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At least 199 records · Page 11

Measurement of Recoil Losses and Ranges for Spallation Products Produced in Proton Interactions with Al, Si, Mg at 200 and 500 MeV

Cosmic rays interact with extraterrestrial materials to produce a variety of spallation products. If these cosmogenic nuclides are produced within an inclusion in such material, then an important consideration is the loss of the product nuclei, which recoil out of the inclusion. Of course, at the same time, some atoms of the product nuclei under study may be knocked into the inclusion from the surrounding material, which is likely to have a different composition to that of the inclusion [1]. For example, Ne-21 would be produced in presolar grains, such as SiC, when irradiated in interstellar space. However, to calculate a presolar age, one needs to know how much 21Ne is retained in the grain. For small grains, the recoil losses might be large [2, 3] To study this effect under laboratory conditions, recoil measurements were made using protons with energies from 66 - 1600 MeV on Si, Al and Ba targets [3, 4, 5].

Sisterson, J. M.↗

NBS1 knockdown by small interfering RNA increases ionizing radiation mutagenesis and telomere association in human cells

Hypomorphic mutations which lead to decreased function of the NBS1 gene are responsible for Nijmegen breakage syndrome, a rare autosomal recessive hereditary disorder that imparts an increased predisposition to development of malignancy. The NBS1 protein is a component of the MRE11/RAD50/NBS1 complex that plays a critical role in cellular responses to DNA damage and the maintenance of chromosomal integrity. Using small interfering RNA transfection, we have knocked down NBS1 protein levels and analyzed relevant phenotypes in two closely related human lymphoblastoid cell lines with different p53 status, namely wild-type TK6 and mutated WTK1. Both TK6 and WTK1 cells showed an increased level of ionizing radiation-induced mutation at the TK and HPRT loci, impaired phosphorylation of H2AX (gamma-H2AX), and impaired activation of the cell cycle checkpoint regulating kinase, Chk2. In TK6 cells, ionizing radiation-induced accumulation of p53/p21 and apoptosis were reduced. There was a differential response to ionizing radiation-induced cell killing between TK6 and WTK1 cells after NBS1 knockdown; TK6 cells were more resistant to killing, whereas WTK1 cells were more sensitive. NBS1 deficiency also resulted in a significant increase in telomere association that was independent of radiation exposure and p53 status. Our results provide the first experimental evidence that NBS1 deficiency in human cells leads to hypermutability and telomere associations, phenotypes that may contribute to the cancer predisposition seen among patients with this disease.

Non-NASA Center↗

Harnessing the Power of the Sun

The Environmental Research Aircraft and Sensor Technology (ERAST) Alliance was created in 1994 and operated for 9 years as a NASA-sponsored coalition of 28 members from small companies, government, universities, and nonprofit organizations. ERAST s goal was to foster development of remotely piloted aircraft technology for scientific, humanitarian, and commercial purposes. Some of the aircraft in the ERAST Alliance were intended to fly unmanned at high altitudes for days at a time, and flying for such durations required alternative sources of power that did not add weight. The most successful solution for this type of sustained flight is the lightest solar energy. Photovoltaic cells convert sunlight directly into electricity. They are made of semi-conducting materials similar to those used in computer chips. When sunlight is absorbed, electrons are knocked loose from their atoms, allowing electricity to flow. Under the ERAST Alliance, two solar-powered technology demonstration aircraft, Pathfinder and Helios, were developed. Pathfinder is a lightweight, remotely piloted flying wing aircraft that demonstrated the technology of applying solar cells for long-duration, high-altitude flight. Solar arrays covering most of the upper wing surface provide power for the aircraft s electric motors, avionics, communications, and other electronic systems. Pathfinder also has a backup battery system that can provide power for between 2 and 5 hours to allow limited-duration flight after dark. It was designed, built, and operated by AeroVironment, Inc., of Monrovia, California. On September 11, 1995, Pathfinder reached an altitude of 50,500 feet, setting a new altitude record for solar-powered aircraft. The National Aeronautic Association presented the NASA-industry team with an award for 1 of the 10 Most Memorable Record Flights of 1995.

Source record↗

Electron Impact Ionization: A New Parameterization for 100 eV to 1 MeV Electrons

Low, medium and high energy electrons can penetrate to the thermosphere (90-400 km; 55-240 miles) and mesosphere (50-90 km; 30-55 miles). These precipitating electrons ionize that region of the atmosphere, creating positively charged atoms and molecules and knocking off other negatively charged electrons. The precipitating electrons also create nitrogen-containing compounds along with other constituents. Since the electron precipitation amounts change within minutes, it is necessary to have a rapid method of computing the ionization and production of nitrogen-containing compounds for inclusion in computationally-demanding global models. A new methodology has been developed, which has parameterized a more detailed model computation of the ionizing impact of precipitating electrons over the very large range of 100 eV up to 1,000,000 eV. This new parameterization method is more accurate than a previous parameterization scheme, when compared with the more detailed model computation. Global models at the National Center for Atmospheric Research will use this new parameterization method in the near future.

Fang, Xiaohua↗

Evaluation of Margins of Safety in Brazed Joints

One of the essential steps in assuring reliable performance of high cost critical brazed structures is the assessment of the Margin of Safety (MS) of the brazed joints. In many cases the experimental determination of the failure loads by destructive testing of the brazed assembly is not practical and cost prohibitive. In such cases the evaluation of the MS is performed analytically by comparing the maximum design loads with the allowable ones and incorporating various safety or knock down factors imposed by the customer. Unfortunately, an industry standard methodology for the design and analysis of brazed joints has not been developed. This paper provides an example of an approach that was used to analyze an AlBeMet 162 (38%Be-62%Al) structure brazed with the AWS BAlSi-4 (Al-12%Si) filler metal. A practical and conservative interaction equation combining shear and tensile allowables was developed and validated to evaluate an acceptable (safe) combination of tensile and shear stresses acting in the brazed joint. These allowables are obtained from testing of standard tensile and lap shear brazed specimens. The proposed equation enables the assessment of the load carrying capability of complex brazed joints subjected to multi-axial loading.

Flom, Yury↗

Minimum Specific Fuel Consumption of a Liquid-Cooled Multicylinder Aircraft Engine as Affected by Compression Ratio and Engine Operating Conditions

An investigation was conducted on a 12-cylinder V-type liquid-cooled aircraft engine of 1710-cubic-inch displacement to determine the minimum specific fuel consumption at constant cruising engine speed and compression ratios of 6.65, 7.93, and 9.68. At each compression ratio, the effect.of the following variables was investigated at manifold pressures of 28, 34, 40, and 50 inches of mercury absolute: temperature of the inlet-air to the auxiliary-stage supercharger, fuel-air ratio, and spark advance. Standard sea-level atmospheric pressure was maintained at the auxiliary-stage supercharger inlet and the exhaust pressure was atmospheric. Advancing the spark timing from 34 deg and 28 deg B.T.C. (exhaust and intake, respectively) to 42 deg and 36 deg B.T.C. at a compression ratio of 6.65 resulted in a decrease of approximately 3 percent in brake specific fuel consumption. Further decreases in brake specific fuel consumption of 10.5 to 14.1 percent (depending on power level) were observed as the compression ratio was increased from 6.65 to 9.68, maintaining at each compression ratio the spark advance required for maximum torque at a fuel-air ratio of 0.06. This increase in compression ratio with a power output of 0.585 horsepower per cubic inch required a change from . a fuel- lend of 6-percent triptane with 94-percent 68--R fuel at a compression ratio of 6.65 to a fuel blend of 58-percent, triptane with 42-percent 28-R fuel at a compression ratio of 9.68 to provide for knock-free engine operation. As an aid in the evaluation of engine mechanical endurance, peak cylinder pressures were measured on a single-cylinder engine at several operating conditions. Peak cylinder pressures of 1900 pounds per square inch can be expected at a compression ratio of 9.68 and an indicated mean effective pressure of 320 pounds per square inch. The engine durability was considerably reduced at these conditions.

Brun, Rinaldo J.↗

High LET Radiation Can Enhance TGF(Beta) Induced EMT and Cross-Talk with ATM Pathways

The TGF(Beta) pathway has been shown to regulate or directly interact with the ATM pathway in the response to radiation in mammary epithelial cells. We investigated possible interactions between the TGF(Beta) and ATM pathways following simulated space radiation using hTERT immortalized human esophageal epithelial cells (EPC-hTERT), mink lung epithelial cells (Mv1lu), and several human fibroblast cell lines. TGF(Beta) is a key modulator of the Epithelial-Mesenchymal Transition (EMT), important in cancer progression and metastasis. The implication of EMT by radiation also has several lines of developing evidence, however is poorly understood. The identification of TGF(Beta) induced EMT can be shown in changes to morphology, related gene over expression or down regulation, which can be detected by RT-PCR, and immunostaining and western blotting. In this study, we have observed morphologic and molecular alternations consistent with EMT after Mv1lu cells were treated with TGF(Beta) High LET radiation enhanced TGF(Beta) mediated EMT with a dose as low as 0.1Gy. In order to consider the TGF(Beta) interaction with ATM we used a potent ATM inhibitor Ku55933 and investigated gene expression changes and Smad signaling kinetics. Ku559933 was observed to reverse TGF(Beta) induced EMT, while this was not observed in dual treated cells (radiation+TGF(Beta)). In EPC-hTERT cells, TGF(Beta) alone was not able to induce EMT after 3 days of application. A combined treatment with high LET, however, significantly caused the alteration of EMT markers. To study the function of p53 in the process of EMT, we knocked down P53 through RNA interference. Morphology changes associated with EMT were observed in epithelial cells with silenced p53. Our study indicates: high LET radiation can enhance TGF(Beta) induced EMT; while ATM is triggering the process of TGF(Beta)-induced EMT, p53 might be an essential repressor for EMT phenotypes.

Wang, Minli↗

Tooling Techniques Enhance Medical Imaging

They can release as much energy as tens of billions of hydrogen bombs exploding at the same time. They send protons and electrons rocketing at near the speed of light. They heat gas in the Sun s atmosphere to tens of millions of degrees Celsius. They send a blast of gas and particles toward Earth, posing a danger to spacecraft and astronauts outside the planet s magnetosphere, in rare cases even knocking out radio communications and power grids on the ground. They are so-called solar eruptive events, made up of solar flares and the often associated coronal mass ejections. Because of the scientific mystery of how these solar eruptions are produced on the Sun with such scale and force, and also the major role they play in space weather that can impact life on Earth, NASA researchers have innovated new methods of gathering information about these violent events. One NASA mission, the Reuven Ramaty High Energy Solar Spectroscopic Imager (RHESSI) has significantly advanced understanding of solar flares since its launch in 2002. RHESSI scientists use the spacecraft s imaging spectrometer to piece together pictures of solar flares from the high-energy X-ray and gamma-ray radiation they emit. While there is still much to be learned, data gathered by RHESSI has revealed how magnetic fields in the vast expanse of the solar atmosphere may be the force that drives the immense explosions. The instrument has imaged around 50,000 flares to date, providing information that may explain not only the workings of solar flares but also of much more massive energy releases from distant objects like black holes and quasars. We have been able to make images from X-rays with much finer resolution and greater sensitivity than have ever been made before, says Brian Dennis, RHESSI Mission Scientist and astrophysicist in the Solar Physics Laboratory at Goddard Space Flight Center. The key to RHESSI s unprecedented capabilities lie in a set of essential components a NASA partner created for the mission. The manufacturing techniques developed to create the components have yielded innovations advancing medical imaging, transportation security, and even energy efficiency.

Source record↗

Extraction and Separation Modeling of Orion Test Vehicles with ADAMS Simulation

The Capsule Parachute Assembly System (CPAS) project has increased efforts to demonstrate the performance of fully integrated parachute systems at both higher dynamic pressures and in the presence of wake fields using a Parachute Compartment Drop Test Vehicle (PCDTV) and a Parachute Test Vehicle (PTV), respectively. Modeling the extraction and separation events has proven challenging and an understanding of the physics is required to reduce the risk of separation malfunctions. The need for extraction and separation modeling is critical to a successful CPAS test campaign. Current PTV-alone simulations, such as Decelerator System Simulation (DSS), require accurate initial conditions (ICs) drawn from a separation model. Automatic Dynamic Analysis of Mechanical Systems (ADAMS), a Commercial off the Shelf (COTS) tool, was employed to provide insight into the multi-body six degree of freedom (DOF) interaction between parachute test hardware and external and internal forces. Components of the model include a composite extraction parachute, primary vehicle (PTV or PCDTV), platform cradle, a release mechanism, aircraft ramp, and a programmer parachute with attach points. Independent aerodynamic forces were applied to the mated test vehicle/platform cradle and the separated test vehicle and platform cradle. The aero coefficients were determined from real time lookup tables which were functions of both angle of attack ( ) and sideslip ( ). The atmospheric properties were also determined from a real time lookup table characteristic of the Yuma Proving Grounds (YPG) atmosphere relative to the planned test month. Representative geometries were constructed in ADAMS with measured mass properties generated for each independent vehicle. Derived smart separation parameters were included in ADAMS as sensors with defined pitch and pitch rate criteria used to refine inputs to analogous avionics systems for optimal separation conditions. Key design variables were dispersed in a Monte Carlo analysis to provide the maximum expected range of the state variables at programmer deployment to be used as ICs in DSS. Extensive comparisons were made with Decelerator System Simulation Application (DSSA) to validate the mated portion of the ADAMS extraction trajectory. Results of the comparisons improved the fidelity of ADAMS with a ramp pitch profile update from DSSA. Post-test reconstructions resulted in improvements to extraction parachute drag area knock-down factors, extraction line modeling, and the inclusion of ball-to-socket attachments used as a release mechanism on the PTV. Modeling of two Extraction parachutes was based on United States Air Force (USAF) tow test data and integrated into ADAMS for nominal and Monte Carlo trajectory assessments. Video overlay of ADAMS animations and actual C-12 chase plane test videos supported analysis and observation efforts of extraction and separation events. The COTS ADAMS simulation has been integrated with NASA based simulations to provide complete end to end trajectories with a focus on the extraction, separation, and programmer deployment sequence. The flexibility of modifying ADAMS inputs has proven useful for sensitivity studies and extraction/separation modeling efforts. 1

Fraire, Usbaldo, Jr.↗

Radiative Heating on the After-Body of Martian Entry Vehicles

This paper presents simulations of the radiative heat flux imparted on the after-body of vehicles entering the Martian atmosphere. The radiation is dominated by CO2 bands emitting in the mid-wave infrared spectral region. This mechanism has traditionally not been considered in the design of past Mars entry vehicles. However, with recent analysis showing that the CO2 radiation can be greater than convective heating in the wake, and with several upcoming and proposed missions to Mars potentially affected, an investigation of the impact of this radiation is warranted. The focus of this paper is to provide a better understanding of the impact to aerothermal heating predictions and to provide comparisons between NASA's two main radiation codes, NEQAIR and HARA. The tangent slab approximation is shown to be overly conservative, by as much as 58 percent, for most back- shell body point locations compared to using a full angular integration method. However, due to the complexity of the wake flow, it is also shown that tangent slab does not always represent an upper limit for radiative heating. Furthermore, analysis in this paper shows that it is not possible to provide a general knock-down factor from the tangent slab results to those obtained using the more rigorous full integration method. When the radiative heating is accounted for on the after-body, the unmargined total heat flux can be as high as 14 watts per square centimeter.

After-body↗

Johnson Space Center's Free Range Bicycle Program.- Fall 2015 Intern Report

NASA's Johnson Space Center is a big place, encompassing 1,620 acres and more than a hundred buildings. Furthermore, there are reportedly 15 thousand employees, all of which have somewhere to be. To facilitate the movement of all these people JSC has historically relied on human power. Pedaling their way towards deep space, bicycles have been the go to method. Currently there are about 200 Free Range Bicycles at JSC. Free Range Bicycles belong to nobody, except NASA, and are available for anybody to use. They are not to be locked or hidden (although frequently are) and the intention is that there will always be a bike to hop on to get where you're going (although it may not be the bike you rode in on). Although not without its own shortcomings, the Free Range Bicycle Program has continued to provide low cost, simple transportation for NASA's JSC. In addition to the approximately 200 Free Range Bicycles, various larger divisions (like engineering) will often buy a few dozen bikes for their team members to use or individuals will bring their own personal bike to either commute or use on site. When these bicycles fall into disrepair or are abandoned (from retirees etc) they become a problem at JSC. They are an eye sore, create a safety hazard and make it harder to find a working bike in a time of need. The Free Range Program hopes to address this first problem by "tagging out" abandoned or out of service bicycles. A bright orange "DO NOT OPERATE" tag is placed on the bike and given a serial number for tracking purposes. See picture to the right. If the bike has an active owner with intentions to repair the bike the bottom of the tag has instructions for how to claim the abandoned bicycle. After being tagged the owner of the bicycle has 30 days to claim the bicycle and either haul it off site or get it repaired (and labeled) in accordance with Johnson's Bicycle Policy. If the abandoned bicycle is not claimed within 30 days it becomes the property of the Government. The bicycle is then (in short) repaired, labeled, documented and converted to a free range bicycle. Bikes beyond repair are cannibalized of useable parts and then scrapped. That was nearly the first thing I did when arriving at work. After getting settled in and coordinating the purchase of 50 new bicycles (elaboration below); I started combing the Center. Bikes are hidden and tucked away in the oddest of places and it was my priority to root all of them out. I tagged 70 bikes on the center, setting a record. I tagged so many bikes I ran out tags and had to make more. Long ago it was discovered that the same harsh elements that wreak havoc on the bikes, destroy the tags before the 30 day timeframe. The tags are labeled with instructions on how to claim the bike and numbered, then these paper labels are laminated with packing tape. It sounds like a simple process but nothing fits right, everything has to be trimmed, put on straight and is generally a pain in the neck. So I made an assembly process and knocked out a few hundred to save having to do it again for a while. I walked the center and tagged bikes at every building hiding in nearly every nook and cranny. Thus, in conclusion, I've done many things here at JSC on my first term and had a blast doing it. I've learned a lot from my multi-faceted roles and continual challenges. In short I've done my best to get folks at JSC on bikes and keep folks at JSC on bikes and tended a flock of free range bicycles. Everything from turning the rusty bolts and oiling chains to coordinating a $20,000 deal on 50 new free range bicycles. I am proud of the bicycle shop I have built and am infinitely grateful to the people who lead, help, guide and support me. I have fixed a great number of bicycles and cleaned the center of unsightly and unsafe piles of bicycles. I am immensely thankful for this opportunity to learn and serve and appreciate the privilege of coming back for a second term. A second term, in which I will continue to develop this awesome program.

Lee-Stockton, Willem↗

Additive Manufacturing, Design, Testing, and Fabrication: A Full Engineering Experience at JSC

I worked on several projects this term. While most projects involved additive manufacturing, I was also involved with two design projects, two testing projects, and a fabrication project. The primary mentor for these was Richard Hagen. Secondary mentors were Hai Nguyen, Khadijah Shariff, and fabrication training from James Brown. Overall, my experience at JSC has been successful and what I have learned will continue to help me in my engineering education and profession long after I leave. My 3D printing projects ranged from less than a 1 cubic centimeter to about 1 cubic foot and involved several printers using different printing technologies. It was exciting to become familiar with printing technologies such as industrial grade FDM (Fused Deposition Modeling), the relatively new SLA (Stereolithography), and PolyJet. My primary duty with the FDM printers was to model parts that came in from various sources to print effectively and efficiently. Using methods my mentor taught me and the Stratasys Insight software, I was able to minimize imperfections, hasten build time, improve strength for specific forces (tensile, shear, etc...), and reduce likelihood of a print-failure. Also using FDM, I learned how to repair a part after it was printed. This is done by using a special kind of glue that chemically melts the two faces of plastic parts together to form a fused interface. My first goal with SLA technology was to bring the printer back to operational readiness. In becoming familiar with the Pegasus SLA printer, I researched the leveling, laser settings, and different vats to hold liquid material. With this research, I was successfully able to bring the Pegasus back online and have successfully printed multiple sample parts as well as functional parts. My experience with PolyJet technology has been focused on an understanding of the abilities/limits, costs, and the maintenance for daily use. Still upcoming will be experience with using a composite printer that uses FDM technology to print plastic while laying an internal filament of Kevlar or carbon-fiber inside the printed material. It has been incredible being exposed to this range of technologies and I feel very fortunate to be ready for virtually any kind of printing technology I come across in the future. Design work played a part in my internship this term as well. Working with Hai Nguyen, I was able to design a set of testing tips and a test frame for use with an Arcjet. The testing tips will be made of several different materials that will possibly be used in the heat shield of the Orion space craft. These designs included technical drawings that were presented to the fabrication shop. The frame design was created from 80/20 (a popular brand of frame construction equipment) and included an order form with pricing for fabrication. An independent design was also done for the virtual reality lab. This design was to create a hand-controller based on a previous design. This final design was sent directly to a 3D printer without technical drawings. Overall, my design work has given me experience with using 80/20, helped improve my CAD (Computer Aided Design) proficiency, and increased my knowledge of how to set up technical drawings for fabrication. The final role I have played in this internship has been to assist with testing of the inflatable technology materials working Khadijah Shariff. I began the internship assisting with permeability testing with the initial plan to continue the testing independently after training. Unfortunately, the testing apparatus suffered a technical failure and had funding pulled which cancelled that portion of the project. Further testing with inflatable technology continued with tensile testing of various stitching methods. This testing took place over a two-days and concluded successfully. Final testing was to be more tensile testing but of straps used to connect various inflatable sections. Unfortunately, the needed grips for the tensile tests could not be located and put the testing on hold. It is possible this round of testing will still take place by the end of the internship if the grips can be found. Overall, this portion of the internship has helped me become familiar with one kind of permeability test as well as a popular tensile/compression testing machine. Finally, I also had the chance to be trained using a metal lathe for making very small tips for a soldering iron. These tips will be used to melt threaded brass inserts into 3D printed plastic. Working with James Brown, I was able to successfully machine a brass rod down to as little as 0.064 inches plus or minus 0.001 inches. It was very rewarding to learn how to best use the machine and become familiar with a skill that will undoubtedly be used again in the future. I have been told by several professional engineers that learning to use a lathe and mill will be invaluable skills in the field. This knocks 50 percent of that goal off and I look forward to learning the mill at some point in the future. As is apparent with this list of projects, my internship was not focused on a single over-arching goal. Instead, I was able to gain experience in a myriad of very different areas. I feel like my time here was spent bouncing from one project to the next. Though sometimes difficult to switch gears, it was very rewarding to be a part of so much in so little time. My career and education will be positively impacted by what I have learned at JSC. My experience with 3D printing has improved my ability to handle many issues that may come up in the future with multiple different technologies. The design work I took part in, especially creating technical drawings, will help me better present designs to any engineer or shop I will encounter. My testing experience has helped me become familiar with a popular kind of tensile test machine that will likely be similar to the kinds I will encounter in the future. Finally, my experience with fabrication has given me a rare opportunity, as an engineer, to take part in the fabrication of a part. This experience will help me better tailor my future designs for the manufacturing process and has given me an appreciation for detailed/delicate machining work. My experience at JSC has been successful and will continue to assist me for a long time within the engineering field.

Zusack, Steven↗

After Math - Foamology and Flight Rationale

The Space Shuttle was developed by NASA to be a largely reusable launch system which could provide frequent access to low earth orbit. Like all previous launch systems, safe reentry for the crew and payload required the use of a thermal protection system (TPS). Unlike previous spacecraft though, the Shuttle's TPS was exposed from launch, making it sensitive to debris which could be generated by the vehicle on ascent. The most likely and potentially destructive source of debris was considered to be ice, which could build-up anywhere on the External Tank (ET) where there was exposed metal. Ice could form during ground operations after the cryogenic propellants had been loaded and then be knocked loose on ascent. In order to prevent both ice build-up and boil-off of the propellants, the entire ET and all protuberances (orbiter attach points, pressurization lines, propellant feed lines, etc.) were covered with a spray on foam insulation (SOFI) type TPS. Unfortunately the foam was also susceptible to liberation during ascent, and posed a debris risk of its own. During the early years of the Shuttle Program engineers spent a good deal of effort characterizing the amount of foam that was shed.

Steva, Thomas↗

Impact of Powder Variability on the Microstructure and Mechanical Behavior of Selective Laser Melted Alloy 718

Powder-bed additive manufacturing processes use fine powders to build parts layer-by-layer. Alloy 718 powder feedstocks for selective laser melting (SLM) additive manufacturing are produced commercially by both gas and rotary atomization and are available typically in the 10-45 or 15-45 microns size ranges. A comprehensive investigation was conducted to understand the impact of powder variability on the microstructure and mechanical behavior of SLM 718 heat treated to Aerospace Material Specification (AMS) 5664. This study included sixteen virgin powders and three once-recycled powders within the 10-45 and 15-45 microns size ranges that were obtained from seven direct source suppliers and one reseller. Although alike as highly regular spheroids, these powders showed distinct differences in composition (especially Al, C and N contents), particle size distributions, and powder features such as degree of agglomeration, fusion and surface roughness. Compositional differences expectedly had the strongest impact on microstructure. High N and C contents formed TiN-nitrides and/or (Nb,Ti,Mo)-C carbides on the grain boundaries, prevented recrystallization during heat treatment, and resulted in retained (001)-scalloped shaped grains that ranged from 19 to 41 microns in average size. In the absence of this particle pinning, the average grain size of the heat treated SLM 718 ranged from 51 microns to 90 microns. Room temperature tensile and high cycle fatigue (HCF) testing compared as-fabricated (AF) and low stress ground (LSG) surface conditions. Tensile testing revealed consistent behavior between the two surface conditions and amongst the powder lots. The finer grained SLM 718 builds displayed the lowest tensile properties. A SLM 718 build fabricated from a powder with eight times lower C content showed statistically better tensile properties presumably due to enhanced coarsening of (delta)-Ni3Nb precipitates. The specimens from once-recycled powders had slightly higher tensile strengths and slightly higher ductility compared to their virgin equivalents; once-recycling also did not substantially degrade the mean HCF life. The LSG fatigue lives agreed with conventionally manufactured 718 data, while AF lives exhibited a knock-down due to surface roughness. The fatigue lives of AF specimens were statistically equivalent across powder lots except for one and failures typically initiated at stress concentrators associated with SLM surface asperities. Fatigue testing of low stress ground specimens result in both transgranular and within facet crack initiations. More than half of the cracks initiated from these facets for the machined condition; however, these facets appeared to be within grains that were larger-than-average in size. A nitrogen-atomized powder with fine prior particles of TiN-nitrides and M(Ti,Nb,Mo)C carbides from atomization on powder surfaces resulted in the best fatigue performance with segregation of these particles to the SLM 718 grain boundaries leading to higher resistance to early-stage crack propagation. Typically the fine-grained builds with minor phases along the grain boundaries did not perform well in fatigue, whereas a larger-grain build with lower carbon content and coarser delta-Ni3Nb precipitates showed the next best HCF response. Further details of the build microstructure and its impact on tensile and fatigue behavior was considered.

laser deposition↗

On the Development of Shell Buckling Knockdown Factors for Stiffened Metallic Launch Vehicle Cylinders

From the 1920s to the early 1970s, many shell buckling experiments were conducted in an effort to understand the complex buckling behavior exhibited by thin-walled cylindrical shells, to provide data to correlate with new shell stability theories, and provide design guidelines. Typically, the experiments yielded buckling loads that were substantially lower than the corresponding analytical predictions, which were based on simplified linear bifurcation analyses of geometrically perfect shells with nominal dimensions and idealized boundary conditions. The seminal works by von Kármán and Tsien, by Donnell and Wan, and by Koiter identified small deviations from the idealized geometry of a shell, known as initial geometric imperfections, as a primary source of the discrepancy between corresponding analytical predictions and experimental results. However, the computational tools and capabilities at that time could not perform the nonlinear analyses needed to assess the effects of these imperfections on the buckling behavior of thin-walled shells. Thus, buckling design allowables were determined by establishing lower bounds to test data. Specifically, empirical design factors, that have become known as knockdown factors, were determined and were to be used in conjunction with linear bifurcation analyses for simply supported shells; that is, these empirical factors were used to "knock down" the value of the unconservative simplified analytical prediction. This approach to shell buckling design has proved satisfactory for most design purposes and remains prominent in industry practice, as evidenced by the extensive use of the NASA space vehicle design criteria and recommendations. Unfortunately, the current design guidelines have not been updated since they were first published in the late 1960s and may not be able to take full advantage of modern materials, precision manufacturing processes, and new structural concepts.

Hilburger, Mark W.↗

The Effects of CDKN1a/p21 on Oxidative Stress and Mitochondrial Function During Long Duration Spaceflight

Spaceflight factors, such as microgravity and space radiation, are known to put astronauts at risk for negative effects to their tissue regeneration and degenerative conditions. On our previous spaceflight research, we found that long duration spaceflight produced increased oxidative stress and activation of the inflammatory response as a major contributor to physiological changes, including alterations to the cardiovascular and musculoskeletal systems, metabolism, and the liver. Proliferation, apoptosis, and ion-channel remodeling of vascular smooth muscle cells, as well as endothelial inflammation, and nitric oxide synthase-nitric oxide system regulation have been shown by spaceflight and simulated spaceflight projects. CDKN1ap21 is a regulatory gene for tissue regeneration and also plays an important role in upregulating oxidative stress caused by radiation. In further research, we have also determined CDKN1ap21 to be overexpressed during spaceflight. When knocked out in mice, however, it protects against unloading-induced changes to the morphology and physiology of carotid arteries. In this proposal, we seek to test a potential dietary countermeasure to down-regulate CDKN1ap21 in the mice and protect against oxidative stress in the rodents. Specifically, we will expose both Wildtype and CDKN1ap21-null mice to hydrogen peroxide to induce oxidative stress and observe the molecular mechanisms in which a dietary supplement protects vascular smooth muscle cells against the consequences of the apoptotic environment within Wildtype mice versus the, hypothetically, sound physiology of CDKN1ap21-null mice. The successful completion of this experiment will conclusively determine accuracy of a dietary supplement as a CDKN1ap21 suppressor. This will provide a new perspective on the problem of increased oxidative stress developing into cardiovascular disease as a result of long-term space flight. This research will address the Human Research Plan Roadmaps Risk of Cardiac Rhythm Problems including CV-8, the Risk of Cardiovascular Disease and Other Degenerative Tissue Effects from Radiation Exposure including Degen-6 and Degen-7, and the Risk of Adverse Health Event from Radiation Exposure including IM-8. Additionally, this research will address Space Biology Research Plans questions SBP CMB-1, SBP CMB-3, and SB AN-2.

Oxidative Stress↗

Environmental Testing Of High Temperature Materials and Coatings

Materials for today′s extreme environments have unique challenges and design requirements that require multi-faceted evaluations. Thermal and mechanical testing and analysis is important in design, but environmental effects are often the limiting factor of materials in service. Degradation modes such as oxidation, recession, erosion, foreign object damage, and chemical corrosion can negatively impact the materials thermo-mechanical behavior. While materials may ultimately fail under thermo−mechanical stresses, environmental effects are many times the root cause. Evaluation of materials systems under relevant conditions are critical.....start by identifying mechanisms and develop corresponding test methods. Comprehensive modeling begins with thermo-mechanical behavior, then considers environmental degradation modes that provide a “knock down” of that behavior.

Thermal testing Mechanical testing↗

Earth anisotropic reflection and the orbit of LAGEOS

Radiation pressure due to sunlight anisotropically reflected from the oceans apparently cannot explain the fluctuations in the anomalous along-track deceleration of the LAGEOS satellite. It fails by about a factor of 2 to account for the major peaks in the acceleration. This result is based on an extreme model: a cloudless earth whose northern hemisphere consists of continent, and whose southern hemisphere consists of ocean. The continent is assumed to reflect sunlight according to Lambert's law, while the ocean reflects anisotropically according to a simple analytical law which mimics Nimbus 7 observations. The inclusion of clouds into the model would reduce the acceleration to perhaps an order of magnitude below those observed. Some other explanation for the fluctuations, which have magnitude about 2 x 10 to the -12th m/sec sq, must be sought.

Rubincam, David Parry↗