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NASA NTRS1991

Space mechanisms needs for future NASA long duration space missions

Future NASA long duration missions will require high performance, reliable, long lived mechanical moving systems. In order to develop these systems, high technology components such as bearings, gears, seals, lubricants, etc., will need to be utilized. There has been concern in the NASA community that the current technology level in these mechanical component/tribology areas may not be adequate to meet the goals of long duration NASA mission such as Space Exploration Initiative (SEI). To resolve this concern, NASA-Lewis sent a questionnaire to government and industry workers (who have been involved in space mechanism research, design, and implementation) to ask their opinion if the current space mechanisms technology (mechanical components/tribology) is adequate to meet future NASA Mission needs and goals. In addition, a working group consisting of members from each NASA Center, DoD, and DOE was established to study the technology status. The results of the survey and conclusions of the working group are summarized.

Fusaro, Robert L.↗

NASA NTRSDate not supplied

Bionutrients-1: Utilizing Genomics and Transcriptomics to Assess the Reliability of Microorganisms for In Situ Nutrient Production on Long Duration Missions

The resupply of current long-duration crewed missions to the ISS relies on ground-launched supplies. As NASA looks toward Mars, ground-based resupply will no longer be an option. Critical nutrients, including vitamin C, vitamin K, folate, and thiamin, degrade during long-term storage, and regular consumption of these nutrients is essential for astronaut health. Another challenge of current food systems is the difficulty of consuming sufficient calories when subsisting on the limited flavors of freeze-dried food, which can lead to weight loss. The inclusion of microorganism-based food systems could alleviate both concerns. For example, the fermentation of rehydrated milk into yogurt with microorganisms genetically incorporating genes to produce critical vitamins would allow for both in situ production of nutrients and a fresh food product with additional flavor profiles. In comparison to plant food production, microorganisms require less flight infrastructure. The BioNutrients-1 mission is demonstrating viability of microbial fermentation food production in microgravity and testing the reliability of this approach for long-duration missions lacking resupply. While the BioNutrients-1 mission includes the collection of multiple phenotypic measurements, this status update will focus on the processing of samples for genomics and transcriptomics analyses as well as the planned analysis pipelines. First, the BioNutrients-1 mission seeks to identify microorganisms capable of surviving long-duration storage at ambient temperatures while maintaining genetic fidelity. To achieve this, nine commonly employed microbial species were stored at ambient temperatures in Stasis Packs on the ISS for five years. The viability and mutation rates will be measured at multiple time points for both flown and ground control samples. From an omics perspective, the changes in the bulk rates of point mutations and genetic rearrangements across the Stasis Pack species during the five years of storage will be determined, providing valuable insights into the potential of these microorganisms for long-duration space missions. Second, the BioNutrients-1 mission is characterizing the impact of microgravity on fermentation. Two strains of the yeast Saccharomyces cerevisiae, each encoding antioxidants (β-carotene or zeaxanthin) were flown to ISS for storage and fermentation within simplified bioreactors (Production Packs). The impact of microgravity on the expression of the antioxidant production genes and general metabolic genes will be determined using RNA sequencing. Ultimately, the transcriptome data will be compared to phenotypic measurements, such as the antioxidant yield, end-state biomass, and the production of EtOH, to determine the impacts of microgravity and long-term storage on microbial fermentation. The findings from this research will be instrumental in understanding the challenges and opportunities of microorganism-based food systems in space missions.

BioNutrients↗

NASA NTRSDate not supplied

Smart Habitat: Identifying Technological Countermeasures to Address Health and Performance Risks during Long-Duration Exploration Missions

During proposed long-duration Exploration Missions, crews must become increasingly autonomous, as they will be unable to rely on consistent input and guidance from ground-based mission control operations. While it is known that smart technologies will play a crucial role in future long-duration Exploration Missions, it is not known which manner of devices and systems may best mitigate the expected risks to crew. The purpose of this project was to identify both current and emerging technologies which may act as health and performance countermeasures on long-duration Exploration Missions.

Ryan A. Lange↗

NASA NTRSDate not supplied

Designing Autonomy into Interfaces for Long-Duration Missions

As NASA develops technologies for long-duration crewed missions, we must understand how communication between ground control teams and astronauts differs from the current dynamic to adapt new concepts for long-duration mission operations. Today, ground control teams support astronauts with immediate availability to answer questions, resolve issues, and manage activities. In the near future, however, extended communication delays during long-duration missions will require astronauts to become more autonomous. As many of the responsibilities shift from the ground control teams to the astronauts on-board, the concept of operations must also change from how it functions today. With increased astronaut autonomy, software tools must be developed that enable efficient completion of mission tasks without increased mental workload. Designing software tools to facilitate crew autonomy requires development teams to know which data will enhance quick decision making while providing necessary context for situational awareness of systems being managed on-board. NASA's Autonomous Systems and Operations (ASO) team is presently developing a software interface tool, EXPRESS (EXpedite the PRocessing of Experiments for Space Station) 2.5 to enable a long-duration crew to schedule activities for and operate autonomous systems. This paper describes details of the integrated human factors approach that drove the design of the elements of the software tool, including self-managed scheduling, constraint-driven planning, autonomous system fault recovery, and recommended troubleshooting actions. Additionally, this paper will chronicle ASO modifications of the user interface after the team's first flight demonstration, how it was based on lessons learned during software development, as well as from crew feedback in order to develop the current version which will be demonstrated on ISS in 2021. In the upcoming ISS demonstration, the astronaut crew will be given scenarios for scheduling and operating autonomous system activities, including off-nominal scenarios and autonomous system recoveries. The demonstration of the EXPRESS 2.5 tool is a step towards improved levels of autonomy as our new journeys take us farther into space.

autonomy↗

NASA NTRSDate not supplied

BioNutrients-1: Development of an On-Demand Nutrient Production System for Long-Duration Missions

Future long-duration missions beyond low-Earth orbit will require advances in food technologies to address the documented problem of degradation of vitamins and nutrients in supplied foods stored long-term. To begin to address the issue of nutrient degradation, we are developing and flight-testing a platform biomanufacturing technology for in situ production of target nutrients. This technology is being tested over a five-year duration on the International Space Station (ISS). As part of the BioNutrients-1 project we have developed an on-demand system for the production of two carotenoids, β-carotene and zeaxanthin, by genetically engineering distinct strains of Saccharomyces cerevisiae, more commonly known as baker’s yeast. The on-orbit nutrient production packs contain a desiccated yeast strain and edible growth substrate. Once hydrated, the contents of the production packs are intended to grow and produce a desired amount of ready-to-consume nutrients. In this current version the production packs will not be consumed and future missions will require an inactivation of microorganisms before consumption. In addition to the on-orbit hydration of the production packs a series of valuable microorganisms are currently being stored in stasis packs on the ISS including probiotics organisms, bacterial strains used in yogurt production, and organisms with potential use for future biomanufacturing. Analysis of returned ISS stasis packs and ground controls will include multi-omics studies and provide insight into long-term survival of organisms stored in a space environment. Both stasis packs and hydrated production packs will be intermittently returned to Earth for analysis. Preliminary data from long-term storage studies of stasis packs stored on the ISS for 47 days versus their ground control counterparts have shown no significant difference in viability. Currently no production packs have been processed.

Yeast↗

NASA NTRS2019

Power Systems Design for Long Duration Ballooning

The Columbia Scientific Balloon Facility (CSBF) has been designing and building high-altitude balloon power systems for over 28 years. With that experience, we have found certain types of PV panels, batteries, and charge controllers that are reliable in stratospheric environments. The goal is to ensure that power systems provide power reliably throughout the duration of an Long Duration Ballooning (LDB) flight. The purpose of this presentation is to provide some general guidelines and best practices for power system design.

Long Duration Ballooning↗

NASA NTRS2010

Bone Density Following Three Years of Recovery from Long-Duration Space-Flight

Bone loss during long-duration space flight is well recognized, but the long-term implications on bone health following return from flight remain unclear. Among US crew who were involved in long-duration missions in space (Mir and ISS), we have previously shown that at approximately 12 months following return, men, but not women, had BMD values at most sites that were still lower than would be expected had they not been exposed to a prolonged period of microgravity. We now extend our observations to 3 years of follow-up post-flight. Using their age, pre-flight BMD and follow-up time, post-flight BMD values for each US crew were predicted based on the model developed from the community sample. We found BMD measures to be either stable or improve by 3 years relative to their immediate post-flight BMD, however only total hip BMD still remains significantly lower than would be expected had they not been exposed to microgravity. Among male US crew, who have had their BMD measured following at least 3 years of recovery post long-duration flight, they continue to have lower BMD at the hip than would be expected, raising potential concerns regarding future hip fracture risk.

Amin, S.↗

NASA NTRS1982

Thermal design and experiment thermal integration of the Long Duration Exposure Facility

The Long Duration Exposure Facility (LDEF) is a large (14 feet diameter by 30 feet long) Shuttle transported, reusable spacecraft. The LDEF can accommodate up to 13,000 pounds of experiments mounted in 86 standard trays. This paper describes the philosophy and approach used for the passive thermal design of the LDEF. Also discussed are the standardized guidelines and techniques used in the thermal design and integration of approximately 50 different thermally passive experiments. A technique for reducing multinode thermal models of experiments to 2 nodes is also presented. This approach allows the efficient thermal integration of large numbers of experiments with the LDEF spacecraft.

Greene, R. F., Jr.↗

NASA NTRS2000

Comparison of Echocardiographic Measurements Before and After Short and Long Duration Spaceflight

Previous echocardiography studies in astronauts before and after short duration (4 - 17 days) missions have demonstrated a decrease in resting left ventricular (LV) stroke volume (SV), but maintained ejection fraction (EF) and cardiac output. Similar studies before and after long duration (129 - 144 days) spaceflight have been rare and their overall results equivocal. The purpose of this work was to compare the echocardiographic measurements (M-mode, 2-D and Doppler) from short duration (n = 13) and long duration (n = 4) crewmembers. Compared to short duration astronauts, long duration crewmembers had a significantly greater percent decrease in EF (+6+/-0.02 vs.-10.5+/-0.03, p = 0.005) and percent fractional shortening (+7+/-0.03 vs. -11+/-0.07, p = 0.0 15), and an increase in LV end systolic volume (-12+/-0.06 vs. +39+/-0.24, p = 0.011). These data suggest a reduction in cardiac function that relates to mission duration. As the changes in blood pressure and circulating blood volume (9% - 12%) are reported to be similar after short and long duration flights, the drop in EF after longer spaceflights is likely due to a decrease in cardiac function rather than altered blood volume.

Fritsch-Yelle, Janice M.↗

NASA NTRS2016

Long Duration Sorbent Testbed

The Long Duration Sorbent Testbed (LDST) is a flight experiment demonstration designed to expose current and future candidate carbon dioxide removal system sorbents to an actual crewed space cabin environment to assess and compare sorption working capacity degradation resulting from long term operation. An analysis of sorbent materials returned to Earth after approximately one year of operation in the International Space Station's (ISS) Carbon Dioxide Removal Assembly (CDRA) indicated as much as a 70% loss of working capacity of the silica gel desiccant material at the extreme system inlet location, with a gradient of capacity loss down the bed. The primary science objective is to assess the degradation of potential sorbents for exploration class missions and ISS upgrades when operated in a true crewed space cabin environment. A secondary objective is to compare degradation of flight test to a ground test unit with contaminant dosing to determine applicability of ground testing.

Howard, David F.↗

NASA NTRS1991

Meteoroid and orbital debris record of the Long Duration Exposure Facility

The Long Duration Exposure Facility (LDEF) was recovered in January 1990 following 5.7 years exposure of approx. 130 square meters of surface area in low-Earth orbit (250-179 miles). Kennedy Space Center acquired data are currently being reduced to yield accurate impact crater depths and diameters. Presented here is a preliminary accounting of the impact record based on the approx. 15.4 square meter surface area of LDEF's 6061-T6 aluminum frame, which was exposed in 26 different directions.

Zolensky, Mike↗

NASA NTRS1991

Light as a chronobiologic countermeasure for long-duration space operations

Long-duration space missions require adaptation to work-rest schedules which are substantially shifted with respect to earth. Astronauts are expected to work in two-shift operations and the environmental synchronizers (zeitgebers) in a spacecraft differ significantly from those on earth. A study on circadian rhythms, sleep, and performance was conducted by exposing four subjects to 6 deg head-down tilt bedrest (to simulate the effects of the weightless condition) and imposing a 12-h shift (6 h delay per day for two days). Bright light was tested in a cross-over design as a countermeasure for achieving faster resynchronization and regaining stable conditions for sleep and circadian rhythmicity. Data collection included objective sleep recording, temperature, heart rate, and excretion of hormones and electrolytes as well as performance and responses to questionnaires. Even without a shift in the sleep-wake cycle, the sleep quantity, circadian amplitudes and 24 h means decreased in many functions under bedrest conditions. During the shift days, sleepiness and fatigue increased, and alertness decreased. However, sleep quantity was regained, and resynchronization was completed within seven days after the shift for almost all functions, irrespective of whether light was administered during day-time or night-time hours. The time of day of light exposure surprisingly appeared not to have a discriminatory effect on the resynchronization speed under shift and bedrest conditions. The results indicate that simulated weightlessness alters circadian rhythms and sleep, and that schedule changes induce additional physiological disruption with decreased subjective alertness and increased fatigue. Because of their operational implications, these phenomena deserve additional investigation.

Samel, Alexander↗

NASA NTRS1995

Long Duration Exposure Facility

The Long Duration Exposure Facility (LDEF) materials were useful for testing technical concepts that needed to be validated for the Cosmic Dust Collector Facility (CDCF) - a large instrument that was under study for inclusion on the upcoming Space Station. As it turned out, CDCF, which was approved at one point as an external payload, was ultimately canceled due to the scaling back of the Space Station capabilities. However, the study of cosmic dust is still a field of great interest for NASA, being the crucial part of at least one experiment that is still being considered for a Discovery mission. The optimum analysis of hypervelocity impacts is thus a continuing NASA concern. Two experiments, AO187-1 and AO187-2 were explicitly designed to measure the flux and composition of dust particles impacting LDEF. The former consisted of flat targets of Au and Al while the second comprised a set of 237 "capture cells" using Ge target plates covered by thin (2.5 microns) metallized plastic foils. The spacecraft maintained a constant orientation with respect to its velocity vector thereby defining leading and trailing edges that faced respectively into and away from the direction of motion. Both AO187-1 and AO187-2 had detectors on both the leading and trailing edges of LDEF. It was expected that interplanetary dust particles would dominate impacts on the trailing edge while the leading edge would be exposed to both cosmic dust and particles of orbital manmade debris. In AO187-1, the compositions of the impactors was determined by SEM-EDS techniques; in AO187-2 a sensitive surface analysis technique - SIMS - was used to determine both elemental and (some) isotopic compositions. In the initial analysis of AO187-2, it was found that SIMS was more sensitive for the analysis of thin impact debris layers than SEM-EDS. The present grant was made to determine if SIMS analysis could also be applied to impacts recorded in the Au surfaces of AO187-1. Success would extend the analysis of AO187-1 and would also contribute important technical information for the design of future cosmic dust space missions. The results obtained with this grant are incorporated in the attached paper presented at the Third LDEF Symposium and are briefly summarized here. In addition, we comment on the potential implications of this work for future research.

Source record↗

NASA NTRS2000

Artificial gravity as a countermeasure in long-duration space flight

Long-duration exposure to weightlessness results in bone demineralization, muscle atrophy, cardiovascular deconditioning, altered sensory-motor control, and central nervous system reorganizations. Exercise countermeasures and body loading methods so far employed have failed to prevent these changes. A human mission to Mars might last 2 or 3 years and without effective countermeasures could result in dangerous levels of bone and muscle loss. Artificial gravity generated by rotation of an entire space vehicle or of an inner chamber could be used to prevent structural changes. Some of the physical characteristics of rotating environments are outlined along with their implications for human performance. Artificial gravity is the centripetal force generated in a rotating vehicle and is proportional to the product of the square of angular velocity and the radius of rotation. Thus, for a particular g-level, there is a tradeoff between velocity of rotation and radius. Increased radius is vastly more expensive to achieve than velocity, so it is important to know the highest rotation rates to which humans can adapt. Early studies suggested that 3 rpm might be the upper limit because movement control and orientation were disrupted at higher velocities and motion sickness and chronic fatigue were persistent problems. Recent studies, however, are showing that, if the terminal velocity is achieved over a series of gradual steps and many body movements are made at each dwell velocity, then full adaptation of head, arm, and leg movements is possible. Rotation rates as high as 7.5-10 rpm are likely feasible. An important feature of the new studies is that they provide compelling evidence that equilibrium point theories of movement control are inadequate. The central principles of equilibrium point theories lead to the equifinality prediction, which is violated by movements made in rotating reference frames. Copyright 2000 Wiley-Liss, Inc.

Review Literature↗

NASA NTRS2005

We Have the Spaceship; But Where's the Start Button: Human Engineering Issues in the Age of Long Duration Space Exploration

As long duration space exploration and habitation becomes more commonplace, a number of Human Engineering factors (Gravitational Adaptation, 2-D to 3-D Movement Adaptation, Design Form/Function, and Space Ergonomics to name a few) will become more pronounced. More research and development is needed in these areas or the explorers may find themselves in painful or dangerous situations.

Hamilton, George S.↗

NASA NTRS2011

Development of a Rover Simulation to Assess Operational Proficiency Following Long Duration Spaceflights

Following long-duration space transits, adaptive changes in sensorimotor and cognitive function may impair the crew s ability to safely control pressurized rovers designed to explore the new environment. We describe a rover simulation developed to quantify post-flight decrements in operational proficiency following International Space Station expeditions. The rover simulation consists of a serial presentation of discrete tasks to be completed as quickly and accurately as possible. Each task consists of 1) perspective taking using a map that defines a docking target, 2) navigation toward the target around a Martian outpost, and 3) docking a side hatch of the rover to a visually guided target. The simulator utilizes a Stewart-type motion base (CKAS, Australia), single seat cabin with triple scene projection covering approximately 150 horizontal by 40 vertical, and joystick controller. The software was implemented using Unity3 with next-gen PhysX engine to tightly synchronize simulation and motion platform commands. Separate C# applications allow investigators to customize session sequences with different lighting and gravitational conditions, and then execute tasks to be performed as well as record performance data. Preliminary tests resulted in low incidence of motion sickness (<15% unable to complete first session), with only negligible after effects and symptoms after familiarization sessions. Functionally relevant testing early post-flight will develop evidence regarding the limitations to early surface operations and what countermeasures are needed. This approach can be easily adapted to other vehicle designs to provide a platform to safely assess how sensorimotor and cognitive function impact manual control performance.

DeDios, Y. E.↗

NASA NTRS2011

Assessment of Proficiency During Simulated Rover Operations Following Long-Duration Spaceflight

Following long-duration space travel, pressurized rovers will enhance crew mobility to explore Mars and other planetary surfaces. Adaptive changes in sensorimotor function may limit the crew s proficiency when performing some rover operations shortly after transition to the new gravitoinertial environment. The primary goal of this investigation is to quantify postflight decrements in operational proficiency in a motion-based rover simulation after International Space Station (ISS) expeditions. Given that postflight performance will also be influenced by the level of preflight proficiency attained, a ground-based normative study was conducted to characterize the acquisition of skills over multiple sessions.

Wood, S. J.↗

NASA NTRS2014

Assessment of Proficiency During Simulated Rover Operations Following Long-Duration Spaceflight

Beltran, E. J.↗