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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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NASA NTRS2010

In Vitro Disease Model of Microgravity Conditioning on Human Energy Metabolism

NASA and its partners are committed to introducing appropriate new technology to enable learning and living safely beyond the Earth for extended periods of time in a sustainable and possibly indefinite manner. In the responsible acquisition of that goal, life sciences is tasked to tune and advance current medical technology to prepare for human health and wellness in the space environment. The space environment affects the condition and function of biological systems from organ level function to shape of individual organelles. The objective of this paper is to study the effect of microgravity on kinetics of drug metabolism. This fundamental characterization is meaningful to (1) scientific understanding of the response of biology to microgravity and (2) clinical dosing requirements and pharmacological thresholds during long term manned space exploration. Metabolism kinetics of the anti-nausea drug promethazine (PMZ) were determined by an in vitro ground model of 3-dimensional aggregates of human hepatocytes conditioned to weightlessness using a rotating wall bioreactor. The authors observed up-regulated PMZ conversion in model microgravity conditions and attribute this to effect to model microgravity conditioning acting on metabolic mechanisms of the cells. Further work is necessary to determine which particular cellular mechanisms are governing the experimental observations, but the authors conclude kinetics of drug metabolism are responsive to gravitational fields and further study of this sensitivity would improve dosing of pharmaceuticals to persons exposed to a microgravity environment.

Snyder, Jessica↗
NASA NTRS2016

Paving the Path for Human Space Exploration: The Challenges and Opportunities

Lauri Hansen, Director of Engineering at NASA Johnson Space Center will discuss the challenges of human space exploration. The future of human exploration begins with our current earth reliant missions in low earth orbit. These missions utilize the International Space Station to learn how to safely execute deep space missions. In addition to serving as an exploration test bed and enabling world class research, the International Space Station enables NASA to build international and commercial partnerships. NASA's next steps will be to enable the commercialization of low earth orbit while concentrating on developing the spacecraft and infrastructure necessary for deep space exploration and long duration missions. The Orion multi-purpose crew vehicle and the Space Launch System rocket are critical building blocks in this next phase of exploration. There are many challenges in designing spacecraft to perform these missions including safety, complex vehicle design, and mass challenges. Orion development is proceeding well, and includes a significant partnership with the European Space Agency (ESA) to develop and build the Service Module portion of the spacecraft. Together, NASA and ESA will provide the capability to take humans further than we have ever been before - 70,000 km past the moon. This will be the next big step in expanding the frontiers of human exploration, eventually leading to human footprints on Mars.

Hansen, Lauri↗
NASA NTRS2020

Hazard Contribution Modes of Machine Learning Components

Amongst the essential steps to be taken towards developing and deploying safe systems with embedded learning-enabled components (LECs) i.e., software components that use ma- chine learning (ML)—are to analyze and understand the con- tribution of the constituent LECs to safety, and to assure that those contributions have been appropriately managed. This paper addresses both steps by, first, introducing the notion of hazard contribution modes (HCMs) a categorization of the ways in which the ML elements of LECs can contribute to hazardous system states; and, second, describing how argumentation patterns can capture the reasoning that can be used to assure HCM mitigation. Our framework is generic in the sense that the categories of HCMs developed i) can admit different learning schemes, i.e., supervised, unsupervised, and reinforcement learning, and ii) are not dependent on the type of system in which the LECs are embedded, i.e., both cyber and cyber-physical systems. One of the goals of this work is to serve a starting point for systematizing L analysis towards eventually automating it in a tool.

Smith, Colin↗
DOE OSTI2024

Infrared-safe energy weighting does not guarantee small nonperturbative effects

Infrared and collinear (IRC) safety has long been used a proxy for robustness when developing new jet substructure observables. This guiding philosophy has been carried into the deep learning era, where IRC-safe neural networks have been used for many jet studies. For graph-based neural networks, the most straightforward way to achieve IRC safety is to weight particle inputs by their energies. However, energy-weighting by itself does not guarantee that perturbative calculations of machine-learned observables will enjoy small nonperturbative corrections. Here, in this paper, we demonstrate the sensitivity of IRC-safe networks to nonperturbative effects, by training an energy flow network (EFN) to maximize its sensitivity to hadronization. We then show how to construct Lipschitz energy flow networks (L-EFNs), which are both IRC safe and relatively insensitive to nonperturbative corrections. We demonstrate the performance of L-EFNs on generated samples of quark and gluon jets, and showcase fascinating differences between the learned latent representations of EFNs and L-EFNs.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗
DOE OSTI2025

Safe and Robust Binary Classification and Fault Detection Using Reinforcement Learning

In this paper, we propose a learning-based method utilizing the Soft Actor-Critic (SAC) algorithm to train a binary Support Vector Machine (SVM) classifier. This classifier is designed to identify valid input spaces in high-dimensional, highly constrained systems while minimizing the total runtime of offline simulations. The simulations adapt their runtime based on the likelihood that a given training input will be informative to the classifier. Furthermore, we introduce a method for using the trained SAC model to predict whether a desired system input is likely to violate constraints, along with a technique to adjust the input as necessary. Additionally, we explore the potential of this model to detect faults or adversarial attacks within the system. The effectiveness of our approach is demonstrated through various simulations of challenging classification problems and a constrained quadrotor model.

Netter, Josh [Georgia Institute of Technology, Atl↗
DOE OSTI2026

Control Room of the Future Testbed Workshop – After-Action Report

The U.S. Department of Energy’s Office of Electricity is supporting a one-year, multi-laboratory effort to define the needs and requirements for a Control Room of the Future testbed, or CROFT. The effort responds to increasing grid complexity driven by large new loads, dynamic generation resources, and the growing adoption of advanced technologies and tools, including artificial intelligence (AI) and machine learning (ML). To support safe, secure, and effective grid modernization, CROFT will focus on how emerging technologies and tools can be rigorously evaluated in realistic operational settings, with attention to human-machine interaction, cognitive load, and workforce readiness. The project team includes Argonne National Laboratory, Idaho National Laboratory, National Laboratory of the Rockies, and Pacific Northwest National Laboratory. As part of the scoping effort, the team conducted two industry-focused workshops: one at DTECH on February 5, 2026, informed by prior industry interviews, and a second on May 4, 2026, adjacent to IEEE T&D. These engagements brought together utilities, vendors, consultants, national laboratories, academia, and government stakeholders to identify and prioritize use cases, barriers, validation needs, data-sharing constraints, and near- and longer-term requirements. This feedback will directly inform CROFT’s architecture and research focus areas, ensuring the testbed is grounded in real-world operational needs and designed to evaluate emerging technologies and tools in realistic control-room environments.

artificial intelligence↗
NASA NTRS1982

Lessons learned - Americans in space

Milestones in the learning process during development of spaceflight capability for different NASA missions are traced from the initial launch of the Mercury escape rocket to the advent of the Shuttle. A detached heat shield on the first manned Mercury orbital flight led to a decision for reentry with retrorockets attached, a situation which demonstrated a need for on-line communications with the spacecraft construction engineers. The Gemini program served to develop EVA techniques and docking procedures essential for the Apollo missions. Apollo 8 circled the moon after only one manned test flight of the equipment due to the success of the first flight. Lunar landing simulation training exposed the astronauts to situations beyond the human ability to respond. The training was justified when computer overload required the pilot to retake manual control of some spacecraft functions during the successful first lunar landing. All lessons previously learned were used to safely return the damaged Apollo 13 to earth. The Skylab missions provided an opportunity to maintain rotating teams of flight controllers on a 24-hr/day basis for periods of months. Finally, the six-year hiatus of U.S. manned space activities between the end of the Skylab missions and the first Shuttle flight provided time for incorporating previous lessons into new procedures, training strategies, and data resources.

Kranz, E.↗
NASA NTRS2015

Space Resource Utilization: Near-Term Missions and Long-Term Plans for Human Exploration

NASA's Human Exploration Plans: A primary goal of all major space faring nations is to explore space: from the Earth with telescopes, with robotic probes and space telescopes, and with humans. For the US National Aeronautics and Space Administration (NASA), this pursuit is captured in three important strategic goals: 1. Ascertain the content, origin, and evolution of the solar system and the potential for life elsewhere, 2. Extend and sustain human activities across the solar system (especially the surface of Mars), and 3. Create innovative new space technologies for exploration, science, and economic future. While specific missions and destinations are still being discussed as to what comes first, it is imperative for NASA that it foster the development and implementation of new technologies and approaches that make space exploration affordable and sustainable. Critical to achieving affordable and sustainable human exploration beyond low Earth orbit (LEO) is the development of technologies and systems to identify, extract, and use resources in space instead of bringing everything from Earth. To reduce the development and implementation costs for space resource utilization, often called In Situ Resource Utilization (ISRU), it is imperative to work with terrestrial mining companies to spin-in/spin-off technologies and capabilities, and space mining companies to expand our economy beyond Earth orbit. In the last two years, NASA has focused on developing and implementing a sustainable human space exploration program with the ultimate goal of exploring the surface of Mars with humans. The plan involves developing technology and capability building blocks critical for sustained exploration starting with the Space Launch System (SLS) and Orion crew spacecraft and utilizing the International Space Station as a springboard into the solar system. The evolvable plan develops and expands human exploration in phases starting with missions that are reliant on Earth, to performing ever more challenging and longer duration missions in cis-lunar space and beyond, to eventually being independent from Earth. The goal is no longer just to reach a destination, but to enable people to work, learn, operate, and live safely beyond the Earth for extended periods of time, ultimately in ways that are more sustainable and even indefinite.

Sanders, Gerald B.↗
NASA NTRS2016

Proving Ground Potential Mission and Flight Test Objectives and Near Term Architectures

NASA is developing a Pioneering Space Strategy to expand human and robotic presence further into the solar system, not just to explore and visit, but to stay. NASA's strategy is designed to meet technical and non-technical challenges, leverage current and near-term activities, and lead to a future where humans can work, learn, operate, and thrive safely in space for an extended, and eventually indefinite, period of time. An important aspect of this strategy is the implementation of proving ground activities needed to ensure confidence in both Mars systems and deep space operations prior to embarking on the journey to the Mars. As part of the proving ground development, NASA is assessing potential mission concepts that could validate the required capabilities needed to expand human presence into the solar system. The first step identified in the proving ground is to establish human presence in the cis-lunar vicinity to enable development and testing of systems and operations required to land humans on Mars and to reach other deep space destinations. These capabilities may also be leveraged to support potential commercial and international objectives for Lunar Surface missions. This paper will discuss a series of potential proving ground mission and flight test objectives that support NASA's journey to Mars and can be leveraged for commercial and international goals. The paper will discuss how early missions will begin to satisfy these objectives, including extensibility and applicability to Mars. The initial capability provided by the launch vehicle will be described as well as planned upgrades required to support longer and more complex missions. Potential architectures and mission concepts will be examined as options to satisfy proving ground objectives. In addition, these architectures will be assessed on commercial and international participation opportunities and on how well they develop capabilities and operations applicable to Mars vicinity missions.

Smith, R. Marshall↗
NASA NTRS2015

Space Resource Utilization: Near-Term Missions and Long-Term Plans for Human Exploration

A primary goal of all major space faring nations is to explore space: from the Earth with telescopes, with robotic probes and space telescopes, and with humans. For the US National Aeronautics and Space Administration (NASA), this pursuit is captured in three important strategic goals: 1. Ascertain the content, origin, and evolution of the solar system and the potential for life elsewhere, 2. Extend and sustain human activities across the solar system (especially the surface of Mars), and 3. Create innovative new space technologies for exploration, science, and economic future. While specific missions and destinations are still being discussed as to what comes first, it is imperative for NASA that it foster the development and implementation of new technologies and approaches that make space exploration affordable and sustainable. Critical to achieving affordable and sustainable human exploration beyond low Earth orbit (LEO) is the development of technologies and systems to identify, extract, and use resources in space instead of bringing everything from Earth. To reduce the development and implementation costs for space resource utilization, often called In Situ Resource Utilization (ISRU), it is imperative to work with terrestrial mining companies to spin-in/spin-off technologies and capabilities, and space mining companies to expand our economy beyond Earth orbit. In the last two years, NASA has focused on developing and implementing a sustainable human space exploration program with the ultimate goal of exploring the surface of Mars with humans. The plan involves developing technology and capability building blocks critical for sustained exploration starting with the Space Launch System (SLS) and Orion crew spacecraft and utilizing the International Space Station as a springboard into the solar system. The evolvable plan develops and expands human exploration in phases starting with missions that are reliant on Earth, to performing ever more challenging and longer duration missions in cis-lunar space and beyond, to eventually being independent from Earth. The goal is no longer just to reach a destination, but to enable people to work, learn, operate, and live safely beyond the Earth for extended periods of time, ultimately in ways that are more sustainable and even indefinite.

Sanders, Gerald B.↗
DOE OSTI2026

Moving from Information Assurance to Functional Assurance with Engineered Controls

Cyber threats to operational technology demand more than traditional IT defenses—they require full-spectrum mission assurance. Cyber-Informed Engineering (CIE) is an approach that embeds engineered controls into system design to ensure critical functions remain safe and reliable, even under attack. Unlike conventional cybersecurity tools, engineered controls act directly on physical processes to prevent unacceptable outcomes such as equipment damage or mission failure. This session will outline the CIE framework and share examples of consequence-based design that deliver true resilience, not just fail-safe behaviors. Attendees will learn how to integrate these principles into the engineering lifecycle to support resilient-by-design architectures and inform emerging standards. This talk sets the stage for the panel discussion on advancing CIE across sectors as digital and physical systems converge.

24 - POWER TRANSMISSION AND DISTRIBUTION↗
NASA NTRS1988

Tethered system/space platform integration - TSS lessons learned

Tethered spacecraft systems must be integrated with their user platforms in a way that allows both to carry out their design functions efficiently and safely. This paper describes the lessons learned about tethered system integration with a space platform from the NASA/PSN Tethered Satellite System. Items discussed include platform attitude control, induced voltage and current control, satellite tracking and tether length measurement, satellite communications and system operations sensitivities. A number of engineering issues yet to be resolved are noted. Tethered systems are complex and require careful design to ensure successful operation.

Rudolph, L. K.↗
NASA NTRS2016

Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders: Evidence Report

In April 2010, President Obama declared a space pioneering goal for the United States in general and NASA in particular. "Fifty years after the creation of NASA, our goal is no longer just a destination to reach. Our goal is the capacity for people to work and learn and operate and live safely beyond the Earth for extended periods of time, ultimately in ways that are more sustainable and even indefinite." Thus NASA's Strategic Objective 1.1 emerged as "expand human presence into the solar system and to the surface of Mars to advance exploration, science, innovation, benefits to humanity, and international collaboration" (NASA 2015b). Any space flight, be it of long or short duration, occurs in an extreme environment that has unique stressors. Even with excellent selection methods, the potential for behavioral problems among space flight crews remain a threat to mission success. Assessment of factors that are related to behavioral health can help minimize the chances of distress and, thus, reduce the likelihood of adverse cognitive or behavioral conditions and psychiatric disorders arising within a crew. Similarly, countermeasures that focus on prevention and treatment can mitigate the cognitive or behavioral conditions that, should they arise, would impact mission success. Given the general consensus that longer duration, isolation, and confined missions have a greater risk for behavioral health ensuring crew behavioral health over the long term is essential. Risk, which within the context of this report is assessed with respect to behavioral health and performance, is addressed to deter development of cognitive and behavioral degradations or psychiatric conditions in space flight and analog populations, and to monitor, detect, and treat early risk factors, predictors and other contributing factors. Based on space flight and analog evidence, the average incidence rate of an adverse behavioral health event occurring during a space mission is relatively low for the current conditions. While mood and anxiety disturbances have occurred, no behavioral emergencies have been reported to date in space flight. Anecdotal and empirical evidence indicate that the likelihood of an adverse cognitive or behavioral condition or psychiatric disorder occurring greatly increases with the length of a mission. Further, while cognitive, behavioral, or psychiatric conditions might not immediately and directly threaten mission success, such conditions can, and do, adversely impact individual and crew health, welfare, and performance.

Slack, Kelley J.↗
NASA NTRS2015

Implementing NASA's Capability-Driven Approach: Insight into NASA's Processes for Maturing Exploration Systems

NASA is engaged in transforming human spaceflight. The Agency is shifting from an exploration-based program with human activities focused on low Earth orbit (LEO) and targeted robotic missions in deep space to a more sustainable and integrated pioneering approach. Through pioneering, NASA seeks to address national goals to develop the capacity for people to work, learn, operate, live, and thrive safely beyond the Earth for extended periods of time. However, pioneering space involves more than the daunting technical challenges of transportation, maintaining health, and enabling crew productivity for long durations in remote, hostile, and alien environments. This shift also requires a change in operating processes for NASA. The Agency can no longer afford to engineer systems for specific missions and destinations and instead must focus on common capabilities that enable a range of destinations and missions. NASA has codified a capability driven approach, which provides flexible guidance for the development and maturation of common capabilities necessary for human pioneers beyond LEO. This approach has been included in NASA policy and is captured in the Agency's strategic goals. It is currently being implemented across NASA's centers and programs. Throughout 2014, NASA engaged in an Agency-wide process to define and refine exploration-related capabilities and associated gaps, focusing only on those that are critical for human exploration beyond LEO. NASA identified 12 common capabilities ranging from Environmental Control and Life Support Systems to Robotics, and established Agency-wide teams or working groups comprised of subject matter experts that are responsible for the maturation of these exploration capabilities. These teams, called the System Maturation Teams (SMTs) help formulate, guide and resolve performance gaps associated with the identified exploration capabilities. The SMTs are defining performance parameters and goals for each of the 12 capabilities, developing maturation plans and roadmaps for the identified performance gaps, specifying the interfaces between the various capabilities, and ensuring that the capabilities mature and integrate to enable future pioneering missions. By managing system development through the SMTs instead of traditional NASA programs and projects, the Agency is shifting from mission-driven development to a more flexible, capability-driven development. The process NASA uses to establish, integrate, prioritize, and manage the SMTs and associated capabilities is iterative. NASA relies on the Human Exploration and Operation Mission Directorate's SMT Integration Team within Advanced Exploration Systems to coordinate and facilitate the SMT process. The SMT Integration team conducts regular reviews and coordination meetings among the SMTs and has developed a number of tools to help the Agency implement capability driven processes. The SMT Integration team is uniquely positioned to help the Agency coordinate the SMTs and other processes that are making the capability-driven approach a reality. This paper will introduce the SMTs and the 12 key capabilities they represent. The role of the SMTs will be discussed with respect to Agency-wide processes to shift from mission-focused exploration to a capability-driven pioneering approach. Specific examples will be given to highlight systems development and testing within the SMTs. These examples will also show how NASA is using current investments in the International Space Station and future investments to develop and demonstrate capabilities. The paper will conclude by describing next steps and a process for soliciting feedback from the space exploration community to refine NASA's process for developing common exploration capabilities.

Williams-Byrd, Julie↗
NASA NTRS2016

Decision Analysis Methods Used to Make Appropriate Investments in Human Exploration Capabilities and Technologies

NASA is transforming human spaceflight. The Agency is shifting from an exploration-based program with human activities in low Earth orbit (LEO) and targeted robotic missions in deep space to a more sustainable and integrated pioneering approach. Through pioneering, NASA seeks to address national goals to develop the capacity for people to work, learn, operate, live, and thrive safely beyond Earth for extended periods of time. However, pioneering space involves daunting technical challenges of transportation, maintaining health, and enabling crew productivity for long durations in remote, hostile, and alien environments. Prudent investments in capability and technology developments, based on mission need, are critical for enabling a campaign of human exploration missions. There are a wide variety of capabilities and technologies that could enable these missions, so it is a major challenge for NASA's Human Exploration and Operations Mission Directorate (HEOMD) to make knowledgeable portfolio decisions. It is critical for this pioneering initiative that these investment decisions are informed with a prioritization process that is robust and defensible. It is NASA's role to invest in targeted technologies and capabilities that would enable exploration missions even though specific requirements have not been identified. To inform these investments decisions, NASA's HEOMD has supported a variety of analysis activities that prioritize capabilities and technologies. These activities are often based on input from subject matter experts within the NASA community who understand the technical challenges of enabling human exploration missions. This paper will review a variety of processes and methods that NASA has used to prioritize and rank capabilities and technologies applicable to human space exploration. The paper will show the similarities in the various processes and showcase instances were customer specified priorities force modifications to the process. Specifically, this paper will describe the processes that the NASA Langley Research Center (LaRC) Technology Assessment and Integration Team (TAIT) has used for several years and how those processes have been customized to meet customer needs while staying robust and defensible. This paper will show how HEOMD uses these analyses results to assist with making informed portfolio investment decisions. The paper will also highlight which human exploration capabilities and technologies typically rank high regardless of the specific design reference mission. The paper will conclude by describing future capability and technology ranking activities that will continue o leverage subject matter experts (SME) input while also incorporating more model-based analysis.

Williams-Byrd, Julie↗
NASA NTRS1998

Simple Automatic File Exchange (SAFE) to Support Low-Cost Spacecraft Operation via the Internet

Various issues associated with Simple Automatic File Exchange (SAFE) are presented in viewgraph form. Specific topics include: 1) Packet telemetry, Internet IP networks and cost reduction; 2) Basic functions and technical features of SAFE; 3) Project goals, including low-cost satellite transmission to data centers to be distributed via an Internet; 4) Operations with a replicated file protocol; 5) File exchange operation; 6) Ground stations as gateways; 7) Lessons learned from demonstrations and tests with SAFE; and 8) Feedback and future initiatives.

Baker, Paul↗
NASA NTRS2008

Best Practices for Researching and Documenting Lessons Learned

Identification, resolution, and avoidance of technical and programmatic issues are important for ensuring safe and successful space missions. Although the importance of applying lessons learned to reduce risk is frequently stressed, there is little material available to help technical and management personnel research and document lessons learned. Collecting, researching, identifying, and documenting lessons learned that will be useful to current and future management and engineering personnel is not always a straightforward task. This white paper presents lessons learned and best practices concerning the research and documentation of technical and organizational lessons learned. It is intended to enable organizations to initiate or improve lessons learned research and documentation efforts. The content of this white paper is based on four technical lessons learned projects conducted by the United Space Alliance (USA) Flight Design and Dynamics Department, in support of the NASA/Johnson Space Center (JSC) Flight Design and Dynamics Division. Each project published a report, titled as follows: (1) GPS Lessons Learned From the ISS, Space Shuttle and X-38; (2) Lessons Learned From Seven Space Shuttle Missions; (3) Space Shuttle Rendezvous and Proximity Operations Experience Report; and (4) Navigation Technical History with Lessons Learned. The four projects were different in availability of subject matter experts and primary source material, subject scope, and the level of effort required to produce the final report. However, generic lessons can be drawn from all of them. The best practices will be discussed by the phases of report research and development: (1) Defining Report Requirements, Project Organization, and Schedule; (2) Collection and Analysis of Source Material; (3) Writing and Integrating the Report; and (4) Review and Revision of the Report.

Goodman, John L.↗
NASA NTRS2009

Inflatable Habitat Health Monitoring: Implementation, Lessons Learned, and Application to Lunar or Martian Habitat Health Monitoring

NASA's exploration mission is to send humans to the Moon and Mars, in which the purpose is to learn how to live and work safely in those harsh environments. A critical aspect of living in an extreme environment is habitation, and within that habitation element there are key systems which monitor the habitation environment to provide a safe and comfortable living and working space for humans. Expandable habitats are one of the options currently being considered due to their potential mass and volume efficiencies. This paper discusses a joint project between the National Science Foundation (NSF), ILC Dover, and NASA in which an expandable habitat was deployed in the extreme environment of Antarctica to better understand the performance and operations over a one-year period. This project was conducted through the Innovative Partnership Program (IPP) where the NSF provided the location at McMurdo Station in Antarctica and support at the location, ILC Dover provided the inflatable habitat, and NASA provided the instrumentation and data system for monitoring the habitat. The outcome of this project provided lessons learned in the implementation of an inflatable habitat and the systems that support that habitat. These lessons learned will be used to improve current habitation capabilities and systems to meet the objectives of exploration missions to the moon and Mars.

Rojdev, Kristina↗