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Guidelines for Assessing the Toxic Hazard of Spacecraft Chemicals and Test Materials

This document describes the criteria and procedural guidelines used by the NASA/JSC Toxicology Office (JSCSTO), to perform toxicological evaluations. The JSCSTO is responsible for conducting toxicological assessments and assigning toxic hazard levels (THLs) for essentially all chemicals and test materials to be used in or transported to the habitable areas of U.S. spacecraft, non‐U.S. spacecraft inhabitaed by U.S. crew members or habitable areas of off‐Earth habitats where U.S. crew members would be present, including chemicals carried by visiting spacecraft(visiting vehicles) to and from the International Space Station (ISS). Biohazard assessments for biological materials used in payload experiments are performed by the NASA Biosafety Review Board. Radioactive materials are assessed by the Space Radiation Analysis Group for radiation hazards; the flammability rating on flammable materials is assessed by the JSC Materials and Processes Branch, ES4. This document will focus on the assessment of chemically‐induced toxicity hazards. The toxicological assessments, together with assessments on radioactive, biological, physical, and flammability hazards, are incorporated into a mission‐specific Hazardous Materials Summary Table (HMST).

Valerie Elizabeth Ryder↗

Impact of Jovian radiation environmental hazard on spacecraft and mission development design

The environmental impact on the TOPS 12L configuration is discussed. The activities in system environmental design and testing are described, and radiation design restraints based on the upper limit model are given. Range energy cutoffs in aluminum are also presented and the effective shielding thicknesses for electrons and protons of different energies are included. Design integration problems and radiation testing aspects are considered. Data are given for selecting the parts which should be tested in a formal test program, and the piece-part radiation thresholds are tabulated for electrons and protons.

Divita, E.↗

Lunar mission safety and rescue: Hazards analysis and safety requirements

The results are presented of the hazards analysis which was concerned only with hazards to personnel and not with loss of equipment or property. Hazards characterization includes the definition of a hazard, the hazard levels, and the hazard groups. The analysis methodology is described in detail. The methodology was used to prepare the top level functional flow diagrams, to perform the first level hazards assessment, and to develop a list of conditions and situations requiring individual hazard studies. The 39 individual hazard study results are presented in total.

Source record↗

Dosimetry during space missions

Comparative radiation hazards due to various sources of radiation in several prominent manned space missions are surveyed, along with techniques for coping with the hazards. Cosmic radiation of solar and galactic origin, and Van Allen belt radiation, are the major hazards outside the earth's geomagnetic shield, and were a major problem in the Apollo missions. The Skylab missions, while within the geomagnetic field, were subject to extensive exposure to the trapped radiation belts (Van Allen belts), while the Soyuz-Apollo test project involved orbiting at a lower altitude, with lower exposure. No solar particle bursts affected Apollo missions, and the Solar Particle Alert Network devised to help cope with the problem is described. Dosimetry practices and devices are described. Radiation experience and dose readings logged with the various missions are reported.

Bailey, J. V.↗

CST: A Tool for Optimizing the Efficiency and Effectiveness of Static-Code Analysis Tools

Static Code Analysis (SCA) is a vital component of NASA IV&V’s mission assurance for safety-critical software as it reduces the likelihood of software-induced hazards impacting mission success. Static Code Analysis achieves this by identifying hazards that may not have been otherwise detectable by typical code reviews or other testing. Using SCA tools, however, can be intimidating due to steep learning curves, especially considering tool performance and defect coverage varies greatly. Because of this variation amongst SCA tools, understanding which tools support certain defects and which do not, as well as understanding how to run an analysis based on steps that are unique to each tool, can be difficult to both new and experienced analysts alike. To mitigate this, the SCAWG or the IV&V Static Code Analysis Working Group, created the SCA Checker Taxonomy and Starting Point Profiles. The Checker Selection Tool (CST) incorporates these two SCAWG products into an interactive tool which allows the user to: select organized categories of defects they would like the SCA tools to discover, select default checkers depending on their mission type (e.g. flight), and configure multiple SCA tools at once. C/C++, Java, and Python defect checkers from four common SCA tools were utilized in this iteration of the CST. This iteration also includes the addition of training, SCA tool specific help, and taxonomy guide links, into its design to help users new to Static Code Analysis learn how to perform SCA more efficiently. The CST has been subject to beta testing by experienced static code analysts from the SCAWG to ensure a usable and accurate final product. The implications of the CST in the mission assurance of NASA safety-critical software are profound, as the CST can help identify and reduce false positives and false negatives, fundamentally improving overall SCA efficiency and accuracy.

static code analysis↗

The Exploration Portable Electrostatic Detector (xPED)

Astronauts and rovers, while exploring dynamic environments, can experience charge buildup through Tribo-charging (contact electrification). Charge levels can become substantially high. especially in areas where photoelectric and plasma currents are reduced (e.g. lunar polar crater). Tribo-charging in areas that have little to no charge dissipative path can be severe, leaving an astronaut or roving object to remain charged for extended periods of time. Charge buildup on space suits and/or rovers is expected to present significant hazards to missions, such as electrostatic discharge and arcing, dust adhesion to space suits/equipment, and destruction of equipment. The avoidance of hazards associated with charge buildup is critical for future NASA missions to near earth objects, the Moon and Mars. The Exploration Portable Electrostatic Device (xPED) will allow astronauts to determine their charge state, and also characterize the electrical environment from their excursions. xPED would benefit manned, as well as robotic missions.

Jackson, Telana L.↗

Los Alamos RAGE Simulations of the HAIV Mission Concept

The mitigation of potentially hazardous objects (PHOs) can be accomplished by a variety of methods including kinetic impactors, gravity tractors and several nuclear explosion options. Depending on the available lead time prior to Earth impact, non- nuclear options can be very effective at altering a PHOs orbit. However if the warning time is short nuclear options are generally deemed most effective at mitigating the hazard. The NIAC mission concept for a nuclear mission has been presented at several meetings, including the last PDC (2013).We use the adaptive mesh hydrocode RAGE to perform detailed simulations of this Hypervelocity Asteroid Intercept Vehicle (HAIV) mission concept. We use the RAGE code to simulate the crater formation by the kinetic impactor as well as the explosion and energy coupling from the follower nuclear explosive device (NED) timed to detonate below the original surface to enhance the energy coupling. The RAGE code has been well validated for a wide variety of applications. A parametric study will be shown of the energy and momentum transfer to the target 100 m diameter object: 1) the HAIV mission as planned; 2) a surface explosion and 3) a subsurface (contained) explosion; both 2) and 3) use the same source energy as 1).Preliminary RAGE simulations show that the kinetic impactor will carve out a surface crater on the object and the subsequent NED explosion at the bottom of the crater transfers energy and momentum to the target effectively moving it off its Earth crossing orbit. Figure 1 shows the initial (simplified) RAGE 2D setup geometry for this study. Figure 2 shows the crater created by the kinetic impactor and Figure 3 shows the time sequence of the energy transfer to the target by the NED.

Asteroid Mitigation↗

Integrating Safety and Mission Assurance into Systems Engineering Modeling Practices

During the early development of products, flight, or experimental hardware, emphasis is often given to the identification of technical requirements, utilizing such tools as use case and activity diagrams. Designers and project teams focus on understanding physical and performance demands and challenges. It is typically only later, during the evaluation of preliminary designs that a first pass, if performed, is made to determine the process, safety, and mission quality assurance requirements. Evaluation early in the life cycle, though, can yield requirements that force a fundamental change in design. This paper discusses an alternate paradigm for using the concepts of use case or activity diagrams to identify safety hazard and mission quality assurance risks and concerns using the same systems engineering modeling tools being used to identify technical requirements. It contains two examples of how this process might be used in the development of a space flight experiment, and the design of a Human Powered Pizza Delivery Vehicle, along with the potential benefits to decrease development time, and provide stronger budget estimates.

Requirements↗

Human System Risk Communication: Directed Acyclic Graphs

- The Human System Risk Board (HSRB) is responsible for the management of a portfolio of 30 human system risks that NASA tracks and configuration manages to mitigate for future crewed exploration missions. - The HSRB has been exploring the concept of causal diagrams (in the form of Directed Acyclic Graphs or DAGs) as an approach to creating knowledge graphs for each risk to enable shared mental models of causal flow from spaceflight hazards to mission outcomes among HSRB Stakeholders. - These diagrams are intended to improve insight and communication of risk across the myriad subject matter experts and management interested in human system risk reduction. This includes program managers, systems engineers, and operators in addition to the Human Health and Performance Directorate. - The DAG project was intended to create the foundation for composition of the 30 baselined DAGs into a single risk network and software is being developed in parallel to enable this forward work.

directed acrylic graph↗

Expanding Repository Data Available For Sharing and Knowledge Discovery

Some of the hardest space biology and space health challenges require data-intensive, bioinformatic, meta-analytical, and computer-assisted research approaches. These challenges include examining interdisciplinary space life science research across experiments and across interacting spaceflight hazards (radiation, altered gravity, confinement, hostile-closed environments, distance-duration from Earth). The approaches to confront these challenges involve mining multiple datasets simultaneously from various hierarchical organizations of biological complexity, all while concurrently evaluating how experimental design factors affect endpoints of standard assays. To enable this field, it is essential that principal investigators (PIs) submit data in a structure so it can be maximally re-used. The purpose of the NASA Ames Life Sciences Data Archive (ALSDA) is to collect, curate, and make publicly available all non-human space-relevant biological data. ALSDA must also ensure data are open-access, and maximally findable, accessible, interoperable, and reusable (FAIR). The scope of ALSDA data collected and submitted by PIs include subject and study design metadata, assay metadata parameters, raw and processed assay data, assay imagery/video, and subject-experienced mission data telemetry (radiation, temperature, humidity, acoustics, vibrations, etc.). ALSDA recently integrated into a collaborative group of Open Science projects to facilitate a suite of new tools and workflows that will improve data submission, accessibility, and reusability by implementing digital data submission agreements, and adopting the data management system originally developed by NASA GeneLab. ALSDA intends to bring current biological repository data and all future collected data into this new scientific data reuse reality. This new suite of tools will enable ALSDA to deploy a science curation system using scientific assay configurations for the data submission portal. It will capture essential assay parameters according to established standards in each sub-field within biology. The submission portal expedites data collection by enhancing ease of PI data submission, providing a user interface and specificity for which data is to be submitted. Data submissions can be brought into cutting-edge informatic analysis portals to enable mining of physiological, behavioral, biochemical, and imaging datasets in conjunction with ‘omics-level datasets. As ALSDA datasets are submitted, curated, and published (e.g., micro-computed tomography, histology, pulse oximetry, serum metabolites, magnetic resonance imaging, intraocular pressure, novel object recognition, etc.), the merging together of spaceflight data along this multi-hierarchical complexity of biology will enable informatics and data-intensive approaches resulting in knowledge discoveries across missions, space hazards, and biological disciplines.

Biology↗

Expanding Repository Data Available For Sharing And Knowledge Discovery

Some of the hardest space biology and space health challenges require data-intensive, bioinformatic, meta-analytical, and computer-assisted research approaches. These challenges include examining interdisciplinary space life science research across experiments and across interacting spaceflight hazards (radiation, altered gravity, confinement, hostile-closed environments, distance-duration from Earth). The approaches to confront these challenges involve mining multiple datasets simultaneously from various hierarchical organizations of biological complexity, all while concurrently evaluating how experimental design factors affect endpoints of standard assays. To enable this field, it is essential that principal investigators (PIs) submit data in a structure so it can be maximally re-used. The purpose of the NASA Ames Life Sciences Data Archive (ALSDA) is to collect, curate, and make publicly available all non-human space-relevant biological data. ALSDA must also ensure data are open-access, and maximally findable, accessible, interoperable, and reusable (FAIR). The scope of ALSDA data collected and submitted by PIs include subject and study design metadata, assay metadata parameters, raw and processed assay data, assay imagery/video, and subject-experienced mission data telemetry (radiation, temperature, humidity, acoustics, vibrations, etc.). ALSDA recently integrated into a collaborative group of Open Science projects to facilitate a suite of new tools and workflows that will improve data submission, accessibility, and reusability by implementing digital data submission agreements, and adopting the data management system originally developed by NASA GeneLab. ALSDA intends to bring current biological repository data and all future collected data into this new scientific data reuse reality. This new suite of tools will enable ALSDA to deploy a science curation system using scientific assay configurations for the data submission portal. It will capture essential assay parameters according to established standards in each sub-field within biology. The submission portal expedites data collection by enhancing ease of PI data submission, providing a user interface and specificity for which data is to be submitted. Data submissions can be brought into cutting-edge informatic analysis portals to enable mining of physiological, behavioral, biochemical, and imaging datasets in conjunction with ‘omics-level datasets. As ALSDA datasets are submitted, curated, and published (e.g., micro-computed tomography, histology, pulse oximetry, serum metabolites, magnetic resonance imaging, intraocular pressure, novel object recognition, etc.), the merging together of spaceflight data along this multi-hierarchical complexity of biology will enable informatics and data-intensive approaches resulting in knowledge discoveries across missions, space hazards, and biological disciplines.

life science↗

NASA Life Sciences Program

This Life Science Program video examines the variety of projects that study both the physiological and psychological impacts on astronauts due to extended space missions. The hazards of space radiation and microgravity effects on the human body are described, along with these effects on plant growth, and the performance of medical procedures in space. One research technique, which is hoped to provide help for future space travel, is the study of aquanauts and their life habits underwater.

Source record↗

Accelerating Nuclear Facility Mission Completion Through an Improved Chemical Hazard Control Strategy - 20460

Code of Federal Regulation (CFR) 10 CFR 830, Nuclear Safety Management [1], explicitly identifies hazardous materials in addition to radioactive materials when establishing the scope of materials that must be evaluated in Hazard Category (HC) 1, 2, and 3 nuclear facilities. This inclusion has led to a near decade-long progression of more and more rigorous application of chemical hazard controls in these facilities. The progressive addition of more rigorous chemical hazard controls has occurred across the Department of Energy (DOE) Complex, having been driven by contractors and regulators alike. However, chemical hazards in other DOE facilities have been, and continue to be, controlled using traditional industrial safety centered strategies. Thus, identical chemical hazards are controlled using dramatically different approaches based solely on the facility type. Not only are the controls different, the analysis and derivation rigor and requirements are also significantly different. In particular, chemical control derivation and application in non-nuclear facilities are much less onerous than the comprehensive hazard analysis process used in nuclear facilities, even in circumstances in which chemicals are not initiators to, or do not exacerbate a nuclear event. While the derivation and control approaches used in these two types of facilities are disparate, the safety results are similarly effective based on a review of reported chemical events from 2014 through 2018. While both approaches achieve comparable safety outcomes, the approach used in nuclear facilities results in significantly greater preparation costs and implementation costs. Furthermore, the problem with the differing approach is not relegated to the control preparation and implementation burden. The operational impact of potentially unnecessary controls slows mission completion without a corresponding increase in safety, not to mention the dilution of the importance of Technical Safety Requirements. The proposed solution must first include a critical and thorough examination of DOE Complex and top-tier chemical industry chemical hazard control practices, coupled with a similar examination of the driving facility regulatory requirements. Results from the examination can then be used to fuel a bold departure from current chemical control practices in Hazard Category 1, 2, and 3 nuclear facilities. Development of an improved and consistent chemical hazard control process would follow, one that continues to ensure safety while accelerating mission completion and significantly reducing the burden associated with chemical hazard control development and implementation. The improved process must establish a hierarchy where radiological hazards are addressed using safety class and safety significant controls and chemical hazards are addressed using overarching safety management programs (with limited unique exceptions). The improved Hazard Category 1,2, and 3 nuclear facility chemical hazard control strategy, while compliant with 10 CFR 830 [1], would be founded on the requirements in 10 CFR 851, Worker Safety and Health Program [2], and the complementary DOE O 151.1D, Comprehensive Emergency Management System [3]. In this way, the Hazard Category 1, 2, and 3 nuclear facility chemical hazard control strategy would, wherever appropriate, be the same process used at other DOE Complex facilities. Ultimately, the improved process will maintain safety and significantly reduce costs and life cycle risk through faster mission completion. (authors)

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

Tug fleet and ground operations schedules and controls. Volume 2: part 2, addenda

The results of a study to assess the tug safing requirements at postlanding are presented. The study considered the normal (green light) conditions from orbiter landing to completion of preparations for the next launch. Normal tug ground turnaround operations include handling and transportation activities and the performance of inspections, tests, and checkout functions. These activities dictate that hazards to ground personnel, the tug, GSE, facilities, and ecology be reduced to the lowest practical level consistent with program objectives, cost, and schedules. During flight operations, the tug contains energy sources that constitute potential hazards but are required for mission accomplishment. These potential hazards have been reduced to an acceptable level for flight operation by design features and by providing for control of energy sources.

Source record↗

Hazards of Lunar Surface Exploration: Determining the Immunogenicity/Allergenicity of Lunar Dust

During the Apollo moon missions, there were consistent reports of lunar dust exposure leading to upper respiratory symptoms in both astronauts and ground support personnel. Crew members and landing vehicles will inevitably be exposed to lunar dust in future lunar missions and the hazards associated with this are essentially unknown. The goal of this study is to determine, in a simple cell culture experiment, if lunar dust has the capacity to serve as an allergen, an adjuvant, or a cellular toxin.

immunology↗

Establishing a Disruptive New Capability for NASA to Fly UAV's into Hazardous Conditions

A 2015 NASA Aeronautics Mission "Seedling" Proposal is described for a Severe-Environment UAV (SE-UAV) that can perform in-situ measurements in hazardous atmospheric conditions like lightning, volcanic ash and radiation. Specifically, this paper describes the design of a proof-of-concept vehicle and measurement system that can survive lightning attachment during flight operations into thunderstorms. Elements from three NASA centers draw together for the SE-UAV concept. 1) The NASA KSC Genesis UAV was developed in collaboration with the DARPA Nimbus program to measure electric field and X-rays present within thunderstorms. 2) A novel NASA LaRC fiber-optic sensor uses Faraday-effect polarization rotation to measure total lightning electric current on an air vehicle fuselage. 3) NASA AFRC's state-of-the-art Fiber Optics and Systems Integration Laboratory is envisioned to transition the Faraday system to a compact, light-weight, all-fiber design. The SE-UAV will provide in-flight lightning electric-current return stroke and recoil leader data, and serve as a platform for development of emerging sensors and new missions into hazardous environments. NASA's Aeronautics and Science Missions are interested in a capability to perform in-situ volcanic plume measurements and long-endurance UAV operations in various weather conditions. (Figure 1 shows an artist concept of a SE-UAV flying near a volcano.) This paper concludes with an overview of the NASA Aeronautics Strategic Vision, Programs, and how a SE-UAV is envisioned to impact them. The SE-UAV concept leverages high-value legacy research products into a new capability for NASA to fly a pathfinder UAV into hazardous conditions, and is presented in the SPIE DSS venue to explore teaming, collaboration and advocacy opportunities outside NASA.

Ely, Jay↗