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NASA NTRS2006

Advances in Pharmacotherapeutics of Space Motion Sickness

Space Motion Sickness (SMS) is common occurrence in the U.S. manned space flight program and nearly 2/3 of Shuttle crewmembers experience SMS. Several drugs have been prescribed for therapeutic management of SMS. Typically, orally-administered SMS medications (scopolamine, promethazine) have poor bioavailability and often have detrimental neurocognitive side effects at recommended doses. Intramuscularly administered promethazine (PMZ) is perceived to have optimal efficacy with minimal side effects in space. However, intramuscular injections are painful and the sedating neurocognitive side effects of promethazine, significant in controlled ground testing, may be masked in orbit because injections are usually given prior to crew sleep. Currently, EVAs cannot be performed by symptomatic crew or prior to flight day three due to the lack of a consistently efficacious drug, concern about neurocognitive side effects, and because an in-suit vomiting episode is potentially fatal. NASA has long sought a fast acting, consistently effective anti-motion sickness medication which has only minor neurocognitive side effects. Development of intranasal formulations of scopolamine and promethazine, the two commonly used SMS drugs at NASA for both space and reduced gravity environment medical operations, appears to be a logical alternative to current treatment modalities for SMS. The advantages are expected to be fast absorption, reliable and high bioavailability, and probably reduced neurocognitive side effects owing to dose reduction. Results from clinical trials with intranasal scopolamine gel formulation and pre-clinical testing of a prototype microcapsule intranasal gel dosage form of PMZ (INPMZ) will be discussed. These formulations are expected to offer a dependable and effective noninvasive treatment option for SMS.

Putcha, Lakshmi↗

NASA NTRS1991

Induced gravity Mars transportation systems configuration and hardware penalties

The need for an induced gravity environment in-transit to Mars is assessed based on current knowledge. Two possible alternatives to constant in-transit spinning, periodic spinning and Mars surface reconditioning are discussed and compared. Four propulsion options: cryogenic/aerobraking, solid core nuclear thermal, solar electric and nuclear electric are evaluated for concept adaptability to induced gravity, and salient differences from their microgravity counterparts are assessed. Configurations to the systems level are presented and accompanied by mass estimates. Hardware subsystems required for induced gravity vehicles, such as tether crawlers, tether reels, high-power roll-ring assemblies, etc., have been defined to a sufficient level of detail to confidently determine mass penalties. Results of this study show the mass penalties and complexity involved in producing an induced gravity environment.

Capps, Stephen↗

NASA NTRS2007

The ROSSI X-Ray Timing Explorer: Capabilities, Achievements and Aims

The prime scientific objectives of the Rossi X-Ray Timing Explorer (RXTE) were the study of astrophysical compact objects: black holes (galactic and extragalactic), many types of neutron stars, and accreting white dwarfs. RXTE was successful in achieving its original observing objectives of large area and high time resolution observations with broadband (2-200 keV) spectra, scheduled flexibly enough to enable observations of targets of opportunity on any timescale greater than a few hours. These capabilities enabled qualitatively new discoveries about dynamical timescale phenomena related to neutron stars and black holes, phenomena which probe basic physics in the most extreme environments of gravity, density, and magnetic fields. RXTE has extended its lifetime by applying the proportional counter area selectively and maintains schedule flexibility by making use of the distribution of targets around the sky. Proposed future observations emphasize opportunity to discover and study additional millisecond pulsars, pursue the high frequency quasi-periodic oscillations in black hole transients, and connect high frequency phenomena with longer term characteristics. RXTE will continue to strongly support, for both galactic and extragalactic targets, combining RXTE observations with other wavelengths (from IR to TeV) or with other capabilities, such as high spectral resolution.

Swank, J. H.↗

NASA NTRS1998

Internal Flows in Free Drops (IFFD)

Within the framework of an Earth-based research task investigating the internal flows within freely levitated drops, a low-gravity technology development experiment has been designed and carried out within the NASA Glovebox facility during the STS-83 and STS-94 Shuttle flights (MSL-1 mission). The goal was narrowly defined as the assessment of the capabilities of a resonant single-axis ultrasonic levitator to stably position free drops in the Shuttle environment with a precision required for the detailed measurement of internal flows. The results of this entirely crew-operated investigation indicate that the approach is fundamentally sound, but also that the ultimate stability of the positioning is highly dependent on the residual acceleration characteristic of the Spacecraft, and to a certain extent, on the initial drop deployment of the drop. The principal results are: the measured dependence of the residual drop rotation and equilibrium drop shape on the ultrasonic power level, the experimental evaluation of the typical drop translational stability in a realistic low-gravity environment, and the semi-quantitative evaluation of background internal flows within quasi-isothermal drops. Based on these results, we conclude that the successful design of a full-scale Microgravity experiment is possible, and would allow accurate the measurement of thermocapillary flows within transparent drops. The need has been demonstrated, however, for the capability for accurately deploying the drop, for a quiescent environment, and for precise mechanical adjustments of the levitator.

Trinh, E. H.↗

NASA NTRS1981

Avenues and incentives for commercial use of a low-gravity environment

The scientific and commercial utilization of the low-g environments for materials research and for process and product development is considered. Any products of commercial interest which necessitate processing in space will probably be low volume, high value items. To encourage the commercialization of materials processing in low-g, NASA, in parallel with establishing and demonstrating the scientific/technological precepts for analyzing and using a low-g environment, is establishing the legal and management mechanisms to share in the cost and risk of early commercial ventures, and is now working with commercial firms on a case-by basis to explore applications of this new technology to specific needs of the company.

Brown, R. L.↗

NASA NTRS1976

Zero-G processing of magnets experiment MA-070

Solidification of magnetic materials in the low gravity orbital environment was studied. The magnetic compounds under study, manganese bismuth and copper cobalt cerium ((Cu, Co)5Ce), both have the potential for the development of high coercive strength. Preliminary results indicate that static fluid configurations, in the absence of the gravitational body force, differ substantially from the documented terrestrial behavior. Chemical homogeneity is substantially enhanced on a macroscopic and microscopic level. Single crystal matrices have been grown in the coordinated growth regions of the flight samples. Primary crystals one order of magnitude greater than those grown terrestrially have been noted and are limited in size by the ampoule dimensions.

Larson, D. J., Jr.↗

NASA NTRS1989

Laser Welding in Space

Solidification type welding process experiments in conditions of microgravity were performed. The role of convection in such phenomena was examined and convective effects in the small volumes obtained in the laser weld zone were observed. Heat transfer within the weld was affected by acceleration level as indicated by the resulting microstructure changes in low gravity. All experiments were performed such that both high and low gravity welds occurred along the same weld beam, allowing the effects of gravity alone to be examined. Results indicate that laser welding in a space environment is feasible and can be safely performed IVA or EVA. Development of the hardware to perform the experiment in a Hitchhiker-g platform is recomended as the next step. This experiment provides NASA with a capable technology for welding needs in space. The resources required to perform this experiment aboard a Shuttle Hitchhiker-pallet are assessed. Over the four year period 1991 to 1994, it is recommended that the task will require 13.6 manyears and $914,900. In addition to demonstrating the technology and ferreting out the problems encountered, it is suggested that NASA will also have a useful laser materials processing facility for working with both the scientific and the engineering aspects of materials processing in space. Several concepts are also included for long-term optimization of available solar power through solar pumping solid state lasers directly for welding power.

Workman, Gary L.↗

NASA NTRS2013

Development and Testing of a Variable Conductance Thermal Acquisition, Transport, and Switching System

This paper describes the development and testing of a scalable thermal management architecture for instruments, subsystems, or systems that must operate in severe space environments with wide variations in sink temperature. The architecture involves a serial linkage of one or more hot-side variable conductance heat pipes (VCHPs) to one or more cold-side loop heat pipes (LHPs). The VCHPs provide wide area heat acquisition, limited distance thermal transport, modest against gravity pumping, concentrated LHP startup heating, and high switching ratio variable conductance operation. The LHPs provide localized heat acquisition, long distance thermal transport, significant against gravity pumping, and high switching ratio variable conductance operation. The single-VCHP, single-LHP system described herein was developed to maintain thermal control of a small robotic lunar lander throughout the lunar day-night thermal cycle. It is also applicable to other variable heat rejection space missions in severe environments. Operationally, despite a 60-70% gas blocked VCHP condenser during ON testing, the system was still able to provide 2-4 W/K ON conductance, 0.01 W/K OFF conductance, and an end-to-end switching ratio of 200-400. The paper provides a detailed analysis of VCHP condenser performance, which quantified the gas blockage situation. Future multi-VCHP/multi-LHP thermal management system concepts that provide power/transport length scalability are also discussed.

Bugby, David C.↗

NASA NTRS1972

A tunnel wick 100,000 watt-inch heat pipe.

The tunnel wick is a new type of heat pipe artery which can prime in a gravity environment by temperature-induced pressure differences between interior and exterior. The paper discusses the concept and its application in the design of room-temperature high-transport-capacity heat pipes. The analytical model of the system is summarized; and performance data obtained with the aid of a related computer program is included. Test data verifying the concept is presented for several pipes, including an eight-foot-long, 0.9-inch ID heat pipe, using ammonia working fluid, with a transport capacity in excess of 150,000 watt-inches. A brief discussion of potential applications for this type of heat pipe includes a variable conductance device to serve as a radiator header and a high capacity heat transport system.

Kosson, R.↗

NASA NTRS2010

Gravity-Off-loading System for Large-Displacement Ground Testing of Spacecraft Mechanisms

Gravity-off-loading of deployable spacecraft mechanisms during ground testing is a long-standing problem. Deployable structures which are usually too weak to support their own weight under gravity require a means of gravity-off-loading as they unfurl. Conventional solutions to this problem have been helium-filled balloons or mechanical pulley/counterweight systems. These approaches, however, suffer from the deleterious effects of added inertia or friction forces. The changing form factor of the deployable structure itself and the need to track the trajectory of the center of gravity also pose a challenge to these conventional technologies. This paper presents a novel testing apparatus for high-fidelity zero-gravity simulation for special application to deployable space structures such as solar arrays, magnetometer booms, and robotic arms in class 100,000 clean room environments

Han, Olyvia↗

NASA NTRS2017

Digital Cellular Solid Pressure Vessels: A Novel Approach for Human Habitation in Space

It is widely assumed that human exploration beyond Earth's orbit will require vehicles capable of providing long duration habitats that simulate an Earth-like environment - consistent artificial gravity, breathable atmosphere, and sufficient living space- while requiring the minimum possible launch mass. This paper examines how the qualities of digital cellular solids - high-performance, repairability, reconfigurability, tunable mechanical response - allow the accomplishment of long-duration habitat objectives at a fraction of the mass required for traditional structural technologies. To illustrate the impact digital cellular solids could make as a replacement to conventional habitat subsystems, we compare recent proposed deep space habitat structural systems with a digital cellular solids pressure vessel design that consists of a carbon fiber reinforced polymer (CFRP) digital cellular solid cylindrical framework that is lined with an ultra-high molecular weight polyethylene (UHMWPE) skin. We use the analytical treatment of a linear specific modulus scaling cellular solid to find the minimum mass pressure vessel for a structure and find that, for equivalent habitable volume and appropriate safety factors, the use of digital cellular solids provides clear methods for producing structures that are not only repairable and reconfigurable, but also higher performance than their conventionally manufactured counterparts.

Robotics↗

NASA NTRS1979

Commercialization of materials processing in space

The primary motivation of the Materials Processing in Space program is the scientific and commercial utilization of the effects of the unique environments of space on material processes. The reduction or elimination of the pervasive influences of gravity on Earth-based process mechanisms affords opportunities for understanding and improving ground-based processing or producing select materials in space which, typically, would be of low volume, high value commercial interest. Additionally, the unlimited, if not 'hard' vacuum of space affords equally interesting influences on material processes. To evolve the commercialization of Materials Processing in Space, the program seeks to establish and demonstrate the scientific/technological precepts for analyzing and using the space environment and, in parallel, to establish the legal and management mechanisms to implement commercial ventures.

Zoller, L. K.↗

NASA NTRS1999

Experimental Investigation of Pool Boiling Heat Transfer Enhancement in Microgravity in the Presence of Electric Fields

In boiling high heat fluxes are possible driven by relatively small temperature differences, which make its use increasingly attractive in aerospace applications. The objective of the research is to develop ways to overcome specific problems associated with boiling in the low gravity environment by substituting the buoyancy force with the electric force to enhance bubble removal from the heated surface. Previous studies indicate that in terrestrial applications nucleate boiling heat transfer can be increased by a factor of 50, as compared to values obtained for the same system without electric fields. The goal of our research is to experimentally explore the mechanisms responsible for EHD heat transfer enhancement in boiling in low gravity conditions, by visualizing the temperature distributions in the vicinity of the heated surface and around the bubble during boiling using real-time holographic interferometry (HI) combined with high-speed cinematography. In the first phase of the project the influence of the electric field on a single bubble is investigated. Pool boiling is simulated by injecting a single bubble through a nozzle into the subcooled liquid or into the thermal boundary layer developed along the flat heater surface. Since the exact location of bubble formation is known, the optical equipment can be aligned and focused accurately, which is an essential requirement for precision measurements of bubble shape, size and deformation, as well as the visualization of temperature fields by HI. The size of the bubble and the frequency of bubble departure can be controlled by suitable selection of nozzle diameter and mass flow rate of vapor. In this approach effects due to the presence of the electric field can be separated from effects caused by the temperature gradients in the thermal boundary layer. The influence of the thermal boundary layer can be investigated after activating the heater at a later stage of the research. For the visualization experiments a test cell was developed. All four vertical walls of the test cell are transparent, and they allow transillumination with laser light for visualization experiments by HI. The bottom electrode is a copper cylinder, which is electrically grounded. The copper block is heated with a resistive heater and it is equipped with 6 thermocouples that provide reference temperatures for the measurements with HI. The top electrode is a mesh electrode. Bubbles are injected with a syringe into the test cell through the bottom electrode. The working fluids presently used in the interferometric visualization experiments, water and PF 5052, satisfy requirements regarding thermophysical, optical and electrical properties. A 30kV power supply equipped with a voltmeter allows to apply the electric field to the electrodes during the experiments. The magnitude of the applied voltage can be adjusted either manually or through the LabVIEW data acquisition and control system connected to a PC. Temperatures of the heated block are recorded using type-T thermocouples, whose output is read by a data acquisition system. Images of the bubbles are recorded with 35mm photographic and 16mm high-speed cameras, scanned and analyzed using various software packages. Visualized temperature fields HI allows the visualization of temperature fields in the vicinity of bubbles during boiling in the form of fringes. Typical visualized temperature distributions around the air bubbles injected into the thermal boundary layer in PF5052 are shown. The temperature of the heated surface is 35 C. The temperature difference for a pair of fringes is approximately 0.05 C. The heat flux applied to the bottom surface is moderate, and the fringe patterns are regular. In the image a bubble penetrating the thermal boundary layer is visible. Because of the axial symmetry of the problem, simplified reconstruction techniques can be applied to recover the temperature field. The thermal plume developing above the heated surface for more intensive heating is shown. The temperature distribution in the liquid is clearly 3D, and tomographic techniques have to be applied to recover the temperature distribution in such a physical situation. A sequence of interferometric images showing the temperature distribution around the rising bubble, recorded with a high-speed camera is shown. Again, the temperature distribution is 3D, and a more complex approach to the evaluation, the tomographic reconstruction has to be taken. Measurement of the temperature distribution from the fringe pattern temperature distributions that yield important information regarding heat transfer are determined. Two algorithms that allow the quantitative evaluation of interferometric fringe patterns and the reconstruction of temperature fields during boiling have been developed at the Heat Transfer Laboratory of the Johns Hopkins University. In the first algorithm the bubble is assumed to be axially symmetrical, which significantly reduces the computational effort for quantifying the temperature distribution around the bubble. For this purpose the thermal boundary layer around the bubble is divided into equidistant concentric shells, and the refractive index is assumed to be constant in each of the shells. Since large temperature gradients are expected in the vicinity of the bubble during boiling, the deflection of the light beam cannot be neglected in boiling experiments. Since the exit angle of the light beam is known, this allows to account for the deflections and phase shifts outside the boundary layer (in the bulk fluid and in the windows of the test cell). Three dimensional temperature distributions in the vicinity of the bubble are reconstructed using tomographic techniques. In tomography, the measurement volume is sliced into 2D planes. In the present study these planes are parallel to the heated surface. The objective is to determine the values of the field parameter of interest in form of the field function in these 2D planes. The field parameter is the change of the refractive index of the liquid in the measurement volume caused by temperature changes. By superimposing data for many 2D planes recorded at the same time instant, the 3D temperature distribution in the measurement volume is recovered.

Herman, Cila↗

NASA NTRS2012

Reducing Extra-Terrestrial Excavation Forces with Percussion

High launch costs and mission requirements drive the need for low mass excavators with mobility platforms, which in turn have little traction and excavation reaction capacity in low gravity environments. This presents the need for precursor and long term future missions with low mass robotic mining technology to perform In-Situ Resource Utilization (ISRU) tasks. This paper discusses a series of experiments that investigate the effectiveness of a percussive digging device to reduce excavation loads and thereby the mass of the excavator itself. The goal of percussive excavation is to fluidize dry regolith in front of the leading edge of the tool by mechanically separating the microscopic interlocking grains resulting in a reduced force needed to shear the soil. There are several variables involved with this technique; this experiment varied: Impact energy, frequency, and excavation speed and held constant: impact direction, depth of cut, angle of tool, and soil bulk density. The test apparatus consisted of an aluminum truss bridge with a central pivoting arm. Attached to the arm was a winch with a load cell in line that recorded the tension in the cable and therefore the excavation load. The arm could be adjusted for excavation depth which was recorded along with the arm angle relative to the bridge. A percussive mechanism and 30" wide pivoting bucket were attached at the end of the arm simulating a basic backhoe with a percussion direction tangent to the direction of . movement. Internally the mechanism used a set of die springs and barrel cam to produce the percussive blow. By changing the springs and the speed of the motor the impact energy and frequency of percussion could be varied independently. Impact energies from 11.2J to 30.5J and frequencies from 0 BPM to 700 BPM were investigated. A reduction in excavation force of as much as 51% was achieved in this experimental investigation. Smaller percussive digging implements, tested by others, have achieved a reduction of as much as 72%. This paper will examine the effects of impact energy, frequency, scaling and their effect on excavation forces in a dry granular material such as lunar regolith. The past several years have shown an increasing interest in mining space resources both for exploration and commercial enterprises. This work studied the benefits and risks of percussive excavation and prelimin~ry results indicate that this technique may become an enabling technology for extra-terrestrial excavation of regolith and ice.

Schuler, Jason↗

NASA NTRS2012

Reducing Extra-Terrestrial Excavation Forces with Percussion

Mueller, Robert↗

NASA NTRS2018

The Need for Medical Geology in Space Exploration: Implications for the Journey to Mars and Beyond

The previous manned missions to the Moon represent milestones in human ingenuity, perseverance, and intellectual curiosity. They also highlight a major hazard for future human exploration of the Moon and beyond: surface dust. Not only did the dust cause mechanical and structural integrity issues with the suits, the dust "storm" generated upon reentrance into the crew cabin caused "lunar hay fever" and "almost blindness". It was further reported that the allergic response to the dust worsened with each exposure. The lower gravity environment exacerbated the exposure, requiring the astronauts to wear their helmet within the module in order to avoid breathing the irritating particles. Due to the prevalence of these high exposures, the Human Research Roadmap developed by NASA identifies the Risk of Adverse Health and Performance Effects of Celestial Dust Exposure as an area of concern. Extended human exploration will further increase the probability of inadvertent and repeated exposures to celestial dusts. Going forward, hazard assessments of celestial dusts will be determined through sample return efforts prior to astronaut deployment. However, even then the returned samples could also put the Curators, technicians, and scientists at risk during processing and examination.

Harrington, A. D.↗

NASA NTRS1999

Thermophysical Property Measurements of Molten Semiconductors in 1-g and Reduced-g Condition

Understanding and controlling the formation kinetics of varieties of crystal imperfections such as point defects, non uniform distribution of doping atoms, and impurity atoms in growing crystals are very important. Theoretical (numerical) modeling of the crystal growth process is an essential step to achieving these objectives. In order to obtain reliable modeling results, input parameters, i.e. various thermophysical parameters, must be accurate. The importance of accurate thermophysical properties of semiconductors in crystal growth cannot be overly emphasized. The total hemispherical emissivity, for instance, has a dramatic impact on the thermal environment. It determines the radiative emission from the surface of the melt which determines to a large extent the profile of the solidified crystal. In order to understand the convection and the turbulence in a melt, viscosity becomes an important parameter. The liquid surface tension determines the shape of the liquid-atmosphere interface near the solid-liquid-atmosphere triple point. Currently used values for these parameters are rather inaccurate, and this program intends to provide more reliable measurements of these thermophysical properties. Thus, the objective of this program is in the accurate measurements of various thermophysical properties which can be reliably used in the modeling of various crystal growth processes. In this program, thermophysical properties of molten semiconductors, such as Si, Ge, Si-Ge, and InSb will be measured as a function of temperature using the High Temperature Electrostatic Levitator at JPL. Each material will be doped by different kinds of impurities at various doping levels. Thermophysical properties which will be measured include: density, thermal expansion coefficient, surface tension, viscosity, specific heat, hemispherical total emissivity, and perhaps electrical and thermal conductivities. Many molten semiconductors are chemically reactive with crucibles. As a result, these dispersed impurities in the melts tend to substantially modify the properties of pure semiconductors. Sample levitation done in a vacuum clearly helps maintain the sample purity. However, in the 1-g environment, all gravity caused effects such as convection, sedimentation and buoyancy are still present in the sample. In addition, large forces needed to levitate a sample in the presence of the gravity can cause additional flows in the melt. The use of the High Temperature Electrostatic Levitator (HTESL) for the present research is a recent development and little is known about the flows induced by the electrostatic forces. In this ground base program, we will define the limits of HTESL technology as various thermophysical properties of molten semiconductors are measured.

Rhim, Won-Kyu↗

NASA NTRS2005

Jumping in simulated and true microgravity: response to maximal efforts with three landing types

BACKGROUND: Exercise is a promising countermeasure to the physiological deconditioning experienced in microgravity, but has not proven effective in eliminating the ongoing loss of bone mineral, most likely due to the lack of high-impact forces and loading rates during in-flight activity. We wanted to determine lower-extremity response to high-impact jumping exercises in true and simulated microgravity and establish if 1-G force magnitudes can be achieved in a weightless environment. METHODS: Jumping experiments were performed in a ground-based zero-gravity simulator (ZGS) in 1 G, and during parabolic flight with a gravity-replacement system. There were 12 subjects who participated in the study, with 4 subjects common to both conditions. Force, loading rates, jump height, and kinematics were analyzed during jumps with three distinct landings: two-footed toe-heel, one-footed toe-heel, and flat-footed. Gravity replacement loads of 45%, 60%, 75%, and 100% bodyweight were used in the ZGS; because of time constraints, these loads were limited to 60% and 75% bodyweight in parabolic flight. RESULTS: Average peak ground-reaction forces during landing ranged between 1902+/-607 and 2631+/-663 N in the ZGS and between 1683+/-807 and 2683+/-1174 N in the KC-135. No significant differences were found between the simulated and true microgravity conditions, but neither condition achieved the magnitudes found in 1 G. CONCLUSION: Data support the hypothesis that jumping exercises can impart high-impact forces during weightlessness and that the custom-designed ZGS will replicate what is experienced in true microgravity.

short duration↗