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Variational autoencoders for at-source data reduction and anomaly detection in high energy particle detectors

Detectors in next-generation high-energy physics experiments face several daunting requirements, such as high data rates, damaging radiation exposure, and stringent constraints on power, space, and latency. To address these challenges, machine learning in readout electronics can be leveraged for smart detector designs, enabling intelligent inference and data reduction at-source. Variational autoencoders (VAEs) offer a variety of benefits for front-end readout; an on-sensor encoder can perform efficient lossy data compression while simultaneously providing a latent space representation that can be used for anomaly detection. Results are presented from low-latency and resource-efficient VAEs for front-end data processing in a futuristic silicon pixel detector. Encoder-based data compression is found to preserve good performance of off-detector analysis while significantly reducing the off-detector data rate as compared to a similarly sized data filtering approach. Furthermore, the latent space information is found to be a useful discriminator in the context of real-time sensor defect monitoring. Together, these results highlight the multifaceted utility of autoencoder-based front-end readout schemes and motivate their consideration in future detector designs.

47 OTHER INSTRUMENTATION↗

SAMPA Based Streaming Readout Data Acquisition Prototype

We have assembled a small-scale streaming data acquisition system based on the SAMPA front-end ASIC. The 32-channel SAMPA chip was designed for the high-luminosity upgrade of the ALICE Time Projection Chamber (TPC) detector at the CERN Large Hadron Collider. The goals of the prototype system are to determine if the SAMPA chip is appropriate for use in detector systems at Jefferson Lab, and to gain experience with the hardware and software required to deploy streaming data acquisition systems in nuclear physics experiments. The 800 channel system is composed of components used in the ALICE TPC data acquisition upgrade. Five front-end cards (FEC) support five SAMPA chips each. SAMPA data streams on an FEC are concentrated into two high-speed (4.48 Gb/s) serial data streams by a pair Gigabit Transceiver ASICs (GBTx). These ten streams (44.8 Gb/s) are transmitted from the FECs over fibers to a PCIe based readout unit. The FPGA engine on the readout unit compresses data for transmission to a server via 100 Gb ethernet. Components on the FECs are radiation tolerant. High data rates can be handled. The system is by design scalable and thus provides a functional prototype for high-rate streaming readout at Jefferson Lab and the future Electron Ion Collider. We have made fundamental measurements (noise, linearity, time resolution) on the SAMPA ASIC. We have also coupled the readout system to a small Gas Electron Multiplier (GEM) detector and have studied its response to cosmic rays. A beam test of the system is planned.

ABBOTT, David↗

Transformative Technology for FLASH Radiation Therapy

The general concept of radiation therapy used in conventional cancer treatment is to increase the therapeutic index by creating a physical dose differential between tumors and normal tissues through precision dose targeting, image guidance, and radiation beams that deliver a radiation dose with high conformality, e.g., protons and ions. However, the treatment and cure are still limited by normal tissue radiation toxicity, with the corresponding side effects. A fundamentally different paradigm for increasing the therapeutic index of radiation therapy has emerged recently, supported by preclinical research, and based on the FLASH radiation effect. FLASH radiation therapy (FLASH-RT) is an ultra-high-dose-rate delivery of a therapeutic radiation dose within a fraction of a second. Experimental studies have shown that normal tissues seem to be universally spared at these high dose rates, whereas tumors are not. While dose delivery conditions to achieve a FLASH effect are not yet fully characterized, it is currently estimated that doses delivered in less than 200 ms produce normal-tissue-sparing effects, yet effectively kill tumor cells. Despite a great opportunity, there are many technical challenges for the accelerator community to create the required dose rates with novel compact accelerators to ensure the safe delivery of FLASH radiation beams.

43 PARTICLE ACCELERATORS↗

Impact of biomass burning aerosols on radiation, clouds, and precipitation over the Amazon: relative importance of aerosol–cloud and aerosol–radiation interactions

Biomass burning (BB) aerosols can influence regional and global climate through interactions with radiation, clouds, and precipitation. Here, we investigate the impact of BB aerosols on the energy balance and hydrological cycle over the Amazon Basin during the dry season. We performed simulations with a fully coupled meteorology–chemistry model, the Weather Research and Forecasting model coupled with Chemistry (WRF-Chem), for a range of different BB emission scenarios to explore and characterize nonlinear effects and individual contributions from aerosol–radiation interactions (ARIs) and aerosol–cloud interactions (ACIs). The ARIs of BB aerosols tend to suppress low-level liquid clouds by local warming and increased evaporation and to facilitate the formation of high-level ice clouds by enhancing updrafts and condensation at high altitudes. In contrast, the ACIs of BB aerosol particles tend to enhance the formation and lifetime of low-level liquid clouds by providing more cloud condensation nuclei (CCN) and to suppress the formation of high-level ice clouds by reducing updrafts and condensable water vapor at high altitudes (>8 km). For scenarios representing the lower and upper limits of BB emission estimates for recent years (2002–2016), we obtained total regional BB aerosol radiative forcings of –0.2 and 1.5 W m –2 , respectively, showing that the influence of BB aerosols on the regional energy balance can range from modest cooling to strong warming. We find that ACIs dominate at low BB emission rates and low aerosol optical depth (AOD), leading to an increased cloud liquid water path (LWP) and negative radiative forcing, whereas ARIs dominate at high BB emission rates and high AOD, leading to a reduction of LWP and positive radiative forcing. In all scenarios, BB aerosols led to a decrease in the frequency of occurrence and rate of precipitation, caused primarily by ACI effects at low aerosol loading and by ARI effects at high aerosol loading. The dependence of precipitation reduction on BB aerosol loading is greater in a strong convective regime than under weakly convective conditions. Overall, our results show that ACIs tend to saturate at high aerosol loading, whereas the strength of ARIs continues to increase and plays a more important role in highly polluted episodes and regions. This should hold not only for BB aerosols over the Amazon, but also for other light-absorbing aerosols such as fossil fuel combustion aerosols in industrialized and densely populated areas. The importance of ARIs at high aerosol loading highlights the need for accurately characterizing aerosol optical properties in the investigation of aerosol effects on clouds, precipitation, and climate.

54 ENVIRONMENTAL SCIENCES↗

Transformative Technology for FLASH Radiation Therapy: A Snowmass 2021 White Paper

Conventional cancer therapies include surgery, radiation therapy, chemotherapy, and, more recently, immunotherapy. These modalities are often combined to improve the therapeutic index. The general concept of radiation therapy is to increase the therapeutic index by creating a physical dose differential between tumors and normal tissues through precision dose targeting, image guidance, and high radiation beams that deliver radiation dose with high conformality, e.g., protons and ions. However, treatment and cure are still limited by normal tissue radiation toxicity, with many patients experiencing acute and long-term side effects. Recently, however, a fundamentally different paradigm for increasing the therapeutic index of radiation therapy has emerged, supported by preclinical research, and based on the FLASH radiation effect. FLASH radiation therapy (FLASH-RT) is an ultra-high dose-rate delivery of a therapeutic radiation dose within a fraction of a second. Experimental studies have shown that normal tissues seem to be universally spared at these high dose rates, whereas tumors are not. The dose delivery conditions are not yet fully characterized. Still, it is currently estimated that large doses of 10 Gy or more delivered in 200 ms or less produce normal tissue sparing effects yet effectively kill tumor cells. There is a great opportunity, but also many technical challenges, for the accelerator community to create the required dose rates with novel and compact accelerators to ensure the safe delivery of FLASH radiation beams.

43 PARTICLE ACCELERATORS↗

Radiation Testing for High-Resolution Radiation-Hardened Camera System (Final CRADA Report)

The nuclear energy industry needs higher-image quality and higher rad-hard vision systems for refueling and inspection operations that are required every 12-18 months for all operating commercial reactors. During refueling operations, the serial numbers of fuel assemblies need to be visually verified in a challenging high radiation environment with dose rates on the order of 1kGy/hr. at the top of the core (approximately 10 days after shutdown). Vega Wave Systems has developed and built a radiation hard vision system that: 1. has high radiation hardness, 2. demonstrated best in the industry image quality, 3. has small size and weight, and 4. does not suffer from radiation-induced noise. ANL-1060 (02/13/2023) The proprietary Enduray vision system from Vega Wave Systems, Inc. is designed to withstand more than 400x the radiation level of the Vidicon-based systems, currently the highest radiation tolerant system in use today. The Van De Graaff (VDG) electron accelerator at Argonne National Laboratory is ideally suited for testing of Enduray vision system. VDG provides a broad band (up to 3 MeV) x-ray source that reasonably approximates the energy and spectrum of the gamma radiation expected at the top of a nuclear core 10 days after shutdown (~1kGy/hr.), is easily controlled for variable tests, and will not activate the parts under radiation for ease of timely and close inspection and characterization of the system in case of operational issues.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Single-particle dynamics of microbunching

The mechanism of steady-state microbunching (SSMB) has been proposed [D. F. Ratner and A. W. Chao, Phys. Rev. Lett. 105, 154801 (2010)] to generate high-power coherent radiation at a high repetition rate or in continuous-wave mode using electron storage rings. In this paper, the related single-particle dynamics are theoretically and numerically studied, and important results are presented. The investigated effects are longitudinal quantum radiation excitation, nonlinear momentum compaction, and linear and nonlinear coupling of the transverse and longitudinal motion. Although this analysis is oriented toward SSMB, some of the analyzed effects are also crucial in cases such as coherent harmonic generation, bunch slicing, bunch compression, free-electron laser beam transport lines, and quasi-isochronous rings, which involve precise longitudinal phase-space manipulations.

43 PARTICLE ACCELERATORS↗

X-Ray Spectra from General Relativistic Radiation Magnetohydrodynamic Simulations of Thin Disks

We compare X-ray emission from several general relativistic, multifrequency, radiation magnetohydrodynamic simulations of thin black hole accretion disks with different accretion rates and spins. The simulations were performed using the M1 closure scheme, resolved with 12 frequency (energy) bins logarithmically spaced from 5 × 10 −3 to 5 × 10 3 ​​​ keV. We apply a general relativistic Monte Carlo transport code to postprocess the simulation data with greater fidelity in frequency resolution and Compton scattering treatment. Despite the relatively few energy bins and Kompaneets approximation to Compton scattering utilized in the M1 method, we find generally good agreement between the methods. Both produce prominent thermal profiles with peaks around 2–2.5 keV, where agreement is particularly strong and representative of the soft state. Both also find weaker (lower-luminosity) thermally sourced emission extending out to 100 keV due to the hotter innermost regions of the disks. Inverse Compton scattering becomes increasingly effective at hardening spectral outputs with increasing black hole spin, and becomes the dominant mechanism for photons that escape with energies between 10 to several hundred keV. At very high rates of spin, the radiation flux in this upscattered component becomes comparable to the thermal flux, a phenomenon typically associated with intermediate states. Beyond 10 4 keV, we observe faint, free–free emission from hot, optically thin coronal regions developing near the horizon, common to both spinning and nonspinning black holes.

79 ASTRONOMY AND ASTROPHYSICS↗

NDX: Neutron Dose Rate Meters with Extended Capabilities

Particle accelerators, irradiation facilities, and nuclear power plants would benefit from using neutron dose rate meters featuring improved energy response covering full range of expected neutron energies, improved dynamic range of measured dose rates while providing the real-time data, and improved ability to operate in harsh radiation environments including heavy photon backgrounds and pulsed beams. The novel design of the neutron moderator for the NDX dose rate meter implements a layer of a Beryllium-loaded medium Z material which, similar to the earlier known WENDI detectors, allows the device to detect higher energy neutron flux and convert it to dose. Using Beryllium helps to fill the known dip in the response functions around 5-50 MeV. Optimized design parameter set, obtained using FLUKA Monte Carlo simulations, features the NDX moderator made of polyethylene embedding a layer of BeCu alloy inside, with the dose rate response constant within ±10% in the neutron energy range from about 100 keV to 500 MeV, and ±25% essentially in the full energy range above thermal. A new sensor technique implemented in the NDX is based on using the Ionization Chamber (IC) filled with 3He gas to capture the moderated neutron fluence, and includes a symmetric IC filled with regular 4He to evaluate the contributions due to the non-neutron ionizing radiation. Advantages of the method include large accessible dynamic range, relative insensitivity of the IC probes to photon radiation fields, and the ability to subtract their contribution. Two prototype NDX detectors were built, calibrated, and operated in various conditions at the CEBAF 12 GeV electron accelerator at JLab. The first results showed reliable neutron dose rate measurements in the presence of overwhelming photon radiation fields, and at practical high dose rate levels of up to approximately 10 Sv/h. Detector design, operation, first results, and further development plans are presented.

Degtiarenko, Pavel V.↗

CAAS-3S Radiation Testing for Y-12 and UPF with Godiva-IV

The Y-12 National Security Complex and the Uranium Processing Facility (UPF) selected the Mirion CAAS-3S as the Criticality Accident Alarm System for UPF and for Y-12 facilities replacing their legacy CAAS as part of efforts to extend the facility lifespans. As part of this process, the CAAS-3S system was exposed to a high radiation dose and dose rate during reactor testing with the Godiva-IV fast burst reactor. The reactor testing was designed around preliminary analyses that determined Y-12 and UPF requirements, and simulations of the radiation field within the reactor facility were used to determine reactor operating parameters, CAAS equipment locations, and the design of a neutron shield wall. This paper presents the design and results of the testing, and discusses how the test results were interpreted by criticality safety engineers at Y-12 and UPF.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Investigating the FLASH Effect in a Rat Brain Organotypic Model With a Novel High-Energy Electron Beam

Ultrahigh dose rate (FLASH) radiation therapy is reported to reduce normal tissue toxicity while maintaining tumor control; however, mechanism(s) remain obscure. To study FLASH mechanisms in brain tissue, we developed a novel experimental platform featuring a specialized high-energy electron linear accelerator, High Intensity Gamma Ray Source (HIGS), paired with an organotypic ex vivo brain metastasis model. We varied interpulse spacing to modulate the mean dose rate (MDR) of our unique 35 MeV electron beam, while maintaining extremely high instantaneous dose rate (IDR). We characterized dosimetry and targeting accuracy of the FLASH beam with film dosimetry. We combined this FLASH beam with an organotypic rat brain slice/breast carcinoma coculture model of brain metastasis to assess effects on normal and neoplastic tissues. Live-cell and bioluminescence imaging demonstrated cancer cell growth effects, whereas normal tissue responses and immune activation were assessed using live-cell imaging, cytokine profiles, and confocal microscopy. Here, we performed comparison experiments with 20 MeV electrons from a Varian clinical linear accelerator (VCLA) using conventional dose rates. The highest IDR of the FLASH beam to date was 20.7 ± 0.6 MGy/s, with maximum MDR of 20.7 MGy/s delivered in 1 pulse of 1 µs duration. Beam targeting was accurate to <1 mm and reproducible. HIGS-FLASH and VCLA dose rates equivalently decreased cancer cell growth. HIGS-FLASH irradiation significantly increased tumor necrosis factor α and fractalkine levels and confocal microscopy revealed distinct changes in microglial morphology slices suggesting microglia activation. Our novel experimental platform produces extremely high dose rates and rapid normal/neoplastic tissue readouts for mechanistic research into the effects of FLASH radiation in the brain. HIGS-FLASH irradiation induces comparable cancer cell growth inhibition but differential effects on cytokines and microglial morphology, suggesting that acute innate immune responses may be involved in FLASH normal tissue effects in the brain.

Kay, Tyler V. [Duke University, Durham, NC (United↗

Subthreshold Erosion of an Organic Polymer Induced by Multiple Shots of an X-Ray Free-Electron Laser

We report solids irradiated by energetic photons can be eroded in two modes, depending on the radiation intensity. High average, low-peak power sources, e.g., synchrotron radiation and high-order harmonics, induce desorption of the material at a low etch rate. In contrast, high-peak-power radiation from extreme ultraviolet and x-ray lasers usually causes a massive removal of the material even by a single shot. In this contribution, an effective material erosion is reported in PMMA exposed to multiple accumulated pulses generated by the free-electron x-ray-laser Linac Coherent Light Source (LCLS, tuned at a photon energy of 830 eV in this study, operated in Menlo Park at Stanford, CA, USA) at a fluence below the single-pulse ablation threshold. The effect is caused by polymer-chain scissions initiated by single photons carrying enough energy to break the C—C bounds. High efficiency of the erosion is supposed to occur due to a correlation of the single-photon effects. The subthreshold damage exhibits a nonlinear dose dependence resulting from a competition between chain scissions and cross-linking processes. The cross-linking is proven by Raman spectroscopy of the irradiated polymer. Two theoretical models of the x-ray free-electron-laser-induced erosion are suggested, which provide an excellent agreement with the experimental results.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Electronics for the far-forward CMS muon detector upgrade, ME0

Abstract With the High Luminosity upgrade of the Large Hadron Collider (LHC) we expect increased instantaneous luminosities up to 7.5 × 10 34 cm −2 s −1 , or five times more than the original values. In order to maintain performance of the Compact Muon Solenoid (CMS) experiment under these conditions, ME0 is one of three new muon sub-detectors being added, along with GE1/1 and GE2/1, which use the triple Gas Electron Multiplier (GEM) technology. ME0 is designed to cover the forward region of 2.0 < | η | < 2.8, thus improving muon reconstruction at high background rates by supplementing other overlapping muon subsystems up to | η | = 2.4, while also extending the acceptance for the first time to | η | = 2.8. The readout electronics for ME0 must be designed to accommodate high data rates and be sufficiently radiation hard to operate close to the beamline. The Optohybrid (OH) board for ME0, which reads out data from the front-end VFAT3b ASICs, has therefore been designed to operate without an FPGA (unlike GE1/1 and GE2/1) to ensure radiation hardness. The ME0 OH uses the radiation-hard CERN-designed lpGBT ASIC and VTRx+ optical transceiver module for high bandwidth optical links up to 10.24 Gb/s. The backend system is based on the ATCA standard. The design and development status of the readout electronics for ME0 is presented, along with recent results from integration tests performed using the first prototypes.

Instruments & Instrumentation↗

High Dose Rate Irradiations of Enduray Vision System for Nuclear Inspections

Higher radiation-hardened video cameras are needed in the operation and remote handling of equipment in nuclear reactor inspection and refueling applications. Vega Wave Systems, Inc. has developed a radiation-hardened vision system for nuclear energy applications. This vision system has been developed under several small business innovative research programs (SBIRs) from the U.S. Department of Energy, and the previous GAIN voucher program at Argonne National Laboratory (ANL) was successful in demonstrating that a prototype of the camera is radiation-hard up to at least 525 kGy (5.25 × 106 rad, Si equivalent) at dose rates of 10 kGy/hr with no measurable degradation in image quality and no measurable radiation-induced noise (RIN). Vega Wave Systems has developed a new version of the camera with more than 3X the resolution using a new design and new components, and this new design requires radiation-hardness qualification for marketplace acceptance. The program described in this report provided high radiation-hardness testing of this redesigned high-resolution vision system using the Argonne Low-Energy Accelerator Facility (LEAF). This report presents the results of irradiation tests performed on Vega Wave System’s redesigned high resolution vision system at a dose rate of 9.3 kGy/hr and up to total doses of 1823 kGy. This was an accumulation of 197 hours of irradiation. The results were excellent, providing proof of the redesigned high-resolution vision system’s immunity to high levels of radiation.

42 ENGINEERING↗

Development of readout electronics for the CMS ME0 muon detector

The Large Hadron Collider (LHC) in the High Luminosity (HL-LHC) era will be upgraded to deliver instantaneous luminosities up to 5 X 10 34 cm -2 s -1 , five times more than the original design value. In order to maintain performance of the Compact Muon Solenoid (CMS) Experiment under these conditions, ME0 is one of the new muon detectors to be added, along with GE1/1, GE2/1, RE3/1 and RE4/1. ME0 uses the triple Gas Electron Multiplier (GEM) technology and is designed to cover the far-forward region of 2.0 < |η| < 2.8. Further, the readout electronics for ME0 must be designed to deal with high data rates and be sufficiently radiation hard to operate very close to the beamline. The design and development status of the readout electronics for ME0 are presented, along with recent results from integration tests performed using the latest electronics prototypes with GEM chambers.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Advancing radioactive material research method: the development of a novel in situ particle-attached microfluidic electrochemical cell

This study aims to develop a microgram-scale microfluidic electrochemical cell (E-cell) for investigating the redox behavior of uranium oxide (UO 2 ). The traditional bulk electrochemical methods may require shielded facilities to investigate the hazardous materials, e.g., spent nuclear fuel, due to high radiation levels. Microfluidic E-cells offer advantages such as reduced radiation exposure, control over fluid flow rates, and high-throughput capabilities. Methods: The design of the E-cell considers electrode morphology, adhesion to a thin membrane, electrode configuration, and vacuum compatibility. Three techniques, including FIB-SEM lift-out, Au coating, and polyvinylidene fluoride (PVDF) binder, are explored for fabricating and attaching microgram quantities of UO 2 as working electrodes. The PVDF binder method proves to be the most effective, enabling the creation of a vacuum-compatible microfluidic E-cell. Results and discussion: The PVDF binder method demonstrates successful electrochemical responses and allows for real-time monitoring of UO 2 electrode behavior at the microscale. It offers chemical imaging capabilities using in situ SEM/EDS analysis. The technique provides consistent redox outcomes similar to bulk electrochemical analysis. Conclusion: The development of a microgram-scale microfluidic electrochemical cell using the PVDF binder technique enables the investigation of UO 2 redox behavior. It offers a low-risk approach with reduced radiation exposure and high-throughput capabilities. The technique provides real-time monitoring and chemical imaging capabilities, making it valuable for studying spent nuclear fuel systems and material characterization.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Sea ice and atmospheric circulation shape the high-latitude lapse rate feedback

Abstract Arctic amplification of anthropogenic climate change is widely attributed to the sea-ice albedo feedback, with its attendant increase in absorbed solar radiation, and to the effect of the vertical structure of atmospheric warming on Earth’s outgoing longwave radiation. The latter lapse rate feedback is subject, at high latitudes, to a myriad of local and remote influences whose relative contributions remain unquantified. The distinct controls on the high-latitude lapse rate feedback are here partitioned into “upper” and “lower” contributions originating above and below a characteristic climatological isentropic surface that separates the high-latitude lower troposphere from the rest of the atmosphere. This decomposition clarifies how the positive high-latitude lapse rate feedback over polar oceans arises primarily as an atmospheric response to local sea ice loss and is reduced in subpolar latitudes by an increase in poleward atmospheric energy transport. The separation of the locally driven component of the high-latitude lapse rate feedback further reveals how it and the sea-ice albedo feedback together dominate Arctic amplification as a coupled mechanism operating across the seasonal cycle.

54 ENVIRONMENTAL SCIENCES↗

HRPPD photosensors for RICH detectors with a high resolution timing capability

Recently, a new version of DC-coupled High Rate Picosecond Photodetectors (DC-HRPPDs) substantially re-designed for use at the Electron-Ion Collider (EIC) has been developed. A first batch of seven “EIC HRPPDs” was manufactured in early 2024. These HRPPDs are DC-coupled photosensors based on Micro-Channel Plates (MCPs) that have an active area of 104 mm by 104 mm, 32 × 32 direct readout pixel array at a pitch of 3.25 mm, peak quantum efficiency in excess of 30%, exceptionally low dark count rates and timing resolution of 15–20 ps for a single photon detection. As such, these photosensors are very well suited for Ring Imaging CHerenkov (RICH) detectors that can additionally provide high resolution timing capability, especially in a configuration where a detected charged particle passes through the sensor window, which produces a localized flash containing a few dozens of Cherenkov photons in it.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗