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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 271 records · Page 15
All sourcesNASA NTRSDOE OSTI
DOE OSTI2022

A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program

The study aims to determine the shared genetic architecture between COVID-19 severity with existing medical conditions using electronic health record (EHR) data. We conducted a Phenome-Wide Association Study (PheWAS) of genetic variants associated with critical illness (n = 35) or hospitalization (n = 42) due to severe COVID-19 using genome-wide association summary data from the Host Genetics Initiative. PheWAS analysis was performed using genotype-phenotype data from the Veterans Affairs Million Veteran Program (MVP). Phenotypes were defined by International Classification of Diseases (ICD) codes mapped to clinically relevant groups using published PheWAS methods. Among 658,582 Veterans, variants associated with severe COVID-19 were tested for association across 1,559 phenotypes. Variants at the ABO locus (rs495828, rs505922) associated with the largest number of phenotypes (n rs495828 = 53 and n rs505922 = 59); strongest association with venous embolism, odds ratio (OR rs495828 1.33 (p = 1.32 x 10 –199 ), and thrombosis OR rs505922 1.33, p = 2.2 x10 -265 . Among 67 respiratory conditions tested, 11 had significant associations including MUC5B locus (rs35705950) with increased risk of idiopathic fibrosing alveolitis OR 2.83, p = 4.12 × 10 –191 ; CRHR1 (rs61667602) associated with reduced risk of pulmonary fibrosis, OR 0.84, p = 2.26× 10 –12 . The TYK2 locus (rs11085727) associated with reduced risk for autoimmune conditions, e.g., psoriasis OR 0.88, p = 6.48 x10 -23 , lupus OR 0.84, p = 3.97 x 10 –06 . PheWAS stratified by ancestry demonstrated differences in genotype-phenotype associations. LMNA (rs581342) associated with neutropenia OR 1.29 p = 4.1 x 10 –13 among Veterans of African and Hispanic ancestry but not European. Overall, we observed a shared genetic architecture between COVID-19 severity and conditions related to underlying risk factors for severe and poor COVID-19 outcomes. Differing associations between genotype-phenotype across ancestries may inform heterogenous outcomes observed with COVID-19. Divergent associations between risk for severe COVID-19 with autoimmune inflammatory conditions both respiratory and non-respiratory highlights the shared pathways and fine balance of immune host response and autoimmunity and caution required when considering treatment targets.

59 BASIC BIOLOGICAL SCIENCES↗
NASA NTRS2017

EVA Systems Technology Gaps and Priorities 2017

Performance of Extra-Vehicular Activities (EVA) has been and will continue to be a critical capability for human space flight. Human exploration missions beyond LEO will require EVA capability for either contingency or nominal activities to support mission objectives and reduce mission risk. EVA systems encompass a wide array of products across pressure suits, life support systems, EVA tools and unique spacecraft interface hardware (i.e. EVA Translation Paths and EVA Worksites). In a fiscally limited environment with evolving transportation and habitation options, it is paramount that the EVA community's strategic planning and architecture integration products be reviewed and vetted for traceability between the mission needs far into the future to the known technology and knowledge gaps to the current investments across EVA systems. To ascertain EVA technology and knowledge gaps many things need to be brought together, assessed and analyzed. This includes an understanding of the destination environments, various mission concept of operations, current state of the art of EVA systems, EVA operational lessons learned, and reference advanced capabilities. A combined assessment of these inputs should result in well-defined list of gaps. This list can then be prioritized depending on the mission need dates and time scale of the technology or knowledge gap closure plan. This paper will summarize the current state of EVA related technology and knowledge gaps derived from NASA's Exploration EVA Reference Architecture and Operations Concept products. By linking these products and articulating NASA's approach to strategic development for EVA across all credible destinations an EVA could be done in, the identification of these gaps is then used to illustrate the tactical and strategic planning for the EVA technology development portfolio. Finally, this paper illustrates the various "touch points" with other human exploration risk identification areas including human health and performance.

Johnson, Brian J.↗
NASA NTRS2018

Characterization of On-Orbit GPS Transmit Antenna Patterns for Space Users

The GPS Antenna Characterization Experiment (GPS ACE) has made extensive observations of GPS L1 signals received at geosynchronous (GEO) altitude, with the objective of developing comprehensive models of the signal levels and signal performance in the GPS transmit antenna side lobes. The experiment was originally motivated by the fact that data on the characteristics and performance of the GPS signals available in GEO and other high Earth orbits was limited. The lack of knowledge of the power and accuracy of the side lobe signals on-orbit added risk to missions seeking to employ the side lobes to meet navigation requirements or improve performance. The GPS ACE Project lled that knowledge gap through a collaboration between The Aerospace Corporation and NASA Goddard Space Fight Center to collect and analyze observations from GPS side lobe transmissions to a satellite at GEO using a highly-sensitive GPS receiver installed at the ground station. The GPS ACE architecture has been in place collecting observations of the GPS constellation with extreme sensitivity for several years. This sensitivity combined with around-the-clock, all-in-view processing enabled full azimuthal coverage of the GPS transmit gain patterns over time to angles beyond 90 degrees off-boresight. Results discussed in this paper include the reconstructed transmit gain patterns, with comparisons to available pre-fight gain measurements from the GPS vehicle contractors. For GPS blocks with extensive ground measurements, the GPS ACE results show remarkable agreement with ground based measurements. For blocks without extensive ground measurements, the GPS ACE results provide the only existing assessments of the full transmit gain patterns. The paper also includes results of pseudorange deviation analysis to assess systematic errors associated with GPS side lobe signals.

space↗
NASA NTRS2018

Characterization of On-Orbit GPS Transmit Antenna Patterns for Space Users

The GPS Antenna Characterization Experiment (GPS ACE) has made extensive observations of GPS L1 signals received at geosynchronous (GEO) altitude, with the objective of developing comprehensive models of the signal levels and signal performance in the GPS transmit antenna side lobes. The experiment was originally motivated by the fact that data on the characteristics and performance of the GPS signals available in GEO and other high Earth orbits was limited. The lack of knowledge of the power and accuracy of the side lobe signals on-orbit added risk to missions seeking to employ the side lobes to meet navigation requirements or improve performance. The GPS ACE Project lled that knowledge gap through a collaboration between The Aerospace Corporation and NASA Goddard Space Fight Center to collect and analyze observations from GPS side lobe transmissions to a satellite at GEO using a highly-sensitive GPS receiver installed at the ground station. The GPS ACE architecture has been in place collecting observations of the GPS constellation with extreme sensitivity for several years. This sensitivity combined with around-the-clock, all-in-view processing enabled full azimuthal coverage of the GPS transmit gain patterns over time to angles beyond 90 degrees o -boresight. Results discussed in this paper include the reconstructed transmit gain patterns, with comparisons to available pre-fight gain measurements from the GPS vehicle contractors. For GPS blocks with extensive ground measurements, the GPS ACE results show remarkable agreement with ground based measurements. For blocks without extensive ground measurements, the GPS ACE results provide the only existing assessments of the full transmit gain patterns. The paper also includes results of pseudorange deviation analysis to assess systematic errors associated with GPS side lobe signals.

Donaldson, Jennifer E.↗
NASA NTRS2020

Characterization of On-Orbit GPS Transmit Antenna Patterns for Space Users

The GPS Antenna Characterization Experiment (GPS ACE) has made extensive observations of GPS L1 signals received at geosynchronous (GEO) altitude, with the objective of developing comprehensive models of the signal levels and signal performance in the GPS transmit antenna side lobes. The experiment was originally motivated by the fact that data on the characteristics and performance of the GPS signals available in GEO and other high Earth orbits was limited. The lack of knowledge of the power and accuracy of the side lobe signals on-orbit added risk to missions seeking to employ the side lobes to meet navigation requirements or improve performance. The GPS ACE Project lled that knowledge gap through a collaboration between The Aerospace Corporation and NASA Goddard Space Fight Center to collect and analyze observations from GPS side lobe transmissions to a satellite at GEO using a highly-sensitive GPS receiver installed at the ground station. The GPS ACE architecture has been in place collecting observations of the GPS constellation with extreme sensitivity for several years. This sensitivity combined with around-the-clock, all-in-view processing enabled full azimuthal coverage of the GPS transmit gain patterns over time to angles beyond 90 degrees o -boresight. Results discussed in this paper include the reconstructed transmit gain patterns, with comparisons to available pre-fight gain measurements from the GPS vehicle contractors. For GPS blocks with extensive ground measurements, the GPS ACE results show remarkable agreement with ground based measurements. For blocks without extensive ground measurements, the GPS ACE results provide the only existing assessments of the full transmit gain patterns. The paper also includes results of pseudorange deviation analysis to assess systematic errors associated with GPS side lobe signals.

Jennifer E Donaldson↗
NASA NTRSDate not supplied

Adding a Verification View for Autonomous Real-Time Architecture

Spacecraft software systems continue to increase in complexity and must frequently operate autonomously for extended periods. Thus, the consequences of software flaws are increasing and it is necessary to improve development methods to minimize the risk of latent flaws in the operational software. Traditional software architectures place verification as one element in the development architectural view and treat verification as a later lifecycle activity that is considered complete when the system is certified for flight. The Gateway Vehicle System Manager team, recognizing the importance of verification throughout the system lifecycle, is treating verification as an additional architectural view that receives continuous attention from the requirements analysis phase and continuing for the life of the operational system. The verification view consists of two viewpoints: development and operational. We present background on the verification view and discuss the approaches the Vehicle System Manager team is taking.

James B Dabney↗
NASA NTRS2020

Parabolic Deformable Mirror Testbed for the ExoSpec Project

The ExoSpec Project is a NASA Headquarters directed work package that links four different tasks at Goddard Space Flight Center to enable future missions to more efficiently characterize directly imaged exoplanets. One of the tasks is the development of parabolic deformable mirrors to improve on the current state-of-the-art wavefront sensing and control implementations, which are baselined to have two flat deformable mirrors (DMs) with high actuator count. To effectively control both amplitude and phase aberrations, the flat DMs need to have a large separation, which poses packaging challenges to missions designed to image rocky exoplanets. To eliminate this large separation, the parabolic DM architecture makes the off-axis imaging elements in the optical train controllable. Simulations also show performance enhancements with the architecture change; larger bandwidths have been shown to be controllable with the parabolic DMs and the number of required actuators can be reduced. With a 32×32 pupil flat DM and two 16x16 parabolic DMs, we could obtain a 5 - 12λ/D dark hole at 35%bandwidth. In addition to addressing the packaging challenge faced by future coronagraph missions, reducing the number of actuators reduces both cost and risk of having the entire coronagraph instrument’s performance depend on two high-actuator count DMs. To test these simulations, Goddard is building a testbed and has a vendor developing the parabolic DM. Here we present these simulations, the current testbed performance, and the development plan to incorporate and test the parabolic DMs

Coronagraph↗
NASA NTRS2012

Composite Payload Fairing Structural Architecture Assessment and Selection

This paper provides a summary of the structural architecture assessments conducted and a recommendation for an affordable high performance composite structural concept to use on the next generation heavy-lift launch vehicle, the Space Launch System (SLS). The Structural Concepts Element of the Advanced Composites Technology (ACT) project and its follow on the Lightweight Spacecraft Structures and Materials (LSSM) project was tasked with evaluating a number of composite construction technologies for specific Ares V components: the Payload Shroud, the Interstage, and the Core Stage Intertank. Team studies strived to address the structural challenges, risks and needs for each of these vehicle components. Leveraging off of this work, the subsequent Composites for Exploration (CoEx) effort is focused on providing a composite structural concept to support the Payload Fairing for SLS. This paper documents the evaluation and down selection of composite construction technologies and evolution to the SLS Payload Fairing. Development of the evaluation criteria (also referred to as Figures of Merit or FOMs), their relative importance, and association to vehicle requirements are presented. A summary of the evaluation results, and a recommendation of the composite concept to baseline in the Composites for Exploration (CoEx) project is presented. The recommendation for the SLS Fairing is a Honeycomb Sandwich architecture based primarily on affordability and performance with two promising alternatives, Hat stiffened and Fiber Reinforced Foam (FRF) identified for eventual program block upgrade.

Krivanek, Thomas M.↗
NASA NTRS2006

Technology Development for Fire Safety in Exploration Spacecraft and Habitats

Fire during an exploration mission far from Earth is a particularly critical risk for exploration vehicles and habitats. The Fire Prevention, Detection, and Suppression (FPDS) project is part of the Exploration Technology Development Program (ETDP) and has the goal to enhance crew health and safety on exploration missions by reducing the likelihood of a fire, or, if one does occur, minimizing the risk to the mission, crew, or system. Within the past year, the FPDS project has been formalized within the ETDP structure and has seen significant progress on its tasks in fire prevention, detection, and suppression. As requirements for Constellation vehicles and, specifically, the CEV have developed, the need for the FPDS technologies has become more apparent and we continue to make strides to infuse them into the Constellation architecture. This paper describes the current structure of the project within the ETDP and summarizes the significant programmatic activities. Major technical accomplishments are identified as are activities planned for FY07.

Ruff, Gary A.↗
NASA NTRS2007

Technology Development for Fire Safety in Exploration Spacecraft and Habitats

Fire during an exploration mission far from Earth is a particularly critical risk for exploration vehicles and habitats. The Fire Prevention, Detection, and Suppression (FPDS) project is part of the Exploration Technology Development Program (ETDP) and has the goal to enhance crew health and safety on exploration missions by reducing the likelihood of a fire, or, if one does occur, minimizing the risk to the mission, crew, or system. Within the past year, the FPDS project has been formalized within the ETDP structure and has seen significant progress on its tasks in fire prevention, detection, and suppression. As requirements for Constellation vehicles and, specifically, the CEV have developed, the need for the FPDS technologies has become more apparent and we continue to make strides to infuse them into the Constellation architecture. This paper describes the current structure of the project within the ETDP and summarizes the significant programmatic activities. Major technical accomplishments are identified as are activities planned for FY07.

Ruff, Gary A.↗
NASA NTRS2019

Silver Foam as Long-Term Passive Biocide for Potable Water Systems

A spacecraft water disinfection system, suitable for extended length space exploration missions, should prevent or control the growth of microbes, prevent or limit biofilm formation, and prevent microbiologically-influenced corrosion. In addition, the system should have minimal maintenance requirements, the effluent should be chemically compatible with all materials in contact with the water, be safe for human consumption, and suitable to be shared across international spacecraft platforms and mission architectures. Silver ions are a proven broad spectrum biocide. Silver is also the potable water biocide of choice for future exploration missions. Currently, the proposed method for implementing silver biocide in spacecraft systems relies on silver electrode technology to produce a controlled amount of silver ions. Unfortunately, electrolytic-based silver dosing presents multiple inherent challenges that affect performance and increase maintenance requirements over time. To decrease the risk of failure, an alternative silver biocide delivery method is needed. Control-release technology is an attractive option for developing a passive high-reliability silver dosing device. The concept of a nanoparticle/polyurethane (PU) composite foam for the controlled release of silver was prompted by the controlled release technology developed by NASA for the delivery of corrosion inhibitors and indicators. This paper presents the technical background and results from the synthesis and properties testing of the silver nanoparticles (AgNPs)/PU composite foam that is being developed for use in spacecraft potable water systems.

Irwin, Tesia D.↗
NASA NTRSDate not supplied

Precision Synchronization for Free-Space Quantum Networking

Precision synchronization is vital for robust long-distance quantum networking over fiber and free-space channels for which high-fidelity entanglement swapping between separate sources via an optical Bell state measurement requires temporal overlap of photonic qubits arriving from either source. This challenge is particularly distinct in satellite-based entanglement distribution in which relative motion, channel effects, and propagation delay must be addressed. This work presents a precision synchronization method for free space entanglement distribution, and reports on risk reduction testing in a quantum networking testbed at MIT Lincoln Laboratory. Primary consideration is for a dual-uplink architecture in which photons from entanglement sources at two ground locations interact in an optical Bell-state measurement implemented on a satellite in a low-earth orbit. The control approach uses independent entanglement sources at each ground location supplemented with a synchronization signal for feedback control from a timing discriminant measured at the spacecraft. The approach is being implemented in a laboratory testbed using 1-GHz repetition rate 1550-nm band entanglement sources generating ~10-MHz source entanglement rates with few-ps photon pulse lengths. The paper describes both fundamental architectural considerations and practical implementation details.

quantum↗
NASA NTRS2007

Designing for Our Future in Space

Over the past several years, the disciplines of architecture and human factors have been increasingly recognized as specialties that have focused upon "human-centered design" in the development of spacecraft and surface habitats. These specialties have been instrumental in the conceptual design of overall spacecraft configurations and layouts, as well as habitability outfitting hardware, such as the galley, hygiene facility, sleep quarters, or the layout of displays and controls. From the human-centered perspective, this approach to design assists in the mitigation of risk when designing for an extreme environment such as space. It takes into account the human s physical and cognitive capabilities and limitations, the human s performance in the context of human space flight, the human s interaction with machines that are both physically and cognitively complex, the activities required of the human to accomplish the goals of missions, and the use of design practices that promote products to enable human activity. It is this latter aspect - the use of design practices that promote products to enable human activity - that is the focus of the approach used by the Rhode Island School of Design (RISD) in collaboration with the Habitability and Human Factors Branch (HHFB) at the NASA Johnson Space Center (JSC). During the past few years, there has been a growing recognition of the value added by utilizing industrial designers to further the conceptual development of space hardware, that when used in conjunction with architecture and human factors, provides a robust solution to the design challenge. The "Design for Extreme Environments" Studio at RISD has taken suggested design topics from the NASA JSC HHFB and asked the students to investigate solutions to these challenges. The topics have demanded that the student pay particular attention to a variety of aspects of the space environment and understand how the human responds to each. The student must then adapt the design to these responses. The studio environment has been one way to introduce these challenges, but providing for an "in-residence" opportunity at JSC has given the students a broader vision and set of experiences. The accompanying presentation highlights the studio as well as in-residence work that has been accomplished.

Connolly, Janis↗
NASA NTRS2003

Optimizing spacecraft design - optimization engine development : progress and plans

At JPL and NASA, a process has been developed to perform life cycle risk management. This process requires users to identify: goals and objectives to be achieved (and their relative priorities), the various risks to achieving those goals and objectives, and options for risk mitigation (prevention, detection ahead of time, and alleviation). Risks are broadly defined to include the risk of failing to design a system with adequate performance, compatibility and robustness in addition to more traditional implementation and operational risks. The options for mitigating these different kinds of risks can include architectural and design choices, technology plans and technology back-up options, test-bed and simulation options, engineering models and hardware/software development techniques and other more traditional risk reduction techniques.

risk↗
NASA NTRS2016

Technology Overview and Assessment for Small-Scale EDL Systems

Motivated by missions to land large rovers and humans at Mars and other bodies, high-mass EDL technologies are a prevalent trend in the research community. In contrast, EDL systems for low-mass payloads have attracted less attention. Significant potential in science and discovery exists in small-scale EDL systems. Payloads acting secondary to a flagship mission are a currently under-utilzed resource. Before taking advantage of these opportunities, further developed of scaled EDL technologies is required. The key limitations identified in this study are compact decelerators and deformable impact systems. Current technologies may enable rough landing of small payloads, with moderate restrictions in packaging volume. Utilization of passive descent and landing stages will greatly increase the applicability of small systems, allowing for vehicles robust to entry environment uncertainties. These architectures will provide an efficient means of achieving science and support objectives while reducing cost and risk margins of a parent mission.

small spacecraft↗
NASA NTRS2017

The Impact of Mission Duration on a Mars Orbital Mission

Performance alone is insufficient to assess the total impact of changing mission parameters on a space mission concept, architecture, or campaign; the benefit, cost, and risk must also be understood. This paper examines the impact to benefit, cost, and risk of changing the total mission duration of a human Mars orbital mission. The changes in the sizing of the crew habitat, including consumables and spares, was assessed as a function of duration, including trades of different life support strategies; this was used to assess the impact on transportation system requirements. The impact to benefit is minimal, while the impact on cost is dominated by the increases in transportation costs to achieve shorter total durations. The risk is expected to be reduced by decreasing total mission duration; however, large uncertainty exists around the magnitude of that reduction.

Arney, Dale↗
DOE OSTI2026

Virtual Power Plant Architecture and Resilient Design

Virtual Power Plants (VPPs) represent a fundamental shift in electric grid operations, aggregating distributed energy resources (DERs) such as solar panels and battery storage to deliver utility-scale grid services traditionally provided by centralized power plants. This report examines the unique architectural, operational, and digital assurance considerations that distinguish VPPs from conventional utility infrastructure as they scale from pilot projects to mainstream deployment across the United States. While VPPs offer significant opportunities for grid modernization and enhanced flexibility, their distributed, multi-stakeholder architecture introduces distinct security challenges that differ fundamentally from traditional generation facilities. The analysis identifies risks in VPP operations, including device-level security gaps, platform vulnerabilities, and communication protocol weaknesses that create expanded attack surfaces compared to centralized power plants. Through examination of real-world incidents and emerging threat patterns, the report demonstrates how some VPPs' reliance on consumer-owned devices, public internet infrastructure, and complex vendor ecosystems require new approaches to digital assurance and operational security. The findings provide practical guidance for utilities, regulators, and aggregators to implement robust security frameworks and operational best practices essential for maintaining grid reliability as VPP deployment accelerates under the Federal Energy Regulatory Commission (FERC) Order 2222 and related regulatory initiatives.

24 - POWER TRANSMISSION AND DISTRIBUTION↗
NASA NTRSDate not supplied

Design Considerations for Aerocapture Delivery of Uranus Orbiter and Probe

This paper presents an aerocapture system design for delivering the Uranus Orbiter and Probe (UOP) subsystems to their science orbit using the Mars Science Laboratory architecture. A packaging and integration scheme are presented for UOP subsystems, with careful consideration of large components required for outer planet science missions (RTG power generation, RF communications). The implication of packaging multiple RTG’s inside an aeroshell during a multiple year cruise phase will be explained, with possible thermal design solutions to mitigate RTG waste heat analyzed. Mass properties and margins for the system are discussed and an overall mass risk assessment is presented for the entry system and total flight system at launch. Alternative vehicle configurations are explored to include multiple probes and enable science objectives during transit to Uranus. Aerocapture mass savings when compared to the baseline UOP design are presented.

Andrew J. Gomez-Delrio↗