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All sourcesNASA NTRSDOE OSTI
DOE OSTI2022

Low-Energy Physics in Neutrino LArTPCs

In this white paper, we outline some of the scientific opportunities and challenges related to detection and reconstruction of low-energy (less than 100 MeV) signatures in liquid argon time-projection chamber (LArTPC) detectors. Key takeaways are summarized as follows. 1) LArTPCs have unique sensitivity to a range of physics and astrophysics signatures via detection of event features at and below the few tens of MeV range. 2) Low-energy signatures are an integral part of GeV-scale accelerator neutrino interaction final states, and their reconstruction can enhance the oscillation physics sensitivities of LArTPC experiments. 3) BSM signals from accelerator and natural sources also generate diverse signatures in the low-energy range, and reconstruction of these signatures can increase the breadth of BSM scenarios accessible in LArTPC-based searches. 4) Neutrino interaction cross sections and other nuclear physics processes in argon relevant to sub-hundred-MeV LArTPC signatures are poorly understood. Improved theory and experimental measurements are needed. Pion decay-at-rest sources and charged particle and neutron test beams are ideal facilities for experimentally improving this understanding. 5) There are specific calibration needs in the low-energy range, as well as specific needs for control and understanding of radiological and cosmogenic backgrounds. 6) Novel ideas for future LArTPC technology that enhance low-energy capabilities should be explored. These include novel charge enhancement and readout systems, enhanced photon detection, low radioactivity argon, and xenon doping. 7) Low-energy signatures, whether steady-state or part of a supernova burst or larger GeV-scale event topology, have specific triggering, DAQ and reconstruction requirements that must be addressed outside the scope of conventional GeV-scale data collection and analysis pathways.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗
DOE OSTI2025

First demonstration of a TES based cryogenic Li 2 MoO 4 detector for neutrinoless double beta decay search

Cryogenic calorimetric experiments to search for neutrinoless double-beta decay (0vββ) are highly competitive, scalable and versatile in isotope. The largest planned detector array, CUPID, is comprised of about 1500 individual Li 2 100 MoO 4 detector modules with a further scale up envisioned for a follow up experiment (CUPID-1T). In this article, we present a novel detector concept targeting this second stage with a low impedance TES based readout for the Li 2 MoO 4 absorber that is easily mass-produced and lends itself to a multiplexed readout. We present the detector design and results from a first prototype detector operated at the NEXUS shallow underground facility at Fermilab. The detector is a 2-cm-side cube with 21 g mass that is strongly thermally coupled to its readout chip to allow rise-times of ~0.5 ms. This design is more than one order of magnitude faster than present NTD based detectors and is hence expected to effectively mitigate backgrounds generated through the pile-up of two independent two neutrino decay events coinciding close in time. Together with a baseline resolution of 1.95 keV (FWHM) these performance parameters extrapolate to a background index from pile-up as low as 5 • 10 –6 counts/keV/kg/yr in CUPID size crystals. The detector was calibrated up to the MeV region showing sufficient dynamic range for 0vββ searches. In combination with a SuperCDMS HVeV detector this setup also allowed us to perform a precision measurement of the scintillation time constants of Li 2 MoO 4 , which showed a primary component with a fast O(20 μs) time scale. Similar content being viewe

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗
DOE OSTI2025

Burning conditions and transportation pathways determine biomass-burning aerosol properties in the Ascension Island marine boundary layer

Abstract. African biomass-burning aerosol (BBA) in the southeast Atlantic Ocean (SEA) marine boundary layer (MBL) is an important contributor to Earth's radiation budget, yet its representation remains poorly constrained in regional and global climate models. Data from the Layered Atlantic Smoke Interactions with Clouds (LASIC) field campaign on Ascension Island (7.95° S, 14.36° W) provide insight into how burning conditions, fuel type, transport pathways, and atmospheric processing affect the chemical, microphysical, and optical properties of BBA between June and September 2017. A total of 10 individual plume events characterize the seasonal evolution of the BBA properties. Early-season inefficient fires, determined by low refractory black carbon to above-background carbon monoxide mixing ratios (rBC : ΔCO), led to enhanced concentrations of organic- and sulfate-rich aerosols. Mid-season efficient fires, determined by higher rBC : ΔCO values, led to rBC-enriched BBA. A mix of efficient and inefficient fires later in the season resulted in conflicting BBA properties. Prolonged transport (∼ 10 d) through the MBL and lower free troposphere (FT) facilitated chemical and aqueous-phase processing, which led to a reduction in organic aerosol mass concentrations. This resulted in lower organic aerosol (OA) to rBC (OA : rBC) mass ratios (2–5) in the MBL compared to higher values (5–15) in the nearby FT. These atmospheric and cloud oxidation processes yield more light-absorbing BBA and explain the notably low single-scattering albedo at 530 nm (SSA530) values (< 0.80) observed in the MBL. This study establishes a robust correlation between SSA530 and OA : rBC across the MBL and FT, underscoring the dependency of optical properties on chemical composition.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
DOE OSTI2024

Deployment and performance of a Low-Energy-Threshold Skipper-CCD inside a nuclear reactor

Charge Coupled Devices (CCD) are being used for reactor neutrino experiments and have already demonstrated their potential in constraining new physics models. The prospect of a Skipper-CCD experiment looking for standard and beyond standard model (BSM) physics in a nuclear reactor has been evaluated for different benchmark scenarios. Here, we report the first installation of a 2-g Skipper-CCD inside the containment building of a 2 GW th nuclear power plant and analyze its performance throughout its first 18 months of operation. The sensor was successfully deployed at Atucha II, in Argentina, 12 meters away from the center of the reactor core. We discuss the challenges involved in the commissioning of the detector and present data acquired during reactor ON and reactor OFF periods, with the sensor functioning with a sub-electron readout noise of 0.17 e - . Based on an exposure of 56.8 g day reactor ON and two reactor OFF data sets with a total exposure of 118.1 g day we characterize the system and evaluate the sensitivity to CEvNS. We achieved a background rate of 33 kdru and a low threshold of 45 eV ee . The ongoing efforts to improve sensitivities to CEvNS and BSM interaction are also discussed.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗
DOE OSTI2026

Cosmogenic neutron production in water at SNO+

Accurate measurement of the cosmogenic muon-induced neutron yield is crucial for constraining a significant background in a wide range of low-energy physics searches. Although previous underground experiments have measured this yield across various cosmogenic muon energies, SNO+ is uniquely positioned due to its exposure to one of the highest average cosmogenic muon energies at 364 GeV. Using ultrapure water, we have determined a neutron yield of 𝑌 𝑛 = (3.3⁢8$^{+0.23}_{−0.30}$) × 10 −4 cm 2 g −1 𝜇 −1 at SNO+. Comparison with simulations demonstrates clear agreement with the FLUKA neutron production model, highlighting discrepancies with the widely used GEANT 4 model. Furthermore, this measurement reveals a lower cosmogenic neutron yield than that observed by the SNO experiment, which used heavy water under identical muon flux conditions. This result provides new evidence that nuclear structure and target material composition significantly influence neutron production by cosmogenic muons, offering fresh insight with important implications for the design and background modeling of future underground experiments.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗
DOE OSTI2024

Evaluation of the Impact of Concentration and Extraction Methods on the Targeted Sequencing of Human Viruses from Wastewater

Sequencing human viruses in wastewater is challenging due to their low abundance compared to the total microbial background. This study compared the impact of four virus concentration/extraction methods (Innovaprep, Nanotrap, Promega, and Solids extraction) on probe-capture enrichment for human viruses followed by sequencing. Different concentration/extraction methods yielded distinct virus profiles. Innovaprep ultrafiltration (following solids removal) had the highest sequencing sensitivity and richness, resulting in the successful assembly of several near-complete human virus genomes. However, it was less sensitive in detecting SARS-CoV-2 by digital polymerase chain reaction (dPCR) compared to Promega and Nanotrap. Across all preparation methods, astroviruses and polyomaviruses were the most highly abundant human viruses, and SARS-CoV-2 was rare. These findings suggest that sequencing success can be increased using methods that reduce nontarget nucleic acids in the extract, though the absolute concentration of total extracted nucleic acid, as indicated by Qubit, and targeted viruses, as indicated by dPCR, may not be directly related to targeted sequencing performance. Further, using broadly targeted sequencing panels may capture viral diversity but risks losing signals for specific low-abundance viruses. Overall, this study highlights the importance of aligning wet lab and bioinformatic methods with specific goals when employing probe-capture enrichment for human virus sequencing from wastewater.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2022

Gravitational wave background from mergers of large primordial black holes

The Peters formula, which tells how the coalescence time of a binary system emitting gravitational radiation is determined by the initial size and shape of the elliptic orbit, is often used in estimating the merger rate of primordial black holes and the gravitational wave background from the mergers. Valid as it is in some interesting scenarios, such as the analysis of the LIGO-Virgo events, the Peters formula fails to describe the coalescence time if the orbital period of the binary exceeds the value given by the formula. This could underestimate the event rate of mergers that occur before the cosmic time t ~ 10 13 s. As a result, the energy density spectrum of the gravitational wave background could develop a peak, which is from mergers occurring at either t ~ 10 13 s (for black holes with mass M ≳ 10 8 M ⊙ ) or t ~ 10 26 (M/M ⊙ ) -5/3 s (for 10 5 M ⊙ ≲ M ≲ 10 8 M ⊙ ). This can be used to constrain the fraction of dark matter in primordial black holes (denoted by f) if potential probes (such as SKA and U-DECIGO) do not discover such a background, with the result f ≲ 10 -6 –10 -4 for the mass range 10– 10 9 M ⊙ . Finally, we then consider the effect of mass accretion onto primordial black holes at redshift z ~ 10, and find that the merger rate could drop significantly at low redshifts. The spectrum of the gravitational wave background thus gets suppressed at the high-frequency end. This feature might be captured by future detectors such as ET and CE for initial mass M = Script $\mathcal{O}$(10–100) M ⊙ with f ≳ 10 -4 .

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2024

Developing a data-driven method to constrain the antiproton background in the Mu2e experiment

The Mu2e experiment will search for CLFV neutrinoless coherent muon to electron conversion in the field of an Al nucleus. The expected signal is a 104.97 MeV/c monochromatic $e^-$ (CE). CE-like $e^-$’s could also come from $\bar{p}$’s annihilating in the Stopping Target (ST). The background induced by $\bar{p}$’s is expected to be low but has a large systematic uncertainty. It cannot be suppressed by the time window cut used to reduce the prompt background. However, $p\bar{p}$ annihilation in the ST is the only source of events in the Mu2e detector with multiple tracks coming from the ST, simultaneous in time, each with a momentum in the signal window region. We exploited this unique feature and developed algorithms to identify and reconstruct multi-track events. This paper discusses the status and prospects of this data-driven method to constrain the $\bar{p}$ background at Mu2e.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗
DOE OSTI2024

The Simons Observatory: Design, Optimization, and Performance of Low-Frequency Detectors

The Simons Observatory (SO) is a cosmic microwave background (CMB) experiment located in the Atacama Desert in Chile that will make precise temperature and polarization measurements over six spectral bands ranging from 27 to 285 GHz. Three small aperture telescopes (SATs) and one large aperture telescope (LAT) will house ~60,000 detectors and cover angular scales between one arcminute and tens of degrees. We present the performance of the dichroic, low-frequency (LF) lenslet-coupled sinuous antenna transition-edge sensor (TES) bolometer arrays with bands centered at 27 and 39 GHz. The LF focal plane will primarily characterize Galactic synchrotron emission as a critical part of foreground subtraction from CMB data. We will discuss the design, optimization, and current testing status of these pixels.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2024

Confirmation of the spectral excess in DAMIC at SNOLAB with skipper CCDs

Here, we present results from a 3.25 kg–day target exposure of two silicon charge-coupled devices (CCDs), each with 24 megapixels and skipper readout, deployed in the DAMIC setup at SNOLAB. With a reduction in pixel readout noise of a factor of 10 relative to the previous detector, we investigate the excess population of low-energy events in the CCD bulk previously observed above expected backgrounds. We address the dominant systematic uncertainty of the previous analysis through a depth fiducialization designed to reject surface backgrounds on the CCDs. The measured bulk ionization spectrum confirms the presence of an excess population of low-energy events in the CCD target with characteristic rate of ~7 events per kg-day and electron-equivalent energies of ~80 eV, whose origin remains unknown.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗
DOE OSTI2025

Detection of Isotopes in Urban Source Search Low-Count Gamma Spectra Using Hopfield Neural Networks

Source search campaigns involve measurements of background gamma-ray spectra with a mobile detector-spectrometer traveling along arbitrarily chosen trajectories over a wide screening area. Radiation counts are typically measured with a tellurium-doped sodium iodide [NaI(Tl)] scintillator detector-spectrometer in short acquisition intervals, usually 1 s. The objective is to detect orphan isotopes with half-lives shorter than those of the isotopes in the natural background. In principle, radioisotopes can be identified by their unique gamma emission spectrum. However, detecting orphan isotopes in search data is challenging because low counts measured in short acquisition intervals result in incomplete spectral lines. In this study, we investigate the performance of a Hopfield neural network (HNN) that implements an auto-associative memory for the detection of isotopes of interest in an urban search campaign. The HNN is trained on one example of gamma spectra with well-resolved spectral lines of each isotope of interest. During testing, the auto-associative memory implementation of the HNN processes low-count gamma spectra with partially complete isotopic lines by matching incoming measurements to the closest one of its memory-stored patterns. The testing database consisted of almost 10 000 1-s gamma spectra, including measurements of orphan isotopes 137 Cs, 241 Am, and 131 I, obtained during two urban search surveys with a NaI(Tl) detector. The performance of the HNN detection algorithm was evaluated using precision, recall, and F1 scores, and benchmarked with a multiple linear regression (MLR) identification algorithm. In conclusion, the test results demonstrate that HNN outperforms MLR in the detection of all the isotopes of interest.

Auto associative memory↗
DOE OSTI2025

Charged Current Coherent Pion Production Cross-Section Measurement at MicroBooNE

Coherent pion production, characterized by a neutrino interacting with an entire nucleus without breaking it apart, results in a forward-going muon, pion, and a low-momentum recoil nucleus. By leveraging an improved understanding of particle identification and background parameterization, we aim to achieve a new level of sensitivity to coherent interactions at low neutrino energy. The outcome of this analysis will contribute to ongoing efforts to model neutrino nucleus interactions accurately in neutrino oscillation studies and beyond Standard Model searches in MicroBooNE and future experiments, such as DUNE. We present progress towards a measurement of charged current coherent pion production cross-section on argon with the MicroBooNE liquid argon time projection chamber detector. This measurement will use MicroBooNE's full dataset collected from the Booster Neutrino Beam with a total exposure of \( 1.3 \times 10^{21} \) protons-on-target and average neutrino energy of 0.8 GeV.

Hussain, Adil [Kansas State U.]↗
DOE OSTI2022

Behavioral and neuroinflammatory changes caused by glyphosate: Base herbicide in mice offspring

Abstract Background Glyphosate is a pesticide considered of low toxicity, but scientific evidences show it can be harmful to health. This study aimed to evaluate the toxicity in mice offspring exposed to glyphosate‐based herbicide (GBH) during the intrauterine period. Methods Female matrices received glyphosate 0.3 mg/kg daily per oral throughout the gestational period, which was variable between 18 and 22 days. From the 25th until the 28th days post‐birth, mice offspring were subjected to behavioral tests, and the prefrontal cortex was processed for immunohistochemical analysis. Results Two significant behavioral changes were observed: anxiety in the GLIF0.3 group, increase in the behavior burying marbles in the marble‐burying test and hyperactivity, expressed by the significant increase of the crossing number in the open field test. The increased microglia, TNF‐alpha, and astrocyte expression were also observed in the prefrontal cortex of offspring treated with GLIF0.3. Conclusion Exposure to GBH during mice intrauterine development induces hyperactive and anxious behavior, evidencing neuroinflammation.

de Castro Vieira Carneiro, Carla Larissa↗
DOE OSTI2023

Intensity of sample processing methods impacts wastewater SARS-CoV-2 whole genome amplicon sequencing outcomes

Wastewater SARS-CoV-2 surveillance has been deployed since the beginning of the COVID-19 pandemic to monitor the dynamics in virus burden in local communities. Genomic surveillance of SARS-CoV-2 in wastewater, particularly efforts aimed at whole genome sequencing for variant tracking and identification, are still challenging due to low target concentration, complex microbial and chemical background, and lack of robust nucleic acid recovery experimental procedures. The intrinsic sample limitations are inherent to wastewater and are thus unavoidable. Here, we use a statistical approach that couples correlation analyses to a random forest-based machine learning algorithm to evaluate potentially important factors associated with wastewater SARS-CoV-2 whole genome amplicon sequencing outcomes, with a specific focus on the breadth of genome coverage. We collected 182 composite and grab wastewater samples from the Chicago area between November 2020 to October 2021. Samples were processed using a mixture of processing methods reflecting different homogenization intensities (HA + Zymo beads, HA + glass beads, and Nanotrap), and were sequenced using one of the two library preparation kits (the Illumina COVIDseq kit and the QIAseq DIRECT kit). Technical factors evaluated using statistical and machine learning approaches include sample types, certain sample intrinsic features, and processing and sequencing methods. The results suggested that sample processing methods could be a predominant factor affecting sequencing outcomes, and library preparation kits was considered a minor factor. Finally, a synthetic SARS-CoV-2 RNA spike-in experiment was performed to validate the impact from processing methods and suggested that the intensity of the processing methods could lead to different RNA fragmentation

60 APPLIED LIFE SCIENCES↗
DOE OSTI2024

Helium-electrospray improves sample delivery in X-ray single-particle imaging experiments

Abstract Imaging the structure and observing the dynamics of isolated proteins using single-particle X-ray diffractive imaging (SPI) is one of the potential applications of X-ray free-electron lasers (XFELs). Currently, SPI experiments on isolated proteins are limited by three factors: low signal strength, limited data and high background from gas scattering. The last two factors are largely due to the shortcomings of the aerosol sample delivery methods in use. Here we present our modified electrospray ionization (ESI) source, which we dubbed helium-ESI (He-ESI). With it, we increased particle delivery into the interaction region by a factor of 10, for 26 nm-sized biological particles, and decreased the gas load in the interaction chamber corresponding to an 80% reduction in gas scattering when compared to the original ESI. These improvements have the potential to significantly increase the quality and quantity of SPI diffraction patterns in future experiments using He-ESI, resulting in higher-resolution structures.

Science & Technology - Other Topics↗
DOE OSTI2021

Projected sensitivities of the LUX-ZEPLIN experiment to new physics via low-energy electron recoils

LUX-ZEPLIN is a dark matter detector expected to obtain world-leading sensitivity to weakly-interacting massive particles interacting via nuclear recoils with a ∼7-tonne xenon target mass. This paper presents sensitivity projections to several low-energy signals of the complementary electron recoil signal type: 1) an effective neutrino magnetic moment, and 2) an effective neutrino millicharge, both for 𝑝⁢𝑝-chain solar neutrinos, 3) an axion flux generated by the Sun, 4) axionlike particles forming the Galactic dark matter, 5) hidden photons, 6) mirror dark matter, and 7) leptophilic dark matter. World-leading sensitivities are expected in each case, a result of the large 5.6 t 1000 d exposure and low expected rate of electron-recoil backgrounds in the <100 keV energy regime. A consistent signal generation, background model and profile-likelihood analysis framework is used throughout.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗
DOE OSTI2022

Modeling Urban Acoustic Noise in the Las Vegas, NV Region

Ambient infrasound noise in quiet, rural environments has been extensively studied and well-characterized through noise models for several decades. More recently, creating noise models for high-noise rural environments has also become an area of active research. However, far less work has been done to create generalized low-frequency noise models for urban areas. The high ambient noise levels expected in cities and other highly populated areas means that these environments are regarded as poor locations for acoustic sensors, and historically, sensor deployment in urban areas were avoided for this reason. However, there are several advantages to placing sensors in urban environments, including convenience of deployment and maintenance, and increasingly, necessity, as more previously rural areas become populated. This study seeks to characterize trends in low-frequency urban noise by creating a background noise model for Las Vegas, NV, using the Las Vegas Infrasound Array (LVIA): a network of eleven infrasound sensors deployed throughout the city. Data included in this study spans from 2019 to 2021 and provides a largely uninterrupted record of noise levels in the city from 0.1–500 Hz, with only minor discontinuities on individual stations. We organize raw data from the LVIA sensors into hourly power spectral density (PSD) averages for each station and select from these PSDs to create frequency distributions for time periods of interest . These frequency distributions are converted into probability density functions (PDFs), which are then used to evaluate variations in frequency and amplitude over daily to seasonal timescale s. In addition to PDFs, the median, 5 th percentile, and 95 th percentile amplitude values are calculated across the entire frequency range. This methodology follows a well-established process for noise model creation.

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTAN↗
DOE OSTI2024

Characterization of High-Temperature SiPM Noise

Introduction • Background: Silicon photomultipliers (SiPMs) are compact, low-power, and high-efficiency detectors that are increasingly used in radiation detection applications like medical imaging and nuclear safeguards. The have advantages of PMTs because they are smaller, operate at lower voltages, and offer high photon detection efficiency. • Challenges: SiPMs suffer from increased dark count rate (DCR) and optical crosstalk (OCT), which degrades performance. • Purpose of study: This study compares the Advansid ASD-NUV3S-P-40, Broadcom AFBR-S4K33C0147L, and Onsemi MicroFJ-30035-TSVTR under four different temperatures to compare their performance in harsh environments.

Fritchie, Jacob↗