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In 1992, Dr. Wes Huntress challenged the JPL staff to undertake the first of NASA's new Discovery Program missions; Pathfinder.
Heterotrophic microorganisms in marine sediments produce extracellular enzymes to hydrolyze organic macromolecules, so their products can be transported inside the cell and used for energy and growth. Therefore, extracellular enzymes may mediate the fate of organic carbon in sediments. The Baltic Sea Basin is a primarily depositional environment with high potential for organic matter preservation. The potential activities of multiple organic carbon-degrading enzymes were measured in samples obtained by the International Ocean Discovery Program Expedition 347 from the Little Belt Strait, Denmark, core M0059C. Potential maximum hydrolysis rates (V max ) were measured at depths down to 77.9mbsf for the following enzymes: alkaline phosphatase, β- d -xylosidase, β- d -cellobiohydrolase, N-acetyl-β- d -glucosaminidase, β-glucosidase, α-glucosidase, leucyl aminopeptidase, arginyl aminopeptidase, prolyl aminopeptidase, gingipain, and clostripain. Extracellular peptidase activities were detectable at depths shallower than 54.95mbsf, and alkaline phosphatase activity was detectable throughout the core, albeit against a relatively high activity in autoclaved sediments. β-glucosidase activities were detected above 30mbsf; however, activities of other glycosyl hydrolases (β-xylosidase, β-cellobiohydrolase, N-acetyl-β-glucosaminidase, and α-glucosidase) were generally indistinguishable from zero at all depths. These extracellular enzymes appear to be extremely stable: Among all enzymes, a median of 51.3% of enzyme activity was retained after autoclaving for an hour. We show that enzyme turnover times scale with the inverse of community metabolic rates, such that enzyme lifetimes in subsurface sediments, in which metabolic rates are very slow, are likely to be extraordinarily long. A back-of-the-envelope calculation suggests enzyme lifetimes are, at minimum, on the order of 230days, and may be substantially longer. These results lend empirical support to the hypothesis that a population of subsurface microbes persist by using extracellular enzymes to slowly metabolize old, highly degraded organic carbon.
It is the Policy of NASA s Office of Space Science to emphasize and encourage the addition of Participating Scientist Programs (PSP s) to broaden the scientific impact of missions. A Participating Scientist Program for the STARDUST Mission: STARDUST is the fourth Discovery mission, and it is the first sample return mission selected within the Discovery Program. The STARDUST Spacecraft will fly through the coma of comet PIwildt-2 in early January 2004, and return the samples to the Earth in January 2006. The Principal Investigator of the STARDUST mission, Dr. Donald Brownlee, has generously requested the implementation of a PSP for STARDUST in order to provide more community participation in the initial characterization and analysis of the samples from PIwildt-2. In particular participating scientists will fill out the membership of the Preliminary Examination Team (PET) called for in the original 1994 STARDUST proposal accepted by NASA in 1995. The work of the PET will be organized around major subdiscipline areas such as mineralogy and petrology, isotopic abundances, and elemental composition. There will be leaders for each of these areas, and also a number of team members within each. Support will be commensurate with the level of participation.
The Deep Impact Spacecraft was launched on January 12, 2005 as part of NASA's Discovery Program as a radical mission to excavate the interior of a comet. The Spacecraft consisted of two separate entities known as the Flyby and the Impactor, which were commanded to separate prior to comet rendezvous with comet 9P/Tempel 1. The overall mission was deemed a success on July 4, 2005, as the 370-kg Impactor collided with the comet at 10.2 km/s. This event was captured using the camera and infrared spectrometer on the Flyby spacecraft, along with ground-based observatories. Since this event, the Flyby spacecraft has been in hibernation mode and has received only a small amount of maintenance. The Deep Impact Program was managed by the Jet Propulsion Laboratory (JPL), led by Dr. Michael A'Hearn from the University of Maryland in College Park, and built by Ball Aerospace & Technologies Corp. in Boulder, Colorado.
The Lunar Prospector mission is the first dedicated NASA lunar mapping mission since the Apollo Orbiter program which was flown over 25 years ago. Competitively selected under the NASA Discovery Program, Lunar Prospector was launched on January 7, 1998 on the new Lockheed Martin Athena 2 launch vehicle. The mission design of Lunar Prospector is characterized by a direct minimum energy transfer trajectory to the moon with three scheduled orbit correction maneuvers to remove launch and cislunar injection errors prior to lunar insertion. At lunar encounter, a series of three lunar orbit insertion maneuvers and a small circularization burn were executed to achieve a 100 km altitude polar mapping orbit. This paper will present the design of the Lunar Prospector transfer, lunar insertion and mapping orbits, including maneuver and orbit determination strategies in the context of mission goals and constraints. Contingency plans for handling transfer orbit injection and lunar orbit insertion anomalies are also summarized. Actual flight operations results are discussed and compared to pre-launch support analysis.
The Mars Program institutes the Mars Scout Missions in order to address science goals in the program not otherwise covered in baseline Mars plans. Mars Scout missions will be Principal-Investigator (PI) led science missions. Analogous to the Discovery Program, PI-led investigations optimize the use of limited resources to accomplish focused science and allow the flexibility to quickly respond to discoveries at Mars. Scout missions also require unique investments in technology and reliance upon Mars-based infrastructure such as telecom relay orbiters. Scouts utilize a two-step competitive process for selection. In Dec, 2002, the Step 2 selections by NASA were announced and then approximately five month studies will result in a selection for flight around August, 2003 for a mission to be launched in 2007.
The Mars program institutes the Mars Scout Missions in order to address science goals in the program not otherwise covered in the baseline Mars plan. Mars Scout Missions will be Principle-Investigator (PI) led science missions. Analogous to the Discovery Program, PI led investigations optimize the use of limited resources to accomplish the best focused science and allow the flexibility to quickly respond to discoveries at Mars. Scout missions also require unique investments in technology and reliance upon Mars-based infrastructure such as telecom relay orbiters.
Recently, the geology of the surface of Vesta has been coming to light. In 1983 Gaffey first began showing maps of the surface geology of Vesta constructed from numerous spectra obtained at different times as the asteroid rotated. By noting the details of spectral variation with rotation, he was able to develop two possible gross-scale geologic maps of Vesta showing the distributions of mafic and ultramafic materials. These maps were published in 1997. Finally, the capabilities of the Hubble Space Telescope were brought to bear on Vesta and images with a resolution of about 50 km were obtained using four different filters by Binzel and co-workers. Maps produced by this team published in 1997 began to reveal the geology of Vesta in sufficient detail that crude interpretations of the geologic history of the asteroid could be attempted. Additionally, in 1993 Binzel and Xu published a study of small asteroids in the region near Vesta in orbital-element space. In this study, they showed that there are a number of asteroids a few kilometers in size with reflectance spectra like that of Vesta that form a trail in orbital-element space from near Vesta to near resonances that can more easily supply material to near-Earth space. Binzel and Xu thus concluded that these small asteroids were spells of Vesta ejected by impact and that some of their brethren had been perturbed to Earth-approaching orbits. They suggested that these latter were the immediate parents of HED meteorites. This seemed to remove a long-standing dynamical objection to Vesta as the HED parent body, as discussed by Wasson and Wetherill in 1979. Within the last few years, NASA has initiated the Discovery program of low-cost, rapid-timescale development, exploration missions. Vesta has been proposed as an object worthy of study by a Discovery mission, although a Vesta mission has not yet been selected. With all the recent activity aimed at studying Vesta and the HED meteorites, and the possibility of a space mission to Vesta, we felt that time was ripe to convene a workshop bringing together astronomers, meteoriticists, and planetary geologists to focus on what could be learned about the geologic evolution of Vesta through integrating astronomical and HED meteorite studies. This, of course, assumes that the HED meteorites are from Vesta, and this issue was specifically addressed (but not resolved) in the workshop. Indeed, it seems likely that this issue can only be resolved by returning samples from Vesta for detailed study on Earth. The workshop was held at the LPI on October 16-18,1996, and was attended by some 70 scientists. Sessions included a set of talks on Earth- and space-based astronomical observations of Vesta plus the evidence pro and con for Vesta being the HED parent body, talks on the petrology and geochemistry of HED meteorites, talks on the formation and dynamics of ejecta from Vesta, talks on the thermal history of asteroids and HED meteorites, volcanic processes and differentiation history, and a short session devoted to possible missions to Vestal By all accounts, the workshop was considered a great success, although this is the opinion of a biased set of observers.
The Clementine Mission, a joint project of the Strategic Defense Initiative Organization (SDIO) and NASA, has been planned primarily to test and demonstrate a suite of lightweight sensors and other lightweight spacecraft components under extended exposure to the space environment. Although the primary objective of the mission is to space-qualify sensors for Department of Defense applications, it was recognized in 1990 that such a mission might also be designed to acquire scientific observations of the Moon and of Apollo asteroid (1620) Geographos. This possibility was explored jointly by SDIO and NASA, including representatives from NASA's Discovery Program Science Working Group, in early 1991. Besides the direct return of scientific information, one of the benefits envisioned from a joint venture was the development of lightweight components for possible future use in NASA's Discovery-class spacecraft. In Jan. 1992, SDIO informed NASA of its intent to fly a 'Deep Space Program Science Experiment,' now popularly called Clementine; NASA then formed an advisory science working group to assist in the early development of the mission. The Clementine spacecraft is being assembled at the Naval Research Laboratory, which is also in charge of the overall mission design and mission operations. Support for mission design is being provided by GSFC and by JPL. NASA's Deep Space Network will be utilized in tracking and communicating with the spacecraft. Following a recommendation of the COMPLEX committee of the Space Science Board, NASA will issue an NRA and appoint a formal science team in early 1993. Clementine is a 3-axis stabilized, 200 kg (dry weight) spacecraft that will be launched on a refurbished Titan-2G. One of the goals has been to build two spacecraft, including the sensors, for $100M. Total time elapsed from the decision to proceed to the launch will be two years.
The Deep Atmosphere Venus Investigation of Noble Gases, Chemistry, and Imaging Plus (DAVINCI+) mission is one of four finalists now in Phase A study as part of the ongoing Discovery Program competition [1-5]. If selected for flight, DAVINCI+ will be the first mission to Venus to incorporate flybys, a descent probe, and an orbital phase into one unified architecture – at the cost of a Discovery mission. The result will be a transformative new understanding of the atmosphere, surface, and evolutionary path of Venus as a once-habitable planet [6] (and model exoplanet) that is now host to a certainly unhabitable surface environment.
STARDUST is the Discovery Program's fourth mission, selected from a field of 28 original proposals.
NASAs Kepler Mission was launched in March 2009 as NASAs first mission capable of finding Earth-size planets orbiting in the habitable zone of Sun-like stars, that range of distances for which liquid water would pool on the surface of a rocky planet. Kepler has discovered over 2200 planets and over 2200 candidate planets, many of them as small as the Earth. Forty nine of these are less than twice the size of Earth and orbit in the habitable zone of their stars, all of which are cooler and significantly smaller than the Sun.Today, Keplers amazing success seems to be a fait accompli to those unfamiliar with her history. But twenty years ago, there were no planets known outside our solar system, and few people believed it was possible to detect tiny Earth-size planets orbiting other stars. Indeed, demonstrating that the science was feasible took four proposals to NASAs Discovery Program and extensive research and laboratory demonstrations. Motivating NASA to select Kepler for launch required a confluence of the right detector technology, advances in signal processing and algorithms, and the power of supercomputing. On August 23 2015 we reported the discovery of Kepler-452b, the first small, possibly rocky planet in the habitable zone of a G2 star very similar to our own. Kepler-452b orbits its star once every 385 days in an orbit just 5 larger than that of Earth. This discovery represents an important step towards finding and characterizing small habitable worlds orbiting Sun-like stars.
A detailed study examines the potential benefits that advanced electric propulsion (EP) technologies offer to the cost-capped missions in NASA's Discovery program. The study looks at potential cost and performance benefits provided by three EP technologies that are currently in development: NASA's Evolutionary Xenon Thruster (NEXT), an Enhanced NSTAR system, and a Low Power Hall effect thruster. These systems are analyzed on three straw man Discovery class missions and their performance is compared to a state of the art system using the NSTAR ion thruster. An electric propulsion subsystem cost model is used to conduct a cost-benefit analysis for each option. The results show that each proposed technology offers a different degree of performance and/or cost benefit for Discovery class missions.
The MESSENGER (Mercury Surface, Space Environment, Geochemistry, and Ranging) spacecraft, planned for launch in March 2004, will perform two flybys of Mercury before entering a year-long orbit of the planet in September 2009. The mission will provide opportunities for detailed characterization of the surface, interior, atmosphere, and magnetosphere of the closest planet to the Sun. The NASA Glenn Research Center and the MESSENGER spacecraft integrator, the Johns Hopkins University Applied Physics Laboratory, have partnered under a Space Act Agreement to characterize a variety of critical components and materials under simulated conditions expected near Mercury. Glenn's Vacuum Facility 6, which is equipped with a solar simulator, can simulate the vacuum and high solar radiation anticipated in Mercury orbit. The MESSENGER test hardware includes a variety of materials and components that are being characterized during the Tank 6 vacuum tests, where the hardware will be exposed to up to 11 suns insolation, simulating conditions expected in Mercury orbit. In 2002, ten solar vacuum tests were conducted, including beginning of life, end of life, backside exposure, and solar panel thermal shock cycling tests. Components tested include candidate solar array panels, sensors, thermal shielding materials, and communication devices. As an example, for the solar panel thermal shock cycling test, two candidate solar array panels were suspended on a lift mechanism that lowered the panels into a liquid-nitrogen-cooled box. After reaching -140 C, the panels were then lifted out of the box and exposed to the equivalent of 6 suns (8.1 kilowatts per square meters). After five cold soak/heating cycles were completed successfully, there was no apparent degradation in panel performance. An anticipated 100-hr thermal shield life test is planned for autumn, followed by solar panel flight qualification tests in winter. Glenn's ongoing support to the MESSENGER program has been instrumental in identifying design solutions and validating thermal performance models under a very aggressive development schedule. The test data have assisted Johns Hopkins engineers in selecting a flight solar array vendor and a thermal shield design. MESSENGER is one in a series of missions in NASA's Discovery Program. Infrared thermography provides data on the thermal gradients in the MESSENGER components during high solar insolation vacuum testing.
The fundamentals of photographic discovery are discussed, and the work at the Palomar Observatory is described including photographic discovery programs elsewhere. The Spacewatch development of CCD-scanning techniques is reviewed. Special searches for objects near the Earth are reported. The existence of four streams among both Earth-approaching asteroids and meteorite-dropping fireballs suggests that at certain times of the year an increase can be expected in both asteroid discoveries and meteoritic events.
Genesis is the fifth mission selected as part of NASA's Discovery Program. The objective of Genesis is to collect solar wind samples for a period of approximately two years while in a halo orbit about the Earth-Sun L I point. At the end of this period, the samples are to be returned to a specific recovery point on the Earth for subsequent analysis. This goal has never been attempted before and presents a formidable challenge in terms of mission design and operations, particularly planning and execution of propulsive maneuvers. To achieve a level of cost-effectiveness consistent with a Discovery-class mission, the Genesis spacecraft design was adapted to the maximum extent possible from designs used on earlier missions, such as Mars Global Surveyor (MGS) and Stardust, another sample collection mission. The spacecraft design for Genesis is shown. Spin stabilization was chosen for attitude control, in lieu of three-axis stabilization, with neither reaction wheels nor accelerometers included. This precludes closed-loop control of propulsive maneuvers and implies that any attitude changes, including spin changes and precessions, will behave like translational propulsive maneuvers and affect the spacecraft trajectory. Moreover, to minimize contamination risk to the samples collected, all thrusters were placed on the side opposite the sample collection canister. The orientation and characteristics of thrusters are indicated. For large maneuvers (>2.5 m/s), two 5 lbf thrusters will be used for delta v, with precession to the burn attitude, followed by spin-up from 1.6 to 10 rpm before the burn and spin down to 1.6 rpm afterwards, then precession back to the original spin attitude. For small maneuvers (<2.5 m/s), no spin change is needed and four 0.2 lbf thrusters are used for Av. Single or double 360 deg. precession changes are required whenever the desired delta v falls inside the two-way turn circle (about 0.4 m/s) based on the mass properties, spin rate and lever arm lengths based on thruster locations. In such instances, delta v resulting from spacecraft precession cannot be used effectively as a component of the desired delta v, and must therefore be removed by precessing at least one complete revolution around the turn circle. To eliminate cross-track execution errors, a second revolution in the opposite direction would also be performed. This paper will address the design of propulsive maneuvers in light of the aforementioned challenges and other constraints. Maneuver design will be performed jointly by the Navigation Team at JPL and the Spacecraft Team at LMA, based on the process indicated . Typical maneuver timelines will be presented which address considerations introduced by attitude changes. These include nutation, which is introduced by precessing or spinning down and must be given sufficient time to damp out prior to execution of subsequent events, as well as sun and earth pointing constraints, which must be considered to ensure sufficient spacecraft power and to minimize telecommunications interruptions, respectively. The paper will include a description of how individual propulsive maneuvers are resolved into components to account for delta v from translational burns and spacecraft attitude changes required to carry out such maneuvers. Contributions to maneuver delta v arising from attitude changes, based on mass properties for the period just after launch, are indicated. Similar curves will be presented spanning all mission phases from launch through return. A set of closed-form equations for resolving maneuver components, base on a specific delta v required for correction or deterministic changes to the spacecraft trajectory will be presented, as well. In addition to nominal maneuvers, special calibration maneuvers are planned to improve open-loop modeling of maneuvers and to reduce execution errors. Uncalibrated execution errors are indicated. Such errors could be reduced by 50% or more over the course of the mission. Special calibrations are of particular importance for the return leg of the mission, since the sample canister must be returned to a specific location within the Utah Test and Training Range (UTTR) for mid-air retrieval. An entry angle tolerance of no less than +/- 0.08 deg. is required to achieve this objective. Biasing of the final return maneuvers coupled with a specific maneuver mode to use a series of well-characterized spin changes to effect these maneuvers is part of the current Genesis baseline mission plan. Another important objective of calibrations is to better characterize precession maneuvers. Such maneuvers are part of most propulsive maneuvers, but are also required periodically to maintain sun-pointing for power or daily during solar-wind pointing during collection periods. Although relatively small, such maneuvers will have a significant cumulative impact on orbit determination, particularly in the halo portion of the mission. The current mission design also calls for three stationkeeping maneuvers during each halo orbit of approximately six months duration. These stationkeeping maneuvers may be sufficiently small that single or double 360 deg. precession changes may be required. Because there are no accelerometers on board the spacecraft, calibration can only be performed with the aid of ground-based radiometric tracking. To establish a high degree of accuracy in characterizing the magnitude of burns, the spacecraft spin axis should be along the line of sight to the Earth, providing Doppler measurements with <1 mm/sec accuracy in S-Band. Emission constraints allow such alignment only during certain portions of the mission when the Earth-spacecraft-sun geometry is favorable. The impact of precessions, or burns at times when geometry is not favorable, can be assessed by reconstruction of the spacecraft trajectory using tracking arcs of several days before and after the event.
Lucy, NASA’s 13th Discovery program mission, launched on October 16, 2021, is enroute to explore the Jupiter-Trojan asteroids situated at the L4 and L5 Lagrange points. Along this trajectory, Lucy will conduct flybys of two main belt asteroids and perform three Earth fly-bys. This paper delves into the Orbit Determination (OD) process during the Dinkinesh flyby, marking Lucy’s inaugural encounter with an asteroid. The Dinkinesh flyby achieved a significant milestone, flawlessly completing the engineering systems checkout. The discussion herein encompasses the OD strategy, setup, and computed OD solutions during operations. The paper further explores the impact of solar conjunction on the OD solutions and decisions and sheds light on the discovery of Selam, a contact binary orbiting Dinkinesh. Preliminary reconstructed trajectories for both Lucy and Dinkinesh, and an initial state of Selam, are presented. The close approach radial distance of Lucy from Dinkinesh was 430.63 km±0.02km in formal uncertainty.
The metastatic tumors of breast cancer lead to the mortality of patients in part due to the failure of chemotherapeutics to reach the brain and emergence of drug resistance. With the increase in drug resistance, we focused on targeting mitochondrial metabolism, which was recently found to be a viable and novel drug target in breast cancer. Here we screened several ligands for anticancer activity in a phenotypic screen using the MTT dye as a marker for cell proliferation. MCF-7 breast cancer cells were treated with compounds in the presence of galactose to ensure mitochondrial interaction by the compounds. The lead compound of our group, NL-1, a thiazolidinedione (TZD), was found to inhibit cell proliferation with an IC{sub 50} of 7.1 μM, whereas its unsaturated derivative CI-987 was more potent with a IC{sub 50} of 3.3 μM. The TZDs were affected by substitution on both the aromatic ring and the TZD warhead. Taken together, these compounds can serve as lead structures for mitochondrial targeted drug discovery programs in breast cancer.