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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 289 records · Page 16
All sourcesNASA NTRSDOE OSTI
NASA NTRS2002

Effects of rotation on the sleep state-dependent midlatency auditory evoked P50 potential in the human

Sopite syndrome, characterized by loss of initiative, sensitivity to normally innocuous sensory stimuli, and impaired concentration amounting to a sensory gating deficit, is commonly associated with Space Motion Sickness (SMS). The amplitude of the P50 potential is a measure of level of arousal, and a paired-stimulus paradigm can be used to measure sensory gating. We used the rotary chair to elicit the sensory mismatch that occurs with SMS by overstimulating the vestibular apparatus. The effects of rotation on the manifestation of the P50 midlatency auditory evoked response were then assessed as a measure of arousal and distractibility. Results showed that rotation-induced motion sickness produced no change in the level of arousal but did produce a significant deficit in sensory gating, indicating that some of the attentional and cognitive deficits observed with SMS may be due to distractibility induced by decreased habituation to repetitive stimuli.

Clinical Trial↗
NASA NTRS2012

The Reawakening of the Sleeping X-ray Pulsar XTE J1946+274

We report on a series of outbursts of the high mass X-ray binary XTE 11946+274 in 2010/2011 as observed with INTEGRAL, RXTE, and Swift. We discuss possible mechanisms resulting in the extraordinary outburst behavior of this source. The X-ray spectra can be described by standard phenomenological models, enhanced by an absorption feature of unknown origin at about 10 keV and a narrow iron K alpha fluorescence line at 6.4keV, which are variable in flux and pulse phase. We find possible evidence for the presence of a cyclotron resonance scattering feature at about 25 keV at the 93% level. The presence of a strong cyclotron line at 35 keV seen in data from the source's 1998 outburst and confirmed by a reanalysis of these data can be excluded. This result indicates that the cyclotron line feature in XTE 11946+274 is variable between individual outbursts.

Mueller, Sebastian↗
NASA NTRS2015

LEDs Illuminate Bulbs for Better Sleep, Wake Cycles

Life on the International Space Station (ISS) wreaks havoc on an astronaut’s biological rhythms, and one way NASA mitigates the problem is through the use of LED lighting to alternately stimulate energy and focus and induce relaxation. Satellite Beach, Florida-based Lighting Science partnered with Kennedy Space Center to commercialize an LED system designed for the ISS, resulting in its DefinityDigital product line of light bulbs now used in numerous homes, hotel chains, and resorts.

Source record↗
NASA NTRSDate not supplied

Comparison Between Continuous and Intermittent Actigraphy Outcomes During Long-Duration Missions

INTRODUCTION Historically, astronauts have worn actigraphy watches continuously throughout their missions. This has enabled reliable sleep estimation and comparisons between sleep and other outcomes and mission activities such as the arrival of a visiting vehicle. However in late 2020, astronauts were scheduled to wear an actiwatch for one 2-week period every two months, substantially decreasing availability of data. Our aim was to compare sleep and mission events between data collected continuously and data collected intermittently to identify any differences. METHODS Crewmembers (n = 19) who volunteered for the NASA Standard Measures protocol between January 2019 and March 2022 were provided with actiwatches (Phillips, Respironics, Bend OR) that they wore either continuously (C; n = 9) or for two weeks every two months while in space (2W; n = 10). We used crew schedules to identify mission events that were asynchronous with actigraphy. We further compared sleep outcomes (sleep duration, wake after sleep onset [WASO], sleep efficiency) between the C and 2W actigraphy collection. RESULTS In the 2W group, sleep data was not available for 52% of EVAs, 67% of visiting vehicle events, and 67% of commander turnovers. Average sleep duration for the 2W group (M = 6.91, ± 1.24 SD) was significantly lower compared to the C group (7.51 ± 1.08, p < .01). Sleep efficiency was better for those in the C group (90.56 ± 5.19) than for those in the 2W group (87.02 ± 6.47 p < .01). There were no significant differences in WASO (C = 26.66 ±12.99; 2W = 32.38 ± 18.83). DISCUSSION Continuous actigraphy data collection yields different sleep outcomes compared to intermittent data collection. In addition, many mission events were not captured with intermittent data collection. Our findings support the use of continuous actigraphy data collection.

fatigue↗
NASA NTRS2011

Identification of Cardiometabolic Vulnerabilities Caused by Effects of Synergistic Stressors that are Commonly Encountered During Space Missions

Microgravity is a physiologically challenging state even when at rest. Astronauts experience additional physical and mental stresses, such as prolonged exertion, sleep loss and circadian misalignment, that could impact cardiovascular function. The main goals of this four year NASA project are to characterize the independent and synergistic effects on cardiovascular and immune function of: (1) circadian misalignment; (2) sleep loss; and (3) varied physical and mental stressors, mimicking some of the synergistic stressors experienced by astronauts. Sixteen healthy volunteers, aged 35-55 years, will be studied with standardized behavioral stressors occurring across all circadian phases, both with and without accruing sleep loss, achieved via two 11-day "forced desynchrony" protocols performed in each subject (randomized, within-subject design), where wake periods are advanced 4-h each "day" (i.e. recurring 20-h "days"). One protocol permits 8.33 h sleep opportunity per 20-h "day" (=10 h sleep per 24-h), and the other permits 5 h sleep per 20-h "day" (=6 h sleep per 24-h; matching the reported sleep duration of astronauts). In both protocols, subjects will perform a standardized stress battery including a cognitively challenging task; bicycle exercise, and passive 60deg head up tilt. Outcome variables include blood pressure, heart rate, arrhythmia frequency, cardiac vagal tone (from heart rate variability), sympathetic activity (catecholamines), and endothelial function. Additional measures of cardiac function (echocardiography), responses to a passive 80deg head up tilt, maximal oxygen uptake, and immune function will be assessed at the beginning and at the end of each protocol (i.e., without and with sleep loss, and before and after circadian misalignment). We hope to identify the relative impact on cardiovascular risk markers of varied behavioural stressors while subjects experience circadian misalignment and sleep loss, mimicking some of the synergistic stressors experienced by astronauts. Supported by NASANNX1 OAR 1 OG.

Ruger, M.↗
NASA NTRS2014

Fatigue in U.S. Astronauts Onboard the International Space Station: Environmental Factors, Operational Impacts, and Implementation of Countermeasures

Since 2000, US astronauts have been supporting missions up to a six month duration on the International Space Station (ISS). Crewmembers have experienced fatigue for reasons similar to military deployments. Astronauts experience psychological stressors such as heavy workloads, extended duty periods, circadian misalignment, inadequate/ineffective sleep, and loss of the environmental cues of a gravity environment. Complicating the psychological stressors are environmental factors; distracting background noise, unexpected and variable mission schedules, unfavorable thermal control, elevated CO2 levels, and an unusual sleep environment with schedules that impinge on pre‐sleep periods. Physiological contributors to poor sleep and fatigue include a cephalad fluid shift and back pain. Restful sleep is further challenged due to a lack of gravity‐related proprioceptive cues and need for restraints. The term "space fog" has been used by astronauts to describe a phenomenon of forgetfulness, slowed reaction time and transient confusion while trying to complete tasks. There is a distinct temporal correlation with arrival on the Space Station and the onset of slowed cognitive skills and a spontaneous resolution that may take up to 6 weeks. The Genesis of this phenomenon may be chronic fatigue secondary to transitioning from a planar environment to a 360deg microgravity perspective. Recently, countermeasures to improve sleep duration and quality in astronauts on the ISS have been instituted with moderate degrees of success as measured by self‐reaction time (psychomotor vigilance task testing), actigraphy, and subjective reports. Judicious use of stimulants and hypnotics, light therapy, controlled sleep periods and sleep shifting and reducing ambient CO2 levels are a few of the most promising countermeasures being used in space to improve sleep and reduce fatigue.

Scheuring, R. A.↗
NASA NTRS2019

Fatigue and Fatigue Countermeasures

Sleep can play an important role in alleviating health disparities, as inadequate sleep is associated with serious, adverse health conditions including cardiovascular disease, diabetes, obesity, cancer, and premature mortality. Nonetheless, dissemination of sleep health interventions targeted towards health disparities populations remains limited. Social workers and social work students serve populations designated as health disparities populations and are in an optimal position to promote sleep health among their underserved clients. However, social work students lack the specific training and resources necessary to promote healthy sleep practices among their clients. In fact, bachelors, master's, and doctoral social work programs in the United States do not incorporate any sleep health training as part of their curriculum. To improve public health through the promotion of healthy sleep practices among underserved populations, we propose to equip social work students, through an online learning module, with the knowledge and resources necessary to promote healthy sleep practices among their clients in underserved communities. In order to maximize effectiveness and reach, this proposal employs: (1) a collaborative team of sleep medicine and social work professionals; and (2) an ideal university environment with sophisticated eLearning capabilities that has one of the largest social work programs in the state of Florida.

fatigue countermeasure↗