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At least 307 records · Page 17

A bioactive supramolecular and covalent polymer scaffold for cartilage repair in a sheep model

Regeneration of hyaline cartilage in human-sized joints remains a clinical challenge, and it is a critical unmet need that would contribute to longer healthspans. Injectable scaffolds for cartilage repair that integrate both bioactivity and sufficiently robust physical properties to withstand joint stresses offer a promising strategy. We report here on a hybrid biomaterial that combines a bioactive peptide amphiphile supramolecular polymer that specifically binds the chondrogenic cytokine transforming growth factor β-1 (TGFβ-1) and crosslinked hyaluronic acid microgels that drive formation of filament bundles, a hierarchical motif common in natural musculoskeletal tissues. The scaffold is an injectable slurry that generates a porous rubbery material when exposed to calcium ions once placed in cartilage defects. The hybrid material was found to support in vitro chondrogenic differentiation of encapsulated stem cells in response to sustained delivery of TGFβ-1. Using a sheep model, we implanted the scaffold in shallow osteochondral defects and found it can remain localized in mechanically active joints. Evaluation of resected joints showed significantly improved repair of hyaline cartilage in osteochondral defects injected with the scaffold relative to defects injected with the growth factor alone, including implantation in the load-bearing femoral condyle. These results demonstrate the potential of the hybrid biomimetic scaffold as a niche to favor cartilage repair in mechanically active joints using a clinically relevant large-animal model.

Science & Technology - Other Topics↗

Dynamic verification of very large space structures

The dynamic verification of spacecraft relies heavily on ground-based tests. These tests usually simulate flight environments or validate analytical models used in establishing design loads and in designing control algorithms. They also provide security against failures resulting from unanticipated or unmodeled hardware behavior. Future orbital antennas, space stations, and solar power systems are likely to be of sizes difficult to test using current ground test technology. In addition to size, other factors such as low natural frequencies, lightweight construction, and the presence of many structural joints, cause significant sensitivity of the test process to the earth-gravity environment. Yet, accuracy requirements on the verification process will be more stringent because of modern flexible-structure control approaches. This paper describes some of the problems and discusses research on potential solutions. The importance of an integrated ground test, analysis, and flight test program is emphasized. An ongoing research program of this type focusing on a 60-meter, deployable, truss-beam test article is described.

Hanks, B. R.↗

A coupled fluid-structure dynamic analysis for water impact loads

In this paper a nonlinear transient, hydroelastic method is developed for response analysis of the Space Shuttle recoverable booster on water impact. At each time step, coupled equations of fluid flow and structure dynamics are solved with an iterative, self-correcting process. Rigid body motions are represented by large angle equations. Local deformations are represented by a NASTRAN-generated model of the three-dimensional structure. The fluid is represented by series solutions of the potential flow equation which include the effects of the local structure motions. The resulting water loads and structural stresses obtained will aid in qualification of the final structural design. Comparisons are made to experimental impact data to validate the method.

Herting, D. N.↗

Simulating Vibrations in a Complex Loaded Structure

The Dynamic Response Computation (DIRECT) computer program simulates vibrations induced in a complex structure by applied dynamic loads. Developed to enable rapid analysis of launch- and landing- induced vibrations and stresses in a space shuttle, DIRECT also can be used to analyze dynamic responses of other structures - for example, the response of a building to an earthquake, or the response of an oil-drilling platform and attached tanks to large ocean waves. For a space-shuttle simulation, the required input to DIRECT includes mathematical models of the space shuttle and its payloads, and a set of forcing functions that simulates launch and landing loads. DIRECT can accommodate multiple levels of payload attachment and substructure as well as nonlinear dynamic responses of structural interfaces. DIRECT combines the shuttle and payload models into a single structural model, to which the forcing functions are then applied. The resulting equations of motion are reduced to an optimum set and decoupled into a unique format for simulating dynamics. During the simulation, maximum vibrations, loads, and stresses are monitored and recorded for subsequent analysis to identify structural deficiencies in the shuttle and/or payloads.

Cao, Tim T.↗

Large-Scale Simulations and Detailed Flow Field Measurements for Turbomachinery Aeroacoustics

The presentation is a review of recent work in highly loaded compressors, turbine aeroacoustics and cooling fan noise. The specific topics are: the importance of correct numerical modeling to capture blade row interactions in the Ultra Efficient Engine Technology Proof-of-Concept Compressor, the attenuation of a detonation pressure wave by an aircraft axial turbine stage, current work on noise sources and acoustic attenuation in turbines, and technology development work on cooling fans for spaceflight applications. The topic areas were related to each other by certain themes such as the advantage of an experimentalist s viewpoint when analyzing numerical simulations and the need to improve analysis methods for very large numerical datasets.

VanZante, Dale↗

A study of some approximations in the modeling of a coupled rotor/fuselage aeromechanical system

Equations of motion for a three-bladed hingeless rotor coupled to a gimbal-supported fuselage are developed. A brief derivation of the equations is presented, including the assumptions made, the ordering scheme, and a discussion of both the source of the aerodynamic axial load term and the reason for differences due to hinge sequence. The solution of the equations is discussed, including linearization, the use of multiblade coordinates to eliminate periodic coefficients, and specialization to a root-sprung model. The treatment of the blade root offset by using an ordering scheme to neglect higher-order terms is found to affect results in pitch and roll. A small aerodynamic loading term in the blade axial direction has a significant effect at large collective pitch settings, as does the choice of a flap-lag or a lag-flap transformation sequence for blade motion. The results for a hingeless rotor also differ significantly from those for the root-sprung model when the nonrotating natural frequencies are matched.

Blelloch, P. A.↗

Data from a Static-Thrust Investigation of Large-Scale General Research VTOL-STOL Model in Ground Effect

The model was tested at two different elevations with the wing pivot at 1.008 and 2.425 propeller diameters above the ground. The slipstream of the propellers was deflected by tilting the wing and propellers, by deflections of large-chord trailing-edge flaps, and by combinations of flap deflection and wing tilt. Tests were conducted over a range of propeller disk loadings from 7.41 to 29.70 pounds per square foot. Force data for the complete model and pressure distributions for the wing and flaps behind one propeller were recorded and are presented in tabular form without analysis.

Huston, Robert J.↗

Scaling Of Responses Of Composite Beams

Report describes series of experiments in which scale-model composite beams made of matrix/fiber composite materials tested to failure under combined axial compressive and bending loads. Discusses scaling effects in static large-deflection response of composite beams.

Jackson, Karen E.↗

The Pressure Distribution over the Horizontal Tail Surfaces of an Airplane II

This investigation was undertaken to determine whether the results obtained upon model tail surfaces can be used to accurately predict loads upon the full-sized tail; and also to find the distribution of load when large elevator angles are used, as the loads from such angles can not be obtained readily in free flight. The method consisted in using a metal horizontal tail surface inside of which small air passages, connecting with a series of holes in the surface, led the pressure off from the tail in rubber tubes. In this way the pressure at each of these holes was measured by a manometer at several angles of attack and several to the loading under similar conditions in the full-sized airplane and the manner of distribution is quite similar in the two cases when there is no slip stream.

Norton, F H↗

Investigation of Interference of a Deflected Jet with Free Stream and Ground on Aerodynamic Characteristics of a Semispan Delta-Wing VTOL Model

An investigation of the mutual interference effects of the ground, wing, deflected jet stream, and free stream of a semispan delta-wing VTOL model at zero and low forward speeds has been conducted in the 17-foot test section of the Langley 300-MPH 7-by 10-foot tunnel. The model consisted of two interchangeable semispan clipped delta wings, a simplified fuselage, and a high-pressure jet for simulation of a jet exhaust. Attached to the wing behind the jet were various sets of vanes for deflecting the jet stream to different turning angles. The effect of ground proximity gave the normally expected losses in lift at zero and very low forward speeds (up to about 60 or 80 knots for the assumed wing loading of 100 lb/sq ft); at higher forward speeds ground effects were favorable. At low forward speeds, out of ground effect, the model encountered large losses in lift and large nose-up pitching moments with the model at low angles of attack and the jet deflected 90 deg or 75 deg (the angles required for VTOL performance and very low forward speeds). Rotating the model to higher angles of attack and deflecting the jet back to lower angles eliminated these losses in lift. Moving the jet rearward with respect to the wing reduced the losses in lift and the nose-up moments at all speeds within the range of this investigation.

Spreemann, Kenneth P.↗

A Finite Element Analysis for Predicting the Residual Compressive Strength of Impact-Damaged Sandwich Panels

A simple analysis method has been developed for predicting the residual compressive strength of impact-damaged sandwich panels. The method is tailored for honeycomb core-based sandwich specimens that exhibit an indentation growth failure mode under axial compressive loading, which is driven largely by the crushing behavior of the core material. The analysis method is in the form of a finite element model, where the impact-damaged facesheet is represented using shell elements and the core material is represented using spring elements, aligned in the thickness direction of the core. The nonlinear crush response of the core material used in the analysis is based on data from flatwise compression tests. A comparison with a previous analysis method and some experimental data shows good agreement with results from this new approach.

Ratcliffe, James G.↗

A Finite Element Analysis for Predicting the Residual Compression Strength of Impact-Damaged Sandwich Panels

A simple analysis method has been developed for predicting the residual compression strength of impact-damaged sandwich panels. The method is tailored for honeycomb core-based sandwich specimens that exhibit an indentation growth failure mode under axial compression loading, which is driven largely by the crushing behavior of the core material. The analysis method is in the form of a finite element model, where the impact-damaged facesheet is represented using shell elements and the core material is represented using spring elements, aligned in the thickness direction of the core. The nonlinear crush response of the core material used in the analysis is based on data from flatwise compression tests. A comparison with a previous analysis method and some experimental data shows good agreement with results from this new approach.

Ratcliffe, James G.↗

Real Time Fatigue Damage Growth Assessment of a Composite Three-Stringer Panel Using Passive Thermography

Fatigue testing of advanced composite structures is critical to validate both structural designs and damage prediction models. In-situ inspection methods are necessary to track damage onset and growth as a function of load cycles. Passive thermography is a large area, noncontact inspection technique that is used to detect composite damage onset and growth in real time as a function of fatigue cycles. The thermal images are acquired in synchronicity to the applied compressive load using a dual infrared camera acquisition system for full (front and back) coverage. Image processing algorithms are investigated to increase defect contrast areas. The thermal results are compared to non-immersion ultrasound inspections and acoustic emission data.

Zalameda, Joseph N.↗

Less Atmospheric Radiative Heating By Dust Due to the Synergy of Coarser Size and Aspherical Shape

Mineral dust aerosols cool and warm the atmosphere by scattering and absorbing solar (shortwave: SW) and thermal (longwave: LW) radiation. However, significant uncertainties remain in dust radiative effects, largely due to differences in the dust size distribution and spectral optical properties simulated in Earth system models. Dust models typically underestimate the coarse dust load (more than 2.5 µm in diameter) and assume a spherical shape, which leads to an overestimate of the fine dust load (less than 2.5 µm) after the dust emissions in the models are scaled to match observed dust aerosol optical depth at 550 nm (DAOD550). Here, we improve the simulated dust properties with data sets that leverage measurements of size-resolved dust concentration, asphericity factor, and refractive index in a coupled global chemical transport model with a radiative transfer module. After the adjustment of size-resolved dust concentration and spectral optical properties, the global and annual average of DAOD550 from the simulation increases from 0.023 to 0.029 and falls within the range of a semi-observationally based estimate (0.030 ± 0.005). The reduction of fine dust load after the adjustment leads to a reduction of the SW cooling at the top of the atmosphere (TOA). To improve agreement against a semi-observationally based estimate of the radiative effect efficiency at TOA, we find that a less absorptive SW dust refractive index is required for coarser aspherical dust. Thus, only a minor difference is estimated for the net global dust radiative effect at TOA (−0.08 vs. −0.00 W m−2 on a global scale). Conversely, our sensitivity simulations reveal that the surface warming is substantially enhanced near the strong dust source regions (less cooling to −0.23 from −0.60 W m−2 on a global scale). Thus, less atmospheric radiative heating is estimated near the major source regions (less heating to 0.15 from 0.59 W m−2 on a global scale), because of enhanced LW warming at the surface by the synergy of coarser size and aspherical shape.

simulated dust properties↗

Application of Digital Image Correlation in Wind Tunnel

Digital image correlation (DIC) is a non-contact measurement technique that has been used in various applications in multiple industries, from microscopic specimens all the way to large scale structures. This project involved using DIC to capture wing deflection under simulated wind loading at various angles of attack (AoA). A subscale model of a fixed-wing aircraft, shown in Figure 1, was used in the 14-footby 22-footsubsonicwind tunnel at the NASA Langley Research Center. The setup used two pairs of cameras mounted on the ceiling of the tunnel to view the starboard and port side wings. Aluminum framing was used to rigidly mount the cameras to beams in the ceiling. Camera setup challenges due to the confined space included obtaining even lighting and working around infrared (IR) cameras that were used to capture the flow over the wing. Remote connection was used to access data acquisition computers from computers in the control room. Eight measurement locations on each wing were made of 1-inch-diametercircular silver dry transfer decals that did not alter the air flow across the wing. These circles were speckled with a black ink pen and were used for the IR camera as well as for DIC systems. A mock setup outside the wind tunnel was used to optimize the camera setup and verify that the speckled tape provided sufficient correlation. DIC was used to track the position of seven locations as the AoA of the subscale model changed from −10 degrees to +10 degrees in 1-degree increments. The model was rotated at a fixed height about the center of the fuselage from −7 degrees to +10 degrees. The height of the model had to be lowered to achieve AoA slower than −7degrees due to geometric constraints of the cart supporting the model and the wind tunnel. The source of light was stationary relative to the model, so the exposure time had to be adjusted for different wing regions and AoA values. The three-dimensional (3D) visualization of the markings and the two-dimensional (2D) projection of these points onto the port wing at 0-degree AoA is shown in Figure 2.

Matlock Mennu↗

Development of a Numerical Model for High-Temperature Shape Memory Alloys

A thermomechanical hysteresis model for a high-temperature shape memory alloy (HTSMA) actuator material is presented. The model is capable of predicting strain output of a tensile-loaded HTSMA when excited by arbitrary temperature-stress inputs for the purpose of actuator and controls design. Common quasi-static generalized Preisach hysteresis models available in the literature require large sets of experimental data for model identification at a particular operating point, and substantially more data for multiple operating points. The novel algorithm introduced here proposes an alternate approach to Preisach methods that is better suited for research-stage alloys, such as recently-developed HTSMAs, for which a complete database is not yet available. A detailed description of the minor loop hysteresis model is presented in this paper, as well as a methodology for determination of model parameters. The model is then qualitatively evaluated with respect to well-established Preisach properties and against a set of low-temperature cycled loading data using a modified form of the one-dimensional Brinson constitutive equation. The computationally efficient algorithm demonstrates adherence to Preisach properties and excellent agreement to the validation data set.

DeCastro, Jonathan A.↗

Model Deformation Measurements at NASA Langley Research Center

Only recently have large amounts of model deformation data been acquired in NASA wind tunnels. This acquisition of model deformation data was made possible by the development of an automated video photogrammetric system to measure the changes in wing twist and bending under aerodynamic load. The measurement technique is based upon a single view photogrammetric determination of two dimensional coordinates of wing targets with a fixed third dimensional coordinate, namely the spanwise location. A major consideration in the development of the measurement system was that use of the technique must not appreciably reduce wind tunnel productivity. The measurement technique has been used successfully for a number of tests at four large production wind tunnels at NASA and a dedicated system is nearing completion for a fifth facility. These facilities are the National Transonic Facility, the Transonic Dynamics Tunnel, and the Unitary Plan Wind Tunnel at NASA Langley, and the 12-FT Pressure Tunnel at NASA Ames. A dedicated system for the Langley 16-Foot Transonic Tunnel is scheduled to be used for the first time for a test in September. The advantages, limitations, and strategy of the technique as currently used in NASA wind tunnels are presented. Model deformation data are presented which illustrate the value of these measurements. Plans for further enhancements to the technique are presented.

Burner, A. W.↗