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At least 199 records · Page 11

Visualization of clustered protocadherin neuronal self-recognition complexes

Neurite self-recognition and avoidance are fundamental properties of all nervous systems. These processes facilitate dendritic arborization, prevent formation of autapses and allow free interaction among non-self neurons. Avoidance among self neurites is mediated by stochastic cell-surface expression of combinations of about 60 isoforms of α-, β- and γ-clustered protocadherin that provide mammalian neurons with single-cell identities. Avoidance is observed between neurons that express identical protocadherin repertoires, and single-isoform differences are sufficient to prevent self-recognition. Protocadherins form isoform-promiscuous cis dimers and isoform-specific homophilic trans dimers. Although these interactions have previously been characterized in isolation, structures of full-length protocadherin ectodomains have not been determined, and how these two interfaces engage in self-recognition between neuronal surfaces remains unknown. Here we determine the molecular arrangement of full-length clustered protocadherin ectodomains in single-isoform self-recognition complexes, using X-ray crystallography and cryo-electron tomography. We determine the crystal structure of the clustered protocadherin γB4 ectodomain, which reveals a zipper-like lattice that is formed by alternating cis and trans interactions. Using cryo-electron tomography, we show that clustered protocadherin γB6 ectodomains tethered to liposomes spontaneously assemble into linear arrays at membrane contact sites, in a configuration that is consistent with the assembly observed in the crystal structure. These linear assemblies pack against each other as parallel arrays to form larger two-dimensional structures between membranes. Furthermore, our results suggest that the formation of ordered linear assemblies by clustered protocadherins represents the initial self-recognition step in neuronal avoidance, and thus provide support for the isoform-mismatch chain-termination model of protocadherin-mediated self-recognition, which depends on these linear chains.

59 BASIC BIOLOGICAL SCIENCES↗

Improved LMS algorithm for adaptive beamforming

Two adaptive algorithms which make use of all the available samples to estimate the required gradient are proposed and studied. The first algorithm is referred to as the recursive LMS (least mean squares) and is applicable to a general array. The second algorithm is referred to as the improved LMS algorithm and exploits the Toeplitz structure of the ACM (array correlation matrix); it can be used only for an equispaced linear array.

Godara, Lal C.↗

Phase-Only Beam Broadening of Contiguous Uniform Subarrayed Arrays

In modern antenna systems, beam broadening of subarrayed arrays provides continuous coverage of a wide angular extent in a cost-effective manner. While many methods have been published that address beam broadening of traditional (non-subarrayed) arrays, there is a knowledge gap in the published literature with respect to efficient beam broadening of contiguous uniform subarrayed arrays. This article presents efficient methods for beam broadening of contiguous uniform subarrayed arrays where the excitation of each element is not individually controlled, but the elements of the array are grouped together as subarrays to have the same element excitations. Particularly, this article focuses on phase-only optimization to preserve maximum power output. Additionally, three modilied iterative Fourier transform (IFT) methods and one genetic algorithm (GA) are presented to efliciently search the vast solution space of possible phase settings for a solution that satislies the desired broadened pattern. These methods are evaluated on idealized 1 x 40 and 1 x 80 linear arrays with live element subarrays and 40 x 40 and 80 x 80 element rectangular arrays with 5 x 5 element subarrays. The proposed modilied IFT methods are found to be faster than the GA approach, while the GA approach only offers a few percentage points of better effectiveness.

42 ENGINEERING↗

Multi-particle trapping and manipulation by a high-frequency array transducer

We report the multiple micro-particle trapping and manipulation by a single-beam acoustic tweezer using a high-frequency array transducer. A single acoustic beam generated by a 30 MHz ultrasonic linear array transducer can entrap and transport multiple micro-particles located at the main lobe and the grating lobes. The distance between trapped particles can be adjusted by changing the transmit arrangement of array-based acoustic tweezers and subsequently the location of grating lobes. The experiment results showed that the proposed method can trap and manipulate multiple particles within a range of hundreds of micrometers. Due to its simplicity and low acoustic power, which is critical to protect cells from any thermal and mechanical damages, the technique may be used for transportation of cells in cell biology, biosensors, and tissue engineering.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Photovoltaic, gravitationally-stabilized solid-state, satellite solar power station /GSS4PS/

The salient feature of a gravitationally-stabilized satellite solar power system (SSPS) for a photovoltaic system is that the large solar array is separated into smaller segments or subunits, joined together in a linear array oriented along the local vertical. Applicability of gravitational stabilization to the design of photovoltaic SSPS is demonstrated. Both actively controlled systems using multiple solar panels oriented to the sun and passively controlled systems requiring no sun orientation are considered and determined to be feasible. Expressions for gravity-gradient induced tension and restoring torques about the local vertical are assessed. Particular attention is directed to the applicability of solid-state approaches to the design of SSPS. It is shown that an all solid-state SSPS utilizing the LITOMIC (light-to-microwave conversion) concept is feasible but that a hybrid system employing a combination of both solid-state and cryogenic cooled low-voltage techniques to the design of the power management and distribution subsystem may also provide a solution.

Cantafio, L. J.↗

Visible and shortwave infrared focal planes for remote sensing instruments

The development of solid-state sensor technology for multispectral linear array (MLA) instruments is described. A buttable four-spectral-band linear-format CCD and a buttable two-spectral band linear-format short-wave IR CCD have been designed, and first samples have been demonstrated. In addition, first-sample four-band interference filters have been fabricated, and hybrid packaging technology is being developed. Based on this development work, the design and construction of focal planes for a Shuttle sortie MLA instrument have begun. This work involves a visible and near-IR focal plane with 2048 pixels x 4 spectral bands and a short-wave IR focal plane with 1024 pixels x 2 spectral bands.

Tower, J. R.↗

Valles Marineris, Mars: Are pit chains formed by erosion and troughs by tectonism?

The origin of the Valles Marineris remains controversial. Erosional, tectonic, and hybrid processes have been proposed. To clarify these contradictions, the widths and depths of pit chains and troughs were compared and it was found that the features do not form a continuum. Rather, results are consistent with the hypothesis that pit chains formed by surficial collapse and troughs by deeper seated and coherent failure. All pit chains and linear depressions in the Valles Marineris region were classified by inspection into six morphologic categories: pit chains (linear arrays of small pits); floored chains (arrays of pit chains having flat or hummocky floors); scalloped troughs (wider linear depressions with scalloped wall segments); narrow troughs (depressions of intermediate width with straight wall segments); wide troughs (broad, linear depressions); and chaotic troughs (more irregular depressions displaying some channel morphologies). Topographic profiles were drawn across the classified depressions and the erosional width was determined between plateau margins along with the depth from the surrounding plateau level to the deepest part.

Lucchitta, Baerbel K.↗

Arrays of Bolometers for Far-infrared and Submillimeter Astronomy

We describe 12 x 32 arrays of semiconducting cryogenic bolometers designed for use in far-infrared and submillimeter cameras. These 12 x 32 arrays are constructed from 1 x 32 monolithic pop-up detectors developed at NASA Goddard Space Flight Center. The pop-up technology allows the construction of large arrays with high filling factors that provide efficient use of space in the focal planes of far-infrared and submillimeter astronomical instruments. This directly leads to a significant decrease in observing time. The prototype array is currently operating in SHARC II, a facility instrument in use at the Caltech Submillimeter Observatory (CSO). The elements of this array employ a bismuth absorber coating and quarter wave backshort to optimize the bolometer absorption for a passband centered at 350 microns. However, this resonant structure also provides good bolometer performance at 450 and 850 microns, the two additional SHARC II passbands. A second array is to be installed in the High-resolution Airborne Widebandwidth Camera (HAWC), a far-infrared imaging camera for the Stratospheric Observatory for Infrared Astronomy (SOFIA). This array is currently in the final stage of construction, and its completion is expected in early 2004. HAWC is scheduled for commissioning in 2005. The HAWC array employs titanium-gold absorbers and is optimized for uniform absorption from 40 to 300 microns to accommodate all four of its far-infrared passbands. We describe the details of the array construction including the mechanical design and electrical characterization of the constituent linear arrays, comparing the SHARC II and HAWC cases. We also summarize the overall characteristics of the final two-dimensional arrays. Finally, we show examples of array performance in the form of images obtained with SHARC II.

Chuss, D. T.↗

Airborne spectrograph for the thermal IR: Broadband Array Spectrograph System

Spectroscopic studies in the 'fingerprint' region of the thermal IR from 3 to 14 microns of celestial dust components and the overall energy distribution of the sources are best served by moderate spectral resolution (R = lambda/Delta lambda approximately 30 to 200), high sensitivity observations. Spectral purity and the reproducibility of the spectral shape are critical as well, when using the spectral shape to assign temperatures to dust grains or to gas clouds based on the wavelength and shape of molecular bands. These sensor attributes are also important to the use of wavelengths and ratios of solid state features to derive compositions of dust grains in celestial sources. The advent of high quality linear arrays of blocked impurity band (BIB) detectors of Si:As permitted the development of a state-of-the-art, patented, cooled prism spectrograph. Developed at The Aerospace Corporation largely with in-house funds, the Broadband Array Spectrograph System (BASS) has been used for a variety of remote sensing applications, but especially for IR astronomical studies on the Kuiper Airborne Observatory and at the NASA Infrared Telescope Facility (IRTF). The attributes of the spectrograph, specifically having the pupil imaged onto the 2 linear 58 element detector arrays so that the effects of guiding errors are minimized, being able to maximally exploit the limited observing time by acquiring all 116 spectral channels simultaneously, and having all spectral channels imaged through the same aperture so that spectral mapping is readily and reliably accomplished, afford the scientist with a unique opportunity to conduct both surveys of examples of many different types of sources as well as in-depth studies of a given class of object by thoroughly sampling the class members. This duality was demonstrated with the BASS through a combination of KAO flights where spectral maps were obtained as part of in-depth studies of specific source regions (such as Orion and W3) and flights where up to 21 legs/flight were used to survey many different sources of different types.

Russell, Ray W.↗

An Agile Beam Transmit Array Using Coupled Oscillator Phase Control

A few years ago York and colleagues suggested that injection locking of voltage controlled oscillators could be used to implement beam steering in a phased array [I]. The scheme makes use of the fact that when an oscillator is injection locked to an external signal, the phase difference between the output of the oscillator and the injection signal is governed by the difference between the injection frequency and the free running frequency of the oscillator (the frequency to which the oscillator is tuned). Thus, if voltage controlled oscillators (VCOs) are used, this phase difference is controlled by an applied voltage. Now, if a set of such oscillators are coupled to nearest neighbors, they can be made to mutually injection lock and oscillate as an ensemble. If they are all tuned to the same frequency, they will all oscillate in phase. Thus, if the outputs are connected to radiating elements forming a linear array, the antenna will radiate normal to the line of elements. Scanning is accomplished by antisymmetrically detuning the end oscillators in the array by application of a pair of appropriate voltages to their tuning ports. This results in a linear phase progression across the array which is just the phasing required to scan the beam. The scan angle is determined by the degree of detuning. We have constructed a seven element one dimensional agile beam array at S-band based on the above principle. Although, a few such arrays have been built in the past, this array possesses two unique features. First, the VCO MMICs have buffer amplifiers which isolate the output from the tuning circuit, and second, the oscillators are weakly coupled to each other at their resonant circuits rather than their outputs. This results in a convenient isolation between the oscillator array design and the radiating aperture design. An important parameter in the design is the so called coupling phase which determines the phase shift of the signals passing from one oscillator to its neighbors. Using this array, we have been able to verify the theoretical predictions concerning the effect of this phase on both the locking range and ensemble frequency of the array. However, the scan range achieved fell somewhat short of the theoretical value because of the amplitude variation of the oscillator outputs with tuning.

Pogorzelski, Ronald S.↗

Comparisons between wave directional spectra from SAR and pressure sensor arrays

Simultaneous directional wave measurements were made at Torrey Pines Beach, California, by a synthetic aperture radar (SAR) and a linear array of pressure sensors. The measurements were conducted during the West Coast Experiment in March 1977. Quantitative comparisons of the normalized directional spectra from the two systems were made for wave periods of 6.9-17.0 s. The comparison results were variable but generally showed good agreement of the primary mode of the normalized directional energy. An attempt was made to quantify the physical criteria for good wave imaging in the SAR. A frequency band analysis of wave parameters such as band energy, slope, and orbital velocity did not show good correlation with the directional comparisons. It is noted that absolute values of the wave height spectrum cannot be derived from the SAR images yet and, consequently, no comparisons of absolute energy levels with corresponding array measurements were intended.

Pawka, S. S.↗

A renormalization group model for the stick-slip behavior of faults

A fault which is treated as an array of asperities with a prescribed statistical distribution of strengths is described. For a linear array the stress is transferred to a single adjacent asperity and for a two dimensional array to three ajacent asperities. It is shown that the solutions bifurcate at a critical applied stress. At stresses less than the critical stress virtually no asperities fail on a large scale and the fault is locked. At the critical stress the solution bifurcates and asperity failure cascades away from the nucleus of failure. It is found that the stick slip behavior of most faults can be attributed to the distribution of asperities on the fault. The observation of stick slip behavior on faults rather than stable sliding, why the observed level of seismicity on a locked fault is very small, and why the stress on a fault is less than that predicted by a standard value of the coefficient of friction are outlined.

Smalley, R. F., Jr.↗

A renormalization group approach to the stick-slip behavior of faults

A fault which is treated as an array of asperities with a perscribed statistical distribution of strengths is described. For a linear array the stress is transferred to a single adjacent asperity and for a two dimensional array to three adjacent asperities. It is shown that the solutions bifurcate at a critical applied stress. At stresses less than the critical stress virtually no asperities fail on a large scale and the fault is locked. At the critical stress the solution bifurcates and asperity failure cascades away from the nucleus of failure. It is found that the stick slip behavior of most faults can be attributed to the distribution of asperities on the fault. The observation of stick slip behavior on faults rather than stable sliding, why the observed level of seismicity on a locked fault is very small, and why the stress on a fault is less than that predicted by a standard value of the coefficient of friction are outlined.

Smalley, R. F., Jr.↗

Shuttle imaging spectrometer optics

This paper discusses the optical design and performance of the Shuttle Imaging Spectrometer (SISEX) optical system, which is being planned for the next generation of Earth remote sensing instruments. This optical system represents a new approach to remote sensing in which wide-field optics, dispersing elements, and area detector arrays are used in place of mechanical scanners, filters, and discrete detector elements or linear arrays. While the SISEX optical system is designed specifically for flight on Shuttle, the same optical approach is being used in the design of other remote sensing instruments, such as the High Resolution Imaging Spectrometer, which is expected to fly on the Earth Observing System.

Page, N. A.↗

Integrating 128 element InSb array - Recent results

There has been a continuing evolution toward larger arrays of infrared detectors, and the technology base derived from the Galileo Near Infrared Mapping Spectrometer (NIMS) has been expanded to linear arrays including from 128 to 512 elements. This advance is based on the commercial availability of high-quality InSb photodiodes and 128/256 element FET switch MUX's (multiplexing elements). The present investigation is concerned with an experimental 128-element linear imager using InSb detectors and silicon MUX for readout. Attention is given to detector array electrical characteristics, the detector readout architecture, noise, and special effects.

Bailey, G.↗

Cartographic potential of a spacecraft line-array camera system - Stereosat

A study of the Stereosat mission, which may acquire analog/digital stereo image data of cartographic quality with linear array camera systems, is presented, with attention given to the Stereosat system and the mission parameters, the utilization of the Stereosat studies in order to indicate the nature and scope of the problems associated with recording image data of high geometric fidelity from spacecraft equipped with line array sensors, and the assessing of the possibilities of meeting the completeness and accuracy requirements of cartographic products. A 713-km circular, sun-synchronous, near polar orbit, with an inclination of 98.24 deg and a repeat cycle of 48 days is designed to insure global coverage of the earth's land masses during the three-year lifetime of the mission. Three cameras (fore, vertical, and aft looking), mounted so as to record stereotriplets for a 61.4 km wide swath at a nominal focal plane scale of 1:1,000,000, are considered. The IFOV of 15 m should be adequate for producing thematic and image maps at scales of 1:50,000 to 1:250,000. The value of the coverage to cartographers will be dictated by the accuracy of the digital image data, which is largely a function of satellite control.

Welch, R.↗

Diffraction-Based Optical Switching with MEMS

In this article, we are presenting an overview of MEMS-based (Micro-Electro-Mechanical System) optical switch technology starting from the reflective two-dimensional (2D) and three-dimensional (3D) MEMS implementations. To further increase the speed of the MEMS from these devices, the mirror size needs to be reduced. Small mirror size prevents efficient reflection but favors a diffraction-based approach. Two implementations have been demonstrated, one using the Texas Instruments DLP (Digital Light Processing), and the other an LCoS-based (Liquid Crystal on Silicon) SLM (Spatial Light Modulator). These switches demonstrated the benefit of diffraction, by independently achieving high speed, efficiency, and high number of ports. We also demonstrated for the first time that PSK (Phase Shift Keying) modulation format can be used with diffraction-based devices. To be truly effective in diffraction mode, the MEMS pixels should modulate the phase of the incident light. We are presenting our past and current efforts to manufacture a new type of MEMS where the pixels are moving in the vertical direction. The original structure is a 32 x 32 phase modulator array with high contrast grating pixels, and we are introducing a new sub-wavelength linear array capable of a 310 kHz modulation rate

36 MATERIALS SCIENCE↗

Integrating IR detector imaging systems

An integrating IR detector array for imaging is provided in a hybrid circuit with InSb mesa diodes in a linear array, a single J-FET preamplifier for readout, and a silicon integrated circuit multiplexer. Thin film conductors in a fan out pattern deposited on an Al2O3 substrate connect the diodes to the multiplexer, and thick film conductors also connect the reset switch and preamplifier to the multiplexer. Two phase clock pulses are applied with a logic return signal to the multiplexer through triax comprised of three thin film conductors deposited between layers. A lens focuses a scanned image onto the diode array for horizontal read out while a scanning mirror provides vertical scan.

Bailey, G. C.↗