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NASA NTRS1985

Crystal growth of device quality GaAs in space

The present program has been aimed at solving the fundamental and technological problems associated with Crystal Growth of Device Quality in Space. The initial stage of the program was devoted strictly to ground-based research. The unsolved problems associated with the growth of bulk GaAs in the presence of gravitational forces were explored. Reliable chemical, structural and electronic characterization methods were developed which would permit the direct relation of the salient materials parameters (particularly those affected by zero gravity conditions) to the electronic characteristics of single crystal GaAs, in turn to device performance. These relationships are essential for the development of optimum approaches and techniques. It was concluded that the findings on elemental semiconductors Ge and Si regarding crystal growth, segregation, chemical composition, defect interactions, and materials properties-electronic properties relationships are not necessarily applicable to GaAs (and to other semiconductor compounds). In many instances totally unexpected relationships were found to prevail.

Gatos, H. C.↗

NASA NTRS1991

Macular bioaccelerometers on earth and in space

Spaceflight offers the unique opportunity to study linear bioaccelerometers (vestibular maculas) in the virtual absence of a primary stimulus, gravitational acceleration. Combined morphological-physiological studies of maculas fixed in space and following flight should reveal macular adaptive responses to microgravity, and their time-course. Ground-based research, already begun, using computer-assisted, three-dimensional reconstructions of macular terminal fields will lead to development of computer models of functioning maculas. This research should continue in conjunction with physiological studies, including work with multichannel electrodes.

Ross, M. D.↗

NASA NTRS2010

LISA and LISA Pathfinder: Gravitational Wave Observation in Space

The Laser Interferometer Space Antenna (LISA) is a planned NASA-ESA gravitational wave observatory in the frequency range of 0.1 mHz--100 mHz. This observation band is inaccessible to ground-based detectors due to fluctuations in the Earth gravitational field. Gravitational wave sources for LISA include galactic binaries, mergers of supermassive black-hole binaries, extreme-mass-ratio inspirals, and cosmology backgrounds and bursts. LISA is a constellation of three spacecraft separated by 5 million km in an equilateral triangle, whose center follows the Earth in a heliocentric orbit with an orbital phase offset of 20 degrees. Challenging technology is required to ensure pure geodetic trajectories of the six onboard test masses, whose distance fluctuations will be measured by interspacecraft laser interferometers with picometer accuracy. LISA Pathfinder is an ESA-launched technology demonstration mission of key LISA subsystems such as spacecraft control with micronewton thrusters, test mass drag-free control, and precision laser interferometry between free-flying test masses. Ground testing of hardware of the Gravitational Reference Sensor and Optical Metrology subsystems of LISA Pathfinder is currently ongoing. A detailed description of the two missions and an overview of current investigations conducted by the community will be discussed. The current status in development and implementation of LISA Pathfinder pre-flight systems and latest results of the ongoing ground testing efforts will also be presented.

Guzman, Felipe↗

NASA NTRS2010

Laser Interferometry for Gravitational Wave Observation: LISA and LISA Pathfinder

The Laser Interferometer Space Antenna (LISA) is a planned NASA-ESA gravitational wave observatory in the frequency range of 0.1mHz-100mHz. This observation band is inaccessible to ground-based detectors due to the large ground motions of the Earth. Gravitational wave sources for LISA include galactic binaries, mergers of supermasive black-hole binaries, extreme-mass-ratio inspirals, and possibly from as yet unimagined sources. LISA is a constellation of three spacecraft separated by 5 million km in an equilateral triangle, whose center follows the Earth in a heliocentric orbit with an orbital phase offset oF 20 degrees. Challenging technology is required to ensure pure geodetic trajectories of the six onboard test masses, whose distance fluctuations will be measured by interspacecraft laser interferometers with picometer accuracy. LISA Pathfinder is an ESA-launched technology demonstration mission of key LISA subsystems such us spacecraft control with micro-newton thrusters, test mass drag-free control, and precision laser interferometry between free-flying test masses. Ground testing of flight hardware of the Gravitational Reference Sensor and Optical Metrology subsystems of LISA Pathfinder is currently ongoing. An introduction to laser interferometric gravitational wave detection, ground-based observatories, and a detailed description of the two missions together with an overview of current investigations conducted by the community will bc discussed. The current status in development and implementation of LISA Pathfinder pre-flight systems and latest results of the ongoing ground testing efforts will also be presented

Guzman, Felipe↗

NASA NTRS2011

Kinematics and Kinetics of Squat and Deadlift Exercises with Varying Stance Widths

The primary motion of squat and deadlift exercise involves flexion and extension of the hips, knees, and ankles, but each exercise can be performed with variations in stance width. These variations may result in differing kinematics and ground reaction forces (GRF), which may in turn affect joint loading. PURPOSE: The purpose of this investigation was to compare ankle, knee, and hip kinematics and kinetics of normal squat (NS), wide-stance squat (WS), normal deadlift (ND), and sumo deadlift (SD). We hypothesized that hip joint kinematics and work at each joint would differ between exercise variations. METHODS: Six subjects (3 m/3 f; 70.0 plus or minus 13.7 kg; 168 plus or minus 9.9 cm) performed each lift in normal gravity on the ground-based version of the Advanced Resistive Exercise Device (ARED) used on the International Space Station. The ARED provided resistance with a combination vacuum tube/flywheel mechanism designed to replicate the gravitational and inertial forces of free weights. Subjects completed each lift with their 10-repetition maximum load. Kinematic data were collected at 250 Hz by a 12-camera motion-capture system (Smart-D, BTS Bioengineering, Milan, Italy), and GRF data were collected at 1000 Hz with independent force platforms for each leg (Model 9261, Kistler Instruments AG, Winterhur, Switzerland). All data were captured simultaneously on a single workstation. The right leg of a single lift for each motion was analyzed. Modeling software (OpenSim 2.2.0, Simbios, Palo Alto, CA) determined joint kinematics and net positive and negative work at each lower extremity joint. Total work was found as the sum of work across all joints and was normalized by system mass. Effect sizes and their 95% confidence intervals were computed between conditions. RESULTS: Peak GRF were similar for each lift. There were no differences between conditions in hip flexion range of motion (ROM). For hip adduction ROM, there were no differences between the NS, WS, and SD. However, hip adduction ROM was greater during the NS and SD than during the ND. Hip rotation ROM was greater during the WS than during the NS and SD, and was greater during the SD than during the ND. For knee and ankle flexion ROM, the ND, WS, and SD were not different, but ROM was greater during the NS than the ND and greater during the WS than the SD. Total eccentric work was greater during the WS than the SD. Otherwise, there were no differences in eccentric or concentric work between conditions. CONCLUSIONS: Although squat and deadlift exercises consist of similar motions, there are kinematic differences between them that depend on stance width. Total eccentric and concentric work are similar for different lifts, but differing kinematics may require activation of different musculature for each variation. With respect to each condition, in the ND the ROM of each joint tended to be less, and the WS tended to trade knee motion for hip motion. PRACTICAL APPLICATIONS: Knowledge of differences in kinematics and kinetics between different squat and deadlift variations is important for coaches and rehabilitation personnel to understand when prescribing exercise. Our results suggest that each variation of the squat and deadlift should be considered a separate exercise that may induce different long-term training effects.

DeWitt, John K.↗

NASA NTRS2013

Satellite Remote Sensing: Aerosol Measurements

Aerosols are solid or liquid particles suspended in the air, and those observed by satellite remote sensing are typically between about 0.05 and 10 microns in size. (Note that in traditional aerosol science, the term "aerosol" refers to both the particles and the medium in which they reside, whereas for remote sensing, the term commonly refers to the particles only. In this article, we adopt the remote-sensing definition.) They originate from a great diversity of sources, such as wildfires, volcanoes, soils and desert sands, breaking waves, natural biological activity, agricultural burning, cement production, and fossil fuel combustion. They typically remain in the atmosphere from several days to a week or more, and some travel great distances before returning to Earth's surface via gravitational settling or washout by precipitation. Many aerosol sources exhibit strong seasonal variability, and most experience inter-annual fluctuations. As such, the frequent, global coverage that space-based aerosol remote-sensing instruments can provide is making increasingly important contributions to regional and larger-scale aerosol studies.

Kahn, Ralph A.↗

NASA NTRS1988

The dynamics of free liquid drops

The behavior of rotating and oscillating free liquid drops was studied by many investigators theoretically for many years. More recent numerical treatments have yielded predictions which are yet to be verified experimentally. The purpose is to report the results of laboratory work as well as that of the experiments carried out in space during the flight of Spacelab 3, and to compare it with the existing theoretical studies. Ground-based experiments were attempted as a first approximation to the ideal boundary conditions used by the theoretical treatments by neutralizing the overwhelming effects of the Earth's gravitational field with an outside supporting liquid and with the use of levitation technology. The viscous and inertial loading of such a suspending fluid was found to profoundly effect the results, but the information thus gathered has emphasized the uniqueness of the experimental data obtained in the low-gravity environment of space.

Wang, T. G.↗

NASA NTRS1992

On the use of Space Station Freedom in support of the SEI - Life science research

The use of the Space Station Freedom (SSF) for life sciences research is evaluated from the standpoint of requirements for the Space Exploration Initiative (SEI). SEI life sciences research encompasses: (1) biological growth and development in space; (2) life support and environmental health; (3) physiological/psychological factors of extended space travel; and (4) space environmental factors. The platforms required to support useful study in these areas are listed and include ground-based facilities, permanently manned spacecraft, and the Space Shuttle. The SSF is shown to be particularly applicable to the areas of research because its facilities can permit the study of gravitational biology, life-support systems, and crew health. The SSF can serve as an experimental vehicle to derive the required knowledge needed to establish a commitment to manned Mars missions and colonization plans.

Leath, K.↗

NASA NTRS1979

Materials processing - A matter of gravity

The paper examines the pervasive influences of gravitational forces on processes used in the preparation of materials employed in earth-based applications and considers the knowledge and benefits which may be derived from the microgravity environment of space in improving upon these constraints. Particular attention is given to the NASA Materials Processing in Space program, which is focused on crystal growth processes, solidification processes, containerless processing, fluid and chemical processes, and bioseparation processes.

Zoller, L. K.↗

NASA NTRS2016

NASA's Aerosol Sampling Experiment Summary

In a spacecraft cabin environment, the size range of indoor aerosols is much larger and they persist longer than on Earth because they are not removed by gravitational settling. A previous aerosol experiment in 1991 documented that over 90 of the mass concentration of particles in the NASA Space Shuttle air were between 10 m and 100 m based on measurements with a multi-stage virtual impactor and a nephelometer (Liu et al. 1991). While the now-retired Space Shuttle had short duration missions (less than two weeks), the International Space Station (ISS) has been continually inhabited by astronauts for over a decade. High concentrations of inhalable particles on ISS are potentially responsible for crew complaints of respiratory and eye irritation and comments about 'dusty' air. Air filtration is the current control strategy for airborne particles on the ISS, and filtration modeling, performed for engineering and design validation of the air revitalization system in ISS, predicted that PM requirements would be met. However, aerosol monitoring has never been performed on the ISS to verify PM levels. A flight experiment is in preparation which will provide data on particulate matter in ISS ambient air. Particles will be collected with a thermophoretic sampler as well as with passive samplers which will extend the particle size range of sampling. Samples will be returned to Earth for chemical and microscopic analyses, providing the first aerosol data for ISS ambient air.

Thermophoretic sampler↗

NASA NTRS2016

Sampling Indoor Aerosols on the International Space Station

Thermophoretic sampler↗

NASA NTRS1992

Telescopes for a lunar outpost

This paper presents an overview of lunar-based telescopes. It begins with a review of the impressive attributes of the moon for astronomy which include a hard vacuum, seismic stability, low gravitational field, large surface area, dark and radio-quiet skies on the far-side, cold craters at the poles, and an abundance of raw materials. These attributes, coupled with the availability of technicians at a lunar outpost, make the moon the most attractive site for the next generation of space-based observatories. It is argued that modest, light-weight instruments such a generic 1-m optical/UV/IR telescope and a low radio frequency phased array are well suited for early deployment on the moon. More advanced concepts such as a 16-m filled aperture telescope and an optical interferometer will make unprecedented strides in sensitivity and resolution. Although complex, such telescopes are well-suited to an evolutionary construction and deployment scheme.

Burns, Jack O.↗

NASA NTRS1992

Opportunities for research on Space Station Freedom

NASA has allocated research accommodations on Freedom (equipment, utilities, etc.) to the program offices that sponsor space-based research and development as follows: Space Science and Applications (OSSA)--52 percent, Commercial Programs (OCP)--28 percent, Aeronautics and Space Technology (OAST)--12 percent, and Space Flight (OSF)--8 percent. Most of OSSA's allocation will be used for microgravity and life science experiments; although OSSA's space physics, astrophysics, earth science and applications, and solar system exploration divisions also will use some of this allocation. Other Federal agencies have expressed an interest in using Space Station Freedom. They include the National Institutes of Health (NIH), U.S. Geological Survey, National Science Foundation, National Oceanic and Atmospheric Administration, and U.S. Departments of Agriculture and Energy. Payload interfaces with space station lab support equipment must be simple, and experiment packages must be highly contained. Freedom's research facilities will feature International Standard Payload Racks (ISPR's), experiment racks that are about twice the size of a Spacelab rack. ESA's Columbus lab will feature 20 racks, the U.S. lab will have 12 racks, and the Japanese lab will have 10. Thus, Freedom will have a total of 42 racks versus 8 for Space lab. NASA is considering outfitting some rack space to accommodate small, self-contained payloads similar to the Get-Away-Special canisters and middeck-locker experiment packages flown on Space Shuttle missions. Crew time allotted to experiments on Freedom at permanently occupied capability will average 25 minutes per rack per day, compared to six hours per rack per day on Spacelab missions. Hence, telescience--the remote operation of space-based experiments by researchers on the ground--will play a very important role in space station research. Plans for supporting life sciences research on Freedom focus on the two basic goals of NASA 's space life sciences program: to ensure the health, safety, and productivity of humans in space and to acquire fundamental knowledge of biological processes. Space-based research has already shown that people and plants respond the same way to the microgravity environment: they lose structure. However, the mechanisms by which they respond are different, and researchers do not yet know much about these mechanisms. Life science research accommodations on Freedom will include facilities for experiments designed to address this and other questions, in fields such as gravitational biology, space physiology, and biomedical monitoring and countermeasures research.

Phillips, Robert W.↗

NASA NTRS1989

Do the design concepts used for the space flight hardware directly affect cell structure and/or cell function ground based simulations

The use of clinostats and centrifuges to explore the hypogravity range between zero and 1 g is described. Different types of clinostat configurations and clinostat-centrifuge combinations are compared. Some examples selected from the literature and current research in gravitational physiology are presented to show plant responses in the simulated hypogravity region of the g-parameter (0 is greater than g is greater than 1). The validation of clinostat simulation is discussed. Examples in which flight data can be compared to clinostat data are presented. The data from 3 different laboratories using 3 different plant species indicate that clinostat simulation in some cases were qualitatively similar to flight data, but that in all cases were quantitatively different. The need to conduct additional tests in weightlessness is emphasized.

Chapman, David K.↗

NASA NTRS1990

Convection phenomena in low-gravity processing - The GTE GaAs space experiment

A numerical model for the proposed GTE GaAs space experiment is presented. The model includes the actual ampule design and the experimentally obtained furnace thermal profiles. Results are presented based on both the traditional steady-state models and on fully time dependent simulations. It is demonstrated that the commonly presumed axisymmetric flows in numerical studies are physically accurate only when the local gravitational acceleration vector is parallel to the ampules's axis. Other gravitational orientations result in nontrivial three-dimensional flows which must be resolved using full three-dimensional models. Implications of the resulting flow and thermal fields on the growing crystal at conditions available during space processing are also discussed.

Arnold, W. A.↗

NASA NTRS1992

How shall we go to Mars? A review of mission scenarios

Four scenarios for initial Mars missions are examined in this overview of strategies. The scenarios are compared to determine the most effective option with respect to the effects of reduced gravity, exposure to space radiation, and cost. Mission cost is evaluated based on initial mass in earth orbit for the four mission types: classes-opposition, conjunction, fast-transfer conjunction, and split sprint. The reduced gravitational force on the Martian surface is considered to be a critical factor because the physical deconditioning at 3/8 earth gravity is assumed to approximate that of zero gravity. Exposure to radiation is not determined to be a definite discriminator because none of the scenarios exceed established limits. The split sprint is championed based on the high energy transfers considered and with chemical propulsion (or preferably nuclear thermal propulsion) and aerobraking.

Walberg, Gerald↗

NASA NTRS2003

Focused Assessment with Sonography for Trauma in weightlessness: a feasibility study

BACKGROUND: The Focused Assessment with Sonography for Trauma (FAST) examines for fluid in gravitationally dependent regions. There is no prior experience with this technique in weightlessness, such as on the International Space Station, where sonography is currently the only diagnostic imaging tool. STUDY DESIGN: A ground-based (1 g) porcine model for sonography was developed. We examined both the feasibility and the comparative performance of the FAST examination in parabolic flight. Sonographic detection and fluid behavior were evaluated in four animals during alternating weightlessness (0 g) and hypergravity (1.8 g) periods. During flight, boluses of fluid were incrementally introduced into the peritoneal cavity. Standardized sonographic windows were recorded. Postflight, the video recordings were divided into 169 20-second segments for subsequent interpretation by 12 blinded ultrasonography experts. Reviewers first decided whether a video segment was of sufficient diagnostic quality to analyze (determinate). Determinate segments were then analyzed as containing or not containing fluid. A probit regression model compared the probability of a positive fluid diagnosis to actual fluid levels (0 to 500 mL) under both 0-g and 1.8-g conditions. RESULTS: The in-flight sonographers found real-time scanning and interpretation technically similar to that of terrestrial conditions, as long as restraint was maintained. On blinded review, 80% of the recorded ultrasound segments were considered determinate. The best sensitivity for diagnosis in 0 g was found to be from the subhepatic space, with probability of a positive fluid diagnosis ranging from 9% (no fluid) to 51% (500 mL fluid). CONCLUSIONS: The FAST examination is technically feasible in weightlessness, and merits operational consideration for clinical contingencies in space.

NASA Discipline Life Sciences Technologies↗

NASA NTRS1996

Gravitational physiology of human immune cells: a review of in vivo, ex vivo and in vitro studies

The study of the function of immune cells in microgravity has been studied for more than 20 years in several laboratories. It is clear today that the immune system is depressed in more than 50% of the astronauts during and after space flight and that the activation of T lymphocytes by mitogens in vitro changes dramatically. This article gives an overview of the gravitational studies conducted by our laboratory in Spacelab, in MIR station, in sounding rockets and on the ground in the clinostat and the centrifuge. Three experimental approaches are followed in our work: (i) Ex vivo studies are performed with blood samples drawn from astronauts; (ii) in vivo studies are based on the application of seven antigens to the skin of the astronauts; (iii) in vitro studies are carried out with immune cells purified from the blood of healthy donors (not astronauts). The data from our in vivo and ex vivo studies are in agreement with those of other laboratories and show that the immunological function is depressed in the majority of astronauts as a consequence of the stress of space flight rather than by a direct influence of gravity on the cell. Immune depression may become a critical hazard on long duration flights on space stations or to other planets. In vitro experiments show that cultures of free-floating lymphocytes and monocytes undergo a dramatic depression of activation by the mitogen concanavalin A, while activation is more than doubled when the cells are attached to microcarrier beads. Such effects may be attributed to both direct and indirect effects of gravitational unloading on basic biological mechanisms of the cell. While the in vitro data are very important to clarify certain aspects of the biological mechanism of T cells activation, they are not descriptive of the changes of the immunological function of the astronauts.

Review↗