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Selection of Next Priority IMPACT Medical Conditions Based on Available Terrestrial and Spaceflight Data

BACKGROUND: As the era of exploration class missions begins, identification of medical conditions that may occur and require management becomes essential for the modeling of medical risk. To this end, NASA has developed IMPACT (Informing Mission Planning via Analysis of Complex Tradespaces), a suite of tools to assist in assessment of medical risk analysis. It has incorporated an initial list of the 120 conditions of highest concern, labeled the IMPACT condition list 1.0 (ICL 1.0). This abstract describes a method for prioritizing the 92 conditions included on the Proposed Future Conditions List (PFCL) for inclusion in future iterations of the ICL. OVERVIEW: To construct the Prioritized Proposed Future Conditions List (P-PFCL), each condition on the PFCL was scored as “low,” “medium,” or “high” on each of four variables: incidence, likelihood of significant task impairment, diagnostic and treatment complexity, and treatment futility. Qualitative assessment using clinical judgement was utilized to score complexity, futility, and likelihood of impairment. Incidence was assessed quantitatively using spaceflight data and/or analog populations where available then assigned a score using established cutoffs. Logarithmic numerical values were assigned to each category label. A Prioritization Score was generated for each condition by taking the product of incidence and likelihood of task impairment (risk) divided by the product of complexity and futility (difficulty of care), with higher values corresponding to higher priority for future inclusion in the ICL. DISCUSSION: The described methods allow for the generation of a ranked P-PFCL to act as a decision support tool for selection of the next generation of modeled medical conditions. Some of the conditions ranked highly on the P-PFCL include EVA-related upper and lower extremity sprain/strain, iron deficiency, delirium, and hypertension, among others. While this effort does not attempt to quantify the absolute risk associated with each condition, it does attempt to semi-quantitatively estimate the risk of each condition relative to the other possible conditions. This tool in concert with subject matter expert opinion could optimize the future use of limited resources thereby producing a more accurate medical risk model, which will be essential to the upcoming exploration class missions.

Michael Pohlen

Relevant Environment Additive Construction Technology (REACT)

Project Overview This project is focused on developing technologies that enable construction of a Lunar Safe Haven type structure on the moon. A full scale architectural and structural design will be completed based on lunar conditions and Artemis mission needs. A scaled structure will be 3D printed in simulated lunar environments. Technical Approach Polymer bound regolith composite materials will be developed and characterized for lunar additive construction applications. A full scale architectural and structural design will be completed based on the latest scientific data on lunar environments including radiation, meteoroids, thermal conditions, reduced gravity, and moonquakes. The project will culminate with a demonstration of additive construction in simulated lunar vacuum, thermal, regolith, and UV conditions. Results/Summary Preliminary material specifications have been developed and an initial batch has been produced. A first iteration of the architectural and structural designs have been completed. Hardware for 3D printing in simulated lunar conditions is under development. Contributing Partners AI Space Factory – Winner of the NASA 3D Printed Habitat Centennial Challenge Infusion and Transition Plan On-surface construction of infrastructure is a critical capability of the sustainable phase of the Artemis Program and eventual sustainable human presence on Mars. It provides the ability to create protective shelters on-demand using local resources. The 3D-printing technology will achieve TRL 6 in 1g/vacuum tests with thermal/UV exposure in this project. CLPS missions will be pursued for infusion to demonstrate vertical construction with lunar regolith and conditions. Modeling and simulation will be used to define the pilot-scale shelter construction mission for long-term exposure on the lunar surface to validate the system for Artemis operational deployment.

Lunar Construction

MICROREACTOR APPLICATIONS, RESEARCH, VALIDATION, AND EVALUATION (MARVEL) REACTOR ? STATUS, CONSTRUCTION, AND TESTING

The paper presents the current status of the Microreactor Applications, Research, Validation, and Evaluation (MARVEL) microreactor design, qualification testing, fabrication, and high-level construction schedule. An overview of initial criticality, low power physics testing, and start-up testing is included, as well as an overview of the envisioned processes in which end-users can engage the project for access to operational data or specific demonstrations. Designed by the Idaho National Laboratory (INL) under the auspices of the US Department of Energy’s Microreactor Program for construction and operation at the INL, MARVEL is a small, fully functional advanced reactor with UZrH fuel and thermal output of 85 kW. It offers a unique opportunity for scaled demonstrations that can dramatically accelerate the design, licensing, and deployment of commercial microreactors for power production or process heat applications. MARVEL’s objective is to build a small liquid-metal thermal reactor at the INL to demonstrate design and operating processes for microreactors, microgrid integration, and process heat applications. MARVEL finished 90%-final-design in September 2023 and completed an independent project assessment in early 2024. Fabrication of long-lead components and fuel, safety analysis review, and procurement for construction are underway. MARVEL assembly and construction will start in 2025 and fuel loading is expected in mid- 2027. Initial criticality will be performed in a dry condition in late 2027, followed by loading of NaK coolant and start-up testing. Approximately six months later, release for unrestricted operations will enable subsequent testing of microreactor characteristics, microgrid integration and select heat extraction applications.

22 GENERAL STUDIES OF NUCLEAR REACTORS

Lessons Learned from the Construction of Upgrades to the NASA Glenn Icing Research Tunnel and Re-activation Testing

Major upgrades were made in 1999 to the 6- by 9-Foot (1.8- by 2.7-m) Icing Research Tunnel (IRT) at the NASA Glenn Research Center. These included replacement of the electronic controls for the variable-speed drive motor, replacement of the heat exchanger, complete replacement and enlargement of the leg of the tunnel containing the new heat-exchanger, the addition of flow-expanding and flow-contracting turning vanes upstream and downstream of the heat exchanger, respectively, and the addition of fan outlet guide vanes (OGV's). This paper presents an overview of the construction and reactivation testing phases of the project. Important lessons learned during the technical and contract management work are documented.

Sheldon, David W.

High-resolution detectors for imaging and spectroscopy at ultraviolet and soft X-ray wavelengths

The Multi-Anode Microchannel Arrays (MAMAs) are a family of pulse-counting imaging array detectors designed specifically for astrophysical investigations in space. The MAMAs have a number of unique performance characteristics which make them particularly suitable for imaging and spectroscopy at ultraviolet and soft X-ray wavelengths. First, they employ 'solar blind' photocathodes eliminating the 'red leak' problem associated with solid state arrays such as the CCDs. Second, they operate with zero readout noise, yielding photon-statistics limited signals. Third, they utilize a random readout technique and can determine both the location of a detected photon and also its arrival time to an accuracy of the order of 100 ns. This paper gives an overview of the construction, mode of operation, and performance characteristics of the MAMA detectors and describes the current status of the development program.

Timothy, J. G.

International Space Station Video Progress Report

A narrated overview of the construction and assembly of the International Space Station (ISS) is given through a collection of clips ranging from the launch of the Russian Proton rocket containing the Zvezda module to computerized animations showing the installation of the Zarya and Unity connecting modules. Footage from some of the space missions that assembled the ISS in space (i.e., STS-106 and STS-92) are seen. The Z1 truss (including the deployment of the solar arrays), Destiny Laboratory Module, Leonardo Module, the Japanese Kibo Experiment Module, Columbus Pressurized Module, and the ISS's robotic arm are seen. Animations show the assembly and evolution of the ISS as new components are added.

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Large space structures - Structural concepts and materials

Large space structures will be a key element of the future space activities. They will include spacecraft such as the planned Space Station and large antenna/reflector structures for communications and observations. These large structures will exceed 100 m in length or 30 m in diameter. Concepts for construction of these spacecraft on orbit and their materials of construction provide some unique research challenges. This paper will provide an overview of the research in space construction of large structures including erectable and deployable concepts. Also, an approach to automated, on-orbit construction will be presented. Materials research for space applications focuses on high stiffness, low expansion composite materials that provide adequate durability in the space environment. The status of these materials research activities will be discussed.

Blankenship, Charles P.

Microwave Sintering for Lunar Base Construction

Presentation to the Materials Science and Technology Conference 2023 on microwave sintering for the construction of a lunar base. Content includes an overview of NASA's goals, lunar materials, lunar construction, development and testing of the microwave sintered materials, and a summary of the work to date.

Microwave sintering

Strong Thermoset Regolith UV-Curable Composite Technology (STRUCT) Overview

Future lunar surface missions require construction materials that can be manufactured in situ using lo-cal resources while operating under extreme environmental conditions. Many Lunar material demands can be solved solely with regolith by compacting or sintering. And yet past Lunar missions rely on polymeric materials, and sustained Lunar missions must reduce Earth-supplied polymers dependence. Dual-cure (Ultraviolet (UV) and thermal) polymer-regolith composites offer a promising pathway by leveraging solar UV radiation, moderate thermal in-put, and regolith. Mission mass limits, power availability and energy constraints on the lunar surface further motivate low-energy processing and curing strategies for surface construction materials. The Strong Thermoset Regolith UV-Curable Composite Technology (STRUCT) project has successfully synthesized and demonstrated dual-cure photopolymer resins derivable from in-situ resources [3]. Morphological, thermal, and mechanical characterization show that the newly formulated UV curable resin systems integrates well with lunar regolith simulants. Processing and chemistry changes, and computational analysis advanced the composite design. X-ray CT scanned and computational analysis demonstrate that resin, regolith and additives are well incorporated. The large fraction of regolith, 95% by mass, large char yield (82% mass), low thermal conductivity (0.26 W/m/K), confirm this material as a promising high-performance thermal and structural material.

thermal conductivity

Capabilities, Design, Construction and Commissioning of New Vibration, Acoustic, and Electromagnetic Capabilities Added to the World's Largest Thermal Vacuum Chamber at NASA's Space Power Facility

NASA s human space exploration plans developed under the Exploration System Architecture Studies in 2005 included a Crew Exploration Vehicle launched on an Ares I launch vehicle. The mass of the Crew Exploration Vehicle and trajectory of the Ares I coupled with the need to be able to abort across a large percentage of the trajectory generated unprecedented testing requirements. A future lunar lander added to projected test requirements. In 2006, the basic test plan for Orion was developed. It included several types of environment tests typical of spacecraft development programs. These included thermal-vacuum, electromagnetic interference, mechanical vibration, and acoustic tests. Because of the size of the vehicle and unprecedented acoustics, NASA conducted an extensive assessment of options for testing, and as result, chose to augment the Space Power Facility at NASA Plum Brook Station, of the John H. Glenn Research Center to provide the needed test capabilities. The augmentation included designing and building the World s highest mass capable vibration table, the highest power large acoustic chamber, and adaptation of the existing World s largest thermal vacuum chamber as a reverberant electromagnetic interference test chamber. These augmentations were accomplished from 2007 through early 2011. Acceptance testing began in Spring 2011 and will be completed in the Fall of 2011. This paper provides an overview of the capabilities, design, construction and acceptance of this extraordinary facility.

Motil, Susan M.

Critical Technologies for the Development of Future Space Elevator Systems

A space elevator is a tether structure extending through geosynchronous earth orbit (GEO) to the surface of the earth. Its center of mass is in GEO such that it orbits the earth in sync with the earth s rotation. In 2004 and 2005, the NASA Marshall Space Flight Center and the Institute for Scientific Research, Inc. worked under a cooperative agreement to research the feasibility of space elevator systems, and to advance the critical technologies required for the future development of space elevators for earth to orbit transportation. The discovery of carbon nanotubes in the early 1990's was the first indication that it might be possible to develop materials strong enough to make space elevator construction feasible. This report presents an overview of some of the latest NASA sponsored research on space elevator design, and the systems and materials that will be required to make space elevator construction possible. In conclusion, the most critical technology for earth-based space elevators is the successful development of ultra high strength carbon nanotube reinforced composites for ribbon construction in the 1OOGPa range. In addition, many intermediate technology goals and demonstration missions for the space elevator can provide significant advancements to other spaceflight and terrestrial applications.

Smitherman, David V., Jr.

PASS: A computer program for Preliminary Aircraft Structural Synthesis

A computer code for Preliminary Aircraft Structural Synthesis provides rapid and accurate analysis for aircraft structures that can be adequately modeled by beam finite elements. The philosophy used in developing the program was to provide a basic framework that can be used for structural synthesis. It is anticipated that a user will need to add detail to this framework in order to perform his specific task. With this philosophy in mind, the program was written so that it is easily divided into segments, thereby making it readily adaptable. The theoretical portion of this manual describes the basic structure of the program and details the development of the unique beam element that is used. The present capability of the algorithm is stated and suggestions are made regarding enhancements to this capability. User information is also given that provides an overview of the program's construction, identifies the required inputs, describes the program output, provides some comments on the program use, and exhibits results for a simple example.

Johnson, E. H.

Designing Space Station

An overview of preparations for the construction of Space Station Freedom (SSF) is presented. The video includes footage of astronauts testing materials for erectable structures in space both in the Shuttle bay while in orbit and in a neutral buoyancy tank at McDonald Douglas' Underwater Test Facility. Also shown are footage of robot systems that will assist the astronauts in building SSF, a computer simulation of an Orbiting Maneuvering Vehicle, solar dynamic mirrors that will power SSF, and mockups of the living quarters of the SSF.

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