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At least 307 records · Page 17

Watching Without Seeing a Tool to Surveil Astronaut Health Outcomes While Maintaining Astronaut Medical Privacy

BACKGROUND The Privacy Act of 1974 regulates the use a nd disclosure of personally identifiable information by US Federal agencies. The Act applies to biographical, financial, a nd other identity-linked information, a s well a s personal health information (PHI). As such, the use of astronaut PHI is limited to authorized personnel for preapproved uses, with data reporting often limited to aggregated information about groups. These limitations on the use a nd reporting of astronaut PHI complicates surveillance efforts, wherein epidemiologists a t the National Aeronautics and Space Administration (NASA)monitor the incidence of targeted health conditions in the astronaut population, or to discover emerging trends of aging and disease. Stratification on one or more covariates –particularly time-period, sex, a nd mission participation –can lead to extremely small datasets such that the reporting of results is potentially attributable to individuals. An additional challenge is the small size of the astronaut population, both in terms of numbers of individuals a s well a s in terms of density of exposure time. Such small datasets yield volatile rate estimates that are difficult to interpret. To a id the epidemiological surveillance efforts, a surveillance tool is required that can (a) satisfy the need for rapid computation of condition-specific incidence and mortality rates; (b) improve the statistical estimates of these estimated rates; and (c) maintain astronaut privacy. Here we describe a nd demonstrate such a tool. METHODS We devised a system that models incidence a nd mortality rates rather than calculating them directly. This ha s the advantage of using all the available data to derive the estimates, lea ding to rates that a re not attributable to any one individual, a nd a re a s numerically stable a s they can be given the extremely limited data. The system models disease endpoints using a Poisson regression model with exposure density (measured in person-years) a s a n offset term. By doing so the model is estimating event counts per person-year, equivalent to modeling the rates directly. It uses a standard (pre-specified)set of covariates; the system does not engage in “model-building” as model parsimony is not the goa l. Instead, it is explicitly recognized that if a covariate is not statistically significant a nd not a confounder then it will likely have very little effect on the estimate of the incidence a nd mortality rates. Users are able to specify the disease endpoint of interest and the covariates over which they would like to stratify. The system then uses the resulting model to compute the estimated rates for the user-chosen configuration of variables as visualizes those either over an age range within a specified time-period, or over time for astronauts with a specified age range. RESULTS The first iteration of the tool computes incidence a nd mortality rates for cardiovascular conditions and cancers. Code ha s been developed to retrieve the appropriate data from the IMPALA analysis platform, compute the models for incidence a nd mortality, a nd then use those models to generate the corresponding rate curves. A companion graphical user interface allows the user to specify the curves and visualize the results. CONCLUSIONS It is important to note that the rapid surveillance tool described here is neither meant to be a definitive assessment of the incidence or mortality of any particular disease or condition in the astronaut population, nor is it meant to be used for research purposes. Rather, it is meant as an early indicator that in-depth investigation may be warranted. By automating a repetitive process and leveraging carefully curated astronaut health outcomes, the tool makes possible a rapid “first look” into known areas of concern, and, if used judiciously, may surface new areas of concern for long-term astronaut health. This work is supported in part by the Translational Research Institute for Space Health (TRISH) through NASA Cooperative Agreement NNX16AO69A.

R J Reynolds↗

The effects of terrestrial weathering on samarium-neodymium isotopic composition of ordinary chondrites

Following their fall to Earth, meteorites experience weathering. In this systematic study, we evaluate the trace element composition of ordinary chondrites from the Antarctic cold desert, and Atacama (Chile) and Lut (Iran) hot deserts, with an emphasis on rare earth elements (REE). Our data confirms that terrestrial weathering of meteorites in hot deserts changes their trace element (Sr, Ba, REE, Hf, Th, and U) concentrations. However, weathering effects in majority of Antarctic samples are limited to slight Ba, REE, Hf, and Th depletions and in some case to U enrichment. In comparison to the Antarctic meteorites, hot desert samples show greater disturbances and REE fractionation relative to the average fall values. We measured the Sm-Nd isotopic composition of the hot desert meteorites that have heavily affected REE compositions. Our Sm-Nd isotopic data show a significant effect of terrestrial weathering evidenced by non-CHUR (147)Sm/(144)Nd and (143)Nd/(144)Nd ratios. Measurements show a higher variation and lower values of (147)Sm/(144)Nd for the Atacama samples than those from the Lut Desert. Deviations from CHUR (147)Sm/(144)Nd value are in positive accordance with the degree of La/Lu fractionation caused by weathering. The ɛNd values of Atacama and Lut deserts meteorites range from −2.20 to +1.61, which is wider than the −1.07 to +0.64 range for falls. We suggest that disturbance of primary Sm/Nd ratios resulting from mixing with terrestrial components originating from soil during weathering is responsible for lower (147)Sm/(144)Nd ratio in these meteorites. The majority of the Atacama meteorites regardless of their weathering degrees have their REE compositions and ɛNd affected by terrestrial contamination. Both (147)Sm/(144)Nd ratio and ɛNd values show no straightforward relationship with weathering degree. However, in both cases the samples with the highest negative isotopic disturbances are H chondrites from the Atacama and Lut deserts. In addition, Ba concentration shows a negative correlation with (147)Sm/(144)Nd ratio. Care must be taken into account while dealing with samples collected from hot deserts, even fresh-looking ones.

Isotope geochemistry↗

Duration of a Magma Ocean and Subsequent Mantle Overturn in Mars: Evidence from Nakhlites

It is now generally accepted that the heat produced by accretion, short-lived radioactive elements such as Al-26, and gravitational energy from core formation was sufficient to at least partially melt the silicate portions of terrestrial planets resulting in a global-scale magma ocean. More particularly, in Mars, the geochemical signatures displayed by shergottites, are likely inherited from the crystallization of this magma ocean. Using the short-lived chronometer Sm-146 - Nd-142 (t(sup 1/2) = 103 Myr), the duration of the Martian magma ocean (MMO) has been evaluated to being less than 40 Myr, while recent and more precise ND-142/ND-144 data were used to evaluate the longevity of the MMO to approximately 100 Myr after the solar system formation. In addition, it has been proposed that the end of the crystallization of the MMO may have triggered a mantle overturn, as a result of a density gradient in the cumulate layers crystallized at different levels. Dating the mantle overturn could hence provide additional constraint on the duration of the MMO. Among SNC meteorites, nakhlites are characterized by high epsilon W-182 of approximately +3 and an epsilon Nd-142 similar to depleted shergottites of +0.6-0.9. It has hence been proposed that the source of nakhlites was established very early in Mars history (approximately 8-10 Myr). However, the times recorded in HF-182-W-182 isotope system, i.e. when 182Hf became effectively extinct (approximately 50 Myr after solar system formation) are less than closure times recorded in the Sm-146-Nd-142 isotope system (with a full coverage of approximately 500 Myr after solar system formation). This could result in decoupling between the present-day measured epsilon W-182 and epsilon Nd-142 as the SM-146 may have recorded later differentiation events in epsilon ND-142 not observed in epsilon W-182 values. With these potential complexities in short-lived chronological data for SNC's in mind, new Hf-176/Hf-177, Nd-143/Nd-144 and Nd-142/Nd-144 were obtained for three nakhlites (Nakhla, MIL03346 and Yamato000593). These new data are combined with previous epsilon W-182 data, to investigate potential discrepancies between the Hf-182-W-182 and Sm-146-Nd-142 systematics, and the relationship between the source of nakhlites and a crystallizing magma ocean

Debaille, V.↗

Untangling causality in midlatitude aerosol–cloud adjustments

Aerosol–cloud interactions represent the leading uncertainty in our ability to infer climate sensitivity from the observational record. The forcing from changes in cloud albedo driven by increases in cloud droplet number (Nd) (the first indirect effect) is confidently negative and has narrowed its probable range in the last decade, but the sign and strength of forcing associated with changes in cloud macrophysics in response to aerosol (aerosol–cloud adjustments) remain uncertain. This uncertainty reflects our inability to accurately quantify variability not associated with a causal link flowing from the cloud microphysical state to the cloud macrophysical state. Once variability associated with meteorology has been removed, covariance between the liquid water path (LWP) averaged across cloudy and clear regions (here characterizing the macrophysical state) and Nd (characterizing the microphysical) is the sum of two causal pathways linking Nd to LWP: Nd altering LWP (adjustments) and precipitation scavenging aerosol and thus depleting Nd. Only the former term is relevant to constraining adjustments, but disentangling these terms in observations is challenging. We hypothesize that the diversity of constraints on aerosol–cloud adjustments in the literature may be partly due to not explicitly characterizing covariance flowing from cloud to aerosol and aerosol to cloud. Here, we restrict our analysis to the regime of extratropical clouds outside of low-pressure centers associated with cyclonic activity. Observations from MAC-LWP (Multisensor Advanced Climatology of Liquid Water Path) and MODIS are compared to simulations in the Met Office Unified Model (UM) GA7.1 (the atmosphere model of HadGEM3-GC3.1 and UKESM1). The meteorological predictors of LWP are found to be similar between the model and observations. There is also agreement with previous literature on cloud-controlling factors finding that increasing stability, moisture, and sensible heat flux enhance LWP, while increasing subsidence and sea surface temperature decrease it. A simulation where cloud microphysics are insensitive to changes in Nd is used to characterize covariance between Nd and LWP that is induced by factors other than aerosol–cloud adjustments. By removing variability associated with meteorology and scavenging, we infer the sensitivity of LWP to changes in Nd. Application of this technique to UM GA7.1 simulations reproduces the true model adjustment strength. Observational constraints developed using simulated covariability not induced by adjustments and observed covariability between Nd and LWP predict a 25 %–30 % overestimate by the UM GA7.1 in LWP change and a 30 %–35 % overestimate in associated radiative forcing.

Daniel T. McCoy↗

Thermal effects on cavity stability of chromium- and neodymium-doped gadolinium scandium gallium garnet laser under solar-simulator pumping

Results are presented on testing a Cr- and Nd-codoped Gd-Sc-Ga-garnet (Cr:Nd:GSGG) crystal and a Nd:YAG crystal (both of 3.2 mm diam and 76-mm long) for pulsed and CW laser operations using a flashlamp and solar simulator as pumping sources. Results from experiments with the flashlamp show that, at pulse lengths of 0.11, 0.28, and 0.90 ms, the slope efficiency of the Cd:Nd:GSGG crystal was higher than that of the Nd:YAG crystal and increased with pulse width. With the solar simulator, however, the CW laser operation of the Cr:Nd:GSGG crystal was limited to intensities not greater than 1500 solar constants, while the Nd:YAG laser successfully performed for all pump beam intensities available. It was found that the exposure for several minutes of the Cr:Nd:GSGG crystal to pump beam intensity of 3000 solar constants led to its damage by thermal cracking, indicating that a better solar-pumped CW laser performance may be difficult to realize with rod geometry.

Kim, Kyong H.↗

Polarimetric Retrievals of Cloud Droplet Number Concentrations

Cloud droplet number concentration (Nd) is an important parameter of liquid clouds and is crucial to understanding aerosol-cloud interactions. It couples boundary layer aerosol composition, size and concentration with cloud reflectivity. It affects cloud evolution, precipitation, radiative forcing, global climate and, through observation, can be used to partially monitor the first indirect effect. With its unique combination of multi-wavelength, multi-angle, total and polarized reflectance measurements, the Research Scanning Polarimeter (RSP) retrieves Nd with relatively few assumptions. The approach involves measuring cloud optical thickness, mean droplet extinction cross-section and cloud physical thickness. Polarimetric observations are capable of measuring the effective variance, or width, of the droplet size distribution. Estimating cloud geometrical thickness is also an important component of the polarimetric Nd retrieval, which is accomplished using polarimetric measurements in a water vapor absorption band to retrieve the amount of in-cloud water vapor and relating this to physical thickness. We highlight the unique abilities and quantify uncertainties of the polarimetric approach. We validate the approach using observational data from the North Atlantic and Marine Ecosystems Study (NAAMES). NAAMES targets specific phases in the seasonal phytoplankton lifecycle and ocean-atmosphere linkages. This study provides an excellent opportunity for the RSP to evaluate its approach of sensing Nd over a range of concentrations and cloud types with in situ measurements from a Cloud Droplet Probe (CDP). The RSP and CDP, along with an array of other instruments, are flown on the NASA C-130 aircraft, which flies in situ and remote sensing legs in sequence. Cloud base heights retrieved by the RSP compare well with those derived in situ (R=0.83) and by a ceilometer aboard the R.V. Atlantis (R=0.79). Comparing geometric mean values from 12 science flights throughout the NAAMES-1 and NAAMES-2 campaigns, we find a strong correlation between Nd retrieved by the RSP and CDP (R=0.96). A linear least squares fit has a slope of 0.92 and an intercept of 0.3 cm−3. Uncertainty in this comparison can be attributed to cloud 3D effects, nonlinear liquid water profiles, multilayered clouds, measurement uncertainty, variation in spatial and temporal sampling, and assumptions used within the method. Radiometric uncertainties of the RSP measurements lead to biases on derived optical thickness and cloud physical thickness, but these biases largely cancel out when deriving Nd for most conditions and geometries. We find that a polarimetric approach to sensing Nd is viable and the RSP is capable of accurately retrieving Nd for a variety of cloud types and meteorological conditions.

Droplet concentration↗

The Impact of Sampling Strategy on the Cloud Droplet Number Concentration Estimated From Satellite Data

Cloud droplet number concentration (Nd) is of central importance to observation-based estimates of aerosol indirect effects, being used to quantify both the cloud sensitivity to aerosol and the base state of the cloud. However, the derivation of Nd from satellite data depends on a number of assumptions about the cloud and the accuracy of the retrievals of the cloud properties from which it is derived, making it prone to systematic biases. A number of sampling strategies have been proposed to address these biases by selecting the most accurate Nd retrievals in the satellite data. This work compares the impact of these strategies on the accuracy of the satellite retrieved Nd, using a selection of in situ measurements. In stratocumulus regions, the MODIS Nd retrieval is able to achieve a high precision (r2 of 0.5–0.8). This is lower in other cloud regimes but can be increased by appropriate sampling choices. Although the Nd sampling can have significant effects on the Nd climatology, it produces only a 20 % variation in the implied radiative forcing from aerosol–cloud interactions, with the choice of aerosol proxy driving the overall uncertainty. The results are summarised into recommendations for using MODIS Nd products and appropriate sampling.

Edward Gryspeerdt↗

Influence of the Mediterranean outflow on the isotopic composition of neodymium in waters of the North Atlantic

Measurements of the Nd-143/Nd-144 ratio, expressed as epsilon-Nd(0), made in sea water samples obtained at depths from 0 to 4850 m at stations 95, 101, and 30 of North-Atlantic cruise 109-1 of the RV Atlantis II are reported and analyzed. In the 1000-m sample at station 95, determined by salinity, O2, PO4, NO3, SiO2, potential-temperature, and pressure profiles to correspond to the core of the Mediterranean outflow, an epsilon-Nd(0) value of -9.8 + or - 0.6 was found, a significant increase over the layers above and below, where epsilon-Nd(0) is about -12. Mixing estimations give a value for pure Mediterranean waters of approximately -6; continental drainage or volcanic deep-sea sediments are considered possible sources for this more radiogenic Nd. The epsilon-Nd(0) peak in the western North Atlantic (station 30) is found at the surface, and the deep waters are less radiogenic than in the eastern North Atlantic, suggesting multiple Nd sources. Possible origins and distribution mechanisms are discussed.

Piepgras, D. J.↗

Strontium and neodymium isotopes in hot springs on the East Pacific Rise and Guaymas Basin

Solutions collected from 21 deg N, East Pacific Rise (Epr) and Guaymas Basin, Gulf of California, are analyzed for Nd isotopic composition and Sm and Nd concentrations. The results indicate extensive but not complete isotopic exchange with Sr in the depleted oceanic crust and that Sr concentrations in these solutions are buffered. In contrast, the Nd data exhibit a wide range in isotopic composition and concentration between vents. Many samples show substantial contributions from MORB, but all have isotopic compositions below MORB, in spite of enrichments in Nd up to 100 times seawater. It is shown that the fluids must exchange Nd with a sedimentary reservoir having an isotopic composition less than Pacific seawater. Low-temperature reactions with metalliferous sediments on the flanks of the EPR may provide such a source. Using a simple box method, estimates of the hydrothermal fluxes of Nd are compared to fluxes which are necessary to maintain a radiogenic isotopic composition of about -3 in the Pacific against the influx of Antarctic waters. It is concluded that erosion from island arcs is the main source of radiogenic Nd in the Pacific.

Piepgras, D. J.↗

Direct solar-pumped iodine laser amplifier

This semiannual progress report covers the period from March 1, 1987 to September 30, 1987 under NASA grant NAG1-441 entitled 'Direct solar-pumped iodine laser amplifier'. During this period Nd:YAG and Nd:Cr:GSGG crystals have been tested for the solar-simulator pumped cw laser, and loss mechanisms of the laser output power in a flashlamp-pumped iodine laser also have been identified theoretically. It was observed that the threshold pump-beam intensities for both Nd:YAG and Nd:Cr:GSGG crystals were about 1000 solar constants, and the cw laser operation of the Nd:Cr:GSGG crystal was more difficult than that of the Nd:YAG crystal under the solar-simulator pumping. The possibility of the Nd:Cr:GSGG laser operation with a fast continuously chopped pumping was also observed. In addition, good agreement between the theoretical calculations and the experimental data on the loss mechanisms of a flashlamp-pumped iodine laser at various fill pressures and various lasants was achieved.

Han, Kwang S.↗

Direct solar-pumped iodine laser amplifier

A XeCl laser pumped iodine laser oscillator was developed which will be incorporated into the Master Oscillator Power Amplifier (MOPA) system. The developed XeCl laser produces output energy of about 60 mJ per pulse. The pulse duration was about 10 nsec. The kinetic model for the solar-pumped laser was refined and the algorithm for the calculation of a set of rate equations was improved to increase the accuracy and the efficiency of the calculation. The improved algorithm was applied to explain the existing experimental data taken from a flashlamp pumped iodine laser for three kinds of lasants, i-C3F7I, n-C4F9I, and t-C4F9I. Various solid laser materials were evaluated for solar-pumping. The materials studied were Nd:YAG, Nd:YLF, and Cr:Nd:GSGG crystals. The slope efficiency of 0.17 percent was measured for the Nd:YLF near the threshold pump intensity which was 211 solar constants (29W/sq cm). The threshold pump intensity of the Nd:YAG was measured to be 236 solar constants (32W/sq cm) and the near-threshold slope efficiency was 0.12 percent. True CW laser operation of Cr:Nd:GSGG was possible only at pump intensities less than or equal to 1,500 solar constants (203 W/sq cm). This fact was attributed to the high thermal focusing effect of the Cr:Nd:GSGG rod.

Han, Kwang S.↗

A modified pump laser system to pump the titanium sapphire laser

As a result of the wide tunability of the titanium sapphire laser NASA has sited it to be used to perform differential absorption lidar (DIAL) measurements of H2O vapor in the upper and lower troposphere. The titanium sapphire laser can provide a spectrally narrow (0.3 to 1.0 pm), high energy (0.5 to 1.0 J) output at 727, 762, and 940 nm which are needed in the DIAL experiments. This laser performance can be obtained by addressing the line-narrowing issues in a master oscillator and the high energy requirement in a fundamental mode oscillator. By injection seeding, the single frequency property of the master oscillator can produce a line narrow high energy power oscillator. A breadboard model of the titanium sapphire laser that will ultimately be used in NASA lidar atmospheric sensing experiment is being designed. The task was to identify and solve any problem that would arise in the actual laser system. One such problem was encountered in the pump laser system. The pump laser that is designed to pump both the master oscillator and power oscillator is a Nd:YLF laser. Nd:YLF exhibits a number of properties which renders this material an attractive option to be used in the laser system. The Nd:YLF crystal is effectively athermal; it produces essentially no thermal lensing and thermally induced birefringence is generally insignificant in comparison to the material birefringence resulting from the uniaxial crystal structure. However, in application repeated fracturing of these laser rods was experience. Because Nd:YLF rods are not commercially available at the sizes needed for this application a modified pump laser system to replace the Nd:YLF laser rod was designed to include the more durable Nd:YAG laser rods. In this design, compensation for the thermal lensing effect that is introduced because of the Nd:YAG laser rods is included.

Petway, Larry B.↗

Long-Lifetime Laser Materials For Effective Diode Pumping

Long quantum lifetimes reduce number of diodes required to pump. Pumping by laser diodes demonstrated with such common Nd laser materials as neodymium:yttrium aluminum garnet (Nd:YAG) and Nd:YLiF4, but such materials as Nd:LaF3, Nd:NaF.9YF3, and possibly Nd:YF3 more useful because of long lifetimes of their upper laser energy levels. Cost effectiveness primary advantage of solid-state laser materials having longer upper-laser-level lifetimes. Because cost of diodes outweighs cost of laser material by perhaps two orders of magnitude, cost reduced significantly.

Barnes, Norman P.↗

Pre-bombardment crystallization ages of basaltic clasts from Antarctic howardites EET87503 and EET87513

Igneous clasts of basaltic eucrites are found in both howardites and polymict eucrites. We have studied the Rb-Sr and Sm-Nd isotopic systematics of a number of such clasts, of metamorphic grades 1-6, using the classification of Takeda and Graham. Here, we report Rb-Sr, (147)Sm-(143)Nd, and (145)Sm-(142)Nd studies of clast, 53 from Antarctic howardite EET87503. Although there is no evidence of disturbance of trace element systematics by Antarctic weathering, the Rb-Sr and conventional Sm-Nd isotopic systematics are severely disturbed, which we ascribe to thermal metamorphism. The Ar-Ar age spectrum shows ages ranging from approximately 3.85-3.55 Ga in an unusual 'down stairstep'. The (146)Sm-(142)Nd systematics, however, show the presence of live (146)Sm(t(sub 1/2) = 103 Ma), with (146)Sm/(144)Sm = 0.0061 +/- 0.0007 at the time of crystallization. This result is very similar to that previously obtained for basaltic clast, 18 from howardite EET87513 (paired with EET87503), which has concordant Rb-Sr and Sm-Nd ages of approximately 4.5 Ga. Thus, the two clasts are nearly the same age, and we conclude further than the EET87503,53 clast crystallized within 33 +/- 19 Ma of the LEW86010 angrite by comparing initial (146)Sm/(144)Sm to that of the angrite. We suggest that disturbances in the isotopic systematics of EET87503,53 are consanguineous with pyroxene homogenization.

Nyquist, L. E.↗

Kinematics and Kinetics of Squat and Deadlift Exercises with Varying Stance Widths

The primary motion of squat and deadlift exercise involves flexion and extension of the hips, knees, and ankles, but each exercise can be performed with variations in stance width. These variations may result in differing kinematics and ground reaction forces (GRF), which may in turn affect joint loading. PURPOSE: The purpose of this investigation was to compare ankle, knee, and hip kinematics and kinetics of normal squat (NS), wide-stance squat (WS), normal deadlift (ND), and sumo deadlift (SD). We hypothesized that hip joint kinematics and work at each joint would differ between exercise variations. METHODS: Six subjects (3 m/3 f; 70.0 plus or minus 13.7 kg; 168 plus or minus 9.9 cm) performed each lift in normal gravity on the ground-based version of the Advanced Resistive Exercise Device (ARED) used on the International Space Station. The ARED provided resistance with a combination vacuum tube/flywheel mechanism designed to replicate the gravitational and inertial forces of free weights. Subjects completed each lift with their 10-repetition maximum load. Kinematic data were collected at 250 Hz by a 12-camera motion-capture system (Smart-D, BTS Bioengineering, Milan, Italy), and GRF data were collected at 1000 Hz with independent force platforms for each leg (Model 9261, Kistler Instruments AG, Winterhur, Switzerland). All data were captured simultaneously on a single workstation. The right leg of a single lift for each motion was analyzed. Modeling software (OpenSim 2.2.0, Simbios, Palo Alto, CA) determined joint kinematics and net positive and negative work at each lower extremity joint. Total work was found as the sum of work across all joints and was normalized by system mass. Effect sizes and their 95% confidence intervals were computed between conditions. RESULTS: Peak GRF were similar for each lift. There were no differences between conditions in hip flexion range of motion (ROM). For hip adduction ROM, there were no differences between the NS, WS, and SD. However, hip adduction ROM was greater during the NS and SD than during the ND. Hip rotation ROM was greater during the WS than during the NS and SD, and was greater during the SD than during the ND. For knee and ankle flexion ROM, the ND, WS, and SD were not different, but ROM was greater during the NS than the ND and greater during the WS than the SD. Total eccentric work was greater during the WS than the SD. Otherwise, there were no differences in eccentric or concentric work between conditions. CONCLUSIONS: Although squat and deadlift exercises consist of similar motions, there are kinematic differences between them that depend on stance width. Total eccentric and concentric work are similar for different lifts, but differing kinematics may require activation of different musculature for each variation. With respect to each condition, in the ND the ROM of each joint tended to be less, and the WS tended to trade knee motion for hip motion. PRACTICAL APPLICATIONS: Knowledge of differences in kinematics and kinetics between different squat and deadlift variations is important for coaches and rehabilitation personnel to understand when prescribing exercise. Our results suggest that each variation of the squat and deadlift should be considered a separate exercise that may induce different long-term training effects.

DeWitt, John K.↗

Constraining the Twomey effect from satellite observations: Issues and perspectives

The Twomey effect describes the radiative forcing associated with a change in cloud albedo due to an increase in anthropogenic aerosol emissions. It is driven by the perturbation in cloud droplet number concentration (ΔNd,ant) in liquid-water clouds and is currently understood to exert a cooling effect on climate. The Twomey effect is the key driver in the effective radiative forcing due to aerosol–cloud interactions which also comprises rapid adjustments. These adjustments are essentially the responses of cloud fraction and liquid water path to ΔNd,ant and thus scale approximately with it. While the fundamental physics of the influence of added aerosol particles on the droplet concentration (Nd) is well described by established theory at the particle scale (micrometres), how this relationship is expressed at the large scale (hundreds of kilometres) ΔNd,ant remains uncertain. The discrepancy between process understanding at particle scale and insufficient quantification at the climate-relevant large scale is caused by co-variability of aerosol particles and vertical wind and by droplet sink processes. These operate at scales on the order of 10s of metres at which only localized observations are available and at which no approach exists yet to quantify the anthropogenic perturbation. Different atmospheric models suggest diverse magnitudes of the Twomey effect even when applying the same anthropogenic aerosol emission perturbation. Thus, observational data are needed to quantify and constrain the Twomey effect. At the global scale, this means satellite data. There are three key uncertainties in determining ΔNd,ant, namely the quantification (i) of the cloud-active aerosol – the cloud condensation nuclei concentrations (CCN) at or above cloud base –, (ii) of Nd, as well as (iii) the statistical approach for inferring the sensitivity of Nd to aerosol particles from the satellite data. A fourth uncertainty, the anthropogenic perturbation to CCN concentrations, is also not easily accessible from observational data. This review discusses deficiencies of current approaches for the different aspects of the problem and proposes several ways forward: In terms of CCN, retrievals of optical quantities such as aerosol optical depth suffer from a lack of vertical resolution, size and hygroscopicity information, the non-direct relation to the concentration of aerosols, the impossibility to quantify it within or below clouds, and the problem of insufficient sensitivity at low concentrations, in addition to retrieval errors. A future path forward can include utilizing colocated polarimeter and lidar instruments, ideally including high spectral resolution lidar capability at two wavelengths to maximize vertically resolved size distribution information content. In terms of Nd, a key problem is the lack of operational retrievals of this quantity, and the inaccuracy of the retrieval especially in broken-cloud regimes. As for the Nd – to – CCN sensitivity, key issues are the updraught distributions and the role of Nd sink processes, for which empirical assessments for specific cloud regimes are currently the best solutions. These considerations point to the conclusion that past studies using existing approaches have likely underestimated the true sensitivity and, thus, the radiative forcing due to the Twomey effect.

Twomey effect↗

Neodymium isotopic variations in seawater

Direct measurement of the isotopic composition of Nd in the Atlantic agree with the Nd content in ferromanganese sediments and differ from the observed amounts in the Pacific samples. These data indicate the existence of distinctive differences in the isotopic composition of Nd in the waters of major oceans; the average values determined from seawater and ferromanganese sediments are considerably lower than in sources with oceanic mantle affinities showing that the REE in the oceans is dominated by continental sources. The Nd isotopic variations in seawater are applied to relate the residence time of Nd and mixing rates between the oceans.

Piepgras, D. J.↗

Solid-state laser sources for remote sensing

Recent progress in slab-geometry and conventional rod Nd:YAG solid-state lasers for applications in remote sensing is presented. Developments in slab geometry lasers, which were aimed at improving pulse energy and tuning range, have been based on the use of a Nd:glass substrate with a zig-zag optical path, with selective Raman shifting in gases and harmonic generation in LiNbO3 and KDP to extend the tuning range into the UV and visible regions. The theoretically predicted advantages of the elimination of birefringence and thermal and stress-induced focusing in the slab-geometry laser have been confirmed in measurements on a test-bed Nd:glass system, and a CW lamp pumped Nd:YAG oscillator, which have also demonstrated an order of magnitude improvement in laser performance. A single axial mode Nd:YAG oscillator has also been designed which, operating in a 3-msec quasi-CW mode, has a chirp rate of 30 kHz/microsec and a free-running stability of + or - 20 MHz. With chirp compensation, this stability is adequate for wind velocity measurements by coherent lidar.

Byer, R. L.↗