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NASA NTRS1996

STS-77 Flight Day 10

On this tenth day of the STS-77 mission, the flight crew, Cmdr. John H. Casper, Pilot Curtis L. Brown, Jr., and Mission Specialists Andrew S.W. Thomas, Ph.D., Daniel W. Bursch, Mario Runco, Jr., and Marc Garneau, Ph.D., perform a routine check of the shuttle's flight control surfaces and reaction control system jets, wrap up work with a number of scientific investigations, and begin securing the cabin for the trip back to Earth. Most experiments aboard the shuttle have been completed and stowed away, although a few will operate throughout the night and be deactivated once the crew wakes. Crew members Andy Thomas, a native of Australia, and Marc Garneau, a Canadian, each receive special greetings today as STS-77 nears its end. South Australia Premier Dean Brown called Thomas with congratulations early this morning as the shuttle passed above Brown's office in Adelaide, Australia, Thomas' hometown. Later, Canadian Prime Minister Jean Chretien called Garneau to congratulate him on the mission and the joint Canadian Space Agency and NASA experiments that were conducted.

Source record↗
NASA NTRSDate not supplied

Design, Development, and Use of a Lunar Lander Simulation for NASA's Artemis Program

This paper describes the design, development, and initial use of a generalized and configurable lunar lander simulation to support NASA’s Artemis Program. This simulation is being developed for the Crew Compartment Office (CrewCo) in the Human Landing Systems (HLS) program and is called the HLS CrewCo Lander Simulation (HCLS). The HCLS provides insight into the challenges associated with returning humans to the Moon and the particular difficulties of operating at the Lunar South Pole. The simulation models a generalized integrated lunar landing spacecraft based on a government reference design but can and has been adapted to model vendor specific designs as well. The simulation architecture and tool sets provide a flexible framework that allows for quickly prototyping and evaluating various aspects of a piloted lunar landing system. This includes the modeling of all principal human controlled flight phases: rendezvous and docking with crew transfer systems; docked orbital outpost operations; undocking and lunar transfer; lunar orbital operations; lunar deorbit, descent, and landing (DDL); lunar surface operations; lunar ascent; and return to the orbital outpost. The flexibility of the simulation allows for the integrated evaluation of potential vehicle subsystems, crew displays, guidance and control modes, and trajectory designs. The purpose of the HCLS is not to design the ideal lunar lander, but rather to understand and the strengths and weaknesses of vehicle design choices. This paper describes the basic simulation architecture and discusses the tool sets used to develop the HCLS. This includes a number of open source tool sets and publicly available data sets. This paper also describes some of the early use cases and findings. The primary focus of early HCLS use has been on the manual piloting task to safely get the crew to the desired landing site in case of a failure in the automated guidance system. Several guidance modes and cues have been implemented which allow a pilot to manually fly the vehicle to the targeted landing site starting anywhere from powered descent initiation. It has been a valuable tool for understanding what is required to manually fly a lunar lander as well as giving a sense of the vehicle dynamics, which are much different than anything that is flown on Earth. A number of experienced test pilots have participated in manual piloting evaluations using the HCLS and provided valuable feedback on the piloting task which has been very beneficial to NASA and the HLS program.

James Michael Gentile↗
NASA NTRS1972

Probable solar flare doses encountered on an interplanetary mission as calculated by the MCFLARE code

The computer program, MCFLARE, uses Monte Carlo methods to simulate solar flare occurrences during an interplanetary space voyage. The total biological dose inside a shielded crew compartment due to the flares encountered during the voyage is determined. The computer program evaluates the doses obtained on a large number of trips having identical trajectories. From these results, a dose D sub p having a probability p of not being exceeded during the voyage can be determined as a function of p for any shield material configuration. To illustrate the use of the code, a trip to Mars and return is calculated, and estimated doses behind several thicknesses of aluminum shield and water shield are presented.

Lahti, G. P.↗
NASA NTRS1979

Particle dynamics associated with the space environment

A major factor in dust dynamics in a microgravity environment is the absence of settling; hence, Spacelab air will contain larger particles than a comparable laboratory on earth. In addition, the presence of low level acceleration fluctuations (thruster firings, crew motions, etc.) could inhibit dust removal by surface scavenging. Because of the presence of larger particles, aerosol dynamics at larger Reynolds numbers must be considered. An accurate drag coefficient for spherical particles was developed for the higher Reynolds number phenomena. A general graphic correlation for the drag coefficient as a function of Reynolds and Knudsen numbers was developed based on currently available drag data for spheres. The general equations that govern dust dynamics were reviewed.

Sandborn, V. A.↗
NASA NTRS1986

Elements of a Mars transportation system

Earth to Mars transportation requirements are derived for a permanent Mars base of 20 people operating in the 2035 time frame. In order to satisfy these requirements, various transportation modes are developed assuming an existing space infrastructure including propellant tankers, crew and consumable transfer vehicles, orbital facilities and extraterrestrial propellant factories. These transportation modes are compared with respect to total propellant requirements, number of vehicles required, flight times, frequency of opportunity and several other characteristics. Directions for further studies and analysis are indicated.

Nock, K. T.↗
NASA NTRS1988

The Traffic-Alert and Collision Avoidance System (TCAS) in the glass cockpit

This volume contains the contributions of the participants in the NASA Ames Research Center workshop on the traffic-alert and collision avoidance system (TCAS) implementation for aircraft with cathode ray tube (CRT) or flat panel displays. To take advantage of the display capability of the advanced-technology aircraft, NASA sponsored this workshop with the intent of bringing together industry personnel, pilots, and researchers so that pertinent issues in the area could be identified. During the 2-day workshop participants addressed a number of issues including: What is the optimum format for TCAS advisories. Where and how should maneuver advisories be presented to the crew. Should the maneuver advisories be presented on the primary flight display. Is it appropriate to have the autopilot perform the avoidance maneuver. Where and how should traffic information be presented to the crew. Should traffic information be combined with weather and navigation information. How much traffic should be shown and what ranges should be used. Contained in the document are the concepts and suggestions produced by the workshop participants.

Chappell, Sheryl L.↗
NASA NTRS2011

Estimating the Loss of Crew and Loss of Mission for Crew Spacecraft

Once the US Space Shuttle retires in 2011, the Russian Soyuz Launcher and Soyuz Spacecraft will comprise the only means for crew transportation to and from the International Space Station (ISS). The U.S. Government and NASA have contracted for crew transportation services to the ISS with Russia. The resulting implications for the US space program including issues such as astronaut safety must be carefully considered. Are the astronauts and cosmonauts safer on the Soyuz than the Space Shuttle system? Is the Soyuz launch system more robust than the Space Shuttle? The Soyuz launcher has been in operation for over 40 years. There have been only two loss of life incidents and two loss of mission incidents. Given that the most recent incident took place in 1983, how do we determine current reliability of the system? Do failures of unmanned Soyuz rockets impact the reliability of the currently operational man-rated launcher? Does the Soyuz exhibit characteristics that demonstrate reliability growth and how would that be reflected in future estimates of success? NASA s next manned rocket and spacecraft development project will have to meet the Agency Threshold requirements set forth by NASA. The reliability targets are currently several times higher than the Shuttle and possibly even the Soyuz. Can these targets be compared to the reliability of the Soyuz to determine whether they are realistic and achievable? To help answer these questions this paper will explore how to estimate the reliability of the Soyuz Launcher/Spacecraft system, compare it to the Space Shuttle, and its potential impacts for the future of manned spaceflight. Specifically it will look at estimating the Loss of Crew (LOC) and Loss of Mission (LOM) probability using historical data, reliability growth, and Probabilistic Risk Assessment techniques used to generate these numbers.

Lutomski, Michael G.↗
NASA NTRS2015

Design, Fabrication, and Testing of a Composite Rack Prototype in Support of the Deep Space Habitat Program

In support of the Deep Space Habitat project a number of composite rack prototypes were developed, designed, fabricated and tested to various extents ( with the International Standard Payload Rack configuration, or crew quarters, as a baseline). This paper focuses specifically on a composite rack prototype with a direct tie in to Space Station hardware. The outlined prototype is an all composite construction, excluding metallic fasteners, washers, and their associated inserts. The rack utilizes braided carbon composite tubing for the frame with the sidewalls, backwall and flooring sections utilizing aircraft grade composite honeycomb sandwich panels. Novel additively manufactured thermoplastic joints and tube inserts were also developed in support of this effort. Joint and tube insert screening tests were conducted at a preliminary level. The screening tests allowed for modification, and enhancement, of the fabrication and design approaches, which will be outlined. The initial joint tests did not include mechanical fasteners. Adhesives were utilized at the joint to composite tube interfaces, along with mechanical fasteners during final fabrication (thus creating a stronger joint than the adhesive only variant). In general the prototype was focused on a potential in-space assembly approach, or kit-of-parts construction concept, which would not necessarily require the inclusion of an adhesive in the joint regions. However, given the tie in to legacy Station hardware (and potential flight loads with imbedded hardware mass loadings), the rack was built as stiff and strong as possible. Preliminary torque down tests were also conducted to determine the feasibility of mounting the composite honeycomb panels to the composite tubing sections via the additively manufactured tube inserts. Additional fastener torque down tests were also conducted with inserts (helicoils) imbedded within the joints. Lessons learned are also included and discussed.

Smith, Russ↗
NASA NTRS2018

Miniature Exercise Device-2 (MED-2): Preliminary ISS Evaluation Results for a Compact Motorized Resistive and Aerobic Rowing Exercise Device

Future human missions beyond Low Earth Orbit (LEO) will require onboard equipment to provide exercise capabilities for the crew to counter the adverse physiological effects of long-duration microgravity. To accomplish this within the physical constraints of a space vehicle or transit module, a single miniature device that provides both resistive and aerobic exercise modalities is required. To meet this need, Johnson Space Center’s (JSC) Software, Robotics, and Simulation Division (ER) developed the Miniature Exercise Device-2 (MED-2). MED-2 integrates a torque-controlled servomotor and a series-elastic actuator to provide highly-controllable load profiles and a large magnitude output performance in a very small package. This innovative technology is derived from years of JSC/ER design, development and operational experience with cutting-edge robotics, motor controllers, software and actuator/sensor miniaturization, including Robonaut 2 and MED-1. MED-2 was presented at the 2016 ISS R&D Conference. This is an update now that the last of six crewmembers will have completed planned MED-2 sessions on the International Space Station (ISS) in May 2018.Current state-of-the-art ISS exercise equipment consists of two treadmills, a resistive exercise device and two cycle ergometers with a total mass of several thousand pounds and a total volume of several cubic yards. This equipment has proven vital to mitigate the musculoskeletal and cardiovascular degradation effects of microgravity. However, due to the large operational volume and mass of these ISS devices, tailoring them for smaller vehicles, such as Orion, is not possible. In addition, each of the current ISS devices targets a single specific modality. Compared to the existing spaceflight (and even terrestrial) exercise equipment, MED-2 is a new archetype altogether. The combined features of compact size, multi-modality and high-performance is attributable to its innovative series elastic actuator and motor controller. Following its arrival on ISS in 2016, MED-2 was evaluated in two parts. The first and shorter evaluation was an engineering functional checkout of the hardware. As this was a novel exercise device previously never used on ISS, the initial checkout assessed the operation of the hardware and ensured the motion and dynamic range of the crew did not present any collision or other hazards. The second portion of the study collected the heart rates, kinematics and utilized operational volumes of six astronauts to determine the quality of both the resistive and aerobic exercise modalities as delivered by MED-2. Investigators from JSC Biomedical Research and Environmental Science Division (SK) and Glenn Research Center are currently evaluating the data and preparing preliminary results. For the resistive exercise modality, MED-2 demonstrated a range of constant resistive loads from 10-150 lbf. With a displacement range of 84 inches, the MED-2 accommodates users from 5th percentile Japanese female through 95th percentile American male for all of its certified exercises. The displacement measurement accuracy has also been verified within 2.5 percent full range. The crew was able to successfully perform all prescribed resistive exercises, except Goblet Squats which were not feasible with a constant load profile. For the aerobic exercise modality, MED-2 simulated a rowing motion with prescribed and user-selected resistance levels. It has demonstrated rates up to 60 strokes per minute on the ground. MED-2 loads and displacements performance are the same as those cited for the resistive modality. Although each of the crew was able to perform the prescribed aerobic rowing sets, there was considerable variability in the rowing motion among different crewmembers. Also, as expected, the crew was unable to get the full benefits of a typical terrestrial rowing stroke because the current configuration does not allow the user to reach past their feet. These observations have already informed the requirements for other microgravity rowing devices currently in development. One of the unique features of the MED-2 device is the intuitive touch-screen control system. This One Portal graphical user interface (GUI) was developed based on JSC/ER’s heritage knowledge and experience of developing and sustaining the current ISS exercise equipment. Through this interface, the crew easily performed prepared prescriptions as well as had the ability to adjust exercise modality, load and other exercise details such as number of repetitions and number of sets. This touch-screen and GUI fulfilled the MED-2 project goal to simplify the interaction between the user and the device. Furthermore, the extent to which MED-2 utilizes a touchscreen and GUI to control exercise equipment is unmatched among the existing ISS exercise devices. As a motorized device, MED-2 technology can provide a customizable force profile that can be varied as a function of strap displacement, strap velocity or a combination of these and other variables. During 2017, JSC/ER developed and flight-certified a resistive exercise algorithm that mimics the 1-G inertial effects of free-weights and enables adjustable eccentric-to-concentric loading ratios. Subsequent development will explore varying the load profiles and incorporating additional exercises beyond the current list of certified movements.

Exercise↗
NASA NTRSDate not supplied

Human-Autonomy Teaming Research in Support of m:N Operations

Since 2019, the NASA and industry partners have been involved in research focused on a novel paradigm for operations of remotely piloted aircraft. This paradigm involves multiple people sharing a fleet of multiple vehicles between them. Referred to as m:N (pronounced “em-to-en”), this configuration describes a ratio where m is the number of operators and N is the number of vehicles. Through force and asset multiplication, the m:N concept seeks to enable a scalable and resilient operation of remotely crewed vehicles. The primary means of obtaining such a robust operation is through allowing a flexible crew of variable size to dynamically attend to the needs of assets in while performing real-time operator workload management. It is in that sense that assets are shared between operators: as needed (such as in events of elevated workload) an operator in an m:N context can “handoff” the responsibility for some amount of assets, nh < N, to be absorbed by the m – 1 crew members on staff. At some time later, these nh assets could be returned to their original owner or they may be further distributed to other crew if called for by the mission. During this panel, I will elaborate on the research activity undertaken by the Human-Autonomy Teaming (HAT) Laboratory at NASA Ames Research Center over the previous three years. The studies conducted by the HAT Lab range from interviews with subject matter experts, a cognitive walkthrough, a task analysis, and two simulation experiments to-date. During experimentation, pilots made use of an advanced Ground Control Station developed by the HAT Lab and industry partners to simulate m:N operations in two large, metropolitan areas of Southern California: Los Angeles and San Diego. Further experimentation planned over the next few years. Results from our research to-date indicates that pilots of a moderately sized fleet of about a dozen remotely crewed aircraft adequately maintained safety performance and situation awareness of their aircraft, even when presented with unexpected situations of heightened workload.

multi-vehicle control↗
NASA NTRS2015

Preparing for Mars: The Evolvable Mars Campaign 'Proving Ground' Approach

As the National Aeronautics and Space Administration (NASA) prepares to extend human presence beyond Low Earth Orbit, we are in the early stages of planning missions within the framework of an Evolvable Mars Campaign. Initial missions would be conducted in near-Earth cis-lunar space and would eventually culminate in extended duration crewed missions on the surface of Mars. To enable such exploration missions, critical technologies and capabilities must be identified, developed, and tested. NASA has followed a principled approach to identify critical capabilities and a "Proving Ground" approach is emerging to address testing needs. The Proving Ground is a period subsequent to current International Space Station activities wherein exploration-enabling capabilities and technologies are developed and the foundation is laid for sustained human presence in space. The Proving Ground domain essentially includes missions beyond Low Earth Orbit that will provide increasing mission capability while reducing technical risks. Proving Ground missions also provide valuable experience with deep space operations and support the transition from "Earth-dependence" to "Earth-independence" required for sustainable space exploration. A Technology Development Assessment Team identified a suite of critical technologies needed to support the cadence of exploration missions. Discussions among mission planners, vehicle developers, subject-matter-experts, and technologists were used to identify a minimum but sufficient set of required technologies and capabilities. Within System Maturation Teams, known challenges were identified and expressed as specific performance gaps in critical capabilities, which were then refined and activities required to close these critical gaps were identified. Analysis was performed to identify test and demonstration opportunities for critical technical capabilities across the Proving Ground spectrum of missions. This suite of critical capabilities is expected to provide the foundation required to enable a variety of possible destinations and missions consistent with the Evolvable Mars Campaign.. The International Space Station will be used to the greatest extent possible for exploration capability and technology development. Beyond this, NASA is evaluating a number of options for Proving Ground missions. An "Asteroid Redirect Mission" will demonstrate needed capabilities (e.g., Solar Electric Propulsion) and transportation systems for the crew (i.e., Space Launch System and Orion) and for cargo (i.e., Asteroid Redirect Vehicle). The Mars 2020 mission and follow-on robotic precursor missions will gather Mars surface environment information and will mature technologies. NASA is considering emplacing a small pressurized module in cis-lunar space to support crewed operations of increasing duration and to serve as a platform for critical exploration capabilities testing (e.g., radiation mitigation; extended duration deep space habitation). In addition, "opportunistic mission operations" could demonstrate capabilities not on the Mars critical path that may, nonetheless, enhance exploration operations (e.g., teleoperations, crew assisted Mars sample return). The Proving Ground may also include "pathfinder" missions to test and demonstrate specific capabilities at Mars (e.g., entry, descent, and landing). This paper describes the (1) process used to conduct an architecture-driven technology development assessment, (2) exploration mission critical and supporting capabilities, and (3) approach for addressing test and demonstration opportunities encompassing the spectrum of flight elements and destinations consistent with the Evolvable Mars Campaign.

Bobskill, Marianne R.↗
NASA NTRS1993

Multicultural factors in the space environment - Results of an international shuttle crew debrief

There is increasing interest and concern about the multicultural and multinational factors which might negatively affect adjustment and performance of Space Station Freedom (SSF) crews, living and working for long periods of time in the space environment. To begin identifying potential problem areas, a crew debrief questionnaire (called an 'International Crew Debrief') was mailed to U.S. astronauts who flew on Shuttle missions between 1981-1990 with one or more crewmembers from other countries. There were 20 U.S. astronauts who flew on international space missions; 9 of these responded to the questionnaire, for a return rate of 45 percent. There were 42 incidents reported: 9 in the preflight period; 26 inflight; and 7 in the postflight period. Most of these incidents were rated as having a low or medium impact, but five of the inflight incidents were rated to have a 'high' mission impact. A number of causes for the problems were listed, and are discussed. Debrief respondents provided useful and timely recommendations on preflight training which may help facilitate the integration of multinational crews, and prevent multicultural or multinational factors from interfering with mission operations.

Santy, Patricia A.↗
NASA NTRSDate not supplied

Crew Scheduling Performance

As NASA considers long-duration exploration missions (LDEMs), it is envisioned that crew will behave more autonomously as compared to low-Earth orbit missions. The necessary shift of Ops Planners’ complete management of scheduling and planning to provide flexibility for crew to manage their own schedule in real-time requires significant research and investigation in evaluation of concepts of operations, of software tools to support tasks, and of crew performance to complete scheduling tasks. Our research objective is to characterize the human performance envelope for the task of planning and scheduling (crew self-scheduling), develop countermeasures to mitigate adverse performance effects due to plan complexity, and inform performance standards and guidelines based on research results. In our efforts to understand and characterize scheduling performance of crew members, we have conducted subject matter expert interviews to obtain feedback on scheduling plan complexity drivers and plan goodness. Following the pilot study conducted last year, we designed a study and have begun remote human subject testing to evaluate non-expert human performance, workload, and situational awareness for the task of planning and scheduling. This study investigates the effects of the number and type of constraints on human performance, and the differences in scheduling metrics between scheduling and rescheduling tasks. Subject testing is currently in progress, and we aim to collect data from approximately thirty subjects. We will summarize the methods used and impacts of the number and type of scheduling constraints. We will also present lessons learned as well as relevant results of the study.

crew scheduling↗
NASA NTRS2010

Regenerative (Regen) ECLSS Operations Water Balance

In November 2008, the Water Regenerative System racks were launched aboard Space Shuttle flight, STS-126 (ULF2) and installed and activated on the International Space Station (ISS). These racks, consisting of the Water Processor Assembly (WPA) and Urine Processor Assembly (UPA), completed the installation of the Regenerative (Regen) ECLSS systems which includes the Oxygen Generator Assembly (OGA) that was launched 2 years prior. With the onset of active water management on the US segment of the ISS, a new operational concept was required, that of "water balance." Even more recently, in 2010 the Sabatier system came online which converts H2 and CO2 into water and methane. The Regen ECLSS systems accept condensation from the atmosphere, urine from crew, and processes that fluid via various means into potable water which is used for crew drinking, building up skip-cycle water inventory, and water for electrolysis to produce oxygen. Specification rates of crew urine output, condensate output, O2 requirements, toilet flush water and drinking needs are well documented and used as a general plan when Regen ECLSS came online. Spec rates are useful in long term planning, however, daily or weekly rates are dependent on a number of variables. The constantly changing rates created a new challenge for the ECLSS flight controllers, who are responsible for operating the ECLSS systems onboard ISS. This paper will review the various inputs to rate changes and inputs to planning events, including but not limited to; crew personnel makeup, Regen ECLSS system operability, vehicle traffic, water containment availability, and Carbon Dioxide Removal Assembly (CDRA) capability. Along with the inputs that change the various rates, the paper will review the different systems, their constraints and finally the operational means by which flight controllers manage this new challenge of "water balance."

Tobias, Barry↗
NASA NTRS2014

Toward Single Pilot Operations: The Impact of the Loss of Non-Verbal Communication on the Flight Deck

Since the 1950s, the crew required to fly transport category aircraft has been reduced from five to two. NASA is currently exploring the feasibility of a further reduction to one pilot. In this study we examine the effects of separating the pilots on crew interaction. The results are consistent with earlier research on decision-making between remote groups. Pilots strongly prefer face-to-face interactions; however, we could find no impact of separation on their ultimate decisions. There were a number of areas in which separation negatively affected communications. We discuss possible mitigations for these areas.

Single Pilot Operations↗
NASA NTRS2004

Special Purpose Crew Restraints for Teleoperation

With permanent human presence onboard the International Space Station (ISS), and long duration space missions being planned for the moon and Mars, humans will be living and working in microgravity over increasingly long periods of time. In addition to weightlessness, the confined nature of a spacecraft environment results in ergonomic challenges such as limited visibility, and access to the activity area. These challenges can result in prolonged periods of unnatural postures for the crew, ultimately causing pain, injury, and loss of productivity. Determining the right set of human factors requirements and providing an ergonomically designed environment is crucial to mission success. While a number of general purpose restraints have been used on ISS (handrails, foot loops), experience has shown that these general purpose restraints may not be optimal, or even acceptable for some tasks that have unique requirements. For example, some onboard activities require extreme stability (e.g., glovebox microsurgery), and others involve the use of arm, torso and foot movements in order to perform the task (e-g. robotic teleoperation); standard restraint systems will not work in these situations. The Usability Testing and Analysis Facility (WAF) at the NASA Johnson Space Center began evaluations of crew restraints for these special situations by looking at NASAs Robonaut. Developed by the Robot Systems Technology Branch, Robonaut is a humanoid robot that can be remotely operated through a tetepresence control system by an operator. It was designed to perform work in hazardous environments (e.g., Extra Vehicular Activities). A Robonaut restraint was designed, modeled for the population, and ultimately tested onboard the KC-135 microgravity aircraft. While in microgravity, participants were asked to get in and out of the restraint from different locations, perform maximum reach exercises, and finally to teleoperate Robonaut while in the restraint. The sessions were videotaped, and participants completed a questionnaire at the end of each flight day. Results from this evaluation are being used to develop the human factors design requirements for teleoperation tasks in microgravity.

Whitmore, Mihriban↗
NASA NTRS2018

Differences in Pre and Post Vascular Patterning Within Retinas from ISS Crew Members and Head-Down Tilt (HDT) Subjects by VESGEN Analysis

Accelerated research by NASA has investigated the significant risks incurred during long-duration missions in microgravity for Space Flight-Associated Neuro-ocular Syndrome (SANS, formerly known as Visual Impairments associated with Increased Intracranial Pressure, VIIP) [1]. For our study, NASA's VESsel GENeration Analysis (VESGEN) was used to investigate the role of retinal blood vessels in the etiology of SANS/VIIP. The response of retinal vessels to microgravity was evaluated in astronaut crew members pre and post flight to the International Space Station (ISS), and compared to the response of retinal vessels in healthy volunteers to 6deg head-down tilt during 70 days of bed rest (HDTBR). For the study, we are testing the hypothesis that long-term cephalad fluid shifts resulting in ocular and visual impairments are necessarily mediated in part by retinal blood vessels, and therefore are accompanied by structural adaptations of the vessels. METHODS: Vascular patterns in the retinas of crew members and HDTBR subjects extracted from 30deg infrared (IR) Heidelberg Spectralis images collected pre/postflight and pre/post HDTBR, respectively, were analyzed by VESGEN (patent pending). VESGEN is a mature, automated software developed as a research discovery tool for progressive vascular diseases in the retina and other tissues. The multi-parametric VESGEN analysis generates maps of branching arterial and venous trees quantified by parameters such as the fractal dimension (Df, a modern measure of vascular space-filling capacity), vessel diameters, and densities of vessel length and number classified into specific branching generations according to vascular physiological branching rules. The retrospective study approved by NASA's Institutional Review Board included the analysis of bilateral retinas in eight ISS crew members monitored by routine occupational surveillance and six HDTBR subjects (NASA FARU Campaign 11, for example). The VESGEN analysis was conducted in a blinded fashion, with IR retinal images masked to the subject's identity, ophthalmic and clinical characteristics, and to the temporal sequence of image collection. To complete our study, VESGEN results will be analyzed statistically and correlated with other ophthalmic and medical findings. RESULTS: Preliminary results for changes in the pre to post status of vascular patterning in the retinas of crew members and HDTBR subjects are interestingly opposite. By Df and other vascular branching measures, the space-filling capacity of arterial and venous trees decreased in the majority of crew members (11/16 retinas). In contrast, vascular densities increased in HDTBR subjects by the same parameters (6/10 retinas). To conclude the study, biostatistics and medical analyses will be conducted to quantify and draw conclusions about how the changes associated with flight compare to those associated with HDTBR. CONCLUSIONS: Vascular densities appeared to decrease in the retinas of ISS crew members and increase in HDTBR subjects. Differences in arterial and venous response to cephalad fluid shifts induced by ISS and HDTBR may have resulted from a long-duration conditioning phenomenon (for example, 6-month ISS missions compared to 70 days HDTBR), or the presence of gravity in HDTBR compared to microgravity on the ISS. In addition, increased and decreased vessel diameters for Crew Members and HDTBR, respectively, are subject to limits of im

Vascular↗
NASA NTRS1974

The reliability impact of mission abort strategies on redundant flight computer systems

This correspondence presents a reliability model for a redundant flight computer system with standby sparing, taking into account various mission abort strategies. A mission rule to initiate a mission abort after a predetermined number of detected computer failures and to return to earth with the remaining computers is shown to result in: (1) little improvement of crew safety unless computer error coverage is nearly perfect, and (2) significant degradation in mission success whenever coverage is high.

Filene, R. J.↗