Search for Lepton-Flavor Violation in Z -Boson Decays with τ Leptons with the ATLAS Detector
Not Available
72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗
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Broadly cross-reactive human antibodies that inhibit genogroup I and II noroviruses
The rational development of norovirus vaccine candidates requires a deep understanding of the antigenic diversity and mechanisms of neutralization of the virus. Here, we isolate and characterize a panel of broadly cross-reactive naturally occurring human monoclonal IgMs, IgAs and IgGs reactive with human norovirus (HuNoV) genogroup I or II (GI or GII). We note three binding patterns and identify monoclonal antibodies (mAbs) that neutralize at least one GI or GII HuNoV strain when using a histo-blood group antigen (HBGA) blocking assay. The HBGA blocking assay and a virus neutralization assay using human intestinal enteroids reveal that the GII-specific mAb NORO-320, mediates HBGA blocking and neutralization of multiple GII genotypes. The Fab form of NORO-320 neutralizes GII.4 infection more potently than the mAb, however, does not block HBGA binding. The crystal structure of NORO-320 Fab in complex with GII.4 P-domain shows that the antibody recognizes a highly conserved region in the P-domain distant from the HBGA binding site. Dynamic light scattering analysis of GII.4 virus-like particles with mAb NORO-320 shows severe aggregation, suggesting neutralization is by steric hindrance caused by multivalent cross-linking. Aggregation was not observed with the Fab form of NORO-320, suggesting that this clone also has additional inhibitory features.
59 BASIC BIOLOGICAL SCIENCES↗
Verification of an energy-conserving semi-implicit electrostatic particle-in-cell scheme for modeling high-density plasma at scale
A verification study of a semi-implicit energy-conserving electrostatic particle-in-cell algorithm is presented. The algorithm relaxes the time-step and mesh-size constraints that require resolution of the plasma period and Debye length associated with traditional explicit momentum-conserving particle-in-cell algorithms. Physical implications and applicability of using the semi-implicit scheme for modeling high-density plasmas are discussed. Where possible, numerical results are compared against analytical solutions. The simulation results indicate that the algorithm is stable at time steps larger than twice the inverse plasma frequency and cell sizes larger than the Debye length. It is found that the algorithm gives adequate results, provided that the distribution function and the spatiotemporal scales dictating the physics of the problem are resolved. As such, the algorithm may provide a robust method for kinetic modeling of high-density plasmas at scale.
Cyclotron resonance↗
First neutral beam experiments on Wendelstein 7-X
In the previous divertor campaign, the Wendelstein 7-X (W7-X) device injected 3.6 MW of neutral beam heating power allowing for the achievement of densities approaching 2 × 10 20 m -3 , and providing the first initial assessment of fast ion confinement in a drift optimized stellarator. The neutral beam injection (NBI) system on W7-X is comprised of two beam boxes with space for four radio frequency sources each. The 3.6 MW of heating reported in this work was achieved with two sources in the NI21 beam box. The effect of combined electron-cyclotron resonance heating (ECRH) and NBI was explored through a series of discharges varying both NBI and ECRH power. Discharges without ECRH saw a linear increase in the line-integrated plasma density, and strong peaking of the core density, over the discharge duration. The presence of 1 MW of ECRH power was found to be sufficient to control a continuous density rise during NBI operation. Simulations of fast ion wall loads were found to be consistent with experimental infrared camera images during operation. In general, NBI discharges were free from the presence of fast ion induced Alfvénic activity, consistent with low beam betas. These experiments provide data for future scenario development and initial assessment of fast-ion confinement in W7-X, a key topic of the project.
70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
Virion glycosylation influences mycobacteriophage immune recognition
Glycosylation of eukaryotic virus particles is common and influences their uptake, trafficking, and immune recognition. In contrast, glycosylation of bacteriophage particles has not been reported; phage virions typically do not enter the cytoplasm upon infection, and they do not generally inhabit eukaryotic systems. We show here that several genomically distinct phages of Mycobacteria are modified with glycans attached to the C terminus of capsid and tail tube protein subunits. These O-linked glycans influence antibody production and recognition, shielding viral particles from antibody binding and reducing production of neutralizing antibodies. Glycosylation is mediated by phage-encoded glycosyltransferases, and genomic analysis suggests that they are relatively common among mycobacteriophages. Putative glycosyltransferases are also encoded by some Gordonia and Streptomyces phages, but there is little evidence of glycosylation among the broader phage population. The immune response to glycosylated phage virions in mice suggests that glycosylation may be an advantageous property for phage therapy of Mycobacterium infections.
59 BASIC BIOLOGICAL SCIENCES↗
Arsenite oxyanions affect CeO 2 nanoparticle dissolution and colloidal stability
While highly reactive cerium oxide nanoparticles (CeO 2 NPs) are widely used in industry, their transport in aquatic systems is not well understood. To fill this knowledge gap, the interactions of CeO 2 NPs with arsenite (As 3+ ), a toxic metalloid and potential co-present contaminant, were investigated with respect to CeO 2 NP colloidal stability, dissolution, and surface redox reactions. Arsenite showed distinctive effects at different concentrations, with a high As 3+ concentration (10 –4 M) inducing 90% of CeO 2 NPs to settle from solution after 8 hours, while lower As 3+ concentrations (10 –5 or 10 –6 M) led to only 20% of CeO 2 NPs settling. The dissolution of NPs was most significant in the 10 –5 M As 3+ system owing to a lesser extent of aggregation, exposing more CeO 2 surface for dissolution. In the three As 3+ concentration systems, >97% of aqueous arsenic remained as As 3+ over 6 hours. On the NP surface, adsorbed As III was oxidized to As V , resulting in 58–70% of the adsorbed arsenic remaining as As III . Simultaneously Ce IV was reduced to Ce III , increasing Ce III on the CeO 2 NP surface from 17% (without arsenite) to 21–25% (with arsenite). Further mechanistic analyses revealed that the adsorption of arsenite was the main contributor to neutralizing the CeO 2 NP surface potential, enhancing particle sedimentation. These findings suggest that the fate and transport of CeO 2 NPs in our experimental systems are strongly affected by arsenite concentration and its adsorption on NPs. Here, the results also highlight the importance of the interplay between NP aggregation, oxidation, and dissolution in predicting the behaviors of CeO 2 NPs and associated toxic elements in aquatic systems.
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
Isotope impact on Alfvén eigenmodes and fast ion transport in DIII-D
Abstract Measurements of beam driven Alfvén Eigenmode (AE) activity in matched deuterium (D) and hydrogen (H) DIII-D plasmas show a dramatic difference in unstable mode activity and fast ion transport for a given injected beam power. The dependence of the unstable AE spectrum in reversed magnetic shear plasmas on beam and thermal species is investigated in the current ramp by varying beam power in a sequence of discharges for fixed thermal and beam species at fixed density. In general, a spectrum of Reversed Shear Alfvén Eigenmodes (RSAEs) and Toroidal Alfvén Eigenmodes (TAEs) are driven unstable with sub-Alfvénic D beam injection while primarily only RSAEs are driven unstable for the H beam cases investigated. Further, for a given beam power, the driven AE amplitude is always reduced with H beams relative to D and for H thermal plasma relative to pure D or mixed D/H plasmas. Estimates of the fast ion stored energy combined with modeling using the hybrid kinetic-MHD code MEGA indicate that the dominant mechanism contributing to the difference between H and D beam drive is the faster classical slowing down of H beam ions relative to D and the resultant lower beam ion pressure. Calculations of the AE induced stored energy deficits using the reduced critical gradient model TGLFEP show quantitative agreement with the observed dependencies on injected power, isotope and minimum safety factor.
70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
Dispersive and absorptive C P violation in D 0 − D ¯ 0 mixing
Not Available
79 ASTRONOMY AND ASTROPHYSICS↗
Towards searches for heavy neutral leptons with the Short-Baseline Near Detector experiment
Heavy Neutral Leptons (HNLs) are hypothetical long-lived particles that extend the Standard Model and provide a natural explanation for the origin of neutrino masses, the generation of the baryon asymmetry through leptogenesis, and the nature of dark matter. The Short-Baseline Near Detector (SBND) is a 112-ton liquid argon time projection chamber located 110 m away from the Booster Neutrino Beam (BNB) target at Fermilab (Illinois, USA). The close location to the BNB origin makes the experiment sensitive to HNLs produced from meson decays in the beam. These heavy particles arrive at the detector later than neutrinos and decay into observable final states such as 𝜈e+e- or 𝜈π0, generating isolated electromagnetic showers. Thanks to SBND’s advanced scintillation light detection system, a timing resolution at the nanosecond level further boosts the experiment capabilities. In this poster, we present ongoing reconstruction efforts towards HNLs as well as expected sensitivities factoring in the reconstruction improvements.
Romeo Araujo, Jorge [Madrid, CIEMAT]↗
Search for long-lived particles decaying to a pair of muons in proton-proton collisions at $ \sqrt{s} $ = 13 TeV
An inclusive search for long-lived exotic particles decaying to a pair of muons is presented. The search uses data collected by the CMS experiment at the CERN LHC in proton-proton collisions at $ \sqrt{s} $ = 13 TeV in 2016 and 2018 and corresponding to an integrated luminosity of 97.6 fb$^{−1}$. The experimental signature is a pair of oppositely charged muons originating from a common secondary vertex spatially separated from the pp interaction point by distances ranging from several hundred μm to several meters. The results are interpreted in the frameworks of the hidden Abelian Higgs model, in which the Higgs boson decays to a pair of long-lived dark photons Z$_{D}$, and of a simplified model, in which long-lived particles are produced in decays of an exotic heavy neutral scalar boson. For the hidden Abelian Higgs model with m(Z$_{D}$) greater than 20 GeV and less than half the mass of the Higgs boson, they provide the best limits to date on the branching fraction of the Higgs boson to dark photons for cτ(Z$_{D}$) (varying with m(Z$_{D}$)) between 0.03 and ≈0.5 mm, and above ≈0.5 m. Our results also yield the best constraints on long-lived particles with masses larger than 10 GeV produced in decays of an exotic scalar boson heavier than the Higgs boson and decaying to a pair of muons.[graphic not available: see fulltext]
72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗
ORBIT simulations of fast ion power loads on the wall of the Divertor Tokamak Test
Abstract Neutral beam injection in tokamaks produces a population of fast ions, which interact with 3D magnetic fields in a variety of ways, often resulting in energetic particle losses in very short times to the wall. Careful design of neutral beams and active control of error fields helps to keep these losses to a minimum. Nevertheless, past experience in tokamaks in the 1980s and detailed simulations for future machines, such as International Thermonuclear Experimental Reactor, suggest that very localized fast ion losses (‘hot spots’) can be present, even if the overall losses are low. In this paper, we discuss this issue in the Divertor Tokamak Test (DTT) project, and we show that in the standard single-null full-power scenario of the DTT, fast ions produce two hot spots, corresponding approximately to the beam injection and exit toroidal angles: the former being mainly due to prompt losses/passing particles, while the latter is due to trapped ions. However, the maximum power load in these spots is of the order ∼ 63 kW m −2 , below the tolerance of plasma-facing components of the machine.
Physics↗
Overview of the results from divertor experiments with attached and detached plasmas at Wendelstein 7-X and their implications for steady-state operation
Abstract Wendelstein 7-X (W7-X), the largest advanced stellarator, is built to demonstrate high power, high performance quasi-continuous operation. Therefore, in the recent campaign, experiments were performed to prepare for long pulse operation, addressing three critical issues: the development of stable detachment, control of the heat and particle exhaust, and the impact of leading edges on plasma performance. The heat and particle exhaust in W7-X is realized with the help of an island divertor, which utilizes large magnetic islands at the plasma boundary. This concept shows very efficient heat flux spreading and favourable scaling with input power. Experiments performed to overload leading edges showed that the island divertor yields good impurity screening. A highlight of the recent campaign was a robust detachment scenario, which allowed reducing power loads even by a factor of ten. At the same time, neutral pressures at the pumping gap entrance yielded the particle removal rate close to the values required for stable density control in steady-state operation.
70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
Semi-inclusive direct photon + jet and 𝜋 0 + jet correlations measured in 𝑝 + 𝑝 and central Au + Au collisions at $\sqrt{s_{NN}}$ = 200GeV
The STAR experiment at RHIC reports new measurements of jet quenching based on the semi- inclusive distribution of charged-particle jets recoiling from direct photon (γ dir ) and neutral pion (π 0 ) triggers in pp and central Au + Au collisions at $\sqrt{s_{NN}}$ = 200 GeV, for triggers in the range 9 < $E$$^{trig}_{T}$ < 20 GeV. The datasets have integrated luminosities of 3.9nb −1 for Au + Au and 23pb −1 for 𝑝𝑝 collisions. Jets are reconstructed using the anti-𝑘 𝑇 algorithm with resolution parameters 𝑅 = 0.2 and 0.5. The large uncorrelated jet background in central Au + Au collisions is corrected using a mixed-event approach, which enables precise charged-particle jet measurements at low transverse momentum 𝑝$^{ch}_{𝑇,jet}$ and large 𝑅. Recoil-jet distributions are reported in the range 𝑝$^{ch}_{𝑇,jet}$ < 25 GeV/𝑐. Comparison of the distributions measured in 𝑝𝑝 and Au + Au collisions reveals strong medium-induced jet yield suppression for 𝑅 = 0.2 with markedly less suppression for 𝑅 = 0.5. Comparison is also made to theoretical models incorporating jet quenching. Furthermore, these data provide new insight into the mechanisms underlying jet quenching and the angular dependence of medium-induced jet-energy transport and provide new constraints on modeling such effects.
73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗
First evidence of dominant influence of E × B drifts on plasma cooling in an advanced slot divertor for tokamak power exhaust
Addressing power exhaust in tokamaks is presently recognized as one of the major remaining open issues for the development of fusion reactors. At the forefront of this endeavor is the effort to develop an advanced divertor by maximizing dissipation of plasma power and momentum inside the divertor. Here, we demonstrate, for the first time, that the electromagnetic (E × B) drifts exert a key influence on plasma and gas dynamics in a new advanced slot divertor in the DIII-D tokamak, named the small angle slot (SAS). SAS leverages the effect of drifts to achieve a highly dissipative divertor with electron temperature T e ≲ 10 eV over a wide range of plasma densities, for ion B × ∇B away from the divertor, as used for advanced tokamak operation on DIII-D. Modeling with the SOLPS-ITER code shows that for this drift direction, the E × B flow carries particles toward the outer common flux region (CFR) via the private flux region (PFR), reinforcing neutral recycling and enhancing divertor dissipation. In contrast, for the opposite field direction, the E × B flow carries particles away from the outer CFR into the PFR, offsetting the anticipated SAS geometric effects. Furthermore, this finding is an important step in the understanding of the behavior of advanced divertors for achieving a power exhaust solution for fusion reactors.
70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
Axionlike particles and sterile neutrinos solve the 𝐵 → 𝐾$𝜈\bar{𝜈}$ and 𝐵 → 𝜋𝐾 puzzles
The recent measurement of the branching ratio of 𝐵 + → 𝐾 + +inv (where “inv” denotes invisible states) by the Belle II Collaboration is enhanced relative to the standard model expectation by 2.7𝜎. An older puzzle persists in measurements of the branching ratios and 𝐶𝑃 asymmetries of 𝐵 → 𝜋𝐾 decays. We address these two anomalies in flavor-changing neutral current 𝐵 decays, with a short-lived axionlike particle (ALP) with mass close to that of the 𝜋 0 . In the model with the minimum number of new couplings, the ALP has couplings to the photon, top quark and a heavy sterile neutrino. The ALP contributes to the 𝐵 → 𝜋 0 𝐾 decays by mixing with the 𝜋 0 . It contributes to 𝐵 + → 𝐾 + + inv by its off-shell coupling to sterile neutrino pairs. The model can explain the excess in the total rate, but not the observed distribution of signal events. We make predictions for all 𝐵 → 𝐾 (*) + inv modes and for the rare kaon decays, 𝐾 + → 𝜋 + + inv and 𝐾 𝐿 → 𝜋 0 + inv. We find an appreciable contribution to the magnetic moment of the muon, and negligible contributions to the magnetic moment of the electron and 𝑏 → 𝑠𝑒 + 𝑒 − .
axion-like particles↗
Details of the neutral energy distribution and ionization source using spectrally resolved Balmer-alpha measurements on DIII-D
Spectrally resolved passive Balmer- α (D- α, H- α) measurements from the DIII-D 16 channel edge main-ion charge exchange recombination system confirm the presence of higher energy neutrals (“thermal” neutrals) in addition to the cold neutrals that recycle off the walls in the edge region of DIII-D plasmas. Charge exchange between thermal ions and edge neutrals transfers energy and momentum between the populations giving rise to thermal neutrals with energies approximating the ions in the pedestal region. Multiple charge exchange events in succession allow an electron to effectively take a random walk, transferring from ion to ion, providing a pathway of increasing energy and velocity, permitting a neutral to get deeper into the plasma before a final ionization event that contributes to the ion and electron particle fueling. Spectrally resolved measurements provide information about the density and velocity distribution of these neutrals, which has been historically valuable for validating Monte Carlo neutral models, which include the multi stage charge exchange dynamics. Here, in this study, a multi-channel set of such measurements is used to specifically isolate the details of the thermal neutrals that are responsible for fueling inside the pedestal top. Being able to separate the thermal from the cold emission overcomes several challenges associated with optical filter-based neutral density measurements. The neutral dynamics, deeper fueling by the thermal neutrals, and spectral measurement are modeled with the FIDASIM Monte Carlo collisional radiative code, which also produces synthetic spectra with a shape that is in close agreement with the measurements. By scaling the number of neutrals in the simulation to match the intensity of the thermal emission, we show it is possible to obtain local neutral densities and ionization source rates.
70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
Testing meson portal dark sector solutions to the MiniBooNE anomaly at the Coherent CAPTAIN Mills experiment
A solution to the MiniBooNE excess invoking rare three-body decays of the charged pions and kaons to new states in the MeV mass scale was recently proposed as a dark-sector explanation. This class of solution illuminates the fact that, while the charged pions were focused in the target-mode run, their decay products were isotropically suppressed in the beam-dump-mode run in which no excess was observed. This suggests a new physics solution correlated to the mesonic sector. We investigate an extended set of phenomenological models that can explain the MiniBooNE excess as a dark sector solution, utilizing long-lived particles that might be produced in the three-body decays of the charged mesons and the two-body anomalous decays of the neutral mesons. Over a broad set of interactions with the long-lived particles, we show that these scenarios can be compatible with constraints from LSND, KARMEN, and MicroBooNE, and evaluate the sensitivity of the ongoing and future data taken by the Coherent CAPTAIN Mills experiment to a potential discovery in this parameter space. Published by the American Physical Society 2024
72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗
Modeling fast ion losses due to tearing and internal kink perturbations in MAST-U
Fast ion (FI) loss properties in the presence of tearing mode and internal kink perturbations are numerically investigated for discharges in the MAST-U spherical tokamak, utilizing the MARS-F magnetohydrodynamic stability code and the REORBIT test particle guiding-center orbit-following module. Here, tracing about 100 000 particle markers sampled from the equilibrium distribution of the neutral-beam injection induced FIs, it is found that about 10% out of the total strike the limiting surface (including the divertor surface) in MAST-U discharge 46943, assuming a maximum perturbation of 100 G inside the plasma (corresponding to ~6 G at the Mirnov probe location at the outboard mid-plane). Detailed particle tracing, assuming a uniform initial distribution in the 2D phase space (at given radial locations), reveals that initially counter-current FIs launched near the plasma edge are subject to significant prompt losses, while almost all initially co-current ions remain well confined at the assumed perturbation level. Most lost FIs strike the lower-half of the limiting surface. Finite gyro-radius effects prevent lost ions from striking the top-outer corner of the super-X divertor chamber. A scan of the perturbation level (based on discharge 45163) reveals, not surprisingly, an approximately linear scaling of the particle loss fraction (for counter-current FIs) with respect to the perturbation amplitude.
70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗