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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 325 records · Page 18
All sourcesNASA NTRSDOE OSTI
NASA NTRS2001

Accuracy for detection of simulated lesions: comparison of fluid-attenuated inversion-recovery, proton density--weighted, and T2-weighted synthetic brain MR imaging

OBJECTIVE: The objective of our study was to determine the effects of MR sequence (fluid-attenuated inversion-recovery [FLAIR], proton density--weighted, and T2-weighted) and of lesion location on sensitivity and specificity of lesion detection. MATERIALS AND METHODS: We generated FLAIR, proton density-weighted, and T2-weighted brain images with 3-mm lesions using published parameters for acute multiple sclerosis plaques. Each image contained from zero to five lesions that were distributed among cortical-subcortical, periventricular, and deep white matter regions; on either side; and anterior or posterior in position. We presented images of 540 lesions, distributed among 2592 image regions, to six neuroradiologists. We constructed a contingency table for image regions with lesions and another for image regions without lesions (normal). Each table included the following: the reviewer's number (1--6); the MR sequence; the side, position, and region of the lesion; and the reviewer's response (lesion present or absent [normal]). We performed chi-square and log-linear analyses. RESULTS: The FLAIR sequence yielded the highest true-positive rates (p < 0.001) and the highest true-negative rates (p < 0.001). Regions also differed in reviewers' true-positive rates (p < 0.001) and true-negative rates (p = 0.002). The true-positive rate model generated by log-linear analysis contained an additional sequence-location interaction. The true-negative rate model generated by log-linear analysis confirmed these associations, but no higher order interactions were added. CONCLUSION: We developed software with which we can generate brain images of a wide range of pulse sequences and that allows us to specify the location, size, shape, and intrinsic characteristics of simulated lesions. We found that the use of FLAIR sequences increases detection accuracy for cortical-subcortical and periventricular lesions over that associated with proton density- and T2-weighted sequences.

NASA Discipline Neuroscience↗
NASA NTRS1984

Cell wall pH and auxin transport velocity

According to the chemiosmotic polar diffusion hypothesis, auxin pulse velocity and basal secretion should increase with decreasing cell wall pH. Experiments were designed to test this prediction. Avena coleoptile sections were preincubated in either fusicoccin (FC), cycloheximide, pH 4.0, or pH 8.0 buffer and subsequently their polar transport capacities were determined. Relative to controls, FC enhanced auxin (IAA) uptake while CHI and pH 8.0 buffer reduced IAA uptake. Nevertheless, FC reduced IAA pulse velocity while cycloheximide increased velocity. Additional experiments showed that delivery of auxin to receivers is enhanced by increased receiver pH. This phenomenon was overcome by a pretreatment of the tissue with IAA. Our data suggest that while acidic wall pH values facilitate cellular IAA uptake, they do not enhance pulse velocity or basal secretion. These findings are inconsistent with the chemiosmotic hypothesis for auxin transport.

Plant Growth Regulators/metabolism↗
NASA NTRS2000

Anatomic patterning in the expression of vestibulosympathetic reflexes

To investigate the possibility that expression of vestibulosympathetic reflexes (VSR) is related to a nerve's anatomic location rather than its target organ, we compared VSR recorded from the same type of postganglionic fiber [muscle vasoconstrictor (MVC)] located at three different rostrocaudal levels: hindlimb, forelimb, and face. Experiments were performed on chloralose-anesthetized cats, and vestibular afferents were stimulated electrically. Single MVC unit activity was extracted by spike shape analysis of few-fiber recordings, and unit discrimination was confirmed by autocorrelation. Poststimulus time histogram analysis revealed that about half of the neurons were initially inhibited by vestibular stimulation (type 1 response), whereas the other MVC fibers were initially strongly excited (type 2 response). MVC units with types 1 and 2 responses were present in the same nerve fascicle. Barosensitivity was equivalent in the two groups, but fibers showing type 1 responses fired significantly faster than those giving type 2 responses (0.29 +/- 0.04 vs. 0.20 +/- 0.02 Hz). Nerve fibers with type 1 responses were most common in the hindlimb (21 of 29 units) and least common in the face (2 of 11 units), the difference in relative proportion being significant (P < 0.05, chi(2) test). These results support the hypothesis that VSR are anatomically patterned.

Non-NASA Center↗
NASA NTRS2004

A Geomagnetic Estimate of Mean Paleointensity

To test a statistical hypothesis about Earth's magnetic field against paleomagnetism, the present field is used to estimate time averaged paleointensity. The estimate uses the modem magnetic multipole spectrum R(n), which gives the mean square induction represented by spherical harmonics of degree n averaged over the sphere of radius a = 6371.2 km. The hypothesis asserts that the low degree multipole powers of the core-source field are distributed as chi-squared with 2n+l degrees of freedom and expectation values {R(n)} = K[(n+l/2)/n(n+l](c/a)(sup 2n+4), where c is the 3480 km radius of Earth's core. (This is compatible with a usually mainly geocentric axial dipolar field). Amplitude K is estimated by fitting theoretical to observational spectra through degree 12. The resulting calibrated expectation spectrum is summed through degree 12 to estimate expected square intensity {F(sup 2)}. The sum also estimates {F(sup 2)} averaged over geologic time, in so far as the present magnetic spectrum is a fair sample of that generated in the past by core geodynamic processes.

Voorhies, Coerte↗
NASA NTRS1998

Anion channels and the stimulation of anthocyanin accumulation by blue light in Arabidopsis seedlings

Activation of anion channels by blue light begins within seconds of irradiation in seedlings and is related to the ensuing growth inhibition. 5-Nitro-2-(3-phenylpropylamino)-benzoic acid (NPPB) is a potent, selective, and reversible blocker of these anion channels in Arabidopsis thaliana. Here we show that 20 microM NPPB blocked 72% of the blue-light-induced accumulation of anthocyanin pigments in seedlings. Feeding biosynthetic intermediates to wild-type and tt5 seedlings provided evidence that NPPB prevented blue light from up-regulating one or more steps between and including phenylalanine ammonia lyase and chalcone isomerase. NPPB was found to have no significant effect on the blue-light-induced increase in transcript levels of PAL1, CHS, CHI, or DFR, which are genes that encode anthocyanin-biosynthetic enzymes. Immunoblots revealed that NPPB also did not inhibit the accumulation of the chalcone synthase, chalcone isomerase, or flavanone-3-hydroxylase proteins. This is in contrast to the reduced anthocyanin accumulation displayed by a mutant lacking the HY4 blue-light receptor, as hy4 displayed reduced expression of the above enzymes. Taken together, the data indicate that blue light acting through HY4 leads to an increase in the amount of biosynthetic enzymes but blue light must also act through a separate, anion-channel-dependent system to create a fully functional biosynthetic pathway.

Non-NASA Center↗
NASA NTRS1997

Modeling the effects of exercise during 100% oxygen prebreathe on the risk of hypobaric decompression sickness

BACKGROUND: Several previous studies indicated that exercise during prebreathe with 100% O2 decreased the incidence of hypobaric decompression sickness (DCS). We report a meta-analysis of these investigations combined with a new study in our laboratory to develop a statistical model as a predictive tool for DCS. HYPOTHESIS: Exercise during prebreathe increases N2 elimination in a theoretical 360-min half-time compartment decreasing the incidence of DCS. METHODS: A dose-response probability tissue ratio (TR) model with 95% confidence limits was created for two groups, prebreathe with exercise (n = 113) and resting prebreathe (n = 113), using nonlinear regression analysis with maximum likelihood optimization. RESULTS: The model predicted that prebreathe exercise would reduce the residual N2 in a 360-min half-time compartment to a level analogous to that in a 180-min compartment. This finding supported the hypothesis. The incidence of DCS for the exercise prebreathe group was significantly decreased (Chi-Square = 17.1, p < 0.0001) from the resting prebreathe group. CONCLUSIONS: The results suggested that exercise during prebreathe increases tissue perfusion and N2 elimination approximately 2-fold and markedly lowers the risk of DCS. Based on the model, the prebreathe duration may be reduced from 240 min to a predicted 91 min for the protocol in our study, but this remains to be verified. The model provides a useful planning tool to develop and test appropriate prebreathe exercise protocols and to predict DCS risks for astronauts.

NASA Program Environmental Health↗
NASA NTRS1996

Cerebral cortical neurons with activity linked to central neurogenic spontaneous and evoked elevations in cerebral blood flow

We recorded neurons in rat cerebral cortex with activity relating to the neurogenic elevations in regional cerebral blood flow (rCBF) coupled to stereotyped bursts of EEG activity, burst-cerebrovascular wave complexes, appearing spontaneously or evoked by electrical stimulation of rostral ventrolateral medulla (RVL) or fastigial nucleus (FN). Of 333 spontaneously active neurons only 15 (5%), in layers 5-6, consistently (P < 0.05, chi-square) increased their activity during the earliest potential of the complex, approximately 1.3 s before the rise of rCBF, and during the minutes-long elevation of rCBF elicited by 10 s of stimulation of RVL or FN. The results indicate the presence of a small population of neurons in deep cortical laminae whose activity correlates with neurogenic elevations of rCBF. These neurons may function to transduce afferent neuronal signals into vasodilation.

NASA Discipline Cardiopulmonary↗
NASA NTRS1943

Experimental Investigation of a Model of a Two-Stage Turboblower

In the present paper an investigation is made of two stages of a multistage turboblower having a vaneless diffuser behind the impeller and guide vanes at the inlet to the nest stage. The method employed was that of investigating the performance of the successive elements of the blower (the impeller, vaneless diffuser, ets.) whereby the kinematics of the flow through the blower could be followed and the pressure at the different points computed. The character of the flow and the physical significance of the loss coefficients could thereby be determined so as to secure the best agreement of the computed with the actual performance of the blower. Since the tests were carried out for various delivery volumes, the dependence of the coefficients on a number of factors (angle of attack, velocities, etc.) could be obtained. The distribution of the losses that occur during the transformation of dynamic pressure at the impeller exit into static pressure could be found and likewise the range within which the friction coefficient varies in the vaneless diffuser. With the aid of factors having a certain physical significance, the centrifugal blower could be computed on the basis of a more or less schematical consideration of the phenomena occuring during the air flow through it, and the use of arbitrary factors and recourse to the geometrical similtude law thus avoided. The present investigation largely summarizes all the previous work af the CHI Blower Section on the different elements of a centrifugal blower. Some considerations on the analysis of model test data for application to full-scale are presented in the appendix.

Dovjik, s.↗
NASA NTRS2004

A Preliminary ZEUS Lightning Location Error Analysis Using a Modified Retrieval Theory

The ZEUS long-range VLF arrival time difference lightning detection network now covers both Europe and Africa, and there are plans for further expansion into the western hemisphere. In order to fully optimize and assess ZEUS lightning location retrieval errors and to determine the best placement of future receivers expected to be added to the network, a software package is being developed jointly between the NASA Marshall Space Flight Center (MSFC) and the University of Nevada Las Vegas (UNLV). The software package, called the ZEUS Error Analysis for Lightning (ZEAL), will be used to obtain global scale lightning location retrieval error maps using both a Monte Carlo approach and chi-squared curvature matrix theory. At the core of ZEAL will be an implementation of an Iterative Oblate (IO) lightning location retrieval method recently developed at MSFC. The IO method will be appropriately modified to account for variable wave propagation speed, and the new retrieval results will be compared with the current ZEUS retrieval algorithm to assess potential improvements. In this preliminary ZEAL work effort, we defined 5000 source locations evenly distributed across the Earth. We then used the existing (as well as potential future ZEUS sites) to simulate arrival time data between source and ZEUS site. A total of 100 sources were considered at each of the 5000 locations, and timing errors were selected from a normal distribution having a mean of 0 seconds and a standard deviation of 20 microseconds. This simulated "noisy" dataset was analyzed using the IO algorithm to estimate source locations. The exact locations were compared with the retrieved locations, and the results are summarized via several color-coded "error maps."

Elander, Valjean↗
NASA NTRS2004

Dimensional Reduction: A Method for Retrieving Lightning Charge

A method is introduced for retrieving the locations and magnitudes of charges deposited by a lightning flash using multiple ground-based electric field change measurements. The method, called Dimensional Reduction, reduces the number of unknowns in a discrete 2-charge model from the standard of eight (x, y, z, Q, x' , y' , z' , Q') to just four (x, y, z, Q). This reduction is accomplished by analyzing "residual measurements" that are formed by subtracting from each ground-based electric field change the contribution due to the source (x, y, z, Q). Using an improved analytic solution to the four-parameter point charge model (or "Q-model") the residual measurements are inverted to find the associated "residual source." For flash charge depositions that look approximately like two arbitrary charges, the residual source will be modeled accurately when (x, y, z, Q) is accurate. Hence, one need only minimize a chi-squared goodness-of-fit that is a function of the four variables (x, y, z, Q), rather than one that is a function of the eight variables (x, y, z, Q, x , y , z , Q ). The accuracy of the method is assessed by inverting computer-simulated electric field changes produced from known charge sources. The method is also applied to analyze real lightning electric field change data derived from the NASA Kennedy Space Center (KSC) and United States Air Force (USAF) Eastern Range (ER) ground-based field mill network It is shown that the charge retrievals compare favorably with associated ancillary ground- and satellite- based lightning measurements.

Koshak, William↗
NASA NTRS2004

A Geomagnetic Estimate of Mean Paleointensity

To test a statistical hypothesis about Earth's magnetic field against paleomagnetism, the present field is used to estimate time averaged paleointensity. The estimate used the modern magnetic multipole spectrum R(n), which gives the mean square induction represented by spherical harmonics of degree n averaged over the sphere of radius a = 6371.2 km. The hypothesis asserts that low degree multi-pole powers of the coresource field are distributed as chi-squared with 2n+1 degrees of freedom and expectation values, where c is the 3480 km radius of the Earth's core. (This is compatible with a usually mainly geocentric axial dipolar field). Amplitude K is estimated by fitting theoretical to observational spectra through degree 12. The resulting calibrated expectation spectrum is summed through degree 12 to estimate expected square intensity F(exp 2). The sum also estimates F(exp 2) averaged over geologic time, in so far as the present magnetic spectrum is a fair sample of that generated in the past by core geodynamic processes. Additional information is included in the original extended abstract.

Voorhies, Coerte V.↗
NASA NTRS2005

Revised Thorium Abundances for Lunar Red Spots

Lunar red spots are features on the nearside of the Moon that are characterized by high albedo and by a strong absorption in the ultraviolet. These red spots include the Gruithuisen domes, the Mairan domes, Hansteen Alpha, the southern portion of Montes Riphaeus, Darney Chi and Tau, Helmet, and an area near the Lassell crater. It has been suggested that many of the red spots are extrusive, nonmare, volcanic features that could be composed of an evolved lithlogy enriched in thorium. In fact, Hawke et al. used morphological characteristics to show that Hansteen Alpha is a nonmare volcanic construct. However, because the apparent Th abundances (6 - 7 ppm) were lower than that expected for evolved rock types, Hawke et al. concluded that Hansteen Alpha was composed of an unknown rock type. Subsequent studies by Lawrence et al. used improved knowledge of the Th spatial distribution for small area features on the lunar surface to revisit the interpretation of Th abundances at the Hansteen Alpha red spot. As part of their study, Lawrence et al. used a forward modeling technique to show that the Th abundance at Hansteen Alpha is not 6 ppm, but is more likely closer to 25 ppm, a value consistent with evolved lithologies. This positive correlation between the morphology and composition of Hansteen Alpha provides support for the presence of evolved lithologies on the lunar surface. It is possible, however, that Hansteen Alpha represents an isolated occurrence of non-mare volcanism. That is why we have chosen to use the forward modeling technique of Lawrence et al. to investigate the Th abundances at other lunar red spots, starting with the Gruithuisen domes. Additional information is included in the original extended abstract.

Hagerty, J. J.↗
NASA NTRS2005

How Does Abundance Affect the Strength of UV Emission in Elliptical Galaxies?

This program used the Far Ultraviolet Spectroscopic Explorer (FUSE) to observe elliptical galaxies with the intention of measuring the chemical abundances in their hot stellar populations. It was designed to complement an earlier FUSE program that observed elliptical galaxies with strong UV emission. The current program originally planned observations of two ellipticals with weak UV emission (M32 and M49). Once FUSE encountered pointing control problems in certain regions of the sky (particularly Virgo, which is very unfortunate for the study of ellipticals in general), M49 was replaced with the bulge of M31, which has a similar UV-to-optical flux ratio as the center of M49. As the closest elliptical galaxy and the one with the weakest UV-to-optical flux ratio, M32 was an obvious choice of target, but M49 was the ideal complementary target, because it has a very low reddening (unlike M32). With the inability of FUSE to point at Virgo, nearly all of the best elliptical galaxies (bright galaxies with low foreground extinction) were also lost, and this severely hampered three FUSE programs of the PI, all focused on the hot stellar populations of ellipticals. M31 was the best replacement for M49, but like M32, it suffers from significant foreground reddening. Strong Galactic ISM lines heavily contaminate the FUSE spectra of M31 and M32. These ISM lines are coincident with the photospheric lines from the stellar populations (whereas M49, with little foreground ISM and significant redshift, would not have suffered from this problem). We have reduced the faint (and thus difficult) data for M31 and M32, producing final co-added spectra representing all of the exposures, but we have not yet finished our analysis, due to the complication of the contaminating ISM. The silver lining here is the set of CHI lines at 1175 Angstroms, which are not significantly contaminated by the ISM. A comparison of the M31 spectrum with other galaxies observed by FEE showed a surprising result: the hot stars in M31 seem to have a similar carbon abundance to those stars in galaxies with much brighter UV emission. The fraction of these hot stars in a population should be a strong function of chemical abundances, so this finding warrants further exploration, and we are proceeding with our analysis. Because the UV emission in these galaxies comes from a population of extreme horizontal branch stars, the PI (Brown) presented this result at a June 2003 conference on such stars.

Sonneborn, George↗
NASA NTRS2000

Progress in the development of the MISTE flight experiment

The MISTE flight experiment plans to measure the specific heat at constant volume, C(sub v), and isothermal susceptibility chi(sup tau), near the (sup 3)He liquid-gas critical point. A new method for precisely determining the critical temperature is being evaluated and will be presented.

critical phenomena liquid-gas critical point↗
NASA NTRS2000

Test of phi(sup 2) model predictions near the (sup 3)He liquid-gas critical point

NASA is supporting the development of an experiment called MISTE (Microgravity Scaling Theory Experiment) for future International Space Station mission. The main objective of this flight experiment is to perform in-situ PVT, heat capacity at constant volume, C(sub v) and chi(sub tau), measurements in the asymptotic region near the (sup 3)He liquid-gas critical point.

critical phenomena liquid-gas critical point↗
NASA NTRS1995

Combinations of Earth Orientation Observations: SPACE94, COMB94, and POLE94

A Kalman filter has been used to combine all publicly available, independently determined measurements of the Earth's orientation taken by the modern, space-geodetic techniques of very long baseline interferometry, satellite laser ranging, lunar laser ranging, and the global positioning system. Prior to combining the data, tidal terms were removed from the UT1 measurements, outlying data points were deleted, series-specific corrections were applied for bias and rate, and the stated uncertainties of the measurements were adjusted by multiplying them by series-specific scale factors. Values for these bias- rate corrections and uncertainty scale factors were determined by an iterative, round-robin procedure wherein each data set is compared, in turn, to a combination of all other data sets. When applied to the measurements, the bias-rate corrections thus determined make the data sets agree with each other in bias and rate, and the uncertainty scale factors thus determined make the residual of each series (when differenced with a combination of all others) have a reduced chi-square of one. The corrected and adjusted series are then placed within an IERS reference frame by aligning them with the IERS Earth orientation series EOP (IERS)90C04. The result of combining these corrected, adjusted and aligned series is designated SPCE94 and spans October 6.0, 1976 to January 27.0, 1995 at daily intervals.

SPACE94 COMB94↗
NASA NTRS2007

Lightning Charge Retrievals: Dimensional Reduction, LDAR Constraints, and a First Comparison with LIS Satellite Data

A "dimensional reduction" (DR) method is introduced for analyzing lightning field changes (DELTAEs) whereby the number of unknowns in a discrete two-charge model is reduced from the standard eight (x, y, z, Q, x', y', z', Q') to just four (x, y, z, Q). The four unknowns (x, y, z, Q) are found by performing a numerical minimization of a chi-square function. At each step of the minimization, an Overdetermined Fixed Matrix (OFM) method is used to immediately retrieve the best "residual source" (x', y', z', Q'), given the values of (x, y, z, Q). In this way, all 8 parameters (x, y, z, Q, x', y', z', Q') are found, yet a numerical search of only 4 parameters (x, y, z, Q) is required. The DR method has been used to analyze lightning-caused DeltaEs derived from multiple ground-based electric field measurements at the NASA Kennedy Space Center (KSC) and USAF Eastern Range (ER). The accuracy of the DR method has been assessed by comparing retrievals with data provided by the Lightning Detection And Ranging (LDAR) system at the KSC-ER, and from least squares error estimation theory, and the method is shown to be a useful "stand-alone" charge retrieval tool. Since more than one charge distribution describes a finite set of DELTAEs (i.e., solutions are non-unique), and since there can exist appreciable differences in the physical characteristics of these solutions, not all DR solutions are physically acceptable. Hence, an alternative and more accurate method of analysis is introduced that uses LDAR data to constrain the geometry of the charge solutions, thereby removing physically unacceptable retrievals. The charge solutions derived from this method are shown to compare well with independent satellite- and ground-based observations of lightning in several Florida storms.

Koshak, W. J.↗