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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 307 records · Page 17

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NASA NTRS1997

Changes in the immune system during and after spaceflight

The results of immunological analyses before, during and after spaceflight, have established the fact that spaceflight can result in a blunting of the immune mechanisms of human crew members and animal test species. There is some evidence that the immune function changes in short-term flights resemble those occurring after acute stress, while the changes during long-term flights resemble those caused by chronic stress. In addition, this blunting of the immune function occurs concomitant with a relative increase in potentially infectious microorganisms in the space cabin environment. This combination of events results in an increased probability of inflight infectious events. The realization of this probability has been shown to be partially negated by the judicious use of a preflight health stabilization program and other operational countermeasures. The continuation of these countermeasures, as well as microbial and immunological monitoring, are recommended for continued spaceflight safety.

manned↗

NASA NTRS1987

Cell anomalies associated with spaceflight conditions

No abstract available

Review, Academic↗

NASA NTRS1993

Space flight and the immune system

Depression of lymphocyte response to mitogens in cosmonauts after space flight was reported for the first time in the early 1970s by Soviet immunologists. Today we know that depression of lymphocyte function affects at least 50% of space crew members. Investigations on the ground on subjects undergoing physical and psychological stress indicate that stress is a major factor in immune depression of astronauts. This is despite the fact that weightlessness per se has a strong inhibitory effect on lymphocyte activation in vitro. Although the changes observed never harmed the health of astronauts, immunological changes must be seriously investigated and understood in view of long-duration flight on space stations in an Earth orbit, to other planets such as Mars and to the Moon.

NASA Discipline Regulatory Physiology↗

NASA NTRS1962

Self erecting manned space laboratory

The Langley Research Center of the National Aeronautics and Space Administration is currently involved in several research programs on manned orbital space stations. This research effort is focused on seeking out and solving the problems which lie in the way of the eventual development of such a vehicle for use as a space laboratory. In conducting this research activity, it has been necessary to consider many vehicle configuration designs and operational concepts in some detail. The Langley Research Center space station study program has been in progress for several years, and it was consisted of both in-house activities and contracted efforts with industry. In the early Langley Research Center studies, only zero-gravity configurations were considered; however, the requirement for artificial gravity simulation for experimental purposes was soon added. Human factors considerations indicated that large diameter vehicles with slow rotational velocities generally permit the most comfortable living conditions for the crew. The configurations which were studied were required to be compatible with the planned launch vehicles such as Saturn, and manned spacecraft such as Mercury.

Manned Orbital Space Station (MOSS)↗

NASA NTRS1962

THE IMPACT OF THE LUNAR ORBIT RENDEZVOUS CONCEPT OF THE TEST, OPERATIONS AND SUPPORT PROBLEMS OF LUNAR EXPLORATION

Effect of lunar orbit rendezvous concept on tests, operations and support problems of lunar exploration

LUNAR EXPLORATION↗

NASA NTRS1963

FORCASTING TEN YEARS OF PROGRESS IN SPACE EXPLORATION

Explore the source record for details and available documents.

SPACE EXPLORATION↗

NASA NTRS1963

SIMULATION AND TRAINING FACILITIES

As we move toward future manned spaceflight programs, there will be brought into playa broad range of training and simulation facilities in NASA, other government agencies, and private industry. We use the term "facility" in the broadest sense-from an airplane pressed into use for zero-gravity familiarization to a large moving-base simulator housed in its own permanent building.

SIMULATION↗

NASA NTRS1962