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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 217 records · Page 12

Proteogenomic insights suggest druggable pathways in endometrial carcinoma

We characterized a prospective endometrial carcinoma (EC) cohort containing 138 tumors and 20 enriched normal tissues using 10 different omics platforms. Targeted quantitation of two peptides can predict antigen processing and presentation machinery activity, and may inform patient selection for immunotherapy. Association analysis between MYC activity and metformin treatment in both patients and cell lines suggests a potential role for metformin treatment in non-diabetic patients with elevated MYC activity. PIK3R1 in-frame indels are associated with elevated AKT phosphorylation and increased sensitivity to AKT inhibitors. CTNNB1 hotspot mutations are concentrated near phosphorylation sites mediating pS45-induced degradation of β-catenin, which may render Wnt-FZD antagonists ineffective. Deep learning accurately predicts EC subtypes and mutations from histopathology images, which may be useful for rapid diagnosis. Overall, this study identified molecular and imaging markers that can be further investigated to guide patient stratification for more precise treatment of EC.

60 APPLIED LIFE SCIENCES↗

Instanton Effects in Euclidean vacuum, Real Time Production, and in the Light-front Wave Functions

Nontrivial topological structures of non-Abelian gauge fields were discovered in the 1970s. Instanton solutions, describing vacuum tunneling through topological barriers, have fermionic zero modes which are at the origin of ‘t Hooft effective Lagrangian. In the 1980s, instanton ensembles have been used to explain chiral symmetry breaking. In the 1990s, a large set of numerical simulations were performed deriving Euclidean correlation functions. The special role of scalar diquarks in nucleons and color superconductivity in dense quark matter has been elucidated. In these lectures, we discuss further developments of physics related to gauge topology. We show that the instanton–anti-instanton “streamline” configurations describe “sphaleron transitions” in high-energy collisions, which result in production of hadronic clusters with nontrivial topological/chiral charges. (They are not yet observed, but discussions of dedicated experiments at the LHC and RHIC are ongoing.) Another new direction is instanton effects in hadronic spectroscopy, both in the rest frame and on the light front. We will discuss their role in central and spin-dependent potentials, form factors and antiquark nuclear “sea”. Finally, we summarize the advances in the semiclassical theory of deconfinement, and chiral phase transitions at finite temperature, in QCD, and in some of its “deformed” versions.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Portable pallet weighing apparatus

An assembly for use with several like units in weighing the mass of a loaded cargo pallet supported by its trunnions has a bridge frame for positioning the assembly on a transportation frame carrying the pallet while straddling one trunnion of the pallet and its trunnion lock, and a cradle assembly for incrementally raising the trunnion. The mass at the trunnion is carried as a static load by a slidable bracket mounted upon the bridge frame for supporting the cradle assembly. The bracket applies the static loading to an electrical load cell symmetrically positioned between the bridge frame and the bracket. The static loading compresses the load cell, causing a slight deformation and a potential difference at load cell terminals which is proportional in amplitude to the mass of the pallet at the trunnion.

Day, R. M.↗

CCD With Back-Side Illumination And Charge Steering

Proposed charge-coupled device (CCD) imaging array of photodetectors has features of back-side-illuminated CCD and interline-transfer CCD. Photoelectrons generated near back surface and swept by electric fields toward front into collecting potential wells, not directly opposite that location. By suitable timing of control signals, charges from multiple image frames stored in rapid succession. Useful in imaging rapid transient phenomena as chemically reacting flows, with interframe intervals of microseconds.

Fossum, Eric R.↗

Evolution user requirements for the restructured space station

Space Station Freedom (SSF) is designed to be an Earth orbiting multidisciplinary R&D facility capable of evolving to accommodate a variety of potential uses. In order to identify SSF evolution requirement and define potential growth configurations, NASA-Langley is analyzing user resource requirements for the post-PMC time frame. The analysis goal is to define resource levels, including crew, power, and volume, which allow full utilization of SSF capabilities commensurate with minimum essential user requirements. Multiple scenarios were studied including core R&D and combined SEI plus R&D utilization. An analysis is presented of a core R&D utilization scenario. Included are discussions of resource allocation assumptions for specific R&D disciplines, user requirements trends, and growth resource projections. These preliminary results show total resource requirements of 13 crew, 150 kW power, and additional lab volume equivalent to a second U.S. lab module. Additionally, orthogonal growth structure was identified as required to support SSF systems and users.

Leath, K.↗

Hierarchical Strategy for Rapid Analysis Environment

A new philosophy is developed wherein the hierarchical definition of data is made use of in creating a better environment to conduct analyses of practical problems. This system can be adapted to conduct virtually any type of analysis, since this philosophy is not bound to any specific kind of analysis. It provides a framework to manage different models and its results and more importantly, the interaction between the different models. Thus, it is ideal for many types of finite element analyses like globalAoca1 analysis and those that involve multiple scales and fields. The system developed during the course of this work is just a demonstrator of the basic concepts. A complete implementation of this strategy could potentially make a major impact on the way analyses are conducted. It could considerably reduce the time frame required to conduct the analysis of real-life problems by efficient management of the data involved and reducing the human effort involved. It also helps in better decision making because of more ways to interpret the results. The strategy has been currently implemented for structural analysis, but with more work it could be extended to other fields of science when the finite element method is used to solve the differential equations numerically. This report details the work that has been done during the course of this project and its achievements and results. The following section discusses the meaning of the word hierarchical and the different references to the term in the literature. It talks about the development of the finite element method, its different versions and how hierarchy has been used to improve the methodology. The next section describes the hierarchical philosophy in detail and explains the different concepts and terms associated with it. It goes on to describe the implementation and the features of the demonstrator. A couple of problems are analyzed using the demonstrator program to show the working of the system. The two problems considered are two dimensional plane stress analysis problems. The results are compared with those obtained using conventional analysis. The different challenges faced during the development of this system are discussed. Finally, we conclude with suggestions for future work to add more features and extend it to a wider range of problems.

Whitcomb, John↗

High Temperature Transfer Molding Resins: Status of PETI-298 and PETI-330

Two phenylethynyl terminated oligomers designated PETI-298 and PETI-330 were developed at the NASA Langley Research Center and have emerged as leading candidates for composite applications requiring high temperature performance (i.e. greater than or equal to 288 C for 1000 hours) combined with the ability to be readily processed into composites without the use of an autoclave or complex/lengthy cure or post-cure cycle. These high performance/high temperature composites are potentially useful on advanced aerospace vehicles in structural applications and as aircraft engine components such as inlet frames and compressor vanes. The number designation (i.e. 298, 330) refers to the glass transition temperature in degrees Celsius as determined on neat resin cured for 1 hour at 371 C. The resins are processable by non-autoclave techniques such as resin transfer molding (RTM), vacuum assisted RTM (VARTM) and resin infusion (RI). Both resins exhibit low complex melt viscosities (0.1-10 poise) at 280 C and are stable for greater than or equal to 2 hours at this temperature. Typically, the resins are melted, de-gassed and infused or injected at 280 C and subsequently cured at 371 C for 1-2 hours. Virtually no volatiles are evolved during the cure process. The resin synthesis is straightforward and has been scaled-up to 25 kg batches. The chemistry of PETI-298 and PETI-330 and the RTM AS-4 and T-650 carbon fabric laminate properties, and those of BMI-5270 for comparison, are presented.

Connell, John W.↗

Neural network tracking and extension of positive tracking periods

Feature detectors have been considered for the role of supplying additional information to a neural network tracker. The feature detector focuses on areas of the image with significant information. Basically, if a picture says a thousand words, the feature detectors are looking for the key phrases (keypoints). These keypoints are rotationally invariant and may be matched across frames. Application of these advanced feature detectors to the neural network tracking system at JPL has promising potential. As part of an ongoing program, an advanced feature detector was tested for augmentation of a neural network based tracker. The advance feature detector extended tracking periods in test sequences including aircraft tracking, rover tracking, and simulated Martian landing. Future directions of research are also discussed.

feature extraction↗

The treatment of convected vortices in compressible potential flow

A method is described for incorporating line vortices into the three dimensional compressible potential flow equation. A modified Biot-Savart law is used to compute a vortical velocity field, which is added to the gradient of the potential to form a total velocity. A rapidly converging approximate factorization (AFZ) scheme is then used to compute a potential such that the modified potential flow equation as well as the appropriate boundary conditions, based on total velocity, are satisfied. As part of a coupled iteration procedure, the positions of the line vortices are computed so that they convect with the total flow. The method is used to compute the field due to a single line vortex convecting past a wing. This represents an approximation of the effect of a canard or other lifting surface ahead of the wing, which sheds a tip vortex. It is seen that the flow field is substantially modified by the passage of the vortex. Unlike Euler equation schemes, which are also used to compute these flows, the solutions exhibit no numerical diffusion: The convected vortices retain their initial upstream width. Euler solutions, on the other hand, involve a vorticity which is numerically convected in an Eulerian frame and, unless extensive adaptive grid refinement is used they result in vortices with spread as they convect. Also, the potential flow method requires approximately two orders of magnitude less computing time and much less computer storage than the Euler methods.

Steinhoff, J.↗

A vortex wake capturing method for potential flow calculations

A method is presented for modifying finite difference solutions of the potential equation to include the calculation of non-planar vortex wake features. The approach is an adaptation of Baker's 'cloud in cell' algorithm developed for the stream function-vorticity equations. The vortex wake is tracked in a Lagrangian frame of reference as a group of discrete vortex filaments. These are distributed to the Eulerian mesh system on which the velocity is calculated by a finite difference solution of the potential equation. An artificial viscosity introduced by the finite difference equations removes the singular nature of the vortex filaments. Computed examples are given for the two-dimensional time dependent roll-up of vortex wakes generated by wings with different spanwise loading distributions.

Murman, E. M.↗

Signatures of bulge triaxiality from kinematics in Baade's window

We study a sample of 62 Baade's Window, (l,b) = (1, -4)deg, K giants that have published proper motions, radial velocity, and metallicity. Using R(sub 0) = 8 kpc, we construct the velocity ellipsoids, namely the 3x3 velocity dispersion tensors, for the metal rich stars ((Fe/H) greater than or equal to 0) and metal poor stars ((Fe/H) less than or equal to -0.2). After diagonalizing the tensor, we find a vertex deviation characteristic of a nonaxisymmetric system. Eigenvalues for the two velocity ellipsoids (sigma(sub 1), sigma(sub 2), sigma(sub 3)) are (126, 89, 65) +/- 13 km/s for the metal rich sample and (154, 77, 83) +/- 25 km/s for the metal poor sample with their long axes pointing to two nearly perpendicular directions (l(sub v), b(sub v)) = (-65 +/- 9 deg, +14 +/- 9 deg) and (l(sub v), b(sub v)) = (25 +/- 14 deg, -11 +/- 14 deg), respectively. The vertex deviations of the velocity ellipsoids cannot be consistently explained by any oblate model. We are able to reject the hypothesis that the metal poor and metal rich populations are drawn from the same distribution at better than the 97% confidence level. We populate orbits in a realistic bar potential with a Gaussian velocity distribution, allowing us to simulate and interpret observations. We conclude that the data are consistent with a triaxial bulge pointing towards (l,b) with l less than 0 deg and b = 0 deg as suggested by earlier work on gas dynamics and the observed light distribution. We also predict that low latitude (absolute value of b less than or equal to 4 deg) bulge fields should show the vertex deviation more strongly and would therefore be the best locations for future proper motion studies. In the classification scheme of Athanassoula et al. (1983) the metal rich stars appear to occupy the B-family orbits which rotate in the prograde sense in the rest frame and have boxy shapes that are aligned with and supporting the bar. The metal poor stars in the sample lag behind the metal rich bulge and appear to occupy R-family orbits which rotate in the retrograde sense in the rest frame. They have nearly round loop shapes and are aligned perpendicularly to the bar, hence limit the triaxiality of the bar potential. The correlations between the metallicity and the orbit families can develop if the bulge forms dissipatively on a sufficiently long time scale. However, it is difficult to explain such correlations if most stars in the inner Galaxy form during the violent relaxation phase.

Zhao, Hongsheng↗

Multiframe X-ray diffraction on the OMEGA EP laser

A method of measuring multiple temporally resolved powder x-ray diffraction measurements during a single dynamic compression laser experiment has been demonstrated on the OMEGA EP laser. Up to four time-gated snapshots of the x-ray diffraction pattern are collected on an ultrafast x-ray framing camera with a 2θ scattering angle coverage of 48°–65° and 400-ps temporal resolution with the potential for 10°–160° and 200-ps resolution. X-ray diffraction snapshots capture the transformation to a high-pressure β phase in ramp-compressed Zr, constraining the atomic structure and pressure–density equation-of-state in a single shot. Here, this platform will be used to constrain transition pressures, understand the role of kinetics, and verify the existence of hysteresis and metastability on phase transformations at the lattice level under single-shot dynamic compression.

47 OTHER INSTRUMENTATION↗

Low cost solar array project production process and equipment task: A Module Experimental Process System Development Unit (MEPSDU)

Several major modifications were made to the design presented at the PDR. The frame was deleted in favor of a "frameless" design which will provide a substantially improved cell packing factor. Potential shaded cell damage resulting from operation into a short circuit can be eliminated by a change in the cell series/parallel electrical interconnect configuration. The baseline process sequence defined for the MEPSON was refined and equipment design and specification work was completed. SAMICS cost analysis work accelerated, format A's were prepared and computer simulations completed. Design work on the automated cell interconnect station was focused on bond technique selection experiments.

Source record↗

Time dependent three-dimensional body frame quantal wave packet treatment of the H + H2 exchange reaction on the Liu-Siegbahn-Truhlar-Horowitz (LSTH) surface

The first successful application of the three-dimensional quantum body frame wave packet approach to reactive scattering is reported for the H + H2 exchange reaction on the LSTH potential surface. The method used is based on a procedure for calculating total reaction probabilities from wave packets. It is found that converged, vibrationally resolved reactive probabilities can be calculated with a grid that is not much larger than required for the pure inelastic calculation. Tabular results are presented for several energies.

Neuhauser, Daniel↗

ISDN at NASA Lewis Research Center

An expository investigation of the potential impact of the Integrated Services Digital Network (ISDN) at NASA Lewis Research Center is described. To properly frame the subject, the paper contains a detailed survey of the components of Narrowband ISDN. The principles and objectives are presented as decreed by the Consultative Committee for International Telephone and Telegraph (CCITT). The various channel types are delineated and their associated service combinations are described. The subscriber-access network functions are explained pictorially via the ISDN reference configuration. A section on switching techniques is presented to enable the reader to understand the emergence of the concept of fast packet switching. This new technology is designed to operate over the high bandwidth, low error rate transmission media that characterizes the LeRC environment. A brief introduction to the next generation of networks is covered with sections on Broadband ISDM (B-ISDN), Asynchronous Transfer Mode (ATM), and Synchronous Optical Networks (SONET). Applications at LeRC are presented, first in terms of targets of opportunity, then in light of compatibility constraints. In-place pilot projects and testing are described that demonstrate actual usage at LeRC.

Bakes, Catherine Murphy↗

Far Term Noise Reduction Technology Roadmap for a Large Twin-Aisle Tube-And-Wing Subsonic Transport

Interest in unconventional aircraft architectures has steadily increased over the past several decades. However, each of these concepts has several technical challenges to overcome before maturing to the point of commercial acceptance. In the interim, it is important to identify any technologies that will enhance the noise reduction of conventional tube-and-wing aircraft. A technology roadmap with an assumed acoustic technology level of a 2035 entry into service is established for a large twin-aisle, tube-and-wing architecture to identify which technologies provide the most noise reduction. The noise reduction potential of the architecture relative to NASA noise goals is also assessed. The current roadmap estimates only a 30 EPNdB cumulative margin to Stage 4 for this configuration of a tube-and-wing aircraft with engines under the wing. This falls short of reaching even the 2025 Mid Term NASA goal (32 EPNdB) in the Far Term time frame. Specifically, the lack of additional technologies to reduce the aft fan noise and the corresponding installation effects is the key limitation of the noise reduction potential of the aircraft. Under the same acoustic technology assumptions, unconventional architectures are shown to offer an 8–10 EPNdB benefit from favorable relative placement of the engine when integrated to the airframe.

June, Jason C.↗

Civil Uses of Remotely Piloted Aircraft

The technology effort is identified and assessed that is required to bring the civil uses of RPVs to fruition and to determine whether or not the potential market is real and economically practical, the technologies are within reach, the operational problems are manageable, and the benefits are worth the cost. To do so, the economic, technical, and environmental implications are examined. The time frame is 1980-85. Representative uses are selected; detailed functional and performance requirements are derived for RPV systems; and conceptual system designs are devised. Total system cost comparisons are made with non-RPV alternatives. The potential market demand for RPV systems is estimated. Environmental and safety requirements are examined, and legal and regulatory concerns are identified. A potential demand for 2,000-11,000 RPV systems is estimated. Typical cost savings of 25-35% compared to non-RPV alternatives are determined. There appear to be no environmental problems, and the safety issue appears manageable.

Aderhold, J. R.↗

Description and User Instructions for the Quaternion_to_Orbit_v3 Software

For a given inertial frame of reference, the software combines the spacecraft orbits with the spacecraft attitude quaternions, and rotates the body-fixed reference frame of a particular spacecraft to the inertial reference frame. The conversion assumes that the two spacecraft are aligned with respect to the mutual line of sight, with a parameterized time tag. The software is implemented in Python and is completely open source. It is very versatile, and may be applied under various circumstances and for other related purposes. Based on the solid linear algebra analysis, it has an extra option for compensating the linear pitch. This software has been designed for simulation of the calibration maneuvers performed by the two spacecraft comprising the GRAIL mission to the Moon, but has potential use for other applications. In simulations of formation flights, one needs to coordinate the spacecraft orbits represented in an appropriate inertial reference frame and the spacecraft attitudes. The latter are usually given as the time series of quaternions rotating the body-fixed reference frame of a particular spacecraft to the inertial reference frame. It is often desirable to simulate the same maneuver for different segments of the orbit. It is also useful to study various maneuvers that could be performed at the same orbit segment. These two lines of study are more timeand labor-efficient if the attitude and orbit data are generated independently, so that the part of the data that has not been changed can be recycled in the course of multiple simulations.

Strekalov, Dmitry V.↗