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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 307 records · Page 17
All sourcesNASA NTRSDOE OSTI
NASA NTRS2000

Viral carcinogenesis: revelation of molecular mechanisms and etiology of human disease

The RNA and DNA tumor viruses have made fundamental contributions to two major areas of cancer research. Viruses were vital, first, to the discovery and analysis of cellular growth control pathways and the synthesis of current concepts of cancer biology and, second, to the recognition of the etiology of some human cancers. Transforming retroviruses carry oncogenes derived from cellular genes that are involved in mitogenic signalling and growth control. DNA tumor viruses encode oncogenes of viral origin that are essential for viral replication and cell transformation; viral oncoproteins complex with cellular proteins to stimulate cell cycle progression and led to the discovery of tumor suppressors. Viral systems support the concept that cancer development occurs by the accumulation of multiple cooperating events. Viruses are now accepted as bona fide etiologic factors of human cancer; these include hepatitis B virus, Epstein-Barr virus, human papillomaviruses, human T-cell leukemia virus type I and hepatitis C virus, plus several candidate human cancer viruses. It is estimated that 15% of all human tumors worldwide are caused by viruses. The infectious nature of viruses distinguishes them from all other cancer-causing factors; tumor viruses establish long-term persistent infections in humans, with cancer an accidental side effect of viral replication strategies. Viruses are usually not complete carcinogens, and the known human cancer viruses display different roles in transformation. Many years may pass between initial infection and tumor appearance and most infected individuals do not develop cancer, although immunocompromised individuals are at elevated risk of viral-associated cancers. Variable factors that influence viral carcinogenesis are reviewed, including possible synergy between viruses and environmental cofactors. The difficulties in establishing an etiologic role for a virus in human cancer are discussed, as well as the different approaches that proved viral links to cancer. Future directions for tumor virus studies are considered.

NASA Program Biomedical Research and Countermeasur↗
NASA NTRS2011

Intraseasonal Variability in the Atmosphere-Ocean Climate System. Second Edition

Understanding and predicting the intraseasonal variability (ISV) of the ocean and atmosphere is crucial to improving long-range environmental forecasts and the reliability of climate change projections through climate models. This updated, comprehensive and authoritative second edition has a balance of observation, theory and modeling and provides a single source of reference for all those interested in this important multi-faceted natural phenomenon and its relation to major short-term climatic variations.

Lau, William K. M.↗
NASA NTRS2019

Testing and Improving a UAV-Based System Designed for Wetland Methane Source Measurements

Wetlands are the single highest emitting methane source category, but the magnitude of wetland fluxes remains difficult to fully characterize due to their large spatial extent and heterogeneity. Fluxes can vary with land surface conditions, vegetation type, and seasonal changes in environmental conditions. Unmanned aerial vehicles (UAVs) are an emerging platform to better characterize spatial variability in these natural ecosystems. While presenting some advantages over traditional techniques like towers and flux chambers, in that they are mobile vertically and horizontally, their use is still challenging, requiring continued improvement in sensor technology and field measurement approaches. In this work, we employ a small, fast response laser spectrometer on a Matrice 600 hexacopter. The system was previously deployed successfully for 40 flights conducted in a four-day period in 2018 near Fairbanks, Alaska. These flights revealed several potential areas for improvement, including: vertical positioning accuracy, the need for sensor health indicators, and approaches to deal with low wind speeds. An additional set of flights was conducted this year near Antioch in California. Flights were conducted several meters above ground up to 15-25 m in a curtain pattern. These curtains were flown both upwind and downwind of a tower site, allowing us to calculate a mass balance methane flux estimate that can be compared to eddy covariance fluxes from the tower. Testing will better characterize the extent to which altitude drifts in-flight and how GPS values compare with measurements from the onboard LIDAR, as well as the agreement between two-dimensional wind speed and direction on the ground versus measured onboard the UAV. Hardware improvements to the sensor and GPS are being considered to help reduce these sources of uncertainty. Results of this testing and how system performance relates to needs for quantifying wetland fluxes, will be presented.

Golston, Levi↗
NASA NTRS2024

Quantifying Caloric Expenditure During Zero-G Exercise

BACKGROUND: Exercise is a fundamental component of maintaining astronaut health on long-duration space missions, where the microgravity environment poses unique challenges to physiological homeostasis. Accurate quantification of energy expenditure during such exercises is crucial for optimizing nutritional and physical health strategies for spacefarers. OBJECTIVE: This study aims to develop a comprehensive model to estimate caloric expenditure during exercise in a microgravity environment, employing a combination of spirometry, heart rate data, and other relevant parameters. By assessing energy utilization under these conditions, we seek to facilitate enhanced health management protocols for astronauts in space. METHODS & OUTCOMES: A multivariate predictive model will be constructed, utilizing spirometry and heart rate data, coupled with additional physiological and environmental parameters. A systematic approach will be applied to analyze the relationship between these variables and energy expenditure during various exercises. The proposed model will subsequently undergo rigorous validation to ensure accuracy and reliability. This research is expected to yield a precise and reliable predictive model, contributing to improved strategies for exercise prescription and nutritional intake, addressing the unique challenges presented by microgravity environments. We anticipate that our findings will support the development of more effective health maintenance protocols for astronauts during extended space missions, mitigating the adverse effects of space travel on the human body. SIGNIFICANCE: The development of an accurate and adaptable model to quantify caloric expenditure during exercise in space represents a pivotal advancement in space medicine. The insights gained from this study have the potential to inform the design of enhanced health and wellness strategies, ensuring the well-being and operational effectiveness of astronauts in long-duration space missions.

Calorie↗
NASA NTRS1987

Environmental effects on laser-induced fluorescence spectra of natural waters

Laser fluorosensing can be used to monitor dissolved organic carbon (DOC), but analysis of the data can be hindered by several environmental phenomena. These phenomena include attenuation of the laser beam and differential attenuation of the fluorescence by the water column, variability in the molecular weight composition of the DOC, and temperature, pH, and metal ion effects on DOC fluorescence. These factors are discussed in terms of their effect on laboratory and remote field data analysis. Experimental results are provided. Analysis of fluorosensor data of DOC may be improved by compensating for the environmental factors. An improved methodology is discussed, and a suggestion is made for indirect monitoring of pH and metal ion concentration.

Vodacek, Anthony↗
NASA NTRS1992

Environmental monitoring and research at the John F. Kennedy Space Center

The Biomedical Operations and Research Office at the NASA John F. Kennedy Space Center has been supporting environmental monitoring and research since the mid-1970s. Program elements include monitoring of baseline conditions to document natural variability in the ecosystem, assessments of operations and construction of new facilities, and ecological research focusing on wildlife habitat associations. Information management is centered around development of a computerized geographic information system that incorporates remote sensing and digital image processing technologies along with traditional relational data base management capabilities. The proactive program is one in which the initiative is to anticipate potential environmental concerns before they occur and, by utilizing in-house expertise, develop impact minimization or mitigation strategies to reduce environmental risk.

Hall, C. R.↗
NASA NTRS1992

Space sickness predictors suggest fluid shift involvement and possible countermeasures

Preflight data from 64 first time Shuttle crew members were examined retrospectively to predict space sickness severity (NONE, MILD, MODERATE, or SEVERE) by discriminant analysis. From 9 input variables relating to fluid, electrolyte, and cardiovascular status, 8 variables were chosen by discriminant analysis that correctly predicted space sickness severity with 59 pct. success by one method of cross validation on the original sample and 67 pct. by another method. The 8 variables in order of their importance for predicting space sickness severity are sitting systolic blood pressure, serum uric acid, calculated blood volume, serum phosphate, urine osmolality, environmental temperature at the launch site, red cell count, and serum chloride. These results suggest the presence of predisposing physiologic factors to space sickness that implicate a fluid shift etiology. Addition of a 10th input variable, hours spent in the Weightless Environment Training Facility (WETF), improved the prediction of space sickness severity to 66 pct. success by the first method of cross validation on the original sample and to 71 pct. by the second method. The data suggest that WETF training may reduce space sickness severity.

Simanonok, K. E.↗
NASA NTRS1976

Heat pipes for spacecraft temperature control: An assessment of the state-of-the-art

Spacecraft applications that require the efficient cooling of high-powered components, the precise temperature control of sensitive electronic and optical components, and the protection of cooled components from temporary, adverse environmental conditions are increasing. Heat pipes using gas, vapor, liquid, or voltage control to provide variable conductance or diode thermal behavior have been and are continuing to be developed to meet increasingly difficult requirements. The various control techniques are critically evaluated using characteristic features and properties, including heat transport capability, volume and mass requirements, complexity and ease of fabrication, reliability, and control characteristics. As a result, advantages and disadvantages of specific approaches are derived and discussed. Using four development levels, the state-of-the-art of the various heat pipe temperature control techniques is assessed.

Groll, M.↗
NASA NTRS1977

The development of a model for predicting passenger acceptance of short-haul air transportation systems

Meaningful criteria and methodology for assessing, particularly in the area of ride quality, the potential acceptability to the traveling public of present and future transportation systems were investigated. Ride quality was found to be one of the important variables affecting the decision of users of air transportation, and to be influenced by several environmental factors, especially motion, noise, pressure, temperature, and seating. Models were developed to quantify the relationship of subjective comfort to all of these parameters and then were exercised for a variety of situations. Passenger satisfaction was found to be strongly related to ride quality and was so modeled. A computer program was developed to assess the comfort and satisfaction levels of passengers on aircraft subjected to arbitrary flight profiles over arbitrary terrain. A model was deduced of the manner in which passengers integrate isolated segments of a flight to obtain an overall trip comfort rating. A method was established for assessing the influence of other links (e.g., access, terminal conditions) in the overall passenger trip.

Kuhlthau, A. R.↗
NASA NTRS1994

Empirical Modeling of Plant Gas Fluxes in Controlled Environments

As humans extend their reach beyond the earth, bioregenerative life support systems must replace the resupply and physical/chemical systems now used. The Controlled Ecological Life Support System (CELSS) will utilize plants to recycle the carbon dioxide (CO2) and excrement produced by humans and return oxygen (O2), purified water and food. CELSS design requires knowledge of gas flux levels for net photosynthesis (PS(sub n)), dark respiration (R(sub d)) and evapotranspiration (ET). Full season gas flux data regarding these processes for wheat (Triticum aestivum), soybean (Glycine max) and rice (Oryza sativa) from published sources were used to develop empirical models. Univariate models relating crop age (days after planting) and gas flux were fit by simple regression. Models are either high order (5th to 8th) or more complex polynomials whose curves describe crop development characteristics. The models provide good estimates of gas flux maxima, but are of limited utility. To broaden the applicability, data were transformed to dimensionless or correlation formats and, again, fit by regression. Polynomials, similar to those in the initial effort, were selected as the most appropriate models. These models indicate that, within a cultivar, gas flux patterns appear remarkably similar prior to maximum flux, but exhibit considerable variation beyond this point. This suggests that more broadly applicable models of plant gas flux are feasible, but univariate models defining gas flux as a function of crop age are too simplistic. Multivariate models using CO2 and crop age were fit for PS(sub n), and R(sub d) by multiple regression. In each case, the selected model is a subset of a full third order model with all possible interactions. These models are improvements over the univariate models because they incorporate more than the single factor, crop age, as the primary variable governing gas flux. They are still limited, however, by their reliance on the other environmental conditions under which the original data were collected. Three-dimensional plots representing the response surface of each model are included. Suitability of using empirical models to generate engineering design estimates is discussed. Recommendations for the use of more complex multivariate models to increase versatility are included.

Cornett, Jessie David↗
NASA NTRS2010

NASA'S Water Resources Element Within the Applied Sciences Program

The NASA Applied Sciences Program works within NASA Earth sciences to leverage investment of satellite and information systems to increase the benefits to society through the widest practical use of NASA research results. Such observations provide a huge volume of valuable data in both near-real-time and extended back nearly 50 years about the Earth's land surface conditions such as land cover type, vegetation type and health, precipitation, snow, soil moisture, and water levels and radiation. Observations of this type combined with models and analysis enable satellite-based assessment of numerous water resources management activities. The primary goal of the Earth Science Applied Science Program is to improve future and current operational systems by infusing them with scientific knowledge of the Earth system gained through space-based observation, model results, and development and deployment of enabling technologies, systems, and capabilities. Water resources is one of eight elements in the Applied Sciences Program and it addresses concerns and decision making related to water quantity and water quality. With increasing population pressure and water usage coupled with climate variability and change, water issues are being reported by numerous groups as the most critical environmental problems facing us in the 21st century. Competitive uses and the prevalence of river basins and aquifers that extend across boundaries engender political tensions between communities, stakeholders and countries. Mitigating these conflicts and meeting water demands requires using existing resources more efficiently. The potential crises and conflicts arise when water is competed among multiple uses. For example, urban areas, environmental and recreational uses, agriculture, and energy production compete for scarce resources, not only in the Western U.S. but throughout much of the U.S. but also in many parts of the world. In addition to water availability issues, water quality related problems are seriously affecting human health and our environment. The NASA Water Resources Program Element works to use NASA products to address these critical issues.

Toll, David↗
NASA NTRS2011

NASA Water Resources Program

With increasing population pressure and water usage coupled with climate variability and change, water issues are being reported by numerous groups as the most critical environmental problems facing us in the 21st century. Competitive uses and the prevalence of river basins and aquifers that extend across boundaries engender political tensions between communities, stakeholders and countries. In addition to the numerous water availability issues, water quality related problems are seriously affecting human health and our environment. The potential crises and conflicts especially arise when water is competed among multiple uses. For example, urban areas, environmental and recreational uses, agriculture, and energy production compete for scarce resources, not only in the Western U.S. but throughout much of the U.S. and also in numerous parts of the world. Mitigating these conflicts and meeting water demands and needs requires using existing water resources more efficiently. The NASA Water Resources Program Element works to use NASA products and technology to address these critical water issues. The primary goal of the Water Resources is to facilitate application of NASA Earth science products as a routine use in integrated water resources management for the sustainable use of water. This also includes the extreme events of drought and floods and the adaptation to the impacts from climate change. NASA satellite and Earth system observations of water and related data provide a huge volume of valuable data in both near-real-time and extended back nearly 50 years about the Earth's land surface conditions such as precipitation, snow, soil moisture, water levels, land cover type, vegetation type, and health. NASA Water Resources Program works closely to use NASA and Earth science data with other U.S. government agencies, universities, and non-profit and private sector organizations both domestically and internationally. The NASA Water Resources Program organizes its projects under five functional themes. I) Streamflow and Flood Forecasting 2) Water Supply and Irrigation (includes evapotranspiration) 3) Drought 4) Water Quality 5) Climate and Water Resources. To maximize this activity NASA Water Resources Program works closely with other government agencies (e.g., the National Oceanic and Atmospheric Administration (NOAA); the U.S. Department of Agriculture (USDA); the U.S. Geological Survey (USGS); the Environmental Protection Agency (EPA), USAID, the Air Force Weather Agency (AFWA)), universities, non-profit national and international organizations, and the private sector. The NASA Water Resources program currently is funding 21 active projects under the functional themes (http://wmp.gsfc.nasa.gov & http://science.nasa.gov/earth-science/applied-sciences/).

Toll, David L.↗
NASA NTRS2012

NASA's Water Solutions Using Remote Sensing

NASA Water Resources works within Earth sciences to leverage investments of space-based observation, model results, and development and deployment of enabling technologies, systems, and capabilities into water resources management decision support tools for the sustainable use of water. Earth science satellite observations and modelling products provide a huge volume of valuable data in both near-real-time and extended back nearly 50 years about the Earth's land surface conditions such as land cover type, vegetation type and health, precipitation, snow, soil moisture, and water levels and radiation. Observations of this type combined with models and analysis enable satellite-based assessment of the water cycle. With increasing population pressure and water usage coupled with climate variability and change, water issues are being reported by numerous groups as the most critical environmental problems facing us in the 21st century. Competitive uses and the prevalence of river basins and aquifers that extend across boundaries engender political tensions between communities, stakeholders and countries. The NASA Water Resources Program has the objective to provide NASA products to help deal with these issues with the goal for the sustainable use of water. The Water Resources program organizes its projects under five functional themes: 1) stream-flow and flood forecasting; 2) water consumptive use (includes evapotranspiration) and irrigation; 3) drought; 4) water quality; and 5) climate and water resources. NASA primarily works with national and international groups such as other US government agencies (NOAA, EPA, USGS, USAID) and various other groups to maximize the widest use of the water products. A summary of NASA's water activities linked to helping solve issues for developing countries will be highlighted.

Toll, David↗
NASA NTRS2000

Interannual Variability in the Meridional Transport of Water Vapor

The zonal-mean meridional transport of water vapor across the globe is evaluated using the National Centers for Environmental Prediction-National Center for Atmospheric Research (NCEP-NCAR) reanalysis for 1948-97. The shape of the meridional profile of the climatological mean transport closely resembles that of previous mean climate descriptions, but values tend to be notably larger than in climatologies derived from radiosonde-only-based analyses. The unprecedented length of the NCEP-NCAR dataset invites a focus on interannual variations in the zonal-mean moisture transport, and these results for northern winter are highlighted here. Although interannual variability in the transport is typically small at most latitudes, a significant ENSO signal is present, marked by a strengthening of water vapor transports over much of the winter hemisphere during warm events. Because of an increase in tropical sea surface temperatures and in the frequency of warm events relative to cold events in the latter half of the 50-yr record, this interannual signal projects onto an overall trend toward enhanced meridional moisture transports in the global hydrological cycle.

Cohen, Judah L.↗
NASA NTRS1975

Engine design considerations for 2nd generation supersonic transports

The environmental and economic goals projected for advanced supersonic transports will require revolutionary improvements in propulsion systems. Variable cycle engine concepts that incorporate unique components and advanced technologies show promise in meeting these goals. Pratt & Whitney Aircraft is conducting conceptual design studies of variable cycle engine concepts under NASA sponsorship. This paper reviews some of the design considerations for these engine concepts. Emphasis is placed on jet noise abatement, reduction of emissions, performance improvements, installation considerations, hot-section characteristics and control system requirements. Two representative variable cycle engine concepts that incorporate these basic design considerations are described.

Howlett, R. A.↗
NASA NTRS1981

Advanced supersonic transport propulsion and configuration technology improvements

This paper presents the results of recent Douglas Aircraft Company integration studies for an advanced supersonic transport. The studies include technology improvements such as superplastic formed and diffusion-bonded titanium sandwich primary structure, composite secondary structure, bicone engine inlet, improved mechanical suppressors based on flight test data, improved aerodynamic efficiency based on wind tunnel test data, and updated performance for both variable-cycle and low-bypass-ratio engines. Technology development requirements for an economically viable and environmentally acceptable advanced supersonic transport are defined through these studies. A new Douglas Aircraft Company baseline supersonic transport designed to carry 350 passengers is defined for cost comparisons.

Rowe, W. T.↗
NASA NTRS1993

A regional rainfall climatology over Mexico and the southwest United States derived from passive microwave and geosynchronous infrared data

A three-year climatology of satellite-estimated rainfall for the warm season for the southwest United States and Mexico has been derived from data from the Special Sensor Microwave Imager (SSM/I). The microwave data have been stratified by month (June, July, August), year (1988, 1989, 1990), and time of day (morning and evening orbits). A rain algorithm was employed that relates 86-GHz brightness temperatures to rain rate using a coupled cloud-radiative transfer model. Results identify an early evening maximum in rainfall along the western slope of the Sierra Madre Occidental during all three months. A prominent morning rainfall maximum was found off the western Mexican coast near Mazatlan in July and August. Substantial differences between morning and evening estimates were noted. To the extent that three years constitute a climatology, results of interannual variability are presented. Results are compared and contrasted to high-resolution (8 km, hourly) infrared cloud climatologies, which consist of the frequency of occurrence of cloud colder than -38 C and -58 C. This comparison has broad implications for the estimation of rainfall by simple (cloud threshold) techniques. By sampling the infrared data to approximate the time and space resolution of the microwave, we produce ratios (or adjustment factors) by which we can adjust the infrared rain estimation schemes. This produces a combined microwave/infrared rain algorithm for monthly rainfall. Using a limited set of raingage data as ground truth, an improvement (lower bias and root-mean-square error) was demonstrated by this combined technique when compared to either method alone. The diurnal variability of convection during July 1990 was examined using hourly rain estimates from the Geostationary Operational Environmental Satellite (GOES) precipitation index and the convective stratiform technique, revealing a maximum in estimated rainfall from 1800 to 2100 local time. It is in this time period when the SSM/I evening orbit occurs. A high-resolution topographic database was available to aid in interpreting the influence of topography on the rainfall patterns.

Negri, Andrew J.↗