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At least 235 records · Page 13

House Advantage or House of Cards? Stacking the Deck for Data Videos Leads to Null Results: Preprint

Videos are becoming a ubiquitous means of sharing information on social media platforms. In response, data videos - short clips combining visualization with dynamic storytelling, audio descriptions, and spatial referencing - have gained popularity for communicating data. These affordances suggest that data videos might communicate data patterns, trends, and concepts more effectively than static visualizations, enhancing comprehension. However, existing research has not systematically tested this claim. To address this gap, we conducted three controlled studies to measure comprehension differences between data videos and static visualizations. Despite leveraging visual cues and audio explanations, no data video led to significantly better comprehension than an analogous static visualization. Our results suggest data videos are not categorically better and that future research should examine the tradeoffs between their engagement benefits and costs.

97 MATHEMATICS AND COMPUTING↗

Mechanoregulation of Proliferation, Differentiation, Senescence and Survival of Bone Marrow Primary Osteoprecursor Cells

Cell and animal studies conducted onboard the International Space Station and during the Shuttle program have provided extensive data illustrating bone degenerative responses to mechanical unloading in microgravity. Specifically CDKN1a/p21, an inhibitory modulator of cell cycle progression, is upregulated in osteoprecursor cells of the femur during 15-day spaceflight, suggesting that microgravity can block stem cell-based tissue regenerative process at the level of progenitor proliferation and differentiation. To study a potential role for CDKN1a/p21 in regulating osteogenic mechanosensitivity, we cultured primary bone marrow osteoprogenitor cells from CDKN1a/p21-null (p21-null) and wildtype mice with and without mechanical stimulation, and compared their morphological, proliferative, and in-vitro mineralization responses. Structural cell alterations due to mechanical stimulation were assessed by florescence labeling of f-actin cytoskeleton and focal adhesions. Mechanical stimulation of p21-null cells resulted in more pronounced cytoskeletal alignment with the axis of stretch than for wildtype cells. In addition, p21-null cells subjected to stretch loading also formed significantly more focal adhesions than wildtype cells. Combined these findings suggest that p21-null cells are structurally more responsive to stretch stimulation than the wildtype cells. Because osteoprogenitor cells are well known to respond to mechanical stimulation with increased proliferation, we also tested this response in p21-null cells. Results from those experiments show the proliferative capacity of mechanically stimulated p21-null cells far exceeded that of wildtype controls. Specifically, cell counts from 14, and 21 days post mechanical stimulation, show that p21- null cells to have a 4-fold increase in proliferation compared to wildtype. When the p21-null cell differentiation response to mechanical stimulation was evaluated, the p21-null cultuers elicited more extensive mineralization at earlier assessed timepoints than control cultures. Specifically, Von Kossa staining for mineralized matrix showed that the p21-null cells produced more than twice the mineralized surface area of wildtype cells, and at an earlier 7-day time point in culture. Taken together these results suggest that CDKN1a/p21 normally plays a role in negatively regulating osteoprogenitor proliferation and differentiation responses to mechanostimulation in bone. Findings of CDKN1a/p21's increased expression during spaceflight in microgravity also suggest not only a potential molecular mechanism for arresting regenerative bone growth in space, but potentially also a reduced impact for bone-formation-promoting exercise mechanostimulation. The findings described here constitute a novel role for p21 as a regulator of tissue regeneration in response to mechanical load stimulation, and also suggest a new promising molecular target to promote regenerative health in disuse conditions.

gravity↗

Mid-infrared nuller for Terrestrial Planet Finder: design progress and results

Nulling interferometry shows promise as a technique enabling investigation of faint objects such as planets and exo-zodiacal dust around nearby stars. At Jet Propulsion Laboratory, a nulling beam combiner based on a design built for the Keck Observatory in Hawaii has been used to pursue deep and stable narrowband nulls. We describe the design and layout of the Modified Mach Zehnder TPF nuller, and the results achieved in the laboratory to date. We report the stabilized 900,000 nulls achieved using a CO2 laser, and discuss the performance limitations and way forward to the deep, broadband nulls required for a space-borne nulling interferometer mission. We show briefly the results from Keck breadboard experiments: broadband transient nulls centered around 10.6 micron have been achieved ranging between 17500 at 18% bandwidth and 7500:1 at 29% bandwidth.

Serabyn, E.↗

Simulations of the churning mode: Toroidally symmetric plasma convection and turbulence around the X-points in a snowflake divertor

Using a reduced MHD model, extended to include field-aligned thermal conduction, we present numerical simulations of the churning mode (CM): a toroidally symmetric, non-linear plasma vortex in the vicinity of the null points in a snowflake (SF) divertor [D. D. Ryutov et al., Phys. Scr. 89, 088002 (2014)]. Simulations are carried out across a range of inter-null separations, d xx ⁠, and inter-null orientations, θ⁠, primarily in conditions relevant to the MAST-U tokamak. We find that, when d xx is small, the CM induces additional transport across the X-points when β pm ≳8%, where β pm is the ratio of the plasma pressure in the null region to poloidal magnetic pressure at the midplane. This transport also increases approximately linearly as d xx is reduced. A diffusive model of this transport is shown to predict the total transport across the null points, where diffusion coefficients of up to ∼ 10 2 m 2 s −1 centered on a small region around the X-points are used. However, the CM also results in significant changes to the flux surfaces in the null region, which is not captured by this diffusive model. The changes in magnetic geometry mean the fractional exhaust power delivered to each divertor leg is highly sensitive to β pm ⁠, d xx ⁠, and θ⁠. For small values of θ⁠, the CM can induce a change in topology, redirecting exhaust power from a secondary divertor leg on the high field side to one on the low field side. Similar behavior is found in the fraction of exhaust power going to the inner and outer divertor. Such changes in the flux surfaces may not be captured by Grad–Shafranov solvers and so may be a source of error in the magnetic reconstruction of SF experiments. We consistently find that the fractional exhaust power going to a secondary divertor leg on the high field side is small, consistent with SF experiments.

Computer simulation↗

Magnetohydrodynamic Wave Mode Conversion in a Pseudostreamer Structure

The interaction of a fast magnetoacoustic wave with a magnetic null point in a pseudostreamer magnetic configuration is modeled. The incident fast wave is excited by an impulsive velocity driver located in the corona outside the Alfvén-acoustic equipartition layer. The fast wave front experiences refraction and wraps around the null point, while the front segment approaching the null point along the magnetic bisector passes through it. In the equipartition layer surrounding the null point, part of the fast wave energy is converted into slow magnetoacoustic waves. Slow waves propagate outward from the null point along the magnetic separatrices. The fronts of slow waves exhibit a characteristic chevron shape. The fast-to-slow mode conversion efficiency increases with the width of the initial perturbation, following a power-law dependence with an index of approximately 1.06. For initial wave amplitudes below about 10% of the local Alfvén speed, the dependence of the conversion efficiency on the initial amplitude is weak. After interacting with the null point, the amplitudes of the fast waves decrease significantly owing to energy conversion and the spreading of wave energy over a broad spatial domain. In contrast, the energy of slow waves remains concentrated in the vicinity of the magnetic separatrices, resulting in less pronounced geometric attenuation of these waves. These findings are consistent with observational reports of the interaction of a coronal fast wave with a pseudostreamer.

Zhong, Yu [Univ. of Warwick, Coventry (United King↗

The Hubble Space Telescope optical systems failure report

The findings of the Hubble Space Telescope Optical Systems Board of Investigation are reported. The Board was formed to determine the cause of the flaw in the telescope, how it occurred, and why it was not detected before launch. The Board conducted its investigation to include interviews with personnel involved in the fabrication and test of the telescope, review of documentation, and analysis and test of the equipment used in the fabrication of the telescope's mirrors. The investigation proved that the primary mirror was made in the wrong shape (a 0.4-wave rms wavefront error at 632.8 nm). The primary mirror was manufactured by the Perkin-Elmer Corporation (Hughes Danbury Optical Systems, Inc.). The critical optics used as a template in shaping the mirror, the reflective null corrector (RNC), consisted of two small mirrors and a lens. This unit had been preserved by the manufacturer exactly as it was during the manufacture of the mirror. When the Board measured the RNC, the lens was incorrectly spaced from the mirrors. Calculations of the effect of such displacement on the primary mirror show that the measured amount, 1.3 mm, accounts in detail for the amount and character of the observed image blurring. No verification of the reflective null corrector's dimensions was carried out by Perkin-Elmer after the original assembly. There were, however, clear indications of the problem from auxiliary optical tests made at the time. A special optical unit called an inverse null corrector, designed to mimic the reflection from a perfect primary mirror, was built and used to align the apparatus; when so used, it clearly showed the error in the reflective null corrector. A second null corrector was used to measure the vertex radius of the finished primary mirror. It, too, clearly showed the error in the primary mirror. Both indicators of error were discounted at the time as being themselves flawed. The Perkin-Elmer plan for fabricating the primary mirror placed complete reliance on the reflective null corrector as the only test to be used in both manufacturing and verifying the mirror's surface with the required precision. This methodology should have alerted NASA management to the fragility of the process and the possibility of gross error. Such errors had been seen in other telescope programs, yet no independent tests were planned, although some simple tests to protect against major error were considered and rejected. During the critical time period, there was great concern about cost and schedule, which further inhibited consideration of independent tests.

Source record↗

Integrated Optics Achromatic Nuller for Stellar Interferometry

This innovation will replace a beam combiner, a phase shifter, and a mode conditioner, thus simplifying the system design and alignment, and saving weight and space in future missions. This nuller is a dielectric-waveguide-based, four-port asymmetric coupler. Its nulling performance is based on the mode-sorting property of adiabatic asymmetric couplers that are intrinsically achromatic. This nuller has been designed, and its performance modeled, in the 6.5-micrometer to 9.25-micrometer spectral interval (36% bandwidth). The calculated suppression of starlight for this 15-cm-long device is 10(exp -5) or better through the whole bandwidth. This is enough to satisfy requirements of a flagship exoplanet-characterization mission. Nulling interferometry is an approach to starlight suppression that will allow the detection and spectral characterization of Earth-like exoplanets. Nulling interferometers separate the light originating from a dim planet from the bright starlight by placing the star at the bottom of a deep, destructive interference fringe, where the starlight is effectively cancelled, or nulled, thus allowing the faint off-axis light to be much more easily seen. This process is referred to as nulling of the starlight. Achromatic nulling technology is a critical component that provides the starlight suppression in interferometer-based observatories. Previously considered space-based interferometers are aimed at approximately 6-to-20-micrometer spectral range. While containing the spectral features of many gases that are considered to be signatures of life, it also offers better planet-to-star brightness ratio than shorter wavelengths. In the Integrated Optics Achromatic Nuller (IOAN) device, the two beams from the interferometer's collecting telescopes pass through the same focusing optic and are incident on the input of the nuller.

Ksendzov, Alexander↗

Measuring Extended Structure in Stars Using the Keck Interferometer Nuller

The Keck Interferometer Nuller is designed to detect faint off-axis mid-infrared light a few tens to a few hundreds of milliarcseconds from a bright central star. The starlight is suppressed by destructive combination along the long (85 m) baseline, which produces a fringe spacing of 25 mas at a wavelength of 10 m, with the central null crossing the position of the star. The strong, variable mid-infrared background is subtracted using interferometric phase chopping along the short (5 m) baseline. This paper presents an overview of the observing and data reduction strategies used to produce a calibrated measurement of the off-axis light. During the observations, the instrument cycles rapidly through several calibration and measurement steps, in order to monitor and stabilize the phases of the fringes produced by the various baselines, and to derive the fringe intensity at the constructive peak and destructive null along the long baseline. The data analysis involves removing biases and coherently demodulating the short-baseline fringe with the long-baseline fringe tuned to alternate between constructive and destructive phases, combining the results of many measurements to improve the sensitivity, and estimating the part of the null leakage signal which is associated with the finite angular size of the central star. Comparison of the results of null measurements on science target and calibrator stars permits the instrumental leakage - the "system null leakage" - to be removed and the off-axis light to be measured.

nulling interferometry↗

Accessing Small Inner Working Angles with a Rotating Sub-Aperture Nuller

A new approach to high contrast observations near bright stars with a single-aperture telescope is discussed, which is based on the idea of a rotating separated-aperture nulling interferometer. The approach can be described as a rotating sub-aperture nuller, because it nulls two or more sub-apertures within a single telescope's pupil, and uses baseline rotation to modulate the signals from off-axis sources in a manner similar to that of potential space-based nulling interferometers. The sub-aperture beams can be combined in a number of ways, including a fiber nuller and a rotational shearing interferometer. Such a rotating nulling coronagraph has two great advantages. First, it can be used on a ground-based telescope to test signal reconstruction approaches pertinent to potential space-based nulling interferometers. Moreover, it also has the potential to enable ground-based coronagraphic observations of faint off-axis companions very close to bright stars.

coronagraphy↗

Focal adhesion kinase is involved in mechanosensing during fibroblast migration

Focal adhesion kinase (FAK) is a non-receptor protein tyrosine kinase localized at focal adhesions and is believed to mediate adhesion-stimulated effects. Although ablation of FAK impairs cell movement, it is not clear whether FAK might be involved in the guidance of cell migration, a role consistent with its putative regulatory function. We have transfected FAK-null fibroblasts with FAK gene under the control of the tetracycline repression system. Cells were cultured on flexible polyacrylamide substrates for the detection of traction forces and the application of mechanical stimulation. Compared with control cells expressing wild-type FAK, FAK-null cells showed a decrease in migration speed and directional persistence. In addition, whereas FAK-expressing cells responded to exerted forces by reorienting their movements and forming prominent focal adhesions, FAK-null cells failed to show such responses. Furthermore, FAK-null cells showed impaired responses to decreases in substrate flexibility, which causes control cells to generate weaker traction forces and migrate away from soft substrates. Cells expressing Y397F FAK, which cannot be phosphorylated at a key tyrosine site, showed similar defects in migration pattern and force-induced reorientation as did FAK-null cells. However, other aspects of F397-FAK cells, including the responses to substrate flexibility and the amplification of focal adhesions upon mechanical stimulation, were similar to that of control cells. Our results suggest that FAK plays an important role in the response of migrating cells to mechanical input. In addition, phosphorylation at Tyr-397 is required for some, but not all, of the functions of FAK in cell migration.

NASA Discipline Cell Biology↗

Interferometry in the Era of Very Large Telescopes

Research in modern stellar interferometry has focused primarily on ground-based observatories, with very long baselines or large apertures, that have benefited from recent advances in fringe tracking, phase reconstruction, adaptive optics, guided optics, and modern detectors. As one example, a great deal of effort has been put into development of ground-based nulling interferometers. The nulling technique is the sparse aperture equivalent of conventional coronography used in filled aperture telescopes. In this mode the stellar light itself is suppressed by a destructive fringe, effectively enhancing the contrast of the circumstellar material located near the star. Nulling interferometry has helped to advance our understanding of the astrophysics of many distant objects by providing the spatial resolution necessary to localize the various faint emission sources near bright objects. We illustrate the current capabilities of this technique by describing the first scientific results from the Keck Interferometer Nuller that combines the light from the two largest optical telescopes in the world including new, unpublished measurements of exozodiacal dust disks. We discuss prospects in the near future for interferometry in general, the capabilities of secondary masking interferometry on very large telescopes, and of nulling interferometry using outriggers on very large telescopes. We discuss future development of a simplified space-borne NIR nulling architecture, the Fourier-Kelvin Stellar Interferometer, capable of detecting and characterizing an Earth twin in the near future and how such a mission would benefit from the optical wavelength coverage offered by large, ground-based instruments.

Barry, Richard K.↗

The Keck Interferometer Nuller

The Keck Interferometer Nuller (KIN), the first operational separated-aperture infrared nulling interferometer, was designed to null the mid-infrared emission from nearby stars so as to ease the measurement of faint circumstellar emission. This paper describes the basis of the KIN's four-beam, two-stage measurement approach and compares it 10 the simpler case of a two-beam nuller. In the four-beam KIN system, the starlight is first nulled in a pair of nullers operating on parallel 85 m Keck-Keck baselines, after which "cross-combination" on 4 m baselines across the Keck apertures is used to modulate and detect residual coherent off-axis emission. Comparison to the constructive itellar fringe provides calibration. The response to an extended source is similar in the two cases, except that the four-beam response includes a term due to the visibility of the source on the cross-combiner baseline-a small effect for relatively compact sources. The characteristics of the dominant null depth errors are also compared for the two cases. In the two-beam nuller, instrumental imperfections and asymmetries lead to a series of quadratic, positivedefinite null leakage terms. For the four-beam nuller, the leakage is instead a series of correlation cross-tenns combining corresponding errors in each of the two nullers, which contribute offsets only to the extent that these errors are correlated on the timescale of the measurement. This four-beam architecture has allowed a significant (approx. order of magnitude) improvement in mid-infrared long-baseline fringe-visibility accuracies.

Serabyn, E.↗

Terrestrial Planet Finder, Planet Detection Test-Bed: Latest Results of Planet Light Detection in the Presence of Starlight

The Terrestrial Planet Finder, Planet Detection Test-bed is a lab based simulation of the optics and control systems for the Terrestrial Planet Finder Interferometer mission. The test-bed supports starlight nulling at 10um infrared wavelengths, with fringe tracking at 2um wavelengths and angle and shear tracking at visible wavelengths. It further allows injection of simulated planet light in the presence of the nulled star light, to allow testing of planet detection methods. We will describe the detailed construction and operation of the test-bed from an optical and control system perspective. We will also report the latest results for narrow band nulls, and the detection of broad band planet light in the presence of nulled starlight.

Interferometry↗

New procedure for evaluation of U(3) coupling and recoupling coefficients

A simple method to calculate Wigner coupling coefficients and Racah recoupling coefficients for U(3) in two group–subgroup chains is presented. While the canonical U(3) coupling and recoupling coefficients are applicable to any system that respects U(3) symmetry, the U(3) coupling coefficients are more specific to nuclear structure studies. This new procedure precludes the use of binomial coefficients and alternating sums which were used in the 1973 formulation of Draayer and Akiyama, and in so doing provides a faster and more accurate determination of any and all required results. The resolution of the outer multiplicity is based on the null space concept of the U(3) generators proposed by Alex et al., whereas the inner multiplicity in the angular momentum subgroup chain is obtained from the dimension of the null space of the SO(3) raising operator. It is anticipated that a C++ library will ultimately be available for determining generic coupling and recoupling coefficients associated with both the canonical and the physical group–subgroup chains of U(3).

Cross-Coupling Reaction↗

Apparatus for providing a servo drive signal in a high-speed stepping interferometer

An analog voltage approximately linearly proportional to a desired offset from the present null position of a moving mirror in an interferometer is applied to the mirror moving means. As the mirror moves to the next null position, as determined by the analog voltage, the fringes of a laser reference interference pattern are detected. At the occurrence of each fringe the analog voltage is reduced proportionally so that when the next null position is reached, this driving analog is effectively zero. A binary up/down counter, by its internal count, causes a digital/analog converter to supply the analog voltage to the mirror moving means. Fringe detection and direction of movement logic cause the binary up/down counter to be decremented from its offset count as the mirror is moved to the new null position. Undesirable movement of the mirror due to vibration or other sources causes a correcting drive signal to be applied to the mirror moving means that is proportional to the distance of movement.

Schindler, R. A.↗

A near-optimum receiver structure for the detection of M-ary optical PPM signals

A class of receivers called conditionally nulling receivers is defined for quantum noise limited optical communications. These receivers have the ability to decide at each moment in time whether or not to coherently combine a predetermined local oscillator field with the received optical field, prior to performing an energy measurement (photodetection) on the combined field. Conditionally nulling receivers are applicable to pulse position modulation and related modulation schemes, which have the property that, at each moment in time, the transmitted signal is in one of only two states, on or off. The local oscillator field which may or may not be added by the receiver is an exact replica of the negative of the received on field; hence, the receiver can exactly null the on signal if the on signal is present and the receiver chooses to use the local field. An ideal conditionally nulling receiver achieves very nearly the same error probability (within a multiplicative factor varying froom 1 to 2.15) as the optimum quantum measurement for quantum noise limited detection of M-ary PPM signals. In contrast, other known receiving methods, such as direct, heterodyne, and homodyne detection, are exponentially suboptimum.

Dolinar, S. J., Jr.↗

Steering Law Design for Redundant Single Gimbal Control Moment Gyro Systems

The correspondence between robotic manipulators and single gimbal Control Moment Gyro (CMG) systems was exploited to aid in the understanding and design of single gimbal CMG Steering laws. A test for null motion near a singular CMG configuration was derived which is able to distinguish between escapable and unescapable singular states. Detailed analysis of the Jacobian matrix null-space was performed and results were used to develop and test a variety of single gimbal CMG steering laws. Computer simulations showed that all existing singularity avoidance methods are unable to avoid Elliptic internal singularities. A new null motion algorithm using the Moore-Penrose pseudoinverse, however, was shown by simulation to avoid Elliptic type singularities under certain conditions. The SR-inverse, with appropriate null motion was proposed as a general approach to singularity avoidance, because of its ability to avoid singularities through limited introduction of torque error. Simulation results confirmed the superior performance of this method compared to the other available and proposed pseudoinverse-based Steering laws.

Bedrossian, Nazareth Sarkis↗