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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 217 records · Page 12

Life sciences passive GN2 freezer thermal performance test

Thermal performance tests that were conducted on the life sciences passive GN2 freezer project are summarized as well as the improvements to the freezers to improve the thermal performance of the containers. Procedures were developed, based upon these tests, to initially charge the freezers with LN2 and verify that the freezer performance is adequate for the mission duration. Improvements were made to the corvac sample tube to limit the amount of breakage due to thermal expansion of the liquid during freezing. A method of verifying the freezer vacuum insulative integrity was defined as well as a procedure for refurbishment of the internal vacuum level. Freezer modifications were made to ease the reevacuation of the containers. The orientation of the freezer in a 1-G environment, after being charged, had to remain in a vertical position. The LN2 boiloff rate increased significantly in a horizontal position. This resulted in a stowage definition in the spacecraft prior to launch. Functional testing, using the SL-1 mission timeline showed that the freezer will maintain samples in the frozen state for the duration of the mission.

Belshaw, G. W.↗

Life sciences experiments on the space shuttle

The facilities afforded by the space shuttle/Spacelab to conduct life science experiments are described. Laboratory arrangement, specimen holding, and instrumentation are discussed.

Johnson, R. D.↗

The design and development of a release mechanism for space shuttle life-science experiments

The design, development, and testing of a release mechanism for use in two life science experiments on the Spacelab 1, 4, and D1 missions is described. The mechanism is a self latching ball lock device actuated by a linear solenoid. An unusual feature is the tapering of the ball lock plunger to give it a near constant breakout force for release under a wide range of loads. The selection of the design, based on the design requirements, is discussed. A number of problems occurred during development and test, including problems caused by human factors that became apparent after initial delivery for crewtraining sessions. These problems and their solutions are described to assist in the design and testing of similar mechanisms.

Jones, H. M.↗

USSR space life sciences digest, issue 27

This is the twenty-fifth issue of NASA's Space Life Sciences Digest. It contains abstracts of 30 journal papers or book chapters published in Russian and of 2 Soviet monographs. Selected abstracts are illustrated with figures and tables from the original. The abstracts in this issue have been identified as relevant to 18 areas of space biology and medicine. These areas include: adaptation, aviation medicine, biological rhythms, biospherics, botany, cardiovascular and respiratory systems, endocrinology, enzymology, exobiology, habitability and environmental effects, hematology, immunology, metabolism, musculoskeletal system, neurophysiology, radiobiology, and space medicine. A Soviet book review of a British handbook of aviation medicine and a description of the work of the division on aviation and space medicine of the Moscow Physiological Society are also included.

Stone, Lydia Razran↗

Digest of Russian Space Life Sciences, issue 33

This is the thirty-third issue of NASA's USSR Space Life Sciences Digest. It contains abstracts of 55 papers published in Russian journals. The abstracts in this issue have been identified as relevant to the following areas of space biology and medicine: biological rhythms, body fluids, botany, cardiovascular and respiratory systems, developmental biology, endocrinology, equipment and instrumentation, gastrointestinal system, genetics, hematology, human performance, metabolism, microbiology, musculoskeletal system, neurophysiology, nutrition, operational medicine, psychology, radiobiology, and reproductive system.

Stone, Lydia Razran↗

Advanced Technologies for Space Life Science Payloads on the International Space Station

SENSORS 2000! (S2K!) is a specialized, high-performance work group organized to provide advanced engineering and technology support for NASA's Life Sciences spaceflight and ground-based research and development programs. In support of these objectives, S2K! manages NASA's Advanced Technology Development Program for Biosensor and Biotelemetry Systems (ATD-B), with particular emphasis on technologies suitable for Gravitational Biology, Human Health and Performance, and Information Technology and Systems Management. A concurrent objective is to apply and transition ATD-B developed technologies to external, non-NASA humanitarian (medical, clinical, surgical, and emergency) situations and to stimulate partnering and leveraging with other government agencies, academia, and the commercial/industrial sectors. A phased long-term program has been implemented to support science disciplines and programs requiring specific biosensor (i.e., biopotential, biophysical, biochemical, and biological) measurements from humans, animals (mainly primates and rodents), and cells under controlled laboratory and simulated microgravity situations. In addition to the technology programs described above, NASA's Life and Microgravity Sciences and Applications Office has initiated a Technology Infusion process to identify and coordinate the utilization and integration of advanced technologies into its International Space Station Facilities. This project has recently identified a series of technologies, tasks, and products which, if implemented, would significantly increase the science return, decrease costs, and provide improved technological capability. This presentation will review the programs described above and discuss opportunities for collaboration, leveraging, and partnering with NASA.

Hines, John W.↗

USSR Space Life Sciences Digest, issue 21

This is the twenty-first issue of NASA's USSR Space Life Sciences Digest. It contains abstracts of 37 papers published in Russian language periodicals or books or presented at conferences and of a Soviet monograph on animal ontogeny in weightlessness. Selected abstracts are illustrated with figures and tables from the original. A book review of a work on adaptation to stress is also included. The abstracts in this issue have been identified as relevant to 25 areas of space biology and medicine. These areas are: adaptation, biological rhythms, body fluids, botany, cardiovascular and respiratory systems, cytology, developmental biology, endocrinology, enzymology, equipment and instrumentation, exobiology, gravitational biology, habitability and environmental effects, hematology, human performance, life support systems, mathematical modeling, metabolism, microbiology, musculoskeletal system, neurophysiology, operational medicine, perception, psychology, and reproductive system.

Hooke, Lydia Razran↗

A life sciences Spacelab mission simulation

The paper describes the purposes of a seven-day simulated life-sciences mission conducted in a Spacelab simulator. A major objective was the evaluation of in-orbit Spacelab operations and those mission control support functions which will be required from the Payload Operations Center. Tested equipment and procedures included experiment racks, common operational research equipment, commercial off-the-shelf equipment, experiment hardware interfaces with Spacelab, experiment data handling concepts, and Spacelab trash management.

Mason, J. A.↗

Results of the Life Sciences DSOs Conducted Aboard the Space Shuttle 1981-1986

Results are presented for a number of life sciences investigations sponsored by the Space Biomedical Research Institute at the NASA Lyndon B. Johnson Space Center and conducted as Detailed Supplementary Objectives (DSOs) on Space Shuttle flights between 1981 and 1986. An introduction and a description of the DSO program are followed by summary reports on the investigations. Reports are grouped into the following disciplines: Biochemistry and Pharmacology, Cardiovascular Effects and Fluid Shifts, Equipment Testing and Experiment Verification, Microbiology, Space Motion Sickness, and Vision. In the appendix, the status of every medical/life science DSO is presented in graphical form, which enables the flight history, the number of subjects tested, and the experiment results to be reviewed at a glance.

Vestibular Research↗

USSR Space Life Sciences Digest, Issue 26

This is the twenty-sixth issue of NASA's USSR Space Life Sciences Digest. It contains abstracts of 35 journal papers or book chapters published in Russian and of 8 Soviet books. In addition, the proceedings of an Intercosmos conference on space biology and medicine are summarized.

Stone, Lydia Razran↗

USSR Space Life Sciences Digest, issue 32

This is the thirty-second issue of NASA's USSR Space Life Sciences Digest. It contains abstracts of 34 journal or conference papers published in Russian and of 4 Soviet monographs. Selected abstracts are illustrated with figures and tables from the original. The abstracts in this issue have been identified as relevant to 18 areas of space biology and medicine. These areas include: adaptation, aviation medicine, biological rhythms, biospherics, cardiovascular and respiratory systems, developmental biology, exobiology, habitability and environmental effects, human performance, hematology, mathematical models, metabolism, microbiology, musculoskeletal system, neurophysiology, operational medicine, and reproductive system.

Stone, Lydia Razran↗

A Decade of Life Sciences Experiment Unique Equipment Development for Spacelab and Space Station, 1990-1999

Ames Research Center's Life Sciences Division has developed and flown an extensive array of spaceflight experiment unique equipment (EUE) during the last decade of the twentieth century. Over this ten year span, the EUE developed at ARC supported a vital gravitational biology flight research program executed on several different platforms, including the Space Shuttle, Spacelab, and Space Station Mir. This paper highlights some of the key EUE elements developed at ARC and flown during the period 1990-1999. Resulting lessons learned will be presented that can be applied to the development of similar equipment for the International Space Station.

Savage, Paul D.↗

Life Sciences Implications of Lunar Surface Operations

The purpose of this report is to document preliminary, predicted, life sciences implications of expected operational concepts for lunar surface extravehicular activity (EVA). Algorithms developed through simulation and testing in lunar analog environments were used to predict crew metabolic rates and ground reaction forces experienced during lunar EVA. Subsequently, the total metabolic energy consumption, the daily bone load stimulus, total oxygen needed, and other variables were calculated and provided to Human Research Program and Exploration Systems Mission Directorate stakeholders. To provide context to the modeling, the report includes an overview of some scenarios that have been considered. Concise descriptions of the analog testing and development of the algorithms are also provided. This document may be updated to remain current with evolving lunar or other planetary surface operations, assumptions and concepts, and to provide additional data and analyses collected during the ongoing analog research program.

Chappell, Steven P.↗

Results of Life Sciences DSOs Conducted aboard the Space Shuttle: 1988-1990

Results are presented for a collection of life sciences investigations sponsored by the Space Biomedical Research Institute and Biomedical Research Operations at the NASA Lyndon B. Johnson Space Center and conducted as Detailed Supplementary Objectives (DSOs) on Space Shuttle flights between 1988 and 1990. Reports were grouped into grouped into four primary sections: Orthostatic Function, Neurophysiology, Biomedical Physiology, and Radiation Monitoring. The DSOs included in this report are: - DSO 460: Changes in Total Body Water During Space Flight - DSO 466: Pre- and Postflight Cardiovascular Assessment/Interim Report - DSO 467: Influence of Weightlessness of Baroreflex Function - DSO 459: Otolith Tilt-Translation Reinterpretation - DSO 450: Salivary Cortisol Levels During the Acute Phases of Space Flight - DSO 458: In-flight Pharmacokinetics of Acetaminophen in Saliva - DSO 469A: Low Earth Orbit Radiation Dose Distribution in a Phantom Head - DSO 469B: Active Dosimetric Measurements on Shuttle Flights/Interim Report - DSO 469C: Neutron Spectrum and Dose-Equivalent in Shuttle Flights During Solar Maximum

Carolyn S Leach↗

Space Station Centrifuge: A Requirement for Life Science Research

A centrifuge with the largest diameter that can be accommodated on Space Station Freedom is required to conduct life science research in the microgravity environment of space. (This was one of the findings of a group of life scientists convened at the University of California, Davis, by Ames Research Center.) The centrifuge will be used as a research tool to understand how gravity affects biological processes; to provide an on-orbit one-g control; and to assess the efficacy of using artificial gravity to counteract the deleterious biological effect of space flight. The rationale for the recommendation and examples of using ground-based centrifugation for animal and plant acceleration studies are presented. Included are four appendixes and an extensive bibliography of hypergravity studies.

Smith, Arthur H.↗

The NASA Ames Life Sciences Data Archive: Biobanking for the Final Frontier

The NASA Ames Institutional Scientific Collection involves the Ames Life Sciences Data Archive (ALSDA) and a biospecimen repository, which are responsible for archiving information and non-human biospecimens collected from spaceflight and matching ground control experiments. The ALSDA also manages a biospecimen sharing program, performs curation and long-term storage operations, and facilitates distribution of biospecimens for research purposes via a public website (https:lsda.jsc.nasa.gov). As part of our best practices, a tissue viability testing plan has been developed for the repository, which will assess the quality of samples subjected to long-term storage. We expect that the test results will confirm usability of the samples, enable broader science community interest, and verify operational efficiency of the archives. This work will also support NASA open science initiatives and guides development of NASA directives and policy for curation of biological collections.

Biobank↗

USSR Space Life Sciences Digest. Index to issues 5-9

An index to issues 5 through 9 of the USSR Space Life Sciences Digest is provided in two sections. The first section lists bibliographic citations of abstracts contained in the Digest issues covered, grouped by topic area categories. Cross references to other relevant abstracts in different categories are also provided. The second section provides a key word index for the same set of abstracts.

Hooke, Lydia Razran↗