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At least 217 records · Page 12

Data correlation and analysis of arc tunnel and wind tunnel tests of RSI joints and gaps, phase 2. Volume 1: Technical report

Heat transfer data measured in gaps representative of those being employed for joints in the space shuttle reusable surface insulation (RSI) thermal protection systems (TPS) were assimilated, analyzed, and correlated. Several types of gap were investigated with emphasis on simple butt joints. Gap widths ranged from 0.0 to 0.76 cm and depths ranged from 1 to 6 cm. Laminar, transitional, and turbulent boundary layer flows over the gap opening were investigated. The angle between gap axis and external flow was varied between 0 and pi/2 radians. The contoured cross section gap performed significantly better than all other wide gaps and slightly better than all other narrow gap geometries. Three dimensional heating variations were observed within gaps in the absence of external flow pressure gradients. Interactions between heating within gaps and heating of adjacent top tile surfaces were observed. Gaps aligned with the flow were observed to promote boundary layer transition. Heat transfer correlation equations were obtained for many of the tests. The TPS thickness requirements with and without gaps were computed for a current shuttle entry trajectory. Experimental data employed in the study are summarized. A description of each test facility, run schedule and test conditions, model descriptive information, and heat flux data are included.

Cristensen, H. E.↗

CORRLA-RS

The CORRLA-RS package provides a suite of statistical methods for sampling multidimensional distributions and to conduct sensitivity and correlation analysis of large scale data in the Rust programming language. The software provides a unique solution to multidimensional constrained sampling problems utilizing a combination of parallelized Markov Chain Monte Carlo methods and traditional rejection sampling. The sensitivity and correlation analysis methods are backed by a high performance randomized singular value decomposition implementation which enables datasets larger than the random access memory (RAM) size to be analyzed. Additionally, CORRLA-RS implements the active subspace identification method using a KD-Tree and the randomized singular value decomposition acting in concert.

Gurecky, William [Oak Ridge National Laboratory (O↗

Correlation Function Analysis of Fiber Networks: Implications for Thermal Conductivity

The heat transport in highly porous fiber structures is investigated. The fibers are supposed to be thin, but long, so that the number of the inter-fiber connections along each fiber is large. We show that the effective conductivity of such structures can be found from the correlation length of the two-point correlation function of the local conductivities. Estimation of the parameters, determining the conductivity, from the 2D images of the structures is analyzed.

Martinez-Garcia, Jorge↗

Correlated Nanoscale Analysis of the Emission from Wurtzite versus Zincblende (In,Ga)As/GaAs Nanowire Core–Shell Quantum Wells

Although the properties of wurtzite GaAs have been extensively researched during the past decade, little is known about the influence of the crystal polytype on ternary (In,Ga)As quantum well structures. We address this concern with a unique combination of correlated, spatially resolved measurement techniques on core–shell nanowires that contain extended segments of both the zincblende and wurtzite polytypes. Cathodoluminescence hyperspectral imaging reveals a blue-shift of the quantum well emission energy by 75 ± 15 meV in the wurtzite polytype segment. Nanoprobe X-ray diffraction and atom probe tomography enable k·p calculations for the specific sample geometry to reveal two comparable contributions to this shift. First, there is a 30% drop in In mole fraction going from the zincblende to the wurtzite segment. Second, the quantum well is under compressive strain, which has a much stronger impact on the hole ground state in the wurtzite than in the zincblende segment. Our findings illustrate the role of the crystal structure in tuning the emission of (In,Ga)As quantum wells and pave the way to exploit the possibilities of three-dimensional band gap engineering in core–shell nanowire heterostructures. At the same time, we have demonstrated an advanced characterization toolkit for the investigation of semiconductor nanostructures.

(In,Ga)As quantum well↗

Structure-Activity Relationships for Rates of Aromatic Amine Oxidation by Manganese Dioxide

New energetic compounds are designed to minimize their potential environmental impacts, which includes their transformation and the fate and effects of their transformation products. The nitro groups of energetic compounds are readily reduced to amines, and the resulting aromatic amines are subject to oxidation and coupling reactions. Manganese dioxide (MnO 2 ) is a common environmental oxidant and model system for kinetic studies of aromatic amine oxidation. Here in this study, a training set of new and previously reported kinetic data for the oxidation of model and energetic-derived aromatic amines was assembled and subjected to correlation analysis against descriptor variables that ranged from general purpose [Hammett $\sigma$ constants ($\sigma^-$), pK a s of the amines, and energies of the highest occupied molecular orbital (E HOMO )] to specific for the likely rate-limiting step [one-electron oxidation potentials (E ox )]. The selection of calculated descriptors (pK a ), E HOMO , and E ox ) was based on validation with experimental data. All of the correlations gave satisfactory quantitative structure-activity relationships (QSARs), but they improved with the specificity of the descriptor. The scope of correlation analysis was extended beyond MnO 2 to include literature data on aromatic amine oxidation by other environmentally relevant oxidants (ozone, chlorine dioxide, and phosphate and carbonate radicals) by correlating relative rate constants (normalized to 4-chloroaniline) to E HOMO (calculated with a modest level of theory).

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Long-wavelength Magnetic and Gravity Anomaly Correlations of Africa and Europe

Preliminary MAGSAT scalar magnetic anomaly data were compiled for comparison with long-wavelength-pass filtered free-air gravity anomalies and regional heat-flow and tectonic data. To facilitate the correlation analysis at satellite elevations over a spherical-Earth, equivalent point source inversion was used to differentially reduce the magnetic satellite anomalies to the radial pole at 350 km elevation, and to upward continue the first radial derivative of the free-air gravity anomalies. Correlation patterns between these regional geopotential anomaly fields are quantitatively established by moving window linear regression based on Poisson's theorem. Prominent correlations include direct correspondences for the Baltic Shield, where both anomalies are negative, and the central Mediterranean and Zaire Basin where both anomalies are positive. Inverse relationships are generally common over the Precambrian Shield in northwest Africa, the Basins and Shields in southern Africa, and the Alpine Orogenic Belt. Inverse correlations also presist over the North Sea Rifts, the Benue Rift, and more generally over the East African Rifts. The results of this quantitative correlation analysis support the general inverse relationships of gravity and magnetic anomalies observed for North American continental terrain which may be broadly related to magnetic crustal thickness variations.

Vonfrese, R. R. B.↗

Long-wavelength magnetic and gravity anomaly correlations on Africa and Europe

Preliminary MAGSAT scalar magnetic anomaly data were compiled for comparison with long-wavelength-pass filtered free-air gravity anomalies and regional heat-flow and tectonic data. To facilitate the correlation analysis at satellite elevations over a spherical-Earth, equivalent point source inversion was used to differentially reduce the magnetic satellite anomalies to the radial pole at 350 km elevation, and to upward continue the first radial derivative of the free-air gravity anomalies. Correlation patterns between these regional geopotential anomaly fields are quantitatively established by moving window linear regression based on Poisson's theorem. Prominent correlations include direct correspondences for the Baltic shield, where both anomalies are negative, and the central Mediterranean and Zaire Basin where both anomalies are positive. Inverse relationships are generally common over the Precambrian Shield in northwest Africa, the Basins and Shields in southern Africa, and the Alpine Orogenic Belt. Inverse correlations also presist over the North Sea Rifts, the Benue Rift, and more generally over the East African Rifts. The results of this quantitative correlation analysis support the general inverse relationships of gravity and magnetic anomalies observed for North American continental terrain which may be broadly related to magnetic crustal thickness variations.

Vonfrese, R. R. B.↗

A Comment on the Suspected Solar Neutrino-Solar Activity Connection

Recently, it has been proposed that there exists a highly statistically significant (at greater than or equal to 98% level of confidence) relationship between Ar-37 production rate (viz., solar neutrinos) and the Ap geomagnetic index (viz., solar particles), based on the (chi)-square goodness-of-fit test and correlation analysis, for the interval 1970-1990. While a relationship between the two parameters, indeed, seems to be discernible, the strength of the relationship has been overstated. Instead of being significant at the afore-mentioned level of confidence, the relationship is found to be significant at only greater than or equal to 95% level of confidence, based on Yates' modification to the (chi)-square test for 2 x 2 contingency tables. Likewise, while correlation analysis yields a value of r = 0.2691, it is important to note that such a value suggests that only about 7% of the variance can be 'explained' by the inferred correlation and that the remaining 93% of the variance must be attributed to other sources.

Wilson, Robert M.↗

A comment on the suspected solar neutrino -- solar activity connection

Recently, it has been proposed that there exists a highly statistically significant (at greater than or equal to 98% level of confidence) relationship between Ar-37 production rate (namely, solar neutrinos) and the Ap geomagnetic index (namely, solar particles), based on the chi-square goodness-of-fit test and correlation analysis, for the interval 1970-1990. While a relationship between the two parameters, indeed, seems to be discernible, the strength of the relationship has been overstated. Instead of being significant at the afore-mentioned level of confidence, the relationship is found to be significant at only greater than or equal to 95% level of confidence, based on Yates' modification to the chi-square test for 2 x 2 contingency tables. Likewise, while correlation analysis yields a value of r = 0.2691, it is important to note that such a value suggests that only about 7% of the variance can be 'explained' by the inferred correlation and that the remaining 93% of the variance must be attributed to other sources.

Wilson, Robert M.↗

Orion MPCV Service Module Avionics Ring Pallet Testing, Correlation, and Analysis

The NASA Orion Multi-Purpose Crew Vehicle (MPCV) is being designed to replace the Space Shuttle as the main manned spacecraft for the agency. Based on the predicted environments in the Service Module avionics ring, an isolation system was deemed necessary to protect the avionics packages carried by the spacecraft. Impact, sinusoidal, and random vibration testing were conducted on a prototype Orion Service Module avionics pallet in March 2010 at the NASA Glenn Research Center Structural Dynamics Laboratory (SDL). The pallet design utilized wire rope isolators to reduce the vibration levels seen by the avionics packages. The current pallet design utilizes the same wire rope isolators (M6-120-10) that were tested in March 2010. In an effort to save cost and schedule, the Finite Element Models of the prototype pallet tested in March 2010 were correlated. Frequency Response Function (FRF) comparisons, mode shape and frequency were all part of the correlation process. The non-linear behavior and the modeling the wire rope isolators proved to be the most difficult part of the correlation process. The correlated models of the wire rope isolators were taken from the prototype design and integrated into the current design for future frequency response analysis and component environment specification.

Staab, Lucas↗

Cross-correlation image analysis for real-time single particle tracking

Accurately measuring the translations of objects between images is essential in many fields, including biology, medicine, chemistry, and physics. One important application is tracking one or more particles by measuring their apparent displacements in a series of images. Popular methods, such as the center of mass, often require idealized scenarios to reach the shot noise limit of particle tracking and, therefore, are not generally applicable to multiple image types. More general methods, such as maximum likelihood estimation, reliably approach the shot noise limit, but are too computationally intense for use in real-time applications. These limitations are significant, as real-time, shot-noise-limited particle tracking is of paramount importance for feedback control systems. To fill this gap, we introduce a new cross-correlation-based algorithm that approaches shot-noise-limited displacement detection and a graphics processing unit-based implementation for real-time image analysis of a single particle.

Instruments & Instrumentation↗

20 Meter Solar Sail Analysis and Correlation

This paper describes finite element analyses and correlation studies to predict deformations and vibration modes/frequencies of a 20-meter solar sail system developed by ATK Space Systems. Under the programmatic leadership of NASA Marshall Space Flight Center's In-Space Propulsion activity, the 20-meter solar sail program objectives were to verify the design, to assess structural responses of the sail system, to implement lessons learned from a previous 10-meter quadrant system analysis and test program, and to mature solar sail technology to a technology readiness level (TRL) of 5. For this 20 meter sail system, static and ground vibration tests were conducted in NASA Glenn Research Center's 100 meter diameter vacuum chamber at Plum Brook station. Prior to testing, a preliminary analysis was performed to evaluate test conditions and to determine sensor and actuator locations. After testing was completed, an analysis of each test configuration was performed. Post-test model refinements included updated properties to account for the mass of sensors, wiring, and other components used for testing. This paper describes the development of finite element models (FEM) for sail membranes and masts in each of four quadrants at both the component and system levels, as well as an optimization procedure for the static test/analyses correlation.

Taleghani, B. K.↗

LOX-related collagen crosslink changes act as an initiator of bone fragility in a ZDF rats model

Highlights: • Bone mechanical loss in type 2 diabetes is mainly restricted to the post-yield behavior. • Loss of insoluble collagen in the matrix phase is the initial cause of bone mechanical loss in type 2 diabetes. • The insoluble collagen amount in bone tissue is the positive regressor of bone post-yield behavior. • The expression of Lox and lox-like family are downregulated in bone tissue in type 2 diabetes. Diabetes mellitus type 2 (DM2) results in bone abnormalities that manifest as increased bone fragility. Bone consists of two phases, the mineral phase and the matrix phase, and disorders in both are seen in DM2. However, the phase in which DM2 mediated bone fragility is initiated is still unknown. In this study, a male Zucker diabetic fatty (fa/fa) (ZDF) rat model was used to investigate the underlying mechanism initiating DM2 mediated bone fragility. The fracture surface morphology, pre- and post-yield bone mechanical behavior, insoluble collagen volume, lysyl oxidase family (LOX) enzyme levels and correlation analysis was performed to determine the relationship between insoluble collagen and post-yield behavior. Four weeks after the induction of diabetes, insoluble collagen was decreased in only the matrix phase in diabetic rats. Consistently, mechanical testing of the bone showed changes only in post-yield behavior. Diabetic rats also had decreased levels of enzymes involved in insoluble collagen formation (LOX and LOXL1 families). Correlation analysis demonstrated that insoluble collagen was a positive regressor of post-yield displacement (R = 0.894, P P < 0.001). Together, these findings suggest that bone fragility in DM2 is initiated in the matrix phase and that the LOX family may play a critical part in the pathogenesis of DM2 mediated bone fragility.

60 APPLIED LIFE SCIENCES↗

Local Analysis-Test Correlation Of Tow-Steered Composite Shells With Small Cutouts

The prebuckling and postbuckling behavior of two composite tow-steered shells with small cutouts is assessed using nonlinear dynamic finite element analyses and compared in detail with experimental measurements. The cylindrical shells were manufactured without cutouts using an automated fiber placement system, where the shells’ fiber orientation angles vary continuously around the shell circumference from ±10 degrees on the axially stiff crown and keel, to ±45 degrees on the shear-stiff sides. The first shell with overlaps has laminate thickness variations on the crown and keel that result from application of all 24 tows during each pass of the fiber placement system. The second shell without overlaps uses the fiber placement system’s tow drop/add capability to achieve a more uniform shell wall thickness. An unreinforced cutout representing a passenger door on a commercial aircraft fuselage is machined into the side of each of the two shells. These shells with cutouts were tested in axial compression and buckled elastically in previous work. Detailed nonlinear finite element analysis results are compared with their corresponding measured local load-displacement and load-strain responses in prebuckling, at global buckling, and into a stable postbuckled state. Test data from displacement transducers, strain gages, and digital image correlation are extracted at the centers of the crown and keel, and at the middles of the top and left edges of the cutout. The overall agreement between these measured and analytical responses is excellent in prebuckling through global buckling, and very good from global buckling through postbuckling. As such, the excellent correlation observed here increases confidence in applying tow-steered composites in operational vehicles.

Composites↗

Local Analysis-Test Correlation Of Tow-Steered Composite Shells With Small Cutouts

The prebuckling and postbuckling behavior of two composite tow-steered shells with small cutouts is assessed using nonlinear dynamic finite element analyses and compared in detail with experimental measurements. The cylindrical shells were manufactured without cutouts using an automated fiber placement system, where the shells’ fiber orientation angles vary continuously around the shell circumference from ±10 degrees on the axially stiff crown and keel, to ±45 degrees on the shear-stiff sides. The first shell with overlaps has laminate thickness variations on the crown and keel that result from application of all 24 tows during each pass of the fiber placement system. The second shell without overlaps uses the fiber placement system’s tow drop/add capability to achieve a more uniform shell wall thickness. An unreinforced cutout representing a passenger door on a commercial aircraft fuselage is machined into the side of each of the two shells. These shells with cutouts were tested in axial compression and buckled elastically in previous work. Detailed nonlinear finite element analysis results are compared with their corresponding measured local load-displacement and load-strain responses in prebuckling, at global buckling, and into a stable postbuckled state. Test data from displacement transducers, strain gages, and digital image correlation are extracted at the centers of the crown and keel, and at the middles of the top and left edges of the cutout. The overall agreement between these measured and analytical responses is excellent in prebuckling through global buckling, and very good from global buckling through postbuckling. As such, the excellent correlation observed here increases confidence in applying tow-steered composites in operational vehicles.

Composites↗

Reversed Nanoscale Kirkendall Effect in Au–InAs Hybrid Nanoparticles

Metal–semiconductor hybrid nanoparticles (NPs) offer interesting synergistic properties, leading to unique behaviors that have already been exploited in photocatalysis, electrical, and optoelectronic applications. A fundamental aspect in the synthesis of metal–semiconductor hybrid NPs is the possible diffusion of the metal species through the semiconductor lattice. The importance of understanding and controlling the co-diffusion of different constituents is demonstrated in the synthesis of various hollow-structured NPs via the Kirkendall effect. Here, we used a postsynthesis room-temperature reaction between AuCl 3 and InAs nanocrystals (NCs) to form metal–semiconductor core–shell hybrid NPs through the “reversed Kirkendall effect”. In the presented system, the diffusion rate of the inward diffusing species (Au) is faster than that of the outward diffusing species (InAs), which results in the formation of a crystalline metallic Au core surrounded by an amorphous, oxidized InAs shell containing nanoscale voids. We used time-resolved X-ray absorption fine-structure (XAFS) spectroscopy to monitor the diffusion process and found that both the size of the Au core and the extent of the disorder of the InAs shell depend strongly on the Au-to-NC ratio. We have determined, based on multielement fit analysis, that Au diffuses into the NC via the kick-out mechanism, substituting for In host atoms; this compromises the structural stability of the lattice and triggers the formation of In–O bonds. These bonds were used as markers to follow the diffusion process and indicate the extent of degradation of the NC lattice. Time-resolved X-ray diffraction (XRD) was used to measure the changes in the crystal structures of InAs and the nanoscale Au phases. By combining the results of XAFS, XRD, and electron microscopy, we correlated the changes in the local structure around Au, As, and In atoms and the changes in the overall InAs crystal structure. This correlative analysis revealed a co-dependence of different structural consequences when introducing Au into the InAs NCs. Therefore, this study of diffusion effects in nanocrystals has relevance to powerful concepts in solid-state nanochemistry related to processes of cation exchange, doping reactions, and diffusion mechanisms.

36 MATERIALS SCIENCE↗

Long non-coding RNA CCAT1 promotes glioma cell proliferation via inhibiting microRNA-410

Background and aim: Long non-coding RNAs have been confirmed to play a critical role in various cancers. In the present study, the effect of long non-coding RNA (lncRNA) CCAT1 on glioma cell proliferation and its potential mechanism were investigated. Methods and results: Real-time PCR results showed that lncRNA-CCAT1 expression was significantly upregulated in glioma cancer tissues and cell lines compared with controls. After inhibiting CCAT1 expression in glioma cell line U251 with siRNA-CCAT1 (si-CCAT1), the cell viability and cell colony formation were decreased, the cell cycle was arrested in G1 phase, and the cell apoptosis was increased. As reported in bioinformatics software starbase2.0, a total of 22 microRNAs were potentially targeted by CCAT1. It was confirmed that miR-410 was altered most by si-CCAT1. After up-regulating CCAT1 expression in U251 cells, miR-410 level was decreased. Luciferase reporter assay confirmed that CCAT1 targeted miR-410. Correlation analysis showed that CCAT1 expression was negatively related to miR-410 expression in glioma cancer tissues. In addition, down-regulation of miR-410 reversed the inhibitory effect of si-CCAT1 on glioma proliferation. Conclusion: These data demonstrated that lncRNA-CCAT1 promoted glioma cell proliferation via inhibiting miR-410, providing a new insight about the pathogenesis of glioma proliferation. - Highlights: • lncRNA-CCAT1 expression was significantly upregulated in glioma cancer tissues and cell lines. • Correlation analysis showed that CCAT1 expression was negatively related to miR-410 expression in glioma cancer tissues. • Down-regulation of miR-410 reversed the inhibitory effect of si-CCAT1 on glioma proliferation.

60 APPLIED LIFE SCIENCES↗

Interpretation of ozone temperature correlations. II - Analysis of SBUV ozone data

In an effort to understand the behavior of ozone in the transition region, the terms in the perturbation continuity equation have been evaluated from solar backscattered ultraviolet ozone data, National Meteorological Center temperature data, and geostrophic winds derived from the temperature data at 2 mbar, winter 1978-1979. A linear parameterization is used to estimate the chemical source term. The perturbation ozone field calculated by integrating the net forcing evaluated from the data compares well with the measured perturbation ozone field. There are occasions during the winter when the sum of the dynamic terms is small due to cancellation, and the ozone and temperature perturbations are anticorrelated. The -1 correlation between the ozone and temperature perturbations does not necessarily imply that chemical forcing is dominant.

Douglass, A. R.↗