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At least 217 records · Page 12

Bethanechol-Induced Water Intake in Rats: Possible Mechanisms of Induction

Acute administration of the parasympathomimetic agent, bethanechol, at 2, 4, 8 and 12 mg/kg body wt, IP, induced drinking and increased urine output of rats in a dose-dependent fashion. The first significant increases in both water intake and urine output above that of controls occurred when 4 mg/kg was administered. The drinking and increased urine output in response to administration of 8 mg bethanechol/kg was inhibited by atropine sulfate (3 and 6 mg/kg, IP). In addition, the 0-adrenergic antagonist, propranolol (6 mg/kg, IP, administered 30 min prior to treatment with bethanechol), inhibited bethanechol (8 mg/kg, IP)-induced drinking. Urine output, however, was unaffected by propranolol. Further, the angiotensin I converting enzyme inhibitor, captopril, inhibited significantly the drinking response, but not the increased urine output, accompanying administration of bethanechol (8 mg/kg). The effect of bethanechol and the beta-adrenergic agonist, isoproterenol (25 Ag/kg) separately and in combination, on water intake was also studied. Both compounds increased water intake but they exerted no interactive effect when administered simultaneously. Administration of bethanechol (8 mg/kg) to conscious rats was also accompanied by a significant reduction in both mean blood pressure and heart rate that reached minimal levels within 10 min after treatment. Both responses had returned to control level by one hour after treatment. These results suggest that bethanechol induces drinking in rats by way of the renin-angiotensin system.

Fregly, Melvin J.↗

Observations on CFD Verification and Validation from the AIAA Drag Prediction Workshops

The authors provide observations from the AIAA Drag Prediction Workshops that have spanned over a decade and from a recent validation experiment at NASA Langley. These workshops provide an assessment of the predictive capability of forces and moments, focused on drag, for transonic transports. It is very difficult to manage the consistency of results in a workshop setting to perform verification and validation at the scientific level, but it may be sufficient to assess it at the level of practice. Observations thus far: 1) due to simplifications in the workshop test cases, wind tunnel data are not necessarily the “correct” results that CFD should match, 2) an average of core CFD data are not necessarily a better estimate of the true solution as it is merely an average of other solutions and has many coupled sources of variation, 3) outlier solutions should be investigated and understood, and 4) the DPW series does not have the systematic build up and definition on both the computational and experimental side that is required for detailed verification and validation. Several observations regarding the importance of the grid, effects of physical modeling, benefits of open forums, and guidance for validation experiments are discussed. The increased variation in results when predicting regions of flow separation and increased variation due to interaction effects, e.g., fuselage and horizontal tail, point out the need for validation data sets for these important flow phenomena. Experiences with a recent validation experiment at NASA Langley are included to provide guidance on validation experiments.

Computational Fluid Dynamics↗

Effect of thrust vectoring and wing maneuver devices on transonic aeropropulsive characteristics of a supersonic fighter

The aeropropulsive characteristics of an advanced fighter designed for supersonic cruise were determined in the Langley 16-Foot Transonic Tunnel. The objectives of this investigation were to evaluate the interactive effects of thrust vectoring and wing maneuver devices on lift and drag and to determine trim characteristics. The wing maneuver devices consisted of a drooped leading edge and a trailing-edge flap. Thrust vectoring was accomplished with two dimensional (nonaxisymmetric) convergent-divergent nozzles located below the wing in two single-engine podded nacelles. A canard was utilized for trim. Thrust vector angles of 0 deg, 15 deg, and 30 deg were tested in combination with a drooped wing leading edge and with wing trailing-edge flap deflections up to 30 deg. This investigation was conducted at Mach numbers from 0.60 to 1.20, at angles of attack from 0 deg to 20 deg, and at nozzle pressure ratios from about 1 (jet off) to 10. Reynolds number based on mean aerodynamic chord varied from 9.24 x 10 to the 6th to 10.56 x 10 to the 6th.

Capone, F. J.↗

An analytical study of the effects of transverse shear deformation and anisotropy on buckling loads of laminated cylinders

Buckling loads of thick-walled orthotropic and anisotropic simply supported circular cylinders are predicted using a higher-order transverse-shear deformation theory. A comparison of buckling loads predicted by the conventional first-order transverse-shear deformation theory and the higher-order theory show that the additional allowance for transverse shear deformation has a negligible effect on the predicted buckling loads of medium-thick metallic isotropic cylinders. However, the higher-order theory predicts buckling loads which are significantly lower than those predicted by the first-order transverse-shear deformation theory for certain short, thick-walled cylinders which have low through-the-thickness shear moduli. A parametric study of the effects of ply orientation on the buckling load of axially compressed cylinders indicates that laminates containing 45 degree plies are most sensitive to transverse-shear deformation effects. Interaction curves for buckling loads of cylinders subjected to axial compressive and external pressure loadings indicate that buckling loads due to external pressure loadings are as sensitive to transverse-shear deformation effects as buckling loads due to axial compressive loadings. The effects of anisotropy are important over a much wider range of cylinder geometries than the effects of transverse shear deformation.

Jegley, Dawn C.↗

Compressor seal rub energetics study

The rub mechanics of compressor abradable blade tip seals at simulated engine conditions were investigated. Twelve statistically planned, instrumented rub tests were conducted with titanium blades and Feltmetal fibermetal rubstrips. The tests were conducted with single stationary blades rubbing against seal material bonded to rotating test disks. The instantaneous rub torque, speed, incursion rate and blade temperatures were continuously measured and recorded. Basic rub parameters (incursion rate, rub depth, abradable density, blade thickness and rub velocity) were varied to determine the effects on rub energy and heat split between the blade, rubstrip surface and rub debris. The test data was reduced, energies were determined and statistical analyses were completed to determine the primary and interactive effects. Wear surface morphology, profile measurements and metallographic analysis were used to determine wear, glazing, melting and material transfer. The rub energies for these tests were most significantly affected by the incursion rate while rub velocity and blade thickness were of secondary importance. The ratios of blade wear to seal wear were representative of those experienced in engine operation of these seal system materials.

Laverty, W. F.↗

Gender Differences in Isokinetic Strength after 60 and 90 d Bed Rest

Recent reports suggest that changes in muscle strength following disuse may differ between males and females. PURPOSE: To examine potential gender differences in strength changes following 60 and 90 d of experimental bed rest. METHODS: Isokinetic extensor and flexor strength of the knee (60deg and 180deg/s, concentric only), ankle (30deg/s, concentric and eccentric), and trunk (60deg/s, concentric only) were measured following 60 d (males: n=4, 34.5+/-9.6 y; females: n=4, 35.5+/-8.2 y) and 90 d (males: n=10, 31.4+/-4.8 y; females: n=5, 37.6+/-9.9 y) of 6-degree head-down-tilt bed rest (BR; N=23). Subjects were fed a controlled diet (55%/15%/ 30%, CHO/PRO/FAT) that maintained body weight within 3% of the weight recorded on Day 3 of bed rest. After a familiarization session, testing was conducted 6 d before BR and 2 d after BR completion. Peak torque and total work were calculated for the tests performed. To allow us to combine data from both 60- and 90-d subjects, we used a mixed-model statistical analysis in which time and gender were fixed effects and bed rest duration was a random effect. Log-transformations of strength measures were utilized when necessary in order to meet statistical assumptions. RESULTS: Main effects were seen for both time and gender (p<0.05), showing decreased strength in response to bed rest for both males and females, and males stronger than females for most strength measures. Only one interaction effect was observed: females exhibited a greater loss of trunk extensor peak torque at 60 d versus pre-BR, relative to males (p=0.004). CONCLUSION: Sixty and 90 d of BR induced significant losses in isokinetic muscle strength of the locomotor and postural muscles of the knee, ankle, and trunk. Although males were stronger than females for most of the strength measures that we examined, only changes in trunk extensor peak torque were greater for females than males at day 60 of bed rest

English, K. L.↗

Near-planar TS waves and longitudinal vortices in channel flow: Nonlinear interaction and focusing

The nonlinear interaction between planar or near-planar Tollmien-Schlichting waves and longitudinal vortices, induced or input, is considered theoretically for channel flows at high Reynolds numbers. Several kinds of nonlinear interaction, dependent on the input amplitudes and wavenumbers or on previously occurring interactions, are found and inter-related. The first, Type 1, is studied the most here and it usually produces spanwise focusing of both the wave and the vortex motion, within a finite scaled time, along with enhancement of both their amplitudes. This then points to the nonlinear interaction Type 2 where new interactive effects come into force to drive the wave and the vortex nonlinearly. Types 3, 4 correspond to still higher amplitudes, with 3 being related to 2, while 4 is connected with a larger-scale interaction 5 studied in an allied paper. Both 3, 4 are subsets of the full three-dimensional triple-deck-lie interaction, 6. The strongest nonlinear interactions are those of 4, 5, 6 since they alter the mean-flow profile substantially, i.e., by an 0(1) relative amount. All the types of nonlinear interaction however can result in the formation of focussed responses in the sense of spanwise concentrations and/or amplifications of vorticity and wave amplitude.

Hall, P.↗

Near-planar TS waves and longitudinal vortices in channel flow - Nonlinear interaction and focussing

The nonlinear interaction between planar or near-planar Tollmien-Schlichting waves and longitudinal vortices, induced or input, is considered theoretically for channel flows at high Reynolds numbers. Several kinds of nonlinear interaction, dependent on the input amplitudes and wavenumbers or on previously occurring interactions, are found and inter-related. The first, Type 1, is studied the most here and it usually produces spanwise focusing of both the wave and the vortex motion, within a finite scaled time, along with enhancement of both their amplitudes. This then points to the nonlinear interaction Type 2 where new interactive effects come into force to drive the wave and the vortex nonlinearly. Types 3, 4 correspond to still higher amplitudes, with 3 being related to 2, while 4 is connected with a larger-scale interaction 5 studied in an allied paper. Both 3, 4 are subsets of the full three-dimensional triple-deck-lie interaction, 6. The strongest nonlinear interactions are those of 4, 5, 6 since they alter the mean-flow profile substantially, i.e., by an O(1) relative amount. All the types of nonlinear interaction, however, can result in the formation of focused responses in the sense of spanwise concentrations and/or amplifications of vorticity and wave amplitude.

Hall, Philip↗

Cosmic ray sources, acceleration and propagation

A review is given of selected papers on the theory of cosmic ray (CR) propagation and acceleration. The high isotropy and a comparatively large age of galactic CR are explained by the effective interaction of relativistic particles with random and regular electromagnetic fields in interstellar medium. The kinetic theory of CR propagation in the Galaxy is formulated similarly to the elaborate theory of CR propagation in heliosphere. The substantial difference between these theories is explained by the necessity to take into account in some cases the collective effects due to a rather high density of relativisitc particles. In particular, the kinetic CR stream instability and the hydrodynamic Parker instability is studied. The interaction of relativistic particles with an ensemble of given weak random magnetic fields is calculated by perturbation theory. The theory of CR transfer is considered to be basically completed for this case. The main problem consists in poor information about the structure of the regular and the random galactic magnetic fields. An account is given of CR transfer in a turbulent medium.

Ptuskin, V. S.↗

Experimental and Numerical Investigation of Adsorption/Desorption in Packed Sorption Beds Under Ideal and Non-Ideal Flows

The importance of the wall effect on packed beds in the adsorption and desorption of carbon dioxide, nitrogen, and water on molecular sieve 5A of 0.127 cm in radius is examined experimentally and with one-dimensional computer simulations. Experimental results are presented for a 22.5-cm long by 4.5-cm diameter cylindrical column with concentration measurements taken at various radial locations. The set of partial differential equations are solved using finite differences and Newman's method. Comparison of test data with the axial-dispersed, non-isothermal, linear driving force model suggests that a two-dimensional model (submitted to Separation Science and Technology) is required for accurate simulation of the average column breakthrough concentration. Additional comparisons of test data with the model provided information on the interactive effects of carrier gas coadsorption with CO2, as well as CO2-H2O interactions.

Mohamadinejad, H.↗

STOL wind tunnel test results for a tactical supercruiser

Attention is given to the NASA Langley Research Center's testing of a 10.5 percent-scale supersonic cruiser (supercruiser) aircraft model in its V/STOL wind tunnel, in order to investigate the low speed aerodynamic characteristics of STOL enhancement devices. The STOL devices employed by the supercruiser configuration are high vector angle ramp nozzles, working in conjunction with a remote augmented lift system (RALS), in addition to a canard trim system. Also investigated were thrust reverser/ground plane interaction effects, for the evaluation of landing characteristics. It is noted that STOL approach thrust management requires the use of a partially reversing RALS nozzle which develops approximately 31 percent of main nozzle thrust, and that strong nose-up interactions during ground roll, with reverser operation, may limit dry power engine thrust for braking assistance to about 50 percent of maximum dry power.

Hutchison, R. A.↗

The effects of display-control I/O, compatibility, and integrality on dual-task performance and subjective workload

The utility of speech technology was evaluated in terms of three dual task principles: resource competition between the time shared tasks, stimulus central processing response compatibility, and task integrality. Empirical support for these principles was reviewed. Two studies investigating the interactive effects of the three principles were described. Objective performance and subjective workload ratings for both single and dual tasks were examined. It was found that the single task measures were not necessarily good predictors for the dual task measures. It was shown that all three principles played an important role in determining an optimal task configuration. This was reflected in both the performance measures and the subjective measures. Therefore, consideration of all three principles is required to insure proper use of speech technology in a complex environment.

Tsang, Pamela S.↗

CFD validation of subsonic turbulent planar shear layers

The primary objective of the present study is to assess the limitations and capabilities of RPLUS in predicting the entrainment, mixing, and burning characteristics of a high subsonic planar shear layer; these computations are performed in conjunction with an experiment being conducted at NASA Lewis Research Center. Turbulence is modeled by a two-equation k-epsilon closure modified for compressibility effects. Combustion is modeled by two different models: one in which a finite-rate laminar chemistry model is used for H2-O2 oxidation, and the other based on a composition joint pdf approach to account for the turbulence-chemistry interaction effects. Between upwind and centered differencing schemes, minimal differences are observed for the flow properties of a nonreacting shear layer case studied. In comparison with experimental data, computed growth rates are underpredicted in both reacting and nonreacting cases of a shear layer, but more severely for the reacting flows. However, the qualitative agreement between computation and experiment is reasonably good for the other observable characteristics, and indicative of potential for further improvements.

Lai, H. T.↗

Integrated Analysis Capability pilot computer program

An integrated analysis capability (IAC) computer software package was developed for the design analysis and performance evaluation of large space systems. The IAC aids the user in coupling the required technical disciplines (initially structures, thermal and controls), providing analysis solution paths which reveal critical interactive effects in order to study loads, stability and mission performance. Existing technical software modules, having a wide existing user community, are combined with the interface software to bridge between the different technologies and mathematical modeling techniques. The package is supported by executive, data management and interactive graphics software, with primary development within the superminicomputer environment.

Vos, R. G.↗

Nearfield Anisotropic Mesh Adaptation for the Third AIAA Sonic Boom Workshop

Sonic boom prediction is critical for the development of low-boom supersonic aircraft and encouraging a replacement of the overland commercial supersonic ban with a certification standard. The Third AIAA Sonic Boom Workshop nearfield test cases provide a unique opportunity to review anisotropic adaptive-mesh strategies for complex geometries with important propulsion interaction effects. Anisotropic metrics formulated to control estimated Mach interpolation and integrated nearfield pressure signature (goal-oriented) errors are compared with the results obtained on workshop-provided meshes. Detailed flow solutions and mesh renderings are combined with computational schlieren images to reveal the complex interactions present in a shock-plume interaction wind tunnel model and a prototype of the Low-Boom Flight Demonstrator. A favorable comparison of independent implementations of the entire simulation process provides evidence that each process is implemented correctly and sets a solid foundation for confidence in the nearfield prediction of each method.

sonic boom↗

Transition Analysis for the CRM-NLF Wind Tunnel Configuration

This paper presents the results of an ongoing study into the linear stability characteristics of the boundary layer flow over the common research model with natural laminar flow (CRMNLF) aircraft configuration. The flow conditions match selected test conditions from a recent wind tunnel experiment in the National Transonic Facility at the NASA Langley Research Center. Previous work involving parallel stability computations of a boundary layer flow based on the conical flow approximation has shown that the measured onset of laminar-turbulent transition during the experiments can be correlated with the linear amplification of Tollmien- Schlichting (TS) and stationary crossflow (CF) instabilities in the swept wing boundary layer. Here, we examine the effects of the simplifying approximations in both basic state computation and the stability analysis, with the goal of quantifying the resulting changes in the N-factor correlations. Specifically, the basic states are computed by using full Navier-Stokes equations and the stability analysis is performed by using a nonorthogonal coordinate system that allows a clear distinction between planar TS and CF instabilities. Furthermore, the effects of curvature and nonparallel mean flow have been included in the stability computations based on the parabolized stability equations (PSE). The fully turbulent Reynolds-Averaged-Navier-Stokes (RANS) mean flow solutions show good agreement with the measured wall pressure distribution. Viscous-inviscid interactive effects are observed to be important because the shock fronts along the suction surface are influenced by the imposed transition front. The stability results confirm the previous findings related to TS amplification within the inboard region of the wing and the dominance of stationary CF modes in the outboard region. However, given the close proximity of the measured transition front and the dual shock system within the outer part of the wing, the onset of transition may well be shock limited within the outboard region. In general, the transition criterion based on the dual N-factor method with N TS = N CF = 6 is reasonably successful at correlating with the measured transition fronts at Re MAC = 15 million and AoA = 1.5, 2 degrees; however, the low values of the correlating N-factors at Re MAC = 17.5 million support the hypothesis that the measured transition at the higher Reynolds number may have been strongly influenced by the merging of turbulent wedges that originate from surface imperfections near the leading edge.

Boundary layer transition↗

Transition Analysis for the CRM-NLF Wind Tunnel Configuration

This paper presents the results of an ongoing study into the linear stability characteristics of the boundary layer flow over the common research model with natural laminar flow (CRMNLF) aircraft configuration. The flow conditions match selected test conditions from a recent wind tunnel experiment in the National Transonic Facility at the NASA Langley Research Center. Previous work involving parallel stability computations of a boundary layer flow based on the conical flow approximation has shown that the measured onset of laminar-turbulent transition during the experiments can be correlated with the linear amplification of Tollmien- Schlichting (TS) and stationary crossflow (CF) instabilities in the swept wing boundary layer. Here, we examine the effects of the simplifying approximations in both basic state computation and the stability analysis, with the goal of quantifying the resulting changes in the N-factor correlations. Specifically, the basic states are computed by using full Navier-Stokes equations and the stability analysis is performed by using a nonorthogonal coordinate system that allows a clear distinction between planar TS and CF instabilities. Furthermore, the effects of curvature and nonparallel mean flow have been included in the stability computations based on the parabolized stability equations (PSE). The fully turbulent Reynolds-Averaged-Navier-Stokes (RANS) mean flow solutions show good agreement with the measured wall pressure distribution. Viscous-inviscid interactive effects are observed to be important because the shock fronts along the suction surface are influenced by the imposed transition front. The stability results confirm the previous findings related to TS amplification within the inboard region of the wing and the dominance of stationary CF modes in the outboard region. However, given the close proximity of the measured transition front and the dual shock system within the outer part of the wing, the onset of transition may well be shock limited within the outboard region. In general, the transition criterion based on the dual N-factor method with N TS = N CF = 6 is reasonably successful at correlating with the measured transition fronts at Re MAC = 15 million and AoA = 1.5, 2 degrees; however, the low values of the correlating N-factors at Re MAC = 17.5 million support the hypothesis that the measured transition at the higher Reynolds number may have been strongly influenced by the merging of turbulent wedges that originate from surface imperfections near the leading edge.

Boundary layer transition↗