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This is the Welcome and Introduction presentation for the International Earth Science Constellation (ESC) Mission Operations Working Group (MOWG) meeting held in Albuquerque NM from September 27-29. It contains an org chart, charter, history, significant topics to be discussed, AquaAura 2017 inclination adjust maneuver calendar, a-train long range plans, upcoming events, and action items.
Introducing a physician without a professional title may reinforce bias in medicine by influencing perceived credibility. We evaluated differences in the use of professional titles in introductions of speakers at recent American Society for Radiation Oncology (ASTRO) Annual Meetings.
Cyanobacteria hold promise for renewable chemical production due to their photosynthetic nature, but engineered strains frequently display poor production characteristics. These difficulties likely arise in part due to the distinctive photoautotrophic metabolism of cyanobacteria. Here, in this work, we apply a genome-scale metabolic model of the cyanobacteria Synechococus sp. PCC 7002 to identify strain designs accounting for this unique metabolism that are predicted to improve the production of various biofuel alcohols (e.g. 2-methyl-1-butanol, isobutanol, and 1-butanol) synthesized via an engineered biosynthesis pathway. Using the model, we identify that the introduction of a large, non-native NADH-demand into PCC 7002's metabolic network is predicted to enhance production of these alcohols by promoting NADH-generating reactions upstream of the production pathways. To test this, we construct strains of PCC 7002 that utilize a heterologous, NADH-dependent nitrite reductase in place of the native, ferredoxin-dependent enzyme to create an NADH-demand in the cells when grown on nitrate-containing media. We find that photosynthetic production of both isobutanol and 2-methyl-1-butanol is significantly improved in the engineered strain background relative to that in a wild-type background. We additionally identify that the use of high-nutrient media leads to a substantial prolongment of the production curve in our alcohol production strains. The metabolic engineering strategy identified and tested in this work presents a novel approach to engineer cyanobacterial production strains that takes advantage of a unique aspect of their metabolism and serves as a basis on which to further develop strains with improved production of these alcohols and related products.
The novel use of a GaAs y P 1-y /GaP compressively-strained superlattice (CSS) to provide enhanced control over misfit dislocation (MD) evolution and threading dislocation density (TDD) during GaP/Si metamorphic heteroepitaxy is demonstrated. Here, the insertion of the CSS just after critical thickness, and thus prior to substantial dislocation introduction, is found to yield significantly reduced TDD in relaxed, 500 nm thick, n-type GaP/Si versus comparable control samples. The impact of CSS period count on average TDD and the overall dislocation network morphology was examined, supported by quantitative microstructural characterization, revealing a nearly 20× relative TDD reduction (to 2.4 ± 0.4×10 6 cm -2 ) with a 3-period CSS structure. A similarly low TDD (3.0 ± 0.6×10 6 cm -2 ) is maintained when the resultant n-GaP/Si virtual substrate is used for the growth of a subsequent n-type GaAs 0.75 P 0.25 -terminal GaAs y P 1-y step-graded metamorphic buffer. Although the physical mechanism for TDD reduction provided by these structures is not yet entirely understood, this initial work suggests that enhanced glide dynamics of MDs at or within the CSS placed early in the growth leads to a reduction in the total number of dislocations introduced overall, as opposed to annihilation-based reduction that occurs in conventional strained-layer superlattice dislocation filter approaches.
© The Royal Society of Chemistry 2020. Organic thermoelectric materials and generators are a promising field of research due to numerous attractive characteristics that suggest the ability to overcome the shortcomings of existing inorganic TE systems. This book aims to reprise some of the key directions in this field and provide some context on the key developments and opportunities that remain to be explored. Therefore, to facilitate comprehension of the book, this introduction chapter will present a brief overview of essential topics spanning the fields of chemistry, materials science, engineering, and physics, including a brief historical overview of organic TE materials. TE measurement techniques, including carrier-energy and thermal transport in organic TE systems, will also be briefly discussed, as they are relevant to understanding what challenges remain in understanding and optimizing the performance of these organic TE materials.
An introduction to the Nanoscale themed collection on halide perovskite nanomaterials for optoelectronic applications, featuring a variety of articles that highlight the latest developments to address ongoing challenges in the field.
Two type-I clathrates were synthesized by introducing Ga into the framework of the Ba 8 Cu 16 P 30 type-I clathrate. The introduction of minute amounts of Ga, 1.9% Ga/M total (where M total = Cu + Ga), resulted in the disturbance of the completely ordered Pbcn superstructure of Ba 8 Cu 16 P 30 . Ba 8 Cu 15.43(2) Ga 0.3 P 30.26(3) crystallizes in a partially ordered orthorhombic Pmna clathrate-I superstructure with five out of 15 framework sites being jointly occupied by metal+phosphorus. Increasing the Ga content resulted in all framework sites being occupied by metal + phosphorus in the archetype cubic Pm n clathrate-I crystal structure of Ba 8 Cu 14.5(3) Ga 1.3 P 30.2(4) with 8.2% Ga/M total . A combination of energy dispersive x-ray spectroscopy, inductively coupled plasma mass spectroscopy, and single crystal x-ray diffraction was used to determine the structures alongside the compositions. The positional disorder was verified by 31 P solid state NMR spectroscopy. Characterization of the transport properties indicated that the Ga-substituted samples exhibit higher Seebeck coefficients and electrical resistivities compared to its pristine counterpart, in line with the expected reduction of the hole concentration due to Ga/Cu substitution. Moderate improvements in the thermoelectric power factor and overall figure-of-merit were observed for samples with 6.9% and 3.8% Ga/M total as compared to those for the pristine Ba 8 Cu 16 P 30 clathrate. Finally, band structure calculations shed light on how Ga substitution affects the electronic structure and thermoelectric properties of studied clathrates.
Spectral line-shape models are an important part of understanding high-energy-density (HED) plasmas. Models are needed for calculating opacity of materials and can serve as diagnostics for astrophysical and laboratory plasmas. However, much of the literature on line shapes is directed toward specialists. This perspective makes it difficult for non-specialists to enter the field. We have two broad goals with this topical review. First, we aim to give information so that others in HED physics may better understand the current field. Additionally, this first goal may help guide future experiments to test different aspects of the theory. Second, we provide an introduction for those who might be interested in line-shape theory, and enough materials to be able to navigate the field and the literature. We give a high-level overview of line broadening process, as well as dive into the formalism, available methods, and approximations.
The International Tokamak Physics Activity (ITPA) has developed a comprehensive overview of the results of its coordinated R&D activities in fusion physics and diagnostics implemented during the past two decades with the aim of developing an improved physics basis for the operation of tokamak burning plasma experiments. Here, an introduction is presented to key concepts in the physics of burning plasmas in tokamaks, together with an overview of the scope of the principal areas of physics R&D pursued by the ITPA Topical Physics Groups in which the critical issues, major areas of progress and most significant recent results are highlighted. This paper introduces the following collection of articles, which encompass detailed presentations of the progress achieved by the Topical Groups in preparing the physics basis for the operation of tokamak burning plasma experiments expected to come into operation in the 2030s.
We are surrounded by all kinds of technology. Scientists and engineers have created amazing tools and resources, paved the way for multi-functional devices, and have put useful information at our finger tips. Software technology has enabled unprecedented levels of automation which has revolutionized our world and daily lives. Every year increasingly more data is collected and stored. Are we on the right track? This is an introduction to the new department on software technology.
African swine fever virus (ASFv) is a virulent pathogen that threatens domestic swine industries globally and persists in wild boar populations in some countries. Persistence in wild boar can challenge elimination and prevent disease-free status, making it necessary to address wild swine in proactive response plans. In the United States, invasive wild pigs are abundant and found across a wide range of ecological conditions that could drive different epidemiological dynamics among populations. Information on the size of the control areas required to rapidly eliminate the ASFv in wild pigs and how this area should change with management constraints and local ecology is needed to optimize response planning. We developed a spatially explicit disease transmission model contrasting wild pig movement and contact ecology in two ecosystems in Southeastern United States. We simulated ASFv spread and determined the optimal response area (reported as the radius of a circle) for eliminating ASFv rapidly over a range of detection times (when ASFv was detected relative to the true date of introduction), culling capacities (proportion of wild pigs in the culling zone removed weekly) and wild pig densities. Large radii for response areas (14 km) were needed under most conditions but could be shortened with early detection (≤ 8 weeks) and high culling capacities (≥ 15% weekly). Under most conditions, the ASFv was eliminated in less than 22 weeks using optimal control radii, although ecological conditions with high rates of wild pig movement required higher culling capacities (≥ 10% weekly) for elimination within 1 year. The results highlight the importance of adjusting response plans based on local ecology and show that wild pig movement is a better predictor of the optimal response area than the number of ASFv cases early in the outbreak trajectory. Furthermore, our framework provides a tool for determining optimal control plans in different areas, guiding expectations of response impacts, and planning resources needed for rapid elimination.
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, with >365,000 cases in California as of 17 July 2020. We investigated the genomic epidemiology of SARS-CoV-2 in Northern California from late January to mid-March 2020, using samples from 36 patients spanning nine counties and the Grand Princess cruise ship. Phylogenetic analyses revealed the cryptic introduction of at least seven different SARS-CoV-2 lineages into California, including epidemic WA1 strains associated with Washington state, with lack of a predominant lineage and limited transmission among communities. Lineages associated with outbreak clusters in two counties were defined by a single base substitution in the viral genome. These findings support contact tracing, social distancing, and travel restrictions to contain the spread of SARS-CoV-2 in California and other states.
Code accompanying the "Introduction to Machine Learning" short course for the 2022 IEEE NSS MIC RTSD conference.
In this introduction, we provide an overview of the papers that were accepted for publication in the feature issue on ultrafast phenomena and terahertz (THz) waves. This feature issue presents cutting-edge research on ultrafast phenomena and highlights recent developments in THz technology.
This data package is associated with the publication "Integrated, Coordinated, Open, and Networked (ICON) Science to Advance the Geosciences: Introduction and Synthesis of a Special Collection of Commentary Articles" in Earth and Space Science (Goldman et al. 2022; https://doi.org/10.1029/2021EA002099). The manuscript is an introductory article for a special collection of commentary articles across 19 geoscience disciplines that explore the challenges and opportunities associated with the use of ICON science principles. These principles focus on research intentionally designed to be Integrated, Coordinated, Open, and Networked (ICON) with the goal of maximizing mutual benefit (among stakeholders) and cross-system transferability of science outcomes. This data package contains data, figures, and R scripts associated with the cost/benefit analysis presented in the manuscript. The writing teams involved in the special collection placed each letter of ICON on a plot with perceived cost on one axis and perceived benefit on the other to summarize their perceptions of pursuing each principle of ICON science. These data were subsequently quantified and analyzed. Files are saved as .csv, .R, and .pdf. This data package also contains (1) the public foundational and instructional documents that enabled the crowdsourced creation of the special collection; (2) file-level metadata (flmd) that lists each file in the data package with a description; (3) data dictionary (dd) that defines column headers that appear in csv files. Files are saved as .pdf and .csv.
This report provides a comprehensive overview of metadata to describe sensor signals in wastewater treatment plants and methods to obtain such metadata. In this introduction, we explain the original motivation behind the MetaCO task group. This includes a description of historical challenges (data volume, data velocity) for which mature technology is now available, and newer challenges, which relate to data structure (data variety) and data quality (veracity). We conclude the chapter with an expression of gratitude to all involved.
The following guide is a tutorial-style introduction to the free Lagrange (FLAG) hydrocode for anyone who wants to get started with or learn more about FLAG.
The presentation is an introduction to earth system modeling, including motivation, tools, and challenges.