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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 199 records · Page 11
All sourcesNASA NTRSDOE OSTI
DOE OSTI2025

Exploring phage–host interactions in Burkholderia cepacia complex bacterium to reveal host factors and phage resistance genes using CRISPRi functional genomics and transcriptomics

Complex interactions of bacteriophages with their bacterial hosts determine phage host range and infectivity. While phage defense systems and host factors have been identified in model bacteria, they remain challenging to predict in non-model bacteria. In this paper, we integrate functional genomics and transcriptomics to investigate phage–host interactions, revealing active phage resistance and host factor genes in Burkholderia cenocepacia K56-2. Burkholderia cepacia complex species are commonly found in soil and are opportunistic pathogens in immunocompromised patients. We studied infection of B. cenocepacia K56-2 with Bcep176, a temperate phage isolated from Burkholderia multivorans. A genome-wide dCas9 knockdown library targeting B. cenocepacia K56-2 was constructed, and a pooled infection experiment identified 63 novel genes or operons coding for candidate host factors or phage resistance genes. The activities of a subset of candidate host factor and resistance genes were validated via single-gene knockdowns. Transcriptomics of B. cenocepacia K56-2 during Bcep176 infection revealed that expression of genes coding for host factor and resistance candidates identified in this screen was significantly altered during infection by 4 h post-infection. Identifying which bacterial genes are involved in phage infection is important to understand the ecological niches of B. cenocepacia and its phages, and for designing phage therapies.

Bacterial Pathogenesis↗
DOE OSTI2024

New Tank Mapping Method Improves Waste Removal Process

Savannah River Mission Completion is the Liquid Waste (LW) contractor at the Savannah River Site (SRS). The LW mission is tasked with treating and disposing of legacy nuclear waste. There are multiple facilities involved in this work, including the Concentration, Storage, and Transfer Facilities (CSTF), the Defense Waste Processing Facility (DWPF), the Salt Waste Processing Facility (SWPF), and the Saltstone Production Facility (SPF). The CSTF includes 43 underground waste tanks used to store and support processing of radioactive liquid waste. Waste removal activities, such as salt dissolution campaigns and sludge agitation, are conducted within the CSTF waste tanks to convert the waste into a form that allows for downstream processing at other LW facilities. While performing these waste removal campaigns, camera inspections are performed to assess the quantity and distribution of the remaining waste within the waste tank (i.e. saltcake or sludge). Understanding the quantity and distribution of the salt/sludge within the waste tanks allows for improved waste removal strategies (e.g. mixing pump operation) and refined safety controls. Typically, several camera inspections are performed during a waste removal transfer to verify the elevation of the visible salt/sludge mounds against the known elevation of the liquid surface. The camera inspection footage must then be interpreted by a trained engineer who will develop a 2-D map that depicts the waste distribution at various elevations within the waste tank. This tank mapping is then used in conjunction with conservative assumptions to evaluate the volume of saltcake or sludge that is present within the waste tank.

Mini, Melany↗
NASA NTRS1992

Situation assessment in the Paladin tactical decision generation system

Paladin is a real-time tactical decision generator for air combat engagements. Paladin uses specialized knowledge-based systems and other Artificial Intelligence (AI) programming techniques to address the modern air combat environment and agile aircraft in a clear and concise manner. Paladin is designed to provide insight into both the tactical benefits and the costs of enhanced agility. The system was developed using the Lisp programming language on a specialized AI workstation. Paladin utilizes a set of air combat rules, an active throttle controller, and a situation assessment module that have been implemented as a set of highly specialized knowledge-based systems. The situation assessment module was developed to determine the tactical mode of operation (aggressive, defensive, neutral, evasive, or disengagement) used by Paladin at each decision point in the air combat engagement. Paladin uses the situation assessment module; the situationally dependent modes of operation to more accurately represent the complex decision-making process of human pilots. This allows Paladin to adapt its tactics to the current situation and improves system performance. Discussed here are the details of Paladin's situation assessment and modes of operation. The results of simulation testing showing the error introduced into the situation assessment module due to estimation errors in positional and geometric data for the opponent aircraft are presented. Implementation issues for real-time performance are discussed and several solutions are presented, including Paladin's use of an inference engine designed for real-time execution.

Mcmanus, John W.↗
NASA NTRS1992

Psychological training of NASA astronauts for extended missions

The success of operational teams working in remote and hostile environments rests in large part on adequate preparation of those teams prior to emplacement in field settings. Psychological training, directed at the maintenance of crew health and performance becomes increasingly important as space missions grow in duration and complexity. Methods: Topics to be discussed include: the conceptual framework of psychological training; needs analysis; content and delivery options; methods of assessing training efficacy; use of testbeds and analogies and the relationship of training to crew selection and real-time support activities. Results and Conclusions: This paper will discuss the psychological training approach being developed at the NASA/JSC Behavior and Performance Laboratory. This approach will be compared and contrasted with those underway in the U.S. Department of Defense and in other space agencies.

Holland, A. W.↗
NASA NTRS2005

Next Generation Launch Technology Program Lessons Learned

In November 2002, NASA revised its Integrated Space Transportation Plan (ISTP) to evolve the Space Launch Initiative (SLI) to serve as a theme for two emerging programs. The first of these, the Orbital Space Plane (OSP), was intended to provide crew-escape and crew-transfer functions for the ISS. The second, the NGLT Program, developed technologies needed for safe, routine space access for scientific exploration, commerce, and national defense. The NGLT Program was comprised of 12 projects, ranging from fundamental high-temperature materials research to full-scale engine system developments (turbine and rocket) to scramjet flight test. The Program included technology advancement activities with a broad range of objectives, ultimate applications/timeframes, and technology maturity levels. An over-arching Systems Engineering and Analysis (SE&A) approach was employed to focus technology advancements according to a common set of requirements. Investments were categorized into three segments of technology maturation: propulsion technologies, launch systems technologies, and SE&A.

Cook, Stephen↗
NASA NTRS1994

Intelligent vehicle control: Opportunities for terrestrial-space system integration

For 11 years the Department of Defense has cooperated with a diverse array of other Federal agencies including the National Institute of Standards and Technology, the Jet Propulsion Laboratory, and the Department of Energy, to develop robotics technology for unmanned ground systems. These activities have addressed control system architectures supporting sharing of tasks between the system operator and various automated subsystems, man-machine interfaces to intelligent vehicles systems, video compression supporting vehicle driving in low data rate digital communication environments, multiple simultaneous vehicle control by a single operator, path planning and retrace, and automated obstacle detection and avoidance subsystem. Performance metrics and test facilities for robotic vehicles were developed permitting objective performance assessment of a variety of operator-automated vehicle control regimes. Progress in these areas will be described in the context of robotic vehicle testbeds specifically developed for automated vehicle research. These initiatives, particularly as regards the data compression, task sharing, and automated mobility topics, also have relevance in the space environment. The intersection of technology development interests between these two communities will be discussed in this paper.

Shoemaker, Charles↗
NASA NTRS2011

GSFC Supplier Surveillance

Topics covered include: Develop Program/Project Quality Assurance Surveillance Plans The work activities performed by the developer and/or his suppliers are subject to evaluation and audit by government-designated representatives. CSO supports project by selecting on-site supplier representative s by one of several methods: (1) a Defense Contract Management Agency (DCMA) person via a Letter Of Delegation (LOD), (2) an independent assurance contractor (IAC) via a contract Audits, Assessments, and Assurance (A3) Contract Code 300 Mission Assurance Support Contract (MASC)

Kelly, Michael P.↗
NASA NTRS2018

Lightning Imaging Sensor on the International Space Station: Assessments and Results from First Year Operations

Over two decades, the NASA Marshall Space Flight Center, the University of Alabama in Huntsville, and their partners have demonstrated the effectiveness and value of space-based lightning observations as a remote sensing tool for Earth science research and applications, and, in the process, established a robust global lightning climatology. The Lightning Imaging Sensor (LIS) on the Tropical Rainfall Measuring Mission (TRMM) provided global observations of tropical lightning for an impressive 17 years before that mission came to a close in April 2015. Now a space-qualified LIS, built as the flight spare for TRMM, has been installed on the International Space Station (ISS) for a minimum two year mission following its SpaceX launch on February 19, 2017. The LIS, flown as a hosted payload on the Department of Defense Space Test Program-Houston 5 (STP-H5) mission, was delivered to the ISS in the Dragon trunk and robotically installed in an Earth-viewing position on the outside of the ISS. Following successful activation and checkout, LIS has continuously observed the amount, rate, and radiant energy lightning within its field-of-view as it orbits the Earth. Placing LIS on the Space Station provides a great opportunity to not only extend the 17-year TRMM LIS record of tropical lightning measurements but also to expand that coverage to higher latitudes missed by the previous mission. Furthermore, this mission continues the important science focus to better understand the processes which cause lightning, as well as the connections between lightning and subsequent severe weather events. This understanding is a key to improving weather predictions and saving lives and property here in the United States and around the world. The LIS measurements, along with observations from the new Geostationary Lightning Mapper (GLM) operating on NOAA's newest weather satellites, the Geosynchronous Operational Environmental Satellite-16/17 (GOES-16/17), are being used to cross-validate both systems. An especially unique contribution from the ISS platform is the production of real-time lightning data, especially valuable for operational forecasting and warning applications over data sparse regions such as the oceans. Finally, LIS provides simultaneous and complementary observations with other ISS payloads such as the European Space Agency's Atmosphere-Space Interaction Monitor (ASIM) that is exploring the connection between thunderstorms and lightning with terrestrial gamma-ray flashes (TGFs). Leveraging TRMM's well-established processing and data handling assures that LIS data can be quickly delivered to users.

space-based lightning↗
DOE OSTI2024

Advanced Algorithms for Scrutiny of Mandatory State Reports Declarations to the IAEA (Final Project Report)

In compliance with their Comprehensive Safeguards Agreements, based on INFCIRC/153 (corrected) (International Atomic Energy Agency, 1972), States Party to the Treaty on the NonProliferation of Nuclear Weapons (NPT) are obligated to declare to the International Atomic Energy Agency (IAEA) all changes in their nuclear material inventory as well as movement of the material across boundaries of IAEA recognized material balance areas (MBA), inventories and nuclear material balances. This project addresses capabilities to detect irregularities in State reports, thus ensuring their accuracy and completeness, and in the broader context, States’ compliance with safeguards obligations of the NPT. A recent study (Henzl et al., 2022) (lead by this project’s PI) demonstrated how analysis of dynamic correlations in nuclear material movement within the entire fuel cycle of a State (viewed as a single system) can reveal variances consistent with and indicative of “irregular” activities. Expanding on this concept, novel ways to analyze State declarations themselves—again, for the State as a whole entity—will help the IAEA draw accurate safeguards conclusions and trust the validity and authenticity of Stategenerated declaration reports. Introducing new declaration analyses capabilities explored in this project will help to provide credible assurance of both the non-diversion of nuclear material from declared activities and of the absence of undeclared nuclear material and activities in the State in general.

45 MILITARY TECHNOLOGY, WEAPONRY, AND NATIONAL DEF↗
NASA NTRS1995

An atlas of monthly mean distributions of SSMI surface wind speed, AVHRR/2 sea surface temperature, AMI surface wind velocity, TOPEX/POSEIDON sea surface height, and ECMWF surface wind velocity during 1993

The following monthly mean global distributions for 1993 are presented with a common color scale and geographical map: 10-m height wind speed estimated from the Special Sensor Microwave Imager (SSMI) on a United States (U.S.) Air Force Defense Meteorological Satellite Program (DMSP) spacecraft; sea surface temperature estimated from the Advanced Very High Resolution Radiometer (AVHRR/2) on a U.S. National Oceanic and Atmospheric Administration (NOAA) satellite; 10-m height wind speed and direction estimated from the Active Microwave Instrument (AMI) on the European Space Agency (ESA) European Remote Sensing (ERS-1) satellite; sea surface height estimated from the joint U.S.-France Topography Experiment (TOPEX)/POSEIDON spacecraft; and 10-m height wind speed and direction produced by the European Center for Medium-Range Weather Forecasting (ECMWF). Charts of annual mean, monthly mean, and sampling distributions are displayed.

Halpern, D.↗
NASA NTRS2024

Integration of Automated Systems Test Campaign NC-IAS

NASA’s 2022 strategic plan included the goal to catalyze economic growth and drive innovation in the aviation industry, and to address challenges in air transportation and airspace management within the National Airspace System (NAS). The Aeronautics Research Mission Directorate (ARMD) specifically was tasked with leading aviation innovation to enable safe and sustainable air transportation through revolutionary vehicle advances and efficient flight operations. As a part of meeting these objectives and advancing air mobility concepts, NASA initiated the National Campaign (NC) in the Advanced Air Mobility (AAM) Project within the Airspace Operations and Safety Program (AOSP). The NC was designed to support operational demonstrations with industry as well as the research and development needed to support NASA-led research flight demonstrations. Within NC, the Integration of Automated Systems (IAS), an NC activity, tested and evaluated flight deck automation and airspace operations management functions needed to enable Urban Air Mobility (UAM) operations. This was accomplished through a partnership with Sikorsky Aircraft (specifically Sikorsky Innovations), a Lockheed Martin company, and DARPA (Defense Advanced Research Projects Agency), by leveraging two automation-enabled helicopters equipped with unique capabilities that enabled NASA to develop and test two-ship conflict encounters to demonstrate flight path management and hazard avoidance technologies. The enabler in this testing was NASA-developed “Middleware” (MW) software (also known as Expandable Variable Autonomy Architecture, or EVAA), which among other things allowed multiple algorithms to be incorporated into one software build that was hosted on the dissimilar-type Sikorsky helicopters. The IAS test campaign period of performance was from March 2022 through October 2023 and was structured as a phased, or spiral, approach that ultimately led to the first-ever demonstration of two-ship UAM/AAM operations designed to safely choreograph specific conflict encounters and mission scenarios to test the research algorithms for strategic and tactical aircraft deconfliction. Lessons learned are included in the body of the report. Data collected will be used to inform FAA and industry standards groups on the increasingly automated systems needed for future AAM operations. The test encounters developed for these flight tests were proven to be highly predictable, repeatable, and safely exercised flight path planning and Detect and Avoid (DAA) algorithms. These same test encounters should be leveraged by future flight test campaigns to verify that operational safety is not compromised as the AAM architecture matures. Next steps include repeating similar encounters using unmanned aircraft carrying DAA sensors in the National Airspace.

AAM↗
DOE OSTI2024

Complete genomes of Asgard archaea reveal diverse integrated and mobile genetic elements

Asgard archaea are of great interest as the progenitors of Eukaryotes, but little is known about the mobile genetic elements (MGEs) that may shape their ongoing evolution. Here, we describe MGEs that replicate in Atabeyarchaeia, a wetland Asgard archaea lineage represented by two complete genomes. We used soil depth–resolved population metagenomic data sets to track 18 MGEs for which genome structures were defined and precise chromosome integration sites could be identified for confident host linkage. Additionally, we identified a complete 20.67 kbp circular plasmid and two family-level groups of viruses linked to Atabeyarchaeia, via CRISPR spacer targeting. Closely related 40 kbp viruses possess a hypervariable genomic region encoding combinations of specific genes for small cysteine-rich proteins structurally similar to restriction-homing endonucleases. One 10.9 kbp integrative conjugative element (ICE) integrates genomically into theAtabeyarchaeum deiterrae-1chromosome and has a 2.5 kbp circularizable element integrated within it. The 10.9 kbp ICE encodes an expressed Type IIG restriction-modification system with a sequence specificity matching an active methylation motif identified by Pacific Biosciences (PacBio) high-accuracy long-read (HiFi) metagenomic sequencing. Restriction-modification of Atabeyarchaeia differs from that of another coexisting Asgard archaea, Freyarchaeia, which has few identified MGEs but possesses diverse defense mechanisms, including DISARM and Hachiman, not found in Atabeyarchaeia. Overall, defense systems and methylation mechanisms of Asgard archaea likely modulate their interactions with MGEs, and integration/excision and copy number variation of MGEs in turn enable host genetic versatility.

Biochemistry & Molecular Biology↗
NASA NTRS2005

Space Weather Modeling at the Community Coordinated Modeling Center

The Community Coordinated Modeling Center (CCMC) is a multi-agency partnership, which aims at the creation of next generation space weather models. The goal of the CCMC is to support the research and developmental work necessary to substantially increase the present-day modeling capability for space weather purposes, and to provide models for transition to the rapid prototyping centers at the space weather forecast centers. This goal requires dose collaborations with and substantial involvement of the research community. The physical regions to be addressed by CCMC-related activities range from the solar atmosphere to the Earth's upper atmosphere. The CCMC is an integral part of the National Space Weather Program Implementation Plan, of NASA's Living With a Star (LWS) initiative, and of the Department of Defense Space Weather Transition Plan. CCMC includes a facility at NASA Goddard Space Flight Center, as well as distributed computing facilities provided by the US Air Force. CCMC also provides, to the research community, access to state-of-the-art space research models. In this paper we will provide updates on CCMC status, on current plans, research and development accomplishments and goals, and on the model testing and validation process undertaken as part of the CCMC mandate. Special emphasis will be on solar and heliospheric models currently residing at CCMC, and on plans for validation and verification.

Hesse M.↗
NASA NTRS2006

Space Weather Modeling Services at the Community Coordinated Modeling Center

The Community Coordinated Modeling Center (CCMC) is a multi-agency partnership, which aims at the creation of next generation space weather models. The goal of the CCMC is to support the research and developmental work necessary to substantially increase the present-day modeling capability for space weather purposes, and to provide models for transition to the Rapid Prototyping Centers at the space weather forecast centers. This goal requires close collaborations with and substantial involvement of the research community. The physical regions to be addressed by CCMC-related activities range from the solar atmosphere to the Earth's upper atmosphere. The CCMC is an integral part of the National Space Weather Program Implementation Plan, of NASA's Living With a Star (LWS) initiative, and of the Department of Defense Space Weather Transition Plan. CCMC includes a facility at NASA Goddard Space Flight Center. CCMC also provides, to the research community, access to state-of-the-art space research models. In this paper we will provide a description of the current CCMC status, discuss current plans, research and development accomplishments and goals, and describe the model testing and validation process undertaken as part of the CCMC mandate. Special emphasis will be on solar and heliospheric models currently residing at CCMC, and on plans for validation and verification.

Hesse, Michael↗
NASA NTRS2008

The Integrated Medical Model: Statistical Forecasting of Risks to Crew Health and Mission Success

The Integrated Medical Model (IMM) helps capture and use organizational knowledge across the space medicine, training, operations, engineering, and research domains. The IMM uses this domain knowledge in the context of a mission and crew profile to forecast crew health and mission success risks. The IMM is most helpful in comparing the risk of two or more mission profiles, not as a tool for predicting absolute risk. The process of building the IMM adheres to Probability Risk Assessment (PRA) techniques described in NASA Procedural Requirement (NPR) 8705.5, and uses current evidence-based information to establish a defensible position for making decisions that help ensure crew health and mission success. The IMM quantitatively describes the following input parameters: 1) medical conditions and likelihood, 2) mission duration, 3) vehicle environment, 4) crew attributes (e.g. age, sex), 5) crew activities (e.g. EVA's, Lunar excursions), 6) diagnosis and treatment protocols (e.g. medical equipment, consumables pharmaceuticals), and 7) Crew Medical Officer (CMO) training effectiveness. It is worth reiterating that the IMM uses the data sets above as inputs. Many other risk management efforts stop at determining only likelihood. The IMM is unique in that it models not only likelihood, but risk mitigations, as well as subsequent clinical outcomes based on those mitigations. Once the mathematical relationships among the above parameters are established, the IMM uses a Monte Carlo simulation technique (a random sampling of the inputs as described by their statistical distribution) to determine the probable outcomes. Because the IMM is a stochastic model (i.e. the input parameters are represented by various statistical distributions depending on the data type), when the mission is simulated 10-50,000 times with a given set of medical capabilities (risk mitigations), a prediction of the most probable outcomes can be generated. For each mission, the IMM tracks which conditions occurred and decrements the pharmaceuticals and supplies required to diagnose and treat these medical conditions. If supplies are depleted, then the medical condition goes untreated, and crew and mission risk increase. The IMM currently models approximately 30 medical conditions. By the end of FY2008, the IMM will be modeling over 100 medical conditions, approximately 60 of which have been recorded to have occurred during short and long space missions.

Fitts, M. A.↗
NASA NTRS2016

Amazon Forests Response to Droughts: A Perspective from the MAIAC Product

Amazon forests experienced two severe droughts at the beginning of the 21st century: one in 2005 and the other in 2010. How Amazon forests responded to these droughts is critical for the future of the Earth's climate system. It is only possible to assess Amazon forests' response to the droughts in large areal extent through satellite remote sensing. Here, we used the Multi-Angle Implementation of Atmospheric Correction (MAIAC) Moderate Resolution Imaging Spectroradiometer (MODIS) vegetation index (VI) data to assess Amazon forests' response to droughts, and compared the results with those from the standard (Collection 5 and Collection 6) MODIS VI data. Overall, the MAIAC data reveal more realistic Amazon forests inter-annual greenness dynamics than the standard MODIS data. Our results from the MAIAC data suggest that: (1) the droughts decreased the greenness (i.e., photosynthetic activity) of Amazon forests; (2) the Amazon wet season precipitation reduction induced by El Niño events could also lead to reduced photosynthetic activity of Amazon forests; and (3) in the subsequent year after the water stresses, the greenness of Amazon forests recovered from the preceding decreases. However, as previous research shows droughts cause Amazon forests to reduce investment in tissue maintenance and defense, it is not clear whether the photosynthesis of Amazon forests will continue to recover after future water stresses, because of the accumulated damages caused by the droughts.

remote sensing↗
NASA NTRS2022

A Systems Model for System-Wide Safety Safety Demonstrator (SD-1): Wildfire Response Operations

The aim of this internship-based project was to contribute to the ongoing development of a systems model for System-Wide Safety’s first Technical Challenge 5 (TC5) series Safety Demonstrator (SD-1), which will be a demonstration of an In-Time Aviation Safety Management System (IASMS) in emerging wildfire response operations. Using Models-Based Systems Engineering (MBSE) principles to develop the model, I organized and traced previously collected stakeholder needs from the Spring 2022 NASA System-Wide Safety Wildland Firefighting Operations Virtual Workshop (https://nari.arc.nasa.gov/sws-wildfire) to system elements, creating connections which can be used in the future by the project engineers to identify and address requirements gaps throughout the system design process. I also identified and modeled preliminary use case scenarios for aerial assets in the demonstrator and, building on previously produced preliminary high-level models of the 8 SD-1 Services, Functions, and Capabilities (SFCs) and their IASMS data flows, worked to model the Real-Time Risk Assessment (RTRA) tool as an implementation of Risk Assessment and Management that can take in multiple sets of data monitored by SFCs. Project deliverables include stakeholder requirements tables and matrices and systems model diagrams produced with MagicDraw software in the SysML Systems Modeling Language, with eventual plans to connect model diagrams to a Department of Defense Operational Viewpoint (OV-1) graphic, a high-level operational concept graphic that will be used to visualize the SD-1 scenarioin a future phase. The system model serves to provide a common understanding of the scope of and activities necessary for the completion of SD-1,and traces how stakeholder needs are to be addressed.

model-based systems engineering↗
NASA NTRS2004

Facility Activation and Characterization for IPD Oxidizer Turbopump Cold-Flow Testing at NASA Stennis Space Center

The Integrated Powerhead Demonstrator (IPD) is a 250K lbf (1.1 MN) thrust cryogenic hydrogen/oxygen engine technology demonstrator that utilizes a full flow staged combustion engine cycle. The Integrated Powerhead Demonstrator (IPD) is part of NASA's Next Generation Launch Technology (NGLT) program, which seeks to provide safe, dependable, cost-cutting technologies for future space launch systems. The project also is part of the Department of Defense's Integrated High Payoff Rocket Propulsion Technology (IHPRPT) program, which seeks to increase the performance and capability of today s state-of-the-art rocket propulsion systems while decreasing costs associated with military and commercial access to space. The primary industry participants include Boeing-Rocketdyne and GenCorp Aerojet. The intended full flow engine cycle is a key component in achieving all of the aforementioned goals. The IPD Program achieved a major milestone with the successful completion of the IPD Oxidizer Turbopump (OTP) cold-flow test project at the NASA John C. Stennis Space Center (SSC) E-1 test facility in November 2001. A total of 11 IPD OTP cold-flow tests were completed. Following an overview of the NASA SSC E-1 test facility, this paper addresses the facility aspects pertaining to the activation and the cold-flow testing of the IPD OTP. In addition, some of the facility challenges encountered during the test project are addressed.

Sass, J. P.↗