The relationship of nocturnal headaches to sleep stage patterns
Nocturnal headache relationship to REM sleep stage from EEG, EOG and EMG data
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Nocturnal headache relationship to REM sleep stage from EEG, EOG and EMG data
Stability of sleep patterns in young adults for sequential nights over three week period
Development of apparatus and method for quantitatively measuring brain activity as automatic indication of sleep state and level of consciousness
Prototype device for monitoring sleep during manned space flight including performance tests
Comparison of human sleep disturbance in three age groups by subsonic jet aircraft noise and simulated sonic booms
Automatic real-time scoring of simultaneous sleep electroencephalograms
Neuron pairs discharge sequence temporal correlation in cats association cortex during natural sleep and wakefulness
Biosatellite 3 monkey sleep and wake states based on visual and computer analysis of telemetered EEG data from earth orbital flight
Subcortical-cortical EEG recording of unrestrained chimpanzees sleep cycles, using computer analysis and biotelemetry techniques
Simulated sonic booms and subsonic jet aircraft noise effects on human subjects of various ages during different sleep stages
First and last rapid eye movement /REM/ sleep differences in unrestrained chimpanzee
The feasibility of recording the electroencephalogram during space flight is demonstrated. The precise information that is collected with the electroencephalograph regarding the duration, depth, and number of sleep periods implies that electroencephalogram monitoring should be considered for routine use in the long-duration space flights that are contemplated for the Apollo Program and other programs. The importance of such information in the direction and execution of the flight, both to the medical monitors and to the crewmembers, is obvious.
The research describes the sleep disturbing effects of jet aircraft flyover noise as it occurs at different times during the night. The results indicate that individuals respond statistically more, in terms of greater cortical desynchronization, during the first and last thirds of the night. During the middle third, while there is still a significant amount of cortical desynchronization in response to the jet aircraft noise, this is always less than that which occurs earlier or later in the night. The implications of this data are that it might be possible to reduce the disruptive effects of at least certain extrinsic sonic stimulation by appropriate scheduling.
The electroencephalographic and behavioral responses during sleep of eight women subjects, aged 29 to 49 years, to subsonic jet flyover noise and simulated sonic booms were tested over 14 consecutive nights. Stimulus intensities were 101, 113, and 119 PNdB (as if measured out-of-doors) for the subsonic jet flyover and 0.67, 2.50, and 5.0 psf (as if measured out-of-doors) for the simulated sonic booms. It was found that the women were awakened, on the average, by approximately 42 percent of the flyover noises and by approximately 15 percent of the simulated sonic booms. Comparison of the results of this study with those of a similar study using men as subjects revealed that women were awakened more frequently by the subsonic jet flyover noise then were the men, while men were awakened more frequently by the simulated sonic boom.
A computer-analysis technique was used to evaluate the changes in the waking EEGs of 5 normal subjects which occurred during the oral administration of flurazepam hydrochloride (Dalmane). While the subjects were receiving the drug, there was an increase in the amount of beta (14-38 c/sec) activity in fronto-central EEG leads in all 5 subjects. This increase in beta activity was characterized by a highly consistent increase in the number of waves that occurred during an EEG recording interval of fixed duration and by a less consistent increase in average wave amplitude. There was no detectable change in mean EEG wavelength (frequency) within the beta frequency range. The EEG patterns reverted to their baseline condition during 2-3 weeks after withdrawal of the drug. Analysis of the alpha, theta and delta components of the EEG indicated no changes during or following administration of the drug. This study clearly illustrates the usefulness of specific computer-analysis techniques in the characterization and quantification of sleep-promoting drugs upon the EEG of the normal young adults in the waking state. Two preamplifiers and 150 EEG monitoring caps with electrodes were delivered to MSC.
Under controlled conditions in two test rooms, studies were made of the response of sleeping subjects to the stimuli of simulated sonic booms and subsonic jet aircraft noise. Children were relatively nonresponsive to the stimuli. In general, the older the subject, the more likely is behavioral awakening. The response rates to the two types of stimuli were essentially the same. The stimulus intensity had little, if any, effect on frequency of arousal, although other degrees of response did increase.
Responses, both overt behavior and those measured by electroencephalograph, to noise by eight male subjects were studied for sixteen consecutive nights. Test stimuli were: (1) The simulated sideline noise of a short takeoff and landing aircraft with blown flaps; (2) the simulated sideline noise of a STOL aircraft of turbofan design; (3) the simulated takeoff noise of the blown flap STOL aircraft; and (4) a four second burst of simulated pink noise. Responses to each noise were tested at three noise intensities selected to represent levels expected indoors from operational aircraft. The results indicate that the blown flap STOL aircraft noise resulted in 8 to 10 percent fewer sleep disturbance responses than did the turbofan STOL aircraft when noises of comparable intensities from similar maneuvers were used.
The effects of various hypnotics on sleep stage parameters and on the parameters of effectiveness were evaluated along with the effects of several commonly used yet distinctly different hypnotics on daytime performance. The effects on daytime performance of two nonhypnotics commonly used in the space program were also examined.