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At least 343 records · Page 19

The Natural Products Magnetic Resonance Database (NP-MRD) for 2025

The Natural Products Magnetic Resonance Database or NP-MRD (https://np-mrd.org) is a comprehensive, freely accessible, web-based resource for the deposition, distribution, extraction and retrieval of nuclear magnetic resonance (NMR) data on natural products. The NP-MRD was initially established to support compound de-replication and data dissemination for the natural products community. However, that community has now grown to include many users from the metabolomics, microbiomics, foodomics and nutrition science fields. Indeed, since its launch in 2021, the NP-MRD has expanded enormously in size, scope and popularity. The current version of NP-MRD now contains nearly 7X more compounds (281,859 vs. 40,908) and 7X more NMR spectra (5.1 million vs. 817,000) than the first release. More specifically, an additional 4.6 million predicted spectra and another 11,000 spectra simulated from experimental chemical shifts were deposited into the database. Likewise, the number of NMR raw spectral data depositions has grown from a 165 spectra per year to more than 10,000 per year. As a result of this expansion, the number of monthly webpage views has grown from 55 to 20,000 and the number of monthly visitors has increased from 7 to 2500. To address this growth and to better support the expanding needs of its diverse community of users, many additional improvements to the NP-MRD have been made. These include significant enhancements to the data submission process, important improvements to the visualization and display of NMR spectra, notable updates to the database’s spectral search utilities and useful additions to support better NMR spectral analysis/prediction. Significant efforts have also been undertaken to remediate and update many of NP-MRD’s database entries. This manuscript describes these database improvements and expansion efforts, along with how they have been implemented and what future upgrades to the NP-MRD are planned.

Artifical Intelligence↗

PCM picture transmission.

PCM picture transmission, pseudorandom scanning, noise, bandwidth compression and digital simulation

BANDWIDTH↗

Construction and testing of a Scanning Laser Radar (SLR), phase 2

The scanning laser radar overall system is described. Block diagrams and photographs of the hardware are included with the system description. Detailed descriptions of all the subsystems that make up the scanning laser radar system are included. Block diagrams, photographs, and detailed optical and electronic schematics are used to help describe such subsystem hardware as the laser, beam steerer, receiver optics and detector, control and processing electronics, visual data displays, and the equipment used on the target. Tests were performed on the scanning laser radar to determine its acquisition and tracking performance and to determine its range and angle accuracies while tracking a moving target. The tests and test results are described.

Flom, T.↗

The measurement of driver describing functions in simulated steering control tasks

Measurements of driver describing functions in steering control tasks have been made using a driving simulator. The task was to regulate against a random crosswind gust input on a straight roadway, in order to stay in the center of the lane. Although driving is a multiloop task in general, the forcing function and situation were configured so that an inner-loop visual cue feedback of heading angle of heading rate would dominate, and the driver's response was interpreted to be primarily single-loop. The driver describing functions were measured using an STI describing function analyzer. Three replications for each subject showed good repeatability within a subject. There were some intersubject differences as expected, but the crossover frequencies, effective time delays, and stability margins were generally consistent with the prior data and models for similar manual control tasks. The results further confirm the feasibility of measuring human operator response properties in nominal control tasks with full (real-world) visual field displays.

Weir, D. H.↗

Development and validation of a piloted simulation of a helicopter and external sling load

A generalized, real time, piloted, visual simulation of a single rotor helicopter, suspension system, and external load is described and validated for the full flight envelope of the U.S. Army CH-54 helicopter and cargo container as an example. The mathematical model described uses modified nonlinear classical rotor theory for both the main rotor and tail rotor, nonlinear fuselage aerodynamics, an elastic suspension system, nonlinear load aerodynamics, and a loadground contact model. The implementation of the mathematical model on a large digital computing system is described, and validation of the simulation is discussed. The mathematical model is validated by comparing measured flight data with simulated data, by comparing linearized system matrices, eigenvalues, and eigenvectors with manufacturers' data, and by the subjective comparison of handling characteristics by experienced pilots. A visual landing display system for use in simulation which generates the pilot's forward looking real world display was examined and a special head up, down looking load/landing zone display is described.

Shaughnessy, J. D.↗

Event-driven displays for manipulator control

The problem of constructing event-related information displays from multidimensional data generated by proximity, force-torque and tactile sensors integrated with the terminal device of a remotely controlled manipulator is considered. Event-driven displays are constructed by using appropriate algorithms acting on sensory data in real time. Event-driven information displays lessen the operator's workload and improve control performance. The paper describes and discusses several event-driven display examples that were implemented in the JPL teleoperator project, including a brief outline of the data handling system which drives the graphics display in real time. The paper concludes with a discussion of future plans to integrate event-driven displays with visual (TV) information.

Bejczy, A. K.↗

Displays for supervisory control of manipulators

The problem of displaying information generated by sensors attached to the terminal device of a remotely controlled manipulator is considered. The sensors under consideration are proximity, force-torque, tactile and slip-page sensors. The paper describes and evaluates several examples that have been implemented in the JPL teleoperator project using audio and graphic displays of information generated by four proximity sensors attached to a manipulator end effector. Design schemes are also discussed related to the display of information generated by a six-dimensional force-torque sensor, a multipoint proportional tactile sensor, and a directional slippage sensor. The paper concludes with a discussion of future integrated displays of visual (TV) and handbased sensor information.

Bejczy, A. K.↗

Utilizing the dust streak-dryline intersection phenomenon in severe local storm forecasting

Several characteristics of a major dust storm on 20 February 1976 are presented. Four primary areas of discussion are considered: dust storm characteristics; comparisons between the cell detection capabilities of the geosynchronous satellite and radar; the use of the NASA Atmospheric and Oceanographic Information Processing System (an interactive image processing system) for interactive display of visual and IR digital data to obtain qualitative and quantitative results on specific dust cloud and cloud top characteristics; and evidence that the intersection downwind of dust clouds (streaks) with the dryline can be used to forecast the initial storm development on the dryline and that the dust clouds detected on 20 February 1976 are a reflection of upper tropospheric speed maxima, which according to McNulty (1978) and others, are associated with rapid severe convective local storm development.

Anthony, R. W.↗

Experiments using electronic display information in the NASA terminal configured vehicle

The results of research experiments concerning pilot display information requirements and visualization techniques for electronic display systems are presented. Topics deal with display related piloting tasks in flight controls for approach-to-landing, flight management for the descent from cruise, and flight operational procedures considering the display of surrounding air traffic. Planned research of advanced integrated display formats for primary flight control throughout the various phases of flight is also discussed.

Morello, S. A.↗

Medical diagnosis system and method with multispectral imaging

A skin diagnosis system includes a scanning and optical arrangement whereby light reflected from each incremental area (pixel) of the skin is directed simultaneously to three separate light filters, e.g., IR, red, and green. As a result, the three devices simultaneously produce three signals which are directly related to the reflectance of light of different wavelengths from the corresponding pixel. These three signals for each pixel after processing are used as inputs to one or more output devices to produce a visual color display and/or a hard copy color print, for one usable as a diagnostic aid by a physician.

Anselmo, V. J.↗

Research through simulation

The design of the computer operating system at Langley Research Center allows for concurrent support of time-critical simulations and background analytical computing on the same machine. Signal path interconnections between computing hardware and flight simulation hardware is provided to allow up to six simulation programs to be in operation at one time. Capabilities and research applications are discussed for the: (1) differential maneuvering simulator; (2) visual motion simulator; (3) terminal configured vehicle simulator; (4) general aviation aircraft simulator; (5) general purpose fixed based simulator; (6) transport simulator; (7) digital fly by wire simulator; (8) general purpose fighter simulator; and (9) the roll-up cockpit. The visual landing display system and graphics display system are described and their simulator support applications are listed.

Copeland, J. L.↗

Virtual reality in medical education and assessment

The NASA Johnson Space Center (JSC)/LinCom Corporation, the University of Texas Medical Branch at Galveston (UTMB), and the Galveston Independent School District (GISD) have teamed up to develop a virtual visual environment display (VIVED) that provides a unique educational experience using virtual reality (VR) technologies. The VIVED end product will be a self-contained educational experience allowing students a new method of learning as they interact with the subject matter through VR. This type of interface is intuitive and utilizes spatial and psychomotor abilities which are now constrained or reduced by the current two dimensional terminals and keyboards. The perpetual challenge to educators remains the identification and development of methodologies which conform the learners abilities and preferences. The unique aspects of VR provide an opportunity to explore a new educational experience. Endowing medical students with an understanding of the human body poses some difficulty challenges. One of the most difficult is to convey the three dimensional nature of anatomical structures. The ideal environment for addressing this problem would be one that allows students to become small enough to enter the body and travel through it - much like a person walks through a building. By using VR technology, this effect can be achieved; when VR is combined with multimedia technologies, the effect can be spectacular.

Sprague, Laurie A.↗

Landstat 7 Views the World

The technical innovations of precise numerical radiometry, spectral differentiation and seasonally repetitive monitoring, introduced by the Landsat series of satellites, created a new measurement approach for terrestrial monitoring. The Landsat 7 mission, successfully initiated on April 15, 1999, reflects significant progress in realizing the scientific potential of this measurement strategy. Substantial improvements in calibration procedures, both prior to launch and during normal operations, have been accomplished to insure long-term stability in the acquired spectral radiometry. For the first time, Landsat 7 will be operated with a long-term data acquisition plan that will insure, barring national emergencies, that substantially cloud-free, seasonal coverage will be recorded and archived in the US for all land areas of the globe. The expected outcome of these efforts is a rapid improvement in our understanding of the Earth system, as well as conceptual knowledge that will underpin commercial application of this technology. The Cape Town 2000 Symposium will take place approximately nine months after the Landsat 7 satellite and instrument completed its engineering checkout phase and was placed in its final orbit in late June, 1999. Thus, this presentation will provide a timely status report, in a significant international setting, regarding the early on-orbit performance of the Landsat 7 spacecraft, the ETM+ instrument, and the long-term data acquisition strategy that has been implemented. The latest data display and visualization techniques will be utilized to present this significant new source of Earth observation data.

Williams, Darrel L.↗