the second AWO countermeasure year, AWO 2024. AWO 2024 commenced in late-March 2024, with 13 subjects consenting and performing their baseline data collections (BDCs). Unique to the 2024 deployment, NSF lifted certain COVID restrictions and rallied the crewmembers in Punta Arenas, Chile. All NSF activities were transferred to this location and NASA was allowed, for the first time, to perform consent briefings, baseline samplings and training in person. This augment greatly increased the likelihood of success for the overwinter activities.

Cody L Gutierrez↗

Delay Tolerant Networking - Bundle Protocol Simulation

In this paper, we report on the addition of MACHETE models needed to support DTN, namely: the Bundle Protocol (BP) model. To illustrate the useof MACHETE with the additional DTN model, we provide an example simulation to benchmark its performance. We demonstrate the use of the DTN protocol and discuss statistics gathered concerning the total time needed to simulate numerous bundle transmissions.

licklider protocol↗

Point-to-Point Multicast Communications Protocol

This paper describes a protocol to support point-to-point interprocessor communications with multicast. Dynamic, cut-through routing with local flow control is used to provide a high-throughput, low-latency communications path between processors. In addition multicast transmissions are available, in which copies of a packet are sent to multiple destinations using common resources as much as possible. Special packet terminators and selective buffering are introduced to avoid a deadlock during multicasts. A simulated implementation of the protocol is also described.

PROTOCOLS↗

Outcome analysis of individualized vestibular rehabilitation protocols

OBJECTIVE: To determine the outcome of vestibular rehabilitation protocols in subjects with peripheral vestibular disorders compared with normal and abnormal control subjects. STUDY DESIGN: Prospective study using repeated measure, matched control design. Subjects were solicited consecutively according to these criteria: vestibular disorder subjects who had abnormal results of computerized dynamic posturography (CDP) sensory organization tests (SOTs) 5 and 6 and underwent rehabilitation; vestibular disorder subjects who had abnormal results of SOTs 5 and 6 and did not undergo rehabilitation; and normal subjects (normal SOTs). SETTING: Tertiary neurotology clinic. SUBJECTS: Men and women over age 18 with chronic vestibular disorders and chief complaints of unsteadiness, imbalance, and/or motion intolerance, and normal subjects. INTERVENTIONS: Pre- and post-rehabilitation assessment included CDP, vestibular disability, and activities of daily living questionnaires. Individualized rehabilitation plans were designed and implemented to address the subject's specific complaints and functional deficits. Supervised sessions were held at weekly intervals, and self-administered programs were devised for daily home use. MAIN OUTCOME MEASURES: CDP composite and SOT scores, number of falls on CDP, and self-assessment questionnaire results. RESULTS: Subjects who underwent rehabilitation (Group A) showed statistically significant improvements in SOTs, overall composite score, and reduction in falls compared with abnormal (Group B) control groups. Group A's performances after rehabilitation were not significantly different from those of normal subjects (Group C) in SOTs 3 through 6, and close to normal on SOTs 1 and 2. Subjects in Group A also reported statistically significant symptomatic improvement. CONCLUSIONS: Outcome measures of vestibular protocol physical therapy confirmed objective and subjective improvement in subjects with chronic peripheral vestibular disorders. These findings support results reported by other investigators.

NASA Discipline Neuroscience↗

Replacing the CCSDS Telecommand Protocol with Next Generation Uplink

Better performing Forward Error Correction on the forward link along with adequate power in the data open an uplink operations trade space that enable missions to: Command to greater distances in deep space (increased uplink margin) Increase the size of the payload data (latency may be a factor) Provides space for the security header/trailer of the CCSDS Space Data Link Security Protocol Note: These higher rates could be used for relief of emergency communication margins/rates and not limited to improving top-end rate performance. A higher performance uplink could also reduce the requirements on flight emergency antenna size and/or the performance required from ground stations. Use of a selective repeat ARQ protocol may increase the uplink design requirements but the resultant development is deemed acceptable, due the factor of 4 to 8 potential increase in uplink data rate.

Low Density Parity Check (LDPC)↗

Protocol Dependent Frictional Granular Jamming Simulations: Cyclical, Compression and Expansion

Granular matter takes many paths to pack in natural and industrial processes. The path influences the packing microstructure, particularly for frictional grains. We perform discrete element modeling simulations of different paths to construct packings of frictional spheres. Specifically, we explore four stress-controlled protocols implementing packing expansions and compressions in various combinations thereof. We characterize the eventual packed states through their dependence of the packing fraction and coordination number on packing pressure, identifying non-monotonicities with pressure that correlate with the fraction of frictional contacts. These stress-controlled, bulk-like particle simulations access very low-pressure packings, namely, the marginally stable limit, and demonstrate the strong protocol dependence of frictional granular matter.

DEM↗

A quarantine protocol for analysis of returned extraterrestrial samples

A protocol is presented for the analysis at an earth-orbiting quarantine facility of return samples of extraterrestrial material that might contain (nonterrestrial) life forms. The protocol consists of a series of tests designed to determine whether the sample, conceptualized as a 1-kg sample of Martian soil, is free from nonterrestrial biologically active agents and so may safely be sent to a terrestrial containment facility, or it exhibits biological activity requiring further (second-order) testing outside the biosphere. The first-order testing procedure seeks to detect the presence of any replicating organisms or toxic substances through a series of experiments including gas sampling, analysis of radioactivity, stereomicroscopic inspection, chemical analysis, microscopic examination, the search for metabolic products under growth conditions, microbiologicl assays, and the challenge of cultured cells with any agents found or with the extraterrestrial material as is. Detailed plans for the second-order testing would be developed in response to the actual data received from primary testing.

Bagby, J. R.↗

Communications protocols for a fault tolerant, integrated local area network for Space Station applications

The evolutionary growth of the Space Station and the diverse activities onboard are expected to require a hierarchy of integrated,local area networks capable of supporting data, voice and video communications. In addition, fault tolerant network operation is necessary to protect communications between critical systems attached to the net and to relieve the valuable human resources onboard Space Station of day-to-day data system repair tasks. An experimental, local area network is being developed which will serve as a testbed for investigating candidate algorithms and technologies for a fault tolerant, integrated network. The establishment of a set of rules or protocols which govern communications on the net is essential to obtain orderly and reliable operation. A hierarchy of protocols for the experimental network is presented and procedures for data and control communications are described.

Meredith, B. D.↗

Performance analysis of the ALOHA protocol with replication in a fading channel for the Mobile Satellite Experiment

The analysis of the ALOHA random access protocol for communications channels with fading is presented. The protocol is modified to send multiple contiguous copies of a message at each transmission attempt. Both pure and slotted ALOHA channels are considered. A general two state model is used for the channel error process to account for the channel fading memory. It is shown that greater throughput and smaller delay may be achieved using repetitions. The model is applied to the analysis of the delay-throughput performance in a fading mobile communications environment. Numerical results are given for NASA's Mobile Satellite Experiment.

Clare, L. P.↗