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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 307 records · Page 17
All sourcesNASA NTRSDOE OSTI
NASA NTRS1989

Interdependent figure-of-merit software development

This program was undertaken in order to understand the complex nature of interdependent performance in space missions. At the first step in a planned sequence of progress, a spread sheet program was developed to evaluate different fuel/oxidizer combinations for a specific Martian mission. This program is to be linked with output attained using sophisticated software produced by Gordon and McBride. The programming to date makes use of 11 independent parameters. Optimization is essential when faced with the incredible magnitude of costs, risks, and benefits involved with space exploration. A system of weights needs to be devised on which to measure the options. It was the goal to devise a Figure of Merit (FoM) on which different choices can be presented and made. The plan was to model typical missions to Mars, identify the parameters, and vary them until the best one is found. Initially, most of the focus was placed on propellant selection.

Ramohalli, K.↗
NASA NTRS2021

Real-Time Culture-Independent Microbial Profiling Onboard the International Space Station using Nanopore Sequencing

For the past two decades, microbial monitoring of the International Space Station (ISS) has relied on culture-dependent methods that require return to Earth for analysis. This has a number of limitations, with the most significant being bias towards the detection of culturable organisms and the inherent delay between sample collection and ground-based analysis. In recent years, portable and easy-to-use molecular-based tools, such as Oxford Nanopore Technologies’ MinION™ sequencer and miniPCR bio’s miniPCR™ thermal cycler, have been validated onboard the ISS. Here, we report on the development, validation, and implementation of a swab-to-sequencer method that provides a culture-independent solution to real-time microbial profiling onboard the ISS. Method development focused on analysis of swabs collected in a low-biomass environment with limited facility resources and stringent controls on allowed processes and reagents. ISS-optimized procedures included enzymatic DNA extraction from a swab tip, bead-based purifications, altered buffers, and the use of miniPCR and the MinION. Validation was conducted through extensive ground-based assessments comparing current standard culture-dependent and newly developed culture-independent methods. Similar microbial distributions were observed between the two methods; however, as expected, the culture-independent data revealed microbial profiles with greater diversity. Protocol optimization and verification was established during NASA Extreme Environment Mission Operations (NEEMO) analog missions 21 and 22, respectively. Unique microbial profiles obtained from analog testing validated the swab-to-sequencer method in an extreme environment. Finally, four independent swab-to-sequencer experiments were conducted onboard the ISS by two crewmembers. Microorganisms identified from ISS swabs were consistent with historical culture-based data, and primarily consisted of commonly observed human-associated microbes. This simplified method has been streamlined for high ease-of-use for a non-trained crew to complete in an extreme environment, thereby enabling environmental and human health diagnostics in real-time as future missions take us beyond low-Earth orbit.

microbiology↗
NASA NTRS1981

A Module Experimental Process System Development Unit (MEPSDU)

The development of a cost effective process sequence that has the potential for the production of flat plate photovoltaic modules which meet the price goal in 1986 of 70 cents or less per Watt peak is described. The major accomplishments include (1) an improved AR coating technique; (2) the use of sand blast back clean-up to reduce clean up costs and to allow much of the Al paste to serve as a back conductor; and (3) the development of wave soldering for use with solar cells. Cells were processed to evaluate different process steps, a cell and minimodule test plan was prepared and data were collected for preliminary Samics cost analysis.

Source record↗
NASA NTRS1986

Space power system scheduling using an expert system

A most pressing problem in space exploration is timely spacecraft power system sequence generation, which requires the scheduling of a set of loads given a set of resource constraints. This is particularly important after an anomaly or failure. This paper discusses the power scheduling problem and how the software program, Plan-It, can be used as a consultant for scheduling power system activities. Modeling of power activities, human interface, and two of the many strategies used by Plan-It are discussed. Preliminary results showing the development of a conflict-free sequence from an initial sequence with conflicts is presented. It shows that a 4-day schedule can be generated in a matter of a few minutes, which provides sufficient time in many cases to aid the crew in the replanning of loads and generation use following a failure or anomaly.

Bahrami, K. A.↗
NASA NTRS2003

Conservation of Endo16 expression in sea urchins despite evolutionary divergence in both cis and trans-acting components of transcriptional regulation

Evolutionary changes in transcriptional regulation undoubtedly play an important role in creating morphological diversity. However, there is little information about the evolutionary dynamics of cis-regulatory sequences. This study examines the functional consequence of evolutionary changes in the Endo16 promoter of sea urchins. The Endo16 gene encodes a large extracellular protein that is expressed in the endoderm and may play a role in cell adhesion. Its promoter has been characterized in exceptional detail in the purple sea urchin, Strongylocentrotus purpuratus. We have characterized the structure and function of the Endo16 promoter from a second sea urchin species, Lytechinus variegatus. The Endo16 promoter sequences have evolved in a strongly mosaic manner since these species diverged approximately 35 million years ago: the most proximal region (module A) is conserved, but the remaining modules (B-G) are unalignable. Despite extensive divergence in promoter sequences, the pattern of Endo16 transcription is largely conserved during embryonic and larval development. Transient expression assays demonstrate that 2.2 kb of upstream sequence in either species is sufficient to drive GFP reporter expression that correctly mimics this pattern of Endo16 transcription. Reciprocal cross-species transient expression assays imply that changes have also evolved in the set of transcription factors that interact with the Endo16 promoter. Taken together, these results suggest that stabilizing selection on the transcriptional output may have operated to maintain a similar pattern of Endo16 expression in S. purpuratus and L. variegatus, despite dramatic divergence in promoter sequence and mechanisms of transcriptional regulation.

NASA Discipline Evolutionary Biology↗
NASA NTRS2000

Multi-Agent Diagnosis and Control of an Air Revitalization System for Life Support in Space

An architecture of interoperating agents has been developed to provide control and fault management for advanced life support systems in space. In this adjustable autonomy architecture, software agents coordinate with human agents and provide support in novel fault management situations. This architecture combines the Livingstone model-based mode identification and reconfiguration (MIR) system with the 3T architecture for autonomous flexible command and control. The MIR software agent performs model-based state identification and diagnosis. MIR identifies novel recovery configurations and the set of commands required for the recovery. The AZT procedural executive and the human operator use the diagnoses and recovery recommendations, and provide command sequencing. User interface extensions have been developed to support human monitoring of both AZT and MIR data and activities. This architecture has been demonstrated performing control and fault management for an oxygen production system for air revitalization in space. The software operates in a dynamic simulation testbed.

Malin, Jane T.↗
NASA NTRS1984

Delineating mid- and low-level water vapor patterns in pre-convective environments using VAS moisture channels

Infrared and visible imagery from VAS are used to delineate mid- and lower-tropospheric moisture fields for a variety of severe storm cases in the southern and central United States. The ability of sequences of images to isolate areas of large negative vertical moisture gradients and apparent convective instability prior to the onset of convective storms is assessed. A variety of image combination procedures are used to deduce the stability fields which are then compared with the available radiosonde data. The results for several severe storm cases indicate that VAS can detect mid- and low-level mesoscale water vapor fields as distinct radiometric signals. The VAS imagery shows a strong tendency for thunderstorms to develop along the edges of bands of midlevel dryness as they overtake either preexisting or developing low-level moisture maxima. Image sequences depict the speed with which deep moist and dry layers can develop and move.

Petersen, R. A.↗
NASA NTRS2009

Aerocapture Guidance and Performance at Mars for High-Mass Systems

The Mars Entry, Descent, and Landing System Analysis (EDL-SA) project has been tasked with performing systems analysis to identify the optimal technologies required to land a 20-50 MT Exploration-class mission on Mars. It has been shown that it is not possible to safely land these large systems using heritage Mars EDL systems, or analogous Earth or Moon EDL systems. In 2007, NASA conducted a Mars Exploration Architecture Study which included an in depth review of the science motivations and engineering technology requirements for a human Mars mission campaign. This study resulted in an update to the Mars Design Reference Architecture (DRA 5.0). Among the primary findings and recommendations was the conclusion that landing of large payloads (greater than 1 MT) on the surface of Mars remains a key architectural challenge. Additionally, research and system studies of fundamental EDL technologies were highly recommended. The EDL-SA project identified the candidate technologies and assembled them into full capture and EDL sequences so that simulations could be developed to evaluate them. The chosen architectures combine the various technologies of interest in eight different ways. For aerocapture, only two scenarios were considered. The first is a rigid mid-L/D aeroshell (AS), which is represented in architectures 1, 4, 5, and 7. This scenario calls for a vehicle that flies at a 55-degree angle of attack, resulting in ballistic coefficient and L/D values of 490 kg/m 2 and 0.43, respectively. The second is a lifting hypersonic inflatable aerodynamic decelerator (HIAD), which is represented in architectures 2, 6, and 8. This scenario requires the vehicle to fly at a 22.2- degree angle of attack, which correlates to an L/D of 0.3 and was sized to provide a ballistic coefficient of 165 kg/m 2 . Architecture 3 is an all-propulsive sequence, and is not considered in this study.

Zumwalt, Carlie H.↗
NASA NTRS1991

Annular denuder systems: Precision and applicability to stratospheric sampling

Annular denuder systems (ADS) are designed to sample both gases and particles from ambient air without cross interference. The ADS's were used to detect chemical gradients over rural forest canopies. Accurate and precise methods for the sampling and analysis of low concentrations of gaseous and particulate species over short sampling periods were developed. Typical analytical precision data for nitrate and sulfate are shown. Both sampling and analytical precision data for a 2 hour test using four collocated ADS's are presented. On this particular day, the overall precision for HNO3 was unusually poor. The overall precision for the major constituents of interest is generally about 3 to 5 percent for typical ambient concentrations. The ADS's could potentially be used to determine the concentrations of HNO3 and fine-particle nitrate in the stratosphere, and to simultaneously characterize the chemical composition of stratospheric aerosols. Assuming 50 mb pressure, a 2 hour sampling time, a 50 Lpm sampling rate, and a low blank value, an overal precision of about 15 percent should be possible for 1 ppbv of HNO3 or nitrate, which would include nitric-acid trihydrate (NAT); and pump-driven systems could accommodate more complex systems involving denuders and filter packs in sequence. Alternate coatings could possibly be developed to selectively sample species such as Cl2 and ClNO3. The ADS's might also be useful in laboratory studies of heterogeneous chemical reactions involving NAT aerosols.

Randtke, Stephen J.↗
NASA NTRS1997

The Carbon-Rich Dust Sequence: Infrared Spectral Classification of Carbon Stars

We have developed a classification system for the infrared spectral emission from carbon stars, using a sample of 96 bright carbon-rich variables associated with the asymptotic giant branch. In addition to the stellar contribution, most spectra include the 11.2 micron emission feature from SiC and either a smooth cool continuum from amorphous carbon or a secondary emission feature at 9.0 microns. We have identified a carbon-rich dust sequence along which the amorphous carbon component grows while the 9.0 micron feature declines in strength. Along this spectral sequence, the fraction of Miras increases, as does the period of variability, the mass-loss rate, and the thickness of the circumstellar shell. Thus the carbon-rich dust sequence appears to be an evolutionary sequence. One class of spectra shows a particularly strong 9.0 micron feature, Enhanced C/O ratio, and several other unusual properties that suggest a different sequence, perhaps related to J stars.

Solan, G. C.↗
NASA NTRS1993

Phase holograms in PMMA with proximity effect correction

Complex computer generated phase holograms (CGPH's) have been fabricated in PMMA by partial e-beam exposure and subsequent partial development. The CGPH was encoded as a sequence of phase delay pixels and written by the JEOL JBX-5D2 E-beam lithography system, a different dose being assigned to each value of phase delay. Following carefully controlled partial development, the pattern appeared rendered in relief in the PMMA, which then acts as the phase-delay medium. The exposure dose was in the range 20-200 micro-C/sq cm, and very aggressive development in pure acetone led to low contrast. This enabled etch depth control to better than plus or minus lambda(sub vis)/60. That result was obtained by exposing isolated 50 micron square patches and measuring resist removal over the central area where the proximity effect dose was uniform and related only to the local exposure. For complex CGPH's with pixel size of the order of the e-beam proximity effect radius, the patterns must be corrected for the extra exposure caused by electrons scattered back up out of the substrate. This has been accomplished by deconvolving the two-dimensional dose deposition function with the desired dose pattern. The deposition function, which plays much the same role as an instrument response function, was carefully measured under the exact conditions used to expose the samples. The devices fabricated were designed with 16 equal phase steps per retardation cycle, were up to 1 cm square, and consisted of up to 100 million 0.3-2.0 micron square pixels. Data files were up to 500 MB long and exposure times ranged to tens of hours. A Fresnel phase lens was fabricated that had diffraction limited optical performance with better than 85 percent efficiency.

Maker, Paul D.↗
NASA NTRSDate not supplied

Deciphering Spaceflight Medical Risks Using High-Performance Computing and Next Generation Sequencing Data From Model Organisms

Somatic mutations are acquired point mutations and other forms of genetic alteration in the DNA of somatic cells in the body. Unlike germline mutations, which can be passed on from one individual to another, somatic mutations are not heritable. Somatic mutation (also called genetic sequence variation) has been recognized for decades as an important mechanism for initiating the development of cancer. Now, with the advent of next generation sequencing (NGS), the study of somatic mutation has become much more accessible, enabling genome scientists to characterize somatic mutations in a comprehensive fashion across the entire genome. From recent studies, it is now apparent that other disease processes besides cancer may be influenced by somatic mutation as well, including degenerative processes and inflammatory diseases. Cancer, degenerative diseases and inflammatory processes are all of concern in the setting of spaceflight. Study of somatic mutation analysis, therefore, is an important new tool for examining some of the earliest changes in the genome that lead to disease. This approach has tremendous potential for NASA, for analysis of both model organisms and humans.

Somatic mutation on ISS↗
NASA NTRS1980

Mechanisms of fatigue damage in boron/aluminum composites

Tensile fatigue tests were conducted on several laminates of boron/aluminum (6061-0). In laminates with 0 deg fibers on the outside, an analysis that identifies "shakedown" conditions predicted the stress amplitude below which no fatigue damage accumulated. A fatigue damage accumulation model which relates matrix fatigue cracking and the overall laminate properties is described. A model for the saturation damage stage development is presented, that identical laminates, tested in directions 90 deg apart (such that one layup has 90 deg outer plies and the other 0 deg), have different fatigue behaviors due to the stacking sequence. The 90 deg plies on the surface develop cracks earlier than predicted by shakedown. An attempt was made to explain this stacking sequence effect. Variable load history effects on the fatigue damage response were investigated. Tests reveal that for a given stress ratio the specimen seeks the saturation damage state for the largest stress range to which it is subjected. It was also found that little damage is generated by shifting a given stress range down, whereas significant damage may be created by shifting it upward. The laminate stresses were always tensile.

Johnson, W. S.↗
NASA NTRS1994

Attempt of automated space network operations at ETS-VI experimental data relay system

National Space Development Agency of Japan (NASDA) is to perform experimental operations to acquire necessary technology for the future inter-satellite communications configured with a data relay satellite. This paper intends to overview functions of the experimental ground system which NASDA has developed for the Engineering Test Satellite VI (ETS-VI) Data Relay and Tracking Experiment, and to introduce Space Network System Operations Procedure (SNSOP) method with an example of Ka-band Single Access (KSA) acquisition sequence. To reduce operational load, SNSOP is developed with the concept of automated control and monitor of both ground terminal and data relay satellite. To perform acquisition and tracking operations fluently, the information exchange with user spacecraft controllers is automated by SNSOP functions.

Ishihara, Kiyoomi↗
NASA NTRS1993

Mutations in the putative calcium-binding domain of polyomavirus VP1 affect capsid assembly

Calcium ions appear to play a major role in maintaining the structural integrity of the polyomavirus and are likely involved in the processes of viral uncoating and assembly. Previous studies demonstrated that a VP1 fragment extending from Pro-232 to Asp-364 has calcium-binding capabilities. This fragment contains an amino acid stretch from Asp-266 to Glu-277 which is quite similar in sequence to the amino acids that make up the calcium-binding EF hand structures found in many proteins. To assess the contribution of this domain to polyomavirus structural integrity, the effects of mutations in this region were examined by transfecting mutated viral DNA into susceptible cells. Immunofluorescence studies indicated that although viral protein synthesis occurred normally, infective viral progeny were not produced in cells transfected with polyomavirus genomes encoding either a VP1 molecule lacking amino acids Thr-262 through Gly-276 or a VP1 molecule containing a mutation of Asp-266 to Ala. VP1 molecules containing the deletion mutation were unable to bind 45Ca in an in vitro assay. Upon expression in Escherichia coli and purification by immunoaffinity chromatography, wild-type VP1 was isolated as pentameric, capsomere-like structures which could be induced to form capsid-like structures upon addition of CaCl2, consistent with previous studies. However, although VP1 containing the point mutation was isolated as pentamers which were indistinguishable from wild-type VP1 pentamers, addition of CaCl2 did not result in their assembly into capsid-like structures. Immunogold labeling and electron microscopy studies of transfected mammalian cells provided in vivo evidence that a mutation in this region affects the process of viral assembly.

Non-NASA Center↗
NASA NTRS1972

Pseudorandom noise for telemetry error rate measurement applications and limitations.

A pseudorandom noise (PRN) generator functional design has been developed which is superior to the commercially available instrument in usable bandwidth and in the closeness of fit to the gaussian probability distribution in the 'tails' of the curve. The principal disadvantage of PRN sources for bit error rate (BER) measurements is that the probability distribution is truncated in the tails. This truncation of the probability distribution results in a similar truncation of the BER curve - i.e., there is a minimum BER which can be measured, below which the only possible result is zero. The minimum nonzero BER actually computed with the PRN source developed was 0.00001 with a pseudorandom sequence of 131,071 bits. It is theoretically possible, with a longer sequence, to achieve a minimum BER of 0.000001 with the same design.

Hopkins, P. M.↗
NASA NTRS1973

The CADSS design automation system

This research was designed to implement and extend a previously defined design automation system for the design of small digital structures. A description is included of the higher level language developed to describe systems as a sequence of register transfer operations. The system simulator which is used to determine if the original description is correct is also discussed. The design automation system produces tables describing the state transistions of the system and the operation of all registers. In addition all Boolean equations specifying system operation are minimized and converted to NAND gate structures. Suggestions for further extensions to the system are also given.

Franke, E. A.↗
NASA NTRS1977

Measurements of Cumulonimbus Clouds using quantitative satellite and radar data

Results are reported for a preliminary study of SMS-2 digital brightness and IR data obtained at frequent 5-7.5 min intervals. The clouds studied were over the Central and Great Plains in midlatitudes and thus were typical of an environment much different from that of the tropical oceans. The satellite data are compared to radar data for both a severe weather event and weak thundershower activity of the type which might be a target for weather modification efforts. The relative importance of short time interval satellite data is shown for both cases, and possible relationships between the two types of data are presented. It is concluded that (1) using a threshold technique for visible reflected brightness, precipitating vs. nonprecipitating clouds can be discriminated; (2) brightness is well related to cloud size and shape; and (3) satellite-derived growth rates may be a significant parameter to be used in determining storm severity, especially if rapid time sequence data are used during the development phase of the storm.

Negri, A. J.↗