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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 199 records · Page 11

Numerical modeling for an electric-field hyperthermia applicator

Hyperthermia, in conjunction with radiation and chemotherapy for treatment of cancers, is an area of current concern. Experiments have shown that hyperthermia can increase the potency of many chemotherapy drugs and the effectiveness of radiation for treating cancer. A combination of whole body or regional hyperthermia with chemotherapy or radiation should improve treatment results. Conventional methods for inducing whole body hyperthermia, such as exposing a patient in a radiant cabinet or under a hot water blanket, conduct heat very slowly from the skin to the body core. Thus a more efficient system, such as the three-plate electric-field hyperthermia applicator (EHA), is developed. This three-plate EHA has one top plate over and two lower plates beneath the patient. It is driven at 27.12 MHz with 500 Watts through a matching circuit. Using this applicator, a 50 kg pig was successfully heated to 42 C within 45 minutes. However, phantom and animal studies have indicated non-uniform heating near the side of the body. In addition, changes in the size and distance between the electrode plates can affect the heating (or electromagnetic field) pattern. Therefore, numerical models using the method of moments (MOM) or the finite difference time domain (FDTD) technique are developed to optimize the heating pattern of this EHA before it is used for human trials. The accuracy of the numerical modeling has been achieved by the good agreement between the MOM and FDTD results for the three-plate EHA without a biological body. The versatile FDTD technique is then applied to optimize the EHA design with a human body. Both the numerical and measured data in phantom blocks will be presented. The results of this study will be used to design an optimized system for whole body or regional hyperthermia.

Wu, Te-Kao↗

A numerical solution of the supersonic flow over a rearward facing step with transverse non-reacting hydrogen injection

The present investigation represents an application of computational fluid dynamics to a problem associated with the flow in the combustor region of a supersonic combustion ramjet engine (scramjet). The governing equations are considered, taking into account the Navier-Stokes equations, a molecular viscosity calculation, the molecular thermal conductivity, molecular diffusion, and a turbulence model. The employed numerical solution is patterned after the explicit, time-dependent, unsplit, predictor-corrector, finite-difference method given by MacCormack (1969). The calculation is concerned with the supersonic flow over a rearward-facing step with transverse H2 injection at conditions germane to the combustor region of a scramjet engine. The H2 jet acts as an effective body which essentially shields the primary flow from the rearward-facing step, thus substantially changing the wave pattern in the primary flow.

Berman, H. A.↗

A common modality of action of simulated space stresses on the oxidative metabolism of ethylmorphine, aniline and p-nitroanisole by male rat liver.

High gravity, cold and starvation elicited similar responses in male Simonson rats. These responses included a decreased rate in body weight gain, increased metabolism of aniline and p-nitroanisole, and no consistent pattern of change in the metabolism of ethylmorphine. Cold and starvation increased the amount of hepatic cytochrome P-450, while hypobaric-hyperoxia caused no change in any of the parameters measured. When 1% acetone was given to the rats in their drinking water, the effects on drug metabolism were similar to those produced by food restriction in that the metabolism of aniline and p-nitroanisole was increased, and the metabolism of ethylmorphine unchanged. The type I binding spectrum of acetone suggests that it is either a substrate, inhibitor, or both for hepatitic oxidative enzymes.

Furner, R. L.↗

Encounter with Saturn - Voyager 1 imaging science results

As Voyager 1 flew through the Saturn system it returned photographs revealing many new and surprising characteristics of this complicated community of bodies. Saturn's atmosphere has numerous, low-contrast, discrete cloud features and a pattern of circulation significantly different from that of Jupiter. Titan is shrouded in a haze layer that varies in thickness and appearance. Among the icy satellites there is considerable variety in density, albedo, and surface morphology and substantial evidence for endogenic surface modification. Trends in density and crater characteristics are quite unlike those of the Galilean satellites. Small inner satellites, three of which were discovered in Voyager images, interact gravitationally with one another and with the ring particles in ways not observed elsewhere in the solar system. Saturn's broad A, B, and C rings contain hundreds of 'ringlets', and in the densest portion of the B ring there are numerous nonaxisymmetric features. The narrow F ring has three components which, in at least one instance, are kinked and crisscrossed. Two rings are observed beyond the F ring, and material is seen between the C ring and the planet.

Smith, B. A.↗

Complex space multipole theory for scattering and diffraction problems

Classical multipole theory can be extended to multipoles located in complex space and applied in scattering and diffraction problems with the advantage that, if the point of the multipole is correctly chosen, the first term may give an order of magnitude better approximation to the source than when the multipole is in real space. The basic theory, given elsewhere, is presented here in a more straightforward manner and the improvement in radiation pattern is demonstrated for sources of constant polarization. Applications on scattering by spheroidal dielectric bodies and diffraction by a dielectric half-space are discussed.

Lindell, Ismo V.↗

Water Tunnel Flow Visualization Study Through Poststall of 12 Novel Planform Shapes

To determine the flow field characteristics of 12 planform geometries, a flow visualization investigation was conducted in the Langley 16- by 24-Inch Water Tunnel. Concepts studied included flat plate representations of diamond wings, twin bodies, double wings, cutout wing configurations, and serrated forebodies. The off-surface flow patterns were identified by injecting colored dyes from the model surface into the free-stream flow. These dyes generally were injected so that the localized vortical flow patterns were visualized. Photographs were obtained for angles of attack ranging from 10' to 50', and all investigations were conducted at a test section speed of 0.25 ft per sec. Results from the investigation indicate that the formation of strong vortices on highly swept forebodies can improve poststall lift characteristics; however, the asymmetric bursting of these vortices could produce substantial control problems. A wing cutout was found to significantly alter the position of the forebody vortex on the wing by shifting the vortex inboard. Serrated forebodies were found to effectively generate multiple vortices over the configuration. Vortices from 65' swept forebody serrations tended to roll together, while vortices from 40' swept serrations were more effective in generating additional lift caused by their more independent nature.

Gatlin, Gregory M.↗

Results from the Joint US/Russian Sensory-Motor Investigations

In this session, Session FA3, the discussion focuses on the following topics: The Effect of Long Duration Space Flight on the Acquisition of Predictable Targets in Three Dimensional Space; Effects of Microgravity on Spinal Reflex Mechanisms; Three Dimensional Head Movement Control During Locomotion After Long-Duration Space Flight; Human Body Shock Wave Transmission Properties After Long Duration Space Flight; Adaptation of Neuromuscular Activation Patterns During Locomotion After Long Duration Space Flight; Balance Control Deficits Following Long-Duration Space Flight; Influence of Weightlessness on Postural Muscular Activity Coordination; and The Use of Inflight Foot Pressure as a Countermeasure to Neuromuscular Degradation.

Source record↗

The Shock-Wave Patterns on a Cranked-Wing Configuration

The shock-wave patterns of a complex configuration with cranked cruciform wings and a cone-cylinder body were examined to determine the interaction of the body bow wave with the flow field about the wing. Also of interest, was the interaction of the forward (760 sweptback) wing leading-edge wave with the rear (600 sweptback) wing leading-edge wave. The shadowgraph pictures of the model in free flight at a Mach number of 4.9, although not definitive, appear to indicate that the body bow wave crosses the outer wing panel after first being refracted either by the leading-edge wave of the 600 sweptback wing or by pressure fields in the flow crossing the wing.

Sammonds, Robert I.↗

Genetic Regulatory Networks in Embryogenesis and Evolution

The article introduces a series of papers that were originally presented at a workshop titled Genetic Regulatory Network in Embryogenesis and Evaluation. Contents include the following: evolution of cleavage programs in relationship to axial specification and body plan evolution, changes in cell lineage specification elucidate evolutionary relations in spiralia, axial patterning in the leech: developmental mechanisms and evolutionary implications, hox genes in arthropod development and evolution, heterochronic genes in development and evolution, a common theme for LIM homeobox gene function across phylogeny, and mechanisms of specification in ascidian embryos.

Source record↗

Formation Flying Control of Multiple Spacecraft

The problem of coordination and control of multiple spacecraft (MS) moving in formation is considered. Here, each MS is modeled by a rigid body with fixed center of mass. First, various schemes for generating the desired formation patterns are discussed, Then, explicit control laws for formation-keeping and relative attitude alignment based on nearest neighbor-tracking are derived. The necessary data which must be communicated between the MS to achieve effective control are examined. The time-domain behavior of the feedback-controlled MS formation for typical low-Earth orbits is studied both analytically and via computer simulation. The paper concludes with a discussion of the implementation of the derived control laws, and the integration of the MS formation coordination and control system with a proposed inter-spacecraft communication/computing network.

Hadaegh, F. Y.↗

Bulk X-ray Doppler Velocities in the Supernova Remnant Cassiopeia A

We map the average line-of-sight velocities of the X-ray-emitting mass in the supernova remnant Cassiopeia A using measurements of the centroid of the Si-Healpha blend with the Advanced CCD Imaging Spectrometer on the Chandra X-Ray Observatory. This 4 inch scale map confirms the broad trends noted in previous studies, namely, that the line-of-sight velocity scale is roughly 2000-3000 kilometers per second with relatively more blueshifted material in the southeastern region of the remnant than in the northwest; new details are that the northwestern region consists of two arcs, with the southernmost one representing the most redshifted X-ray-emitting material in Cas A. These results are consistent with contemporaneous results from XMM-Newton. The X-ray patterns resemble the complex velocity patterns measured at optical wavelengths for much denser ejecta, and they support the growing body of evidence that the explosion and subsequent evolution of Cas A were highly asymmetrical.

Hwang, Una↗

On the Nature of Earth-Mars Porkchop Plots

Porkchop plots are a quick and convenient tool to help mission designers plan ballistic trajectories between two bodies. Parameter contours give rise to the familiar 'porkchop' shape. Each synodic period the pattern repeats, but not exactly, primarily due to differences in inclination and non-zero eccentricity. In this paper we examine the morphological features of Earth-to-Mars porkchop plots and the orbital characteristics that create them. These results are compared to idealistic and optimized transfers. Conclusions are drawn about 'good' opportunities versus 'bad' opportunities for different mission applications.

orbital parameters↗

Ankle and hip postural strategies defined by joint torques

Previous studies have identified two discrete strategies for the control of posture in the sagittal plane based on EMG activations, body kinematics, and ground reaction forces. The ankle strategy was characterized by body sway resembling a single-segment-inverted pendulum and was elicited on flat support surfaces. In contrast, the hip strategy was characterized by body sway resembling a double-segment inverted pendulum divided at the hip and was elicited on short or compliant support surfaces. However, biomechanical optimization models have suggested that hip strategy should be observed in response to fast translations on a flat surface also, provided the feet are constrained to remain in contact with the floor and the knee is constrained to remain straight. The purpose of this study was to examine the experimental evidence for hip strategy in postural responses to backward translations of a flat support surface and to determine whether analyses of joint torques would provide evidence for two separate postural strategies. Normal subjects standing on a flat support surface were translated backward with a range of velocities from fast (55 cm/s) to slow (5 cm/s). EMG activations and joint kinematics showed pattern changes consistent with previous experimental descriptions of mixed hip and ankle strategy with increasing platform velocity. Joint torque analyses revealed the addition of a hip flexor torque to the ankle plantarflexor torque during fast translations. This finding indicates the addition of hip strategy to ankle strategy to produce a continuum of postural responses. Hip torque without accompanying ankle torque (pure hip strategy) was not observed. Although postural control strategies have previously been defined by how the body moves, we conclude that joint torques, which indicate how body movements are produced, are useful in defining postural control strategies. These results also illustrate how the biomechanics of the body can transform discrete control patterns into a continuum of postural corrections.

Non-NASA Center↗

Population Accommodation for NASA Spacesuit and Hardware

The goal of this work is to review the population accommodation principles and methodologies NASA Johnson Space Center has developed for the spacesuit, vehicle hardware, and habitats. NASA has defined the target population characteristics in the Human-System Integration Requirements based on the US Army Anthropometric Survey (ANSUR) database. However, the data was screened to select the cases of 30-50 year old subjects, given the historical characteristics of the crew. Further, accommodation ranges were defined for critical body measurements, as NASA aims to accommodate 1st percentile female to 99th percentile male of the crew-like population. The historical truncation thresholds of 5-95th percentiles were not used. This ensured that the accommodation range was not limited and accounted for the current astronaut population. A simulation study also showed that less than 68% of the population may have remained after multiple measurement truncations due to the anthropometry covariance patterns if the narrower range was retained. The ranges were also adjusted for long-term trends of body shape changes as predicted by the US National Health and Nutrition Examination Survey. Overall, the requirements were deemed critical to ensure the fit and accommodation of the new suit and space hardware. The requirements have specifically defined boundary cases for verifications and validations, of which the details have proven useful as standards across the different space programs. The specific use and benefits will be further discussed through case studies at the presentation.

Han Kim↗

Results of Aerothermodynamic and Boundary-Layer Transition Testing of 0.0362-Scale X-38 (Rev. 3.1) Vehicle in NASA Langley 20-Inch Mach 6 Tunnel

The aeroheating characteristics of the X-38 Revision 3.1 lifting-body configuration have been experimentally examined in the Langley 20-inch Mach 6 Tunnel. Global surface heat transfer distributions, surface streamline patterns, and shock shapes were measured on a 0.0362-scale model of a proposed Space Station Crew Return Vehicle at Mach 6 in air. Parametric variations include angles-of-attack of 20 deg, 30 deg, and 40 deg; Reynolds numbers based on model length of 0.9 to 3.7 million; and body-flap deflections of O deg, 20 deg, 25 deg, and 30 deg. The effects of discrete roughness elements, which included trip height, location, size, and orientation, as well as multiple-trip parametrics, were investigated. This document is intended to serve as a quick release of preliminary data to the X-38 program; analysis is limited to observations of the experimental trends in order to expedite dissemination.

Berry, Scott A.↗

Peripheral modifications to the central drive for sweating.

Three subjects performed from 15 to 20 bouts of 10-min bicycle ergometer exercise in a 26 C ambient. The procedure imposed a consistent pattern of internal (esophageal) temperature increase in the presence of a constant mean skin temperature. Body weight loss was continuously recorded and rate of evaporative loss due to sweating was calculated during each minute of exercise. It was confirmed that both local and total sweating are functions of internal temperature at a fixed constant mean skin temperature. In the presence of a constant central drive for sweating, the sweating response could be modified at the periphery according to the area-specific characteristics and/or by local temperature.

Nadel, E. R.↗

An amphioxus nodal gene (AmphiNodal) with early symmetrical expression in the organizer and mesoderm and later asymmetrical expression associated with left-right axis formation

The full-length sequence and zygotic expression of an amphioxus nodal gene are described. Expression is first detected in the early gastrula just within the dorsal lip of the blastopore in a region of hypoblast that is probably comparable with the vertebrate Spemann's organizer. In the late gastrula and early neurula, expression remains bilaterally symmetrical, limited to paraxial mesoderm and immediately overlying regions of the neural plate. Later in the neurula stage, all neural expression disappears, and mesodermal expression disappears from the right side. All along the left side of the neurula, mesodermal expression spreads into the left side of the gut endoderm. Soon thereafter, all expression is down-regulated except near the anterior and posterior ends of the animal, where transcripts are still found in the mesoderm and endoderm on the left side. At this time, expression also begins in the ectoderm on the left side of the head, in the region where the mouth later forms. These results suggest that amphioxus and vertebrate nodal genes play evolutionarily conserved roles in establishing Spemann's organizer, patterning the mesoderm rostrocaudally and setting up the asymmetrical left-right axis of the body.

Non-NASA Center↗