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At least 307 records · Page 17

Effect of hydrogen on the mechanical properties of titanium and its alloys

Occluded hydrogen resulting from cathodic charging of commercially pure titanium and titanium alloys, Ti-8Al-1Mo-1V and Ti-6Al-4V, was shown to cause embrittlement of the alloys. Embrittlement was a function of the interstitial hydrogen content rather than the amount of precipitated titanium hydride. The effects of hydrogen concentration on the critical strain for plastic instability along pure shear directions was determined for alloys Ti-8Al-1Mo-1V and Ti-5Al-2.5Sn. Hydrogen, in concentrations below that necessary for spontaneous hydride precipitation, increased the strain necessary for instability formation or instability failure. The strain rate sensitivity also increased with increasing hydrogen concentration. The effect of hydrogen on slip and twinning was determined for titanium single crystals. The critical resolved shear stress for prism slip was increased and the critical resolved shear stress for twinning was decreased with increasing hydrogen concentration.

Beck, F. H.↗

Response Of Mineralizing And Non-Mineralizing Bone Cells To Fluid Flow: An In Vitro Model For Mechanotransruction

Humans reach peak bone mass at age 30. After this point, we lose 1 to 2 percent of bone mass each decade. In the microgravity environment of space, astronauts lose bone mass at an accelerated rate of 1 to 2 percent each month. When astronauts travel to Mars, they may be in space for as long as 3 years. During this time, they may lose about half of their bone mass from weight-bearing bones. This loss may be irreversible. The drastic loss in bone that astronauts experience in space makes them much more vulnerable to fractures. In addition, the corresponding removal of calcium from bone results in higher levels of calcium in the blood, which increases the risk of developing kidney stones. Currently, studies are being conducted which investigate factors governing bone adaptation and mechanotransduction. Bone is constantly adapting in response to mechanical stimuli. Increased mechanical loading stimulates bone formation and suppresses bone resorption. Reduction in mechanical loading caused by bedrest, disuse, or microgravity results in decreased bone formation and possibly increased bone resorption. Osteoblasts and osteoclasts are the two main cell types that participate in bone remodeling. Osteoblasts are anabolic (bone-forming) cells and osteoclasts are catabolic (bone-resorbing) cells. In microgravity, the activity of osteoblasts slows down and the activity of osteoclasts may speed up, causing a loss of bone density. Mechanotransduction, the molecular mechanism by which mechanical stimuli are converted to biochemical signals, is not yet understood. Exposure of cells to fluid flow imposes a shear stress on the cells. Several studies have shown that the shear stress that results from fluid flow induces a cellular response similar to that induced by mechanical loading. Thus, fluid flow can be used as an in vitro model to simulate the mechanical stress that bone cells experience in vivo. Previous in vitro studies have shown that fluid flow induces several responses in osteoblasts, including increased proliferation, osteoblastic differentiation, alkaline phosphatase activity, and production of nitric oxide, prostaglandins, and osteopontin. Several proteins have been implicated in osteoblastic mechanotransduction including Bone Morphogenetic Protein-2 (BMP-2), parathyroid hormone, 1,25-dihydroxyvitamin D3 receptor, osteopontin (OPN), osteoprotegerin (OPG), and alkaline phosphatase (AP). We will characterize relative levels of each protein in mineralizing or non-mineralizing MC3T3 osteoblastic cells that have been exposed to fluid flow compared to non-fluid flow using immunofluorescent staining and two- photon laser microscopy as well as western blotting. Because calcium-mediated pathways are important in osteoblastic signaling, we will transfect MC3T3 cells with cameleon probes for Ca2+ containing YFP and CFP. Results will be analyzed using FRET/FLIM to study differential release of intracellular Ca(2+) in response to fluid flow and conditions inducing matrix mineralization. In addition, we plan to conduct several microarray experiments to determine differential gene expression in MC3T3 cells in response to fluid flow and conditions inducing mineralization.

Makuch, Lauren A.↗

Numerical simulation of a three-dimensional turbulent boundary layer

The effects of transverse strain on an initially two-dimensional turbulent boundary layer are studied in a direct numerical simulation of a planar channel flow with impulsively started transverse pressure gradient. Consistent with experiments in three-dimensional boundary layers, the simulation shows a drop in the Reynolds shear stress with increasing transverse strain. Also, the directions of the Reynolds shear stress vector and the mean velocity gradient vector were found to differ. In addition, the simulation shows a drop in the turbulent kinetic energy. The terms in the budget of the Reynolds stress were computed. In general, the individual terms do not show a significant change. However, an increase in dissipation rate rather than reduction in total production appears to be responsible for the drop in turbulent kinetic energy.

Moin, P.↗

Direct numerical simulation of a three-dimensional turbulent boundary layer

The effects of transverse strain on an initially two-dimensional turbulent boundary layer are studied in a direct numerical simulation of a planar channel flow with impulsively started transverse pressure gradient. Consistent with experiments in three-dimensional boundary layers, the simulation shows a decrease in the Reynolds shear stress with increasing transverse strain. Also, the directions of the Reynolds shear stress vector and the mean velocity gradient vector were found to differ. In addition, the simulation shows a drop in the turbulent kinetic energy. Terms in the Reynolds stress transport equations were computed. The balances indicate that the decrease in turbulent kinetic energy is a result of a decrease in turbulence production, along with an increase in turbulent dissipation. Intuitive reasoning and current turbulence models would predict an increase in kinetic energy along with increases in production and dissipation rates as a result of increased mean-flow strain rate. Later in the evolution of the flow, both turbulence production and dissipation increase.

Moin, P.↗

Computation of turbulent boundary layers employing the defect wall-function method

In order to decrease overall computational time requirements of spatially-marching parabolized Navier-Stokes finite-difference computer code when applied to turbulent fluid flow, a wall-function methodology, originally proposed by R. Barnwell, was implemented. This numerical effort increases computational speed and calculates reasonably accurate wall shear stress spatial distributions and boundary-layer profiles. Since the wall shear stress is analytically determined from the wall-function model, the computational grid near the wall is not required to spatially resolve the laminar-viscous sublayer. Consequently, a substantially increased computational integration step size is achieved resulting in a considerable decrease in net computational time. This wall-function technique is demonstrated for adiabatic flat plate test cases from Mach 2 to Mach 8. These test cases are analytically verified employing: (1) Eckert reference method solutions, (2) experimental turbulent boundary-layer data of Mabey, and (3) finite-difference computational code solutions with fully resolved laminar-viscous sublayers. Additionally, results have been obtained for two pressure-gradient cases: (1) an adiabatic expansion corner and (2) an adiabatic compression corner.

Brown, Douglas L.↗

Influence of Thermocapillary Flow on Capillary Stability: Long Float-Zones in Low Gravity

A model problem is posed to study the influence of flow on the interfacial stability of a nearly cylindrical liquid bridge for lengths near its circumference (the Plateau-Rayleigh limit). The flow is generated by a shear stress imposed on the deformable interface. The symmetry of the imposed shear stress mimics the thermocapillary stress induced on a float-zone by a ring heater (i.e. a full zone). Principal assumptions are (1) zero gravity, (2) creeping flow, and (3) that the imposed coupling at the free surface between flow and temperature fields is the only such coupling. A numerical solution, complemented by a bifurcation analysis, shows that bridges substantially longer than the Plateau-Rayleigh limit are possible. An interaction of the first two capillary instabilities through the stress-induced flow is responsible. Time-periodic standing waves are also predicted in certain parameter ranges. Motivation comes from extra-long float-zones observed in MEPHISTO space lab experiments (June 1994).

Chen, Yi-Ju↗

Nitric oxide production by cultured human aortic smooth muscle cells: stimulation by fluid flow

This study demonstrated that exposure of cultured human aortic smooth muscle cells (SMC) to fluid flow resulted in nitric oxide (NO) production, monitored by nitrite and guanosine 3',5'-cyclic monophosphate production. A rapid burst in nitrite production rate was followed by a more gradual increase throughout the period of flow exposure. Neither the initial burst nor the prolonged nitrite production was dependent on the level of shear stress in the range of 1.1-25 dyn/cm2. Repeated exposure to shear stress after a 30-min static period restimulated nitrite production similar to the initial burst. Ca(2+)-calmodulin antagonists blocked the initial burst in nitrite release. An inhibitor of nitric oxide synthase (NOS) blocked nitrite production, indicating that changes in nitrite reflect NO production. Treatment with dexamethasone or cycloheximide had no effect on nitrite production. Monoclonal antibodies directed against the inducible and endothelial NOS isoforms showed no immunoreactivity on Western blots, whereas monoclonal antibodies directed against the neuronal NOS gave specific products. These findings suggest that human aortic SMC express a constitutive neuronal NOS isoform, the enzymatic activity of which is modulated by flow.

Non-NASA Center↗

Evaluation of Heat Transfer Coefficient from Velocity Distribution in Boundary Layer

This paper describes a method of evaluating heat transfer coefficient from a velocity distribution in the boundary layer. The power law velocity profile and universal velocity distribution in a smooth pipe have been used to evaluate the wall shear stress, and the heat transfer coefficient was evaluated from the wall shear stress using the Chilton-Colburn analogy. The predicted pressure drop was compared with the pressure drop computed by the Colebrook equation, and the predicted heat transfer coefficient was compared with the heat transfer coefficient calculated by the Dittus-Boelter equation. The accuracy of pressure drop prediction was within 1%, and the accuracy of heat transfer coefficient prediction was within 8%. This method has the potential to use a Navier-Stokes based CFD solution to evaluate the heat transfer coefficient in nodal or network flow codes.

Heat Transfer Coefficient↗

Evaluation of Heat Transfer Coefficient from Velocity Distribution in Boundary Layer

This paper describes a method of evaluating heat transfer coefficient from a velocity distribution in the boundary layer. The power law velocity profile and universal velocity distribution in a smooth pipe have been used to evaluate the wall shear stress, and the heat transfer coefficient was evaluated from the wall shear stress using the Chilton-Colburn analogy. The predicted pressure drop was compared with the pressure drop computed by the Colebrook equation, and the predicted heat transfer coefficient was compared with the heat transfer coefficient calculated by the Dittus-Boelter equation. The accuracy of pressure drop prediction was within 1%, and the accuracy of heat transfer coefficient prediction was within 8%. This method has the potential to use a Navier-Stokes based CFD solution to evaluate the heat transfer coefficient in nodal or network flow codes.

Heat Transfer Coefficient↗

Microbial Responses to Microgravity and Other Low-Shear Environments

Microbial adaptation to environmental stimuli is essential for survival. While several of these stimuli have been studied in detail, recent studies have demonstrated an important role for a novel environmental parameter in which microgravity and the low fluid shear dynamics associated with microgravity globally regulate microbial gene expression, physiology, and pathogenesis. In addition to analyzing fundamental questions about microbial responses to spaceflight, these studies have demonstrated important applications for microbial responses to a ground-based, low-shear stress environment similar to that encountered during spaceflight. Moreover, the low-shear growth environment sensed by microbes during microgravity of spaceflight and during ground-based microgravity analogue culture is relevant to those encountered during their natural life cycles on Earth. While no mechanism has been clearly defined to explain how the mechanical force of fluid shear transmits intracellular signals to microbial cells at the molecular level, the fact that cross talk exists between microbial signal transduction systems holds intriguing possibilities that future studies might reveal common mechanotransduction themes between these systems and those used to sense and respond to low-shear stress and changes in gravitation forces. The study of microbial mechanotransduction may identify common conserved mechanisms used by cells to perceive changes in mechanical and/or physical forces, and it has the potential to provide valuable insight for understanding mechanosensing mechanisms in higher organisms. This review summarizes recent and future research trends aimed at understanding the dynamic effects of changes in the mechanical forces that occur in microgravity and other low-shear environments on a wide variety of important microbial parameters.

Review↗

Strengthening mechanisms for microstructures containing unimodal and bimodal γ' precipitates in ATI 718Plus

Here, the influence of γ' precipitate size distribution on the deformation mechanisms under tensile loading in ATI 718Plus was studied. A set of aging treatments within the temperature range of 720 °C–900 °C was performed on solution-treated samples to obtain various γ' precipitate size distributions. Unimodal and bimodal γ' precipitate size distributions were achieved through single-step and two-step aging sequences, respectively, and such microstructures were tensile tested to failure to assess their yield strength, ultimate tensile strength, and elongation-to-failure. Some of the tensile samples were interrupted after achieving 3–4 % plastic strain, and the deformed microstructures were examined using transmission electron microscopy to investigate the γ' precipitate-dislocation interactions. For the unimodal γ' precipitate size distribution samples with the smaller γ' precipitates (radius ~ 7 nm), dislocations sheared through the precipitates. Both dislocation loops and paired dislocations were observed for the microstructures containing larger γ' precipitates (radius ~ 24 nm). The microstructure containing a bimodal γ' precipitate size distribution, which included average γ' precipitate radii of ~6 nm and ~28 nm, exhibited shearing as the dominant deformation mechanism, and this microstructure exhibited the highest strength values. The experimental observations were rationalized based on the theoretically-calculated critical resolved shear stress values for shearing and looping and a modified model for predicting the yield strength for bimodal microstructures was introduced.

36 MATERIALS SCIENCE↗

Identification of mechanisms driving heterogeneous void growth in ductile aluminum

Void growth plays a central role in ductile fracture, yet the specific mechanisms that control this remain obscure. Classical models, such as those proposed by Rice and Tracey in 1969, are able to capture average rates of void growth, but cannot capture the heterogeneity of individual void growth. Building on recent work, the present study employs laboratory-based diffraction contrast tomography and in-situ x-ray computed tomography to investigate the effect of grain structure and other microstructural factors on void growth in an Al-2219 alloy. Crystal plasticity finite element (CP-FE) modeling is used alongside experimental data to evaluate the contributions of local mechanical states, grain orientation, grain size, and neighboring microstructural features. No strong linear relationships are found with any of the considered descriptors and void growth rate. Potential complex nonlinear relationships are explored with the use of a random forest regression model, which identifies initial void volume, void aspect ratio, local normal stress state, local shear stress state, and local equivalent plastic strain (EQPS) as features that most improve void growth rate predictions. The combination of these analyses suggests that these features should be prioritized to improve models of void growth.

Diffraction contrast tomography (DCT)↗

Investigation of smooth specimen scc test procedures; variations in environment, specimen size, stressing frame, and stress state

The variables studied in the stress-corrosion cracking performance of high strength aluminum alloys were: (1) corrosiveness of the environment, (2) specimen size and stiffness of the stressing system, (3) interpretation of transgranular cracking, and (4) interaction of the state of stress and specimen orientation in a product with an anisotropic grain structure. It was shown that the probability of failure and time to fracture for a specimen loaded in direct tension are influenced by corrosion pattern, the stressing assembly stiffness, and the notch tensile strength of the alloy. Results demonstrate that the combination of a normal tension stress and a shear stress acting on the plane of maximum susceptibility in a product with a highly directional grain cause the greatest tendency for stress-corrosion cracking.

Lifka, B. W.↗

Fatigue of notched fiber composite laminates. Part 1: Analytical model

A description is given of a semi-empirical, deterministic analysis for prediction and correlation of fatigue crack growth, residual strength, and fatigue lifetime for fiber composite laminates containing notches (holes). The failure model used for the analysis is based upon composite heterogeneous behavior and experimentally observed failure modes under both static and fatigue loading. The analysis is consistent with the wearout philosophy. Axial cracking and transverse cracking failure modes are treated together in the analysis. Cracking off-axis is handled by making a modification to the axial cracking analysis. The analysis predicts notched laminate failure from unidirectional material fatique properties using constant strain laminate analysis techniques. For multidirectional laminates, it is necessary to know lamina fatique behavior under axial normal stress, transverse normal stress and axial shear stress. Examples of the analysis method are given.

Mclaughlin, P. V., Jr.↗

Several intact or broken stringers attached to an orthotropic sheet with a crack

Several intact or broken stringers which are continuously attached to a cracked orthotropic sheet through an adhesive are considered. The effect of orthotropy on the stress intensity factors is investigated. The stringers are assumed to be partially debonded due to high stress concentrations. The shear stress distribution between the stringers and the plate and the stress intensity factors are obtained from an integral equation which represents the continuity of displacements along the bond lines.

Arin, K.↗

Generalized velocities in the outer region of hypersonic turbulent boundary layers

An attempt is made to show that the outer portion of the velocity profile of hypersonic turbulent boundary layers can be transformed so that the constants determined by a best fit to the law of the wake are in reasonable agreement with the wake constant for incompressible boundary layers at the same Reynolds number. Both y transformations (where y is distance from the surface) and velocity transformations produce velocity profiles which, with the proper choice of wall shear stress to give shear velocity, can be reduced to the incompressible law of the wall.

Watson, R. D.↗

Three-dimensional analysis of 0/90s and 90/0s laminates with a central circular hole

Stress distributions were calculated near a circular hole in laminates, using a three dimensional finite element analysis. These stress distributions were presented three ways: through the thickness at the hole boundary, along radial lines at the 0/90 and 90/0 interfaces, and around the hole at these interfaces. The interlaminar normal stress, and the shear stress, distributions had very steep gradients near the hole boundary, suggesting interlaminar stress singularities. The largest compressive stress occurred at about 60 deg from the load axis. A simple procedure was introduced to calculate interlaminar stresses near the hole boundary. It used stresses calculated by an exact two dimensional analysis of a laminate with a hole as input to a quasi three dimensional model. It produced stresses that agreed closely with those from the three dimensional finite element model.

Raju, I. S.↗

Impact-induced fracture in a quasi-isotropic laminate

A systematic study of impact-induced fracture in a quasi-isotropic laminated composite is carried out. The main focus of the study is to understand damage initiation when a laminate is subjected to the impact of a foreign object. The total incipient damage of a laminate subjected to impact at higher than threshold velocity is also presented. The incipient damage is restricted to small growth from the initiation of the damage. The experimentally collected data are interpreted using a two-dimensional plane-strain finite-element analysis. The qualitative comparison suggests that the skew cracks in the proximal layers are primarily due to transverse shear stress. Skew cracks in the middle layers are also due to transverse shear stress. Vertical cracks in the distal layer are due to flexural stress transverse to the fiber orientation of the layer.

Joshi, S. P.↗