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Radiation Stability Evaluation of Protein-Based Nanopores for Mars and Europa Missions

Exploration of our Solar System has revealed a number of locations that are now habitable or could have supported life in the past. One approach to finding life involves detection of informational polymers like deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) that are definitive biosignatures for life as we know it. Alternatively, structural variants of DNA and RNA, collectively termed xenonucleic acids (XNAs) have been shown in the laboratory to behave similarly. Nanopore-based sequencers differ from traditional sequencing technologies in that they do not explicitly require synthesis of DNA before or during analysis. Because of this, nanopore sequencers have been used for the direct sequencing of RNA, and could be used for the detection and analysis of other charged polymers. Here we describe results of exposing the MinION hardware, flow cells, and key reagents to ionizing radiation at doses relevant to Mars and Europa missions (10 to 3000 silicon-equivalent gray).

Burton, Aaron S.↗

The Maturing of High Contrast Imaging and Starlight Suppression Techniques for Future NASA Exoplanet Characterization Missions

Over 3000 exoplanets and hundreds of exoplanetary systems have been detected to date and we are now rapidly moving toward an era where the focus is shifting from detection to direct imaging and spectroscopic characterization of these new worlds and their atmospheres. NASA is currently studying several exoplanet characterization mission concepts for the 2020 Decadal Survey ranging from probe class to flagships. Detailed and comprehensive exoplanet characterization, particularly of exo-Earths, leading to assessment of habitability, or indeed detection of life, will require significant advances beyond the current state-of-the-art in high contrast imaging and starlight suppression techniques which utilize specially shaped precision optical elements to block the light from the parent star while controlling scattering and diffraction thus revealing and enabling spectroscopic study of the orbiting exoplanets in reflected light. In this paper we describe the two primary high contrast starlight suppression techniques currently being pursued by NASA: 1) coronagraphs (including several design variations) and 2) free-flying starshades. These techniques are rapidly moving from the technology development phase to the design and engineering phase and we discuss the prospects and projected performance for future exoplanet characterization missions utilizing these techniques coupled with large aperture telescopes in space.

high contrast↗

The Search for Chiral Asymmetry as a Potential Biosignature in Samples from Mars

The search for evidence of extraterrestrial life in our solar system is currently guided by our understanding of terrestrial biology and its associated biosignatures. The observed homochirality in all life on Earth, that is, the predominance of “left-handed” or L-amino acids and “right-handed” or D-sugars, is a unique property of life that is crucial for molecular recognition, enzymatic function, information storage and structure and is thought to be a prerequisite for the origin or early evolution of life. Therefore, the detection of L- or D-enantiomeric excesses of chiral amino acids and sugars could be a powerful indicator of extant or extinct life on Mars or other habitable environments in our solar system. The exploration of habitable environments on Mars, including an assessment of the preservation potential for complex organics of either abiotic or biological origin, remains a key goal of both current and future Mars missions. Now with the unambiguous detection of indigenous organic matter in sedimentary rocks on Mars [1-3], NASA’s Curiosity rover has significantly advanced our understanding of the preservation of potential chemical biosignatures in the martian near surface. Although amino acids have not yet been identified by in situ measurements on Mars, if they were present, it is expected that amino acid hydrolysis and racemization would be very slow and any chiral or isotopic signatures from an extinct martian biota could be preserved for billions of years, given the extremely cold and dry surface conditions [4]. One of ESA’s Rosalind Franklin rover payload instruments called the Mars Organic Molecule Analyzer (MOMA) includes a wet chemistry package capable of measuring the enantiomeric ratios of any chiral amino acids present at part-per-million concentrations or higher [5]. The complexity and limited duration of spaceflight operations and the known analytical challenges associated with in situ extraction and characterization of trace reduced organic compounds in ancient rocks make it challenging to determine the origins of martian organic matter found to date. Coordinated state-of-the-art laboratory measurements of returned samples from Mars that include spatially resolved chemical, mineralogical, and isotopic studies and molecule-specific isotopic and enantiomeric measurements will be required to firmly establish whether the complex organic matter detected on Mars comes from biotic or abiotic sources. Ultimately, sample return may be our best chance of identifying chemical biosignatures from a past or present martian biota, if one ever existed on Mars. NASA’s Perseverance rover will collect dozens of surface sample cores for possible future return to Earth by NASA and ESA. Here we review our current knowledge of the distributions and enantiomeric and isotopic compositions of non-biological amino acids found in meteorites compared to terrestrial biochemistry and propose a set of measurement criteria that should be used to help establish the origin of any chiral asymmetry detected in samples from Mars [6].

Daniel P Glavin↗

The Search for Chiral Asymmetry as a Potential Biosignature in Samples from Mars

The search for evidence of extraterrestrial life in our solar system has been guided by our under-standing of terrestrial biology and its associated biosignatures. The observed homochirality in all life on Earth, that is, the predominance of “left-handed” or L-amino acids and “right-handed” or D-sugars, is a unique property of life that is crucial for molecular recognition, enzymatic function, information storage and structure, and is thought to be a prerequisite for the origin or early evolution of life. Therefore, the detection of L- or D-excesses of chiral amino acids or sugars could be a powerful indicator of extant or extinct life on Mars or other habitable environments in our solar system. However, studies of primitive meteorites have revealed that they contain extraterrestrial amino acids and sugar acids with large enantiomeric excesses (60% and higher) that resulted from non-biological processes [1], complicating the use of chiral asymmetry by itself as a definitive biosignature. The exploration of habitable environments on Mars, including an assessment of the preservation potential for complex organics of either abiotic or biological origin, is an objective of both current and future Mars missions. Now with the unambiguous detection of indigenous organic matter in sedimentary rocks by the Sample Analysis at Mars (SAM) instrument suite on Mars [2-5], NASA’s Curiosity rover has found evidence of the preservation of potential chemical biosignatures in the martian near surface. Although amino acids have not yet been identified by in situ measurements on Mars [5], indigenous achiral amino acids have been identified in one martian meteorite [6]. It is expected that amino acid racemization would be very slow and any chiral or isotopic signatures from an extinct martian biota could be preserved for billions of years, given the extremely cold and dry surface conditions [7]. The ESA/Roscosmos ExoMars mission scheduled for launch next year includes the Rosalind Franklin rover designed to acquire samples from a depth of ~2 m and deliver them to a suite of instruments, including the Mars Organic Molecule Analyzer (MOMA). The MOMA instrument contains a wet chemistry experiment designed specifically for the detection of amino acids and measurement of their enantiomeric compositions [8]. The complexity and limited duration of spaceflight operations, and the known analytical challenges associated with in situ extraction and characterization of trace reduced organic com-pounds in ancient rocks, make it challenging to determine the origins of martian organic matter found to date. Coordinated state-of-the-art laboratory measurements of returned samples from Mars that include spatially resolved chemical, mineralogical, bulk and molecule-specific isotopic, and enantiomeric measurements will be required to firmly establish whether the complex organic matter detected on Mars derives from bio-tic or abiotic processes. Ultimately, Mars Sample Return of rock cores collected by NASA’s Perseverance rover may be our best chance of identifying chemical biosignatures, including any chiral amino acid asymmetry resulting from a past or present martian biota, if one ever existed on Mars. Here we review our current knowledge of the distributions, and enantiomeric and isotopic com-positions of amino acids found in meteorites compared to terrestrial biochemistry. We also propose a set of measurement criteria that should be used to help establish the sources of any amino acids detected in samples returned from Mars using state-of-the-art gas and liquid chromatography mass spectrometry techniques [1].

D P Glavin↗

Electromagnetic Compatibility Test and Analysis Campaign of NASA's Mars 2020 Rover Final Submission

NASA's Mars 2020 Perseverance Rover—with a launch window opening July 2020, and landing expected February 2021—has mission objectives to look for evidence of habitability, seek biosignatures of past life, collect and cache samples for possible future return to Earth, and prepare for future human missions to Mars. The Rover platform is similar to the previous Mars Science Laboratory (MSL) “Curiosity” rover that landed in 2012 but contains a new suite of scientific instruments and upgrades to existing functionality: seven new and/or upgraded scientific payloads, an upgraded arm and sampling system, and a Helicopter demonstration. These changes—along with new efficiency goals to operate more Rover subsystems concurrently and thus collect more science—presented new electromagnetic compatibility (EMC) challenges. In this paper, we will describe the campaign to ensure Mars 2020 mission success from an electromagnetic environment perspective: 1) confirming existing MSL heritage subsystems and EMC requirements were compatible with the new Mars 2020 mission objectives, 2) engaging with engineers and scientists early in the project to identify and evaluate risks before hardware assembly and performing ambitious risk reduction tests, 3) undertaking a comprehensive subsystem qualification test program based on tailored MIL-STD-461F requirements, occasionally leading to redesign, 4) synthesizing the data collected to perform detailed analyses toward the goal of making risk-informed decisions at a system level. The spacecraft successfully completed all three planned system level tests, demonstrating self-compatibility with minimal impact to operations from electromagn

Gonzales, Edward C↗

Electromagnetic Compatibility Test and Analysis Campaign of NASA's Mars 2020 Rover

NASA's Mars 2020 Rover—with a launch window opening July 2020, and landing expected February 2021—has mission objectives to look for evidence of habitability, seek biosignatures of past life, collect and cache samples for possible future return to Earth, and prepare for future human missions. The Rover platform is similar to the previous Mars Science Laboratory (MSL) “Curiosity” rover that landed in 2012 but contains a new suite of scientific instruments and upgrades to existing functionality. The scientific payload includes a trio of chemical analysis tools (PIXL, SHERLOC, SuperCam), a ground penetrating radar (RIMFAX), an upgraded weather station (MEDA), upgraded high resolution camera (MastCam-Z), and an oxygen-producing experiment (MOXIE). These changes—along with new efficiency goals to operate more Rover subsystems concurrently and thus collect more science—presented new electromagnetic compatibility (EMC) challenges. In this paper, we will describe the campaign to ensure Mars 2020 mission success from an electromagnetic environment perspective: 1) confirming existing MSL heritage subsystems and EMC requirements were compatible with the new Mars 2020 mission objectives, 2) engaging with engineers and scientists early in the project to identify and evaluate risks before hardware assembly and performing ambitious risk reduction tests, 3) undertaking a comprehensive subsystem qualification test program based on tailored MIL-STD-461F requirements, occasionally leading to redesign, 4) synthesizing the data collected to perform detailed analyses toward the goal of making risk-informed decisions at a system level. The spacecraft has successfully completed all three planned system level tests, demonstrating self-compatibility with minimal impact to operations from electromagnetic interference in all mission phases.

Gonzales, Edward C↗

The Limiting Sizes of the Habitable Planets

The astrobiological problem of the occurrence of life in the universe is discussed from the standpoint of the size and nature of planets upon which living organisms might arise. The conclusion is tentatively drawn that the most likely radius of a habitable planet lies between 10(exp 8) cm and 2 x 10(exp 9) cm. Conditions of temperature and density also bear upon the occurrence of life; thus the moon and Mercury, although both fall within the range of favorable radii, are nevertheless believed uninhabited by indigeneous life.

Huang, Su-Shu↗

Volatiles and Isotopes and the Exploration of Ancient and Modern Martian Habitability with the Curiosity Rover

The Mars Science Laboratory Mission was designed to pave the way for the study of life beyond Earth through a search for a habitable environment in a carefully selected landing site on Mars. Its ongoing exploration of Gale Crater with the Curiosity Rover has provided a rich data set that revealed such an environment in an ancient lakebed [1]. Volatile and isotope measurements of both the atmosphere and solids contribute to our growing understanding of both modern and ancient environments.

curiosity rover↗

The Origins Space Telescope

The Origins Space Telescope will trace the history of our origins from the time dust and heavy elements permanently altered the cosmic landscape to present-day life. How did galaxies evolve from the earliest galactic systems to those found in the universe today? How do habitable planets form? How common are life-bearing worlds? To answer these alluring questions, Origins will operate at mid- and far-infrared wavelengths and offer powerful spectroscopic instruments and sensitivity three orders of magnitude better than that of Herschel, the largest telescope flown in space to date. After a 3 ½ year study, the Origins Science and Technology Definition Team will recommend to the Decadal Survey a concept for Origins with a 5.9-m diameter telescope cryo cooled to 4.5 K and equipped with three scientific instruments. A mid-infrared instrument (MISC-T) will measure the spectra of transiting exoplanets in the 2.8 – 20 μm wavelength range and offer unprecedented sensitivity, enabling definitive biosignature detections. The Far-IR Imager Polarimeter (FIP) will be able to survey thousands of square degrees with broadband imaging at 50 and 250 μm. The Origins Survey Spectrometer (OSS) will cover wavelengths from 25 – 588 μm, make wide-area and deep spectroscopic surveys with spectral resolving power R ~ 300, and pointed observations at R ~ 40,000 and 300,000 with selectable instrument modes. Origins was designed to minimize complexity. The telescope has a Spitzer-like architecture and requires very few deployments after launch. The cryo-thermal system design leverages JWST technology and experience. A combination of current-state-of-the-art cryocoolers and next-generation detector technology will enable Origins’ natural background limited sensitivity.

Leisawitz, D.↗

The Origins Space Telescope: Trades and Decisions Leading to the Baseline Mission Concept

The Origins Space Telescope will trace the history of our origins from the time dust and heavy elements permanently altered the cosmic landscape to present-day life. How did galaxies evolve from the earliest galactic systems to those found in the universe today? How do habitable planets form? How common are life-bearing worlds? We describe how Origins was designed to answer these alluring questions. We discuss the key decisions taken by the Origins mission concept study team, the rationale for those choices, and how they led through an exploratory design process to the Origins baseline mission concept. To understand the concept solution space, we studied two distinct mission concepts and descoped the second concept, aiming to maximize science per dollar and hit a self-imposed cost target. We report on the study approach and describe the concept evolution. The resulting baseline design includes a 5.9-m diameter telescope cryocooled to 4.5 K and equipped with three scientific instruments. The chosen architecture is similar to that of the Spitzer Space Telescope and requires very few deployments after launch. The cryo-thermal system design leverages JamesWebb Space Telescope technology and experience.

Infrared↗

The Origins Space Telescope: Baseline Mission Concept

The Origins Space Telescope will trace the history of our origins from the time dust and heavy elements permanently altered the cosmic landscape to present-day life. How did galaxies evolve from the earliest galactic systems to those found in the Universe today? How do habitable planets form? How common are life-bearing worlds? To answer these alluring questions, Origins will operate atmid- and far-infrared (IR) wavelengths and offer powerful spectroscopic instruments and sensitivity three orders of magnitude better than that of the Herschel Space Observatory, the largest telescope flown in space to date. We describe the baseline concept for Origins recommended to the 2020 US Decadal Survey in Astronomy and Astrophysics. The baseline design includes a 5.9-m diameter telescope cryocooled to 4.5 K and equipped with three scientific instruments. A mid-infrared instrument (Mid-Infrared Spectrometer and Camera Transit spectrometer) will measure the spectra of transiting exoplanets in the 2.8 to 20 μm wavelength range and offer unprecedented spectrophotometric precision, enabling definitive exoplanet biosignature detections. The far-IR imager polarimeter will be able to survey thousands of square degrees with broadband imaging at 50 and 250 μm. The Origins Survey Spectrometer will cover wavelengths from 25 to 588 μm, making wide-area and deep spectroscopic surveys with spectral resolving power R ∼ 300, and pointed observations at R ∼ 40;000 and 300,000 with selectable instrument modes. Origins was designed to minimize complexity. The architecture is similar to that of the Spitzer Space Telescope and requires very few deployments after launch, while the cryothermal system design leverages James Webb Space Telescope technology and experience. A combination of current-state-of-the-art cryocoolers and next-generation detector technology will enable Origins’ natural background-limited sensitivity.

David Leisawitz↗

The Origins Space Telescope

The Universe has never been seen like this before. The window into the infrared opens only above Earth's atmosphere, and humanity has barely glimpsed outside. About half of the light emitted by stars, planets, and galaxies over the lifetime of the Universe emerges in the infrared. With an unparalleled sensitivity increase — up to a factor of 1,000 more than any previous or planned mission — the advance offered by the Origins Space Telescope (OST) is akin to that from the naked eye to humanity's first telescope, or from Galileo's first telescope to the first telescope in space. While key path-finding missions have glimpsed a rich infrared cosmos, extraordinary discovery space awaits; the time for a far-infrared revolution has begun.Are we alone or is life common in the Universe? OST will directly address this long-standing question by searching for signs of life in the atmospheres of potentially habitable terrestrial planets transiting M dwarf stars. How do planets become habitable? OST will trace the trail of cold water from the interstellar medium, through protoplanetary disks and into the outer reaches of our own Solar System. How do stars, galaxies, black holes and the elements of life form, from the cosmic dawn to today? With broad wavelength coverage and fast mapping speeds, OST will map millions of galaxies, simultaneously measuring star formation rates and black hole growth across cosmic time, peering deeper into the far reaches of the Universe than ever before.OST will be maintained at a temperature of 4 K, enabling its tremendous sensitivity gain, and will operate from 5 m to 600 m, encompassing the mid- and far-infrared. OST has two Mission Concepts: Concept 1 with a 9.1-m deployed off-axis primary, and Concept 2, described here, a non-deployed 5.9-m on-axis telescope with the equivalent collecting area of the James Webb Space Telescope (JWST). Concept 2 includes four instruments with capabilities for imaging (large surveys and pointed), spectroscopy (survey and high-resolution modes) and polarimetry, as well as an instrument for high-precision spectroscopy of transiting exoplanets. Concept 2 is optimized for maximum science return and minimal complexity, and offers fast mapping (approximately 60 arcseconds per second). We describe here the three key science themes for OST and the basic mission specifications.

Battersby, Cara↗

Autonomous Ocean World Exploration: Advancement of a Virtual Testbed

The search for life (extinct or extant) and potentially habitable bodies in our solar system and beyond is one of the 12 priority science questions outlined in the National Acadamies’ 2022 decadal survey [5]. Extraterrestrial destinations containing liquid water present an opportunity to search for life as we know it, and in recent years an increasing number of such locations have been discovered within our solar system. Several Jovian moons—Europa, Ganymede, and Callisto [10]—and the Saturnian moons Enceladus [8] and Titan [9] are known or suspected to harbor massive subsurface oceans. Of these "ocean worlds", Europa is the focus of at least one planned NASA orbiter mission, Europa Clipper [4], and an early lander mission concept, the Europa Lander [2, 3]. Whereas most robotic missions to the Moon and Mars (e.g. orbiters, rovers, landers) to date have had ground controllers on Earth tightly involved in mission operations, missions to more distant worlds will require a high degree of onboard autonomy due to long communication lags and blackouts, harsh environments (radiation, cold), and more limited battery and hardware life. The past decade has seen great advances in both AI technologies and computing scalability and performance that offer promising solutions for spacecraft autonomy and motivate the software system and research programs described in this paper. The Ocean Worlds Autonomy Testbed for Exploration, Research, and Simulation (OceanWATERS) [1], which has been in development at the NASA Ames Research Center since 2018, is a virtual environment for testing lander autonomy solutions. It is built on the Robot Operating System (ROS), runs on consumer-grade Linux workstations, and was released as open source in 2020. OceanWATERS provides a physical and visual simulation of a prototypical lander in a Europa-like environment (Figure 1). The lander was modeled after requirements and specifications made in JPL’s Europa Lander Study of 2016 [3]. Simulated lander systems include stereo cameras and spotlights mounted on an antenna mast that pans and tilts, a 6 degrees of freedom (DoF) robotic arm with a force-torque sensor and two interchangeable end effectors, and a battery pack power system. The environment consists of multiple terrain models including a highly detailed model sourced from the FROST dataset [11], simulation of surrounding planetary bodies based on an ephemeris model, and lighting from the sun with associated surface illumination, reflectance, and shadows. Operations supported by OceanWATERS include panoramic and directed imaging of the environment and lander workspace, Cartesian and joint-level arm commanding, grinding of the terrain surface (e.g. digging a trench), and scooping of ground material (Figure 2) which can be discarded or collected as science samples in a receptacle that can be emptied (science operations themselves are not simulated). These operations are realized as ROS Actions and are complimented by a wide selection of telemetry that is continually produced by each lander subsystem. The power system model is driven by the open-source Generic Software Architecture for Prognostics (GSAP) [11] that predicts the battery’s remaining useful life and other characteristics. As a testbed for high-level autonomy, OceanWATERS provides an execution framework based on PLEXIL [12], an open-source plan specification language and execution engine developed largely at Ames. NASA's initial development of OceanWATERS, as well the Ocean Worlds Lander Autonomy Testbed (OWLAT) [6], a complimentary physical testbed developed at JPL, was the first step in a plan for realizing candidate onboard autonomy solutions for such planetary landers. In 2020 NASA solicited applications for its Autonomous Robotics Research for Ocean Worlds (ARROW) program, and in 2021 the similar Concepts for Ocean worlds Life Detection Technology (COLDTech) program. Collectively six research teams, based in universities and companies across the United States, were awarded grants to develop and demonstrate autonomy solutions on OceanWATERS and OWLAT. These 1–2-year projects have now finished or are nearing completion, and a wide variety of autonomy challenges in ocean world surface missions were addressed. Prototyped and demonstrated solutions have included autonomous discovery, response and adaptation to system faults and unexpected environmental events, world model synthesis through perception, plan synthesis using learned models, methods to optimize sample target selection and prioritize science data transmission, extension of PLEXIL for stochastic decision-making, and an integration of a model of JPL’s mission-ready COLDArm [7]. Technologies used in these projects include many forms of machine learning, causal reasoning, automated planning, Markov decision processes, formal methods, and other advanced techniques. A more detailed summary of the ARROW and COLDTech projects is given herein. OceanWATERS has had significant enhancements since its open-source release in 2020. Many of its new features were driven or shaped by feedback from the ARROW and COLDTech teams and requirements of their projects. In support of enabling autonomous adaptation to spacecraft faults (a specific capability solicited by both programs), a fault injection and detection framework was developed that supports a wide and growing range of fault types such as locked joints, image loss, and battery failures. The power system model was completed and integrated into the simulator, starting as a single-cell battery model and later upgraded to a multi-cell model with associated faults such as cell disconnection. Arm/terrain interaction was improved by adding a force-torque sensor and associated faults, and an analytic dig force model based on the Balovnev bucket force equations. Environment fidelity was increased by modeling terrain deformation resulting from digging and scooping; visual improvements were made in textures, lighting, and shadows. To facilitate interoperation with OWLAT, a unified command and telemetry interface between the testbeds was developed at the ROS level, along with a PLEXIL interface. The number of lander operations was greatly expanded (e.g. with Cartesian-based arm and antenna movement), and a framework was designed for users to build their own lander actions. A GUI for PLEXIL plan selection was created (Figure 3), and an expansive set of plans were added, such as those that illustrate patterns for fault handling. This paper provides a self-contained high-level description of OceanWATERS, focusing on more detailed coverage of the aforementioned enhancements. It provides a high-level summary of the projects undertaken by participants in the ARROW and COLDTech programs and how these efforts have helped shape OceanWATERS. Finally, potential future work and directions for the testbed are listed, as likely informed by the recent planetary science decadal survey [5].

K Michael Dalal↗

Astrobiology Extends Biology into Deep Time and Space

To understand our own origins and to search for biospheres beyond Earth, we need a more robust concept of life itself. We must learn how to discriminate between attributes that are fundamental to all living systems versus those that represent principally local outcomes of long-term survival on Earth. We should identify the most basic environmental needs of life, chart the distribution of other habitable worlds, and understand the factors that created their distribution. Studies of microbial communities and the geologic record will be summarized that offer clues about the early evolution of our own biosphere as well as the signatures of life that we might find in the heavens.

Desmarais, David↗

Space Station life sciences guidelines for nonhuman experiment accommodation

Life scientists will utilize one of four habitable modules which constitute the initial Space Station configuration. This module will be initially employed for studies related to nonhuman and human life sciences. At a later date, a new module, devoted entirely to nonhuman life sciences will be launched. This report presents a description of the characteristics of a Space Station laboratory facility from the standpoint of nonhuman research requirements. Attention is given to the science rationale for experiments which support applied medical research and basic gravitational biology, mission profiles and typical equipment and subsystem descriptions, issues associated with the accommodation of nonhuman life sciences on the Space Station, and conceptual designs for the initial operational capability configuration and later Space Station life-sciences research facilities.

Arno, R.↗

The Influence of Power Limitations on Closed Environment Life Support System Applications

The future of manned space exploration will be determined through a process which balances the innate need of humanity to explore its surroundings and the costs associated with accomplishing these goals. For NASA, this balance is derived from economics and budgetary constraints that hold it accountable for the expenditure of public funds. These budgetary realities demand a reduction in cost and expenditures of exploration and research activities. For missions venturing out to the edge of habitability, the development of cost effective life support approaches will have a significant influence on mission viability. Over the past several years, a variety of mission scenarios for potential Lunar and Mars missions have been developed. The most promising of these scenarios attempt to provide basic mission requirements at a minimum cost. As a result, these scenarios are extremely power limited. For Closed Environment Life Support System (CELSS) applications, these realities impose both limitations and direction to future research. This paper presents a summary of these mission scenarios and an evaluation of the impact which these power limitations will have on CELSS system design.

Flynn, Michael↗

Astrobiological Significance of Definitive Mineralogical Analysis of Martian Surface Samples Using the CheMin XRD/XRF Instrument

The search for evidence of habitability, or of extant or extinct life on Mars, will initially be a search for evidence of past or present conditions supportive of life. The three key requirements for the emergence of life are thought to be liquid water; a suitable energy source; and chemical building blocks. CheMin is a miniaturized XRD/XRF (X-Ray diffraction / X-ray fluorescence) instrument which has been developed for definitive mineralogic analysis of soils and rocks on the Martian surface. The CheMin instrument can provide information that is highly relevant to each of these habitability requirements as summarized below.

Feldman, S. M.↗

Late biological effects of heavy charged particles: Cataracts, vascular injury and life shortening in mice

Risks associated with extended habitation in a space environment, particularly hazards to space workers that might result from exposure to high energy heavy ion particles (HZE), were studied. Biological effects of HZE were investigated in mice to assess their potential adverse health hazards. The potential effects of HZE particles on the crystalline lens of the eye and the carcinogenic effects and blood vessel (vascular) damage from radiation were evaluated by a risk assessment. Animal experiments to evaluate dose response relationships for tumor induction/promotion and for vascular injury were introduced. Cataract productions and preliminary results on cacinogenic and vascular effects are presented for perspective.

Ainsworth, E. J.↗