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At least 199 records · Page 11

Printed Strain Gauges for High Temperature Applications (>300°C)

The real-time understanding of strain and deformation of materials provides prognostic health monitoring of components of current operational reactors and valuable data that shortens the timeline for the development of new nuclear-relevant materials in test reactor experiments. This report discusses the current development and testing of additively manufactured strain gauges. This has potential to improve the sensor design and manufacturing techniques to meet the requirements of the current and advanced nuclear reactors (i.e., in terms of environment conditions, sample geometry, and materials compatibility). The developmental additively manufactured strain gauges are exposed to separate effects testing (i.e., mechanical strain, high temperature) to determine environmental factors that affect the strain gauge. In addition, sensor qualification methodologies are further developed for determining the reliability and robustness at the interface of the AM strain gauge materials.

36 MATERIALS SCIENCE↗

Electronic structure of α - RuCl 3 by fixed-node and fixed-phase diffusion Monte Carlo methods

Layered material α-RuCl 3 has caught wide attention due to its possible realization of Kitaev's spin liquid and its electronic structure that involves the interplay of electron-electron correlations and spin-orbit effects. Several DFT+U studies have suggested that both electron-electron correlations and spin-orbit effects are crucial for accurately describing the band gap. This work studies the importance of these two effects using fixed-node and fixed-phase diffusion Monte Carlo calculations both in spin-averaged and explicit spin-orbit formalisms. In the latter, the Slater-Jastrow trial function is constructed from two-component spin orbitals using our recent quantum Monte Carlo (QMC) developments and thoroughly tested effective core potentials. Our results show that the gap in the ideal crystal is already accurately described by the spin-averaged case, with the dominant role being played by the magnetic ground state with significant exchange and electron correlation effects. We find qualitative agreement between hybrid DFT, DFT+U, and QMC. In addition, QMC results agree very well with available experiments, and we identify the values of exact Fock exchange mixing that provide comparable gaps. Explicit spin-orbit QMC calculations reveal that the effect of spin-orbit coupling on the gap is minor, of the order of 0.2 eV, which corresponds to the strength of the spin orbit of the Ru atom.

36 MATERIALS SCIENCE↗

Precision grid and hand motion for accurate needle insertion in brachytherapy

Purpose: In prostate brachytherapy, a grid is used to guide a needle tip toward a preplanned location within the tissue. During insertion, the needle deflects en route resulting in target misplacement. In this paper, 18-gauge needle insertion experiments into phantom were performed to test effects of three parameters, which include the clearance between the grid hole and needle, the thickness of the grid, and the needle insertion speed. Measurement apparatus that consisted of two datum surfaces and digital depth gauge was developed to quantify needle deflections. Methods: The gauge repeatability and reproducibility (GR and R) test was performed on the measurement apparatus, and it proved to be capable of measuring a 2 mm tolerance from the target. Replicated experiments were performed on a 2{sup 3} factorial design (three parameters at two levels) and analysis included averages and standard deviation along with an analysis of variance (ANOVA) to find significant single and two-way interaction factors. Results: Results showed that grid with tight clearance hole and slow needle speed increased precision and accuracy of needle insertion. The tight grid was vital to enhance precision and accuracy of needle insertion for both slow and fast insertion speed; additionally, at slow speed the tight, thick grid improved needle precision and accuracy. Conclusions: In summary, the tight grid is important, regardless of speed. The grid design, which shows the capability to reduce the needle deflection in brachytherapy procedures, can potentially be implemented in the brachytherapy procedure.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

SPACE code simulation of cold leg small break LOCA in the ATLAS integral test

SPACE code is a system analysis code for pressurized water reactors. This code uses a two-fluid and three-field model. For a few years, intensive validations have been performed to secure the prediction accuracy of models and correlations for two-phase flow and heat transfer. Recently, the code version 1.0 was released. This study is to see how well SPACE code predicts thermal hydraulic phenomena of an integral effect test. The target experiment is a cold leg small break LOCA in the ATLAS facility, which has the same two-loop features as APR1400. Predicted parameters were compared with experimental observations. (authors)

22 GENERAL STUDIES OF NUCLEAR REACTORS↗

Recent progress on the superconducting ion source VENUS

The 28 GHz Ion Source VENUS (versatile ECR for nuclear science) is back in operation after the superconducting sextupole leads were repaired and a fourth cryocooler was added. VENUS serves as an R and D device to explore the limits of electron cyclotron resonance source performance at 28 GHz with its 10 kW gryotron and optimum magnetic fields and as an ion source to increase the capabilities of the 88-Inch Cyclotron both for nuclear physics research and applications. The development and testing of ovens and sputtering techniques cover a wide range of applications. Recent experiments on bismuth demonstrated stable operation at 300 e{mu}A of Bi{sup 31+}, which is in the intensity range of interest for high performance heavy-ion drivers such as FRIB (Facility for Rare Isotope Beams). In addition, the space radiation effects testing program at the cyclotron relies on the production of a cocktail beam with many species produced simultaneously in the ion source and this can be done with a combination of gases, sputter probes, and an oven. These capabilities are being developed with VENUS by adding a low temperature oven, sputter probes, as well as studying the RF coupling into the source.

43 PARTICLE ACCELERATORS↗

Tests of modified gravity with dwarf galaxies

In modified gravity theories that seek to explain cosmic acceleration, dwarf galaxies in low density environments can be subject to enhanced forces. The class of scalar-tensor theories, which includes f(R) gravity, predict such a force enhancement (massive galaxies like the Milky Way can evade it through a screening mechanism that protects the interior of the galaxy from this ''fifth'' force). We study observable deviations from GR in the disks of late-type dwarf galaxies moving under gravity. The fifth-force acts on the dark matter and HI gas disk, but not on the stellar disk owing to the self-screening of main sequence stars. We find four distinct observable effects in such disk galaxies: 1. A displacement of the stellar disk from the HI disk. 2. Warping of the stellar disk along the direction of the external force. 3. Enhancement of the rotation curve measured from the HI gas compared to that of the stellar disk. 4. Asymmetry in the rotation curve of the stellar disk. We estimate that the spatial effects can be up to 1 kpc and the rotation velocity effects about 10 km/s in infalling dwarf galaxies. Such deviations are measurable: we expect that with a careful analysis of a sample of nearby dwarf galaxies one can improve astrophysical constraints on gravity theories by over three orders of magnitude, and even solar system constraints by one order of magnitude. Thus effective tests of gravity along the lines suggested by Hui, Nicolis, and Stubbs (2009) and Jain (2011) can be carried out with low-redshift galaxies, though care must be exercised in understanding possible complications from astrophysical effects.

79 ASTRONOMY AND ASTROPHYSICS↗

Mechanical Testing of Hydrided Fuel Cladding

The U.S. Department of Energy Office of Nuclear Energy, Office of Fuel Cycle Technology established the Used Fuel Disposition Campaign (UFDC) to conduct research and development activities related to storage, transportation, and disposal of used nuclear fuel (UNF) and high-level radioactive waste. Within the UFDC, the storage and transportation task has been created to address issues of extended storage and transportation. One gap in knowledge identified as high priority by UFDC includes hydrogen effects in zirconium alloy cladding and reorientation of cladding hydrides. During reactor operations, hydrogen is generated from the oxidation of the surface of zirconium alloy materials in the coolant of light water reactors can be absorbed into the cladding and form zirconium hydrides. At high temperatures and hoop stresses, these normally circumferential oriented hydrides in high burnup UNF (HB-UNF) may reorient in the radial direction and affect the mechanical properties of the cladding. Understanding these changes in mechanical properties will aid in analyzing how UNF will perform during storage and transportation. Separate effects testing to measure the mechanical properties of un-hydrided, pre-hydrided, and irradiated HB-UNF is currently underway at Pacific Northwest National Laboratory (PNNL). In order to measure these mechanical properties, staff at PNNL are employing tensile, compression, and burst testing. Systems have been developed to pre-hydride cladding and reorient cladding hydrides. The development of these systems and the testing methods are described herein.

Cladding, Zirconium, Hydrides, Mechanical Testing↗

Predictive Models and Novel Accelerated Tests for the Reliability of Cell Metallization and Solder Joints in Photovoltaic Modules

Interconnect, solder, and metallization-related failures are the primary reason for premature Si-based photovoltaic panel failure [1, 2] and can lead to a cascade of other failures, including thermal events. This combination of high severity and high occurrence means that understanding interconnect-related failures is key to the long-term health of the photovoltaic industry, and it is crucial that the industry adopt efficient and effective tests that aid in design-for-reliability and manufacturing quality control.

14 SOLAR ENERGY↗

Understanding and modeling current and future coastal wetland methane dynamics (Final Report)

The coastal terrestrial-aquatic interface (TAI) is a highly dynamic component of the Earth system that plays a critical role in biogeochemical cycling. Due to its dynamic nature, the processes that regulate decomposition and methane (CH 4 ) emissions are of greater significance at the TAI than in upland systems. Despite this, we have limited mechanistic understanding of how climate stressors interact to regulate the electron acceptors and donors that determine decomposition pathways within TAIs, including the generation of hot spots and hot moments. Accurately modeling these processes is critical for incorporating the coastal TAI into Earth systems models, such as DOE’s E3SM. With previous DOE support, we adapted an aerobic terrestrial representation of decomposition using PFLOTRAN, a reactive flow and transport model, and added anerobic decomposition pathways, salinity, and oxygen (O 2 ) that fluctuates independently of water table level. However, because this model (PFLOTRAN TAI ) is based on decomposition rates and organic matter carbon to nitrogen ratios from terrestrial systems, its performance in TAI systems is currently limited by the lack of empirical data to properly parameterize variables. In addition, while PFLOTRAN TAI can simulate movement of O 2 into sediments, it is not currently capable of tracking the movement of CH 4 gas through plant tissues due to both current model structure and lack of available data. Our overall objective of the project was the increase our mechanistic understanding of CH 4 dynamics in response to environmental change, such that we can improve the representation of these dynamics in PFLOTRAN. We installed automated flux chambers in a new field-scale active soil warming experiment and set up marsh organs (mesocosms) to test effects of warming, flooding, and salinity. This resulted in a new dataset consisting of chamber-level CH 4 flux measurements across multiple sites, ecological conditions, and timeframes, as well as corresponding measurements on porewater chemistry, soil carbon quality, plant biomass, and redox reaction rates. Using these data, we improved PFLOTRAN TAI to more accurately model CH 4 dynamics and successfully tested our hypotheses. This grant contributed to the professional development of 3 postdocs, 4 undergraduate interns, 4 teacher interns, 17 technicians, and 15 participatory scientists. The automated chamber technology designed for this grant has also been shared with multiple new projects.

54 ENVIRONMENTAL SCIENCES↗

Plane-Strain Tension Testing of ATF FeCrAl Cladding (Progress Report)

Performance of advanced accident-tolerant fuel (ATF) claddings must be assessed under all relevant scenarios, including normal and off-normal operating conditions, as well as during a reactivity-initiated accident (RIA). During RIA, the fuel pellet may expand and cause significant loads on cladding, a condition known as pellet cladding mechanical interaction (PCMI), which may even lead to cladding failure. This report describes the fiscal year (FY) 2020 research activities and results from the development of separate-effects testing for ATF cladding candidate iron-chromium-aluminum (FeCrAl) tube specimens under loading conditions expected during RIA/PCMI events. To assess material performance under PCMI, a high strain rate burst test, often termed the modified burst test (MBT), is commonly employed. However, execution of such a test in a hot cell requires significant research. To overcome the complexities of performing MBTs in a hot-cell environment on irradiated samples, a plane-strain tension (PST) test was proposed by several authors as an alternative approach for PCMI testing. A new fixture was developed so that PST specimens could be tested using a more accommodating design for hot-cell manipulators. This report presents the PST fixture design, evaluates the possibility of modifying the specimen geometry, and discusses experimental results with unirradiated Al 6061 and FeCrAl tubes at various lengths. Furthermore, this report discusses the relevance and compatibility of the PST results to RIA scenarios and compares the PST and MBT results.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Status Report on Development of MARCH Module Designs

The Transient Reactor Test (TREAT) facility was constructed in the late 1950’s, provided thousands of transient irradiations before being placed in standby in 1994, and was restarted in 2017 in order to resume its crucial role in nuclear heated safety research. Advances in modern computational capabilities and a resurgence of interest in novel reactor technology have created an opportunity for emphasizing modern science-based and separate effects test capabilities at TREAT. An innovative approach to this type of testing leverages the relatively low radioisotope accumulation during brief TREAT irradiations by arranging small fresh fuel specimens in low activation hardware “modules” so that they can be easily extracted and shipped for examination within weeks. The concept was termed the Minimal Activation Retrievable Capsule Holder (MARCH) irradiation vehicle system, and its maturation began under a Lab Directed Research and Development (LDRD) project starting in fiscal year 2017. Within the first year of this project, enough design and predictive modeling had been performed to prove the principle and ascertain support from major direct-funded DOE fuel development programs including the Accident Tolerant Fuels (ATF) program that sponsored the first modern fueled test to be performed in TREAT using the MARCH system. Since the design was modular in nature, it was straightforward for other sources to adopt and mature viable test modules while the LDRD project continued concurrently for two more years in conceptualizing and demonstrating the viability of other innovative modules. Many of these modules were adopted for continued development and irradiation under the Advanced Fuels Campaign and other direct sources. This report summarizes the MARCH modules that were conceptualized, designed, and deployed to date with the primary aim of providing reference information to future experiment designers.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Thermal-hydraulic and Fuel Performance Scoping Studies of a Flowing Water Capsule in TREAT

The restart of the Transient Reactor Test (TREAT) facility has provided a much needed capability for integral transient testing of nuclear fuel. This testing is necessary to qualify new fuel concepts such as those developed under the Accident Tolerant Fuel (ATF) program, increasing the burnup limit of light water reactor (LWR) fuels, or a variety of other programs under the Advanced Fuels Campaign (AFC). The ATF campaign has been the main driver behind the development and implementation of a variety of capsules for TREAT experiments. The Separate-Effect Test Holder (SETH) was a dry capsule that enabled testing of ATF concepts under reactivity-initiated accident (RIA) heating conditions. Following SETH, the Static Environment Rodlet Transient Test Apparatus (SERTTA) was developed to enable RIA testing in a static water environment. In efforts to support the need for future Loss-of-Coolant Accident (LOCA) tests, the Transient Water Irradiation System for TREAT (TWIST) capsule has been developed that allows for water to drain from around the fuel rod and lower the pressure to simulate LOCA conditions. All these capsules that have been developed for LWR fuel testing all lack the capability for forced convective cooling which in some applications may limit their ability to test under prototypic conditions. A design and modeling effort has been started to modify the TWIST capsule by adding a flow tube and impeller that can create flowing coolant conditions for the fuel rod. RELAP5-3D and BISON models are being used to study the differences between RIA, LOCA, Anticipated Operational Occurrences (AOO), LWR power cycling, and other transient scenarios under flowing conditions capable in the flowing capsule and the current stagnant water capsules (SERTTA and TWIST). The scoping study will provide guidance on the needed capabilities for the flowing capsule and the limitations of the currently developed capsule for LWR testing in TREAT.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Remote Home Energy Score Assessments (Feasibility Study)

The delivery of Home Energy Scores (HES) has been significantly impacted over the last year by the recent pandemic and ongoing limitations to person-to-person interactions. There are also historic challenges in providing HES to more remote geographies where assessor infrastructure is not in place. Alternative approaches to in-person, on-site home energy assessments could help address these current restrictions, while also potentially providing opportunities for the efficient delivery of HES in certain use cases after COVID-related restrictions are lifted. From the program administrator’s perspective, there needs to be confidence that the remote scores closely match what they would have been if the assessment had been performed on-site. The recommendations shown on a report generated from a remote score should closely match those of an onsite assessment. A remote assessment should be an option for all HES Partners and have direction on how to deliver those scores. From the HES partner’s and assessor’s perspective, there needs to be understanding of what level of experience is needed, what system infrastructure is required, the time expenditure of the remote assessment process, and the limitations of a remote assessment. From the homeowner’s perspective, there needs to be an awareness and comfort with the time commitment, the level of knowledge of the home, the equipment needed, and any physical requirements of the remote assessment process. During this study, Earth Advantage assessed methods for delivering Home Energy Score assessments remotely through web-based technology platforms and resident interaction in a diverse array of home types in different geographic locations. Earth Advantage developed remote assessment test protocols and integrated those testing protocols into existing Home Energy Score programs being overseen by USDOE Home Energy Score partners New York State Energy Research & Development Authority (NYSERDA), the Oregon Department of Energy (ODOE), and the City of Portland (PDX). Earth Advantage staff acted as the Remote assessor and gathered HES data remotely during the video sessions with participants. Authorized Home Energy Score assessors performed the onsite assessments that were then used to compare with the remote assessment data. This allowed the research to effectively test the efficacy of various remote assessment approaches in a diverse array of home-types. Earth advantage identified the key components of a remote assessment infrastructure which included Remote Home Energy Score Assessments Page vi processes, tools, services, methods and mechanisms that would better enable remote assessments. This report details methods, results, and findings of the HES remote assessment research. In addition, the report provides recommendations and best practices that could be used as guidance for the Home Energy Score administrator and the HES partners seeking to effectively conduct remote assessments.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Post-Irradiation Examination of Zircaloy-4 Samples in Target Capsules and Initiation of Bending Fatigue Testing for Used Nuclear Fuel Vibration Integrity Investigations (FY 2013 Summary Report)

This report documents ongoing work performed at Oak Ridge National Laboratory (ORNL) for the Department of Energy, Office of Fuel Cycle Technology Used Fuel Disposition Campaign (UFDC), and satisfies the deliverable for milestone M2FT-13OR0805041, “Data Report on Hydrogen Doping and Irradiation in HFIR.” This work is conducted under WBS 1.02.08.05, Work Package FT-13OR080504 ST “Storage and Transportation-Experiments – ORNL.” The objectives of work packages that make up the S&T Experiments Control Account are to conduct the separate effects tests (SET) and small-scale tests that have been identified in the Used Nuclear Fuel Storage and Transportation Data Gap Prioritization (FCRD-USED-2012-000109). In FY 2013, the R&D focused on cladding and container issues and small-scale tests as identified in Sections A-2.9 and A-2.12 of the prioritization report.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Absolute Dosimetry Model of the University of Washington Clinical Neutron Therapy System (CNTS)

The University of Washington (UW) Clinical Neutron Therapy System (CNTS) generates a fast neutron beam using 50.5 MeV protons incident on a beryllium target. The CNTS is mainly used for fast neutron therapy in the treatment of cancer but is also used for radiation effects testing and the production of rare isotopes, or isotopes with a short half-life, for medical imaging and therapy. The accelerator and treatment head is modeled using the MCNP6 Monte Carlo code to enable beam characterization (neutron and photon fluence, linear energy transfer, secondary particle production), study the behavior of neutron dosimeters and ionization chamber (IC) responses, and to conduct first principle studies of the relative biological effectiveness (RBE) of fast neutrons compared to {sup 60}Co γ-rays. Measurements of neutron dose in selected CNTS fields were made using a model-17 ion chamber (IC-17) flowing methane-based, tissue-equivalent (TE) gas. As a first approximation, we compared IC-17 measurements to the MCNP calculated dose in a thin layer of water at selected locations along the central axis of the beam. To examine the impact of the composition of the chamber fill-gas and the chamber design characteristics, we also developed a high-resolution (∼ 50 μm) MCNP model of the IC-17 from a computerized tomography (CT) scan. Initial results indicate that the dose response of the IC-17 ion chamber is up to 30% larger (smaller?) compared to the dose to water for neutrons with energies >20 MeV. Differences in chamber and water response as large as 800% occur for neutrons with kinetic energies below 1 keV. The simulations of IC-17 response (and dose to water) for CNTS fast neutron spectra match measured doses within 4.6% for all field sizes and irradiation geometries considered. This reported studies provide additional evidence establishing use of the IC-17 ion chamber model or a thin layer of water as a reasonable surrogate for CNTS fast neutron dose calculations.

61 RADIATION PROTECTION AND DOSIMETRY↗

Optimization of a Lethal, Combat-Relevant Model of Sterile Inflammation in Mice for Drug Candidate Screening

ABSTRACT Introduction Extensive trauma, commonly seen in wounded military Service Members, often leads to a severe sterile inflammation termed systemic inflammatory response syndrome (SIRS), which can progress to multiple organ dysfunction syndrome (MODS) and death. MODS is a serious threat to wounded Service Members, historically causing 10% of all deaths in trauma admissions at a forward deployed combat hospital. The importance of this problem will be exacerbated in large-scale combat operations, in which evacuation will be delayed and care of complex injuries at lower echelons of care may be prolonged. The main goal of this study was to optimize an existing mouse model of lethal SIRS/MODS as a therapeutic screening platform for the evaluation of immunomodulatory drugs. Materials and Methods Male C57BL/6 mice were euthanized, and the bones and muscles were collected and blended into a paste termed tissue–bone matrix (TBX). The TBX at 12.5%–20% relative to body weight of each recipient mouse was implanted into subcutaneous pouches created on the dorsum of anesthetized animals. Mice were observed for clinical scores for up to 48 hours postimplantation and euthanized at the preset point of moribundity. To test effects of anesthetics on TBX-induced mortality, animals received isoflurane or ketamine/xylazine (K/X). In a separate set of studies, mice received TBX followed by intraperitoneal injection with 20 mg/kg or 40 mg/kg Eritoran or a placebo carrier. All Eritoran studies were performed in a blinded fashion. Results We observed that K/X anesthesia significantly increased the lethality of the implanted TBX in comparison to inhaled anesthetics. Although all the mice anesthetized with isoflurane and implanted with 12.5% TBX survived for 24 hours, 60% of mice anesthetized with K/X were moribund by 24 hours postimplantation. To mimic more closely the timing of lethal SIRS/MODS following polytrauma in human patients, we extended observation to 48 hours. We performed TBX dose–response studies and found that as low as 15%, 17.5%, and 20% TBX caused moribundity/mortality in 50%, 80%, and 100% mice, respectively, over a 48-hour time period. With 17.5% TBX, we tested if moribundity/mortality could be rescued by anti-inflammatory drug Eritoran, a toll-like receptor 4 antagonist. Neither 20 mg/kg nor 40 mg/kg doses of Eritoran were found to be effective in this model. Conclusions We optimized a TBX mouse model of SIRS/MODS for the purpose of evaluating novel therapeutic interventions to prevent trauma-related pathophysiologies in wounded Service Members. Negative effects of K/X on lethality of TBX should be further evaluated, particularly in the light of widespread use of ketamine in treatment of pain. By mimicking muscle crush, bone fracture, and necrosis, the TBX model has pleiotropic effects on physiology and immunology that make it uniquely valuable as a screening tool for the evaluation of novel therapeutics against trauma-induced SIRS/MODS.

General & Internal Medicine↗

Multiple-metal exposure, diet, and oxidative stress in Uruguayan school children

Highlights: • In 6–8 year-old children, we examined associations between urinary concentrations of arsenic, cadmium, and lead, and urinary F{sub 2}–8α isoprostane and 8-hydroxy-2-deoxy-guanosine (8-OHdG). • Even at low-level, each doubling in urinary arsenic concentrations was associated with ~ 10 ng/mL higher 8-OHdG concentratio. • An indicator of mixture of the three metals was associated with higher 8-OHdG concentrations. • We found no effect modification by children's dietary antioxidant intake. Oxidative stress (OS) is an important consequence of exposure to toxic metals but it is unclear to what extent low-level metal exposures contribute to OS in children. We examined the cross-sectional association between urinary concentrations of arsenic (As), cadmium (Cd), and lead (Pb) and urinary markers of OS: F{sub 2}–8α isoprostane and 8-hydroxy-2-deoxy-guanosine (8-OHdG). We also tested effect modification by dietary intakes. Of the 211 children aged 6–8 years living in Montevideo who were eligible for the study because they had at least one OS marker measured via ELISA, 143 were included in a complete-case analysis. Urinary metals were measured with inductively coupled plasma mass spectrometry (ICP-MS: Pb, Cd) and high-performance liquid chromatography online with hydride generation ICP-MS (As-metabolites); concentrations were log{sub 2}-transformed. All urinary markers were adjusted for specific gravity of urine. Two 24-h dietary recalls were conducted to estimate children's dietary intakes, including total fruit and vegetable consumption and vitamin C, zinc and fiber intake. Ordinary least square (OLS) and weighted quantile sum (WQS) regressions were used to estimate the association between metals and each OS marker as outcome. Metal exposure was generally low: median urinary As, Cd, Pb 9.6 μg/L, 0.06 μg/L and 1.9 μg/L, respectively. Median 8-isoprostane concentration was 1.1 and 8-OHdG 39.6 ng/mL. Log{sub 2}-transformed urinary As concentrations were positively associated with 8-OHdG concentrations (10.90 [3.82, 17.97]) in covariate-adjusted OLS models which also took account of exposure to Cd and Pb. In WQS, a mixture index was also associated with higher 8-OHdG (8.71 [1.12, 16.3] for each 25% increase in index value), mostly driven by As exposure. There was little evidence of effect modification by dietary antioxidants. In sum, even at low-level, As exposure is associated with detectable oxidative damage to the DNA.

54 ENVIRONMENTAL SCIENCES↗

Advanced Concepts for Dry Storage Cask Thermal-Hydraulic Testing

The purpose of this report is to review technical issues relevant to the performance evaluation of dry storage systems during vacuum drying and long-term storage operations. It also provides updates on experimental components under development that are vital for pursuing advanced studies. Validation of the extent of water removal in a multi-assembly dry storage system using an industrial vacuum drying procedure is needed, as operational conditions leading to incomplete drying may have potential impacts on the fuel, cladding, and other components in the system. Water remaining in canisters/casks upon completion of vacuum drying can lead to cladding corrosion, embrittlement, and breaching, as well as fuel degradation. Therefore, additional information is needed to evaluate the potential impacts of water retention on extended long-term dry storage. A general lack of data and experience modeling the drying process necessitates the testing of advanced concepts focused on the simulation of industrial vacuum drying. Smaller-scale tests that incorporate relevant physics and well-controlled boundary conditions are necessary to provide insight and guidance to the modeling of prototypic systems undergoing drying processes. This report describes the development and testing of waterproof, electrically-heated spent fuel rod simulators as a proof of concept to enable experimental simulation of the entire dewatering and drying process. This report also describes the preliminary development of specially-designed, unheated mock fuel rods for monitoring internal rod pressures and studying water removal from simulated failed fuel rods. A variety of moisture monitoring instrumentation is also being considered and will be downselected for the tracking of dewpoints of gas samples. The effects of cladding oxidation and crud on water retention in dry storage systems can be explored via separate effects tests (SETs) that would measure chemisorbed and physisorbed water content on cladding samples. The concepts listed above will be incorporated into an advanced dry cask simulator with multiple fuel assemblies in order to account for important inter-assembly heat-transfer physics. Plans are described for harvesting up to five full-length 5x5 laterally truncated assemblies from commercial 17x17 PWR skeleton components with the goal of constructing this simulator.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗