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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 181 records · Page 10
All sourcesNASA NTRSDOE OSTI
DOE OSTI2024

Characteristics of a cost-effective blood test for colorectal cancer screening

Background: Blood-based biomarker tests can potentially change the landscape of colorectal cancer (CRC) screening. We characterize the conditions under which blood test screening would be as effective and cost-effective as annual fecal immunochemical testing or decennial colonoscopy. Methods: We used the 3 Cancer Information and Surveillance Modeling Network–Colon models to compare scenarios of no screening, annual fecal immunochemical testing, decennial colonoscopy, and a blood test meeting Centers for Medicare & Medicaid (CMS) coverage criteria (74% CRC sensitivity and 90% specificity). We varied the sensitivity to detect CRC (74%-92%), advanced adenomas (10%-50%), screening interval (1-3 years), and test cost ($25-$500). Primary outcomes included quality-adjusted life-years (QALY) gained from screening and costs for a US average-risk cohort of individuals aged 45 years. Results: Annual fecal immunochemical testing yielded 125-163 QALY gained per 1000 at a cost of 3811-5384 dollars per person, whereas colonoscopy yielded 132-177 QALY gained at a cost of 5375-7031 dollars per person. A blood test with 92% CRC sensitivity and 50% advanced adenoma sensitivity yielded 117-162 QALY gained if used every 3 years and 133-173 QALY gained if used every year but would not be cost-effective if priced above $$125 per test. If used every 3 years, a $500 blood test only meeting CMS coverage criteria yielded 83-116 QALY gained at a cost of $8559-$9413 per person. Conclusion: Blood tests that only meet CMS coverage requirements should not be recommended to patients who would otherwise undergo screening by colonoscopy or fecal immunochemical testing because of lower benefit. Blood tests need higher advanced adenoma sensitivity (above 40%) and lower costs (below $125) to be cost-effective.

60 APPLIED LIFE SCIENCES↗
NASA NTRS1975

Results of test 0A82 in the NASA/LRC 31 inch CFHT on an 0.010-scale model (32-0) of the space shuttle configuration 3 to determine RCS jet flow field interaction and to investigate RT real gas effects

Tests were conducted in the NASA Langley Research Center 31-inch Continuous Flow Hypersonic Wind Tunnel to determine RCS jet interaction effects on hypersonic aerodynamic characteristics and to investigate RT (gas constant times temperature) scaling effects on the RCS similitude. The model was an 0.010-scale replica of the Space Shuttle Orbiter Configuration 3. Hypersonic aerodynamic data were obtained from tests at Mach 10.3 and dynamic pressures of 200, 150, 125, and 100 psf. The RCS modes of pitch, yaw, and roll at free flight dynamic pressure simulation of 20 psf were investigated.

Thornton, D. E.↗
NASA NTRS2018

Guideline for Single-Event Effect (SEE) Testing of System on a Chip (SOC) Devices

The use of complex single and multicore processors with significant cache memory, on-chip peripherals, memory controllers, and high speed input/output (IO) that integrate many of the parts of a traditional computer system is becoming more common in space applications. Such devices are often referred to as system on a chip devices (SOCs), even though the term is used somewhat inaccurately due to the lack of analog and mixed signal subcircuits. These devices are complex combinations of single- or multi-core processors with memory controllers, high-speed input/output (IO), and other peripheral structures that formerly would have been handled by off-chip resources. In the past the processors were tested for single event effects (SEE) separately, and the peripherals were often put into custom application-specific integrated circuits (ASICs) along with other resources required by the user. Performance and cost pressures have pushed commercial devices to incorporate many of the functional blocks into a single chip, an SOC. The NASA Electronic Parts and Packaging Program (NEPP) has been examining ways to perform SEE radiation hardness assurance (RHA) testing of these processor-centric SOCs to achieve reasonable understanding of their performance in space missions.

Guertin, Steven M.↗
NASA NTRS2016

Facility Effect Characterization Test of NASA's HERMeS Hall Thruster

A test to characterize the effect of varying background pressure on NASA's 12.5-kW Hall Effect Rocket with Magnetic Shielding had being completed. This thruster is the baseline propulsion system for the Solar Electric Propulsion Technology Demonstration Mission (SEP TDM). Potential differences in thruster performance and oscillation characteristics when in ground facilities versus on-orbit are considered a primary risk for the propulsion system of the Asteroid Redirect Robotic Mission, which is a candidate for SEP TDM. The first primary objective of this test was to demonstrate that the tools being developed to predict the zero-background-pressure behavior of the thruster can provide self-consistent results. The second primary objective of this test was to provide data for refining a physics-based model of the thruster plume that will be used in spacecraft interaction studies. Diagnostics deployed included a thrust stand, Faraday probe, Langmuir probe, retarding potential analyzer, Wien filter spectrometer, and high-speed camera. From the data, a physics-based plume model was refined. Comparisons of empirical data to modeling results are shown.

Electric Propulsion↗
NASA NTRS1995

Dynamic ground effects flight test of the NASA F-15 aircraft

Aerodynamic characteristics of an aircraft may significantly differ when flying close to the ground rather than when flying up and away. Recent research has also determined that dynamic effects (i.e., sink rate) influence ground effects (GE). A ground effects flight test program of the F-15 aircraft was conducted to support the propulsion controlled aircraft (PCA) program at the NASA Dryden Flight Research Center. Flight data was collected for 24 landings on seven test flights. Dynamic ground effects data were obtained for low- and high-sink rates, between 0.8 and 6.5 ft/sec, at two approach speed and flap combinations. These combinations consisted of 150 kt with the flaps down (30 deg deflection) and 170 kt with the flaps up (0 deg deflection), both with the inlet ramps in the full-up position. The aerodynamic coefficients caused by ground effects were estimated from the flight data. These ground effects data were correlated with the aircraft speed, flap setting, and sink rate. Results are compared to previous flight test and wind-tunnel ground effects data for various wings and for complete aircraft.

Corda, Stephen↗
NASA NTRS1988

Space Shuttle solid rocket motor testing for return to flight - Transient Pressure Test Article test program

The Transient Pressure Test Article (TPTA) test program, which is being conducted at a new facility at NASA-Marshall, is described. The facility is designed to test and verify the sealing capability of the redesigned solid rocket motor's (RSRM) field, igniter, and nozzle joints. The test article consists of full-scale RSRM hardware loaded with inert propellant and assembled in a short stack configuration. The test facility is described as well as test implementation, test effectiveness, and test results.

Vibbart, Charles M.↗
NASA NTRS2021

The Future of Electronics Single Event Effects (SEE) Testing

In this presentation, the driving factors changing the world of single-event effects (SEE) testing will be discussed. This includes both semiconductor technological advances and morphing space system philosophies. Considerations for meeting these new challenges will then follow.

Kenneth A Label↗
NASA NTRSDate not supplied

Upwind Buildings Effects on Test Section Performance of the NFAC 80- by 120-Foot Wind Tunnel

In 2013, a new development began that would put multi-story buildings within the exclusion zone of the 80- by 120- Foot Wind Tunnel (80x120) inlet that exceeded the then existing building height restriction. This raised questions concerning whether the tunnel could operate within the acceptable turbulence limits of ≤ 0.5% in the axial direction over 75% area in the wind tunnel test section. The goal of this testing was to determine the validity of this hypothesis. Testing was performed using the 1/50th-scale model of the 80- by 120-FootWind Tunnel within the full-scale facility test section to characterize the model’s test section turbulence levels as a function of wind direction with the presence of the upwind buildings that are currently being constructed. This paper reports the first testing performed to date on the 80x120 inlet as-built under controlled test conditions for wind magnitude and wind onset direction for a variety of buildings in the inlet external flow field, including no buildings (the control case). This testing determined that, at rated operational conditions the upwind blockages caused no increase in turbulence intensity levels measured in the test section and, in some limited cases, caused the turbulence levels to decrease. Lastly, looking at generic rectangular blockages showed that, to have a discernible effect on test section turbulence levels, scaled 100-ft tall blockages need to be within 600 ft of the existing inlet.

Upwind Buildings Effects↗
NASA NTRS1988

Modeling and data analysis of the NASA-WSTF frictional heating apparatus - Effects of test parameters on friction coefficient

A theoretical model is being developed jointly by the NASA White Sands Test Facility (WSTF) and the University of California at Santa Barbara (UCSB) to analyze data generated from the WSTF frictional heating test facility. Analyses of the data generated in the first seconds of the frictional heating test are shown to be effective in determining the friction coefficient between the rubbing interfaces. Different friction coefficients for carobn steel and Monel K-500 are observed. The initial condition of the surface is shown to affect only the initial value of the friction coefficient but to have no significant influence on the average steady-state friction coefficient. Rotational speed and the formation of oxide film on the rotating surfaces are shown to have a significant effect on the friction coefficient.

Zhu, Sheng-Hu↗
NASA NTRS2006

Lightweight Ablative and Ceramic Thermal Protection System Materials for NASA Exploration Systems Vehicles

As a collaborative effort among NASA Centers, the "Lightweight Nonmetallic Thermal Protection Materials Technology" Project was set up to assist mission/vehicle design trade studies, to support risk reduction in thermal protection system (TPS) material selections, to facilitate vehicle mass optimization, and to aid development of human-rated TPS qualification and certification plans. Missions performing aerocapture, aerobraking, or direct aeroentry rely on advanced heatshields that allow reductions in spacecraft mass by minimizing propellant requirements. Information will be presented on candidate materials for such reentry approaches and on screening tests conducted (material property and space environmental effects tests) to evaluate viable candidates. Seventeen materials, in three classes (ablatives, tiles, and ceramic matrix composites), were studied. In additional to physical, mechanical, and thermal property tests, high heat flux laser tests and simulated-reentry oxidation tests were performed. Space environmental effects testing, which included exposures to electrons, atomic oxygen, and hypervelocity impacts, was also conducted.

Valentine, Peter G.↗
NASA NTRS1990

Experiment K-6-16. Morphological examination of rat testes. The effect of Cosmos 1887 flight on spermatogonial population and testosterone level in rat testes

Testes from rats flown on Cosmos 1887 for twelve and a half days were compared to basal control, synchronous control and vivarium maintained rats. When the mean weights of flight testes, normalized for weight/100 gms, were compared to the vivarium controls they were 6.7 percent lighter. Although the flight testes were lighter than the synchronous, the difference is not significant. Counts of spermatogonial cells from 5 animals in each group revealed a 4 percent decrease in flight compared to vivarium controls. In both cases the t-Test significance was less than 0.02. The serum testosterone levels of all animals (flight, synchronous and vivarium) were significantly below the basal controls.

Philpott, D. E.↗
NASA NTRS2012

Space Environmental Effects (SEE) Testing Capability: NASA/Marshall Space Flight Center

Understanding the effects of the space environment on materials and systems is fundamental and essential for mission success. If not properly understood and designed for, the space environment can lead to materials degradation, reduction of functional lifetime, and system failure. Ground based testing is critical in predicting performance NASA/MSFC's expertise and capabilities make up the most complete SEE testing capability available.

DeWittBurns, H.↗
NASA NTRS2021

The Use of High Energy Heavy Ion Facilities for Single Event Effects (SEE) Testing: A Perspective on Return on Investment (ROI)

With challenges related to testing highly complex integrated circuits as well as entire systems continuing to grow, the use of higher energy heavy ions for single-event effects (SEE) testing becomes a critical technical need. This presentation, however, focuses only partially on the technical side with the main emphasis on the economics of using a high-energy heavy ion beam and comparing via notional cost models for testing.

Kenneth A. LaBel↗