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Gamma, X-ray, electron, or other radiation is used to shift threshold potentials of MOS devices on logic circuits. Before irradiation MOS gates to be shifted are biased positive and other gates are grounded to substrate. Threshold lasts 10 years. Thermal annealing brings circuit back to original configuration.
Evaluation of calculations and experimental evidence from 600-MeV proton irradiation indicating that cosmic-ray-induced radioactivity in detectors used to measure the diffuse gamma-ray background produces a significant counting rate in the energy region around 1 MeV. It is concluded that these counts may be responsible for the observed flattening of the diffuse photon spectrum at this energy.
A fused silica Mie Scattering Diffuser (MSD) has been developed at Ball Aerospace & Technology Corp. that has measured characteristics which could be used to increase the accuracy of the spectral albedo calibration of the Ozone Mapping and Profiler Suite (OMPS) Nadir ozone total column and profile instrument by almost an order of magnitude. Measurements have been made of the optical characteristics on both natural and synthetic forms of fused silica MSDs. Preliminary measurements suggest that MSDs are useable in the solar reflective wavelength region from 250 nm to 3.7 m. To date synthetic and natural MSDs have been irradiated for 60 hours of UV radiation from a solar simulator, and synthetic MSDs have been irradiated with increasing doses of Co-60 gamma rays at 30, 500 krads up to 1.5 Mrads, and 30 krads of 200 MeV protons. The principal effects have been small loses in transmittance at wavelengths < 350 nm. The high energy particle irradiation measurements were provided by Neal Nickles and Dean Spieth.
Spectra of gamma rays produced by interaction of 160 MeV protons with beryllium, carbon, oxygen, aluminum, cobalt, and bismuth
Gamma, electron, and proton radiation exposures of P-channel, enhancement, metal oxide semiconductor, and field effect transistors
Computer program contains an input library of nuclear data for 44 elements and their isotopes to determine the induced radioactivity for gamma emitters. Minimum input requires the irradiation history of the element, a four-energy-group neutron flux, specification of an alloy composition by elements, and selection of the output.
Study of detection sensitivities of 73 radioactive elements using fast unmoderated neutrons includes experiments for irradiation, cooling and counting conditions. The gamma ray emission spectra is used to identify the unknown material.
Point-kernel computation and experimental measurements of gamma heating effects during thermionic diode irradiation
The systems approach, theoretical measurement calculations, and preliminary measurements to be used in monitoring and mapping pollutants (such as traces of heavy metals) in the Chesapeake Bay are discussed. A neutron gamma-ray method is under development for demonstrating the system. The excitation source to be used is a machine accelerator using a deuterium/tritium reaction to produce 14-MeV neutrons. The neutrons excite characteristic gamma ray emission from the neutron irradiated surface. The discrete line emission produced can be used to infer both qualitative and quantitative elemental composition. A data preprocessor will accumulate, digitize, store, format, and prepare the data for transmission which can be accomplished by telephone, microwave, and possibly satellite link to central processors.
The effects of the surfaces of kaolinite and bentonite clays on the radiolysis and radioracemization of L-leucine and its hydrochloride salt have been investigated experimentally. L-leucine and its hydrochloride salt were deposited on the clays and the amino acid/clay preparations were irradiated by a Co-60 gamma-ray source which induced 2-89 percent radiolysis. The efficiency of radiolysis and radioracemization were measured using gas chromatography. Results were obtained for leucine in 0.1 M aqueous solution for comparison with the clay-deposted leucine and leucine hydrochloride. It is found that radiolysis and radioracemization in the samples occurred according to a pseudo-first-order rate law. Comparison of the specific rate constants showed that leucine and its hydrochloride salt were the most resistant to both radiolysis and radioracemization, followed by leucine and its hydrochloride salt on kaolin. Leucine and its HCl salt on bentonite, and leucine in aqueous solution were found to be the least resistant to radiolysis and radioracemization. The experimental results are intepreted with respect to the Vester-Ulbricht mechanism for the origin of optical activity.
Technique for detecting cavitation pitting in pumps, turbines, and other machinery uses low-level nuclear irradiation. Isotopes concentrated below surface emit gamma radiation, a portion of which is attenuated by overlying material. Where there are cavitation pits, output of gamma-ray detector fluctuates as detector is scanned near pits. Important to detect cavitation pits because nozzle, turbine blade, or other pump component weakened by cavitation could fail catastrophically and cause machine to explode.
Material presented at a NASA-sponsored workshop on risk models for exposure conditions relevant to prolonged space flight are described in this paper. Analyses used mortality data from experiments conducted at Argonne National Laboratory on the long-term effects of external whole-body irradiation on B6CF1 mice by 60Co gamma rays and fission neutrons delivered as a single exposure or protracted over either 24 or 60 once-weekly exposures. The maximum dose considered was restricted to 1 Gy for neutrons and 10 Gy for gamma rays. Proportional hazard models were used to investigate the shape of the dose response at these lower doses for deaths caused by solid-tissue tumors and tumors of either connective or epithelial tissue origin. For protracted exposures, a significant mortality effect was detected at a neutron dose of 14 cGy and a gamma-ray dose of 3 Gy. For single exposures, radiation-induced mortality for neutrons also occurred within the range of 10-20 cGy, but dropped to 86 cGy for gamma rays. Plots of risk relative to control estimated for each observed dose gave a visual impression of nonlinearity for both neutrons and gamma rays. At least for solid-tissue tumors, male and female mortality was nearly identical for gamma-ray exposures, but mortality risks for females were higher than for males for neutron exposures. As expected, protracting the gamma-ray dose reduced mortality risks. Although curvature consistent with that observed visually could be detected by a model parameterized to detect curvature, a relative risk term containing only a simple term for total dose was usually sufficient to describe the dose response. Although detectable mortality for the three pathology end points considered typically occurred at the same level of dose, the highest risks were almost always associated with deaths caused by tumors of epithelial tissue origin.
Co-60 gamma radiation damage in Li-doped p-n and conventional n-p solar cells
High-linear energy transfer (LET) ionizing radiation is a major health hazard for astronauts who will be exposed to galactic cosmic rays during upcoming lunar and Mars missions. Predicting and mitigating personalized health risks from space radiation exposure requires understanding the factors underlying individual radiation sensitivity, which currently remain unknown. We started to address this challenge by identifying the genomic and demographic associations with sensitivity to low and high-LET ionizing radiation in the largest human sample cohort to date and by evaluating baseline DNA damage as a potential predictor of radiation responses. We have collected and irradiated peripheral blood mononuclear cells (PBMCs) from 768 healthy donors of matched ethnicity, 50/50 male/female, 18-70 years old. We have analyzed the responses of 576 donor PBMCs to irradiation with simulated galactic cosmic ray components: 350MeV/n 28Si, 350MeV/n 40Ar and 600MeV/n 56Fe, at 1.1 and 3 particles/100μm2 fluences, as well as 0.1Gy and 1Gy doses of gamma rays, at 4 and 24 hours post irradiation. We quantified post-irradiation DNA repair based on radiation-induced 53BP1+ foci formation, together with oxidative stress and cell death using a flow cytometry-based assay. We also assessed baseline levels of DNA repair in PBMCs at the time of sample collection prior to irradiation experiments. We observed a wide variability of subject- and LET-dependent radiation responses, with radiation-induced DNA repair foci increasing with LET, though oxidative stress being notably reduced by high-LET irradiation, potentially due to a switch between hydrogen peroxide and oxygen radical-based mechanisms. We also identified a relationship between few DNA repair foci at baseline and increased DNA repair after irradiation, accompanied by an alteration in immunoregulatory cytokine secretion, which might be adapted as biomarkers to predict ionizing radiation sensitivity. Among demographic variables, baseline foci levels were positively associated with age and latent cytomegalovirus infection. Finally, we have performed low-throughput whole genome sequencing of all samples and are currently in process of identifying the genes and pathways associated with low and high-LET ionizing radiation sensitivity in humans.
Future Ge spectrometers flown in space to observe cosmic gamma-ray sources will incorporate segmented detectors to reduce the background from radioactivity produced by energetic particle reactions. To demonstrate the effectiveness of a segmented Ge detector in rejecting background events due to the beta decay of internal radioactivity, a laboratory experiment has been carried out in which radioactivity was produced in the detector by neutron irradiation. A Cf-252 source of neutrons was used to produce, by neutron capture on Ge-74 (36.5 percent of natural Ge) in the detector itself, Ge-75 (t sub 1/2 = 82.78 min), which decays by beta emission with a maximum electron kinetic energy of 1188 keV. By requiring that an ionizing event deposit energy in two or more of the five segments of the detector, each about 1-cm thick, the beta particles, which have a range of about 1-mm, are rejected, while most external gamma rays incident on the detector are counted. Analysis of this experiment indicates that over 85 percent of the beta events from the decay of Ge-75 are rejected, which is in good agreement with Monte Carlo calculations.
Fischer rat thyroid cells were grown under low-shear stress in a bioreactor to a stage of organization composed of integrated follicles resembling small thyroid glands prior to exposure to 3 Gray-gamma radiation. Bioreactor tissues and controls (both irradiated and non-irradiated) were harvested at 24, 48, 96 and 144 hours post-exposure. Tissue samples were fixed and fluorescently labeled for actin and microtubules. Tissues were assessed for changes in cytoskeletal components induced by radiation and quantified by laser scanning cytometry. ELISA's were used to quantify transforming growth factor-beta and thyroxin released from cells to the culture supernatant. Tissue architecture was disrupted by exposure to radiation with the structural organization of actin and loss of follicular content the most obviously affected. With time post-irradiation the actin appeared disordered and the levels of fluorescence associated with filamentous-actin and microtubules cycled in the tissue analogs, but not in the flask-grown cultures. Active transforming growth factor-beta was higher in supernatants from the irradiated bioreactor tissue. Thyroxin release paralleled cell survival in the bioreactors and control cultures. Thus, the engineered tissue responses to radiation differed from those of conventional tissue culture making it a potentially better mimic of the in vivo situation.
The properties were studied of a new class of gamma ray sources consisting of millisecond pulsars totally or partially surrounded by evaporating material from irradiated companion stars. Hidden millisecond pulsars offer a unique possibility to study gamma ray, optical and radio emission from vaporizing binaries. The relevance of this class of binaries for GRO observations and interpretation of COS-B data is emphasized.
The properties were studied of a new class of gamma ray sources consisting of millisecond pulsars totally or partially surrounded by evaporating material from irradiated companion stars. Hidden millisecond pulsars offer a unique possibility to study gamma ray, optical and radio emission from vaporizing binaries. The relevance of this class of binaries for GRO observations and interpretation of COS-B data is emphasized.