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At least 289 records · Page 16

Assessing Reliability of NDE Flaw Detection Using Smaller Number of Demonstration Data Points

The paper provides an engineering analysis approach for assessing reliability of NDE flaw detection using smaller number of demonstration data points. It explores dependence of probability of detection (POD), probability of false positive (POF), on contrast-to-noise ratio, and net decision threshold-to-noise ratio in a simulated data; and draws some generically applicable inferences to devise the approach. ASTM nondestructive evaluation standards provide requirements on signal-to-noise ratio and/or contrast-to-noise ratio in order to provide reliable flaw detection and limit false positive calls. POD analysis of inspection test data results in an estimated flaw size, denoted by 𝑎90/95. This flaw size has 90% POD and minimum 95% confidence. POF is also estimated in the analysis. POD demonstration requires specimens with flaws of known size. In many situations, it is very expensive to produce the large number of flaws required for the POD analysis. In some situations, only real flaws can truly represent the flaws for demonstration. Real flaws of correct size and location in part configuration specimen may be difficult to produce, if not impossible. Here, an engineering analysis approach is devised using simulation to assess reliability of NDE technique when a limited number of flaws are available for demonstration. In this simulation, a technique is considered reliable, if it provides flaw detectability size equal to or better than the theoretical 𝑎90𝑡ℎ used in simulation and also provides a POF less than or equal to a chosen value. The paper uses simulated signal response versus flaw size data to devise the approach. Linear correlation is used between the signal response data and flaw size. POD software mh1823 uses generalized linear model (GLM) in POD analysis after transforming the flaw size and signal response, if needed, using logarithm. Therefore, this approach is in agreement with the linear signal correlation used in mh1823. Using the POD analysis of data, generic conditions on contrast-to-noise ratio and net decision threshold-to-noise ratio are derived for reliable flaw detection. In order to assess technique reliability using the engineering approach, signal response-to-flaw size correlation about the flaw size of concern is needed. In addition, measurement of noise is also needed. If the technique meets the above requirements, assumption of linear signal-to-flaw size correlation and conditions on noise, then the technique can be assessed using this analysis as it fits the underlying POD model used here. The approach is conservative and is designed to provide a larger flaw size compared to the POD approach. Such NDE technique assessment approach, although, not as rigorous as POD, can be cost effective if the larger flaw size can be tolerated. Typically, this is a situation for all quality control NDE inspections. Here, an NDE technique needs to be reliable and 𝑎90/95 is not estimated, but the assessed flaw size is assumed to be larger than the unknown a90 due to conservative factors or margins. Applicability of the approach for assessing reliability of flaw detection in x-ray radiography and 2D imaging in general is also explored.

Koshti, Ajay M.↗

Linking Asteroid Detections from the Large Synoptic Survey Telescope

We have conducted a detailed simulation of the Large Synoptic Survey Telescope (LSST) in order to understand the system’s ability to link detections of asteroids within and across nights in order to populate a catalog of asteroid orbits. We show that LSST, using its baseline survey cadence, should be able to successfully link and catalog asteroids. In our simulation of a single monthly observing cycle, LSST produced 66 million candidate detections of main belt asteroids (MBAs) and near Earth objects (NEOs), of which 77% were spurious detections related to detector noise or image processing. Using the Moving Object Processing System, we were able to assemble single-night “tracklets” with negligible losses, but a purity of only 43%. The next stage of linking led to three-night orbits with data sets no more than 12 days in length, and it is at this stage that the false detections are readily removed from the data stream. Main-belt linkages were essentially complete and 99.8% pure. Similarly, only 0.02% of linked detections involving NEOs were spurious. On the other hand, NEO linking was 93.6% complete, indicating that 6.4% of potentially findable NEOs were not successfully linked. We believe that this rate can be improved with careful tuning of the MOPS linking algorithms. The NEO catalog was affected by main-belt confusion so that mis-linked MBAs appeared as NEOs, and many correctly linked MBAs were consistent with NEO orbits. We show that these cases arise primarily from MBAs detected at lower solar elongations and we postulate that this is an artifact of a one month simulation that will be readily resolved by surveying over many months.

Chesley, Steven R.↗

Machine Learning-Based Atmospheric Phenomena Detection Platform

As the number of Earth pointing satellites has increased over the last several decades, the data volume retrieved from instruments onboard these satellites has also increased. It is expected that this trend will continue as more data intensive missions and small satellite constellations are launched. Currently, feature detection - namely atmospheric phenomena - in these datasets is performed manually and is thus not scalable with the growing data archives. Recent advancements in computational efficiency allow for the Earth science community to leverage machine learning to identify interesting atmospheric phenomena. Given the wide range of distinctive features in various atmospheric phenomena, a specialized machine learning model is required for accurate detection of these phenomena independently. The Phenomena Portal, developed at NASA IMPACT, is designed to provide visualization for the output from these machine learning models. In addition, detected events for each atmospheric phenomena are stored in a database that can be used to more easily use/subset larger spatiotemporal datasets. The user interface also incorporates additional features to enhance the user experience including spatiotemporal analysis, multiple base layer images, and a slider to filter events with lower probabilities of positive detection. Each detection supports user feedback on whether the detection is true or false that can then be stored and used to improve the machine learning model performance.

Gurung, Iksha↗

Improving Rain/No-Rain Detection Skill by Merging Precipitation Estimates from Different Sources

Rain/no-rain detection error is a key source of uncertainty in regional and global precipitation products that propagates into offline hydrological and land surface modeling simulations. Such detection error is difficult to evaluate and/or filter without access to high-quality reference precipitation datasets. For cases where such access is not available, this study proposes a novel approach for improved rain/no-rain detection. Based on categorical triple collocation (CTC) and a probabilistic framework, a weighted merging algorithm (CTC-M) is developed to combine noisy, but independent, precipitation products into an optimal binary rain/no-rain time series. Compared with commonly used approaches that directly apply the best parent product for rain/no-rain detection, the superiority of CTC-M is demonstrated analytically and numerically using spatially dense precipitation measurements over Europe. Our analysis also suggests that CTC-M is tolerant to a range of cross-correlated rain/no-rain detection errors and detection biases of the parent products. As a result, CTC-M will benefit global precipitation estimation by improving the representation of precipitation occurrence in gauge-based and multisource merged precipitation products.

Jianzhi Dong↗

Detecting water hazards for autonomous off-road navigation

Detecting water hazards for autonomous, off-road navigation of unmanned ground vehicles is a largely unexplored problem. In this paper, we catalog environmental variables that affect the difficulty of this problem, including day vs. night operation, whether the water reflects sky or other terrain features, the size of the water body, and other factors. We briefly survey sensors that are applicable to detecting water hazards in each of these conditions. We then present analyses and results for water detection for four specific sensor cases: 1) using color image classification to recognize sky reflections in water during the day, 2) using ladar to detect the presence of water bodies and to measure their depth, 3) using short-wave infrared (SWIR) imagery to detect water bodies, as well as snow and ice, and 4) using mid-wave infrared (MWIR) imagery to recognize water bodies at night. For color imagery, we demonstrate solid results with a classifier that runs at nearly video rate on a 433 MHz processor. For ladar, we present a detailed propagation analysis that shows the limits of water body detection and depth estimation as a function of look ahead distance, water depth, and ladar wavelength. For SWIR and MWIR, we present sample imagery from a variety of data collections that illustrate the potential of these sensors. These results demonstrate significant progress on this problem.

McHenry, Mike↗

Evaluation of the MODIS Collection 6 Multilayer Cloud Detection Algorithm Through Comparisons with Cloudsat Cloud Profiling Radar and CALIPSO CALIOP Products

Since multilayer cloud scenes are common in the atmosphere and can be an important source of uncertainty in passive satellite sensor cloud retrievals, the MODIS MOD06 and MYD06 standard cloud optical property products include a multilayer cloud detection algorithm to assist with data quality assessment. This paper presents an evaluation of the Aqua MODIS MYD06 Collection 6 multilayer cloud detection algorithm through comparisons with active Cloud Profiling Radar (CPR) and Cloud-Aerosol Lidar with Orthogonal Polarization (CALIOP) products that have the ability to provide cloud vertical distributions and directly classify multilayer cloud scenes and layer properties. To compare active sensor products with an imager such as MODIS, it is first necessary to define multilayer clouds in the context of their radiative impact on cloud retrievals. Three main parameters have thus been considered in this evaluation: (1) the maximum separation distance between two cloud layers, (2) the thermodynamic phase of those layers and (3) the upper-layer cloud optical thickness. The impact of including the Pavolonis–Heidinger multilayer cloud detection algorithm, introduced in Collection 6, to assist with multilayer cloud detection has also been assessed. For the year 2008, the MYD06 C6 multilayer cloud detection algorithm identifies roughly 20% of all cloudy pixels as multilayer (decreasing to about 13% if the Pavolonis–Heidinger algorithm output is not used). Evaluation against the merged CPR and CALIOP2B-CLDCLASS-lidar product shows that the MODIS multilayer detection results are quite sensitive to how multilayer clouds are defined in the radar and lidar product and that the algorithm performs better when the optical thickness of the upper cloud layer is greater than about 1.2 with a minimum layer separation distance of 1 km. Finally, we find that filtering the MYD06 cloud optical properties retrievals using the multilayer cloud flag improves aggregated statistics, particularly for ice cloud effective radius.

MODIS↗

An Overview of ARTMIP’s Tier 2 Reanalysis Intercomparison: Uncertainty in the Detection of Atmospheric Rivers and their Associated Precipitation

Atmospheric rivers, or long but narrow regions of enhanced water vapor transport, are an important component of the hydrologic cycle as they are responsible for much of the poleward transport of water vapor and result in precipitation, sometimes extreme in intensity. Despite their importance, much uncertainty remains in the detection of atmospheric rivers in large datasets such as reanalyses and century scale climate simulations. To understand this uncertainty, the Atmospheric River Tracking Method Intercomparison Project (ARTMIP) developed tiered experiments, including the Tier 2 Reanalysis Intercomparison that is presented here. Eleven detection algorithms submitted hourly tags--binary fields indicating the presence or absence of atmospheric rivers--of detected atmospheric rivers in the Modern Era Retrospective Analysis for Research and Applications, version 2 (MERRA-2) and European Centre for Medium-Range Weather Forecasts' Reanalysis Version 5 (ERA5) as well as six-hourly tags in the Japanese 55-year Reanalysis (JRA-55). Due to a higher climatological mean for integrated water vapor transport in MERRA-2, atmospheric rivers were detected more frequently relative to the other two reanalyses, particularly in algorithms that use a fixed threshold for water vapor transport. The finer horizontal resolution of ERA5 resulted in narrower atmospheric rivers and an ability to detect atmospheric rivers along resolved coastlines. The fraction of hemispheric area covered by ARs varies throughout the year in all three reanalyses, with different atmospheric river detection tools having different seasonal cycles.

ARTMIP↗

Automatic Detection of Large-scale Flux Ropes and Their Geoeffectiveness with a Machine-learning Approach

Detecting large-scale flux ropes (FRs) embedded in interplanetary coronal mass ejections (ICMEs) and assessing their geoeffectiveness are essential, since they can drive severe space weather. At 1 au, these FRs have an average duration of 1 day. Their most common magnetic features are large, smoothly rotating magnetic fields. Their manual detection has become a relatively common practice over decades, although visual detection can be time-consuming and subject to observer bias. Our study proposes a pipeline that utilizes two supervised binary classification machine-learning models trained with solar wind magnetic properties to automatically detect large-scale FRs and additionally determine their geoeffectiveness. The first model is used to generate a list of autodetected FRs. Using the properties of the southward magnetic field, the second model determines the geoeffectiveness of FRs. Our method identifies 88.6% and 80% of large-scale ICMEs (duration 1day) observed at 1au by the Wind and the Solar TErrestrial RElations Observatory missions, respectively. While testing with continuous solar wind data obtained from Wind, our pipeline detected 56 of the 64 large-scale ICMEs during the 2008–2014 period (recall = 0.875), but also many false positives (precision = 0.56), as we do not take into account any additional solar wind properties other than the magnetic properties. We find an accuracy of 0.88 when estimating the geoeffectiveness of the autodetected FRs using our method. Thus, in space-weather nowcasting and forecasting at L1 or any planetary missions, our pipeline can be utilized to offer a first-order detection of large-scale FRs and their geoeffectiveness.

Sanchita Pal↗

Detectability Simulations of a Near-infrared Surface Biosignature on Proxima Centauri b with Future Space Observatories

Telescope missions are currently being designed that will make direct imaging of habitable exoplanets possible in the near future, and studies are needed to quantify the detectability of biosignature features in the planet's reflectance spectrum. We simulated the detectability of a near-infrared-absorbing surface biosignature feature with simulated observations of the nearby exoplanet Proxima Centauri b. We modeled a biosignature spectral feature with a reflectance spectrum based on an anoxygenic photosynthetic bacterial species that has strong absorption at 1 μm, which could make it well suited for life on an M-dwarf-hosted planet. We modeled the distribution of this organism across the planet's surface based on climate states from a 3D general circulation model (GCM) that were Archean- and Proterozoic-like exo-Earth analogs. We included the GCM states' prognostically simulated water clouds and added organic haze into the Archean-like atmospheres. We simulated observations of these Proxima Centauri b scenarios with the LUVOIR-A and B telescope concepts, with LUVOIR-B serving as a proxy to the planned Habitable Worlds Observatory. We calculated the integration times necessary to detect the biosignature and found that it would be detectable on Proxima Centauri b if the organism is moderately abundant (greater than a 1%–4% global surface area coverage), as long as the atmosphere is transmitting in the wavelength range under consideration. Small amounts of methane, clouds, and haze do not greatly impede detectability. We found preliminary evidence that such a biosignature would be detectable on exoplanets within 15 pc, but further investigations are needed to corroborate this.

Exoplanet astronomy↗

Automating Anomaly Detection for Target systems at Spallation Neutron Source

The Spallation Neutron Source (SNS) at Oak Ridge National Laboratory, produces the world’s most intense pulse neutrons beams. An accelerated proton beam is directed into a mercury target to generate neutrons via spallation. The target system accounted for over 40% of the overall downtime of the facility in 2022. Thus, early detection in anomalies in the target systems can enable taking corrective actions to avoid failures and reduce downtime. Fault prognostics and anomaly detection in accelerators, both at SNS and outside, has largely focused on the beam side. This paper presents one the first studies exploring leveraging machine learning to automate the detection of anomalies in the target system. The target system consists of over 30 different interconnected subsystems, and the present work focuses on the mercury process system as a use case. Analyzing data from 28 process variables from 2022 and 2023, tree-based and reconstruction-based algorithms are employed to detect anomalies in archived data. The algorithms detected previously unreported anomalies, several of which were deemed alert worthy by human experts, particularly those found by reconstruction-based algorithms. Using data from each production run in the accelerator increased the generalizability of the models in time. Efforts are now underway to implement a workflow for incorporating human feedback to update the models and evaluating performance on unseen data. The models will eventually be integrated into the existing System Tracking and Reliability system with a web interface for automated anomaly detection and reporting along with a pathway for incorporating human feedback for model updates.

Raj, Anant [ORNL] (ORCID:0000000306711244)↗

Detection of Isotopes in Urban Source Search Low-Count Gamma Spectra Using Hopfield Neural Networks

Source search campaigns involve measurements of background gamma-ray spectra with a mobile detector-spectrometer traveling along arbitrarily chosen trajectories over a wide screening area. Radiation counts are typically measured with a tellurium-doped sodium iodide [NaI(Tl)] scintillator detector-spectrometer in short acquisition intervals, usually 1 s. The objective is to detect orphan isotopes with half-lives shorter than those of the isotopes in the natural background. In principle, radioisotopes can be identified by their unique gamma emission spectrum. However, detecting orphan isotopes in search data is challenging because low counts measured in short acquisition intervals result in incomplete spectral lines. In this study, we investigate the performance of a Hopfield neural network (HNN) that implements an auto-associative memory for the detection of isotopes of interest in an urban search campaign. The HNN is trained on one example of gamma spectra with well-resolved spectral lines of each isotope of interest. During testing, the auto-associative memory implementation of the HNN processes low-count gamma spectra with partially complete isotopic lines by matching incoming measurements to the closest one of its memory-stored patterns. The testing database consisted of almost 10 000 1-s gamma spectra, including measurements of orphan isotopes 137 Cs, 241 Am, and 131 I, obtained during two urban search surveys with a NaI(Tl) detector. The performance of the HNN detection algorithm was evaluated using precision, recall, and F1 scores, and benchmarked with a multiple linear regression (MLR) identification algorithm. In conclusion, the test results demonstrate that HNN outperforms MLR in the detection of all the isotopes of interest.

Auto associative memory↗

Capturing Complex Multivariate Time Series Interactions to Detect High-Risk Adverse Events During Flight

The reduction of aviation safety metrics below target thresholds continue to drive down the number of aviation fatalities and accidents. To meet future safety demands, sustained efforts by aviation agencies promoting safety assurance processes and systems have prompted ongoing research on identifying and mitigating in-flight risks. With the projected increase in passenger load factor and rollout of more autonomous systems into the national airspace, the need to detect high-risk events in-time or ahead-of-time is becoming increasingly crucial. New anomaly detection and precursor identification algorithms will need to scale to different airframes, levels of autonomy, and system complexity. While the pervasiveness of deep learning has resulted in the development of performant anomaly detection methods, these sophisticated models currently suffer from low end-user interpretability. Building off our previous work on identifying adverse events in multivariate flight data during descent, we propose a data-driven approach for detecting in-flight adverse events caused by the complex interplay of flight variables. Our approach utilizes ordinal patterns of important aircraft stability variables (e.g., airspeed and descent rate) to capture multivariate flight dynamics that can be used to predict the onset of unstable approaches, a high-risk adverse event that can occur during approach. Through the use of ordinal patterns, we aim to create more interpretable detection models of in-flight adverse events that can be translated to future autonomous systems without difficulty. Our analysis shows the presence of distinct ordinal pattern distributions that can be used to predict unstable approaches 1 minute ahead of time with an accuracy of 0.69 and a recall of 0.73 and 30 seconds ahead with an accuracy of 0.70 and a recall of 0.86.

Risk detection↗

Capturing Multivariate Time Series Interactions to Detect High‑Risk Instability During Approach

The reduction of aviation safety metrics below target thresholds continue to drive down the number of aviation fatalities and accidents. To meet future safety demands, sustained efforts by aviation agencies promoting safety assurance processes and systems have prompted ongoing research on identifying and mitigating in-flight risks. With the projected increase in passenger load factor and rollout of more autonomous systems into the national airspace, the need to detect high-risk events in-time or ahead-of-time is becoming increasingly crucial. New anomaly detection and precursor identification algorithms will need to scale to different airframes, levels of autonomy, and system complexity. While the pervasiveness of deep learning has resulted in the development of performant anomaly detection methods, these sophisticated models currently suffer from low end-user interpretability. Building off our previous work on identifying adverse events in multivariate flight data during descent, we propose a data-driven approach for detecting in-flight adverse events caused by the complex interplay of flight variables. Our approach utilizes ordinal patterns of important aircraft stability variables (e.g., airspeed and descent rate) to capture multivariate flight dynamics that can be used to predict the onset of unstable approaches, a high-risk adverse event that can occur during approach. Through the use of ordinal patterns, we aim to create more interpretable detection models of in-flight adverse events that can be translated to future autonomous systems without difficulty. Our analysis shows the presence of distinct ordinal pattern distributions that can be used to predict unstable approaches 1 minute ahead of time with an accuracy of 0.69 and a recall of 0.73 and 30 seconds ahead with an accuracy of 0.70 and a recall of 0.86.

Risk detection↗

Automated Label‐Free Assay for Viral Detection and Inhibitor Screening via Biomembrane‐Functionalized Microelectrode Arrays

Most virus infection assays have indirect readout such as virus number following entry (e.g., PCR, cell lysis). While effective, these technologies are labor‐intensive, require specialized environments (e.g., sterile or RNA‐free), and detect later‐stage viral events like lysis or cell death, lacking sensitivity to early fusion events. To address these limitations, we present biologically relevant 2D membrane materials, host‐cell‐derived supported lipid bilayers (hcd‐SLBs), integrated with organic microelectrode arrays (OMEAs) for detection of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) fusion. By overexpressing angiotensin‐converting enzyme 2 (ACE2) receptors on the native membranes, the platform functions as a viral sensor capable of detecting virus pseudo particles (VPPs) through the late pathway. Additionally, hcd‐SLBs extracted from human lung epithelium expressing native ACE2 detect fusion events through the early pathway. The platform's utility as a drug‐screening tool is demonstrated by testing antibodies targeting either the ACE2 on the host membrane or the viral spike (S) proteins. To enhance the throughput, microfluidics are integrated for automation and OMEAs are incorporated within each channel, miniaturizing the testing units. This system supports high‐throughput data generation, automation, and scalability, providing an efficient platform for viral fusion detection that advances the study of pathogen‐host interactions and accelerates antiviral drug discovery.

Biology↗

Automated Fire Detection for Industrial Settings with Pretrained Convolutional Networks

Early fire detection in industrial environments is critical to preventing equipment damage, personal injury, and operational disruptions. Traditional smoke detectors, while effective, often experience delays due to the time required for smoke to reach sensors, allowing fires to spread. Manual fire watch operations and human surveillance of camera feeds are resource-intensive and prone to human error. To address these challenges, this paper explores the application of convolutional neural networks for automated fire detection, specifically in industrial settings. By leveraging 11 different pre-trained machine vision models from TensorFlow and enhancing them with transfer learning on a custom-built industrial fire dataset, we optimized fire detection performance. Here, we analyzed each machine vision model architecture in terms of its depth, width, and input image resolution, considering both resource requirements and detection accuracy. We further explored the option of combining multiple models into an ensemble classifier to evaluate whether the performance improvements could justify the much greater computational complexity and other practical impacts. A cost-benefit analysis is presented to evaluate the trade-offs between performance and computational expense. Our findings identify that EfficientNetV2L, specifically tailored for industrial applications, provides the optimal balance between costs involved in training and using the model versus the overall fire detection performance. Additionally, we present a qualitative analysis of model performance using the technique of gradient-based class activation mapping to provide explainability by visualizing model decisions.

artificial intelligence↗

Anomaly Detection in Materials Digital Twins with Multiscale ICME for Additive Manufacturing

Detecting anomaly in fatigue and fracture experimental materials science is an interesting yet challenging topic. The reasons are threefold. First, the anomalous microstructure feature that gives rise to structural failure is small, sometimes in the order of 10 -7 of the interrogated volume. This, in turn, results in a highly imbalanced classification problem in machine learning (ML). Second, the consequence is high, in the sense that the test specimen is destructed in such case. Third, the convolution between microstructure stochasticity and the small probability of void nucleation, growth, and coalescence makes failure and fracture a hard-to-predict and challenging problem in materials science due to its irreproducibility, even experimentally. In this paper, we developed a materials digital twin and applied anomaly detection methods to detect voids and anomaly in additive manufacturing (AM). The materials digital twin is driven by two integrated computational materials engineering (ICME) models, which are kinetic Monte Carlo (kMC) and crystal plasticity finite element method (CPFEM). In conclusion, we demonstrated that by using anomaly detection, it is possible to detect voids and other defects in materials digital twin, which paves way for future research in integrating materials digital twin with its physical counterpart.

ICME↗

Autonomous anomaly detection of proliferation in the AGN-201 nuclear reactor digital twin

The expansion of global nuclear power necessitates advanced methods for analyzing proliferation indicators. This study introduces a novel application of the Isolation Forest Machine Learning (IFML) algorithm within a digital twin (DT) of the AGN-201 nuclear reactor to autonomously detect anomalies. Leveraging real-time operational data from the AGN-201 DT, the IFML algorithm identifies outliers without prior data labeling and operates as a lightweight, complementary approach to traditional physics-based anomaly detection methods for nuclear safeguards. In a simulated Red vs. Blue team exercise, the IFML algorithm successfully detected six significant unseen anomalies related to reactivity changes, achieving an accuracy of 99% for identifying operational deviationxs. These anomalies, caused by deliberate perturbations, were detected alongside known physics-based models, underscoring the potential of IFML to enhance real-time monitoring without displacing traditional methods. Further, this study highlights the applicability of IFML in nuclear environments by providing an additional, redundant layer of anomaly detection to improve safeguards and operational safety in complex systems.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Emerging anomaly detection techniques for electronic health records: A survey

Background Anomaly detection in electronic health records (EHRs) is a cornerstone of biomedical informatics, with direct implications for patient safety, clinical decision-making, and the prevention of healthcare fraud. Once guided primarily by simple rule-based methods, the field has advanced rapidly, driven by increased computing power, richer and more detailed health data, and the rise of machine learning and deep learning techniques. The objective of this paper is to provide a comprehensive overview of modern approaches to detecting anomalies in EHRs, outlining their strengths, limitations, and relevance to key healthcare challenges. We review traditional statistical methods alongside newer ML- and DL-based strategies and hybrid models, with particular attention to how these techniques support transparency and build clinical trust. Methods This paper presents a thorough and critical survey through systematic review (PRISMA-based) of the latest anomaly detection strategies in time-sequence data domains within electronic health record systems. Results We explore a broad spectrum of methodologies, including statistical models, supervised and unsupervised learning approaches, hybrid frameworks, and state-of-the-art ML-based techniques that collectively advance the precision and scalability of detecting anomalies in complex clinical datasets. In addition to mapping current capabilities, we address the enduring challenges that hinder widespread implementation and provide a forward-looking perspective on the future of anomaly detection in the data-rich landscape of modern healthcare. Summary The advancement in AI-based approaches is reported along with the basic principles of the individual approaches and their applicability. The increased availability of high-quality data, advancements in DL approaches, and enhanced computation power are leading to more frequent adaptation of DL-based approaches. Emerging DL-based approaches that have been adapted in other domains or recently applied in the EHR domain are also discussed in detail. Although DL-based approaches can improve model predictions by incorporating comorbidities, their application is limited in low-frequency data domains (e.g., when the total available data remains in the single digits). Therefore, the user must carefully consider the application based on data availability.

Anomaly detection↗