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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 217 records · Page 12
All sourcesNASA NTRSDOE OSTI
NASA NTRS2014

Lightning Imaging Sensor (LIS) for the International Space Station (ISS): Mission Description and Science Goals

In recent years, NASA Marshall Space Flight Center, the University of Alabama in Huntsville, and their partners have developed and demonstrated space-based lightning observations as an effective remote sensing tool for Earth science research and applications. The Lightning Imaging Sensor (LIS) on the Tropical Rainfall Measuring Mission (TRMM) continues to provide global observations of total lightning after 17 years on-orbit. In April 2013, a space-qualified LIS built as the flight spare for TRMM, was selected for flight as a science mission on the International Space Station. The ISS LIS (or I-LIS as Hugh Christian prefers) will be flown as a hosted payload on the Department of Defense Space Test Program (STP) H5 mission, which has a January 2016 baseline launch date aboard a SpaceX launch vehicle for a 2-4 year or longer mission. The LIS measures the amount, rate, and radiant energy of global lightning. More specifically, it measures lightning during both day and night, with storm scale resolution, millisecond timing, and high, uniform detection efficiency, without any land-ocean bias. Lightning is a direct and most impressive response to intense atmospheric convection. It has been found that the characteristics of lightning that LIS measures can be quantitatively coupled to both thunderstorm and other geophysical processes. Therefore, the ISS LIS lightning observations will provide important gap-filling inputs to pressing Earth system science issues across a broad range of disciplines, including weather, climate, atmospheric chemistry, and lightning physics. A unique contribution from the ISS platform will be the availability of real-time lightning, especially valuable for operational applications over data sparse regions such as the oceans. The ISS platform will also uniquely enable LIS to provide simultaneous and complementary observations with other payloads such as the European Space Agency's Atmosphere-Space Interaction Monitor (ASIM) that will be exploring the connection between thunderstorms and lightning with terrestrial gamma-ray flashes (TGFs). Another important function of the ISS LIS will be to provide cross-sensor calibration/validation with a number of other payloads, including the TRMM LIS and the next generation geostationary lightning mappers (e.g., GOES-R Geostationary Lightning Mapper and Meteosat Third Generation Lightning Imager). This inter-calibration will improve the long term climate monitoring provided by all these systems. Finally, the ISS LIS will extend the time-series climate record of LIS lightning observations and expand the latitudinal coverage of LIS lightning to the climate significant upper middle-latitudes.

Blakeslee, R. J.↗
NASA NTRS1987

Interpreting the production of 26Al in Antarctic meteorites

Large numbers of meteorites have been concentrated at several locations in Antarctica. Glaciological mechanisms of grossly different time scales have been proposed to account for their transport by the ice, and the frequency distribution of the terrestrial ages of these objects has been suggested as a means of determining the relevant time scales. The upper limit to the ages of ice in Antarctica which would emerge from such a project is of interest to many other disciplines. After a meteorite reaches the Earth's surface, the specific radioactivity of Al-26 produced by cosmic rays while it was in space decreases because shielding by the Earth's atmosphere reduces further production to a neglible level. Thus, the known half life of this species can be used to determine the object's terrestrial age if the specific radioactivity at time of fall can be determined with reasonable accuracy and precision. The several models utilized for these predictions were based on the limited data available nearly two decades ago. The much larger data base now available was examined using multiple parameter regression analyses.

Heydegger, H. R.↗
DOE OSTI2021

Solving Inverse Stochastic Problems from Discrete Particle Observations Using the Fokker--Planck Equation and Physics-Informed Neural Networks

The Fokker--Planck (FP) equation governing the evolution of the probability density function (PDF) is applicable to many disciplines, but it requires specification of the coefficients for each case, which can be functions of space-time and not just constants and hence require the development of a data-driven modeling approach. When the data available is directly on the PDF, there exist methods for inverse problems that can be employed to infer the coefficients and thus determine the FP equation and subsequently obtain its solution. Herein, we address a more realistic scenario, where only sparse data are given on the particles' positions at a few time instants, which are not sufficient to accurately construct directly the PDF even at those times from existing methods, e.g., kernel estimation algorithms. To this end, we develop a general framework based on physics-informed neural networks (PINNs) that introduces a new loss function using the Kullback--Leibler divergence to connect the stochastic samples with the FP equation to simultaneously learn the equation and infer the multidimensional PDF at all times. In particular, we consider two types of inverse problems, type I, where the FP equation is known but the initial PDF is unknown, and type II, in which, in addition to the unknown initial PDF, the drift and diffusion terms are also unknown. In both cases, we investigate problems with either Brownian or Lévy noise or a combination of both. Here, we demonstrate the new PINN framework in detail in the one-dimensional (1D) case, but we also provide results for up to five dimensions demonstrating that we can infer both the FP equation and dynamics simultaneously at all times with high accuracy using only very few discrete observations of the particles.

97 MATHEMATICS AND COMPUTING↗
NASA NTRS1966

Progress in Development of Methods in Bone Densitometry

The effects of weightlessness and decreased activity on the astronaut's musculoskeletal system during prolonged space flight, missions are of concern to NASA. This problem was anticipated from the knowledge that human subjects lose significant quantities of calcium from the skeleton during periods of bedrest, immobilization, and water immersion. An accurate method of measurement of the changes in mineral content of the skeleton is required not only in the space program but also in the biological, medical, and dental fields for mineral metabolism studies and for studying various pathological conditions of the skeleton and teeth. This method is a difficult one requiring the coordinated efforts of physiologists, biophysicists, radiologists, and clinicians. The densitometry methods reported in this conference which have been used or are being developed include X-ray, beta excited X-rays, radioisotopes, sonic vibration, and neutron activation analysis Studies in the Gemini, Biosatellite, and Apollo flights use the X-ray bone densitometry method which requires making X-rays before and after the flights. An in-flight method of bone densitometry would be valuable, and use of radioisotope sources has been suggested. Many advances in bone densitometry have been made in the last five years, and the urgency of the requirement makes this working conference timely and valuable. In such a rapidly developing field with investigators working independently in a variety of scientific disciplines, a working conference is of great value in exchanging information and ideas, critically evaluating approaches and methods, and pointing out new research pathways.

DENSITOMETER↗
NASA NTRS2002

An Analysis for an Internet Grid to Support Space Based Operations

Currently, and in the past, dedicated communication circuits and "network services" with very stringent performance requirements have been used to support manned and unmanned mission critical ground operations at GSFC, JSC, MSFC, KSC and other NASA facilities. Because of the evolution of network technology, it is time to investigate other approaches to providing mission services for space ground and flight operations. In various scientific disciplines, effort is under way to develop network/komputing grids. These grids consisting of networks and computing equipment are enabling lower cost science. Specifically, earthquake research is headed in this direction. With a standard for network and computing interfaces using a grid, a researcher would not be required to develop and engineer NASA/DoD specific interfaces with the attendant increased cost. Use of the Internet Protocol (IP), CCSDS packet spec, and reed-solomon for satellite error correction etc. can be adopted/standardized to provide these interfaces. Generally most interfaces are developed at least to some degree end to end. This study would investigate the feasibility of using existing standards and protocols necessary to implement a SpaceOps Grid. New interface definitions or adoption/modification of existing ones for the various space operational services is required for voice both space based and ground, video, telemetry, commanding and planning may play a role to some undefined level. Security will be a separate focus in the study since security is such a large issue in using public networks. This SpaceOps Grid would be transparent to users. It would be anagulous to the Ethernet protocol's ease of use in that a researcher would plug in their experiment or instrument at one end and would be connected to the appropriate host or server without further intervention. Free flyers would be in this category as well. They would be launched and would transmit without any further intervention with the researcher or ground ops personnel. The payback in developing these new approaches in support of manned and unmanned operations is lower cost and will enable direct participation by more people in organizations and educational institutions in space based science. By lowering the high cost of space based operations and networking, more resource will be available to the science community for science. With a specific grid in place, experiment development and operations would be much less costly by using standardized network interfaces. Because of the extensive connectivity on a global basis, significant numbers of people would participate in science who otherwise would not be able to participate.

Bradford, Robert↗
NASA NTRS1987

Control of matric water potential by temperature differential

A method for controlling relative humidity based on temperature differentials, rather than on salt solutions, is described. This method has the following advantages: (1) it does not exhibit the anomalous CO2 solution effects that we have found to occur with salt solutions; (2) humidity is continuously adjustable without sample removal; (3) circulation of the atmosphere results in short equilibration times.

NASA Discipline Exobiology↗
NASA NTRS1993

Evolution in vitro: analysis of a lineage of ribozymes

Background: Catalytic RNAs, or ribozymes, possessing both a genotype and a phenotype, are ideal molecules for evolution experiments in vitro. A large, heterogeneous pool of RNAs can be subjected to multiple rounds of selection, amplification and mutation, leading to the development of variants that have some desired phenotype. Such experiments allow the investigator to correlate specific genetic changes with quantifiable alterations of the catalytic properties of the RNA. In addition, patterns of evolutionary change can be discerned through a detailed examination of the genotypic composition of the evolving RNA population. Results: Beginning with a pool of 10(13) variants of the Tetrahymena ribozyme, we carried out in vitro evolution experiments that led to the generation of ribozymes with the ability to cleave an RNA substrate in the presence of Ca2+ ions, an activity that does not exist for the wild-type molecule. Over the course of 12 generations, a seven-error variant emerged that has substantial Ca(2+)-dependent RNA-cleavage activity. Advantageous mutations increased in frequency in the population according to three distinct dynamics--logarithmic, linear and transient. Through a comparative analysis of 31 individual variants, we infer how certain mutations influence the catalytic properties of the ribozyme. Conclusions: In vitro evolution experiments make it possible to elucidate important aspects of both evolutionary biology and structural biochemistry on a reasonable short time scale.

Non-NASA Center↗
NASA NTRS1988

Preliminary report on radiocarbon dating of cryptoendolithic microorganisms

The existence of microbial communities living inside desert rocks has been reported by FRIEDMANN et al. (1967, 1976), first in rocks collected from the hot and dry Negev desert and later in rocks in the frigid Ross Desert of Southern Victoria Land, Antarctica. The extremely inhospitable climatic conditions in both places has led to the suggestion that these organisms have very low rates of metabolism and may, in addition, be very old (FRIEDMANN 1982). Our preliminary measurements showed a 14C deficiency indicating a carbon age in the order of magnitude of 10(3) years.

NASA Program Exobiology↗
NASA NTRS1990

Collagen in the spicule organic matrix of the gorgonian Leptogorgia virgulata

Decalcification of the calcareous spicules from the gorgonian Leptogorgia virgulata reveals an organic matrix that may be divided into water insoluble and soluble fractions. The insoluble fraction displays characteristics typical of collagen, which is an unusual component of an invertebrate calcium carbonate structure. This matrix fraction exhibits a collagenous amino acid profile and behavior upon SDS-PAGE. Furthermore, the reducible crosslink, dihydroxylysinonorleucine (DHLNL), is detected in this fraction. The composition of the matrix varies seasonally; i.e., the collagenous composition is most prevalent in the summer. These results indicate that the insoluble matrix is a dynamic structure. Potential roles of this matrix in spicule calcification are discussed.

Non-NASA Center↗
NASA NTRS1991

Pharmacokinetic consequences of spaceflight

Spaceflight induces a wide range of physiological and biochemical changes, including disruption of gastrointestinal (GI) function, fluid and electrolyte balance, circulatory dynamics, and organ blood flow, as well as hormonal and metabolic perturbations. Any of these changes can influence the pharmacokinetics and pharmacodynamics of in-flight medication. That spaceflight may alter bioavailability was proposed when drugs prescribed to alleviate space motion sickness (SMS) had little therapeutic effect. Characterization of the pharmacokinetic and/or pharmacodynamic behavior of operationally critical medications is crucial for their effective use in flight; as a first step, we sought to determine whether drugs administered in space actually reach the site of action at concentrations sufficient to elicit the therapeutic response.

NASA Center JSC↗
NASA NTRS1993

Hair cell regeneration in the bullfrog vestibular otolith organs following aminoglycoside toxicity

Adult bullfrog were given single intraotic injections of the aminoglycoside antibiotic gentamicin sulfate and sacrificed at postinjection times ranging from 0.5 to 9 days. The saccular and utricular maculae of normal and injected animals were examined in wholemount and cross-section. Intraotic 200 microM gentamicin concentrations resulted in the uniform destruction of the hair bundles and, at later times, the cell bodies of saccular hair cells. In the utriculus, striolar hair cells were selectively damaged while extrastriolar hair cells were relatively unaffected. Regenerating hair cells, identified in sectioned material by their small cell bodies and short, well-formed hair bundles, were seen in the saccular and utricular maculae as early as 24-48 h postinjection. Immature versions of mature hair cell types in both otolith organs were recognized by the presence or absence of a bulbed kinocilia and the relative lengths of their kinocilia and longest stereocilia. Utricular hair cell types with kinocilia longer than their longest stereocilia were observed at earlier than hair cell types with shorter kinocilia. In the sacculus, the hair bundles of gentamicin-treated animals, even at 9 days postinjection, were significantly smaller than those of normal animals. The hair bundles of utricular hair cells, on the other hand, reached full maturity within the same time period.

NASA Discipline Neuroscience↗
NASA NTRS2005

Measurement of hydraulic characteristics of porous media used to grow plants in microgravity

Understanding the effect of gravity on hydraulic properties of plant growth medium is essential for growing plants in space. The suitability of existing models to simulate hydraulic properties of porous medium is uncertain due to limited understanding of fundamental mechanisms controlling water and air transport in microgravity. The objective of this research was to characterize saturated and unsaturated hydraulic conductivity (K) of two particle-size distributions of baked ceramic aggregate using direct measurement techniques compatible with microgravity. Steady state (Method A) and instantaneous profile measurement (Method B) methods for K were used in a single experimental unit with horizontal flow through thin sections of porous medium providing an earth-based analog to microgravity. Comparison between methods was conducted using a crossover experimental design compatible with limited resources of space flight. Satiated (natural saturation) K ranged from 0.09 to 0.12 cm s-1 and 0.5 to >1 cm s-1 for 0.25- to 1- and 1- to 2-mm media, respectively. The K at the interaggregate/intraaggregate transition was approximately 10(-4) cm s-1 for both particle-size distributions. Significant differences in log(10)K due to method and porous medium were less than one order of magnitude and were attributed to variability in air entrapment. The van Genuchten/Mualem parametric models provided an adequate prediction of K of the interaggregate pore space, using residual water content for that pore space. The instantaneous profile method covers the range of water contents relevant to plant growth using fewer resources than Method A, all advantages for space flight where mass, volume, and astronaut time are limited.

NASA Center JSC↗
NASA NTRS2005

Large Scale Data Mining to Improve Usability of Data: An Intelligent Archive Testbed

Research in certain scientific disciplines - including Earth science, particle physics, and astrophysics - continually faces the challenge that the volume of data needed to perform valid scientific research can at times overwhelm even a sizable research community. The desire to improve utilization of this data gave rise to the Intelligent Archives project, which seeks to make data archives active participants in a knowledge building system capable of discovering events or patterns that represent new information or knowledge. Data mining can automatically discover patterns and events, but it is generally viewed as unsuited for large-scale use in disciplines like Earth science that routinely involve very high data volumes. Dozens of research projects have shown promising uses of data mining in Earth science, but all of these are based on experiments with data subsets of a few gigabytes or less, rather than the terabytes or petabytes typically encountered in operational systems. To bridge this gap, the Intelligent Archives project is establishing a testbed with the goal of demonstrating the use of data mining techniques in an operationally-relevant environment. This paper discusses the goals of the testbed and the design choices surrounding critical issues that arose during testbed implementation.

Ramapriyan, Hampapuram↗
NASA NTRS2002

Enhancement of preoxygenation for decompression sickness protection: effect of exercise duration

INTRODUCTION: Since strenuous exercise for 10 min during preoxygenation was shown to provide better protection from decompression sickness (DCS) incidence than resting preoxygenation, a logical question was: would a longer period of strenuous exercise improve protection even further? HYPOTHESIS: Increased strenuous exercise duration during preoxygenation increases DCS protection. METHODS: There were 60 subjects, 30 men and 30 women, who were exposed to 9,144 m (4.3 psia) for 4 h while performing mild, upper body exercise. Before the exposures, each subject performed three preoxygenation profiles on different days in balanced order: a 90-min resting preoxygenation control; a 240-min resting preoxygenation control; and a 90-min preoxygenation including exercise during the first 15 min. The subjects were monitored at altitude for venous gas emboli (VGE) with an echo-imaging system and observed for signs and symptoms of DCS. RESULTS: There were no significant differences in occurrence of DCS following any of the three preoxygenation procedures. Results were also comparable to an earlier report of 42% DCS with a 60-min preoxygenation including a 10-min exercise. There was no difference between VGE incidence in the comparison of protection offered by a 90-min preoxygenation with or without 13 min of strenuous exercise. The DCS incidence following a 240-min resting preoxygenation, 40%, was higher than observed during NASA studies and nearly identical with the earlier 42% DCS after a 60-min preoxygenation including exercise during the first 10 min. CONCLUSION: The protection offered by a 10 min exercise in a 60-min preoxygenation was not increased with extension of the preoxygenation exercise period to 15 min in a 90-min preoxygenation, indicating an upper time limit to the beneficial effects of strenuous exercise.

NASA Discipline Environmental Health↗
NASA NTRS1999

A procedure of multiple period searching in unequally spaced time-series with the Lomb-Scargle method

Periodogram analysis of unequally spaced time-series, as part of many biological rhythm investigations, is complicated. The mathematical framework is scattered over the literature, and the interpretation of results is often debatable. In this paper, we show that the Lomb-Scargle method is the appropriate tool for periodogram analysis of unequally spaced data. A unique procedure of multiple period searching is derived, facilitating the assessment of the various rhythms that may be present in a time-series. All relevant mathematical and statistical aspects are considered in detail, and much attention is given to the correct interpretation of results. The use of the procedure is illustrated by examples, and problems that may be encountered are discussed. It is argued that, when following the procedure of multiple period searching, we can even benefit from the unequal spacing of a time-series in biological rhythm research.

NASA Discipline Space Human Factors↗
NASA NTRS1999

Relative reactivity of ribosyl 2'-OH vs. 3'-OH in concentrated aqueous solutions of phosphoimidazolide activated nucleotides

Phosphoimidazolide activated ribomononucleotides (*pN, see structure) are useful substrates for the non-enzymatic synthesis of oligonucleotides. In the presence of metal ions, aqueous solutions of *pN yield primarily the two internucleotide-linked (pN2' pN and pN3' pN) and the pyrophosphate-linked (N5' ppN) dimers. Small amounts of cyclic dimers and higher oligomers are also produced. In this study the relative reactivity of 2'-OH vs. 3'-OH was determined from the ratio of the yields of pN2' pN vs. pN3' pN. Experiments were performed at 23 degrees C in the range 7.2 < or = pH < or = 8.4 with substrates that differ in nucleobase (guanosine (G), cytidine (C), uridine (U), and adenosine (A)) and leaving group (imidazole (Im), 2-methylimidazole (2-MeIm) and 2,4-dimethylimidazole (2,4-diMeIm)). Two metal ions (Mg2+ or Mn2+) were employed as catalysts. The conditions used here, i.e. a substrate concentration in the range 0.1 M to 1.0 M and metal ion concentration in the range 0.05 M to 0.2 M, favor base-stacking interactions. The ratio pN2' pN: pN3' pN = 2'-5': 3'-5' was found independent of nucleobase and typically varied between 2 to 3 indicating that the 2'-OH is about 2 to 3 times more reactive than the 3'-OH. *pN with Im, compared to 2-MeIm and 2,4-diMeIm leaving group, produce lower yields of internucleotide linked dimers, and a higher pN2' pN: pN3' pN ratio. Trends in the data, observed with all three leaving groups, suggest an increase in pN2' pN: pN3' pN ratio with decreasing substrate concentration (up to 5.47 with 0.051 M ImpG). The observations are in accord with earlier studies reporting a relative reactivity 2'-5': 3'-5' = 6 to 9 obtained with Im as the leaving group, in dilute nucleotide solutions and under conditions that disfavor stacking. It is speculated that the concentration induced change in the relative reactivity is the result of self-association via base-stacking that enhances selectively the proximity of the 3'-OH of one molecule to the reactive P-N bond of an other molecule. The implication of these conclusions for oligomerization/ligation reactions is discussed.

NASA Discipline Exobiology↗
NASA NTRS1987

Correlation between calmodulin activity and gravitropic sensitivity in primary roots of maize

Recent evidence indicates a role for calcium and calmodulin in the gravitropic response of primary roots of maize (Zea mays, L.). We examined this possibility by testing the relationship between calmodulin activity and gravitropic sensitivity in roots of the maize cultivars Merit and B73 x Missouri 17. Roots of the Merit cultivar require light to the gravitropically competent. The gravitropic response of the Missouri cultivar is independent of light. The occurrence of calmodulin in primary roots of these maize cultivars was tested by affinity gel chromatography followed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis with bovine brain calmodulin as standard. The distribution of calmodulin activity was measured using both the phosphodiesterase and NAD kinase assays for calmodulin. These assays were performed on whole tissue segments, crude extracts, and purified extracts. In light-grown seedlings of the Merit cultivar or in either dark- or light-grown seedlings of the Missouri cultivar, calmodulin activity per millimeter of root tissue was about 4-fold higher in the apical millimeter than in the subtending 3 millimeters. Calmodulin activity was very low in the apical millimeter of roots of dark-grown (gravitropically nonresponsive) seedlings of the Merit cultivar. Upon illumination, the calmodulin activity in the apical millimeter increased to a level comparable to that of light-grown seedlings and the roots became gravitropically competent. The time course of the development of gravitropic sensitivity following illumination paralleled the time course of the increase in calmodulin activity in the apical millimeter of the root. The results are consistent with the suggestion that calmodulin plays an important role in the gravitropic response of roots.

NASA Program Space Biology↗