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Human physiological responses to lower body negative pressure /LBNP/, studying presence or absence of change for orthostatic tolerance as function of time
A research program the general objective of which was to measure the effects of various sustained accelerations on the control performance of pilots, was carried out on the Aviation Medical Acceleration Laboratory centrifuge, U.S. Naval Air Development Center, Johnsville, PA. The experimental setup consisted of a flight simulator with the centrifuge in the control loop. The pilot performed his control tasks while being subjected to acceleration fields such as might be encountered by a forward-facing pilot flying an atmosphere entry vehicle. The study was divided into three phases. In one phase of the program, the pilots were subjected to a variety of sustained linear acceleration forces while controlling vehicles with several different sets of longitudinal dynamics. Here, a randomly moving target was displayed to the pilot on a cathode-ray tube. For each combination of acceleration field and vehicle dynamics, pilot tracking accuracy was measured and pilot opinion of the stability and control characteristics was recorded. Thus, information was obtained on the combined effects of complexity of control task and magnitude and direction of acceleration forces on pilot performance. These tests showed that the pilot's tracking performance deteriorated markedly at accelerations greater than about 4g when controlling a lightly damped vehicle. The tentative conclusion was also reached that regardless of the airframe dynamics involved, the pilot feels that in order to have the same level of control over the vehicle, an increase in the vehicle dynamic stability was required with increases in the magnitudes of the acceleration impressed upon the pilot. In another phase, boundaries of human tolerance of acceleration were established for acceleration fields such as might be encountered by a pilot flying an orbital vehicle. A special pilot restraint system was developed to increase human tolerance to longitudinal decelerations. The results of the tests showed that human tolerance of longitudinal deceleration forces was considerably improved through use of the special restraint system.
INTRODUCTION Human exposure data to dynamic loads in spaceflight are sparse not only because very few crewmembers have flown in space, but also because much of the historic data is no longer readily available. Earth and Moon landings of the Apollo missions are unique and valuable for understanding human tolerance in water landing conditions for both short-duration and long-duration crewmembers as well as informing crew tolerance in standing postures during planetary landings. The goal of this task was to find relevant Apollo data to better understand human tolerance in these scenarios, in order to apply this knowledge to future missions. METHODS The goal of this task was to recover time history data from dynamic phases of flight from crewed Apollo missions. The first phase of the task was to search available records at JSC and other centers to locate the appropriate records at the National Archives in Fort Worth, TX. Once the possible data locations were located, it was planned that one researcher would travel to the National Archives in Fort Worth, TX to collect the relevant Apollo data. Once the data was retrieved, they would be digitized for future use and evaluation, and archived within the Human Physiology, Performance, Protection, and Operations (H-3PO) laboratory within the Human Health and Performance Directorate. These data would be used to assess the feasibility and acceptability of current standards and vehicle design requirements for lunar and Mars missions. Additionally, any medical monitoring required, or physiological changes noted in crewmembers based on dynamic loads would be documented for future use. RESULTS Relevant records were found at Ft. Worth, TX and College Park, MD using the National Archives Online Catalog. In addition to the online catalog, an Archives staff member was able to share an additional inventory list of NASA JSC records held in Ft. Worth, TX. Due to COVID-19, NASA has only recently allowed non-mission essential travel. In addition, the National Archives has also been closed to the public since March 2020. Because of this, travel to the National Archives to search records there has not been possible. CONCLUSION The findings include collections at the National Archives at both Ft. Worth, TX and College Park, MD that could possibly hold the data we are looking for. Unfortunately, the descriptions of each collection are very broad. Though we are hopeful that relevant data is stored in one of these collections, we cannot be sure that we will find what we are looking for. At this time, it is not clear when the Archives will reopen to the public or when NASA will allow travel. Travel to the Archives has been postponed, and will be reassessed at a future date.
Orthostatic tolerance is reduced in the heat-stressed human. The purpose of this project was to identify whether skin-surface cooling improves orthostatic tolerance. Nine subjects were exposed to 10 min of 60 degrees head-up tilting in each of four conditions: normothermia (NT-tilt), heat stress (HT-tilt), normothermia plus skin-surface cooling 1 min before and throughout tilting (NT-tilt(cool)), and heat stress plus skin-surface cooling 1 min before and throughout tilting (HT-tilt(cool)). Heating and cooling were accomplished by perfusing 46 and 15 degrees C water, respectively, though a tube-lined suit worn by each subject. During HT-tilt, four of nine subjects developed presyncopal symptoms resulting in the termination of the tilt test. In contrast, no subject experienced presyncopal symptoms during NT-tilt, NT-tilt(cool), or HT-tilt(cool). During the HT-tilt procedure, mean arterial blood pressure (MAP) and cerebral blood flow velocity (CBFV) decreased. However, during HT-tilt(cool), MAP, total peripheral resistance, and CBFV were significantly greater relative to HT-tilt (all P < 0.01). No differences were observed in calculated cerebral vascular resistance between the four conditions. These data suggest that skin-surface cooling prevents the fall in CBFV during upright tilting and improves orthostatic tolerance, presumably via maintenance of MAP. Hence, skin-surface cooling may be a potent countermeasure to protect against orthostatic intolerance observed in heat-stressed humans.
Results of clinical studies of radiation effects on man are used to evaluate space radiation hazards encountered during manned space travel. Considered are effects of photons as well as of mixed fission neutrons and gamma irradiations in establishing body radiosensitivity and tolerance levels. Upper and lower dose-response-time relations for acute radiation syndromes in patients indicate that man is more than sufficiently radioresistant to make the risks of an early radiation effect during one short space mission intangibly small in relation to the other nonradiation risks involved.
The acute radiation syndrome in man is clinically bounded by death at high dose levels and by the prodromal syndrome of untoward physiological effects at minimal levels of clinically effective exposure. As in lower animals, man experiences principally three acute modes of death from radiation exposure (Bond et al., 1965). These are known collectively as the lethal radiation syndromes: central nervous system death, gastrointestinal death, and hematopoietic death. The effect of multiple exposure on lethality, the effect of multiple exposure on hematopoietic recovery, and quantitative aspects of cell and tissue repair are discussed.
Acute and chronic dehydration effects on human tolerance to acceleration stress
Full body support systems - aeroembolism, linear acceleration, human tolerance
Physiological accelerometers - biomechanics, human tolerance, otology, weightlessness
French research on impact and crash - human tolerance, aircraft accidents, ejection seats
Usaf impact acceleration and facilities - aero- space vehicle, biodynamics, human tolerance
Path of body travel - impact studies, biodynamics, human tolerance, automobile accidents
Faa impact research - aviation medicine, human tolerance, acceleration stress, aircraft accidents
Flight safety foundation aviation crash injury studies - human tolerance, acceleration stress
Army impact studies - human tolerance, acceleration stress, aircraft accidents, aviation medicine
Review of nasa impact work - apollo project, human tolerance, acceleration stress