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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 235 records · Page 13

Insulin-like growth factor I is required for the anabolic actions of parathyroid hormone on mouse bone

Parathyroid hormone (PTH) is a potent anabolic agent for bone, but the mechanism(s) by which it works remains imperfectly understood. Previous studies have indicated that PTH stimulates insulin-like growth factor (IGF) I production, but it remains uncertain whether IGF-I mediates some or all of the skeletal actions of PTH. To address this question, we examined the skeletal response to PTH in IGF-I-deficient (knockout [k/o]) mice. These mice and their normal littermates (NLMs) were given daily injections of PTH (80 microg/kg) or vehicle for 2 weeks after which their tibias were examined for fat-free weight (FFW), bone mineral content, bone structure, and bone formation rate (BFR), and their femurs were assessed for mRNA levels of osteoblast differentiation markers. In wild-type mice, PTH increased FFW, periosteal BFR, and cortical thickness (C.Th) of the proximal tibia while reducing trabecular bone volume (BV); these responses were not seen in the k/o mice. The k/o mice had normal mRNA levels of the PTH receptor and increased mRNA levels of the IGF-I receptor but markedly reduced basal mRNA levels of the osteoblast markers. Surprisingly, these mRNAs in the k/o bones increased several-fold more in response to PTH than the mRNAs in the bones from their wild-type littermates. These results indicate that IGF-I is required for the anabolic actions of PTH on bone formation, but the defect lies distal to the initial response of the osteoblast to PTH.

Non-NASA Center↗

Introduction to special section: early Mars

Ongoing studies of the evolution of the Martian cratered highlands, the nature of the planet's early climate, and the recent announcement of possible evidence of ancient life in the ALH 84001 meteorite have reinvigorated interest in the conditions that prevailed on Mars during its first billion years of geologic history. To address this interest and assess our current understanding of these issues, the Lunar and Planetary Institute hosted a 4-day Conference on Early Mars in Houston in April of 1997. The papers contained in this special section are a product of that meeting. The purpose of the conference was twofold: (1) to consider how impacts, volcanism, and the presence of abundant water affected the physical and chemical environment that existed on Mars 4 Gyr ago, particularly as it related to the nature of the global climate, the origin of the valley networks, the geologic and mineralogic evolution of the surface, the aqueous geochemistry of groundwater, and the existence of local environments that may have been conducive to the development of indigenous life and the preservation of its signature in the geologic record; and (2) to discuss what observations or experiments might he included in future spacecraft missions to test the ideas and expectations arising from purpose 1. While pertinent issues of early atmospheric and solar evolution were also addressed, the primary discussion at the conference focused on the evidence and constraints provided by the geologic records of Earth, the Moon, and Mars and analysis of the SNC meteorites. The papers contained in this special section span the full range of these topics, including the stability of the early atmosphere to erosion by the solar wind, the geologic environment from which the SNC meteorites originated, geomorphic evidence regarding the nature of the early Martian climate and hydrologic cycle, the potential impact of the past and present environment on the preserved signature of ancient life, and a discussion of the capabilities of a lander-based X ray diffraction and fluorescence instrument to assess the potential for past fossilization from the mineralogy of the current local surface environment. The issues raised at the conference, and by the papers included in this special section, will be the focus of ongoing attention as the intensity and scope of Mars exploration increases over the next decade.

NASA Center ARC↗

Effect of environmental enrichment devices on behaviors of single- and group-housed squirrel monkeys (Saimiri sciureus)

Squirrel monkeys display an interest in novel places, habituate to new situations, and spend most of their daily activity in the wild in large groups engaging in feeding behaviors over a broad area. Captivity limits these behaviors and consequently may disrupt normal social organizations. In captivity, squirrel monkeys may exhibit stereotypical behaviors that are believed to indicate decreased psychologic well-being. When a monkey's behavior can be made to approach that seen in the wild, and stereotypical behaviors are minimal, it is assumed that psychologic well-being is adequate. Environmental enrichment devices have been used to address the Animal Welfare Act requirement that psychologic well-being of captive nonhuman primates be considered. The purpose of the study reported here was to examine whether various environmental enrichment devices improve the psychologic well-being of captive squirrel monkeys. In the study, we used behavioral observation to quantify the effectiveness of several environmental enrichment devices for reducing stereotypical behaviors in squirrel monkeys housed alone or in groups. Analysis of our results revealed that the environmental enrichment devices did not affect the expression of normal or stereotypical behaviors, but that the type of housing did.

NASA Discipline Neuroscience↗

Design, Development, and Maintenance of the GLOBE Program Website and Database

This is a 1-year (Fy 03) proposal to design and develop enhancements, implement improved efficiency and reliability, and provide responsive maintenance for the operational GLOBE (Global Learning and Observations to Benefit the Environment) Program website and database. This proposal is renewable, with a 5% annual inflation factor providing an approximate cost for the out years.

Brummer, Renate↗

Parametric Testing of Chevrons on Single Flow Hot Jets

A parametric family of chevron nozzles have been studied, looking for relationships between chevron geometric parameters, flow characteristics, and far-field noise. Both cold and hot conditions have been run at acoustic Mach number 0.9. Ten models have been tested, varying chevron count, penetration, length, and chevron symmetry. Four comparative studies were defined from these datasets which show: that chevron length is not a major impact on either flow or sound; that chevron penetration increases noise at high frequency and lowers it at low frequency, especially for low chevron counts; that chevron count is a strong player with good low frequency reductions being achieved with high chevron count without strong high frequency penalty; and that chevron asymmetry slightly reduces the impact of the chevron. Finally, it is shown that although the hot jets differ systematically from the cold one, the overall trends with chevron parameters is the same.

Bridges, James↗

Flow Visualization at Cryogenic Conditions Using a Modified Pressure Sensitive Paint Approach

A modification to the Pressure Sensitive Paint (PSP) method was used to visualize streamlines on a Blended Wing Body (BWB) model at full-scale flight Reynolds numbers. In order to achieve these conditions, the tests were carried out in the National Transonic Facility operating under cryogenic conditions in a nitrogen environment. Oxygen is required for conventional PSP measurements, and several tests have been successfully completed in nitrogen environments by injecting small amounts (typically < 3000 ppm) of oxygen into the flow. A similar technique was employed here, except that air was purged through pressure tap orifices already existent on the model surface, resulting in changes in the PSP wherever oxygen was present. The results agree quite well with predicted results obtained through computational fluid dynamics analysis (CFD), which show this to be a viable technique for visualizing flows without resorting to more invasive procedures such as oil flow or minitufts.

Watkins, A. Neal↗

Control of gravitropic orientation. II. Dual receptor model for gravitropism

Gravitropism of vascular plants has been assumed to require a single gravity receptor mechanism. However, based on the evidence in Part I of this study, we propose that maize roots require two. The first mechanism is without a directional effect and, by itself, cannot give rise to tropism. Its role is quantitative facilitation of the second mechanism, which is directional like the gravitational force itself and provides the impetus for tropic curvature. How closely coupled the two mechanisms may be is, as yet, unclear. The evidence for dual receptors supports a general model for roots. When readiness for gravifacilitation, or gravifacilitation itself, is constitutive, orthogravitropic curvature can go to completion. If not constitutively enabled, gravifacilitation can be weak in the absence of light and water deficit or strong in the presence of light and water deficit. In either case, it can decay and permit roots to assume reproducible non-vertical orientations (plagiogravitropic or plagiotropic orientations) without using non-vertical setpoints. In this way roots are deployed in a large volume of soil. Gravitropic behaviours in shoots are more diverse than in roots, utilising oblique and horizontal as well as vertical setpoints. As a guide to future experiments, we assess how constitutive v. non-constitutive modes of gravifacilitation might contribute to behaviours based on each kind of setpoint.

NASA Discipline Plant Biology↗

Control of gravitropic orientation. I. Non-vertical orientation by primary roots of maize results from decay of competence for orthogravitropic induction

Plant organs may respond to gravity by vertical (orthogravitropic), oblique (plagiogravitropic) or horizontal (diagravitropic) growth. Primary roots of maize (Zea mays L.) provide a good system for studying such behaviours because they are reportedly capable of displaying all three responses. In current work using maize seedlings of the Silver Queen cultivar, stabilisation of growth at an oblique orientation was commonplace. Hypothetically, plagiogravitropism may be accomplished either by a process we call graded orthogravitropism or by hunting about a sensed non-vertical setpoint. In graded orthotropism primary bending is unidirectional and depends on facilitative stimuli that determine its extent. The hallmark of the setpoint mechanism is restorative curvature of either sign following a displacement; both diagravitropism and orthogravitropism are based on setpoints. Roots settled in a plagiogravitropic orientation were tested with various illumination and displacement protocols designed to distinguish between these two hypotheses. The tests refuted the setpoint hypothesis and supported that of graded orthotropism. No evidence of diagravitropism could be found, thus, earlier claims were likely based on inadequately controlled observations of graded orthotropism. We propose that orthotropism is graded by the sequential action of dual gravity receptors: induction of a vectorial gravitropic response requires gravitational induction of a separate facilitative response, whose decay in the absence of fresh stimuli can brake gravitropism at plagiotropic angles.

NASA Discipline Plant Biology↗

Validation of the Small Hot Jet Acoustic Rig for Jet Noise Research

The development and acoustic validation of the Small Hot Jet Aeroacoustic Rig (SHJAR) is documented. Originally conceived to support fundamental research in jet noise, the rig has been designed and developed using the best practices of the industry. While validating the rig for acoustic work, a method of characterizing all extraneous rig noise was developed. With this in hand, the researcher can know when the jet data being measured is being contaminated and design the experiment around this limitation. Also considered is the question of uncertainty, where it is shown that there is a fundamental uncertainty of 0.5dB or so to the best experiments, confirmed by repeatability studies. One area not generally accounted for in the uncertainty analysis is the variation which can result from differences in initial condition of the nozzle shear layer. This initial condition was modified and the differences in both flow and sound were documented. The bottom line is that extreme caution must be applied when working on small jet rigs, but that highly accurate results can be made independent of scale.

Bridges, James↗

Space-Based Gravitational-Wave Observations as Tools for Testing General Relativity

We continued a project, to analyse the ways in which detection and study of gravitational waves could provide quantitative tests of general relativity, with particular emphasis on waves that would be detectable by space-based observatories, such as LISA. This work had three foci: 1) Tests of scalar-tensor theories of gravity that, could be done by analyzing gravitational waves from neutron stars inspiralling into massive black holes, as detectable by LISA; 2) Study of alternative theories of gravity in which the graviton could be massive, and of how gravitational-wave observations by space-based detectors, solar-system tests, and cosmological observations could constrain such theories; and 3) Study of gravitational-radiation back reaction of particles orbiting black holes in general relativity, with emphasis on the effects of spin.

Will, Clifford M.↗

Modular Avionics Concept Developed for Microgravity Space Experiments: FEANICS

The Flow Enclosure Accommodating Novel Investigations in Combustion of Solids (FEANICS) is a facility being developed at the NASA Glenn Research Center that will be integrated into the Combustion Integrated Rack onboard the International Space Station. FEANICS will support various experimental studies of solid combustion in a microgravity environment. The experiments will vary, and the FEANICS facility hardware combined with the Combustion Integrated Rack hardware is designed to meet the science requirements of the individual experiments.

Hausmann, Clifford R.↗

Mars chronology: assessing techniques for quantifying surficial processes

Currently, the absolute chronology of Martian rocks, deposits and events is based mainly on crater counting and remains highly imprecise with epoch boundary uncertainties in excess of 2 billion years. Answers to key questions concerning the comparative origin and evolution of Mars and Earth will not be forthcoming without a rigid Martian chronology, enabling the construction of a time scale comparable to Earth's. Priorities for exploration include calibration of the cratering rate, dating major volcanic and fluvial events and establishing chronology of the polar layered deposits. If extinct andor extant life is discovered, the chronology of the biosphere will be of paramount importance. Many radiometric and cosmogenic techniques applicable on Earth and the Moon will apply to Mars after certain baselines (e.g. composition of the atmosphere, trace species, chemical and physical characteristics of Martian dust) are established. The high radiation regime may pose a problem for dosimetry-based techniques (e.g. luminescence). The unique isotopic composition of nitrogen in the Martian atmosphere may permit a Mars-specific chronometer for tracing the time-evolution of the atmosphere and of lithic phases with trapped atmospheric gases. Other Mars-specific chronometers include measurement of gas fluxes and accumulation of platinum group elements (PGE) in the regolith. Putting collected samples into geologic context is deemed essential, as is using multiple techniques on multiple samples. If in situ measurements are restricted to a single technique it must be shown to give consistent results on multiple samples, but in all cases, using two or more techniques (e.g. on the same lander) will reduce error. While there is no question that returned samples will yield the best ages, in situ techniques have the potential to be flown on multiple missions providing a larger data set and broader context in which to place the more accurate dates.

Doran, Peter T.↗

Terrestrial analogs to Mars

It is well recognized that interpretations of Mars must begin with the Earth as a reference. The most successful comparisons have focused on understanding geologic processes on the Earth well enough to extrapolate to Mars' environment. Several facets of terrestrial analog studies have been pursued and are continuing.

Mars↗

Wild2 approach maneuver strategy used for Stardust spacecraft (extended abstract)

Stardust, NASA's first dedicated sample return mission to a comet, successfully flew through the comet dust around Wold2 on January 2, 2004. The spacecraft flew within 236 km of the comet, meeting the mission requirement of 250+/- 50 km on flyby distance. Stardust collected dust particles and took several images of the comet while flying close to Wild2. The spacecraft will return to earth with the comet samples on January 15, 2006. To accomplish the above objective, a large Deep Space Maneuver (DSM#) was implemented during June 17 and 18, 2003 and a series of Trajectory Correction Maneuvers (TCMs) were also implemented during the 30 days prior to encounter. Both maneuver design and executions were influenced by number of factors including the small body ephemeris uncertainty, predictability of small forces arising from 3-axis attitude limit cycling and spacecraft slews. Maneuver design processes, including contingency plans, and maneuver performance characteristics, are discussed in this paper.

dust↗

Acoustic Efficiency of Azimuthal Modes in Jet Noise Using Chevron Nozzles

The link between azimuthal modes in jet turbulence and in the acoustic sound field has been examined in cold, round jets. Chevron nozzles, however, impart an azimuthal structure on the jet with a shape dependent on the number, length and penetration angle of the chevrons. Two particular chevron nozzles, with 3 and 4 primary chevrons respectively, and a round baseline nozzle are compared at both cold and hot jet conditions to determine how chevrons impact the modal structure of the flow and how that change relates to the sound field. The results show that, although the chevrons have a large impact on the azimuthal shape of the mean axial velocity, the impact of chevrons on the azimuthal structure of the fluctuating axial velocity is small at the cold jet condition and smaller still at the hot jet condition. This is supported by results in the azimuthal structure of the sound field, which also shows little difference in between the two chevron nozzles and the baseline nozzle in the distribution of energy across the azimuthal modes measured.

Brown, Clifford A.↗

Review of Cranked-Arrow Wing Aerodynamics Project: Its International Aeronautical Community Role

This paper provides a brief history of the F-16XL-1 aircraft, its role in the High Speed Research (HSR) program and how it was morphed into the Cranked Arrow Wing Aerodynamics Project (CAWAP). Various flight, wind-tunnel and Computational Fluid Dynamics (CFD) data sets were generated during the CAWAP. These unique and open flight datasets for surface pressures, boundary-layer profiles and skinfriction distributions, along with surface flow data, are described and sample data comparisons given. This is followed by a description of how the project became internationalized to be known as Cranked Arrow Wing Aerodynamics Project International (CAWAPI) and is concluded by an introduction to the results of a 4 year CFD predictive study of data collected at flight conditions by participating researchers.

Lamar, John E.↗

SpaceWire Plug and Play

The ability to rapidly deploy inexpensive satellites to meet tactical goals has become an important goal for military space systems. In fact, Operationally Responsive Space (ORS) has been in the spotlight at the highest levels. The Office of the Secretary of Defense (OSD) has identified that the critical next step is developing the bus standards and modular interfaces. Historically, satellite components have been constructed based on bus standards and standardized interfaces. However, this has not been done to a degree, which would allow the rapid deployment of a satellite. Advancements in plug-and-play (PnP) technologies for terrestrial applications can serve as a baseline model for a PnP approach for satellite applications. Since SpaceWire (SpW) has become a de facto standard for satellite high-speed (greater than 200Mbp) on-board communications, it has become important for SpW to adapt to this Plug and Play (PnP) environment. Because SpW is simply a bulk transport protocol and lacks built-in PnP features, several changes are required to facilitate PnP with SpW. The first is for Host(s) to figure out what the network looks like, i.e., how pieces of the network, routers and nodes, are connected together; network mapping, and to receive notice of changes to the network. The second is for the components connected to the network to be understood so that they can communicate. The first element, network topology mapping & change of status indication, is being defined (topic of this paper). The second element describing how components are to communicate has been defined by ARFL with the electronic data sheets known as XTEDS. The first element, network mapping, is recent activities performed by Air Force Research Lab (ARFL), Naval Research Lab (NRL), NASA and US industry (Honeywell, Clearwater, FL, and others). This work has resulted in the development of a protocol that will perform the lower level functions of network mapping and Change Of Status (COS) indication required by Plug 'n' Play over SpaceWire. This work will be presented to the SpaceWire working group for standardization under European Cooperation for Space Standardization (ECSS) and to obtain a permanent Protocol ID (see SpaceWire Protocol ID: What Does it Mean to You; IEEE Aerospace Conference 2006). The portion of the Plug 'n' Play protocol that will be described in this paper is how the Host(s) of a SpaceWire network map the network and detect additions and deletions of devices on a SpaceWire network.

Rakow, Glenn↗