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At least 253 records · Page 14

Uniform Distribution Technique for Neutrino Beam Scan Simulation

In Fermilab's neutrino facilities such as the Neutrinos at the Main Injector (NuMI) and the upcoming Long Baseline Neutrino Facility (LBNF), a proton beam strikes high-power target, producing positively and negatively charged pions and kaons. There is a need for detailed simulations in order to capture all particle interactions and beam propagation from protons on target to short-lived mesons decaying into muons and neutrinos. The generation of individual beam simulations is a resource-intensive and time-consuming process. In this paper, we describe a method through which many simulation samples with high statistics can be generated to study the effects of beam scan across a target for given beam configurations.

43 PARTICLE ACCELERATORS↗

Normal Tissue Injury Induced by Photon and Proton Therapies: Gaps and Opportunities

Despite technological advances in radiation therapy (RT) and cancer treatment, patients still experience adverse effects. Proton therapy (PT) has emerged as a valuable RT modality that can improve treatment outcomes. Normal tissue injury is an important determinant of the outcome; therefore, for this review, we analyzed 2 databases: (1) clinical trials registered with ClinicalTrials.gov and (2) the literature on PT in PubMed, which shows a steady increase in the number of publications. Most studies in PT registered with ClinicalTrials.gov with results available are nonrandomized early phase studies with a relatively small number of patients enrolled. From the larger database of nonrandomized trials, we listed adverse events in specific organs/sites among patients with cancer who are treated with photons and protons to identify critical issues. The present data demonstrate dosimetric advantages of PT with favorable toxicity profiles and form the basis for comparative randomized prospective trials. A comparative analysis of 3 recently completed randomized trials for normal tissue toxicities suggests that for early stage non-small cell lung cancer, no meaningful comparison could be made between stereotactic body RT and stereotactic body PT due to low accrual (NCT01511081). In addition, for locally advanced non-small cell lung cancer, a comparison of intensity modulated RT with passive scattering PT (now largely replaced by spot-scanned intensity modulated PT), PT did not provide any benefit in normal tissue toxicity or locoregional failure over photon therapy. Finally, for locally advanced esophageal cancer, proton beam therapy provided a lower total toxicity burden but did not improve progression-free survival and quality of life (NCT01512589). The purpose of this review is to inform the limitations of current trials looking at protons and photons, considering that advances in technology, physics, and biology are a continuum, and to advocate for future trials geared toward accurate precision RT that need to be viewed as an iterative process in a defined path toward delivering optimal radiation treatment. A foundational understanding of the radiobiologic differences between protons and photons in tumor and normal tissue responses is fundamental to, and necessary for, determining the suitability of a given type of biologically optimized RT to a patient or cohort.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Young Adult Populations Face Yet Another Barrier to Care With Insurers: Limited Access to Proton Therapy

Young patients, including pediatric, adolescent, and young adult (YA) patients, are most likely to benefit from the reduced integral dose of proton beam radiation therapy (PBT) resulting in fewer late toxicities and secondary malignancies. This study sought to examine insurance approval and appeal outcomes for PBT among YA patients compared with pediatric patients at a large-volume proton therapy center.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Diagnosing Ghost Bunches with the Upstream Extinction Monitor in the Mu2e Experiment

The Mu2e experiment has a stringent requirement for extinction of the pulsed proton beam, referring to the elimination of particles between proton bunches to a relative level of 10$^-10$, which means a single out-of-time particle in the inter-pulse gaps for every 250 complete proton pulses. As the construction of the Mu2e experiment nears completion, it is crucially important to make an early measurement of the beam extinction in its current condition. Hence the upstream extinction monitor was constructed and operated to probe for problems in the proton pulse structure or a higher than expected incidence rate of out-of-time particles. The analysis in this work comes from data taken in March 2026. The long data run showed a significant presence of out-of-time particles from ghost bunches in the Delivery Ring approximately 388 ns after the centers of the main proton pulses. These are hypothesized to be the result of a combination of a RF frequency mismatch, particle space charge, and machine impedance during the rebunching sequence in the Recycler Ring, which can lead to particles leaking into adjacent buckets, but further studies and simulations are needed to confirm this

Hensley, R. [UC, Davis] (ORCID:0000000216064485)↗

Resonant Extraction and Extinction Measurement for the Mu2e Experiment

The Mu2e experiment, currently under construction at Fermilab, will search for coherent neutrinoless muon to electron conversion, extending the sensitivity of searches for charged lepton flavour violation by four orders of magnitude in 3-5 years of data-taking. This improved sensitivity is made possible by using a pulsed beam structure that is optimized for reducing prompt backgrounds when muons are stopped on an aluminium target. Producing a high-rate pulsed beam is achieved using resonant extraction of a circulating proton beam, an “AC dipole” with a time-varying field to deflect out-of-time protons, and a system to measure the extinction of out-of-time beam particles incident on the muon production target. These proceedings summarize the systems that have been designed to achieve the required level of extinction and to continuously place limits on the presence of out-of-time beam hitting the production target with a sensitivity of <1e-10.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

HL-LHC Beam Dynamics with Hollow Electron Lenses

Each of the two proton beams in the High-Luminosity Large Hadron Collider (HL-LHC) will carry a total energy of 720 MJ. One concern for machine protection is the energy stored in the transverse beam tails, estimated to potentially reach up to 5% of the total stored energy. Several failure scenarios could drive these tails into the collimators, potentially causing damage and therefore severely affecting operational efficiency. Hollow Electron Lenses (HEL) were integrated in the HL-LHC baseline to mitigate this risk by depleting the tails in a controlled way. A hollow-shaped electron beam runs co-axially to the hadron beam over about 3 m, such that halo particles at large amplitudes become unstable, while core particles ideally remain undisturbed. Residual fields from e-beam asymmetries can, however, induce emittance growth of the beam core. Various options for the pulsing of the HEL are considered and are compared using two figures of merit: halo depletion efficiency and core emittance growth. This contribution presents simulations for these two effects with different HEL pulsing modes using the final HL-LHC optics, that was optimized at the location of the lenses.

43 PARTICLE ACCELERATORS↗

Shielding development for the VENUS imaging instrument

VENUS is an imaging instrument that will use a broad range of neutron wavelengths, from epithermal to cold, will include enhanced contrast mechanisms, and will offer novel energy-selective imaging techniques that directly connect the structures, properties, and function of complex engineering materials and systems to reveal practical and fundamental answers about their real-world performance. The instrument is to be built at SNS beam line 10 and will face the decoupled poisoned hydrogen moderator. The driving cost for the instrument is the beam line and instrument cave shielding. Initial scoping analyses were performed to estimate thickness and composition of shielding materials for the instrument cave and beam line. In light of the upcoming Proton Power Upgrade (PPU) project, these transport analyses were performed for proton beam on target at 1.3 GeV and 2 MW.

Popova, Irina I.↗

Radiation Tests of the Extravehicular Mobility Unit Space Suit for the International Space Station Using Energetic Protons

Measurements using silicon detectors to characterize the radiation transmitted through the EMU space suit and a human phantom have been performed using 155 and 250 MeV proton beams at LLUMC. The beams simulate radiation encountered in space, where trapped protons having kinetic energies on the order of 100 MeV are copious. Protons with 100 MeV kinetic energy and above can penetrate many centimeters of water or other light materials, so that astronauts exposed to such energetic particles will receive doses to their internal organs. This dose can be enhanced or reduced by shielding - either from the space suit or the self-shielding of the body - but minimization of the risk depends on details of the incident particle flux (in particular the energy spectrum) and on the dose responses of the various critical organs. Data were taken to characterize the beams and to calibrate the detectors using the beam in a treatment room at LLUPTF, in preparation for an experiment with the same beams incident on detectors placed in a human phantom within the EMU suit. Nuclear interactions of high-energy protons in various materials produce a small flux of highly ionizing, low-energy secondary radiation. Secondaries are of interest for their biological effects, since they cause doses and especially dose-equivalents to increase relative to the values expected simply from ionization energy loss along the Bragg curve. Because many secondaries have very short ranges, they are best measured in passive track detectors such as CR-39. The silicon detector data presented here are intended to supplement the CR-39 data in regions where silicon has greater sensitivity, in particular the portion of the LET spectrum below 5 keV/micron. The results obtained in this study suggest that optimizing the radiation shielding properties of space suits is a formidable task. The naive assumption that adding mass can reduce risk is not supported by the data, which show that reducing the dose delivered at or near the skin by low-energy particles may increase the dose delivered by energetic particles to points deeper in the body.

Zeitlin, C.↗

Improving the Event Data Server of the Fermilab Test Beam Data Acquisition System (OTSDAQ)

The Fermilab Test Beam Facility (FTBF) is a high-energy test beam used for precision tests of high-energy physics detectors. The FTBF has two beams lines, MTest and MCenter, which provides a variety particle types such as proton beam and secondary beams with muons, electrons, and kaons. The beam is variable in energy and intensity, and a target can be inserted into the beam to convert the protons to other particle types for users.

43 PARTICLE ACCELERATORS↗

An Operationally Integrated Approach to the SNS 2.8 MW Power Upgrade

The SNS accelerator consist of a 1 GeV H⁻ linac and an accumulator ring producing a 1.4 MW pulsed proton beam which drives a spallation neutron source. The Proton Power Upgrade project will double the power capability from 1.4 to 2.8 MW by increasing the linac energy 30% and the beam current about 50%. Equipment upgrades include new superconducting RF cryomodules and supporting RF equipment, upgraded ring equipment, and upgraded high power target systems. An important aspect of the upgrade is a gradual power ramp-up starting in 2022 in which new equipment is installed during maintenance outages as it arrives.

Galambos, John D↗

Analysis and interpretation of the shocklike electrostatic noise observed during the AMPTE solar wind lithium releases

During the AMPTE (Active Magnetospheric Particle Tracer Explorers) solar wind lithium release on September 11, and again on September 20, 1984, an intense burst of electrostatic noise was observed near the upstream edge of the ion cloud. Comparisons with measurements by the IMP-6 and ISEE-1 spacecraft show that the spectrum and overall features of this noise are very similar to electrostatic noise observed at the Earth's bow shock. A stability analysis using realistic parameters shows that the electrostatic noise can be accounted for by an ion beam-plasma instability caused by the solar wind proton beam streaming through the nearly stationary lithium cloud. The growth rate of this instability is largest when the ion density and solar wind proton density are similar, which explains why the noise only occurs near the outer edge of the ion cloud. The similarity to the noise in the Earth's bow shock suggest that a shock may exist in the solar wind plasma flow upstream of the ion cloud. If the noise is associated with a shock, then it must be an electrostatic shock, since the ion cyclotron radii are too small for the existence of a MHD shock. Since the electrostatic instability occurs at phase velocities near the lithium thermal velocity, the electrostatic turbulence may play a role in heating the lithium ions and transferring momentum from the solar wind to the ion cloud.

Gurnett, D. A.↗

Proton Therapy in Supradiaphragmatic Lymphoma: Predicting Treatment-Related Mortality to Help Optimize Patient Selection

In some patients with Hodgkin lymphoma (HL), proton beam therapy (PBT) may reduce the risk of radiation-related cardiovascular disease (CVD) and second cancers (SC) compared with photon radiation therapy (RT). Our aim was to identify patients who benefit the most from PBT in terms of predicted 30-year absolute mortality risks (AMR{sub 30}) from CVD and SC, taking into account individual background, chemotherapy, radiation, and smoking-related risks.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Development of a Beam Sweeping System for the Fermilab Antiproton Source Target

Intensity of the incident 120-GeV proton beam on the antiproton production target is scheduled to increase to 5x10 12 protons per pulse. To prevent damage to the target, we plan to spread the hot spot on target with a beam sweeping system, Now under development are rotating-field magnets for installation upstream and downstream of the target. These magnets will deflect the beam in a circular pattern on the target. Peak current of 7 kA and peak voltage drop of 6 kV are expected. The power supply, which is separated from the magnet by a distance of about 10 m, utilizes magnetic pulse compression by saturating inductors to drive the magnets through the long transmission lines.

43 PARTICLE ACCELERATORS↗

Bent Crystal Channeling for Optimized Beam Shadowing and Proton Extraction at Mu2e

The Mu2e experiment is designed to investigate the CLFV through the observation of a neutrinoless muon-to-electron conversion in the field of an Al nucleus. The observation of such a process would be clear evidence of physics beyond the standard model. Due to the rarity of this process, a cutting-edge, intense muon beam is required to achieve an improvement of the current single-event sensitivity by 4 orders of magnitude. To achieve this goal, a primary proton beam with 8 GeV is extracted from the Fermilab Delivery Ring using the slow resonant extraction technique. Mu2e requires ~3.6x10$^{20}$ protons-on-target to meet its goal; hence, it is crucial to minimize the extraction losses. An important source of such losses are the particles impacting on the electrostatic septum blade. A very promising solution to the problem lies in the beam shadowing scheme tested at CERN SPS. In this approach, a bent crystal is strategically placed upstream of the septum, deflecting particles from the blade at a precise angle via the phenomenon of channeling. As a result, a zone with reduced particle flux is created downstream of the crystal, safeguarding the septum anode by minimizing interactions with the beam. This work explores the optimization of beam shadowing design and the process in the manufacturing and characterization of the bent crystal sample. It emphasizes the promising role of channeling in bent crystals, and it underscores the significant potential of channeling in bent crystals to assist the Mu2e experiment.

Fedeli, Pierluigi [Ferrara U.; INFN, Ferrara] (ORC↗

Search by the SENSEI Experiment for Millicharged Particles Produced in the NuMI Beam

Millicharged particles appear in several extensions of the standard model, but have not yet been detected. These hypothetical particles could be produced by an intense proton beam striking a fixed target. We use data collected in 2020 by the SENSEI experiment in the MINOS cavern at the Fermi National Accelerator Laboratory to search for ultrarelativistic millicharged particles produced in collisions of protons in the NuMI beam with a fixed graphite target. The absence of any ionization events with 3 to 6 electrons in the SENSEI data allow us to place world-leading constraints on millicharged particles for masses between 30 to 380 MeV. This work also demonstrates the potential of utilizing low-threshold detectors to investigate new particles in beam-dump experiments, and motivates a future experiment designed specifically for this purpose. Published by the American Physical Society 2024

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗