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At least 343 records · Page 19

Investigating Biological Responses to Space-like Radiation using the yeast Saccharomyces cerevisiae

As we plan crewed missions to the Moon, Mars, and beyond, it is essential to understand how persistent exposure to space radiation affects biology. Unlike on the International Space Station, where crew support and sample return are possible, experiments for long-duration missions require autonomous systems with no sample return. Human cells would be ideal biosensors, but limitations in culture methods, extended prelaunch storage, and long flight durations make it very difficult to keep human cells alive. Unlike other model systems, yeast can survive the constraints of long-duration spaceflight. Despite a billion years of evolution separating yeast from humans, we share homology in hundreds of genes important for basic cell function, including responses to DNA damage. Thus, yeast are excellent biosensors for detecting types/extent of damage induced by space radiation. BioSentinel is NASA’s latest biological CubeSat, and first interplanetary space bioscience mission. BioSentinel is manifested on Artemis 1, the first test flight of NASA’s Space Launch System, in the coming year. The BioSensor payload within BioSentinel contains two yeast strains. The wild type serves as a control for health and “normal” DNA damage repair (DDR). The rad51 deletion mutant is defective for DDR and will undergo alterations to growth and metabolism as it accumulates radiation damage. Changes in growth and metabolic activity will be measured using a 3-color LED detection system and the metabolic redox dye alamarBlue®. Preliminary tests indicate a significant change in alamarBlue response to space-like, low-dose ionizing radiation. We will discuss these findings in four parts – Introduction to biological CubeSats and the BioSentinel mission (presented by Sergio Santa Maria), preliminary responses to space-like ionizing radiation (presented here), a deeper dive into tracking metabolic changes after exposure to ionizing radiation (presented by Diana Gentry), and a look into methods for correcting flight optical data (presented by Abbey Kim). This work is funded by NASA’s Advanced Exploration Systems.

CubeSat↗

Investigating Molecular Responses to Space Radiation for Biological Missions Beyond Low Earth Orbit

As we plan crewed missions to the Moon, Mars, and beyond, it is essential to understand how persistent exposure to deep space radiation affects biology. Unlike on the International Space Station (ISS), where crew support and sample return are possible, experiments for long-duration missions require autonomous systems with no sample return. Human cells would be ideal biosensors, but limitations in culture methods, extended prelaunch storage, and long flight durations make it difficult to keep human cells alive. Unlike other model systems, yeast can survive the constraints of long-duration spaceflight. Despite a billion years of evolution separating yeast from humans, we share homology in hundreds of genes important for basic cell function, including responses to DNA damage. Thus, yeast are excellent biosensors for detecting types/extent of damage induced by space radiation. BioSentinel is NASA’s latest biological CubeSat, and first interplanetary space bioscience mission. BioSentinel is launching on Artemis 1, the first flight of NASA’s Space Launch System, in 2022. The BioSensor payload within BioSentinel contains two yeast strains. The wild type serves as a control for health and normal DNA damage repair (DDR). The rad51 deletion mutant is defective for DDR and will undergo alterations to growth and metabolism as it accumulates radiation damage. Changes in growth and metabolic activity will be measured using a 3-color LED detection system and the metabolic redox dye alamarBlue®. Preliminary tests indicate a significant change in alamarBlue responses to space-like, low-dose ionizing radiation. We will discuss these findings in five parts – Introduction to NASA’s biological CubeSats and BioSentinel (presented by Sergio Santa Maria), analysis of flight data from the ISS mission (presented by Kylie Akiyama), preliminary molecular responses to space radiation (presented here), a deeper dive into those pathways (presented by Kyra Keenan), and characterizing stress response through redox potential data (presented by Diana Gentry).

Lauren Courtney Liddell↗

Relativistic electrons in space.

This paper reviews the current state of knowledge concerning relativistic electrons, above 0.3 MeV, in interplanetary space, as measured by detectors on board satellites operating beyond the influence of the magnetosphere. The electrons have a galactic component, which at the lower energies is subject both to solar modulation and to spasmodic 'quiet time' increases and a direct solar component correlated with flare activity. The recent measurements have established the form of the differential energy spectrum of solar flare electrons. Electrons have been detected from flares behind the visible solar disk. Relativistic electrons do not appear to leave the sun at the time of the flash phase of the flare, although there are several signatures of electron acceleration at this time. The delay is interpreted as taking place during the transport of the electrons through the lower corona.

Simnett, G. M.↗

Understanding Space Weather Part III: the Sun's Domain

The Sun exports a continuous outflow of plasma into interplanetary space: the solar wind. The solar wind primarily comprises two components: high- and slow-speed flows. These move with velocities ranging from 200 to 800 km/s depending on the source of the particular flow. As well as its speed, the density, temperature, and even the composition of the solar wind change. Adding to its intrinsic variability, there are embedded transients resulting from flares and coronal mass ejections that further complicate its dynamics and space weather impacts. The solar wind interacts differently with each of the solar system objects it encounters based on their magnetic and atmospheric properties. Even more complex processes occur as the solar wind encounters the interstellar medium, at the outer boundaries of the Sun's domain. The solar wind stretches to beyond 100 au (where 1 au defined to be equal to 149 597 870 700 m) from the Sun, which means that Earth is essentially immersed in the very hot solar atmosphere, and that leads to many space weather impacts on life and society. The specific space weather impacts on Earth will be discussed in detail in the next two papers in this series.

Strong, Keith↗

Scheduling NASA's Deep Space Network: Priorities, Preferences, and Optimization

NASA's Deep Space Network (DSN) is the primary resource for communications and navigation for interplanetary space missions, for both NASA and partner agencies. Growth in mission demand, both in number of spacecraft and in data return, has led to increased loading levels on the network, and actual demand frequently exceeds network capacity. The DSN scheduling process involves peer-to-peer collaborative negotiation, which consumes significant time and resources in order to reach a baseline version of the schedule, and then to manage and agree to changes. Process delays are exacerbated by the high level of oversubscription experienced by the DSN: it is not unusual for the scheduling process to start with 20-40\% more requested time can be accommodated on the available antennas. The other NASA networks make use of a static mission priority list to address a similar problem: missions are ranked in priority order, then the schedule is populated by priority from highest to lowest. Such a mechanism would not work for DSN due to the heterogeneity of the mission set, and to the time-varying mission requirements with mission phase. This paper describes an alternative approach for the DSN that addresses key problems inherent in the current process --- oversubsubscription and how to "fairly'" reduce it to a manageable level. The main characteristics of the new approach are the use of loading-based limits based on balancing requested time, along with priorities and user preferences as the basis for optimization criteria that can be used by new algorithms.

Johnston, Mark D↗

User Preference Optimization for Oversubscribed Scheduling of NASA’s Deep Space Network

NASA’s Deep Space Network (DSN) is the primary resource for communications and navigation for interplanetary space missions, for both NASA and partner agencies. Growth in mission demand, both in number of spacecraft and in data return, has led to increased loading levels on the network, and actual demand frequently exceeds network capacity. The DSN scheduling process involves peer-to-peer collaborative negotiation, which consumes significant time and resources in order to reach a baseline version of the schedule, and then to manage and agree to changes. Process delays are exacerbated by the high level of oversubscription experienced by the DSN: it is not unusual for the scheduling process to start with 20-40% more requested time can be accommodated on the available antennas. The other NASA networks make use of a static mission priority list to address a similar problem: missions are ranked in priority order, then the schedule is populated by priority from highest to lowest. Such a mechanism would not work for DSN due to the heterogeneity of the mission set, and to the time-varying mission requirements with mission phase. This paper describes an alternative approach for the DSN that addresses key problems inherent in the current process — oversubsubscription and how to “fairly” reduce it to a manageable level. The main characteristics of the new approach are the use of loading-based limits based on balancing requested time, along with priorities and user preferences as the basis for optimization criteria that can be used by new algorithms.

Johnston, Mark D↗

A Demand Access Paradigm for NASA’s Deep Space Network

NASA’s Deep Space Network (DSN) is the primary resource for communications and navigation for interplanetary space missions, for both NASA and partner agencies. As part of an investigation into improved efficiency and responsiveness, we have been exploring and prototyping the infusion of a ”demand access” model into the DSN scheduling process. Today, DSN is fully pre-scheduled in advance, and many users rely on a stable schedule to plan their own spacecraft activities, weeks in advance of execution. However, a new class of missions is emerging that may not be scheduled as far in advance, and may be event-driven in coming across science targets at unpredictable times. These users could take advantage of an on-demand mechanism to download data. Simulations have shown that such a mechanism could improve latency (time from data collection to download) by 2x, as well as more efficiently utilize the available DSN antennas. In this paper, we describe a prototype of a demand access process and how it addresses the challenges of co-existing with a staticallyscheduled body of missions, while providing the benefits of lower latency science data return.

Lucena, Girly↗

Properties of Minor Ions in the Solar Wind and Implications for the Background Solar Wind Plasma

The scope of the investigation is to extract information on the properties of the bulk solar wind from the minor ion observations that are provided by instruments on board NASA space craft and theoretical model studies. Ion charge states measured in situ in interplanetary space are formed in the inner coronal regions below 5 solar radii, hence they carry information on the properties of the solar wind plasma in that region. The plasma parameters that are important in the ion forming processes are the electron density, the electron temperature and the flow speeds of the individual ion species. In addition, if the electron distribution function deviates from a Maxwellian already in the inner corona, then the enhanced tail of that distribution function, also called halo, greatly effects the ion composition. This study is carried out using solar wind models, coronal observations, and ion calculations in conjunction with the in situ observations.

Wagner, William↗

Heliospheric Physics and NASA's Vision for Space Exploration

The Vision for Space Exploration outlines NASA's development of a new generation of human-rated launch vehicles to replace the Space Shuttle and an architecture for exploring the Moon and Mars. The system--developed by the Constellation Program--includes a near term (approx. 2014) capability to provide crew and cargo service to the International Space Station after the Shuttle is retired in 2010 and a human return to the Moon no later than 2020. Constellation vehicles and systems will necessarily be required to operate efficiently, safely, and reliably in the space plasma and radiation environments of low Earth orbit, the Earth's magnetosphere, interplanetary space, and on the lunar surface. This presentation will provide an overview of the characteristics of space radiation and plasma environments relevant to lunar programs including the trans-lunar injection and trans-Earth injection trajectories through the Earth's radiation belts, solar wind surface dose and plasma wake charging environments in near lunar space, energetic solar particle events, and galactic cosmic rays and discusses the design and operational environments being developed for lunar program requirements to assure that systems operate successfully in the space environment.

Minow, Joseph I.↗

The Sun and Earth

Thus the Sun forms the basis for life on Earth via the black body radiation it emits. The Sun also emits mass in the form of the solar wind and the coronal mass ejections (CMEs). Mass emission also occurs in the form of solar energetic particles (SEPs), which happens during CMEs and solar flares. Both the mass and electromagnetic energy output of the Sun vary over a wide range of time scales, thus introducing disturbances on the space environment that extends from the Sun through the entire heliosphere including the magnetospheres and ionospheres of planets and moons of the solar system. Although our habitat is located in the neutral atmosphere of Earth, we are intimately connected to the non-neutral space environment starting from the ionosphere to the magnetosphere and to the vast interplanetary space. The variability of the solar mass emissions results in the interaction between the solar wind plasma and the magnetospheric plasma leading to huge disturbances in the geospace. The Sun ionizes our atmosphere and creates the ionosphere. The ionosphere can be severely disturbed by the transient energy input from solar flares and the solar wind during geomagnetic storms. The complex interplay between Earth's magnetic field and the solar magnetic field carried by the solar wind presents varying conditions that are both beneficial and hazardous to life on earth. This seminar presents some of the key aspects of this Sun-Earth connection that we have learned since the birth of space science as a scientific discipline some half a century ago.

Gopalswamy, Natchimuthuk↗

Space Pioneers and where they are now

A description of the Pioneer project, its history and achievements is given. Major discoveries concerning near and interplanetary space, the planets, and various comets are outlined. Anticipated future observations are considered. A list of Pioneer project launches, 1986 statuses, and project firsts is given.

Montoya, Earl J.↗

Interplanetary and near-Jupiter meteoroid environments - Preliminary results from the meteoroid detection experiment

Data on interplanetary and near-Jupiter micrometer-sized particle encounters from the meteoroid-detection experiment on Pioneer 10 indicate that Jupiter is much 'dustier' than interplanetary space. Whereas the near-earth particulate flux showed very little increase over the interplanetary flux, the near-Jupiter penetration flux was over two orders of magnitude higher than the interplanetary flux.

Kinard, W. H.↗

Shielded Heavy-Ion Environment Linear Detector (SHIELD): an experiment for the Radiation and Technology Demonstration (RTD) Mission

Radiological assessment of the many cosmic ion species of widely distributed energies requires the use of theoretical transport models to accurately describe diverse physical processes related to nuclear reactions in spacecraft structures, planetary atmospheres and surfaces, and tissues. Heavy-ion transport models that were designed to characterize shielded radiation fields have been validated through comparison with data from thick-target irradiation experiments at particle accelerators. With the RTD Mission comes a unique opportunity to validate existing radiation transport models and guide the development of tools for shield design. For the first time, transport properties will be measured in free-space to characterize the shielding effectiveness of materials that are likely to be aboard interplanetary space missions. Target materials composed of aluminum, advanced composite spacecraft structure and other shielding materials, helium (a propellant) and tissue equivalent matrices will be evaluated. Large solid state detectors will provide kinetic energy and charge identification for incident heavy-ions and for secondary ions created in the target material. Transport calculations using the HZETRN model suggest that 8 g cm -2 thick targets would be adequate to evaluate the shielding effectiveness during solar minimum activity conditions for a period of 30 days or more.

NASA Center LaRC↗

Plasma Environments and Spacecraft Charging for Lunar Programs

Space systems interacting with the space plasma environment charge to potentials of a few tens of volts positive in interplanetary space or on the lunar surface in daylight, a few hundred volts negative in the dark lunar plasma wake and in some regions of the Earth s radiation belts, and to multiple kilovolt negative potentials for worst case conditions in the Earth s magnetosphere near geostationary orbit. Good design practices are required to assure that space systems operate successfully in these environments without detrimental effects due to transient currents and insulator failure produced by electrostatic discharges. Cold lunar environments in particular are challenging because detrimental effects of charging are often exacerbated by cold, highly resistive dielectrics which can integrate charge for long periods of time. We will describe the cold plasma and energetic particle environments relevant to lunar missions responsible for surface and bulk charging of space systems and discuss program requirements under development for assuring that systems operate successfully in these environments.

Minow, Joseph I.↗

Multidirectional Cosmic Ray Ion Detector for Deep Space CubeSats

Understanding the nature of anisotropy of solar energetic protons (SEPs) and galactic cosmic ray (GCR) fluxes in the interplanetary medium is crucial in characterizing time-dependent radiation exposure in interplanetary space for future exploration missions. NASA Glenn Research Center has proposed a CubeSat-based instrument to study solar and cosmic ray ions in lunar orbit or deep space. The objective of Solar Proton Anisotropy and Galactic cosmic ray High Energy Transport Instrument (SPAGHETI) is to provide multi-directional ion data to further understand anisotropies in SEP and GCR flux. The instrument is to be developed using large area detectors fabricated from high density, high purity silicon carbide (SiC) to measure linear energy transfer (LET) of ions. Stacks of these LET detectors are arranged in a CubeSat at orthogonal directions to provide multidirectional measurements. The low-noise, thermally-stable nature of silicon carbide and its radiation tolerance allows the multidirectional array of detector stacks to be packed in a 6U CubeSat without active cooling. A concept involving additional coincidence/anticoincidence detectors and a high energy Cherenkov detector is possible to further expand ion energy range and sensitivity.

Extraterrestrial Radiation↗