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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 37 records · Page 2
All sourcesNASA NTRSDOE OSTI
DOE OSTI2018

Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel

C-type inactivation is a time-dependent process observed in many K+ channels whereby prolonged activation by an external stimulus leads to a reduction in ionic conduction. While C-type inactivation is thought to be a result of a constriction of the selectivity filter, the local dynamics of the process remain elusive. Here, we use molecular dynamics (MD) simulations of the KcsA channel to elucidate the nature of kinetically delayed activation/inactivation gating coupling. Microsecond-scale MD simulations based on the truncated form of the KcsA channel (C-terminal domain deleted) provide a first glimpse of the onset of C-type inactivation. We observe over multiple trajectories that the selectivity filter consistently undergoes a spontaneous and rapid (within 1–2 µs) transition to a constricted conformation when the intracellular activation gate is fully open, but remains in the conductive conformation when the activation gate is closed or partially open. Multidimensional umbrella sampling potential of mean force calculations and nonequilibrium voltage-driven simulations further confirm these observations. Electrophysiological measurements show that the truncated form of the KcsA channel inactivates faster and greater than full-length KcsA, which is consistent with truncated KcsA opening to a greater degree because of the absence of the C-terminal domain restraint. Together, these results imply that the observed kinetics underlying activation/inactivation gating reflect a rapid conductive-to-constricted transition of the selectivity filter that is allosterically controlled by the slow opening of the intracellular gate.

Li, Jing↗
NASA NTRS2011

Optimized FPGA Implementation of Multi-Rate FIR Filters Through Thread Decomposition

Multi-rate finite impulse response (MRFIR) filters are among the essential signal-processing components in spaceborne instruments where finite impulse response filters are often used to minimize nonlinear group delay and finite precision effects. Cascaded (multistage) designs of MRFIR filters are further used for large rate change ratio in order to lower the required throughput, while simultaneously achieving comparable or better performance than single-stage designs. Traditional representation and implementation of MRFIR employ polyphase decomposition of the original filter structure, whose main purpose is to compute only the needed output at the lowest possible sampling rate. In this innovation, an alternative representation and implementation technique called TD-MRFIR (Thread Decomposition MRFIR) is presented. The basic idea is to decompose MRFIR into output computational threads, in contrast to a structural decomposition of the original filter as done in the polyphase decomposition. A naive implementation of a decimation filter consisting of a full FIR followed by a downsampling stage is very inefficient, as most of the computations performed by the FIR state are discarded through downsampling. In fact, only 1/M of the total computations are useful (M being the decimation factor). Polyphase decomposition provides an alternative view of decimation filters, where the downsampling occurs before the FIR stage, and the outputs are viewed as the sum of M sub-filters with length of N/M taps. Although this approach leads to more efficient filter designs, in general the implementation is not straightforward if the numbers of multipliers need to be minimized. In TD-MRFIR, each thread represents an instance of the finite convolution required to produce a single output of the MRFIR. The filter is thus viewed as a finite collection of concurrent threads. Each of the threads completes when a convolution result (filter output value) is computed, and activated when the first input of the convolution becomes available. Thus, the new threads get spawned at exactly the rate of N/M, where N is the total number of taps, and M is the decimation factor. Existing threads retire at the same rate of N/M. The implementation of an MRFIR is thus transformed into a problem to statically schedule the minimum number of multipliers such that all threads can be completed on time. Solving the static scheduling problem is rather straightforward if one examines the Thread Decomposition Diagram, which is a table-like diagram that has rows representing computation threads and columns representing time. The control logic of the MRFIR can be implemented using simple counters. Instead of decomposing MRFIRs into subfilters as suggested by polyphase decomposition, the thread decomposition diagrams transform the problem into a familiar one of static scheduling, which can be easily solved as the input rate is constant.

Kobayashi, Kayla N.↗
DOE OSTI2015

SU-C-207-06: In Vivo Quantification of Gold Nanoparticles Using K-Edge Imaging Via Spectrum Shaping by Gold Filter

Purpose: Gold nanoparticles (AuNP) are multifunctional platforms ideal for drug delivery, targeted imaging and radiosensitization. We have investigated quantitative imaging of AuNPs using on board imager (OBI) cone beam computed tomography (CBCT). To this end, we also present, for the first time, a novel method for k-edge imaging of AuNP by filter-based spectral shaping. Methods: We used a digital 25 cm diameter water phantom, embedded with 3 cm spheres filled with AuNPs of different concentrations (0 mg/ml – 16 mg/ml). A poly-energetic X-ray spectrum of 140 kVp from a conventional X-ray tube is shaped by balanced K-edge filters to create an excess of photons right above the K-edge of gold at 80.7 keV. The filters consist of gold, tin, copper and aluminum foils. The phantom with appropriately assigned attenuation coefficients is forward projected onto a detector for each energy bin and then integrated. FKD reconstruction is performed on the integrated projections. Scatter, detector efficiency and noise are included. Results: We found that subtracting the results of two filter sets (Filter A:127 µm gold foil with 254 µm tin, 330 µm copper and 1 mm aluminum, and Filter B: 635 µm tin with 264 µm copper and 1 mm aluminum), provides substantial image contrast. The resulting filtered spectra match well below 80.7 keV, while maintaining sufficient X-ray quanta just above that. Voxel intensities of AuNP containing spheres increase linearly with AuNP concentration. K-edge imaging provides 18% more sensitivity than the tin filter alone, and 38% more sensitivity than the gold filter alone. Conclusion: We have shown that it is feasible to quantitatively detect AuNP distributions in a patient-sized phantom using clinical CBCT and K-edge spectral shaping.

60 APPLIED LIFE SCIENCES↗
NASA NTRS1998

Multi-Bandwidth Frequency Selective Surfaces for Near Infrared Filtering: Design and Optimization

Frequency selective surfaces are widely used in the microwave and millimeter wave regions of the spectrum for filtering signals. They are used in telecommunication systems for multi-frequency operation or in instrument detectors for spectroscopy. The frequency selective surface operation depends on a periodic array of elements resonating at prescribed wavelengths producing a filter response. The size of the elements is on the order of half the electrical wavelength, and the array period is typically less than a wavelength for efficient operation. When operating in the optical region, diffraction gratings are used for filtering. In this regime the period of the grating may be several wavelengths producing multiple orders of light in reflection or transmission. In regions between these bands (specifically in the infrared band) frequency selective filters consisting of patterned metal layers fabricated using electron beam lithography are beginning to be developed. The operation is completely analogous to surfaces made in the microwave and millimeter wave region except for the choice of materials used and the fabrication process. In addition, the lithography process allows an arbitrary distribution of patterns corresponding to resonances at various wavelengths to be produced. The design of sub-millimeter filters follows the design methods used in the microwave region. Exacting modal matching, integral equation or finite element methods can be used for design. A major difference though is the introduction of material parameters and thicknesses that may not be important in longer wavelength designs. This paper describes the design of multi- bandwidth filters operating in the 1-5 micrometer wavelength range. This work follows on a previous design. In this paper extensions based on further optimization and an examination of the specific shape of the element in the periodic cell will be reported. Results from the design, manufacture and test of linear wedge filters built using microlithographic techniques and used in spectral imaging applications will be presented.

Cwik, Tom↗
NASA NTRS1999

Multi-Bandwidth Frequency Selective Surfaces for Near Infrared Filtering: Design and Optimization

Frequency selective surfaces are widely used in the microwave and millimeter wave regions of the spectrum for filtering signals. They are used in telecommunication systems for multi-frequency operation or in instrument detectors for spectroscopy. The frequency selective surface operation depends on a periodic array of elements resonating at prescribed wavelengths producing a filter response. The size of the elements is on the order of half the electrical wavelength, and the array period is typically less than a wavelength for efficient operation. When operating in the optical region, diffraction gratings are used for filtering. In this regime the period of the grating may be several wavelengths producing multiple orders of light in reflection or transmission. In regions between these bands (specifically in the infrared band) frequency selective filters consisting of patterned metal layers fabricated using electron beam lithography are beginning to be developed. The operation is completely analogous to surfaces made in the microwave and millimeter wave region except for the choice of materials used and the fabrication process. In addition, the lithography process allows an arbitrary distribution of patterns corresponding to resonances at various wavelengths to be produced. The design of sub-millimeter filters follows the design methods used in the microwave region. Exacting modal matching, integral equation or finite element methods can be used for design. A major difference though is the introduction of material parameters and thicknesses tha_ may not be important in longer wavelength designs. This paper describes the design of multi-bandwidth filters operating in the I-5 micrometer wavelength range. This work follows on previous design [1,2]. In this paper extensions based on further optimization and an examination of the specific shape of the element in the periodic cell will be reported. Results from the design, manufacture and test of linear wedge filters built using micro-lithographic techniques and used ir spectral imaging applications will be presented.

Cwik, Tom↗
NASA NTRS1974

A rocket borne instrument for the study of soft X-ray emission from cosmic X-ray sources

Details about a rocket-borne instrument designed for studying the various characteristics of soft X-ray emission from cosmic X-ray sources in the energy range of 0.2 to 3 keV are presented. The X-ray detector consists of a bank of four multilayer, wall-less proportional counters, each with an area of 400 sq cm. The detectors are covered by windows of 1.4-micron polypropylene and are maintained at a constant pressure in flight using a gas control system. Two of the detectors are equipped with 0.4- by 10-deg collimators for mapping the spatial distribution of soft X-rays from extended X-ray sources. A pair of balanced filters consisting of oxygen and CF4 are used for detecting oxygen emission lines.

Agrawal, P. C.↗
DOE OSTI2012

A PRECISION PHOTOMETRIC COMPARISON BETWEEN SDSS-II AND CSP TYPE Ia SUPERNOVA DATA

Consistency between Carnegie Supernova Project (CSP) and SDSS-II Supernova Survey ugri measurements has been evaluated by comparing Sloan Digital Sky Survey (SDSS) and CSP photometry for nine spectroscopically confirmed Type Ia supernova observed contemporaneously by both programs. The CSP data were transformed into the SDSS photometric system. Sources of systematic uncertainty have been identified, quantified, and shown to be at or below the 0.023 mag level in all bands. When all photometry for a given band is combined, we find average magnitude differences of equal to or less than 0.011 mag in ugri, with rms scatter ranging from 0.043 to 0.077 mag. The u-band agreement is promising, with the caveat that only four of the nine supernovae are well observed in u and these four exhibit an 0.038 mag supernova-to-supernova scatter in this filter.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2025

Mapping the gas density with the kinematic Sunyaev-Zel’dovich and patchy screening effects: A self-consistent comparison

The secondary anisotropies of the cosmic microwave background (CMB) provide a wealth of astrophysical and cosmological information. Pairing measurements of the CMB temperature map obtained by DR5 of the Atacama Cosmology Telescope (ACT) with the imaging survey conducted by the Dark Energy Spectroscopic Instrument for the purposes of target selection, DECaLS DR9, we investigate two effects that are sensitive to the gas density 𝜏: kinematic Sunyaev-Zel’dovich (kSZ) and patchy screening or anisotropic screening (resulting from the Thomson scattering of CMB photons away from the line-of-sight by free electrons). In particular, we measure the stacked profiles of the gas density around luminous red galaxies (LRGs) at a mean redshift of 𝑧 ≈ 0.7. We detect the kSZ signal at 7.2⁢𝜎, and we find a signal at ∼ 4.1⁢𝜎 for the patchy screening estimator, which is in excess relative to the kSZ signal. We attribute this excess to contamination from CMB lensing. Here, we demonstrate the effect of lensing using 𝑁-body simulations, and we show that the screening signal is dominated by it. Accounting for lensing, our measurement places a 95% upper bound on the optical depth of the Extended DESI LRG sample of 𝜏 < 2.5 10 −4 for a mean value of the sample of 𝜏 ≈ 1.6 10 −4 . Furthermore, via hydro simulations, we show that the underlying optical depth signal measured by both effects (after removing the CMB lensing contribution) is in perfect agreement when adopting either a compensated aperture photometry (CAP) filter or a high-pass filter. Consistent with previous measurements, we see evidence for excess baryonic feedback around DESI LRGs in the patchy screening measurement. In the future, when both effects can be measured with high signal-to-noise, one can measure the amplitude ratio between them, which is proportional to the root-mean-square velocity of the host halo sample, and even place constraints on velocity-sensitive models such as modified gravity and phantom dark energy.

Astrophysical & cosmological simulations↗
DOE OSTI2023

A common resequencing‐based genetic marker data set for global maize diversity

SUMMARY Maize ( Zea mays ssp. mays ) populations exhibit vast ranges of genetic and phenotypic diversity. As sequencing costs have declined, an increasing number of projects have sought to measure genetic differences between and within maize populations using whole‐genome resequencing strategies, identifying millions of segregating single‐nucleotide polymorphisms (SNPs) and insertions/deletions (InDels). Unlike older genotyping strategies like microarrays and genotyping by sequencing, resequencing should, in principle, frequently identify and score common genetic variants. However, in practice, different projects frequently employ different analytical pipelines, often employ different reference genome assemblies and consistently filter for minor allele frequency within the study population. This constrains the potential to reuse and remix data on genetic diversity generated from different projects to address new biological questions in new ways. Here, we employ resequencing data from 1276 previously published maize samples and 239 newly resequenced maize samples to generate a single unified marker set of approximately 366 million segregating variants and approximately 46 million high‐confidence variants scored across crop wild relatives, landraces as well as tropical and temperate lines from different breeding eras. We demonstrate that the new variant set provides increased power to identify known causal flowering‐time genes using previously published trait data sets, as well as the potential to track changes in the frequency of functionally distinct alleles across the global distribution of modern maize.

59 BASIC BIOLOGICAL SCIENCES↗
NASA NTRS1970

Improved photoionization mass spectrometer

Improved spectrometer for gas analysis lessens the intensity problem that occurs in obtaining dispersed ultraviolet radiation. A filter, consisting of a selectively transmitting gas cell, a thin film or mirror, or a predispersing grating, alleviates problems of interference from higher-order spectral lines and from scattered ultraviolet light.

Poshchenrieder, W. P.↗
NASA NTRS1979

Compact bypass-flow filter

Annular filter consisting of stacked rings separates particulates from bypass fluid passing through it in radial direction without slowing down main flow across unimpeded flow of fluid through its center. Applications include fluidized bed reactors, equipment for catalyst operations, and water purification.

Swift, W. G.↗
NASA NTRS1977

Failure detection and correction for turbofan engines

In this paper, a failure detection and correction strategy for turbofan engines is discussed. This strategy allows continuing control of the engines in the event of a sensor failure. An extended Kalman filter is used to provide the best estimate of the state of the engine based on currently available sensor outputs. Should a sensor failure occur the control is based on the best estimate rather than the sensor output. The extended Kalman filter consists of essentially two parts, a nonlinear model of the engine and up-date logic which causes the model to track the actual engine. Details on the model and up-date logic are presented. To allow implementation, approximations are made to the feedback gain matrix which result in a single feedback matrix which is suitable for use over the entire flight envelope. The effect of these approximations on stability and response is discussed. Results from a detailed nonlinear simulation indicate that good control can be maintained even under multiple failures.

Corley, R. C.↗
NASA NTRS1980

Scale effects: HCMM data simulation. Usage of filtering techniques for scaling-up simulations

Image reduction used to simulate increase in altitude of an acquisition platform is equivalent to data smoothing, and can be achieved either by neighborhood averaging or by filtering techniques. The averaging approach is limited for accurate simulation. A filtering method is described which was based on the hypothesis that all changes due to altitude increase can be represented by a point spread function. Determination of the scale function and factor are discussed as well as implementation of the filtering. Filtering can be either in the spatial or frequency domain. In the spatial domain, filtering consists of the convolution of the image with the weights mask, and then of the declination of the points according to the appropriates scale factor. A simulation of an aircraft day image in the infrared channel is examined.

Digennaro, V.↗
NASA NTRS1991

Adaptive filtering and maximum entropy spectra with application to changes in atmospheric angular momentum

The spectral resolution and statistical significance of a harmonic analysis obtained by low-order MEM can be improved by subjecting the data to an adaptive filter. This adaptive filter consists of projecting the data onto the leading temporal empirical orthogonal functions obtained from singular spectrum analysis (SSA). The combined SSA-MEM method is applied both to a synthetic time series and a time series of AAM data. The procedure is very effective when the background noise is white and less so when the background noise is red. The latter case obtains in the AAM data. Nevertheless, reliable evidence for intraseasonal and interannual oscillations in AAM is detected. The interannual periods include a quasi-biennial one and an LF one, of 5 years, both related to the El Nino/Southern Oscillation. In the intraseasonal band, separate oscillations of about 48.5 and 51 days are ascertained.

Penland, Cecile↗
NASA NTRS1997

Miniaturized High-Temperature Superconducting/Dielectric Multilayer Filters for Satellite Communications

Most communication satellites contain well over a hundred filters in their payload. Current technology in typical satellite multiplexers use dual-mode cavity or dielectric resonator filters that are large (approx. 25 to 125 cu in) and heavy (up to 600 g). As the complexity of future advanced electronic systems for satellite communications increases, even more filters will be needed, requiring filter miniaturization without performance degradation. Such improvements in filter technology will enhance satellite performance. To reduce the size, weight, and cost of the multiplexers without compromising performance, the NASA Lewis Research Center is collaborating with industry to develop a new class of dual-mode multilayer filters consisting of YBa2Cu3O7-delta high-temperature superconducting (HTS) thin films on LaAlO3 substrates.

Miranda, Felix A.↗
NASA NTRS2004

Rotating Reverse-Osmosis for Water Purification

A new design for a water-filtering device combines rotating filtration with reverse osmosis to create a rotating reverse- osmosis system. Rotating filtration has been used for separating plasma from whole blood, while reverse osmosis has been used in purification of water and in some chemical processes. Reverse- osmosis membranes are vulnerable to concentration polarization a type of fouling in which the chemicals meant not to pass through the reverse-osmosis membranes accumulate very near the surfaces of the membranes. The combination of rotating filtration and reverse osmosis is intended to prevent concentration polarization and thereby increase the desired flux of filtered water while decreasing the likelihood of passage of undesired chemical species through the filter. Devices based on this concept could be useful in a variety of commercial applications, including purification and desalination of drinking water, purification of pharmaceutical process water, treatment of household and industrial wastewater, and treatment of industrial process water. A rotating filter consists of a cylindrical porous microfilter rotating within a stationary concentric cylindrical outer shell (see figure). The aqueous suspension enters one end of the annulus between the inner and outer cylinders. Filtrate passes through the rotating cylindrical microfilter and is removed via a hollow shaft. The concentrated suspension is removed at the end of the annulus opposite the end where the suspension entered.

Lueptow, RIchard M.↗
NASA NTRS2004

Combining Particle Filters and Consistency-Based Approaches for Monitoring and Diagnosis of Stochastic Hybrid Systems

Fault detection and isolation are critical tasks to ensure correct operation of systems. When we consider stochastic hybrid systems, diagnosis algorithms need to track both the discrete mode and the continuous state of the system in the presence of noise. Deterministic techniques like Livingstone cannot deal with the stochasticity in the system and models. Conversely Bayesian belief update techniques such as particle filters may require many computational resources to get a good approximation of the true belief state. In this paper we propose a fault detection and isolation architecture for stochastic hybrid systems that combines look-ahead Rao-Blackwellized Particle Filters (RBPF) with the Livingstone 3 (L3) diagnosis engine. In this approach RBPF is used to track the nominal behavior, a novel n-step prediction scheme is used for fault detection and L3 is used to generate a set of candidates that are consistent with the discrepant observations which then continue to be tracked by the RBPF scheme.

Narasimhan, Sriram↗